Amino acid dipepetide frequency for Ancient caribou feces associated virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.597AlaAla: 1.597 ± 0.922
1.597AlaCys: 1.597 ± 0.922
6.39AlaAsp: 6.39 ± 1.355
3.195AlaGlu: 3.195 ± 1.843
1.597AlaPhe: 1.597 ± 1.409
4.792AlaGly: 4.792 ± 1.897
0.0AlaHis: 0.0 ± 0.0
7.987AlaIle: 7.987 ± 2.385
7.987AlaLys: 7.987 ± 2.385
7.987AlaLeu: 7.987 ± 2.277
0.0AlaMet: 0.0 ± 0.91
3.195AlaAsn: 3.195 ± 0.488
0.0AlaPro: 0.0 ± 0.0
1.597AlaGln: 1.597 ± 0.922
3.195AlaArg: 3.195 ± 1.843
3.195AlaSer: 3.195 ± 0.488
6.39AlaThr: 6.39 ± 1.355
3.195AlaVal: 3.195 ± 2.819
1.597AlaTrp: 1.597 ± 0.922
3.195AlaTyr: 3.195 ± 2.819
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.597CysAsp: 1.597 ± 0.922
0.0CysGlu: 0.0 ± 0.0
1.597CysPhe: 1.597 ± 0.922
1.597CysGly: 1.597 ± 0.922
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.597CysGln: 1.597 ± 0.922
1.597CysArg: 1.597 ± 0.922
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.597CysVal: 1.597 ± 0.922
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.195AspAla: 3.195 ± 0.488
0.0AspCys: 0.0 ± 0.0
6.39AspAsp: 6.39 ± 1.355
1.597AspGlu: 1.597 ± 1.409
4.792AspPhe: 4.792 ± 2.765
3.195AspGly: 3.195 ± 0.488
4.792AspHis: 4.792 ± 0.434
1.597AspIle: 1.597 ± 1.409
4.792AspLys: 4.792 ± 0.434
1.597AspLeu: 1.597 ± 0.922
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
1.597AspPro: 1.597 ± 1.409
3.195AspGln: 3.195 ± 0.488
3.195AspArg: 3.195 ± 1.843
6.39AspSer: 6.39 ± 3.686
1.597AspThr: 1.597 ± 0.922
9.585AspVal: 9.585 ± 1.463
1.597AspTrp: 1.597 ± 0.922
3.195AspTyr: 3.195 ± 1.843
0.0AspXaa: 0.0 ± 0.0
Glu
4.792GluAla: 4.792 ± 0.434
0.0GluCys: 0.0 ± 0.0
3.195GluAsp: 3.195 ± 1.843
11.182GluGlu: 11.182 ± 1.789
3.195GluPhe: 3.195 ± 1.843
1.597GluGly: 1.597 ± 1.409
3.195GluHis: 3.195 ± 0.488
1.597GluIle: 1.597 ± 0.922
1.597GluLys: 1.597 ± 0.922
0.0GluLeu: 0.0 ± 0.0
1.597GluMet: 1.597 ± 0.739
1.597GluAsn: 1.597 ± 1.409
4.792GluPro: 4.792 ± 2.765
1.597GluGln: 1.597 ± 0.922
1.597GluArg: 1.597 ± 0.922
4.792GluSer: 4.792 ± 1.897
3.195GluThr: 3.195 ± 2.819
1.597GluVal: 1.597 ± 0.922
0.0GluTrp: 0.0 ± 0.0
3.195GluTyr: 3.195 ± 0.488
0.0GluXaa: 0.0 ± 0.0
Phe
4.792PheAla: 4.792 ± 1.897
0.0PheCys: 0.0 ± 0.0
6.39PheAsp: 6.39 ± 1.355
0.0PheGlu: 0.0 ± 0.0
3.195PhePhe: 3.195 ± 1.843
1.597PheGly: 1.597 ± 1.409
1.597PheHis: 1.597 ± 0.922
0.0PheIle: 0.0 ± 0.0
3.195PheLys: 3.195 ± 2.819
4.792PheLeu: 4.792 ± 2.765
0.0PheMet: 0.0 ± 0.0
4.792PheAsn: 4.792 ± 0.434
1.597PhePro: 1.597 ± 1.409
1.597PheGln: 1.597 ± 1.409
1.597PheArg: 1.597 ± 1.409
0.0PheSer: 0.0 ± 0.0
4.792PheThr: 4.792 ± 0.434
4.792PheVal: 4.792 ± 1.897
0.0PheTrp: 0.0 ± 0.0
1.597PheTyr: 1.597 ± 1.409
0.0PheXaa: 0.0 ± 0.0
Gly
4.792GlyAla: 4.792 ± 0.434
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
3.195GlyGlu: 3.195 ± 0.488
0.0GlyPhe: 0.0 ± 0.0
4.792GlyGly: 4.792 ± 0.434
1.597GlyHis: 1.597 ± 0.922
7.987GlyIle: 7.987 ± 2.277
3.195GlyLys: 3.195 ± 1.843
3.195GlyLeu: 3.195 ± 2.819
4.792GlyMet: 4.792 ± 0.434
1.597GlyAsn: 1.597 ± 0.922
1.597GlyPro: 1.597 ± 0.922
1.597GlyGln: 1.597 ± 1.409
6.39GlyArg: 6.39 ± 1.355
14.377GlySer: 14.377 ± 8.022
6.39GlyThr: 6.39 ± 3.306
4.792GlyVal: 4.792 ± 1.897
0.0GlyTrp: 0.0 ± 0.0
1.597GlyTyr: 1.597 ± 1.409
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
3.195HisAsp: 3.195 ± 2.819
0.0HisGlu: 0.0 ± 0.0
1.597HisPhe: 1.597 ± 1.409
1.597HisGly: 1.597 ± 0.922
1.597HisHis: 1.597 ± 0.922
0.0HisIle: 0.0 ± 0.0
1.597HisLys: 1.597 ± 0.922
1.597HisLeu: 1.597 ± 0.922
1.597HisMet: 1.597 ± 1.409
0.0HisAsn: 0.0 ± 0.0
4.792HisPro: 4.792 ± 0.434
3.195HisGln: 3.195 ± 1.843
1.597HisArg: 1.597 ± 1.409
1.597HisSer: 1.597 ± 0.922
1.597HisThr: 1.597 ± 0.922
4.792HisVal: 4.792 ± 2.765
1.597HisTrp: 1.597 ± 0.922
3.195HisTyr: 3.195 ± 1.843
0.0HisXaa: 0.0 ± 0.0
Ile
1.597IleAla: 1.597 ± 1.409
0.0IleCys: 0.0 ± 0.0
3.195IleAsp: 3.195 ± 1.843
3.195IleGlu: 3.195 ± 0.488
1.597IlePhe: 1.597 ± 1.409
3.195IleGly: 3.195 ± 2.819
3.195IleHis: 3.195 ± 0.488
4.792IleIle: 4.792 ± 0.434
1.597IleLys: 1.597 ± 1.409
4.792IleLeu: 4.792 ± 2.765
1.597IleMet: 1.597 ± 0.922
0.0IleAsn: 0.0 ± 0.0
4.792IlePro: 4.792 ± 4.228
0.0IleGln: 0.0 ± 0.0
7.987IleArg: 7.987 ± 2.277
4.792IleSer: 4.792 ± 1.897
0.0IleThr: 0.0 ± 0.0
1.597IleVal: 1.597 ± 0.922
3.195IleTrp: 3.195 ± 1.843
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.195LysAla: 3.195 ± 0.488
0.0LysCys: 0.0 ± 0.0
3.195LysAsp: 3.195 ± 0.488
1.597LysGlu: 1.597 ± 0.922
3.195LysPhe: 3.195 ± 2.819
6.39LysGly: 6.39 ± 0.976
0.0LysHis: 0.0 ± 0.0
1.597LysIle: 1.597 ± 1.409
4.792LysLys: 4.792 ± 1.897
3.195LysLeu: 3.195 ± 0.488
1.597LysMet: 1.597 ± 1.409
4.792LysAsn: 4.792 ± 2.765
4.792LysPro: 4.792 ± 0.434
0.0LysGln: 0.0 ± 0.0
3.195LysArg: 3.195 ± 2.819
6.39LysSer: 6.39 ± 0.976
6.39LysThr: 6.39 ± 1.355
0.0LysVal: 0.0 ± 0.0
3.195LysTrp: 3.195 ± 1.843
1.597LysTyr: 1.597 ± 0.922
0.0LysXaa: 0.0 ± 0.0
Leu
3.195LeuAla: 3.195 ± 1.843
4.792LeuCys: 4.792 ± 2.765
6.39LeuAsp: 6.39 ± 3.686
4.792LeuGlu: 4.792 ± 0.434
1.597LeuPhe: 1.597 ± 1.409
9.585LeuGly: 9.585 ± 1.463
3.195LeuHis: 3.195 ± 1.843
6.39LeuIle: 6.39 ± 3.686
0.0LeuLys: 0.0 ± 0.0
3.195LeuLeu: 3.195 ± 1.843
0.0LeuMet: 0.0 ± 0.0
1.597LeuAsn: 1.597 ± 0.922
4.792LeuPro: 4.792 ± 2.765
1.597LeuGln: 1.597 ± 0.922
4.792LeuArg: 4.792 ± 1.897
7.987LeuSer: 7.987 ± 4.716
7.987LeuThr: 7.987 ± 0.054
1.597LeuVal: 1.597 ± 0.922
0.0LeuTrp: 0.0 ± 0.0
1.597LeuTyr: 1.597 ± 0.922
0.0LeuXaa: 0.0 ± 0.0
Met
3.195MetAla: 3.195 ± 0.488
1.597MetCys: 1.597 ± 0.922
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.597MetLeu: 1.597 ± 0.922
0.0MetMet: 0.0 ± 0.0
3.195MetAsn: 3.195 ± 0.488
1.597MetPro: 1.597 ± 0.922
3.195MetGln: 3.195 ± 2.819
1.597MetArg: 1.597 ± 0.922
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
1.597MetVal: 1.597 ± 1.409
1.597MetTrp: 1.597 ± 0.922
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.195AsnAla: 3.195 ± 0.488
1.597AsnCys: 1.597 ± 0.922
1.597AsnAsp: 1.597 ± 0.922
4.792AsnGlu: 4.792 ± 0.434
0.0AsnPhe: 0.0 ± 0.0
6.39AsnGly: 6.39 ± 1.355
1.597AsnHis: 1.597 ± 0.922
1.597AsnIle: 1.597 ± 1.409
1.597AsnLys: 1.597 ± 0.922
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.195AsnPro: 3.195 ± 0.488
0.0AsnGln: 0.0 ± 0.0
1.597AsnArg: 1.597 ± 0.922
0.0AsnSer: 0.0 ± 0.0
1.597AsnThr: 1.597 ± 1.409
1.597AsnVal: 1.597 ± 0.922
3.195AsnTrp: 3.195 ± 1.843
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
7.987ProAsp: 7.987 ± 0.054
4.792ProGlu: 4.792 ± 2.765
3.195ProPhe: 3.195 ± 0.488
1.597ProGly: 1.597 ± 0.922
1.597ProHis: 1.597 ± 1.409
3.195ProIle: 3.195 ± 0.488
6.39ProLys: 6.39 ± 3.686
4.792ProLeu: 4.792 ± 1.897
0.0ProMet: 0.0 ± 0.0
3.195ProAsn: 3.195 ± 1.843
3.195ProPro: 3.195 ± 1.843
0.0ProGln: 0.0 ± 0.0
6.39ProArg: 6.39 ± 3.686
1.597ProSer: 1.597 ± 1.409
3.195ProThr: 3.195 ± 0.488
3.195ProVal: 3.195 ± 0.488
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.195GlnAla: 3.195 ± 1.843
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.792GlnGlu: 4.792 ± 2.765
0.0GlnPhe: 0.0 ± 0.0
3.195GlnGly: 3.195 ± 0.488
1.597GlnHis: 1.597 ± 0.922
3.195GlnIle: 3.195 ± 2.819
0.0GlnLys: 0.0 ± 0.0
1.597GlnLeu: 1.597 ± 0.922
1.597GlnMet: 1.597 ± 1.409
0.0GlnAsn: 0.0 ± 0.0
4.792GlnPro: 4.792 ± 2.765
0.0GlnGln: 0.0 ± 0.0
1.597GlnArg: 1.597 ± 1.409
1.597GlnSer: 1.597 ± 1.409
1.597GlnThr: 1.597 ± 1.409
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
1.597GlnTyr: 1.597 ± 1.409
0.0GlnXaa: 0.0 ± 0.0
Arg
9.585ArgAla: 9.585 ± 0.868
0.0ArgCys: 0.0 ± 0.0
1.597ArgAsp: 1.597 ± 0.922
3.195ArgGlu: 3.195 ± 1.843
6.39ArgPhe: 6.39 ± 0.976
4.792ArgGly: 4.792 ± 1.897
4.792ArgHis: 4.792 ± 0.434
0.0ArgIle: 0.0 ± 0.0
11.182ArgLys: 11.182 ± 2.873
6.39ArgLeu: 6.39 ± 1.355
0.0ArgMet: 0.0 ± 0.0
3.195ArgAsn: 3.195 ± 1.843
3.195ArgPro: 3.195 ± 1.843
0.0ArgGln: 0.0 ± 0.0
4.792ArgArg: 4.792 ± 1.897
1.597ArgSer: 1.597 ± 0.922
1.597ArgThr: 1.597 ± 0.922
0.0ArgVal: 0.0 ± 0.0
4.792ArgTrp: 4.792 ± 1.897
3.195ArgTyr: 3.195 ± 1.843
0.0ArgXaa: 0.0 ± 0.0
Ser
6.39SerAla: 6.39 ± 5.637
0.0SerCys: 0.0 ± 0.0
4.792SerAsp: 4.792 ± 1.897
4.792SerGlu: 4.792 ± 4.228
7.987SerPhe: 7.987 ± 2.277
3.195SerGly: 3.195 ± 0.488
1.597SerHis: 1.597 ± 1.409
3.195SerIle: 3.195 ± 0.488
4.792SerLys: 4.792 ± 4.228
9.585SerLeu: 9.585 ± 3.198
0.0SerMet: 0.0 ± 0.0
3.195SerAsn: 3.195 ± 0.488
1.597SerPro: 1.597 ± 1.409
3.195SerGln: 3.195 ± 0.488
3.195SerArg: 3.195 ± 2.819
7.987SerSer: 7.987 ± 2.385
3.195SerThr: 3.195 ± 2.819
1.597SerVal: 1.597 ± 1.409
1.597SerTrp: 1.597 ± 0.922
3.195SerTyr: 3.195 ± 1.843
0.0SerXaa: 0.0 ± 0.0
Thr
4.792ThrAla: 4.792 ± 1.897
0.0ThrCys: 0.0 ± 0.0
3.195ThrAsp: 3.195 ± 2.819
0.0ThrGlu: 0.0 ± 0.0
1.597ThrPhe: 1.597 ± 1.409
1.597ThrGly: 1.597 ± 0.922
1.597ThrHis: 1.597 ± 0.922
0.0ThrIle: 0.0 ± 0.0
4.792ThrLys: 4.792 ± 0.434
4.792ThrLeu: 4.792 ± 0.434
0.0ThrMet: 0.0 ± 0.0
1.597ThrAsn: 1.597 ± 0.922
3.195ThrPro: 3.195 ± 0.488
1.597ThrGln: 1.597 ± 1.409
7.987ThrArg: 7.987 ± 2.277
1.597ThrSer: 1.597 ± 0.922
7.987ThrThr: 7.987 ± 2.277
7.987ThrVal: 7.987 ± 0.054
1.597ThrTrp: 1.597 ± 1.409
4.792ThrTyr: 4.792 ± 1.897
0.0ThrXaa: 0.0 ± 0.0
Val
7.987ValAla: 7.987 ± 0.054
0.0ValCys: 0.0 ± 0.0
3.195ValAsp: 3.195 ± 1.843
3.195ValGlu: 3.195 ± 0.488
0.0ValPhe: 0.0 ± 0.0
6.39ValGly: 6.39 ± 3.306
1.597ValHis: 1.597 ± 0.922
1.597ValIle: 1.597 ± 1.409
1.597ValLys: 1.597 ± 0.922
7.987ValLeu: 7.987 ± 0.054
1.597ValMet: 1.597 ± 0.922
0.0ValAsn: 0.0 ± 0.0
3.195ValPro: 3.195 ± 1.843
1.597ValGln: 1.597 ± 0.922
1.597ValArg: 1.597 ± 1.409
3.195ValSer: 3.195 ± 2.819
1.597ValThr: 1.597 ± 0.922
1.597ValVal: 1.597 ± 0.922
1.597ValTrp: 1.597 ± 1.409
4.792ValTyr: 4.792 ± 1.897
0.0ValXaa: 0.0 ± 0.0
Trp
1.597TrpAla: 1.597 ± 0.922
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.597TrpPhe: 1.597 ± 1.409
4.792TrpGly: 4.792 ± 2.765
0.0TrpHis: 0.0 ± 0.0
1.597TrpIle: 1.597 ± 0.922
0.0TrpLys: 0.0 ± 0.0
3.195TrpLeu: 3.195 ± 1.843
1.597TrpMet: 1.597 ± 0.922
1.597TrpAsn: 1.597 ± 1.409
0.0TrpPro: 0.0 ± 0.0
1.597TrpGln: 1.597 ± 1.409
3.195TrpArg: 3.195 ± 1.843
1.597TrpSer: 1.597 ± 1.409
1.597TrpThr: 1.597 ± 0.922
1.597TrpVal: 1.597 ± 1.409
0.0TrpTrp: 0.0 ± 0.0
1.597TrpTyr: 1.597 ± 0.922
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.195TyrAla: 3.195 ± 1.843
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
3.195TyrPhe: 3.195 ± 2.819
1.597TyrGly: 1.597 ± 1.409
1.597TyrHis: 1.597 ± 0.922
4.792TyrIle: 4.792 ± 0.434
0.0TyrLys: 0.0 ± 0.0
4.792TyrLeu: 4.792 ± 1.897
1.597TyrMet: 1.597 ± 0.922
0.0TyrAsn: 0.0 ± 0.0
1.597TyrPro: 1.597 ± 0.922
3.195TyrGln: 3.195 ± 1.843
3.195TyrArg: 3.195 ± 0.488
6.39TyrSer: 6.39 ± 0.976
0.0TyrThr: 0.0 ± 0.0
1.597TyrVal: 1.597 ± 0.922
1.597TyrTrp: 1.597 ± 1.409
3.195TyrTyr: 3.195 ± 0.488
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (627 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski