Amino acid dipepetide frequency for Fowl aviadenovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.595AlaAla: 6.595 ± 1.053
1.534AlaCys: 1.534 ± 0.36
4.217AlaAsp: 4.217 ± 0.488
4.601AlaGlu: 4.601 ± 0.632
3.374AlaPhe: 3.374 ± 0.526
4.524AlaGly: 4.524 ± 0.886
1.38AlaHis: 1.38 ± 0.339
4.217AlaIle: 4.217 ± 0.597
2.53AlaLys: 2.53 ± 0.419
7.208AlaLeu: 7.208 ± 0.827
2.147AlaMet: 2.147 ± 0.474
2.991AlaAsn: 2.991 ± 0.485
4.371AlaPro: 4.371 ± 0.48
2.914AlaGln: 2.914 ± 0.52
4.217AlaArg: 4.217 ± 0.756
5.214AlaSer: 5.214 ± 0.761
4.294AlaThr: 4.294 ± 0.49
4.294AlaVal: 4.294 ± 0.559
0.843AlaTrp: 0.843 ± 0.262
3.297AlaTyr: 3.297 ± 0.375
0.0AlaXaa: 0.0 ± 0.0
Cys
1.074CysAla: 1.074 ± 0.261
0.383CysCys: 0.383 ± 0.238
1.074CysAsp: 1.074 ± 0.343
1.304CysGlu: 1.304 ± 0.396
0.767CysPhe: 0.767 ± 0.224
1.304CysGly: 1.304 ± 0.38
0.843CysHis: 0.843 ± 0.286
0.92CysIle: 0.92 ± 0.326
0.767CysLys: 0.767 ± 0.221
1.38CysLeu: 1.38 ± 0.365
0.613CysMet: 0.613 ± 0.211
1.15CysAsn: 1.15 ± 0.334
1.534CysPro: 1.534 ± 0.337
0.383CysGln: 0.383 ± 0.272
1.15CysArg: 1.15 ± 0.315
1.917CysSer: 1.917 ± 0.47
0.843CysThr: 0.843 ± 0.226
0.613CysVal: 0.613 ± 0.206
0.383CysTrp: 0.383 ± 0.165
0.613CysTyr: 0.613 ± 0.192
0.0CysXaa: 0.0 ± 0.0
Asp
4.524AspAla: 4.524 ± 0.643
0.613AspCys: 0.613 ± 0.239
2.377AspAsp: 2.377 ± 0.371
3.527AspGlu: 3.527 ± 0.647
1.61AspPhe: 1.61 ± 0.345
2.914AspGly: 2.914 ± 0.521
0.767AspHis: 0.767 ± 0.209
2.53AspIle: 2.53 ± 0.486
1.61AspLys: 1.61 ± 0.324
5.368AspLeu: 5.368 ± 0.509
1.994AspMet: 1.994 ± 0.529
1.994AspAsn: 1.994 ± 0.522
5.061AspPro: 5.061 ± 0.645
1.917AspGln: 1.917 ± 0.296
3.987AspArg: 3.987 ± 0.595
3.451AspSer: 3.451 ± 0.601
3.604AspThr: 3.604 ± 0.583
2.147AspVal: 2.147 ± 0.306
0.613AspTrp: 0.613 ± 0.232
2.607AspTyr: 2.607 ± 0.31
0.0AspXaa: 0.0 ± 0.0
Glu
3.987GluAla: 3.987 ± 0.724
0.997GluCys: 0.997 ± 0.408
3.144GluAsp: 3.144 ± 0.396
5.751GluGlu: 5.751 ± 0.944
2.07GluPhe: 2.07 ± 0.463
3.221GluGly: 3.221 ± 0.442
1.917GluHis: 1.917 ± 0.437
3.297GluIle: 3.297 ± 0.567
1.994GluLys: 1.994 ± 0.406
6.058GluLeu: 6.058 ± 0.64
1.534GluMet: 1.534 ± 0.386
2.147GluAsn: 2.147 ± 0.387
3.221GluPro: 3.221 ± 0.686
2.53GluGln: 2.53 ± 0.462
3.527GluArg: 3.527 ± 0.636
2.377GluSer: 2.377 ± 0.309
3.297GluThr: 3.297 ± 0.615
4.294GluVal: 4.294 ± 0.533
0.69GluTrp: 0.69 ± 0.239
1.38GluTyr: 1.38 ± 0.315
0.0GluXaa: 0.0 ± 0.0
Phe
2.377PheAla: 2.377 ± 0.503
0.843PheCys: 0.843 ± 0.298
3.144PheAsp: 3.144 ± 0.665
2.3PheGlu: 2.3 ± 0.416
2.224PhePhe: 2.224 ± 0.487
1.534PheGly: 1.534 ± 0.389
1.534PheHis: 1.534 ± 0.35
1.764PheIle: 1.764 ± 0.371
2.147PheLys: 2.147 ± 0.357
3.987PheLeu: 3.987 ± 0.638
1.534PheMet: 1.534 ± 0.275
1.61PheAsn: 1.61 ± 0.308
2.3PhePro: 2.3 ± 0.492
1.38PheGln: 1.38 ± 0.367
2.837PheArg: 2.837 ± 0.399
3.604PheSer: 3.604 ± 0.422
1.994PheThr: 1.994 ± 0.264
2.454PheVal: 2.454 ± 0.379
0.69PheTrp: 0.69 ± 0.19
2.377PheTyr: 2.377 ± 0.422
0.0PheXaa: 0.0 ± 0.0
Gly
5.904GlyAla: 5.904 ± 0.709
0.843GlyCys: 0.843 ± 0.308
2.53GlyAsp: 2.53 ± 0.332
3.911GlyGlu: 3.911 ± 0.794
2.53GlyPhe: 2.53 ± 0.533
6.134GlyGly: 6.134 ± 1.474
0.843GlyHis: 0.843 ± 0.28
2.147GlyIle: 2.147 ± 0.435
1.994GlyLys: 1.994 ± 0.364
5.828GlyLeu: 5.828 ± 0.794
1.61GlyMet: 1.61 ± 0.319
2.224GlyAsn: 2.224 ± 0.407
3.527GlyPro: 3.527 ± 0.664
2.454GlyGln: 2.454 ± 0.489
4.294GlyArg: 4.294 ± 0.635
4.371GlySer: 4.371 ± 0.591
4.448GlyThr: 4.448 ± 0.574
4.217GlyVal: 4.217 ± 0.612
1.15GlyTrp: 1.15 ± 0.244
2.607GlyTyr: 2.607 ± 0.403
0.0GlyXaa: 0.0 ± 0.0
His
1.764HisAla: 1.764 ± 0.373
1.38HisCys: 1.38 ± 0.396
1.457HisAsp: 1.457 ± 0.234
0.92HisGlu: 0.92 ± 0.366
0.843HisPhe: 0.843 ± 0.226
1.84HisGly: 1.84 ± 0.455
0.69HisHis: 0.69 ± 0.212
1.074HisIle: 1.074 ± 0.254
0.69HisLys: 0.69 ± 0.2
1.84HisLeu: 1.84 ± 0.331
0.46HisMet: 0.46 ± 0.157
1.304HisAsn: 1.304 ± 0.26
1.84HisPro: 1.84 ± 0.298
0.613HisGln: 0.613 ± 0.247
1.61HisArg: 1.61 ± 0.314
1.994HisSer: 1.994 ± 0.412
1.074HisThr: 1.074 ± 0.227
1.534HisVal: 1.534 ± 0.415
0.46HisTrp: 0.46 ± 0.166
0.69HisTyr: 0.69 ± 0.219
0.0HisXaa: 0.0 ± 0.0
Ile
2.914IleAla: 2.914 ± 0.422
0.843IleCys: 0.843 ± 0.222
2.454IleAsp: 2.454 ± 0.397
2.53IleGlu: 2.53 ± 0.506
1.457IlePhe: 1.457 ± 0.275
2.454IleGly: 2.454 ± 0.47
1.38IleHis: 1.38 ± 0.374
1.15IleIle: 1.15 ± 0.245
1.687IleLys: 1.687 ± 0.381
3.297IleLeu: 3.297 ± 0.63
0.997IleMet: 0.997 ± 0.309
2.454IleAsn: 2.454 ± 0.432
3.297IlePro: 3.297 ± 0.447
1.687IleGln: 1.687 ± 0.408
2.53IleArg: 2.53 ± 0.467
3.374IleSer: 3.374 ± 0.441
2.837IleThr: 2.837 ± 0.401
2.53IleVal: 2.53 ± 0.316
0.383IleTrp: 0.383 ± 0.159
1.84IleTyr: 1.84 ± 0.237
0.0IleXaa: 0.0 ± 0.0
Lys
2.454LysAla: 2.454 ± 0.472
0.613LysCys: 0.613 ± 0.19
2.454LysAsp: 2.454 ± 0.398
1.917LysGlu: 1.917 ± 0.331
2.3LysPhe: 2.3 ± 0.465
2.147LysGly: 2.147 ± 0.381
0.92LysHis: 0.92 ± 0.329
0.843LysIle: 0.843 ± 0.247
1.764LysLys: 1.764 ± 0.342
3.297LysLeu: 3.297 ± 0.541
0.92LysMet: 0.92 ± 0.327
1.61LysAsn: 1.61 ± 0.346
2.07LysPro: 2.07 ± 0.418
1.38LysGln: 1.38 ± 0.417
3.451LysArg: 3.451 ± 0.452
1.84LysSer: 1.84 ± 0.299
2.3LysThr: 2.3 ± 0.442
2.07LysVal: 2.07 ± 0.432
0.613LysTrp: 0.613 ± 0.222
1.687LysTyr: 1.687 ± 0.288
0.0LysXaa: 0.0 ± 0.0
Leu
5.981LeuAla: 5.981 ± 0.69
1.457LeuCys: 1.457 ± 0.256
5.138LeuAsp: 5.138 ± 0.594
4.601LeuGlu: 4.601 ± 0.507
4.141LeuPhe: 4.141 ± 0.595
5.291LeuGly: 5.291 ± 0.537
2.3LeuHis: 2.3 ± 0.574
3.374LeuIle: 3.374 ± 0.519
4.678LeuLys: 4.678 ± 0.556
6.748LeuLeu: 6.748 ± 0.669
1.994LeuMet: 1.994 ± 0.347
3.834LeuAsn: 3.834 ± 0.608
4.908LeuPro: 4.908 ± 0.549
5.061LeuGln: 5.061 ± 0.567
6.901LeuArg: 6.901 ± 0.74
5.751LeuSer: 5.751 ± 0.775
6.441LeuThr: 6.441 ± 0.581
5.138LeuVal: 5.138 ± 0.696
1.15LeuTrp: 1.15 ± 0.263
3.987LeuTyr: 3.987 ± 0.667
0.0LeuXaa: 0.0 ± 0.0
Met
2.991MetAla: 2.991 ± 0.595
0.46MetCys: 0.46 ± 0.193
1.227MetAsp: 1.227 ± 0.363
1.84MetGlu: 1.84 ± 0.549
0.997MetPhe: 0.997 ± 0.264
1.38MetGly: 1.38 ± 0.319
0.843MetHis: 0.843 ± 0.277
0.767MetIle: 0.767 ± 0.234
0.767MetLys: 0.767 ± 0.286
2.607MetLeu: 2.607 ± 0.4
0.69MetMet: 0.69 ± 0.179
1.074MetAsn: 1.074 ± 0.305
1.917MetPro: 1.917 ± 0.364
0.843MetGln: 0.843 ± 0.245
1.687MetArg: 1.687 ± 0.484
1.687MetSer: 1.687 ± 0.308
1.304MetThr: 1.304 ± 0.29
2.147MetVal: 2.147 ± 0.383
0.307MetTrp: 0.307 ± 0.154
0.92MetTyr: 0.92 ± 0.255
0.0MetXaa: 0.0 ± 0.0
Asn
3.987AsnAla: 3.987 ± 0.563
0.767AsnCys: 0.767 ± 0.243
1.84AsnAsp: 1.84 ± 0.41
1.227AsnGlu: 1.227 ± 0.338
2.3AsnPhe: 2.3 ± 0.682
2.377AsnGly: 2.377 ± 0.521
0.997AsnHis: 0.997 ± 0.246
1.994AsnIle: 1.994 ± 0.51
1.534AsnLys: 1.534 ± 0.427
2.761AsnLeu: 2.761 ± 0.497
1.227AsnMet: 1.227 ± 0.399
2.07AsnAsn: 2.07 ± 0.358
3.834AsnPro: 3.834 ± 0.536
1.994AsnGln: 1.994 ± 0.415
2.761AsnArg: 2.761 ± 0.456
2.684AsnSer: 2.684 ± 0.491
2.914AsnThr: 2.914 ± 0.586
2.761AsnVal: 2.761 ± 0.709
0.69AsnTrp: 0.69 ± 0.349
2.3AsnTyr: 2.3 ± 0.383
0.0AsnXaa: 0.0 ± 0.0
Pro
4.371ProAla: 4.371 ± 0.526
0.767ProCys: 0.767 ± 0.231
3.604ProAsp: 3.604 ± 0.579
4.524ProGlu: 4.524 ± 0.726
3.681ProPhe: 3.681 ± 0.468
3.144ProGly: 3.144 ± 0.486
1.994ProHis: 1.994 ± 0.367
3.067ProIle: 3.067 ± 0.595
2.53ProLys: 2.53 ± 0.531
5.444ProLeu: 5.444 ± 0.764
1.994ProMet: 1.994 ± 0.477
2.3ProAsn: 2.3 ± 0.432
7.208ProPro: 7.208 ± 1.021
2.53ProGln: 2.53 ± 0.454
3.604ProArg: 3.604 ± 0.458
5.368ProSer: 5.368 ± 0.994
5.061ProThr: 5.061 ± 0.967
3.834ProVal: 3.834 ± 0.678
0.383ProTrp: 0.383 ± 0.16
3.374ProTyr: 3.374 ± 0.549
0.0ProXaa: 0.0 ± 0.0
Gln
2.761GlnAla: 2.761 ± 0.561
0.69GlnCys: 0.69 ± 0.239
0.997GlnAsp: 0.997 ± 0.199
2.684GlnGlu: 2.684 ± 0.421
1.15GlnPhe: 1.15 ± 0.334
2.914GlnGly: 2.914 ± 0.595
1.61GlnHis: 1.61 ± 0.475
1.457GlnIle: 1.457 ± 0.278
1.074GlnLys: 1.074 ± 0.267
4.601GlnLeu: 4.601 ± 0.488
1.074GlnMet: 1.074 ± 0.321
2.224GlnAsn: 2.224 ± 0.474
2.07GlnPro: 2.07 ± 0.507
2.991GlnGln: 2.991 ± 0.684
3.144GlnArg: 3.144 ± 0.632
2.07GlnSer: 2.07 ± 0.336
2.224GlnThr: 2.224 ± 0.337
1.84GlnVal: 1.84 ± 0.378
0.69GlnTrp: 0.69 ± 0.25
2.07GlnTyr: 2.07 ± 0.535
0.0GlnXaa: 0.0 ± 0.0
Arg
4.831ArgAla: 4.831 ± 0.703
1.227ArgCys: 1.227 ± 0.396
3.911ArgAsp: 3.911 ± 0.668
3.144ArgGlu: 3.144 ± 0.561
3.297ArgPhe: 3.297 ± 0.382
4.217ArgGly: 4.217 ± 0.764
1.38ArgHis: 1.38 ± 0.366
2.607ArgIle: 2.607 ± 0.58
2.914ArgLys: 2.914 ± 0.596
4.908ArgLeu: 4.908 ± 0.589
2.07ArgMet: 2.07 ± 0.374
3.297ArgAsn: 3.297 ± 0.73
3.834ArgPro: 3.834 ± 0.536
3.067ArgGln: 3.067 ± 0.575
7.745ArgArg: 7.745 ± 1.323
5.598ArgSer: 5.598 ± 0.724
3.987ArgThr: 3.987 ± 0.54
3.911ArgVal: 3.911 ± 0.668
1.534ArgTrp: 1.534 ± 0.283
2.53ArgTyr: 2.53 ± 0.453
0.0ArgXaa: 0.0 ± 0.0
Ser
5.904SerAla: 5.904 ± 0.719
1.84SerCys: 1.84 ± 0.402
4.064SerAsp: 4.064 ± 0.538
4.141SerGlu: 4.141 ± 0.608
2.3SerPhe: 2.3 ± 0.332
5.981SerGly: 5.981 ± 1.092
1.764SerHis: 1.764 ± 0.393
3.451SerIle: 3.451 ± 0.464
2.07SerLys: 2.07 ± 0.535
5.214SerLeu: 5.214 ± 0.77
1.534SerMet: 1.534 ± 0.376
1.994SerAsn: 1.994 ± 0.32
5.138SerPro: 5.138 ± 0.87
2.454SerGln: 2.454 ± 0.525
4.678SerArg: 4.678 ± 0.618
5.138SerSer: 5.138 ± 0.722
4.371SerThr: 4.371 ± 0.61
4.294SerVal: 4.294 ± 0.531
0.767SerTrp: 0.767 ± 0.285
1.61SerTyr: 1.61 ± 0.605
0.0SerXaa: 0.0 ± 0.0
Thr
5.751ThrAla: 5.751 ± 0.772
0.92ThrCys: 0.92 ± 0.308
3.297ThrAsp: 3.297 ± 0.368
3.527ThrGlu: 3.527 ± 0.388
2.3ThrPhe: 2.3 ± 0.29
5.214ThrGly: 5.214 ± 0.678
0.613ThrHis: 0.613 ± 0.195
3.067ThrIle: 3.067 ± 0.525
1.687ThrLys: 1.687 ± 0.405
5.138ThrLeu: 5.138 ± 0.719
1.074ThrMet: 1.074 ± 0.32
2.684ThrAsn: 2.684 ± 0.654
5.291ThrPro: 5.291 ± 0.975
1.61ThrGln: 1.61 ± 0.424
3.527ThrArg: 3.527 ± 0.534
4.448ThrSer: 4.448 ± 0.414
7.285ThrThr: 7.285 ± 3.55
4.371ThrVal: 4.371 ± 0.647
0.69ThrTrp: 0.69 ± 0.221
2.837ThrTyr: 2.837 ± 0.591
0.0ThrXaa: 0.0 ± 0.0
Val
3.527ValAla: 3.527 ± 0.445
1.38ValCys: 1.38 ± 0.508
3.067ValAsp: 3.067 ± 0.686
2.224ValGlu: 2.224 ± 0.587
2.837ValPhe: 2.837 ± 0.452
3.604ValGly: 3.604 ± 0.467
1.227ValHis: 1.227 ± 0.291
2.454ValIle: 2.454 ± 0.504
1.917ValLys: 1.917 ± 0.385
7.361ValLeu: 7.361 ± 0.617
0.92ValMet: 0.92 ± 0.193
3.067ValAsn: 3.067 ± 0.592
4.754ValPro: 4.754 ± 0.719
2.454ValGln: 2.454 ± 0.501
4.294ValArg: 4.294 ± 0.612
4.371ValSer: 4.371 ± 0.773
3.757ValThr: 3.757 ± 0.612
4.141ValVal: 4.141 ± 0.632
0.69ValTrp: 0.69 ± 0.273
2.53ValTyr: 2.53 ± 0.342
0.0ValXaa: 0.0 ± 0.0
Trp
0.843TrpAla: 0.843 ± 0.217
0.537TrpCys: 0.537 ± 0.258
0.613TrpAsp: 0.613 ± 0.193
0.767TrpGlu: 0.767 ± 0.229
0.69TrpPhe: 0.69 ± 0.223
1.15TrpGly: 1.15 ± 0.324
0.077TrpHis: 0.077 ± 0.071
0.613TrpIle: 0.613 ± 0.158
0.69TrpLys: 0.69 ± 0.251
1.38TrpLeu: 1.38 ± 0.357
0.307TrpMet: 0.307 ± 0.137
0.767TrpAsn: 0.767 ± 0.178
0.613TrpPro: 0.613 ± 0.371
0.69TrpGln: 0.69 ± 0.201
0.843TrpArg: 0.843 ± 0.338
0.843TrpSer: 0.843 ± 0.316
0.997TrpThr: 0.997 ± 0.261
0.92TrpVal: 0.92 ± 0.251
0.0TrpTrp: 0.0 ± 0.0
0.383TrpTyr: 0.383 ± 0.139
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.224TyrAla: 2.224 ± 0.4
0.92TyrCys: 0.92 ± 0.207
2.607TyrAsp: 2.607 ± 0.509
1.994TyrGlu: 1.994 ± 0.538
1.764TyrPhe: 1.764 ± 0.54
2.3TyrGly: 2.3 ± 0.368
0.997TyrHis: 0.997 ± 0.236
1.304TyrIle: 1.304 ± 0.348
1.61TyrLys: 1.61 ± 0.402
4.448TyrLeu: 4.448 ± 0.658
1.687TyrMet: 1.687 ± 0.397
2.224TyrAsn: 2.224 ± 0.496
1.994TyrPro: 1.994 ± 0.313
1.38TyrGln: 1.38 ± 0.413
3.221TyrArg: 3.221 ± 0.609
2.607TyrSer: 2.607 ± 0.433
2.3TyrThr: 2.3 ± 0.415
3.067TyrVal: 3.067 ± 0.503
0.997TyrTrp: 0.997 ± 0.277
1.074TyrTyr: 1.074 ± 0.333
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 42 proteins (13042 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski