Amino acid dipepetide frequency for Cladosporium fulvum T-1 virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.706AlaAla: 2.706 ± 1.004
0.541AlaCys: 0.541 ± 0.331
2.165AlaAsp: 2.165 ± 1.073
4.329AlaGlu: 4.329 ± 2.145
1.623AlaPhe: 1.623 ± 0.993
1.623AlaGly: 1.623 ± 0.832
0.541AlaHis: 0.541 ± 0.331
2.165AlaIle: 2.165 ± 1.324
3.247AlaLys: 3.247 ± 0.769
2.706AlaLeu: 2.706 ± 0.743
2.165AlaMet: 2.165 ± 0.716
2.165AlaAsn: 2.165 ± 1.426
4.87AlaPro: 4.87 ± 1.67
4.87AlaGln: 4.87 ± 0.901
5.411AlaArg: 5.411 ± 0.493
5.952AlaSer: 5.952 ± 1.433
3.788AlaThr: 3.788 ± 2.9
1.623AlaVal: 1.623 ± 0.832
0.541AlaTrp: 0.541 ± 0.522
2.165AlaTyr: 2.165 ± 1.324
0.0AlaXaa: 0.0 ± 0.0
Cys
0.541CysAla: 0.541 ± 0.331
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.082CysGlu: 1.082 ± 0.662
0.541CysPhe: 0.541 ± 0.522
0.541CysGly: 0.541 ± 0.522
0.541CysHis: 0.541 ± 0.522
0.541CysIle: 0.541 ± 0.331
0.541CysLys: 0.541 ± 0.331
0.541CysLeu: 0.541 ± 0.331
0.541CysMet: 0.541 ± 0.331
0.541CysAsn: 0.541 ± 0.331
0.0CysPro: 0.0 ± 0.0
2.165CysGln: 2.165 ± 1.073
0.541CysArg: 0.541 ± 0.522
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.623CysVal: 1.623 ± 0.993
0.0CysTrp: 0.0 ± 0.0
1.623CysTyr: 1.623 ± 1.531
0.0CysXaa: 0.0 ± 0.0
Asp
4.87AspAla: 4.87 ± 2.067
0.541AspCys: 0.541 ± 0.522
3.788AspAsp: 3.788 ± 2.9
3.788AspGlu: 3.788 ± 0.83
0.541AspPhe: 0.541 ± 0.331
5.411AspGly: 5.411 ± 1.487
1.623AspHis: 1.623 ± 1.375
3.247AspIle: 3.247 ± 0.901
5.411AspLys: 5.411 ± 3.6
3.247AspLeu: 3.247 ± 0.901
2.706AspMet: 2.706 ± 0.743
2.706AspAsn: 2.706 ± 1.86
3.247AspPro: 3.247 ± 1.075
1.082AspGln: 1.082 ± 1.424
4.87AspArg: 4.87 ± 2.291
3.247AspSer: 3.247 ± 1.816
3.788AspThr: 3.788 ± 1.518
3.788AspVal: 3.788 ± 1.641
1.623AspTrp: 1.623 ± 0.45
2.706AspTyr: 2.706 ± 0.743
0.0AspXaa: 0.0 ± 0.0
Glu
4.329GluAla: 4.329 ± 2.178
1.623GluCys: 1.623 ± 0.993
2.165GluAsp: 2.165 ± 1.343
8.658GluGlu: 8.658 ± 2.497
3.788GluPhe: 3.788 ± 0.83
3.247GluGly: 3.247 ± 1.072
1.623GluHis: 1.623 ± 0.45
3.247GluIle: 3.247 ± 0.901
3.247GluLys: 3.247 ± 1.072
5.952GluLeu: 5.952 ± 1.618
0.541GluMet: 0.541 ± 0.443
3.247GluAsn: 3.247 ± 2.595
5.411GluPro: 5.411 ± 3.542
5.411GluGln: 5.411 ± 1.577
5.952GluArg: 5.952 ± 0.961
5.952GluSer: 5.952 ± 3.963
5.952GluThr: 5.952 ± 0.166
3.788GluVal: 3.788 ± 1.215
1.623GluTrp: 1.623 ± 0.993
1.623GluTyr: 1.623 ± 0.832
0.0GluXaa: 0.0 ± 0.0
Phe
1.082PheAla: 1.082 ± 0.358
0.541PheCys: 0.541 ± 0.522
2.165PheAsp: 2.165 ± 1.343
3.247PheGlu: 3.247 ± 2.471
1.082PhePhe: 1.082 ± 1.424
0.541PheGly: 0.541 ± 0.522
2.165PheHis: 2.165 ± 2.805
3.247PheIle: 3.247 ± 1.726
1.623PheLys: 1.623 ± 0.45
3.788PheLeu: 3.788 ± 1.518
0.541PheMet: 0.541 ± 0.331
2.706PheAsn: 2.706 ± 1.86
1.623PhePro: 1.623 ± 0.993
1.082PheGln: 1.082 ± 1.424
2.165PheArg: 2.165 ± 1.324
0.541PheSer: 0.541 ± 0.331
1.623PheThr: 1.623 ± 0.45
1.623PheVal: 1.623 ± 0.45
0.0PheTrp: 0.0 ± 0.0
1.082PheTyr: 1.082 ± 0.358
0.0PheXaa: 0.0 ± 0.0
Gly
2.706GlyAla: 2.706 ± 0.743
1.082GlyCys: 1.082 ± 1.045
2.165GlyAsp: 2.165 ± 1.79
1.623GlyGlu: 1.623 ± 0.832
2.165GlyPhe: 2.165 ± 0.705
1.623GlyGly: 1.623 ± 0.832
3.247GlyHis: 3.247 ± 0.901
1.082GlyIle: 1.082 ± 0.662
6.494GlyLys: 6.494 ± 1.801
3.788GlyLeu: 3.788 ± 1.077
1.623GlyMet: 1.623 ± 0.45
1.082GlyAsn: 1.082 ± 0.358
3.788GlyPro: 3.788 ± 2.41
2.706GlyGln: 2.706 ± 1.02
2.706GlyArg: 2.706 ± 2.612
8.117GlySer: 8.117 ± 2.48
4.87GlyThr: 4.87 ± 1.351
2.165GlyVal: 2.165 ± 0.716
1.623GlyTrp: 1.623 ± 0.832
4.329GlyTyr: 4.329 ± 1.91
0.0GlyXaa: 0.0 ± 0.0
His
2.165HisAla: 2.165 ± 1.241
0.541HisCys: 0.541 ± 0.331
2.165HisAsp: 2.165 ± 1.324
2.165HisGlu: 2.165 ± 0.716
1.082HisPhe: 1.082 ± 1.402
2.165HisGly: 2.165 ± 0.716
1.082HisHis: 1.082 ± 0.662
2.165HisIle: 2.165 ± 1.073
3.788HisLys: 3.788 ± 2.317
2.706HisLeu: 2.706 ± 1.17
0.0HisMet: 0.0 ± 0.0
0.541HisAsn: 0.541 ± 0.331
2.165HisPro: 2.165 ± 1.426
0.541HisGln: 0.541 ± 0.331
1.623HisArg: 1.623 ± 0.832
0.541HisSer: 0.541 ± 0.522
1.082HisThr: 1.082 ± 0.662
1.082HisVal: 1.082 ± 1.424
1.623HisTrp: 1.623 ± 0.832
1.082HisTyr: 1.082 ± 0.358
0.0HisXaa: 0.0 ± 0.0
Ile
3.247IleAla: 3.247 ± 0.901
0.0IleCys: 0.0 ± 0.0
5.411IleAsp: 5.411 ± 0.493
2.706IleGlu: 2.706 ± 1.17
0.541IlePhe: 0.541 ± 0.522
2.706IleGly: 2.706 ± 1.17
1.623IleHis: 1.623 ± 1.217
1.623IleIle: 1.623 ± 0.45
3.247IleLys: 3.247 ± 1.986
3.247IleLeu: 3.247 ± 1.726
0.0IleMet: 0.0 ± 0.0
2.165IleAsn: 2.165 ± 1.426
2.706IlePro: 2.706 ± 1.004
4.329IleGln: 4.329 ± 1.176
4.329IleArg: 4.329 ± 1.965
2.165IleSer: 2.165 ± 1.426
2.706IleThr: 2.706 ± 1.655
2.165IleVal: 2.165 ± 1.324
0.0IleTrp: 0.0 ± 0.0
0.541IleTyr: 0.541 ± 0.331
0.0IleXaa: 0.0 ± 0.0
Lys
2.165LysAla: 2.165 ± 0.705
1.082LysCys: 1.082 ± 0.662
4.87LysAsp: 4.87 ± 1.703
8.658LysGlu: 8.658 ± 2.999
2.706LysPhe: 2.706 ± 0.743
4.329LysGly: 4.329 ± 2.482
2.165LysHis: 2.165 ± 0.705
4.87LysIle: 4.87 ± 1.985
3.788LysLys: 3.788 ± 2.41
5.952LysLeu: 5.952 ± 2.066
0.541LysMet: 0.541 ± 0.942
2.706LysAsn: 2.706 ± 1.118
3.247LysPro: 3.247 ± 2.38
1.623LysGln: 1.623 ± 1.375
2.165LysArg: 2.165 ± 1.324
3.247LysSer: 3.247 ± 1.665
6.494LysThr: 6.494 ± 1.733
2.706LysVal: 2.706 ± 4.213
2.165LysTrp: 2.165 ± 2.805
3.247LysTyr: 3.247 ± 1.072
0.0LysXaa: 0.0 ± 0.0
Leu
5.411LeuAla: 5.411 ± 1.942
0.541LeuCys: 0.541 ± 0.331
6.494LeuAsp: 6.494 ± 2.287
1.623LeuGlu: 1.623 ± 1.375
2.165LeuPhe: 2.165 ± 0.705
4.329LeuGly: 4.329 ± 1.176
1.082LeuHis: 1.082 ± 1.045
2.165LeuIle: 2.165 ± 0.705
4.87LeuLys: 4.87 ± 1.985
5.411LeuLeu: 5.411 ± 3.542
1.623LeuMet: 1.623 ± 0.832
1.623LeuAsn: 1.623 ± 0.993
4.329LeuPro: 4.329 ± 1.422
3.788LeuGln: 3.788 ± 1.518
8.117LeuArg: 8.117 ± 1.349
3.788LeuSer: 3.788 ± 1.641
8.117LeuThr: 8.117 ± 1.904
4.329LeuVal: 4.329 ± 1.422
0.0LeuTrp: 0.0 ± 0.0
2.706LeuTyr: 2.706 ± 1.17
0.0LeuXaa: 0.0 ± 0.0
Met
3.788MetAla: 3.788 ± 0.668
0.0MetCys: 0.0 ± 0.0
1.623MetAsp: 1.623 ± 0.45
2.165MetGlu: 2.165 ± 1.343
0.541MetPhe: 0.541 ± 0.331
1.082MetGly: 1.082 ± 0.662
0.0MetHis: 0.0 ± 0.0
2.165MetIle: 2.165 ± 0.716
0.541MetLys: 0.541 ± 0.522
1.623MetLeu: 1.623 ± 0.832
1.082MetMet: 1.082 ± 1.045
0.0MetAsn: 0.0 ± 0.0
1.623MetPro: 1.623 ± 0.45
1.082MetGln: 1.082 ± 0.358
1.623MetArg: 1.623 ± 0.45
1.082MetSer: 1.082 ± 0.662
2.165MetThr: 2.165 ± 0.716
2.165MetVal: 2.165 ± 1.343
0.541MetTrp: 0.541 ± 0.522
1.082MetTyr: 1.082 ± 1.045
0.0MetXaa: 0.0 ± 0.0
Asn
2.165AsnAla: 2.165 ± 0.705
0.541AsnCys: 0.541 ± 1.504
1.082AsnAsp: 1.082 ± 0.358
3.247AsnGlu: 3.247 ± 1.144
0.541AsnPhe: 0.541 ± 0.331
3.788AsnGly: 3.788 ± 1.518
1.082AsnHis: 1.082 ± 0.358
2.706AsnIle: 2.706 ± 1.655
1.082AsnLys: 1.082 ± 0.358
2.706AsnLeu: 2.706 ± 2.629
2.165AsnMet: 2.165 ± 2.09
1.082AsnAsn: 1.082 ± 0.662
1.623AsnPro: 1.623 ± 0.45
1.623AsnGln: 1.623 ± 0.832
3.788AsnArg: 3.788 ± 1.077
1.623AsnSer: 1.623 ± 0.832
1.623AsnThr: 1.623 ± 1.375
0.0AsnVal: 0.0 ± 0.0
1.082AsnTrp: 1.082 ± 0.662
3.247AsnTyr: 3.247 ± 1.072
0.0AsnXaa: 0.0 ± 0.0
Pro
3.247ProAla: 3.247 ± 1.726
1.082ProCys: 1.082 ± 1.402
1.623ProAsp: 1.623 ± 2.889
4.87ProGlu: 4.87 ± 0.329
2.165ProPhe: 2.165 ± 1.241
5.411ProGly: 5.411 ± 1.577
1.082ProHis: 1.082 ± 1.402
1.623ProIle: 1.623 ± 0.832
4.87ProLys: 4.87 ± 0.901
3.788ProLeu: 3.788 ± 0.668
2.165ProMet: 2.165 ± 0.705
0.541ProAsn: 0.541 ± 0.331
4.329ProPro: 4.329 ± 0.721
3.247ProGln: 3.247 ± 2.38
3.247ProArg: 3.247 ± 1.144
3.247ProSer: 3.247 ± 1.075
3.247ProThr: 3.247 ± 1.986
2.706ProVal: 2.706 ± 2.758
2.706ProTrp: 2.706 ± 1.004
0.541ProTyr: 0.541 ± 0.522
0.0ProXaa: 0.0 ± 0.0
Gln
2.706GlnAla: 2.706 ± 0.743
0.541GlnCys: 0.541 ± 0.331
5.411GlnAsp: 5.411 ± 0.493
5.411GlnGlu: 5.411 ± 4.296
2.706GlnPhe: 2.706 ± 0.978
2.165GlnGly: 2.165 ± 1.343
3.788GlnHis: 3.788 ± 1.077
0.541GlnIle: 0.541 ± 0.331
2.165GlnLys: 2.165 ± 1.79
2.706GlnLeu: 2.706 ± 1.02
3.247GlnMet: 3.247 ± 1.665
1.623GlnAsn: 1.623 ± 0.45
3.788GlnPro: 3.788 ± 1.518
1.623GlnGln: 1.623 ± 0.832
3.247GlnArg: 3.247 ± 0.769
1.623GlnSer: 1.623 ± 0.993
3.788GlnThr: 3.788 ± 2.782
3.247GlnVal: 3.247 ± 1.665
0.541GlnTrp: 0.541 ± 0.331
1.082GlnTyr: 1.082 ± 0.662
0.0GlnXaa: 0.0 ± 0.0
Arg
2.706ArgAla: 2.706 ± 2.147
0.0ArgCys: 0.0 ± 0.0
2.706ArgAsp: 2.706 ± 0.743
5.411ArgGlu: 5.411 ± 2.009
0.541ArgPhe: 0.541 ± 0.522
4.87ArgGly: 4.87 ± 3.202
3.788ArgHis: 3.788 ± 1.077
4.87ArgIle: 4.87 ± 1.67
5.952ArgLys: 5.952 ± 0.636
6.494ArgLeu: 6.494 ± 3.452
1.623ArgMet: 1.623 ± 0.832
3.788ArgAsn: 3.788 ± 1.518
2.165ArgPro: 2.165 ± 1.241
4.329ArgGln: 4.329 ± 3.841
9.74ArgArg: 9.74 ± 3.176
4.329ArgSer: 4.329 ± 1.422
7.035ArgThr: 7.035 ± 2.043
3.788ArgVal: 3.788 ± 2.173
0.541ArgTrp: 0.541 ± 0.331
3.788ArgTyr: 3.788 ± 1.215
0.0ArgXaa: 0.0 ± 0.0
Ser
2.165SerAla: 2.165 ± 0.705
1.623SerCys: 1.623 ± 0.832
4.87SerAsp: 4.87 ± 1.703
6.494SerGlu: 6.494 ± 0.674
2.706SerPhe: 2.706 ± 1.548
3.788SerGly: 3.788 ± 1.077
0.541SerHis: 0.541 ± 0.331
1.623SerIle: 1.623 ± 0.45
4.87SerLys: 4.87 ± 0.329
3.788SerLeu: 3.788 ± 1.135
1.082SerMet: 1.082 ± 0.976
3.247SerAsn: 3.247 ± 1.634
2.165SerPro: 2.165 ± 1.073
2.165SerGln: 2.165 ± 1.343
5.411SerArg: 5.411 ± 2.36
4.87SerSer: 4.87 ± 1.422
5.952SerThr: 5.952 ± 1.618
1.623SerVal: 1.623 ± 0.832
0.541SerTrp: 0.541 ± 0.522
0.541SerTyr: 0.541 ± 0.522
0.0SerXaa: 0.0 ± 0.0
Thr
4.87ThrAla: 4.87 ± 1.351
1.082ThrCys: 1.082 ± 0.358
4.87ThrAsp: 4.87 ± 1.703
5.952ThrGlu: 5.952 ± 1.773
2.706ThrPhe: 2.706 ± 1.17
4.87ThrGly: 4.87 ± 1.703
1.623ThrHis: 1.623 ± 0.45
3.788ThrIle: 3.788 ± 1.135
6.494ThrLys: 6.494 ± 4.279
7.035ThrLeu: 7.035 ± 2.022
1.082ThrMet: 1.082 ± 0.662
2.706ThrAsn: 2.706 ± 1.004
4.329ThrPro: 4.329 ± 0.538
2.706ThrGln: 2.706 ± 1.17
6.494ThrArg: 6.494 ± 2.143
3.788ThrSer: 3.788 ± 1.135
6.494ThrThr: 6.494 ± 2.114
2.706ThrVal: 2.706 ± 1.004
1.082ThrTrp: 1.082 ± 1.424
2.165ThrTyr: 2.165 ± 0.705
0.0ThrXaa: 0.0 ± 0.0
Val
1.623ValAla: 1.623 ± 0.993
0.541ValCys: 0.541 ± 0.331
3.788ValAsp: 3.788 ± 1.077
2.706ValGlu: 2.706 ± 0.978
3.247ValPhe: 3.247 ± 0.769
1.623ValGly: 1.623 ± 2.889
1.623ValHis: 1.623 ± 0.45
2.165ValIle: 2.165 ± 0.716
3.788ValLys: 3.788 ± 2.402
2.165ValLeu: 2.165 ± 1.324
1.623ValMet: 1.623 ± 0.45
2.165ValAsn: 2.165 ± 1.426
1.082ValPro: 1.082 ± 0.662
4.329ValGln: 4.329 ± 1.433
2.165ValArg: 2.165 ± 0.716
2.706ValSer: 2.706 ± 1.86
4.329ValThr: 4.329 ± 1.176
1.623ValVal: 1.623 ± 1.217
0.0ValTrp: 0.0 ± 0.0
1.623ValTyr: 1.623 ± 1.375
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.623TrpAsp: 1.623 ± 0.45
0.541TrpGlu: 0.541 ± 1.504
0.0TrpPhe: 0.0 ± 0.0
1.623TrpGly: 1.623 ± 0.45
0.0TrpHis: 0.0 ± 0.0
0.541TrpIle: 0.541 ± 0.331
2.165TrpLys: 2.165 ± 1.426
1.623TrpLeu: 1.623 ± 0.45
0.0TrpMet: 0.0 ± 0.0
0.541TrpAsn: 0.541 ± 0.522
1.082TrpPro: 1.082 ± 0.358
1.082TrpGln: 1.082 ± 0.358
2.165TrpArg: 2.165 ± 1.073
1.623TrpSer: 1.623 ± 0.45
0.541TrpThr: 0.541 ± 0.522
1.623TrpVal: 1.623 ± 0.832
0.0TrpTrp: 0.0 ± 0.0
0.541TrpTyr: 0.541 ± 0.331
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.706TyrAla: 2.706 ± 0.743
0.0TyrCys: 0.0 ± 0.0
3.247TyrAsp: 3.247 ± 1.144
2.706TyrGlu: 2.706 ± 1.17
1.082TyrPhe: 1.082 ± 0.358
3.247TyrGly: 3.247 ± 1.075
1.082TyrHis: 1.082 ± 0.662
1.082TyrIle: 1.082 ± 0.662
0.541TyrLys: 0.541 ± 0.331
3.247TyrLeu: 3.247 ± 2.433
1.082TyrMet: 1.082 ± 0.662
1.623TyrAsn: 1.623 ± 0.832
2.165TyrPro: 2.165 ± 1.073
2.165TyrGln: 2.165 ± 1.073
2.706TyrArg: 2.706 ± 1.02
2.165TyrSer: 2.165 ± 0.716
3.247TyrThr: 3.247 ± 0.901
0.541TyrVal: 0.541 ± 0.331
1.082TyrTrp: 1.082 ± 0.358
1.082TyrTyr: 1.082 ± 0.358
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1849 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski