Amino acid dipepetide frequency for Ziziphus jujuba witches -broom phytoplasma

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.283AlaAla: 1.283 ± 0.115
0.356AlaCys: 0.356 ± 0.045
1.383AlaAsp: 1.383 ± 0.096
1.966AlaGlu: 1.966 ± 0.182
1.878AlaPhe: 1.878 ± 0.118
1.661AlaGly: 1.661 ± 0.114
0.544AlaHis: 0.544 ± 0.054
3.438AlaIle: 3.438 ± 0.169
4.138AlaLys: 4.138 ± 0.36
3.605AlaLeu: 3.605 ± 0.141
0.6AlaMet: 0.6 ± 0.06
2.239AlaAsn: 2.239 ± 0.181
0.744AlaPro: 0.744 ± 0.074
1.644AlaGln: 1.644 ± 0.18
1.217AlaArg: 1.217 ± 0.095
2.25AlaSer: 2.25 ± 0.134
1.939AlaThr: 1.939 ± 0.184
1.739AlaVal: 1.739 ± 0.124
0.183AlaTrp: 0.183 ± 0.028
1.289AlaTyr: 1.289 ± 0.102
0.0AlaXaa: 0.0 ± 0.0
Cys
0.25CysAla: 0.25 ± 0.049
0.106CysCys: 0.106 ± 0.027
0.511CysAsp: 0.511 ± 0.049
0.522CysGlu: 0.522 ± 0.056
0.867CysPhe: 0.867 ± 0.075
0.455CysGly: 0.455 ± 0.062
0.194CysHis: 0.194 ± 0.032
0.883CysIle: 0.883 ± 0.072
0.572CysLys: 0.572 ± 0.062
1.122CysLeu: 1.122 ± 0.088
0.089CysMet: 0.089 ± 0.024
0.5CysAsn: 0.5 ± 0.059
0.367CysPro: 0.367 ± 0.048
0.489CysGln: 0.489 ± 0.053
0.222CysArg: 0.222 ± 0.034
0.678CysSer: 0.678 ± 0.069
0.289CysThr: 0.289 ± 0.043
0.439CysVal: 0.439 ± 0.048
0.056CysTrp: 0.056 ± 0.024
0.505CysTyr: 0.505 ± 0.059
0.0CysXaa: 0.0 ± 0.0
Asp
1.483AspAla: 1.483 ± 0.097
0.417AspCys: 0.417 ± 0.048
2.177AspAsp: 2.177 ± 0.135
3.327AspGlu: 3.327 ± 0.157
3.627AspPhe: 3.627 ± 0.172
1.739AspGly: 1.739 ± 0.127
0.617AspHis: 0.617 ± 0.062
5.399AspIle: 5.399 ± 0.214
6.216AspLys: 6.216 ± 0.233
5.994AspLeu: 5.994 ± 0.191
0.672AspMet: 0.672 ± 0.069
3.494AspAsn: 3.494 ± 0.173
1.222AspPro: 1.222 ± 0.105
1.539AspGln: 1.539 ± 0.099
1.211AspArg: 1.211 ± 0.082
3.127AspSer: 3.127 ± 0.211
2.122AspThr: 2.122 ± 0.165
2.527AspVal: 2.527 ± 0.13
0.294AspTrp: 0.294 ± 0.043
2.261AspTyr: 2.261 ± 0.111
0.0AspXaa: 0.0 ± 0.0
Glu
3.477GluAla: 3.477 ± 0.287
0.572GluCys: 0.572 ± 0.056
3.066GluAsp: 3.066 ± 0.153
6.36GluGlu: 6.36 ± 0.301
2.705GluPhe: 2.705 ± 0.127
2.433GluGly: 2.433 ± 0.143
1.044GluHis: 1.044 ± 0.084
8.91GluIle: 8.91 ± 0.269
9.449GluLys: 9.449 ± 0.327
6.405GluLeu: 6.405 ± 0.408
1.578GluMet: 1.578 ± 0.087
5.838GluAsn: 5.838 ± 0.234
1.394GluPro: 1.394 ± 0.099
3.638GluGln: 3.638 ± 0.185
1.694GluArg: 1.694 ± 0.11
2.905GluSer: 2.905 ± 0.143
3.677GluThr: 3.677 ± 0.186
3.35GluVal: 3.35 ± 0.335
0.328GluTrp: 0.328 ± 0.043
2.477GluTyr: 2.477 ± 0.149
0.0GluXaa: 0.0 ± 0.0
Phe
1.544PheAla: 1.544 ± 0.108
0.811PheCys: 0.811 ± 0.074
3.033PheAsp: 3.033 ± 0.127
3.244PheGlu: 3.244 ± 0.161
4.744PhePhe: 4.744 ± 0.195
2.0PheGly: 2.0 ± 0.122
0.917PheHis: 0.917 ± 0.087
6.377PheIle: 6.377 ± 0.234
5.538PheLys: 5.538 ± 0.208
8.271PheLeu: 8.271 ± 0.285
0.95PheMet: 0.95 ± 0.092
3.999PheAsn: 3.999 ± 0.149
1.283PhePro: 1.283 ± 0.087
2.394PheGln: 2.394 ± 0.132
1.566PheArg: 1.566 ± 0.163
3.916PheSer: 3.916 ± 0.16
2.311PheThr: 2.311 ± 0.178
2.983PheVal: 2.983 ± 0.143
0.406PheTrp: 0.406 ± 0.053
2.95PheTyr: 2.95 ± 0.16
0.0PheXaa: 0.0 ± 0.0
Gly
1.994GlyAla: 1.994 ± 0.142
0.394GlyCys: 0.394 ± 0.045
1.616GlyAsp: 1.616 ± 0.113
2.75GlyGlu: 2.75 ± 0.335
2.5GlyPhe: 2.5 ± 0.133
2.172GlyGly: 2.172 ± 0.161
0.889GlyHis: 0.889 ± 0.08
4.099GlyIle: 4.099 ± 0.171
3.855GlyLys: 3.855 ± 0.184
3.455GlyLeu: 3.455 ± 0.172
0.794GlyMet: 0.794 ± 0.064
2.305GlyAsn: 2.305 ± 0.124
1.1GlyPro: 1.1 ± 0.078
1.45GlyGln: 1.45 ± 0.119
1.35GlyArg: 1.35 ± 0.111
2.483GlySer: 2.483 ± 0.128
2.289GlyThr: 2.289 ± 0.138
2.5GlyVal: 2.5 ± 0.136
0.267GlyTrp: 0.267 ± 0.043
1.711GlyTyr: 1.711 ± 0.107
0.0GlyXaa: 0.0 ± 0.0
His
0.622HisAla: 0.622 ± 0.062
0.161HisCys: 0.161 ± 0.025
0.739HisAsp: 0.739 ± 0.072
0.967HisGlu: 0.967 ± 0.069
1.028HisPhe: 1.028 ± 0.081
0.717HisGly: 0.717 ± 0.065
0.389HisHis: 0.389 ± 0.048
1.35HisIle: 1.35 ± 0.103
1.644HisLys: 1.644 ± 0.1
1.855HisLeu: 1.855 ± 0.122
0.217HisMet: 0.217 ± 0.034
1.211HisAsn: 1.211 ± 0.095
0.622HisPro: 0.622 ± 0.073
0.767HisGln: 0.767 ± 0.086
0.572HisArg: 0.572 ± 0.057
0.989HisSer: 0.989 ± 0.079
0.478HisThr: 0.478 ± 0.057
0.633HisVal: 0.633 ± 0.068
0.056HisTrp: 0.056 ± 0.016
0.733HisTyr: 0.733 ± 0.061
0.0HisXaa: 0.0 ± 0.0
Ile
3.655IleAla: 3.655 ± 0.154
1.111IleCys: 1.111 ± 0.094
5.788IleAsp: 5.788 ± 0.222
7.31IleGlu: 7.31 ± 0.29
6.699IlePhe: 6.699 ± 0.253
4.088IleGly: 4.088 ± 0.195
1.605IleHis: 1.605 ± 0.121
11.832IleIle: 11.832 ± 0.353
12.487IleLys: 12.487 ± 0.351
11.482IleLeu: 11.482 ± 0.327
1.655IleMet: 1.655 ± 0.095
8.41IleAsn: 8.41 ± 0.237
3.105IlePro: 3.105 ± 0.149
4.577IleGln: 4.577 ± 0.229
2.539IleArg: 2.539 ± 0.118
6.855IleSer: 6.855 ± 0.225
5.377IleThr: 5.377 ± 0.201
4.683IleVal: 4.683 ± 0.211
0.444IleTrp: 0.444 ± 0.049
3.738IleTyr: 3.738 ± 0.144
0.0IleXaa: 0.0 ± 0.0
Lys
3.744LysAla: 3.744 ± 0.187
0.794LysCys: 0.794 ± 0.083
6.36LysAsp: 6.36 ± 0.214
11.354LysGlu: 11.354 ± 0.372
4.211LysPhe: 4.211 ± 0.171
4.233LysGly: 4.233 ± 0.201
1.722LysHis: 1.722 ± 0.103
15.181LysIle: 15.181 ± 0.355
16.165LysLys: 16.165 ± 0.45
8.771LysLeu: 8.771 ± 0.247
2.733LysMet: 2.733 ± 0.131
11.826LysAsn: 11.826 ± 0.438
2.55LysPro: 2.55 ± 0.124
5.66LysGln: 5.66 ± 0.269
3.088LysArg: 3.088 ± 0.151
5.077LysSer: 5.077 ± 0.203
6.86LysThr: 6.86 ± 0.223
4.444LysVal: 4.444 ± 0.227
0.583LysTrp: 0.583 ± 0.087
4.91LysTyr: 4.91 ± 0.2
0.0LysXaa: 0.0 ± 0.0
Leu
3.533LeuAla: 3.533 ± 0.168
0.933LeuCys: 0.933 ± 0.077
4.999LeuAsp: 4.999 ± 0.195
7.471LeuGlu: 7.471 ± 0.256
6.544LeuPhe: 6.544 ± 0.276
4.983LeuGly: 4.983 ± 0.232
1.228LeuHis: 1.228 ± 0.09
9.871LeuIle: 9.871 ± 0.292
12.959LeuLys: 12.959 ± 0.302
9.465LeuLeu: 9.465 ± 0.34
1.666LeuMet: 1.666 ± 0.102
8.249LeuAsn: 8.249 ± 0.279
2.522LeuPro: 2.522 ± 0.121
3.888LeuGln: 3.888 ± 0.229
2.711LeuArg: 2.711 ± 0.162
7.155LeuSer: 7.155 ± 0.254
5.555LeuThr: 5.555 ± 0.463
4.133LeuVal: 4.133 ± 0.2
0.483LeuTrp: 0.483 ± 0.051
3.472LeuTyr: 3.472 ± 0.176
0.0LeuXaa: 0.0 ± 0.0
Met
0.65MetAla: 0.65 ± 0.052
0.133MetCys: 0.133 ± 0.026
0.7MetAsp: 0.7 ± 0.068
1.005MetGlu: 1.005 ± 0.063
0.9MetPhe: 0.9 ± 0.078
0.694MetGly: 0.694 ± 0.07
0.239MetHis: 0.239 ± 0.036
1.994MetIle: 1.994 ± 0.113
2.25MetLys: 2.25 ± 0.135
1.661MetLeu: 1.661 ± 0.12
0.256MetMet: 0.256 ± 0.038
1.555MetAsn: 1.555 ± 0.094
0.45MetPro: 0.45 ± 0.057
0.672MetGln: 0.672 ± 0.066
0.467MetArg: 0.467 ± 0.05
1.161MetSer: 1.161 ± 0.085
0.889MetThr: 0.889 ± 0.074
0.728MetVal: 0.728 ± 0.061
0.061MetTrp: 0.061 ± 0.019
0.505MetTyr: 0.505 ± 0.055
0.0MetXaa: 0.0 ± 0.0
Asn
2.272AsnAla: 2.272 ± 0.181
0.6AsnCys: 0.6 ± 0.065
3.799AsnAsp: 3.799 ± 0.214
5.238AsnGlu: 5.238 ± 0.252
4.91AsnPhe: 4.91 ± 0.197
2.072AsnGly: 2.072 ± 0.109
1.311AsnHis: 1.311 ± 0.103
9.149AsnIle: 9.149 ± 0.314
10.999AsnLys: 10.999 ± 0.277
9.199AsnLeu: 9.199 ± 0.415
1.233AsnMet: 1.233 ± 0.085
7.499AsnAsn: 7.499 ± 0.262
2.377AsnPro: 2.377 ± 0.146
3.922AsnGln: 3.922 ± 0.179
1.672AsnArg: 1.672 ± 0.099
4.005AsnSer: 4.005 ± 0.168
3.466AsnThr: 3.466 ± 0.221
2.755AsnVal: 2.755 ± 0.129
0.45AsnTrp: 0.45 ± 0.055
3.627AsnTyr: 3.627 ± 0.147
0.0AsnXaa: 0.0 ± 0.0
Pro
0.711ProAla: 0.711 ± 0.06
0.267ProCys: 0.267 ± 0.043
1.211ProAsp: 1.211 ± 0.089
2.089ProGlu: 2.089 ± 0.173
2.044ProPhe: 2.044 ± 0.119
1.205ProGly: 1.205 ± 0.098
0.572ProHis: 0.572 ± 0.061
2.172ProIle: 2.172 ± 0.124
2.739ProLys: 2.739 ± 0.141
2.511ProLeu: 2.511 ± 0.124
0.306ProMet: 0.306 ± 0.053
1.878ProAsn: 1.878 ± 0.124
0.811ProPro: 0.811 ± 0.083
1.45ProGln: 1.45 ± 0.141
0.622ProArg: 0.622 ± 0.053
1.989ProSer: 1.989 ± 0.139
1.111ProThr: 1.111 ± 0.089
1.072ProVal: 1.072 ± 0.085
0.128ProTrp: 0.128 ± 0.027
1.2ProTyr: 1.2 ± 0.096
0.0ProXaa: 0.0 ± 0.0
Gln
1.522GlnAla: 1.522 ± 0.209
0.294GlnCys: 0.294 ± 0.041
1.855GlnAsp: 1.855 ± 0.098
4.033GlnGlu: 4.033 ± 0.228
1.816GlnPhe: 1.816 ± 0.194
1.5GlnGly: 1.5 ± 0.104
0.55GlnHis: 0.55 ± 0.056
5.26GlnIle: 5.26 ± 0.225
7.01GlnLys: 7.01 ± 0.256
3.772GlnLeu: 3.772 ± 0.177
0.817GlnMet: 0.817 ± 0.073
5.044GlnAsn: 5.044 ± 0.414
0.911GlnPro: 0.911 ± 0.136
2.277GlnGln: 2.277 ± 0.211
1.239GlnArg: 1.239 ± 0.091
1.55GlnSer: 1.55 ± 0.111
2.383GlnThr: 2.383 ± 0.143
1.344GlnVal: 1.344 ± 0.097
0.228GlnTrp: 0.228 ± 0.039
1.222GlnTyr: 1.222 ± 0.089
0.0GlnXaa: 0.0 ± 0.0
Arg
0.933ArgAla: 0.933 ± 0.093
0.233ArgCys: 0.233 ± 0.039
1.378ArgAsp: 1.378 ± 0.084
1.755ArgGlu: 1.755 ± 0.1
1.444ArgPhe: 1.444 ± 0.118
1.15ArgGly: 1.15 ± 0.09
0.439ArgHis: 0.439 ± 0.047
2.7ArgIle: 2.7 ± 0.141
3.305ArgLys: 3.305 ± 0.162
2.483ArgLeu: 2.483 ± 0.119
0.55ArgMet: 0.55 ± 0.057
1.989ArgAsn: 1.989 ± 0.109
0.772ArgPro: 0.772 ± 0.083
1.283ArgGln: 1.283 ± 0.082
0.867ArgArg: 0.867 ± 0.073
1.311ArgSer: 1.311 ± 0.091
1.605ArgThr: 1.605 ± 0.224
1.111ArgVal: 1.111 ± 0.097
0.183ArgTrp: 0.183 ± 0.032
1.033ArgTyr: 1.033 ± 0.073
0.0ArgXaa: 0.0 ± 0.0
Ser
1.705SerAla: 1.705 ± 0.093
0.617SerCys: 0.617 ± 0.068
3.133SerAsp: 3.133 ± 0.177
3.688SerGlu: 3.688 ± 0.174
4.505SerPhe: 4.505 ± 0.186
2.816SerGly: 2.816 ± 0.167
0.95SerHis: 0.95 ± 0.073
5.51SerIle: 5.51 ± 0.212
5.966SerLys: 5.966 ± 0.194
6.582SerLeu: 6.582 ± 0.227
0.933SerMet: 0.933 ± 0.089
4.077SerAsn: 4.077 ± 0.175
1.544SerPro: 1.544 ± 0.115
2.505SerGln: 2.505 ± 0.126
1.694SerArg: 1.694 ± 0.118
4.066SerSer: 4.066 ± 0.156
2.8SerThr: 2.8 ± 0.336
2.322SerVal: 2.322 ± 0.119
0.361SerTrp: 0.361 ± 0.049
2.777SerTyr: 2.777 ± 0.19
0.0SerXaa: 0.0 ± 0.0
Thr
1.744ThrAla: 1.744 ± 0.248
0.333ThrCys: 0.333 ± 0.045
2.333ThrAsp: 2.333 ± 0.186
2.944ThrGlu: 2.944 ± 0.15
2.377ThrPhe: 2.377 ± 0.111
2.227ThrGly: 2.227 ± 0.138
0.872ThrHis: 0.872 ± 0.074
4.944ThrIle: 4.944 ± 0.214
6.349ThrLys: 6.349 ± 0.487
4.738ThrLeu: 4.738 ± 0.203
0.605ThrMet: 0.605 ± 0.059
4.099ThrAsn: 4.099 ± 0.197
1.816ThrPro: 1.816 ± 0.113
2.211ThrGln: 2.211 ± 0.165
1.283ThrArg: 1.283 ± 0.088
3.45ThrSer: 3.45 ± 0.351
2.722ThrThr: 2.722 ± 0.238
2.15ThrVal: 2.15 ± 0.189
0.294ThrTrp: 0.294 ± 0.046
1.916ThrTyr: 1.916 ± 0.188
0.0ThrXaa: 0.0 ± 0.0
Val
1.578ValAla: 1.578 ± 0.12
0.455ValCys: 0.455 ± 0.049
2.522ValAsp: 2.522 ± 0.188
2.627ValGlu: 2.627 ± 0.176
2.905ValPhe: 2.905 ± 0.127
2.066ValGly: 2.066 ± 0.128
0.655ValHis: 0.655 ± 0.068
4.583ValIle: 4.583 ± 0.199
3.955ValLys: 3.955 ± 0.198
4.727ValLeu: 4.727 ± 0.185
0.728ValMet: 0.728 ± 0.068
2.783ValAsn: 2.783 ± 0.111
1.244ValPro: 1.244 ± 0.092
1.733ValGln: 1.733 ± 0.279
1.222ValArg: 1.222 ± 0.102
3.055ValSer: 3.055 ± 0.121
1.828ValThr: 1.828 ± 0.119
2.6ValVal: 2.6 ± 0.16
0.228ValTrp: 0.228 ± 0.043
1.666ValTyr: 1.666 ± 0.095
0.0ValXaa: 0.0 ± 0.0
Trp
0.239TrpAla: 0.239 ± 0.04
0.056TrpCys: 0.056 ± 0.02
0.356TrpAsp: 0.356 ± 0.078
0.344TrpGlu: 0.344 ± 0.055
0.444TrpPhe: 0.444 ± 0.049
0.261TrpGly: 0.261 ± 0.036
0.122TrpHis: 0.122 ± 0.027
0.422TrpIle: 0.422 ± 0.046
0.567TrpLys: 0.567 ± 0.06
0.583TrpLeu: 0.583 ± 0.076
0.083TrpMet: 0.083 ± 0.021
0.389TrpAsn: 0.389 ± 0.051
0.139TrpPro: 0.139 ± 0.032
0.206TrpGln: 0.206 ± 0.032
0.156TrpArg: 0.156 ± 0.031
0.244TrpSer: 0.244 ± 0.039
0.183TrpThr: 0.183 ± 0.034
0.222TrpVal: 0.222 ± 0.035
0.039TrpTrp: 0.039 ± 0.015
0.256TrpTyr: 0.256 ± 0.034
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.155TyrAla: 1.155 ± 0.082
0.472TyrCys: 0.472 ± 0.055
2.505TyrAsp: 2.505 ± 0.168
2.305TyrGlu: 2.305 ± 0.109
3.088TyrPhe: 3.088 ± 0.159
1.5TyrGly: 1.5 ± 0.099
0.889TyrHis: 0.889 ± 0.074
3.366TyrIle: 3.366 ± 0.142
4.105TyrLys: 4.105 ± 0.19
5.138TyrLeu: 5.138 ± 0.227
0.5TyrMet: 0.5 ± 0.062
3.172TyrAsn: 3.172 ± 0.152
1.111TyrPro: 1.111 ± 0.076
2.322TyrGln: 2.322 ± 0.123
1.139TyrArg: 1.139 ± 0.082
2.289TyrSer: 2.289 ± 0.115
1.528TyrThr: 1.528 ± 0.109
1.428TyrVal: 1.428 ± 0.079
0.239TyrTrp: 0.239 ± 0.042
2.089TyrTyr: 2.089 ± 0.134
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 597 proteins (180025 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski