Amino acid dipepetide frequency for Thiocapsa marina 5811

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.529AlaAla: 14.529 ± 0.131	1.273AlaCys: 1.273 ± 0.024	6.805AlaAsp: 6.805 ± 0.063	7.918AlaGlu: 7.918 ± 0.096	3.969AlaPhe: 3.969 ± 0.043	9.527AlaGly: 9.527 ± 0.093	2.245AlaHis: 2.245 ± 0.042	5.493AlaIle: 5.493 ± 0.061	2.858AlaLys: 2.858 ± 0.059	13.785AlaLeu: 13.785 ± 0.132	2.906AlaMet: 2.906 ± 0.048	2.404AlaAsn: 2.404 ± 0.041	5.472AlaPro: 5.472 ± 0.085	3.684AlaGln: 3.684 ± 0.053	9.21AlaArg: 9.21 ± 0.09	5.787AlaSer: 5.787 ± 0.067	5.309AlaThr: 5.309 ± 0.065	8.388AlaVal: 8.388 ± 0.081	1.649AlaTrp: 1.649 ± 0.036	2.497AlaTyr: 2.497 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	1.133CysAla: 1.133 ± 0.031	0.153CysCys: 0.153 ± 0.011	0.561CysAsp: 0.561 ± 0.023	0.597CysGlu: 0.597 ± 0.021	0.333CysPhe: 0.333 ± 0.014	1.046CysGly: 1.046 ± 0.025	0.337CysHis: 0.337 ± 0.02	0.408CysIle: 0.408 ± 0.017	0.206CysLys: 0.206 ± 0.01	0.99CysLeu: 0.99 ± 0.026	0.165CysMet: 0.165 ± 0.01	0.25CysAsn: 0.25 ± 0.013	0.656CysPro: 0.656 ± 0.024	0.226CysGln: 0.226 ± 0.013	0.92CysArg: 0.92 ± 0.027	0.552CysSer: 0.552 ± 0.017	0.498CysThr: 0.498 ± 0.02	0.713CysVal: 0.713 ± 0.023	0.13CysTrp: 0.13 ± 0.008	0.23CysTyr: 0.23 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.455AspAla: 7.455 ± 0.084	0.612AspCys: 0.612 ± 0.02	3.349AspAsp: 3.349 ± 0.057	3.507AspGlu: 3.507 ± 0.056	2.188AspPhe: 2.188 ± 0.042	5.096AspGly: 5.096 ± 0.065	1.223AspHis: 1.223 ± 0.031	2.623AspIle: 2.623 ± 0.046	1.251AspLys: 1.251 ± 0.026	7.342AspLeu: 7.342 ± 0.082	1.135AspMet: 1.135 ± 0.03	1.234AspAsn: 1.234 ± 0.03	4.265AspPro: 4.265 ± 0.06	1.952AspGln: 1.952 ± 0.035	5.111AspArg: 5.111 ± 0.06	2.54AspSer: 2.54 ± 0.047	2.689AspThr: 2.689 ± 0.044	3.792AspVal: 3.792 ± 0.058	1.25AspTrp: 1.25 ± 0.029	1.708AspTyr: 1.708 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.916GluAla: 6.916 ± 0.087	0.453GluCys: 0.453 ± 0.018	3.156GluAsp: 3.156 ± 0.049	3.376GluGlu: 3.376 ± 0.054	1.49GluPhe: 1.49 ± 0.03	4.416GluGly: 4.416 ± 0.053	1.58GluHis: 1.58 ± 0.029	3.655GluIle: 3.655 ± 0.054	1.638GluLys: 1.638 ± 0.038	6.254GluLeu: 6.254 ± 0.071	1.363GluMet: 1.363 ± 0.033	1.384GluAsn: 1.384 ± 0.03	3.435GluPro: 3.435 ± 0.046	3.005GluGln: 3.005 ± 0.048	6.376GluArg: 6.376 ± 0.083	3.313GluSer: 3.313 ± 0.053	3.903GluThr: 3.903 ± 0.054	4.295GluVal: 4.295 ± 0.062	0.74GluTrp: 0.74 ± 0.022	1.139GluTyr: 1.139 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.897PheAla: 3.897 ± 0.052	0.405PheCys: 0.405 ± 0.015	2.548PheAsp: 2.548 ± 0.04	2.269PheGlu: 2.269 ± 0.037	1.369PhePhe: 1.369 ± 0.028	3.245PheGly: 3.245 ± 0.05	0.703PheHis: 0.703 ± 0.023	1.499PheIle: 1.499 ± 0.032	0.953PheLys: 0.953 ± 0.027	3.411PheLeu: 3.411 ± 0.061	0.686PheMet: 0.686 ± 0.022	0.951PheAsn: 0.951 ± 0.025	1.612PhePro: 1.612 ± 0.031	0.983PheGln: 0.983 ± 0.024	2.331PheArg: 2.331 ± 0.041	2.036PheSer: 2.036 ± 0.039	1.701PheThr: 1.701 ± 0.037	2.676PheVal: 2.676 ± 0.04	0.519PheTrp: 0.519 ± 0.019	0.927PheTyr: 0.927 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	8.362GlyAla: 8.362 ± 0.089	1.064GlyCys: 1.064 ± 0.031	4.606GlyAsp: 4.606 ± 0.06	5.023GlyGlu: 5.023 ± 0.057	3.432GlyPhe: 3.432 ± 0.041	6.398GlyGly: 6.398 ± 0.088	1.936GlyHis: 1.936 ± 0.039	4.535GlyIle: 4.535 ± 0.057	2.391GlyLys: 2.391 ± 0.046	9.22GlyLeu: 9.22 ± 0.098	2.067GlyMet: 2.067 ± 0.038	1.901GlyAsn: 1.901 ± 0.042	3.454GlyPro: 3.454 ± 0.049	2.686GlyGln: 2.686 ± 0.048	6.53GlyArg: 6.53 ± 0.071	4.536GlySer: 4.536 ± 0.063	4.229GlyThr: 4.229 ± 0.054	5.983GlyVal: 5.983 ± 0.069	1.405GlyTrp: 1.405 ± 0.03	2.34GlyTyr: 2.34 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.422HisAla: 2.422 ± 0.043	0.277HisCys: 0.277 ± 0.014	1.142HisAsp: 1.142 ± 0.029	1.131HisGlu: 1.131 ± 0.025	0.84HisPhe: 0.84 ± 0.021	1.89HisGly: 1.89 ± 0.033	0.603HisHis: 0.603 ± 0.018	0.806HisIle: 0.806 ± 0.023	0.444HisLys: 0.444 ± 0.017	2.639HisLeu: 2.639 ± 0.045	0.376HisMet: 0.376 ± 0.017	0.466HisAsn: 0.466 ± 0.018	1.717HisPro: 1.717 ± 0.033	0.705HisGln: 0.705 ± 0.019	1.963HisArg: 1.963 ± 0.039	0.946HisSer: 0.946 ± 0.028	0.895HisThr: 0.895 ± 0.026	1.364HisVal: 1.364 ± 0.03	0.442HisTrp: 0.442 ± 0.018	0.621HisTyr: 0.621 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.402IleAla: 6.402 ± 0.068	0.461IleCys: 0.461 ± 0.018	3.507IleAsp: 3.507 ± 0.05	3.761IleGlu: 3.761 ± 0.054	1.417IlePhe: 1.417 ± 0.035	4.675IleGly: 4.675 ± 0.06	1.085IleHis: 1.085 ± 0.026	1.827IleIle: 1.827 ± 0.041	1.324IleLys: 1.324 ± 0.035	5.087IleLeu: 5.087 ± 0.062	0.774IleMet: 0.774 ± 0.025	1.237IleAsn: 1.237 ± 0.028	2.803IlePro: 2.803 ± 0.05	1.522IleGln: 1.522 ± 0.03	3.765IleArg: 3.765 ± 0.054	2.275IleSer: 2.275 ± 0.039	2.196IleThr: 2.196 ± 0.042	3.161IleVal: 3.161 ± 0.049	0.53IleTrp: 0.53 ± 0.021	1.061IleTyr: 1.061 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.99LysAla: 2.99 ± 0.055	0.176LysCys: 0.176 ± 0.012	1.448LysAsp: 1.448 ± 0.034	1.385LysGlu: 1.385 ± 0.037	0.553LysPhe: 0.553 ± 0.022	2.072LysGly: 2.072 ± 0.044	0.586LysHis: 0.586 ± 0.021	1.24LysIle: 1.24 ± 0.03	0.841LysLys: 0.841 ± 0.03	2.465LysLeu: 2.465 ± 0.047	0.49LysMet: 0.49 ± 0.017	0.642LysAsn: 0.642 ± 0.022	1.581LysPro: 1.581 ± 0.034	1.024LysGln: 1.024 ± 0.027	2.26LysArg: 2.26 ± 0.045	1.354LysSer: 1.354 ± 0.038	1.669LysThr: 1.669 ± 0.037	1.775LysVal: 1.775 ± 0.038	0.269LysTrp: 0.269 ± 0.012	0.51LysTyr: 0.51 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.146LeuAla: 14.146 ± 0.114	1.046LeuCys: 1.046 ± 0.028	7.465LeuAsp: 7.465 ± 0.077	6.726LeuGlu: 6.726 ± 0.08	3.965LeuPhe: 3.965 ± 0.061	9.017LeuGly: 9.017 ± 0.099	2.201LeuHis: 2.201 ± 0.042	5.659LeuIle: 5.659 ± 0.068	3.045LeuLys: 3.045 ± 0.053	11.926LeuLeu: 11.926 ± 0.125	2.529LeuMet: 2.529 ± 0.045	2.428LeuAsn: 2.428 ± 0.037	6.036LeuPro: 6.036 ± 0.071	3.145LeuGln: 3.145 ± 0.05	8.443LeuArg: 8.443 ± 0.095	6.283LeuSer: 6.283 ± 0.072	5.52LeuThr: 5.52 ± 0.07	8.406LeuVal: 8.406 ± 0.087	1.37LeuTrp: 1.37 ± 0.035	2.41LeuTyr: 2.41 ± 0.048	0.001LeuXaa: 0.001 ± 0.001
Met	2.393MetAla: 2.393 ± 0.041	0.145MetCys: 0.145 ± 0.01	1.259MetAsp: 1.259 ± 0.027	1.097MetGlu: 1.097 ± 0.029	0.545MetPhe: 0.545 ± 0.02	1.587MetGly: 1.587 ± 0.034	0.462MetHis: 0.462 ± 0.019	1.169MetIle: 1.169 ± 0.029	0.71MetLys: 0.71 ± 0.022	2.372MetLeu: 2.372 ± 0.041	0.491MetMet: 0.491 ± 0.02	0.647MetAsn: 0.647 ± 0.02	1.469MetPro: 1.469 ± 0.031	0.843MetGln: 0.843 ± 0.023	1.755MetArg: 1.755 ± 0.034	1.519MetSer: 1.519 ± 0.034	1.554MetThr: 1.554 ± 0.034	1.438MetVal: 1.438 ± 0.035	0.163MetTrp: 0.163 ± 0.01	0.311MetTyr: 0.311 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.686AsnAla: 2.686 ± 0.043	0.245AsnCys: 0.245 ± 0.014	1.239AsnAsp: 1.239 ± 0.029	1.131AsnGlu: 1.131 ± 0.032	0.691AsnPhe: 0.691 ± 0.021	1.933AsnGly: 1.933 ± 0.036	0.508AsnHis: 0.508 ± 0.019	1.023AsnIle: 1.023 ± 0.024	0.518AsnLys: 0.518 ± 0.019	2.783AsnLeu: 2.783 ± 0.05	0.432AsnMet: 0.432 ± 0.019	0.582AsnAsn: 0.582 ± 0.022	1.874AsnPro: 1.874 ± 0.04	0.834AsnGln: 0.834 ± 0.023	1.992AsnArg: 1.992 ± 0.034	0.98AsnSer: 0.98 ± 0.025	1.085AsnThr: 1.085 ± 0.029	1.401AsnVal: 1.401 ± 0.029	0.319AsnTrp: 0.319 ± 0.015	0.599AsnTyr: 0.599 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	6.205ProAla: 6.205 ± 0.097	0.51ProCys: 0.51 ± 0.019	4.136ProAsp: 4.136 ± 0.053	4.462ProGlu: 4.462 ± 0.056	1.912ProPhe: 1.912 ± 0.036	4.969ProGly: 4.969 ± 0.072	1.015ProHis: 1.015 ± 0.026	2.495ProIle: 2.495 ± 0.038	1.382ProLys: 1.382 ± 0.031	5.299ProLeu: 5.299 ± 0.065	1.288ProMet: 1.288 ± 0.028	1.317ProAsn: 1.317 ± 0.031	3.096ProPro: 3.096 ± 0.058	1.65ProGln: 1.65 ± 0.035	3.5ProArg: 3.5 ± 0.053	3.247ProSer: 3.247 ± 0.055	2.819ProThr: 2.819 ± 0.045	4.3ProVal: 4.3 ± 0.063	0.852ProTrp: 0.852 ± 0.025	1.212ProTyr: 1.212 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.235GlnAla: 4.235 ± 0.061	0.269GlnCys: 0.269 ± 0.014	1.67GlnAsp: 1.67 ± 0.031	1.655GlnGlu: 1.655 ± 0.036	0.92GlnPhe: 0.92 ± 0.027	2.713GlnGly: 2.713 ± 0.041	0.71GlnHis: 0.71 ± 0.021	1.744GlnIle: 1.744 ± 0.031	0.715GlnLys: 0.715 ± 0.024	3.179GlnLeu: 3.179 ± 0.053	0.667GlnMet: 0.667 ± 0.022	0.631GlnAsn: 0.631 ± 0.021	1.853GlnPro: 1.853 ± 0.036	1.269GlnGln: 1.269 ± 0.03	3.007GlnArg: 3.007 ± 0.049	1.784GlnSer: 1.784 ± 0.036	1.906GlnThr: 1.906 ± 0.035	2.733GlnVal: 2.733 ± 0.048	0.445GlnTrp: 0.445 ± 0.019	0.631GlnTyr: 0.631 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	8.327ArgAla: 8.327 ± 0.094	0.795ArgCys: 0.795 ± 0.024	4.811ArgAsp: 4.811 ± 0.066	5.183ArgGlu: 5.183 ± 0.058	3.418ArgPhe: 3.418 ± 0.049	5.186ArgGly: 5.186 ± 0.063	2.053ArgHis: 2.053 ± 0.041	4.748ArgIle: 4.748 ± 0.059	1.888ArgLys: 1.888 ± 0.041	10.356ArgLeu: 10.356 ± 0.107	1.945ArgMet: 1.945 ± 0.036	1.769ArgAsn: 1.769 ± 0.031	4.048ArgPro: 4.048 ± 0.06	2.572ArgGln: 2.572 ± 0.045	7.251ArgArg: 7.251 ± 0.08	4.048ArgSer: 4.048 ± 0.06	3.662ArgThr: 3.662 ± 0.058	5.869ArgVal: 5.869 ± 0.071	1.322ArgTrp: 1.322 ± 0.027	2.22ArgTyr: 2.22 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	6.165SerAla: 6.165 ± 0.065	0.499SerCys: 0.499 ± 0.02	3.183SerAsp: 3.183 ± 0.048	3.205SerGlu: 3.205 ± 0.051	1.87SerPhe: 1.87 ± 0.037	5.16SerGly: 5.16 ± 0.064	1.081SerHis: 1.081 ± 0.025	2.485SerIle: 2.485 ± 0.039	1.313SerLys: 1.313 ± 0.031	5.508SerLeu: 5.508 ± 0.061	1.254SerMet: 1.254 ± 0.03	1.21SerAsn: 1.21 ± 0.034	3.034SerPro: 3.034 ± 0.046	1.515SerGln: 1.515 ± 0.031	4.026SerArg: 4.026 ± 0.058	2.821SerSer: 2.821 ± 0.047	2.699SerThr: 2.699 ± 0.046	3.822SerVal: 3.822 ± 0.05	0.734SerTrp: 0.734 ± 0.023	1.134SerTyr: 1.134 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	5.619ThrAla: 5.619 ± 0.063	0.493ThrCys: 0.493 ± 0.019	3.014ThrAsp: 3.014 ± 0.044	2.835ThrGlu: 2.835 ± 0.045	1.744ThrPhe: 1.744 ± 0.039	4.734ThrGly: 4.734 ± 0.071	1.081ThrHis: 1.081 ± 0.029	2.225ThrIle: 2.225 ± 0.042	1.093ThrLys: 1.093 ± 0.03	6.427ThrLeu: 6.427 ± 0.077	0.932ThrMet: 0.932 ± 0.025	1.086ThrAsn: 1.086 ± 0.027	3.498ThrPro: 3.498 ± 0.051	1.548ThrGln: 1.548 ± 0.035	3.871ThrArg: 3.871 ± 0.051	2.542ThrSer: 2.542 ± 0.042	2.533ThrThr: 2.533 ± 0.041	3.42ThrVal: 3.42 ± 0.05	0.708ThrTrp: 0.708 ± 0.021	1.13ThrTyr: 1.13 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	8.232ValAla: 8.232 ± 0.085	0.745ValCys: 0.745 ± 0.024	4.349ValAsp: 4.349 ± 0.053	4.709ValGlu: 4.709 ± 0.064	2.625ValPhe: 2.625 ± 0.044	5.53ValGly: 5.53 ± 0.071	1.415ValHis: 1.415 ± 0.036	3.598ValIle: 3.598 ± 0.046	1.887ValLys: 1.887 ± 0.041	7.96ValLeu: 7.96 ± 0.078	1.663ValMet: 1.663 ± 0.029	1.697ValAsn: 1.697 ± 0.036	3.694ValPro: 3.694 ± 0.051	2.166ValGln: 2.166 ± 0.04	5.377ValArg: 5.377 ± 0.067	3.952ValSer: 3.952 ± 0.053	3.902ValThr: 3.902 ± 0.05	5.681ValVal: 5.681 ± 0.08	0.969ValTrp: 0.969 ± 0.026	1.671ValTyr: 1.671 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.177TrpAla: 1.177 ± 0.03	0.184TrpCys: 0.184 ± 0.011	0.737TrpAsp: 0.737 ± 0.022	0.711TrpGlu: 0.711 ± 0.022	0.545TrpPhe: 0.545 ± 0.019	0.928TrpGly: 0.928 ± 0.025	0.36TrpHis: 0.36 ± 0.016	0.798TrpIle: 0.798 ± 0.022	0.376TrpLys: 0.376 ± 0.015	1.922TrpLeu: 1.922 ± 0.039	0.387TrpMet: 0.387 ± 0.016	0.438TrpAsn: 0.438 ± 0.018	0.736TrpPro: 0.736 ± 0.022	0.592TrpGln: 0.592 ± 0.02	1.246TrpArg: 1.246 ± 0.03	0.96TrpSer: 0.96 ± 0.027	0.769TrpThr: 0.769 ± 0.025	1.022TrpVal: 1.022 ± 0.024	0.242TrpTrp: 0.242 ± 0.014	0.342TrpTyr: 0.342 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.418TyrAla: 2.418 ± 0.041	0.296TyrCys: 0.296 ± 0.013	1.337TyrAsp: 1.337 ± 0.032	1.205TyrGlu: 1.205 ± 0.027	0.893TyrPhe: 0.893 ± 0.028	1.977TyrGly: 1.977 ± 0.041	0.504TyrHis: 0.504 ± 0.019	0.839TyrIle: 0.839 ± 0.024	0.499TyrLys: 0.499 ± 0.018	2.842TyrLeu: 2.842 ± 0.049	0.378TyrMet: 0.378 ± 0.016	0.579TyrAsn: 0.579 ± 0.02	1.331TyrPro: 1.331 ± 0.031	0.818TyrGln: 0.818 ± 0.027	2.536TyrArg: 2.536 ± 0.041	1.245TyrSer: 1.245 ± 0.034	0.996TyrThr: 0.996 ± 0.028	1.582TyrVal: 1.582 ± 0.034	0.415TyrTrp: 0.415 ± 0.017	0.614TyrTyr: 0.614 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.001	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4915 proteins (1589608 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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