Amino acid dipepetide frequency for Pseudoscardovia suis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.123AlaAla: 15.123 ± 0.269	1.251AlaCys: 1.251 ± 0.051	8.063AlaAsp: 8.063 ± 0.132	5.479AlaGlu: 5.479 ± 0.098	3.318AlaPhe: 3.318 ± 0.08	8.854AlaGly: 8.854 ± 0.153	2.664AlaHis: 2.664 ± 0.068	5.418AlaIle: 5.418 ± 0.103	4.264AlaLys: 4.264 ± 0.1	9.879AlaLeu: 9.879 ± 0.163	3.135AlaMet: 3.135 ± 0.083	3.515AlaAsn: 3.515 ± 0.085	4.892AlaPro: 4.892 ± 0.131	5.804AlaGln: 5.804 ± 0.133	6.327AlaArg: 6.327 ± 0.118	8.105AlaSer: 8.105 ± 0.149	7.004AlaThr: 7.004 ± 0.141	8.478AlaVal: 8.478 ± 0.145	1.563AlaTrp: 1.563 ± 0.062	2.625AlaTyr: 2.625 ± 0.061	0.006AlaXaa: 0.006 ± 0.003
Cys	1.273CysAla: 1.273 ± 0.049	0.164CysCys: 0.164 ± 0.019	0.721CysAsp: 0.721 ± 0.034	0.526CysGlu: 0.526 ± 0.031	0.35CysPhe: 0.35 ± 0.03	1.063CysGly: 1.063 ± 0.044	0.225CysHis: 0.225 ± 0.021	0.531CysIle: 0.531 ± 0.032	0.323CysLys: 0.323 ± 0.025	0.87CysLeu: 0.87 ± 0.044	0.328CysMet: 0.328 ± 0.025	0.256CysAsn: 0.256 ± 0.024	0.528CysPro: 0.528 ± 0.03	0.262CysGln: 0.262 ± 0.023	0.531CysArg: 0.531 ± 0.035	0.61CysSer: 0.61 ± 0.034	0.684CysThr: 0.684 ± 0.036	0.924CysVal: 0.924 ± 0.041	0.155CysTrp: 0.155 ± 0.015	0.276CysTyr: 0.276 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	8.876AspAla: 8.876 ± 0.159	0.615AspCys: 0.615 ± 0.035	5.193AspAsp: 5.193 ± 0.118	4.614AspGlu: 4.614 ± 0.113	2.219AspPhe: 2.219 ± 0.068	6.609AspGly: 6.609 ± 0.143	1.187AspHis: 1.187 ± 0.046	2.926AspIle: 2.926 ± 0.071	2.155AspLys: 2.155 ± 0.068	4.796AspLeu: 4.796 ± 0.104	1.707AspMet: 1.707 ± 0.053	1.738AspAsn: 1.738 ± 0.065	3.796AspPro: 3.796 ± 0.086	1.75AspGln: 1.75 ± 0.057	3.179AspArg: 3.179 ± 0.105	5.24AspSer: 5.24 ± 0.116	3.96AspThr: 3.96 ± 0.087	5.256AspVal: 5.256 ± 0.107	0.984AspTrp: 0.984 ± 0.037	1.891AspTyr: 1.891 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	5.844GluAla: 5.844 ± 0.101	0.503GluCys: 0.503 ± 0.034	3.22GluAsp: 3.22 ± 0.087	3.04GluGlu: 3.04 ± 0.087	1.702GluPhe: 1.702 ± 0.052	3.799GluGly: 3.799 ± 0.092	1.337GluHis: 1.337 ± 0.051	2.284GluIle: 2.284 ± 0.069	2.116GluLys: 2.116 ± 0.07	4.431GluLeu: 4.431 ± 0.105	1.224GluMet: 1.224 ± 0.048	1.727GluAsn: 1.727 ± 0.057	2.444GluPro: 2.444 ± 0.057	2.384GluGln: 2.384 ± 0.07	3.761GluArg: 3.761 ± 0.087	3.743GluSer: 3.743 ± 0.094	2.976GluThr: 2.976 ± 0.069	3.106GluVal: 3.106 ± 0.084	0.79GluTrp: 0.79 ± 0.035	1.56GluTyr: 1.56 ± 0.057	0.0GluXaa: 0.0 ± 0.0
Phe	3.602PheAla: 3.602 ± 0.084	0.337PheCys: 0.337 ± 0.026	2.484PheAsp: 2.484 ± 0.069	1.666PheGlu: 1.666 ± 0.055	1.101PhePhe: 1.101 ± 0.046	2.882PheGly: 2.882 ± 0.075	0.764PheHis: 0.764 ± 0.034	1.61PheIle: 1.61 ± 0.064	0.854PheLys: 0.854 ± 0.039	2.534PheLeu: 2.534 ± 0.084	0.689PheMet: 0.689 ± 0.036	0.984PheAsn: 0.984 ± 0.037	1.355PhePro: 1.355 ± 0.051	0.863PheGln: 0.863 ± 0.04	1.561PheArg: 1.561 ± 0.052	2.05PheSer: 2.05 ± 0.074	2.167PheThr: 2.167 ± 0.067	2.537PheVal: 2.537 ± 0.074	0.376PheTrp: 0.376 ± 0.026	0.785PheTyr: 0.785 ± 0.039	0.002PheXaa: 0.002 ± 0.002
Gly	8.221GlyAla: 8.221 ± 0.145	0.824GlyCys: 0.824 ± 0.04	5.148GlyAsp: 5.148 ± 0.101	4.158GlyGlu: 4.158 ± 0.092	2.982GlyPhe: 2.982 ± 0.078	6.108GlyGly: 6.108 ± 0.121	1.658GlyHis: 1.658 ± 0.056	4.648GlyIle: 4.648 ± 0.084	3.602GlyLys: 3.602 ± 0.079	6.373GlyLeu: 6.373 ± 0.125	2.344GlyMet: 2.344 ± 0.072	2.803GlyAsn: 2.803 ± 0.077	2.269GlyPro: 2.269 ± 0.073	2.492GlyGln: 2.492 ± 0.073	4.481GlyArg: 4.481 ± 0.084	5.733GlySer: 5.733 ± 0.129	5.727GlyThr: 5.727 ± 0.12	6.472GlyVal: 6.472 ± 0.099	1.18GlyTrp: 1.18 ± 0.046	2.533GlyTyr: 2.533 ± 0.084	0.0GlyXaa: 0.0 ± 0.0
His	2.522HisAla: 2.522 ± 0.085	0.234HisCys: 0.234 ± 0.017	1.724HisAsp: 1.724 ± 0.055	1.218HisGlu: 1.218 ± 0.047	0.623HisPhe: 0.623 ± 0.035	2.162HisGly: 2.162 ± 0.073	0.637HisHis: 0.637 ± 0.037	1.066HisIle: 1.066 ± 0.049	0.756HisLys: 0.756 ± 0.034	1.469HisLeu: 1.469 ± 0.048	0.559HisMet: 0.559 ± 0.028	0.842HisAsn: 0.842 ± 0.052	1.43HisPro: 1.43 ± 0.056	0.668HisGln: 0.668 ± 0.037	1.579HisArg: 1.579 ± 0.058	1.39HisSer: 1.39 ± 0.05	1.436HisThr: 1.436 ± 0.058	1.869HisVal: 1.869 ± 0.064	0.323HisTrp: 0.323 ± 0.023	0.603HisTyr: 0.603 ± 0.032	0.003HisXaa: 0.003 ± 0.004
Ile	6.341IleAla: 6.341 ± 0.11	0.625IleCys: 0.625 ± 0.033	3.783IleAsp: 3.783 ± 0.086	2.67IleGlu: 2.67 ± 0.067	1.205IlePhe: 1.205 ± 0.044	4.077IleGly: 4.077 ± 0.094	0.995IleHis: 0.995 ± 0.043	2.728IleIle: 2.728 ± 0.08	1.568IleLys: 1.568 ± 0.054	3.313IleLeu: 3.313 ± 0.084	1.091IleMet: 1.091 ± 0.045	1.616IleAsn: 1.616 ± 0.06	2.554IlePro: 2.554 ± 0.065	1.251IleGln: 1.251 ± 0.05	2.712IleArg: 2.712 ± 0.066	3.024IleSer: 3.024 ± 0.08	3.237IleThr: 3.237 ± 0.077	4.567IleVal: 4.567 ± 0.09	0.473IleTrp: 0.473 ± 0.028	1.07IleTyr: 1.07 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.369LysAla: 4.369 ± 0.101	0.205LysCys: 0.205 ± 0.02	2.417LysAsp: 2.417 ± 0.089	1.936LysGlu: 1.936 ± 0.064	0.823LysPhe: 0.823 ± 0.034	2.5LysGly: 2.5 ± 0.069	0.879LysHis: 0.879 ± 0.042	1.544LysIle: 1.544 ± 0.057	1.636LysLys: 1.636 ± 0.062	2.929LysLeu: 2.929 ± 0.079	0.704LysMet: 0.704 ± 0.036	1.355LysAsn: 1.355 ± 0.047	2.161LysPro: 2.161 ± 0.061	1.536LysGln: 1.536 ± 0.051	2.369LysArg: 2.369 ± 0.061	2.155LysSer: 2.155 ± 0.064	2.333LysThr: 2.333 ± 0.076	2.4LysVal: 2.4 ± 0.074	0.393LysTrp: 0.393 ± 0.026	0.938LysTyr: 0.938 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	9.847LeuAla: 9.847 ± 0.156	1.176LeuCys: 1.176 ± 0.048	5.805LeuAsp: 5.805 ± 0.109	4.008LeuGlu: 4.008 ± 0.093	2.553LeuPhe: 2.553 ± 0.076	6.628LeuGly: 6.628 ± 0.113	1.916LeuHis: 1.916 ± 0.059	3.916LeuIle: 3.916 ± 0.096	2.818LeuLys: 2.818 ± 0.073	6.945LeuLeu: 6.945 ± 0.141	1.93LeuMet: 1.93 ± 0.061	2.436LeuAsn: 2.436 ± 0.06	4.247LeuPro: 4.247 ± 0.081	2.554LeuGln: 2.554 ± 0.065	5.323LeuArg: 5.323 ± 0.091	5.404LeuSer: 5.404 ± 0.112	5.196LeuThr: 5.196 ± 0.094	6.275LeuVal: 6.275 ± 0.125	0.97LeuTrp: 0.97 ± 0.045	1.95LeuTyr: 1.95 ± 0.061	0.0LeuXaa: 0.0 ± 0.0
Met	2.643MetAla: 2.643 ± 0.078	0.298MetCys: 0.298 ± 0.028	1.421MetAsp: 1.421 ± 0.051	1.252MetGlu: 1.252 ± 0.05	0.732MetPhe: 0.732 ± 0.034	1.814MetGly: 1.814 ± 0.056	0.65MetHis: 0.65 ± 0.031	1.118MetIle: 1.118 ± 0.048	0.884MetLys: 0.884 ± 0.037	2.298MetLeu: 2.298 ± 0.062	0.635MetMet: 0.635 ± 0.029	0.874MetAsn: 0.874 ± 0.035	1.568MetPro: 1.568 ± 0.061	0.849MetGln: 0.849 ± 0.034	1.791MetArg: 1.791 ± 0.063	1.891MetSer: 1.891 ± 0.053	1.88MetThr: 1.88 ± 0.045	1.686MetVal: 1.686 ± 0.061	0.297MetTrp: 0.297 ± 0.021	0.504MetTyr: 0.504 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	4.013AsnAla: 4.013 ± 0.097	0.262AsnCys: 0.262 ± 0.021	2.061AsnAsp: 2.061 ± 0.075	1.535AsnGlu: 1.535 ± 0.048	0.835AsnPhe: 0.835 ± 0.04	3.166AsnGly: 3.166 ± 0.087	0.628AsnHis: 0.628 ± 0.034	1.385AsnIle: 1.385 ± 0.048	1.137AsnLys: 1.137 ± 0.047	2.448AsnLeu: 2.448 ± 0.067	0.693AsnMet: 0.693 ± 0.035	1.041AsnAsn: 1.041 ± 0.047	2.272AsnPro: 2.272 ± 0.066	0.912AsnGln: 0.912 ± 0.041	1.835AsnArg: 1.835 ± 0.058	2.045AsnSer: 2.045 ± 0.067	2.147AsnThr: 2.147 ± 0.063	2.255AsnVal: 2.255 ± 0.064	0.411AsnTrp: 0.411 ± 0.026	0.77AsnTyr: 0.77 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	5.434ProAla: 5.434 ± 0.12	0.453ProCys: 0.453 ± 0.027	3.566ProAsp: 3.566 ± 0.083	2.778ProGlu: 2.778 ± 0.065	1.491ProPhe: 1.491 ± 0.048	3.793ProGly: 3.793 ± 0.087	1.13ProHis: 1.13 ± 0.052	2.086ProIle: 2.086 ± 0.055	1.577ProLys: 1.577 ± 0.064	3.593ProLeu: 3.593 ± 0.089	1.073ProMet: 1.073 ± 0.044	1.474ProAsn: 1.474 ± 0.054	1.449ProPro: 1.449 ± 0.092	2.498ProGln: 2.498 ± 0.097	2.757ProArg: 2.757 ± 0.086	3.549ProSer: 3.549 ± 0.097	3.191ProThr: 3.191 ± 0.081	3.875ProVal: 3.875 ± 0.11	0.665ProTrp: 0.665 ± 0.032	1.319ProTyr: 1.319 ± 0.046	0.0ProXaa: 0.0 ± 0.0
Gln	4.648GlnAla: 4.648 ± 0.124	0.336GlnCys: 0.336 ± 0.023	2.038GlnAsp: 2.038 ± 0.057	1.836GlnGlu: 1.836 ± 0.058	1.041GlnPhe: 1.041 ± 0.041	2.787GlnGly: 2.787 ± 0.08	0.863GlnHis: 0.863 ± 0.035	1.889GlnIle: 1.889 ± 0.061	1.146GlnLys: 1.146 ± 0.048	3.382GlnLeu: 3.382 ± 0.089	1.048GlnMet: 1.048 ± 0.033	1.04GlnAsn: 1.04 ± 0.046	2.119GlnPro: 2.119 ± 0.097	2.161GlnGln: 2.161 ± 0.111	2.565GlnArg: 2.565 ± 0.075	2.64GlnSer: 2.64 ± 0.086	2.37GlnThr: 2.37 ± 0.072	2.518GlnVal: 2.518 ± 0.061	0.629GlnTrp: 0.629 ± 0.036	0.971GlnTyr: 0.971 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	5.362ArgAla: 5.362 ± 0.102	0.587ArgCys: 0.587 ± 0.034	3.747ArgAsp: 3.747 ± 0.102	3.318ArgGlu: 3.318 ± 0.08	2.189ArgPhe: 2.189 ± 0.065	4.042ArgGly: 4.042 ± 0.099	1.755ArgHis: 1.755 ± 0.067	3.532ArgIle: 3.532 ± 0.08	2.403ArgLys: 2.403 ± 0.071	5.357ArgLeu: 5.357 ± 0.123	1.853ArgMet: 1.853 ± 0.061	2.053ArgAsn: 2.053 ± 0.065	2.417ArgPro: 2.417 ± 0.072	2.369ArgGln: 2.369 ± 0.077	5.24ArgArg: 5.24 ± 0.132	3.458ArgSer: 3.458 ± 0.076	3.675ArgThr: 3.675 ± 0.084	4.33ArgVal: 4.33 ± 0.088	0.82ArgTrp: 0.82 ± 0.043	1.764ArgTyr: 1.764 ± 0.06	0.005ArgXaa: 0.005 ± 0.004
Ser	8.157SerAla: 8.157 ± 0.151	0.581SerCys: 0.581 ± 0.036	5.113SerAsp: 5.113 ± 0.118	3.118SerGlu: 3.118 ± 0.072	2.028SerPhe: 2.028 ± 0.054	5.825SerGly: 5.825 ± 0.121	1.738SerHis: 1.738 ± 0.055	3.17SerIle: 3.17 ± 0.072	2.223SerLys: 2.223 ± 0.067	5.398SerLeu: 5.398 ± 0.102	1.672SerMet: 1.672 ± 0.058	2.17SerAsn: 2.17 ± 0.067	2.79SerPro: 2.79 ± 0.076	3.007SerGln: 3.007 ± 0.086	3.807SerArg: 3.807 ± 0.093	5.646SerSer: 5.646 ± 0.21	4.631SerThr: 4.631 ± 0.117	5.082SerVal: 5.082 ± 0.111	0.946SerTrp: 0.946 ± 0.04	1.657SerTyr: 1.657 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	7.187ThrAla: 7.187 ± 0.144	0.618ThrCys: 0.618 ± 0.037	4.366ThrAsp: 4.366 ± 0.106	2.698ThrGlu: 2.698 ± 0.071	1.928ThrPhe: 1.928 ± 0.065	5.316ThrGly: 5.316 ± 0.106	1.455ThrHis: 1.455 ± 0.054	3.362ThrIle: 3.362 ± 0.085	2.106ThrLys: 2.106 ± 0.069	5.624ThrLeu: 5.624 ± 0.105	1.485ThrMet: 1.485 ± 0.044	2.116ThrAsn: 2.116 ± 0.064	3.808ThrPro: 3.808 ± 0.088	2.609ThrGln: 2.609 ± 0.093	3.24ThrArg: 3.24 ± 0.085	4.192ThrSer: 4.192 ± 0.106	4.387ThrThr: 4.387 ± 0.123	5.679ThrVal: 5.679 ± 0.142	0.828ThrTrp: 0.828 ± 0.043	1.746ThrTyr: 1.746 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	8.297ValAla: 8.297 ± 0.146	1.037ValCys: 1.037 ± 0.043	5.04ValAsp: 5.04 ± 0.099	4.069ValGlu: 4.069 ± 0.085	2.67ValPhe: 2.67 ± 0.08	5.021ValGly: 5.021 ± 0.095	1.68ValHis: 1.68 ± 0.058	4.085ValIle: 4.085 ± 0.09	2.6ValLys: 2.6 ± 0.071	6.836ValLeu: 6.836 ± 0.112	1.902ValMet: 1.902 ± 0.062	2.414ValAsn: 2.414 ± 0.061	4.031ValPro: 4.031 ± 0.102	2.534ValGln: 2.534 ± 0.062	4.664ValArg: 4.664 ± 0.104	5.241ValSer: 5.241 ± 0.123	5.401ValThr: 5.401 ± 0.119	6.328ValVal: 6.328 ± 0.127	0.982ValTrp: 0.982 ± 0.044	1.769ValTyr: 1.769 ± 0.058	0.002ValXaa: 0.002 ± 0.002
Trp	1.168TrpAla: 1.168 ± 0.047	0.208TrpCys: 0.208 ± 0.019	0.89TrpAsp: 0.89 ± 0.044	0.621TrpGlu: 0.621 ± 0.033	0.501TrpPhe: 0.501 ± 0.031	1.001TrpGly: 1.001 ± 0.042	0.412TrpHis: 0.412 ± 0.025	0.625TrpIle: 0.625 ± 0.03	0.565TrpLys: 0.565 ± 0.035	1.232TrpLeu: 1.232 ± 0.05	0.406TrpMet: 0.406 ± 0.029	0.606TrpAsn: 0.606 ± 0.036	0.487TrpPro: 0.487 ± 0.03	0.587TrpGln: 0.587 ± 0.034	0.932TrpArg: 0.932 ± 0.042	0.909TrpSer: 0.909 ± 0.04	0.735TrpThr: 0.735 ± 0.037	0.863TrpVal: 0.863 ± 0.043	0.292TrpTrp: 0.292 ± 0.025	0.423TrpTyr: 0.423 ± 0.032	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.839TyrAla: 2.839 ± 0.071	0.287TyrCys: 0.287 ± 0.022	1.889TyrAsp: 1.889 ± 0.063	1.447TyrGlu: 1.447 ± 0.048	0.91TyrPhe: 0.91 ± 0.037	2.305TyrGly: 2.305 ± 0.068	0.542TyrHis: 0.542 ± 0.03	0.977TyrIle: 0.977 ± 0.042	0.849TyrLys: 0.849 ± 0.041	2.187TyrLeu: 2.187 ± 0.067	0.604TyrMet: 0.604 ± 0.031	0.79TyrAsn: 0.79 ± 0.035	1.135TyrPro: 1.135 ± 0.038	0.937TyrGln: 0.937 ± 0.048	1.622TyrArg: 1.622 ± 0.046	1.733TyrSer: 1.733 ± 0.065	1.611TyrThr: 1.611 ± 0.053	2.1TyrVal: 2.1 ± 0.065	0.387TyrTrp: 0.387 ± 0.025	0.768TyrTyr: 0.768 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.003XaaAla: 0.003 ± 0.003	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.002XaaGlu: 0.002 ± 0.002	0.002XaaPhe: 0.002 ± 0.002	0.002XaaGly: 0.002 ± 0.002	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.003XaaMet: 0.003 ± 0.003	0.002XaaAsn: 0.002 ± 0.002	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.002XaaArg: 0.002 ± 0.002	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.002XaaVal: 0.002 ± 0.002	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.003XaaXaa: 0.003 ± 0.003

Statistics based on 1732 proteins (640469 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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