Amino acid dipepetide frequency for Tilligerry virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.823AlaAla: 5.823 ± 1.263
0.647AlaCys: 0.647 ± 0.281
3.72AlaAsp: 3.72 ± 0.556
4.529AlaGlu: 4.529 ± 0.781
2.588AlaPhe: 2.588 ± 0.64
2.75AlaGly: 2.75 ± 0.752
1.456AlaHis: 1.456 ± 0.29
4.529AlaIle: 4.529 ± 1.143
2.265AlaLys: 2.265 ± 0.728
7.279AlaLeu: 7.279 ± 1.234
3.559AlaMet: 3.559 ± 0.897
4.044AlaAsn: 4.044 ± 0.601
2.103AlaPro: 2.103 ± 0.578
1.941AlaGln: 1.941 ± 0.453
4.368AlaArg: 4.368 ± 0.52
3.073AlaSer: 3.073 ± 0.304
3.882AlaThr: 3.882 ± 0.789
4.691AlaVal: 4.691 ± 0.834
1.132AlaTrp: 1.132 ± 0.286
2.912AlaTyr: 2.912 ± 0.703
0.0AlaXaa: 0.0 ± 0.0
Cys
0.971CysAla: 0.971 ± 0.469
0.162CysCys: 0.162 ± 0.159
0.647CysAsp: 0.647 ± 0.324
0.647CysGlu: 0.647 ± 0.302
0.971CysPhe: 0.971 ± 0.338
0.971CysGly: 0.971 ± 0.463
0.162CysHis: 0.162 ± 0.14
0.647CysIle: 0.647 ± 0.343
0.647CysLys: 0.647 ± 0.391
0.971CysLeu: 0.971 ± 0.261
0.324CysMet: 0.324 ± 0.152
0.324CysAsn: 0.324 ± 0.202
0.485CysPro: 0.485 ± 0.243
0.485CysGln: 0.485 ± 0.256
0.809CysArg: 0.809 ± 0.425
0.971CysSer: 0.971 ± 0.28
0.324CysThr: 0.324 ± 0.327
0.971CysVal: 0.971 ± 0.381
0.324CysTrp: 0.324 ± 0.191
0.324CysTyr: 0.324 ± 0.211
0.0CysXaa: 0.0 ± 0.0
Asp
2.75AspAla: 2.75 ± 0.396
0.809AspCys: 0.809 ± 0.358
4.691AspAsp: 4.691 ± 0.915
5.176AspGlu: 5.176 ± 1.187
2.912AspPhe: 2.912 ± 0.541
4.206AspGly: 4.206 ± 0.491
1.618AspHis: 1.618 ± 0.548
4.691AspIle: 4.691 ± 0.784
2.426AspLys: 2.426 ± 0.986
5.338AspLeu: 5.338 ± 0.753
1.941AspMet: 1.941 ± 0.742
1.618AspAsn: 1.618 ± 0.352
2.103AspPro: 2.103 ± 0.586
1.294AspGln: 1.294 ± 0.326
3.72AspArg: 3.72 ± 0.74
3.073AspSer: 3.073 ± 0.811
2.912AspThr: 2.912 ± 0.703
5.985AspVal: 5.985 ± 0.922
0.971AspTrp: 0.971 ± 0.529
2.426AspTyr: 2.426 ± 0.395
0.0AspXaa: 0.0 ± 0.0
Glu
4.853GluAla: 4.853 ± 0.788
0.162GluCys: 0.162 ± 0.159
3.72GluAsp: 3.72 ± 0.545
9.706GluGlu: 9.706 ± 2.273
2.265GluPhe: 2.265 ± 0.439
4.368GluGly: 4.368 ± 0.568
1.294GluHis: 1.294 ± 0.445
5.176GluIle: 5.176 ± 0.808
4.206GluLys: 4.206 ± 0.848
6.309GluLeu: 6.309 ± 1.0
2.426GluMet: 2.426 ± 0.463
2.103GluAsn: 2.103 ± 0.491
2.426GluPro: 2.426 ± 0.963
1.941GluGln: 1.941 ± 0.367
5.662GluArg: 5.662 ± 0.651
4.853GluSer: 4.853 ± 0.963
4.368GluThr: 4.368 ± 0.585
5.5GluVal: 5.5 ± 0.767
1.618GluTrp: 1.618 ± 0.562
3.235GluTyr: 3.235 ± 0.725
0.0GluXaa: 0.0 ± 0.0
Phe
1.779PheAla: 1.779 ± 0.333
0.162PheCys: 0.162 ± 0.14
4.044PheAsp: 4.044 ± 0.594
2.103PheGlu: 2.103 ± 0.535
1.456PhePhe: 1.456 ± 0.4
3.882PheGly: 3.882 ± 0.628
1.294PheHis: 1.294 ± 0.249
2.426PheIle: 2.426 ± 0.554
1.294PheLys: 1.294 ± 0.493
4.044PheLeu: 4.044 ± 0.66
0.809PheMet: 0.809 ± 0.325
1.132PheAsn: 1.132 ± 0.359
1.294PhePro: 1.294 ± 0.36
0.809PheGln: 0.809 ± 0.294
2.265PheArg: 2.265 ± 0.925
3.559PheSer: 3.559 ± 0.763
2.588PheThr: 2.588 ± 0.751
1.941PheVal: 1.941 ± 0.53
0.647PheTrp: 0.647 ± 0.202
1.456PheTyr: 1.456 ± 0.417
0.0PheXaa: 0.0 ± 0.0
Gly
4.853GlyAla: 4.853 ± 0.798
0.809GlyCys: 0.809 ± 0.383
4.044GlyAsp: 4.044 ± 0.907
3.882GlyGlu: 3.882 ± 1.139
2.75GlyPhe: 2.75 ± 0.782
3.882GlyGly: 3.882 ± 1.175
1.618GlyHis: 1.618 ± 0.314
3.72GlyIle: 3.72 ± 0.78
4.853GlyLys: 4.853 ± 1.171
5.5GlyLeu: 5.5 ± 0.893
1.132GlyMet: 1.132 ± 0.38
1.779GlyAsn: 1.779 ± 0.579
2.265GlyPro: 2.265 ± 0.458
2.265GlyGln: 2.265 ± 0.582
4.853GlyArg: 4.853 ± 0.937
2.912GlySer: 2.912 ± 0.677
2.75GlyThr: 2.75 ± 0.504
5.015GlyVal: 5.015 ± 1.022
1.294GlyTrp: 1.294 ± 0.373
2.265GlyTyr: 2.265 ± 0.683
0.0GlyXaa: 0.0 ± 0.0
His
2.103HisAla: 2.103 ± 0.534
0.647HisCys: 0.647 ± 0.23
0.485HisAsp: 0.485 ± 0.204
1.941HisGlu: 1.941 ± 0.519
0.809HisPhe: 0.809 ± 0.302
1.941HisGly: 1.941 ± 0.53
1.132HisHis: 1.132 ± 0.396
1.456HisIle: 1.456 ± 0.41
1.294HisLys: 1.294 ± 0.577
2.426HisLeu: 2.426 ± 0.63
0.809HisMet: 0.809 ± 0.418
0.324HisAsn: 0.324 ± 0.196
1.132HisPro: 1.132 ± 0.445
0.809HisGln: 0.809 ± 0.232
0.809HisArg: 0.809 ± 0.367
1.294HisSer: 1.294 ± 0.375
1.294HisThr: 1.294 ± 0.487
1.941HisVal: 1.941 ± 0.607
0.485HisTrp: 0.485 ± 0.308
0.809HisTyr: 0.809 ± 0.279
0.0HisXaa: 0.0 ± 0.0
Ile
4.206IleAla: 4.206 ± 0.545
1.132IleCys: 1.132 ± 0.435
4.206IleAsp: 4.206 ± 1.009
3.72IleGlu: 3.72 ± 0.507
2.103IlePhe: 2.103 ± 0.665
2.426IleGly: 2.426 ± 0.51
1.941IleHis: 1.941 ± 0.53
2.912IleIle: 2.912 ± 0.49
3.397IleLys: 3.397 ± 0.802
6.309IleLeu: 6.309 ± 0.901
2.75IleMet: 2.75 ± 0.43
3.073IleAsn: 3.073 ± 0.926
2.426IlePro: 2.426 ± 0.744
2.912IleGln: 2.912 ± 0.744
4.368IleArg: 4.368 ± 0.768
2.588IleSer: 2.588 ± 0.622
2.75IleThr: 2.75 ± 0.706
4.853IleVal: 4.853 ± 0.666
0.971IleTrp: 0.971 ± 0.43
3.073IleTyr: 3.073 ± 0.672
0.0IleXaa: 0.0 ± 0.0
Lys
3.559LysAla: 3.559 ± 0.655
0.647LysCys: 0.647 ± 0.28
3.397LysAsp: 3.397 ± 0.851
4.691LysGlu: 4.691 ± 1.343
1.779LysPhe: 1.779 ± 0.56
3.559LysGly: 3.559 ± 1.0
0.647LysHis: 0.647 ± 0.194
3.559LysIle: 3.559 ± 1.067
5.5LysLys: 5.5 ± 1.459
5.176LysLeu: 5.176 ± 0.991
1.132LysMet: 1.132 ± 0.402
1.456LysAsn: 1.456 ± 0.293
1.456LysPro: 1.456 ± 0.406
2.103LysGln: 2.103 ± 0.599
5.338LysArg: 5.338 ± 0.76
2.912LysSer: 2.912 ± 0.533
3.882LysThr: 3.882 ± 0.76
4.529LysVal: 4.529 ± 0.722
0.324LysTrp: 0.324 ± 0.327
2.265LysTyr: 2.265 ± 0.517
0.0LysXaa: 0.0 ± 0.0
Leu
6.794LeuAla: 6.794 ± 0.638
1.132LeuCys: 1.132 ± 0.611
6.309LeuAsp: 6.309 ± 0.798
6.309LeuGlu: 6.309 ± 0.697
2.588LeuPhe: 2.588 ± 0.466
4.206LeuGly: 4.206 ± 0.88
1.618LeuHis: 1.618 ± 0.404
5.662LeuIle: 5.662 ± 0.801
6.147LeuLys: 6.147 ± 0.876
5.176LeuLeu: 5.176 ± 0.933
3.397LeuMet: 3.397 ± 0.811
4.529LeuAsn: 4.529 ± 1.063
3.882LeuPro: 3.882 ± 0.786
2.588LeuGln: 2.588 ± 0.97
6.956LeuArg: 6.956 ± 0.742
5.5LeuSer: 5.5 ± 0.641
4.206LeuThr: 4.206 ± 0.631
5.338LeuVal: 5.338 ± 0.968
1.456LeuTrp: 1.456 ± 0.403
1.941LeuTyr: 1.941 ± 0.664
0.0LeuXaa: 0.0 ± 0.0
Met
2.588MetAla: 2.588 ± 0.792
0.485MetCys: 0.485 ± 0.237
1.456MetAsp: 1.456 ± 0.304
2.588MetGlu: 2.588 ± 0.424
1.779MetPhe: 1.779 ± 0.252
1.779MetGly: 1.779 ± 0.563
0.647MetHis: 0.647 ± 0.305
1.941MetIle: 1.941 ± 0.421
2.75MetLys: 2.75 ± 0.752
3.882MetLeu: 3.882 ± 0.936
1.779MetMet: 1.779 ± 0.531
1.941MetAsn: 1.941 ± 0.545
0.647MetPro: 0.647 ± 0.274
2.103MetGln: 2.103 ± 0.713
2.912MetArg: 2.912 ± 0.518
2.75MetSer: 2.75 ± 0.532
2.103MetThr: 2.103 ± 0.463
2.588MetVal: 2.588 ± 0.463
0.162MetTrp: 0.162 ± 0.164
1.132MetTyr: 1.132 ± 0.538
0.0MetXaa: 0.0 ± 0.0
Asn
1.941AsnAla: 1.941 ± 0.601
0.809AsnCys: 0.809 ± 0.48
2.75AsnAsp: 2.75 ± 0.636
2.912AsnGlu: 2.912 ± 0.363
1.618AsnPhe: 1.618 ± 0.25
2.426AsnGly: 2.426 ± 0.787
0.485AsnHis: 0.485 ± 0.355
3.397AsnIle: 3.397 ± 0.729
1.618AsnLys: 1.618 ± 0.419
2.426AsnLeu: 2.426 ± 0.547
1.941AsnMet: 1.941 ± 0.852
1.294AsnAsn: 1.294 ± 0.444
2.75AsnPro: 2.75 ± 0.73
1.456AsnGln: 1.456 ± 0.471
2.265AsnArg: 2.265 ± 0.68
1.294AsnSer: 1.294 ± 0.596
2.265AsnThr: 2.265 ± 0.612
4.529AsnVal: 4.529 ± 0.669
0.324AsnTrp: 0.324 ± 0.203
1.132AsnTyr: 1.132 ± 0.33
0.0AsnXaa: 0.0 ± 0.0
Pro
2.103ProAla: 2.103 ± 0.675
0.162ProCys: 0.162 ± 0.14
2.426ProAsp: 2.426 ± 0.559
2.588ProGlu: 2.588 ± 0.479
1.456ProPhe: 1.456 ± 0.453
1.456ProGly: 1.456 ± 0.525
0.809ProHis: 0.809 ± 0.348
2.912ProIle: 2.912 ± 0.513
1.779ProLys: 1.779 ± 0.441
3.235ProLeu: 3.235 ± 0.478
1.779ProMet: 1.779 ± 0.357
2.265ProAsn: 2.265 ± 0.607
2.265ProPro: 2.265 ± 0.524
2.103ProGln: 2.103 ± 0.453
2.912ProArg: 2.912 ± 0.773
3.073ProSer: 3.073 ± 0.833
2.912ProThr: 2.912 ± 1.208
1.618ProVal: 1.618 ± 0.673
0.324ProTrp: 0.324 ± 0.214
1.456ProTyr: 1.456 ± 0.384
0.0ProXaa: 0.0 ± 0.0
Gln
3.559GlnAla: 3.559 ± 0.916
0.324GlnCys: 0.324 ± 0.201
1.941GlnAsp: 1.941 ± 0.259
2.588GlnGlu: 2.588 ± 0.496
0.971GlnPhe: 0.971 ± 0.389
1.779GlnGly: 1.779 ± 0.6
1.132GlnHis: 1.132 ± 0.439
2.265GlnIle: 2.265 ± 0.527
1.456GlnLys: 1.456 ± 0.422
3.073GlnLeu: 3.073 ± 0.601
1.294GlnMet: 1.294 ± 0.481
1.132GlnAsn: 1.132 ± 0.337
1.294GlnPro: 1.294 ± 0.368
0.485GlnGln: 0.485 ± 0.36
2.75GlnArg: 2.75 ± 0.823
1.132GlnSer: 1.132 ± 0.246
1.779GlnThr: 1.779 ± 0.324
1.456GlnVal: 1.456 ± 0.177
0.324GlnTrp: 0.324 ± 0.196
1.132GlnTyr: 1.132 ± 0.588
0.0GlnXaa: 0.0 ± 0.0
Arg
5.015ArgAla: 5.015 ± 0.674
1.294ArgCys: 1.294 ± 0.658
5.015ArgAsp: 5.015 ± 0.579
5.5ArgGlu: 5.5 ± 1.074
3.397ArgPhe: 3.397 ± 0.518
4.206ArgGly: 4.206 ± 0.701
0.971ArgHis: 0.971 ± 0.493
5.176ArgIle: 5.176 ± 1.283
3.72ArgLys: 3.72 ± 0.689
5.662ArgLeu: 5.662 ± 1.143
2.426ArgMet: 2.426 ± 0.581
3.073ArgAsn: 3.073 ± 0.861
1.294ArgPro: 1.294 ± 0.354
1.941ArgGln: 1.941 ± 0.465
4.368ArgArg: 4.368 ± 0.538
3.882ArgSer: 3.882 ± 0.471
3.397ArgThr: 3.397 ± 0.693
4.529ArgVal: 4.529 ± 1.069
1.294ArgTrp: 1.294 ± 0.474
3.235ArgTyr: 3.235 ± 0.615
0.0ArgXaa: 0.0 ± 0.0
Ser
4.206SerAla: 4.206 ± 1.117
0.485SerCys: 0.485 ± 0.227
2.265SerAsp: 2.265 ± 0.293
4.529SerGlu: 4.529 ± 0.437
2.588SerPhe: 2.588 ± 0.534
4.368SerGly: 4.368 ± 1.383
2.103SerHis: 2.103 ± 0.592
3.397SerIle: 3.397 ± 0.907
4.044SerLys: 4.044 ± 0.986
3.882SerLeu: 3.882 ± 0.61
2.426SerMet: 2.426 ± 0.518
1.294SerAsn: 1.294 ± 0.271
2.426SerPro: 2.426 ± 0.7
1.618SerGln: 1.618 ± 0.561
3.397SerArg: 3.397 ± 0.832
4.044SerSer: 4.044 ± 0.953
3.72SerThr: 3.72 ± 0.807
4.368SerVal: 4.368 ± 0.902
1.294SerTrp: 1.294 ± 0.328
1.941SerTyr: 1.941 ± 0.248
0.0SerXaa: 0.0 ± 0.0
Thr
3.235ThrAla: 3.235 ± 0.756
0.809ThrCys: 0.809 ± 0.286
2.265ThrAsp: 2.265 ± 0.62
3.397ThrGlu: 3.397 ± 0.815
1.941ThrPhe: 1.941 ± 0.344
3.559ThrGly: 3.559 ± 0.739
1.618ThrHis: 1.618 ± 0.462
3.559ThrIle: 3.559 ± 0.913
3.235ThrLys: 3.235 ± 0.543
5.338ThrLeu: 5.338 ± 1.254
1.941ThrMet: 1.941 ± 0.366
2.912ThrAsn: 2.912 ± 0.975
2.912ThrPro: 2.912 ± 0.564
2.426ThrGln: 2.426 ± 0.659
2.75ThrArg: 2.75 ± 0.631
3.72ThrSer: 3.72 ± 0.633
2.265ThrThr: 2.265 ± 0.476
3.882ThrVal: 3.882 ± 0.48
1.132ThrTrp: 1.132 ± 0.351
0.971ThrTyr: 0.971 ± 0.629
0.0ThrXaa: 0.0 ± 0.0
Val
4.529ValAla: 4.529 ± 0.854
0.162ValCys: 0.162 ± 0.165
4.044ValAsp: 4.044 ± 0.512
5.985ValGlu: 5.985 ± 0.714
2.426ValPhe: 2.426 ± 0.49
5.823ValGly: 5.823 ± 0.923
1.779ValHis: 1.779 ± 0.534
2.588ValIle: 2.588 ± 0.458
4.853ValLys: 4.853 ± 0.593
6.794ValLeu: 6.794 ± 0.979
3.559ValMet: 3.559 ± 0.743
2.265ValAsn: 2.265 ± 0.35
4.206ValPro: 4.206 ± 0.868
1.779ValGln: 1.779 ± 0.615
5.662ValArg: 5.662 ± 0.71
4.529ValSer: 4.529 ± 0.642
3.882ValThr: 3.882 ± 0.807
3.397ValVal: 3.397 ± 0.76
0.324ValTrp: 0.324 ± 0.192
2.588ValTyr: 2.588 ± 0.313
0.0ValXaa: 0.0 ± 0.0
Trp
0.485TrpAla: 0.485 ± 0.237
0.162TrpCys: 0.162 ± 0.164
1.456TrpAsp: 1.456 ± 0.65
1.132TrpGlu: 1.132 ± 0.379
0.971TrpPhe: 0.971 ± 0.297
1.456TrpGly: 1.456 ± 0.36
0.809TrpHis: 0.809 ± 0.504
0.647TrpIle: 0.647 ± 0.302
1.294TrpLys: 1.294 ± 0.292
1.294TrpLeu: 1.294 ± 0.694
0.647TrpMet: 0.647 ± 0.341
0.971TrpAsn: 0.971 ± 0.64
0.0TrpPro: 0.0 ± 0.0
0.162TrpGln: 0.162 ± 0.14
0.162TrpArg: 0.162 ± 0.157
0.809TrpSer: 0.809 ± 0.285
0.809TrpThr: 0.809 ± 0.324
0.971TrpVal: 0.971 ± 0.281
0.162TrpTrp: 0.162 ± 0.164
0.324TrpTyr: 0.324 ± 0.201
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.941TyrAla: 1.941 ± 0.514
1.132TyrCys: 1.132 ± 0.456
1.779TyrAsp: 1.779 ± 0.419
2.265TyrGlu: 2.265 ± 0.828
1.618TyrPhe: 1.618 ± 0.477
3.397TyrGly: 3.397 ± 0.807
0.809TyrHis: 0.809 ± 0.431
1.456TyrIle: 1.456 ± 0.484
1.132TyrLys: 1.132 ± 0.4
1.618TyrLeu: 1.618 ± 0.66
1.779TyrMet: 1.779 ± 0.793
2.103TyrAsn: 2.103 ± 0.589
2.265TyrPro: 2.265 ± 0.475
0.647TyrGln: 0.647 ± 0.264
3.235TyrArg: 3.235 ± 0.683
2.426TyrSer: 2.426 ± 0.672
1.779TyrThr: 1.779 ± 0.504
3.073TyrVal: 3.073 ± 0.58
0.162TyrTrp: 0.162 ± 0.164
1.294TyrTyr: 1.294 ± 0.496
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (6183 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski