Amino acid dipepetide frequency for Chitinophaga parva

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.246AlaAla: 10.246 ± 0.106	0.884AlaCys: 0.884 ± 0.031	5.053AlaAsp: 5.053 ± 0.062	4.057AlaGlu: 4.057 ± 0.05	3.93AlaPhe: 3.93 ± 0.055	7.5AlaGly: 7.5 ± 0.076	1.956AlaHis: 1.956 ± 0.039	5.093AlaIle: 5.093 ± 0.062	3.914AlaLys: 3.914 ± 0.056	8.841AlaLeu: 8.841 ± 0.095	2.307AlaMet: 2.307 ± 0.041	3.807AlaAsn: 3.807 ± 0.052	3.719AlaPro: 3.719 ± 0.057	3.903AlaGln: 3.903 ± 0.049	4.038AlaArg: 4.038 ± 0.055	5.064AlaSer: 5.064 ± 0.068	5.71AlaThr: 5.71 ± 0.106	5.967AlaVal: 5.967 ± 0.065	1.142AlaTrp: 1.142 ± 0.031	3.471AlaTyr: 3.471 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.655CysAla: 0.655 ± 0.027	0.176CysCys: 0.176 ± 0.01	0.382CysAsp: 0.382 ± 0.025	0.347CysGlu: 0.347 ± 0.017	0.395CysPhe: 0.395 ± 0.014	0.694CysGly: 0.694 ± 0.031	0.207CysHis: 0.207 ± 0.012	0.575CysIle: 0.575 ± 0.015	0.435CysLys: 0.435 ± 0.017	0.831CysLeu: 0.831 ± 0.023	0.261CysMet: 0.261 ± 0.01	0.358CysAsn: 0.358 ± 0.016	0.354CysPro: 0.354 ± 0.016	0.27CysGln: 0.27 ± 0.012	0.376CysArg: 0.376 ± 0.015	0.488CysSer: 0.488 ± 0.029	0.494CysThr: 0.494 ± 0.019	0.489CysVal: 0.489 ± 0.019	0.152CysTrp: 0.152 ± 0.009	0.369CysTyr: 0.369 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.104AspAla: 5.104 ± 0.062	0.362AspCys: 0.362 ± 0.015	2.504AspAsp: 2.504 ± 0.039	2.771AspGlu: 2.771 ± 0.047	2.658AspPhe: 2.658 ± 0.037	3.99AspGly: 3.99 ± 0.062	1.195AspHis: 1.195 ± 0.03	3.36AspIle: 3.36 ± 0.049	3.163AspLys: 3.163 ± 0.055	4.899AspLeu: 4.899 ± 0.054	1.214AspMet: 1.214 ± 0.025	2.598AspAsn: 2.598 ± 0.05	2.417AspPro: 2.417 ± 0.039	1.955AspGln: 1.955 ± 0.031	2.289AspArg: 2.289 ± 0.038	2.955AspSer: 2.955 ± 0.053	3.048AspThr: 3.048 ± 0.063	3.615AspVal: 3.615 ± 0.044	0.762AspTrp: 0.762 ± 0.021	2.459AspTyr: 2.459 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	4.646GluAla: 4.646 ± 0.064	0.339GluCys: 0.339 ± 0.019	2.527GluAsp: 2.527 ± 0.042	2.908GluGlu: 2.908 ± 0.062	1.743GluPhe: 1.743 ± 0.038	3.323GluGly: 3.323 ± 0.049	1.21GluHis: 1.21 ± 0.028	3.121GluIle: 3.121 ± 0.05	3.762GluLys: 3.762 ± 0.058	4.776GluLeu: 4.776 ± 0.069	1.408GluMet: 1.408 ± 0.03	2.542GluAsn: 2.542 ± 0.04	1.563GluPro: 1.563 ± 0.034	2.474GluGln: 2.474 ± 0.039	2.488GluArg: 2.488 ± 0.039	2.216GluSer: 2.216 ± 0.04	2.626GluThr: 2.626 ± 0.045	3.456GluVal: 3.456 ± 0.051	0.651GluTrp: 0.651 ± 0.019	1.78GluTyr: 1.78 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.426PheAla: 3.426 ± 0.044	0.428PheCys: 0.428 ± 0.014	2.565PheAsp: 2.565 ± 0.038	2.221PheGlu: 2.221 ± 0.037	2.237PhePhe: 2.237 ± 0.049	3.058PheGly: 3.058 ± 0.046	0.964PheHis: 0.964 ± 0.023	2.642PheIle: 2.642 ± 0.044	2.355PheLys: 2.355 ± 0.039	4.067PheLeu: 4.067 ± 0.061	1.147PheMet: 1.147 ± 0.023	2.575PheAsn: 2.575 ± 0.045	1.872PhePro: 1.872 ± 0.032	1.504PheGln: 1.504 ± 0.029	2.213PheArg: 2.213 ± 0.035	3.18PheSer: 3.18 ± 0.042	3.293PheThr: 3.293 ± 0.053	2.721PheVal: 2.721 ± 0.041	0.54PheTrp: 0.54 ± 0.017	1.931PheTyr: 1.931 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	5.913GlyAla: 5.913 ± 0.069	0.652GlyCys: 0.652 ± 0.026	3.613GlyAsp: 3.613 ± 0.053	3.157GlyGlu: 3.157 ± 0.041	3.463GlyPhe: 3.463 ± 0.046	5.459GlyGly: 5.459 ± 0.071	1.677GlyHis: 1.677 ± 0.033	4.905GlyIle: 4.905 ± 0.066	4.617GlyLys: 4.617 ± 0.047	6.521GlyLeu: 6.521 ± 0.066	1.966GlyMet: 1.966 ± 0.035	3.87GlyAsn: 3.87 ± 0.057	2.088GlyPro: 2.088 ± 0.043	2.908GlyGln: 2.908 ± 0.043	3.249GlyArg: 3.249 ± 0.05	4.484GlySer: 4.484 ± 0.066	4.695GlyThr: 4.695 ± 0.084	4.848GlyVal: 4.848 ± 0.059	1.13GlyTrp: 1.13 ± 0.03	3.324GlyTyr: 3.324 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.905HisAla: 1.905 ± 0.033	0.233HisCys: 0.233 ± 0.012	1.078HisAsp: 1.078 ± 0.027	1.013HisGlu: 1.013 ± 0.025	1.359HisPhe: 1.359 ± 0.028	1.452HisGly: 1.452 ± 0.03	0.719HisHis: 0.719 ± 0.022	1.429HisIle: 1.429 ± 0.03	0.976HisLys: 0.976 ± 0.024	2.352HisLeu: 2.352 ± 0.041	0.518HisMet: 0.518 ± 0.017	1.053HisAsn: 1.053 ± 0.024	1.367HisPro: 1.367 ± 0.028	0.966HisGln: 0.966 ± 0.024	1.12HisArg: 1.12 ± 0.025	1.181HisSer: 1.181 ± 0.028	1.414HisThr: 1.414 ± 0.03	1.322HisVal: 1.322 ± 0.026	0.369HisTrp: 0.369 ± 0.016	1.161HisTyr: 1.161 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.465IleAla: 5.465 ± 0.056	0.58IleCys: 0.58 ± 0.02	3.284IleAsp: 3.284 ± 0.048	2.707IleGlu: 2.707 ± 0.048	2.479IlePhe: 2.479 ± 0.043	4.118IleGly: 4.118 ± 0.051	1.275IleHis: 1.275 ± 0.028	3.494IleIle: 3.494 ± 0.052	2.992IleLys: 2.992 ± 0.051	5.07IleLeu: 5.07 ± 0.071	1.209IleMet: 1.209 ± 0.026	2.99IleAsn: 2.99 ± 0.043	2.838IlePro: 2.838 ± 0.039	2.018IleGln: 2.018 ± 0.038	3.149IleArg: 3.149 ± 0.043	3.98IleSer: 3.98 ± 0.048	4.349IleThr: 4.349 ± 0.071	3.644IleVal: 3.644 ± 0.052	0.639IleTrp: 0.639 ± 0.022	2.128IleTyr: 2.128 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	5.069LysAla: 5.069 ± 0.065	0.269LysCys: 0.269 ± 0.013	3.458LysAsp: 3.458 ± 0.052	3.316LysGlu: 3.316 ± 0.065	1.859LysPhe: 1.859 ± 0.031	4.026LysGly: 4.026 ± 0.056	1.146LysHis: 1.146 ± 0.026	3.183LysIle: 3.183 ± 0.052	3.535LysLys: 3.535 ± 0.061	4.648LysLeu: 4.648 ± 0.053	1.549LysMet: 1.549 ± 0.033	2.553LysAsn: 2.553 ± 0.043	2.432LysPro: 2.432 ± 0.035	2.479LysGln: 2.479 ± 0.038	2.408LysArg: 2.408 ± 0.039	2.655LysSer: 2.655 ± 0.044	3.274LysThr: 3.274 ± 0.044	3.765LysVal: 3.765 ± 0.054	0.674LysTrp: 0.674 ± 0.019	2.059LysTyr: 2.059 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	8.257LeuAla: 8.257 ± 0.081	0.953LeuCys: 0.953 ± 0.026	4.977LeuAsp: 4.977 ± 0.062	5.079LeuGlu: 5.079 ± 0.064	4.244LeuPhe: 4.244 ± 0.064	6.241LeuGly: 6.241 ± 0.065	2.553LeuHis: 2.553 ± 0.043	4.584LeuIle: 4.584 ± 0.061	5.436LeuLys: 5.436 ± 0.06	10.711LeuLeu: 10.711 ± 0.125	2.084LeuMet: 2.084 ± 0.039	4.28LeuAsn: 4.28 ± 0.062	5.07LeuPro: 5.07 ± 0.059	5.479LeuGln: 5.479 ± 0.067	4.897LeuArg: 4.897 ± 0.068	6.094LeuSer: 6.094 ± 0.081	5.408LeuThr: 5.408 ± 0.076	6.372LeuVal: 6.372 ± 0.066	0.977LeuTrp: 0.977 ± 0.03	3.464LeuTyr: 3.464 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	2.255MetAla: 2.255 ± 0.035	0.136MetCys: 0.136 ± 0.008	1.347MetAsp: 1.347 ± 0.031	1.536MetGlu: 1.536 ± 0.028	0.768MetPhe: 0.768 ± 0.019	1.658MetGly: 1.658 ± 0.03	0.595MetHis: 0.595 ± 0.019	1.289MetIle: 1.289 ± 0.026	1.733MetLys: 1.733 ± 0.032	2.378MetLeu: 2.378 ± 0.038	0.612MetMet: 0.612 ± 0.02	1.182MetAsn: 1.182 ± 0.028	1.287MetPro: 1.287 ± 0.024	1.306MetGln: 1.306 ± 0.026	1.185MetArg: 1.185 ± 0.024	1.263MetSer: 1.263 ± 0.027	1.223MetThr: 1.223 ± 0.029	1.532MetVal: 1.532 ± 0.029	0.218MetTrp: 0.218 ± 0.01	0.722MetTyr: 0.722 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	4.372AsnAla: 4.372 ± 0.053	0.365AsnCys: 0.365 ± 0.041	2.537AsnAsp: 2.537 ± 0.034	2.288AsnGlu: 2.288 ± 0.036	2.151AsnPhe: 2.151 ± 0.038	4.062AsnGly: 4.062 ± 0.066	0.876AsnHis: 0.876 ± 0.02	3.229AsnIle: 3.229 ± 0.052	2.555AsnLys: 2.555 ± 0.043	4.201AsnLeu: 4.201 ± 0.065	1.132AsnMet: 1.132 ± 0.025	2.67AsnAsn: 2.67 ± 0.062	2.396AsnPro: 2.396 ± 0.038	1.646AsnGln: 1.646 ± 0.031	2.106AsnArg: 2.106 ± 0.033	2.52AsnSer: 2.52 ± 0.041	3.22AsnThr: 3.22 ± 0.049	3.293AsnVal: 3.293 ± 0.053	0.684AsnTrp: 0.684 ± 0.022	2.22AsnTyr: 2.22 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	5.117ProAla: 5.117 ± 0.086	0.251ProCys: 0.251 ± 0.013	2.901ProAsp: 2.901 ± 0.036	2.768ProGlu: 2.768 ± 0.041	2.023ProPhe: 2.023 ± 0.034	3.861ProGly: 3.861 ± 0.051	0.925ProHis: 0.925 ± 0.026	2.033ProIle: 2.033 ± 0.032	1.766ProLys: 1.766 ± 0.032	4.114ProLeu: 4.114 ± 0.061	0.912ProMet: 0.912 ± 0.023	1.799ProAsn: 1.799 ± 0.039	1.596ProPro: 1.596 ± 0.037	1.674ProGln: 1.674 ± 0.033	1.661ProArg: 1.661 ± 0.033	2.28ProSer: 2.28 ± 0.04	2.191ProThr: 2.191 ± 0.051	3.932ProVal: 3.932 ± 0.052	0.532ProTrp: 0.532 ± 0.018	1.761ProTyr: 1.761 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.843GlnAla: 3.843 ± 0.051	0.279GlnCys: 0.279 ± 0.013	2.127GlnAsp: 2.127 ± 0.037	2.316GlnGlu: 2.316 ± 0.035	1.764GlnPhe: 1.764 ± 0.034	2.597GlnGly: 2.597 ± 0.037	1.36GlnHis: 1.36 ± 0.031	1.893GlnIle: 1.893 ± 0.037	2.0GlnLys: 2.0 ± 0.038	5.022GlnLeu: 5.022 ± 0.062	1.018GlnMet: 1.018 ± 0.026	1.609GlnAsn: 1.609 ± 0.031	2.187GlnPro: 2.187 ± 0.035	3.208GlnGln: 3.208 ± 0.058	2.219GlnArg: 2.219 ± 0.042	2.135GlnSer: 2.135 ± 0.036	2.19GlnThr: 2.19 ± 0.034	3.254GlnVal: 3.254 ± 0.047	0.592GlnTrp: 0.592 ± 0.017	1.961GlnTyr: 1.961 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	3.418ArgAla: 3.418 ± 0.048	0.303ArgCys: 0.303 ± 0.013	2.328ArgAsp: 2.328 ± 0.044	2.599ArgGlu: 2.599 ± 0.046	2.371ArgPhe: 2.371 ± 0.036	2.531ArgGly: 2.531 ± 0.04	1.152ArgHis: 1.152 ± 0.023	3.161ArgIle: 3.161 ± 0.041	2.89ArgLys: 2.89 ± 0.048	4.573ArgLeu: 4.573 ± 0.057	1.341ArgMet: 1.341 ± 0.024	2.499ArgAsn: 2.499 ± 0.039	1.824ArgPro: 1.824 ± 0.032	2.302ArgGln: 2.302 ± 0.046	2.399ArgArg: 2.399 ± 0.047	2.561ArgSer: 2.561 ± 0.039	2.517ArgThr: 2.517 ± 0.039	2.947ArgVal: 2.947 ± 0.042	0.772ArgTrp: 0.772 ± 0.022	2.325ArgTyr: 2.325 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.783SerAla: 4.783 ± 0.063	0.508SerCys: 0.508 ± 0.019	2.74SerAsp: 2.74 ± 0.039	2.233SerGlu: 2.233 ± 0.034	3.03SerPhe: 3.03 ± 0.044	4.781SerGly: 4.781 ± 0.061	1.132SerHis: 1.132 ± 0.025	3.663SerIle: 3.663 ± 0.045	2.662SerLys: 2.662 ± 0.037	6.094SerLeu: 6.094 ± 0.066	1.438SerMet: 1.438 ± 0.025	2.792SerAsn: 2.792 ± 0.047	2.418SerPro: 2.418 ± 0.041	2.084SerGln: 2.084 ± 0.037	2.713SerArg: 2.713 ± 0.042	3.363SerSer: 3.363 ± 0.061	3.559SerThr: 3.559 ± 0.055	4.013SerVal: 4.013 ± 0.057	0.801SerTrp: 0.801 ± 0.022	2.423SerTyr: 2.423 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	6.143ThrAla: 6.143 ± 0.111	0.448ThrCys: 0.448 ± 0.018	3.361ThrAsp: 3.361 ± 0.055	2.56ThrGlu: 2.56 ± 0.037	2.796ThrPhe: 2.796 ± 0.046	5.413ThrGly: 5.413 ± 0.079	1.239ThrHis: 1.239 ± 0.028	3.687ThrIle: 3.687 ± 0.062	2.434ThrLys: 2.434 ± 0.04	6.113ThrLeu: 6.113 ± 0.072	1.17ThrMet: 1.17 ± 0.026	2.578ThrAsn: 2.578 ± 0.054	3.274ThrPro: 3.274 ± 0.056	2.116ThrGln: 2.116 ± 0.032	2.667ThrArg: 2.667 ± 0.043	3.35ThrSer: 3.35 ± 0.053	3.959ThrThr: 3.959 ± 0.075	4.645ThrVal: 4.645 ± 0.096	0.826ThrTrp: 0.826 ± 0.027	2.55ThrTyr: 2.55 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	5.743ValAla: 5.743 ± 0.061	0.63ValCys: 0.63 ± 0.021	3.452ValAsp: 3.452 ± 0.045	3.075ValGlu: 3.075 ± 0.051	2.962ValPhe: 2.962 ± 0.041	3.953ValGly: 3.953 ± 0.051	1.5ValHis: 1.5 ± 0.03	4.279ValIle: 4.279 ± 0.048	4.156ValLys: 4.156 ± 0.053	6.662ValLeu: 6.662 ± 0.067	1.708ValMet: 1.708 ± 0.032	3.568ValAsn: 3.568 ± 0.06	3.105ValPro: 3.105 ± 0.05	2.792ValGln: 2.792 ± 0.046	2.934ValArg: 2.934 ± 0.04	4.315ValSer: 4.315 ± 0.058	4.622ValThr: 4.622 ± 0.085	4.755ValVal: 4.755 ± 0.058	0.78ValTrp: 0.78 ± 0.019	2.707ValTyr: 2.707 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.927TrpAla: 0.927 ± 0.025	0.144TrpCys: 0.144 ± 0.009	0.69TrpAsp: 0.69 ± 0.023	0.731TrpGlu: 0.731 ± 0.021	0.547TrpPhe: 0.547 ± 0.019	0.881TrpGly: 0.881 ± 0.022	0.323TrpHis: 0.323 ± 0.016	0.704TrpIle: 0.704 ± 0.02	0.795TrpLys: 0.795 ± 0.025	1.337TrpLeu: 1.337 ± 0.028	0.401TrpMet: 0.401 ± 0.014	0.712TrpAsn: 0.712 ± 0.022	0.481TrpPro: 0.481 ± 0.017	0.724TrpGln: 0.724 ± 0.026	0.628TrpArg: 0.628 ± 0.021	0.724TrpSer: 0.724 ± 0.023	0.732TrpThr: 0.732 ± 0.03	0.776TrpVal: 0.776 ± 0.023	0.268TrpTrp: 0.268 ± 0.013	0.54TrpTyr: 0.54 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.317TyrAla: 3.317 ± 0.048	0.368TyrCys: 0.368 ± 0.018	2.394TyrAsp: 2.394 ± 0.045	1.876TyrGlu: 1.876 ± 0.034	2.16TyrPhe: 2.16 ± 0.033	2.94TyrGly: 2.94 ± 0.046	0.984TyrHis: 0.984 ± 0.023	2.085TyrIle: 2.085 ± 0.033	2.179TyrLys: 2.179 ± 0.037	3.95TyrLeu: 3.95 ± 0.055	0.831TyrMet: 0.831 ± 0.026	2.491TyrAsn: 2.491 ± 0.052	1.809TyrPro: 1.809 ± 0.035	1.764TyrGln: 1.764 ± 0.032	2.072TyrArg: 2.072 ± 0.037	2.42TyrSer: 2.42 ± 0.042	2.806TyrThr: 2.806 ± 0.05	2.352TyrVal: 2.352 ± 0.035	0.556TyrTrp: 0.556 ± 0.02	1.911TyrTyr: 1.911 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4954 proteins (1802866 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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