Amino acid dipepetide frequency for Cyclovirus Chimp11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
0.0AlaGlu: 0.0 ± 0.0
6.012AlaPhe: 6.012 ± 1.829
0.0AlaGly: 0.0 ± 0.0
0.0AlaHis: 0.0 ± 0.0
4.008AlaIle: 4.008 ± 0.323
4.008AlaLys: 4.008 ± 2.364
4.008AlaLeu: 4.008 ± 0.323
0.0AlaMet: 0.0 ± 0.0
8.016AlaAsn: 8.016 ± 3.334
2.004AlaPro: 2.004 ± 1.505
2.004AlaGln: 2.004 ± 1.505
0.0AlaArg: 0.0 ± 0.0
2.004AlaSer: 2.004 ± 1.505
6.012AlaThr: 6.012 ± 0.859
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
6.012AlaTyr: 6.012 ± 0.859
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.004CysAsp: 2.004 ± 1.182
2.004CysGlu: 2.004 ± 1.182
4.008CysPhe: 4.008 ± 0.323
2.004CysGly: 2.004 ± 1.505
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.004CysLeu: 2.004 ± 1.505
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.004CysPro: 2.004 ± 1.182
0.0CysGln: 0.0 ± 0.0
2.004CysArg: 2.004 ± 1.182
2.004CysSer: 2.004 ± 1.505
2.004CysThr: 2.004 ± 1.505
2.004CysVal: 2.004 ± 1.182
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.004AspAla: 2.004 ± 1.182
0.0AspCys: 0.0 ± 0.0
2.004AspAsp: 2.004 ± 1.182
4.008AspGlu: 4.008 ± 2.364
6.012AspPhe: 6.012 ± 1.829
2.004AspGly: 2.004 ± 1.182
0.0AspHis: 0.0 ± 0.0
4.008AspIle: 4.008 ± 0.323
2.004AspLys: 2.004 ± 1.505
4.008AspLeu: 4.008 ± 2.364
2.004AspMet: 2.004 ± 1.505
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
2.004AspArg: 2.004 ± 1.182
0.0AspSer: 0.0 ± 0.0
4.008AspThr: 4.008 ± 2.364
2.004AspVal: 2.004 ± 1.505
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.004GluAla: 2.004 ± 1.182
2.004GluCys: 2.004 ± 1.505
0.0GluAsp: 0.0 ± 0.0
4.008GluGlu: 4.008 ± 2.364
4.008GluPhe: 4.008 ± 2.364
4.008GluGly: 4.008 ± 3.011
2.004GluHis: 2.004 ± 1.182
4.008GluIle: 4.008 ± 2.364
4.008GluLys: 4.008 ± 2.364
4.008GluLeu: 4.008 ± 2.364
0.0GluMet: 0.0 ± 0.0
2.004GluAsn: 2.004 ± 1.505
4.008GluPro: 4.008 ± 2.364
4.008GluGln: 4.008 ± 2.364
2.004GluArg: 2.004 ± 1.182
0.0GluSer: 0.0 ± 0.0
4.008GluThr: 4.008 ± 0.323
2.004GluVal: 2.004 ± 1.182
0.0GluTrp: 0.0 ± 0.0
2.004GluTyr: 2.004 ± 1.505
0.0GluXaa: 0.0 ± 0.0
Phe
4.008PheAla: 4.008 ± 0.323
2.004PheCys: 2.004 ± 1.182
2.004PheAsp: 2.004 ± 1.182
6.012PheGlu: 6.012 ± 0.859
2.004PhePhe: 2.004 ± 1.182
0.0PheGly: 0.0 ± 0.0
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
4.008PheLys: 4.008 ± 3.011
2.004PheLeu: 2.004 ± 1.182
0.0PheMet: 0.0 ± 0.0
4.008PheAsn: 4.008 ± 0.323
0.0PhePro: 0.0 ± 0.0
2.004PheGln: 2.004 ± 1.505
8.016PheArg: 8.016 ± 3.334
2.004PheSer: 2.004 ± 1.182
8.016PheThr: 8.016 ± 2.041
2.004PheVal: 2.004 ± 1.505
0.0PheTrp: 0.0 ± 0.0
2.004PheTyr: 2.004 ± 1.182
0.0PheXaa: 0.0 ± 0.0
Gly
4.008GlyAla: 4.008 ± 3.011
0.0GlyCys: 0.0 ± 0.0
2.004GlyAsp: 2.004 ± 1.505
4.008GlyGlu: 4.008 ± 2.364
0.0GlyPhe: 0.0 ± 0.0
2.004GlyGly: 2.004 ± 1.182
0.0GlyHis: 0.0 ± 0.0
8.016GlyIle: 8.016 ± 4.729
2.004GlyLys: 2.004 ± 1.182
0.0GlyLeu: 0.0 ± 0.0
0.0GlyMet: 0.0 ± 0.0
2.004GlyAsn: 2.004 ± 1.505
2.004GlyPro: 2.004 ± 1.182
6.012GlyGln: 6.012 ± 0.859
6.012GlyArg: 6.012 ± 4.516
4.008GlySer: 4.008 ± 2.364
4.008GlyThr: 4.008 ± 0.323
4.008GlyVal: 4.008 ± 3.011
2.004GlyTrp: 2.004 ± 1.182
6.012GlyTyr: 6.012 ± 3.547
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
6.012HisIle: 6.012 ± 3.547
2.004HisLys: 2.004 ± 1.505
4.008HisLeu: 4.008 ± 2.364
0.0HisMet: 0.0 ± 0.0
2.004HisAsn: 2.004 ± 1.182
2.004HisPro: 2.004 ± 1.182
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.004HisTyr: 2.004 ± 1.505
0.0HisXaa: 0.0 ± 0.0
Ile
6.012IleAla: 6.012 ± 0.859
4.008IleCys: 4.008 ± 0.323
4.008IleAsp: 4.008 ± 0.323
2.004IleGlu: 2.004 ± 1.182
2.004IlePhe: 2.004 ± 1.182
0.0IleGly: 0.0 ± 0.0
2.004IleHis: 2.004 ± 1.182
4.008IleIle: 4.008 ± 0.323
12.024IleLys: 12.024 ± 7.093
2.004IleLeu: 2.004 ± 1.182
0.0IleMet: 0.0 ± 0.0
6.012IleAsn: 6.012 ± 1.829
2.004IlePro: 2.004 ± 1.505
2.004IleGln: 2.004 ± 1.182
2.004IleArg: 2.004 ± 1.182
2.004IleSer: 2.004 ± 1.182
10.02IleThr: 10.02 ± 2.152
4.008IleVal: 4.008 ± 0.323
2.004IleTrp: 2.004 ± 1.182
2.004IleTyr: 2.004 ± 1.182
0.0IleXaa: 0.0 ± 0.0
Lys
2.004LysAla: 2.004 ± 1.182
2.004LysCys: 2.004 ± 1.182
6.012LysAsp: 6.012 ± 0.859
2.004LysGlu: 2.004 ± 1.182
4.008LysPhe: 4.008 ± 2.364
4.008LysGly: 4.008 ± 2.364
6.012LysHis: 6.012 ± 0.859
4.008LysIle: 4.008 ± 0.323
2.004LysLys: 2.004 ± 1.182
6.012LysLeu: 6.012 ± 4.516
2.004LysMet: 2.004 ± 1.505
0.0LysAsn: 0.0 ± 0.0
10.02LysPro: 10.02 ± 2.152
2.004LysGln: 2.004 ± 1.182
2.004LysArg: 2.004 ± 1.505
4.008LysSer: 4.008 ± 2.364
2.004LysThr: 2.004 ± 1.505
6.012LysVal: 6.012 ± 1.829
0.0LysTrp: 0.0 ± 0.0
4.008LysTyr: 4.008 ± 2.364
0.0LysXaa: 0.0 ± 0.0
Leu
2.004LeuAla: 2.004 ± 1.505
2.004LeuCys: 2.004 ± 1.182
0.0LeuAsp: 0.0 ± 0.0
2.004LeuGlu: 2.004 ± 1.505
0.0LeuPhe: 0.0 ± 0.0
2.004LeuGly: 2.004 ± 1.505
2.004LeuHis: 2.004 ± 1.182
2.004LeuIle: 2.004 ± 1.182
4.008LeuLys: 4.008 ± 2.364
4.008LeuLeu: 4.008 ± 2.364
0.0LeuMet: 0.0 ± 0.0
4.008LeuAsn: 4.008 ± 0.323
4.008LeuPro: 4.008 ± 0.323
8.016LeuGln: 8.016 ± 2.041
8.016LeuArg: 8.016 ± 3.334
4.008LeuSer: 4.008 ± 0.323
4.008LeuThr: 4.008 ± 3.011
2.004LeuVal: 2.004 ± 1.182
0.0LeuTrp: 0.0 ± 0.0
2.004LeuTyr: 2.004 ± 1.182
0.0LeuXaa: 0.0 ± 0.0
Met
2.004MetAla: 2.004 ± 1.505
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
4.008MetGlu: 4.008 ± 0.323
0.0MetPhe: 0.0 ± 0.0
2.004MetGly: 2.004 ± 1.505
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.004MetLys: 2.004 ± 1.505
2.004MetLeu: 2.004 ± 1.505
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.004MetArg: 2.004 ± 1.505
4.008MetSer: 4.008 ± 0.323
0.0MetThr: 0.0 ± 0.0
2.004MetVal: 2.004 ± 1.182
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.008AsnAla: 4.008 ± 0.323
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
2.004AsnGlu: 2.004 ± 1.505
4.008AsnPhe: 4.008 ± 0.323
4.008AsnGly: 4.008 ± 2.364
0.0AsnHis: 0.0 ± 0.0
12.024AsnIle: 12.024 ± 9.032
2.004AsnLys: 2.004 ± 1.505
2.004AsnLeu: 2.004 ± 1.182
2.004AsnMet: 2.004 ± 1.505
10.02AsnAsn: 10.02 ± 0.536
2.004AsnPro: 2.004 ± 1.505
4.008AsnGln: 4.008 ± 0.323
2.004AsnArg: 2.004 ± 1.182
2.004AsnSer: 2.004 ± 1.505
6.012AsnThr: 6.012 ± 0.859
4.008AsnVal: 4.008 ± 0.323
0.0AsnTrp: 0.0 ± 0.0
6.012AsnTyr: 6.012 ± 3.547
0.0AsnXaa: 0.0 ± 0.0
Pro
2.004ProAla: 2.004 ± 1.505
0.0ProCys: 0.0 ± 0.0
2.004ProAsp: 2.004 ± 1.505
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
4.008ProGly: 4.008 ± 0.323
2.004ProHis: 2.004 ± 1.182
4.008ProIle: 4.008 ± 2.364
2.004ProLys: 2.004 ± 1.505
2.004ProLeu: 2.004 ± 1.505
0.0ProMet: 0.0 ± 0.0
4.008ProAsn: 4.008 ± 3.011
4.008ProPro: 4.008 ± 2.364
0.0ProGln: 0.0 ± 0.0
6.012ProArg: 6.012 ± 0.859
4.008ProSer: 4.008 ± 2.364
8.016ProThr: 8.016 ± 0.646
4.008ProVal: 4.008 ± 0.323
2.004ProTrp: 2.004 ± 1.505
2.004ProTyr: 2.004 ± 1.182
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
4.008GlnGlu: 4.008 ± 2.364
0.0GlnPhe: 0.0 ± 0.0
6.012GlnGly: 6.012 ± 0.859
0.0GlnHis: 0.0 ± 0.0
2.004GlnIle: 2.004 ± 1.182
0.0GlnLys: 0.0 ± 0.0
2.004GlnLeu: 2.004 ± 1.182
0.0GlnMet: 0.0 ± 0.0
6.012GlnAsn: 6.012 ± 1.829
4.008GlnPro: 4.008 ± 3.011
2.004GlnGln: 2.004 ± 1.182
2.004GlnArg: 2.004 ± 1.182
2.004GlnSer: 2.004 ± 1.182
4.008GlnThr: 4.008 ± 0.323
0.0GlnVal: 0.0 ± 0.0
2.004GlnTrp: 2.004 ± 1.182
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.008ArgAla: 4.008 ± 0.323
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
4.008ArgPhe: 4.008 ± 0.323
4.008ArgGly: 4.008 ± 2.364
0.0ArgHis: 0.0 ± 0.0
4.008ArgIle: 4.008 ± 0.323
8.016ArgLys: 8.016 ± 0.646
2.004ArgLeu: 2.004 ± 1.505
4.008ArgMet: 4.008 ± 0.323
6.012ArgAsn: 6.012 ± 1.829
0.0ArgPro: 0.0 ± 0.0
0.0ArgGln: 0.0 ± 0.0
24.048ArgArg: 24.048 ± 10.002
2.004ArgSer: 2.004 ± 1.505
4.008ArgThr: 4.008 ± 2.364
8.016ArgVal: 8.016 ± 6.022
0.0ArgTrp: 0.0 ± 0.0
10.02ArgTyr: 10.02 ± 0.536
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
4.008SerCys: 4.008 ± 0.323
2.004SerAsp: 2.004 ± 1.182
0.0SerGlu: 0.0 ± 0.0
4.008SerPhe: 4.008 ± 3.011
4.008SerGly: 4.008 ± 2.364
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
2.004SerLys: 2.004 ± 1.505
0.0SerLeu: 0.0 ± 0.0
4.008SerMet: 4.008 ± 1.188
6.012SerAsn: 6.012 ± 3.547
0.0SerPro: 0.0 ± 0.0
0.0SerGln: 0.0 ± 0.0
2.004SerArg: 2.004 ± 1.182
2.004SerSer: 2.004 ± 1.505
10.02SerThr: 10.02 ± 3.224
4.008SerVal: 4.008 ± 3.011
0.0SerTrp: 0.0 ± 0.0
2.004SerTyr: 2.004 ± 1.505
0.0SerXaa: 0.0 ± 0.0
Thr
4.008ThrAla: 4.008 ± 0.323
0.0ThrCys: 0.0 ± 0.0
6.012ThrAsp: 6.012 ± 0.859
6.012ThrGlu: 6.012 ± 0.859
4.008ThrPhe: 4.008 ± 0.323
4.008ThrGly: 4.008 ± 0.323
2.004ThrHis: 2.004 ± 1.182
4.008ThrIle: 4.008 ± 2.364
6.012ThrLys: 6.012 ± 1.829
8.016ThrLeu: 8.016 ± 0.646
4.008ThrMet: 4.008 ± 0.323
2.004ThrAsn: 2.004 ± 1.182
2.004ThrPro: 2.004 ± 1.182
0.0ThrGln: 0.0 ± 0.0
2.004ThrArg: 2.004 ± 1.182
8.016ThrSer: 8.016 ± 0.646
2.004ThrThr: 2.004 ± 1.505
8.016ThrVal: 8.016 ± 3.334
6.012ThrTrp: 6.012 ± 1.829
2.004ThrTyr: 2.004 ± 1.182
0.0ThrXaa: 0.0 ± 0.0
Val
4.008ValAla: 4.008 ± 3.011
0.0ValCys: 0.0 ± 0.0
4.008ValAsp: 4.008 ± 0.323
2.004ValGlu: 2.004 ± 1.505
0.0ValPhe: 0.0 ± 0.0
6.012ValGly: 6.012 ± 1.829
0.0ValHis: 0.0 ± 0.0
2.004ValIle: 2.004 ± 1.182
4.008ValLys: 4.008 ± 0.323
4.008ValLeu: 4.008 ± 0.323
0.0ValMet: 0.0 ± 1.027
2.004ValAsn: 2.004 ± 1.182
8.016ValPro: 8.016 ± 3.334
4.008ValGln: 4.008 ± 0.323
10.02ValArg: 10.02 ± 2.152
0.0ValSer: 0.0 ± 0.0
2.004ValThr: 2.004 ± 1.505
8.016ValVal: 8.016 ± 6.022
0.0ValTrp: 0.0 ± 0.0
4.008ValTyr: 4.008 ± 3.011
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.004TrpAsp: 2.004 ± 1.182
0.0TrpGlu: 0.0 ± 0.0
2.004TrpPhe: 2.004 ± 1.182
2.004TrpGly: 2.004 ± 1.182
2.004TrpHis: 2.004 ± 1.505
2.004TrpIle: 2.004 ± 1.182
2.004TrpLys: 2.004 ± 1.505
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.004TrpAsn: 2.004 ± 1.182
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.004TrpSer: 2.004 ± 1.505
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.004TrpTrp: 2.004 ± 1.182
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.004TyrAla: 2.004 ± 1.182
6.012TyrCys: 6.012 ± 1.829
2.004TyrAsp: 2.004 ± 1.182
6.012TyrGlu: 6.012 ± 3.547
4.008TyrPhe: 4.008 ± 0.323
6.012TyrGly: 6.012 ± 0.859
0.0TyrHis: 0.0 ± 0.0
4.008TyrIle: 4.008 ± 2.364
6.012TyrLys: 6.012 ± 3.547
2.004TyrLeu: 2.004 ± 1.505
0.0TyrMet: 0.0 ± 0.0
2.004TyrAsn: 2.004 ± 1.505
4.008TyrPro: 4.008 ± 2.364
0.0TyrGln: 0.0 ± 0.0
2.004TyrArg: 2.004 ± 1.505
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
4.008TyrVal: 4.008 ± 0.323
2.004TyrTrp: 2.004 ± 1.182
4.008TyrTyr: 4.008 ± 2.364
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (500 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski