Cavia porcellus (Guinea pig)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria;

Average proteome isoelectric point is 6.69

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 25080 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|H0W6Z4|H0W6Z4_CAVPO Vesicle-fusing ATPase OS=Cavia porcellus OX=10141 PE=3 SV=2
MM1 pKa = 7.66EE2 pKa = 5.17EE3 pKa = 4.0NSVVLSEE10 pKa = 4.16PLGLLLLPLIAMLLMVLCVRR30 pKa = 11.84CRR32 pKa = 11.84EE33 pKa = 4.06LRR35 pKa = 11.84GSYY38 pKa = 10.62GSASEE43 pKa = 4.42NRR45 pKa = 11.84SQTEE49 pKa = 3.86SFLFKK54 pKa = 8.96PTQMLPSWSPYY65 pKa = 9.37PSAPDD70 pKa = 3.43PHH72 pKa = 8.07LSQPDD77 pKa = 3.84LLHH80 pKa = 6.79IPRR83 pKa = 11.84SPQLLLGSHH92 pKa = 6.8RR93 pKa = 11.84MPSSQQDD100 pKa = 3.01SDD102 pKa = 3.88GANSVASYY110 pKa = 10.49EE111 pKa = 4.22NQEE114 pKa = 4.42VACEE118 pKa = 4.0DD119 pKa = 3.58ADD121 pKa = 4.09KK122 pKa = 11.7DD123 pKa = 3.96EE124 pKa = 6.09DD125 pKa = 3.96EE126 pKa = 4.47EE127 pKa = 5.18DD128 pKa = 4.13YY129 pKa = 11.41PNEE132 pKa = 4.37GYY134 pKa = 10.63GGYY137 pKa = 9.87VEE139 pKa = 5.11VLPDD143 pKa = 3.62STPATSTGVPSAPVPSNPGLRR164 pKa = 11.84DD165 pKa = 3.14SAFSMEE171 pKa = 3.88SRR173 pKa = 11.84DD174 pKa = 3.72YY175 pKa = 11.42VNVPEE180 pKa = 4.5SEE182 pKa = 4.35EE183 pKa = 4.03SAEE186 pKa = 3.99ASLDD190 pKa = 3.47GSLEE194 pKa = 4.1YY195 pKa = 11.41VNVSQEE201 pKa = 4.04LQPLPGTEE209 pKa = 4.06PATLSSQEE217 pKa = 4.09VEE219 pKa = 4.22DD220 pKa = 4.94EE221 pKa = 4.27EE222 pKa = 6.16DD223 pKa = 3.93EE224 pKa = 4.4EE225 pKa = 5.78APDD228 pKa = 3.76YY229 pKa = 11.72EE230 pKa = 4.4NVQEE234 pKa = 4.58LSS236 pKa = 3.31

Molecular weight: 25.74 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A286XJT6|A0A286XJT6_CAVPO Chromosome 5 open reading frame 24 OS=Cavia porcellus OX=10141 GN=C5orf24 PE=3 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

18247

6833

25080

14117386

9

7286

562.9

62.77

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.013 ± 0.015

2.241 ± 0.014

4.856 ± 0.011

7.033 ± 0.02

3.71 ± 0.011

6.409 ± 0.02

2.588 ± 0.007

4.408 ± 0.013

5.684 ± 0.018

10.078 ± 0.021

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.183 ± 0.006

3.579 ± 0.008

6.14 ± 0.02

4.8 ± 0.014

5.634 ± 0.014

8.285 ± 0.021

5.306 ± 0.009

6.137 ± 0.011

1.192 ± 0.006

2.71 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski