Amino acid dipepetide frequency for Flavonifractor plautii ATCC 29863

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.876AlaAla: 13.876 ± 0.158	1.653AlaCys: 1.653 ± 0.04	5.463AlaAsp: 5.463 ± 0.086	7.315AlaGlu: 7.315 ± 0.095	3.564AlaPhe: 3.564 ± 0.058	8.86AlaGly: 8.86 ± 0.097	1.658AlaHis: 1.658 ± 0.039	4.781AlaIle: 4.781 ± 0.071	3.721AlaLys: 3.721 ± 0.064	11.775AlaLeu: 11.775 ± 0.141	2.726AlaMet: 2.726 ± 0.049	2.418AlaAsn: 2.418 ± 0.05	4.102AlaPro: 4.102 ± 0.069	3.593AlaGln: 3.593 ± 0.057	5.971AlaArg: 5.971 ± 0.087	4.506AlaSer: 4.506 ± 0.076	3.683AlaThr: 3.683 ± 0.059	8.792AlaVal: 8.792 ± 0.111	1.094AlaTrp: 1.094 ± 0.03	2.783AlaTyr: 2.783 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.685CysAla: 1.685 ± 0.04	0.331CysCys: 0.331 ± 0.016	0.83CysAsp: 0.83 ± 0.029	0.725CysGlu: 0.725 ± 0.023	0.69CysPhe: 0.69 ± 0.027	1.782CysGly: 1.782 ± 0.047	0.3CysHis: 0.3 ± 0.017	0.797CysIle: 0.797 ± 0.028	0.579CysLys: 0.579 ± 0.022	1.413CysLeu: 1.413 ± 0.033	0.391CysMet: 0.391 ± 0.019	0.401CysAsn: 0.401 ± 0.02	0.912CysPro: 0.912 ± 0.032	0.461CysGln: 0.461 ± 0.019	1.159CysArg: 1.159 ± 0.034	0.887CysSer: 0.887 ± 0.027	0.908CysThr: 0.908 ± 0.029	1.115CysVal: 1.115 ± 0.031	0.191CysTrp: 0.191 ± 0.011	0.591CysTyr: 0.591 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	5.331AspAla: 5.331 ± 0.069	0.885AspCys: 0.885 ± 0.03	2.452AspAsp: 2.452 ± 0.058	3.677AspGlu: 3.677 ± 0.064	2.324AspPhe: 2.324 ± 0.046	5.505AspGly: 5.505 ± 0.084	0.972AspHis: 0.972 ± 0.032	3.136AspIle: 3.136 ± 0.052	2.277AspLys: 2.277 ± 0.051	4.429AspLeu: 4.429 ± 0.062	1.535AspMet: 1.535 ± 0.04	1.555AspAsn: 1.555 ± 0.037	2.424AspPro: 2.424 ± 0.042	1.431AspGln: 1.431 ± 0.04	3.142AspArg: 3.142 ± 0.055	2.579AspSer: 2.579 ± 0.06	3.076AspThr: 3.076 ± 0.053	3.691AspVal: 3.691 ± 0.058	0.785AspTrp: 0.785 ± 0.026	2.29AspTyr: 2.29 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	7.11GluAla: 7.11 ± 0.087	0.719GluCys: 0.719 ± 0.023	3.494GluAsp: 3.494 ± 0.061	5.795GluGlu: 5.795 ± 0.083	1.916GluPhe: 1.916 ± 0.042	5.315GluGly: 5.315 ± 0.074	1.565GluHis: 1.565 ± 0.037	3.383GluIle: 3.383 ± 0.056	3.527GluLys: 3.527 ± 0.061	7.937GluLeu: 7.937 ± 0.105	1.717GluMet: 1.717 ± 0.035	2.349GluAsn: 2.349 ± 0.046	2.632GluPro: 2.632 ± 0.052	3.078GluGln: 3.078 ± 0.057	4.826GluArg: 4.826 ± 0.077	2.747GluSer: 2.747 ± 0.05	3.242GluThr: 3.242 ± 0.063	4.308GluVal: 4.308 ± 0.069	0.705GluTrp: 0.705 ± 0.027	2.137GluTyr: 2.137 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.447PheAla: 3.447 ± 0.067	0.8PheCys: 0.8 ± 0.027	2.134PheAsp: 2.134 ± 0.042	1.863PheGlu: 1.863 ± 0.039	1.624PhePhe: 1.624 ± 0.04	3.02PheGly: 3.02 ± 0.057	0.805PheHis: 0.805 ± 0.026	1.615PheIle: 1.615 ± 0.038	1.061PheLys: 1.061 ± 0.037	4.06PheLeu: 4.06 ± 0.07	0.793PheMet: 0.793 ± 0.029	1.074PheAsn: 1.074 ± 0.03	1.708PhePro: 1.708 ± 0.039	1.452PheGln: 1.452 ± 0.036	2.181PheArg: 2.181 ± 0.044	2.511PheSer: 2.511 ± 0.049	2.358PheThr: 2.358 ± 0.046	2.463PheVal: 2.463 ± 0.048	0.465PheTrp: 0.465 ± 0.021	1.381PheTyr: 1.381 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	7.851GlyAla: 7.851 ± 0.099	1.523GlyCys: 1.523 ± 0.045	4.145GlyAsp: 4.145 ± 0.059	5.706GlyGlu: 5.706 ± 0.08	3.02GlyPhe: 3.02 ± 0.048	7.536GlyGly: 7.536 ± 0.124	1.482GlyHis: 1.482 ± 0.037	4.707GlyIle: 4.707 ± 0.078	4.107GlyLys: 4.107 ± 0.061	8.177GlyLeu: 8.177 ± 0.095	2.591GlyMet: 2.591 ± 0.044	2.409GlyAsn: 2.409 ± 0.052	2.54GlyPro: 2.54 ± 0.056	2.755GlyGln: 2.755 ± 0.051	5.39GlyArg: 5.39 ± 0.083	4.407GlySer: 4.407 ± 0.076	4.87GlyThr: 4.87 ± 0.077	6.536GlyVal: 6.536 ± 0.096	1.137GlyTrp: 1.137 ± 0.033	3.059GlyTyr: 3.059 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	1.458HisAla: 1.458 ± 0.039	0.358HisCys: 0.358 ± 0.017	0.893HisAsp: 0.893 ± 0.028	0.915HisGlu: 0.915 ± 0.03	0.805HisPhe: 0.805 ± 0.031	1.622HisGly: 1.622 ± 0.043	0.378HisHis: 0.378 ± 0.021	1.238HisIle: 1.238 ± 0.033	0.689HisLys: 0.689 ± 0.026	1.829HisLeu: 1.829 ± 0.041	0.499HisMet: 0.499 ± 0.021	0.599HisAsn: 0.599 ± 0.02	1.174HisPro: 1.174 ± 0.038	0.562HisGln: 0.562 ± 0.024	1.166HisArg: 1.166 ± 0.036	0.911HisSer: 0.911 ± 0.03	1.15HisThr: 1.15 ± 0.031	1.158HisVal: 1.158 ± 0.034	0.253HisTrp: 0.253 ± 0.015	0.688HisTyr: 0.688 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	4.757IleAla: 4.757 ± 0.068	0.895IleCys: 0.895 ± 0.028	2.82IleAsp: 2.82 ± 0.049	2.783IleGlu: 2.783 ± 0.054	1.851IlePhe: 1.851 ± 0.047	4.017IleGly: 4.017 ± 0.059	1.053IleHis: 1.053 ± 0.028	2.646IleIle: 2.646 ± 0.062	1.837IleLys: 1.837 ± 0.049	5.415IleLeu: 5.415 ± 0.07	1.141IleMet: 1.141 ± 0.03	1.67IleAsn: 1.67 ± 0.043	2.873IlePro: 2.873 ± 0.053	1.963IleGln: 1.963 ± 0.049	3.159IleArg: 3.159 ± 0.062	3.083IleSer: 3.083 ± 0.064	3.303IleThr: 3.303 ± 0.069	3.472IleVal: 3.472 ± 0.062	0.481IleTrp: 0.481 ± 0.024	1.635IleTyr: 1.635 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.101LysAla: 4.101 ± 0.065	0.472LysCys: 0.472 ± 0.023	2.044LysAsp: 2.044 ± 0.05	3.258LysGlu: 3.258 ± 0.057	1.106LysPhe: 1.106 ± 0.036	3.164LysGly: 3.164 ± 0.057	0.683LysHis: 0.683 ± 0.022	2.102LysIle: 2.102 ± 0.046	2.72LysLys: 2.72 ± 0.061	4.097LysLeu: 4.097 ± 0.064	1.186LysMet: 1.186 ± 0.032	1.602LysAsn: 1.602 ± 0.038	1.755LysPro: 1.755 ± 0.044	1.509LysGln: 1.509 ± 0.039	2.623LysArg: 2.623 ± 0.048	2.165LysSer: 2.165 ± 0.046	2.398LysThr: 2.398 ± 0.048	2.747LysVal: 2.747 ± 0.056	0.433LysTrp: 0.433 ± 0.021	1.53LysTyr: 1.53 ± 0.034	0.0LysXaa: 0.0 ± 0.0
Leu	10.789LeuAla: 10.789 ± 0.126	2.05LeuCys: 2.05 ± 0.046	5.931LeuAsp: 5.931 ± 0.081	7.135LeuGlu: 7.135 ± 0.077	4.019LeuPhe: 4.019 ± 0.069	7.711LeuGly: 7.711 ± 0.111	1.814LeuHis: 1.814 ± 0.041	4.476LeuIle: 4.476 ± 0.075	3.826LeuLys: 3.826 ± 0.064	11.437LeuLeu: 11.437 ± 0.154	2.533LeuMet: 2.533 ± 0.047	3.183LeuAsn: 3.183 ± 0.053	5.219LeuPro: 5.219 ± 0.071	2.793LeuGln: 2.793 ± 0.046	6.578LeuArg: 6.578 ± 0.095	6.893LeuSer: 6.893 ± 0.087	6.489LeuThr: 6.489 ± 0.082	6.614LeuVal: 6.614 ± 0.076	1.161LeuTrp: 1.161 ± 0.039	3.287LeuTyr: 3.287 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.733MetAla: 2.733 ± 0.051	0.314MetCys: 0.314 ± 0.017	1.713MetAsp: 1.713 ± 0.041	2.228MetGlu: 2.228 ± 0.04	0.739MetPhe: 0.739 ± 0.024	2.218MetGly: 2.218 ± 0.047	0.384MetHis: 0.384 ± 0.022	1.164MetIle: 1.164 ± 0.032	1.544MetLys: 1.544 ± 0.038	2.556MetLeu: 2.556 ± 0.048	0.683MetMet: 0.683 ± 0.026	1.021MetAsn: 1.021 ± 0.033	1.157MetPro: 1.157 ± 0.034	0.756MetGln: 0.756 ± 0.027	1.436MetArg: 1.436 ± 0.036	1.502MetSer: 1.502 ± 0.033	1.638MetThr: 1.638 ± 0.04	1.823MetVal: 1.823 ± 0.042	0.21MetTrp: 0.21 ± 0.016	0.572MetTyr: 0.572 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.806AsnAla: 2.806 ± 0.055	0.492AsnCys: 0.492 ± 0.024	1.42AsnAsp: 1.42 ± 0.04	1.67AsnGlu: 1.67 ± 0.044	1.061AsnPhe: 1.061 ± 0.028	2.879AsnGly: 2.879 ± 0.065	0.599AsnHis: 0.599 ± 0.024	1.826AsnIle: 1.826 ± 0.042	1.166AsnLys: 1.166 ± 0.037	3.123AsnLeu: 3.123 ± 0.054	0.84AsnMet: 0.84 ± 0.024	0.994AsnAsn: 0.994 ± 0.036	1.874AsnPro: 1.874 ± 0.04	1.09AsnGln: 1.09 ± 0.032	1.908AsnArg: 1.908 ± 0.04	1.52AsnSer: 1.52 ± 0.043	1.724AsnThr: 1.724 ± 0.047	2.103AsnVal: 2.103 ± 0.046	0.383AsnTrp: 0.383 ± 0.018	1.1AsnTyr: 1.1 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.14ProAla: 5.14 ± 0.079	0.694ProCys: 0.694 ± 0.022	2.927ProAsp: 2.927 ± 0.051	4.298ProGlu: 4.298 ± 0.07	1.687ProPhe: 1.687 ± 0.04	3.812ProGly: 3.812 ± 0.06	0.85ProHis: 0.85 ± 0.029	2.095ProIle: 2.095 ± 0.048	1.593ProLys: 1.593 ± 0.036	4.186ProLeu: 4.186 ± 0.062	1.17ProMet: 1.17 ± 0.032	1.247ProAsn: 1.247 ± 0.03	2.037ProPro: 2.037 ± 0.048	1.5ProGln: 1.5 ± 0.038	2.153ProArg: 2.153 ± 0.054	2.316ProSer: 2.316 ± 0.049	2.144ProThr: 2.144 ± 0.047	3.688ProVal: 3.688 ± 0.057	0.535ProTrp: 0.535 ± 0.022	1.509ProTyr: 1.509 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.733GlnAla: 3.733 ± 0.056	0.385GlnCys: 0.385 ± 0.017	1.525GlnAsp: 1.525 ± 0.038	2.462GlnGlu: 2.462 ± 0.043	1.141GlnPhe: 1.141 ± 0.029	2.526GlnGly: 2.526 ± 0.053	0.537GlnHis: 0.537 ± 0.021	1.754GlnIle: 1.754 ± 0.043	1.836GlnLys: 1.836 ± 0.043	3.05GlnLeu: 3.05 ± 0.053	1.127GlnMet: 1.127 ± 0.032	1.242GlnAsn: 1.242 ± 0.035	1.402GlnPro: 1.402 ± 0.038	1.295GlnGln: 1.295 ± 0.039	2.137GlnArg: 2.137 ± 0.05	1.751GlnSer: 1.751 ± 0.041	1.868GlnThr: 1.868 ± 0.044	2.485GlnVal: 2.485 ± 0.047	0.409GlnTrp: 0.409 ± 0.018	1.212GlnTyr: 1.212 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	6.009ArgAla: 6.009 ± 0.081	0.924ArgCys: 0.924 ± 0.033	3.037ArgAsp: 3.037 ± 0.057	4.606ArgGlu: 4.606 ± 0.074	2.452ArgPhe: 2.452 ± 0.041	4.185ArgGly: 4.185 ± 0.069	1.127ArgHis: 1.127 ± 0.036	3.192ArgIle: 3.192 ± 0.058	2.662ArgLys: 2.662 ± 0.055	6.616ArgLeu: 6.616 ± 0.097	1.791ArgMet: 1.791 ± 0.042	1.708ArgAsn: 1.708 ± 0.04	2.94ArgPro: 2.94 ± 0.057	2.443ArgGln: 2.443 ± 0.054	5.203ArgArg: 5.203 ± 0.092	2.923ArgSer: 2.923 ± 0.055	3.106ArgThr: 3.106 ± 0.046	3.959ArgVal: 3.959 ± 0.063	0.817ArgTrp: 0.817 ± 0.029	2.206ArgTyr: 2.206 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	5.295SerAla: 5.295 ± 0.082	0.754SerCys: 0.754 ± 0.028	2.726SerAsp: 2.726 ± 0.054	2.838SerGlu: 2.838 ± 0.05	2.207SerPhe: 2.207 ± 0.049	5.455SerGly: 5.455 ± 0.081	1.026SerHis: 1.026 ± 0.032	2.965SerIle: 2.965 ± 0.055	1.991SerLys: 1.991 ± 0.045	5.32SerLeu: 5.32 ± 0.067	1.502SerMet: 1.502 ± 0.034	1.554SerAsn: 1.554 ± 0.047	2.53SerPro: 2.53 ± 0.048	1.676SerGln: 1.676 ± 0.046	3.147SerArg: 3.147 ± 0.052	3.01SerSer: 3.01 ± 0.057	2.802SerThr: 2.802 ± 0.058	3.939SerVal: 3.939 ± 0.063	0.539SerTrp: 0.539 ± 0.023	1.918SerTyr: 1.918 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.959ThrAla: 5.959 ± 0.082	0.744ThrCys: 0.744 ± 0.028	2.943ThrAsp: 2.943 ± 0.06	3.182ThrGlu: 3.182 ± 0.056	2.009ThrPhe: 2.009 ± 0.046	5.415ThrGly: 5.415 ± 0.071	1.003ThrHis: 1.003 ± 0.032	2.994ThrIle: 2.994 ± 0.063	1.776ThrLys: 1.776 ± 0.043	5.784ThrLeu: 5.784 ± 0.075	1.307ThrMet: 1.307 ± 0.033	1.554ThrAsn: 1.554 ± 0.044	3.047ThrPro: 3.047 ± 0.052	1.627ThrGln: 1.627 ± 0.04	2.642ThrArg: 2.642 ± 0.046	2.605ThrSer: 2.605 ± 0.058	2.747ThrThr: 2.747 ± 0.065	5.093ThrVal: 5.093 ± 0.079	0.62ThrTrp: 0.62 ± 0.024	1.714ThrTyr: 1.714 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	6.235ValAla: 6.235 ± 0.087	1.405ValCys: 1.405 ± 0.034	4.245ValAsp: 4.245 ± 0.071	5.052ValGlu: 5.052 ± 0.069	2.8ValPhe: 2.8 ± 0.055	5.227ValGly: 5.227 ± 0.076	1.146ValHis: 1.146 ± 0.035	3.719ValIle: 3.719 ± 0.073	3.086ValLys: 3.086 ± 0.057	8.008ValLeu: 8.008 ± 0.09	1.812ValMet: 1.812 ± 0.039	2.389ValAsn: 2.389 ± 0.048	3.29ValPro: 3.29 ± 0.054	2.071ValGln: 2.071 ± 0.044	4.165ValArg: 4.165 ± 0.069	4.518ValSer: 4.518 ± 0.067	4.509ValThr: 4.509 ± 0.087	5.509ValVal: 5.509 ± 0.09	0.816ValTrp: 0.816 ± 0.029	2.311ValTyr: 2.311 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	1.083TrpAla: 1.083 ± 0.037	0.202TrpCys: 0.202 ± 0.013	0.651TrpAsp: 0.651 ± 0.028	0.825TrpGlu: 0.825 ± 0.031	0.468TrpPhe: 0.468 ± 0.022	0.909TrpGly: 0.909 ± 0.027	0.231TrpHis: 0.231 ± 0.013	0.452TrpIle: 0.452 ± 0.021	0.525TrpLys: 0.525 ± 0.021	1.275TrpLeu: 1.275 ± 0.034	0.331TrpMet: 0.331 ± 0.015	0.443TrpAsn: 0.443 ± 0.019	0.448TrpPro: 0.448 ± 0.02	0.452TrpGln: 0.452 ± 0.021	0.748TrpArg: 0.748 ± 0.032	0.629TrpSer: 0.629 ± 0.024	0.574TrpThr: 0.574 ± 0.023	0.676TrpVal: 0.676 ± 0.028	0.155TrpTrp: 0.155 ± 0.013	0.472TrpTyr: 0.472 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.939TyrAla: 2.939 ± 0.057	0.546TyrCys: 0.546 ± 0.023	2.103TyrAsp: 2.103 ± 0.045	2.167TyrGlu: 2.167 ± 0.049	1.332TyrPhe: 1.332 ± 0.036	2.792TyrGly: 2.792 ± 0.05	0.733TyrHis: 0.733 ± 0.025	1.81TyrIle: 1.81 ± 0.047	1.172TyrLys: 1.172 ± 0.037	3.452TyrLeu: 3.452 ± 0.057	0.715TyrMet: 0.715 ± 0.026	1.164TyrAsn: 1.164 ± 0.033	1.52TyrPro: 1.52 ± 0.035	1.371TyrGln: 1.371 ± 0.034	2.172TyrArg: 2.172 ± 0.051	1.73TyrSer: 1.73 ± 0.042	2.174TyrThr: 2.174 ± 0.054	2.143TyrVal: 2.143 ± 0.049	0.36TyrTrp: 0.36 ± 0.019	1.378TyrTyr: 1.378 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4278 proteins (1149482 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---