Amino acid dipepetide frequency for Facklamia hominis CCUG 36813

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.951AlaAla: 4.951 ± 0.102
0.76AlaCys: 0.76 ± 0.037
4.128AlaAsp: 4.128 ± 0.086
3.799AlaGlu: 3.799 ± 0.087
3.285AlaPhe: 3.285 ± 0.08
4.991AlaGly: 4.991 ± 0.1
1.257AlaHis: 1.257 ± 0.044
6.037AlaIle: 6.037 ± 0.115
4.93AlaLys: 4.93 ± 0.101
8.146AlaLeu: 8.146 ± 0.133
2.193AlaMet: 2.193 ± 0.069
3.146AlaAsn: 3.146 ± 0.08
1.871AlaPro: 1.871 ± 0.065
3.459AlaGln: 3.459 ± 0.08
2.752AlaArg: 2.752 ± 0.083
4.924AlaSer: 4.924 ± 0.115
3.166AlaThr: 3.166 ± 0.077
4.57AlaVal: 4.57 ± 0.092
0.637AlaTrp: 0.637 ± 0.034
3.175AlaTyr: 3.175 ± 0.09
0.0AlaXaa: 0.0 ± 0.0
Cys
0.374CysAla: 0.374 ± 0.03
0.08CysCys: 0.08 ± 0.011
0.389CysAsp: 0.389 ± 0.027
0.308CysGlu: 0.308 ± 0.027
0.425CysPhe: 0.425 ± 0.026
0.566CysGly: 0.566 ± 0.034
0.262CysHis: 0.262 ± 0.025
0.438CysIle: 0.438 ± 0.031
0.271CysLys: 0.271 ± 0.023
1.075CysLeu: 1.075 ± 0.048
0.128CysMet: 0.128 ± 0.013
0.237CysAsn: 0.237 ± 0.034
0.317CysPro: 0.317 ± 0.025
0.633CysGln: 0.633 ± 0.032
0.311CysArg: 0.311 ± 0.024
0.346CysSer: 0.346 ± 0.025
0.219CysThr: 0.219 ± 0.019
0.405CysVal: 0.405 ± 0.026
0.056CysTrp: 0.056 ± 0.01
0.318CysTyr: 0.318 ± 0.026
0.0CysXaa: 0.0 ± 0.0
Asp
3.177AspAla: 3.177 ± 0.087
0.488AspCys: 0.488 ± 0.029
2.835AspAsp: 2.835 ± 0.087
4.101AspGlu: 4.101 ± 0.105
2.905AspPhe: 2.905 ± 0.072
3.173AspGly: 3.173 ± 0.108
1.813AspHis: 1.813 ± 0.065
3.716AspIle: 3.716 ± 0.088
3.475AspLys: 3.475 ± 0.09
7.119AspLeu: 7.119 ± 0.134
1.239AspMet: 1.239 ± 0.044
2.176AspAsn: 2.176 ± 0.06
2.818AspPro: 2.818 ± 0.083
5.152AspGln: 5.152 ± 0.146
2.934AspArg: 2.934 ± 0.08
3.305AspSer: 3.305 ± 0.077
2.287AspThr: 2.287 ± 0.065
3.055AspVal: 3.055 ± 0.083
0.716AspTrp: 0.716 ± 0.037
3.283AspTyr: 3.283 ± 0.086
0.0AspXaa: 0.0 ± 0.0
Glu
5.661GluAla: 5.661 ± 0.11
0.318GluCys: 0.318 ± 0.025
4.349GluAsp: 4.349 ± 0.12
5.981GluGlu: 5.981 ± 0.153
2.283GluPhe: 2.283 ± 0.068
3.976GluGly: 3.976 ± 0.089
1.011GluHis: 1.011 ± 0.042
4.975GluIle: 4.975 ± 0.105
4.694GluLys: 4.694 ± 0.117
6.558GluLeu: 6.558 ± 0.118
1.847GluMet: 1.847 ± 0.057
3.095GluAsn: 3.095 ± 0.08
1.672GluPro: 1.672 ± 0.062
2.529GluGln: 2.529 ± 0.079
3.001GluArg: 3.001 ± 0.087
4.103GluSer: 4.103 ± 0.102
3.079GluThr: 3.079 ± 0.088
4.702GluVal: 4.702 ± 0.121
0.649GluTrp: 0.649 ± 0.037
2.211GluTyr: 2.211 ± 0.057
0.0GluXaa: 0.0 ± 0.0
Phe
2.777PheAla: 2.777 ± 0.085
0.344PheCys: 0.344 ± 0.025
2.867PheAsp: 2.867 ± 0.071
2.764PheGlu: 2.764 ± 0.076
1.957PhePhe: 1.957 ± 0.064
2.605PheGly: 2.605 ± 0.072
0.762PheHis: 0.762 ± 0.037
3.405PheIle: 3.405 ± 0.104
2.679PheLys: 2.679 ± 0.06
4.135PheLeu: 4.135 ± 0.105
1.181PheMet: 1.181 ± 0.048
2.227PheAsn: 2.227 ± 0.067
1.386PhePro: 1.386 ± 0.052
1.706PheGln: 1.706 ± 0.064
1.386PheArg: 1.386 ± 0.05
3.079PheSer: 3.079 ± 0.086
2.068PheThr: 2.068 ± 0.067
2.757PheVal: 2.757 ± 0.082
0.378PheTrp: 0.378 ± 0.029
1.847PheTyr: 1.847 ± 0.059
0.0PheXaa: 0.0 ± 0.0
Gly
4.029GlyAla: 4.029 ± 0.104
0.476GlyCys: 0.476 ± 0.03
3.135GlyAsp: 3.135 ± 0.081
3.515GlyGlu: 3.515 ± 0.099
2.851GlyPhe: 2.851 ± 0.081
3.976GlyGly: 3.976 ± 0.109
1.46GlyHis: 1.46 ± 0.056
4.941GlyIle: 4.941 ± 0.097
4.119GlyLys: 4.119 ± 0.108
6.773GlyLeu: 6.773 ± 0.131
1.767GlyMet: 1.767 ± 0.053
2.316GlyAsn: 2.316 ± 0.082
1.644GlyPro: 1.644 ± 0.057
3.862GlyGln: 3.862 ± 0.129
2.788GlyArg: 2.788 ± 0.073
3.879GlySer: 3.879 ± 0.094
3.043GlyThr: 3.043 ± 0.081
4.3GlyVal: 4.3 ± 0.09
0.581GlyTrp: 0.581 ± 0.035
2.708GlyTyr: 2.708 ± 0.064
0.0GlyXaa: 0.0 ± 0.0
His
1.12HisAla: 1.12 ± 0.042
0.237HisCys: 0.237 ± 0.02
1.064HisAsp: 1.064 ± 0.043
1.142HisGlu: 1.142 ± 0.047
1.254HisPhe: 1.254 ± 0.051
1.078HisGly: 1.078 ± 0.044
0.707HisHis: 0.707 ± 0.037
1.33HisIle: 1.33 ± 0.046
0.908HisLys: 0.908 ± 0.039
2.357HisLeu: 2.357 ± 0.062
0.445HisMet: 0.445 ± 0.028
0.664HisAsn: 0.664 ± 0.035
1.179HisPro: 1.179 ± 0.05
1.549HisGln: 1.549 ± 0.059
0.95HisArg: 0.95 ± 0.052
1.19HisSer: 1.19 ± 0.047
0.912HisThr: 0.912 ± 0.046
1.123HisVal: 1.123 ± 0.05
0.242HisTrp: 0.242 ± 0.02
1.172HisTyr: 1.172 ± 0.057
0.0HisXaa: 0.0 ± 0.0
Ile
5.595IleAla: 5.595 ± 0.118
0.637IleCys: 0.637 ± 0.034
5.089IleAsp: 5.089 ± 0.088
5.297IleGlu: 5.297 ± 0.124
2.987IlePhe: 2.987 ± 0.106
4.613IleGly: 4.613 ± 0.1
1.635IleHis: 1.635 ± 0.057
5.165IleIle: 5.165 ± 0.134
4.465IleLys: 4.465 ± 0.103
7.479IleLeu: 7.479 ± 0.162
1.572IleMet: 1.572 ± 0.052
3.435IleAsn: 3.435 ± 0.092
3.101IlePro: 3.101 ± 0.069
3.718IleGln: 3.718 ± 0.092
3.103IleArg: 3.103 ± 0.076
4.485IleSer: 4.485 ± 0.114
3.502IleThr: 3.502 ± 0.097
4.718IleVal: 4.718 ± 0.117
0.581IleTrp: 0.581 ± 0.036
2.898IleTyr: 2.898 ± 0.077
0.0IleXaa: 0.0 ± 0.0
Lys
4.774LysAla: 4.774 ± 0.122
0.246LysCys: 0.246 ± 0.024
4.394LysAsp: 4.394 ± 0.108
5.836LysGlu: 5.836 ± 0.13
1.663LysPhe: 1.663 ± 0.065
3.803LysGly: 3.803 ± 0.089
1.058LysHis: 1.058 ± 0.04
4.42LysIle: 4.42 ± 0.109
4.465LysLys: 4.465 ± 0.106
5.317LysLeu: 5.317 ± 0.1
1.78LysMet: 1.78 ± 0.058
3.184LysAsn: 3.184 ± 0.089
1.981LysPro: 1.981 ± 0.09
3.017LysGln: 3.017 ± 0.084
2.686LysArg: 2.686 ± 0.071
3.444LysSer: 3.444 ± 0.086
3.368LysThr: 3.368 ± 0.091
4.28LysVal: 4.28 ± 0.122
0.55LysTrp: 0.55 ± 0.033
2.209LysTyr: 2.209 ± 0.072
0.0LysXaa: 0.0 ± 0.0
Leu
9.038LeuAla: 9.038 ± 0.156
0.749LeuCys: 0.749 ± 0.039
6.603LeuAsp: 6.603 ± 0.123
6.809LeuGlu: 6.809 ± 0.121
4.347LeuPhe: 4.347 ± 0.116
6.447LeuGly: 6.447 ± 0.125
1.558LeuHis: 1.558 ± 0.059
7.944LeuIle: 7.944 ± 0.157
7.11LeuLys: 7.11 ± 0.125
10.729LeuLeu: 10.729 ± 0.206
2.876LeuMet: 2.876 ± 0.085
4.955LeuAsn: 4.955 ± 0.111
3.904LeuPro: 3.904 ± 0.09
3.913LeuGln: 3.913 ± 0.104
3.846LeuArg: 3.846 ± 0.101
7.678LeuSer: 7.678 ± 0.151
5.823LeuThr: 5.823 ± 0.1
6.818LeuVal: 6.818 ± 0.116
0.827LeuTrp: 0.827 ± 0.041
3.367LeuTyr: 3.367 ± 0.091
0.0LeuXaa: 0.0 ± 0.0
Met
2.196MetAla: 2.196 ± 0.068
0.118MetCys: 0.118 ± 0.015
1.673MetAsp: 1.673 ± 0.059
1.529MetGlu: 1.529 ± 0.055
0.657MetPhe: 0.657 ± 0.035
1.742MetGly: 1.742 ± 0.058
0.4MetHis: 0.4 ± 0.025
2.091MetIle: 2.091 ± 0.068
1.961MetLys: 1.961 ± 0.054
2.062MetLeu: 2.062 ± 0.068
0.747MetMet: 0.747 ± 0.038
1.445MetAsn: 1.445 ± 0.053
0.946MetPro: 0.946 ± 0.039
0.943MetGln: 0.943 ± 0.043
1.076MetArg: 1.076 ± 0.053
1.549MetSer: 1.549 ± 0.05
1.896MetThr: 1.896 ± 0.059
1.798MetVal: 1.798 ± 0.061
0.107MetTrp: 0.107 ± 0.014
0.611MetTyr: 0.611 ± 0.03
0.0MetXaa: 0.0 ± 0.0
Asn
2.636AsnAla: 2.636 ± 0.069
0.284AsnCys: 0.284 ± 0.027
2.383AsnAsp: 2.383 ± 0.067
2.952AsnGlu: 2.952 ± 0.07
2.021AsnPhe: 2.021 ± 0.066
2.683AsnGly: 2.683 ± 0.075
1.228AsnHis: 1.228 ± 0.047
2.88AsnIle: 2.88 ± 0.087
2.755AsnLys: 2.755 ± 0.083
4.495AsnLeu: 4.495 ± 0.101
0.97AsnMet: 0.97 ± 0.047
1.932AsnAsn: 1.932 ± 0.075
2.27AsnPro: 2.27 ± 0.074
3.345AsnGln: 3.345 ± 0.083
2.133AsnArg: 2.133 ± 0.054
2.243AsnSer: 2.243 ± 0.091
1.854AsnThr: 1.854 ± 0.073
2.276AsnVal: 2.276 ± 0.065
0.512AsnTrp: 0.512 ± 0.031
2.023AsnTyr: 2.023 ± 0.062
0.0AsnXaa: 0.0 ± 0.0
Pro
2.408ProAla: 2.408 ± 0.066
0.192ProCys: 0.192 ± 0.019
2.146ProAsp: 2.146 ± 0.064
2.809ProGlu: 2.809 ± 0.087
1.644ProPhe: 1.644 ± 0.053
2.229ProGly: 2.229 ± 0.087
0.753ProHis: 0.753 ± 0.038
2.757ProIle: 2.757 ± 0.07
2.122ProLys: 2.122 ± 0.077
3.468ProLeu: 3.468 ± 0.077
0.857ProMet: 0.857 ± 0.036
1.663ProAsn: 1.663 ± 0.064
0.682ProPro: 0.682 ± 0.039
1.825ProGln: 1.825 ± 0.058
1.174ProArg: 1.174 ± 0.046
2.654ProSer: 2.654 ± 0.076
1.862ProThr: 1.862 ± 0.062
2.471ProVal: 2.471 ± 0.074
0.293ProTrp: 0.293 ± 0.025
1.511ProTyr: 1.511 ± 0.051
0.0ProXaa: 0.0 ± 0.0
Gln
5.941GlnAla: 5.941 ± 0.145
0.248GlnCys: 0.248 ± 0.019
2.833GlnAsp: 2.833 ± 0.069
4.183GlnGlu: 4.183 ± 0.098
1.816GlnPhe: 1.816 ± 0.06
3.173GlnGly: 3.173 ± 0.089
0.832GlnHis: 0.832 ± 0.037
3.681GlnIle: 3.681 ± 0.089
3.157GlnLys: 3.157 ± 0.105
5.635GlnLeu: 5.635 ± 0.13
1.355GlnMet: 1.355 ± 0.047
1.802GlnAsn: 1.802 ± 0.052
1.601GlnPro: 1.601 ± 0.083
2.146GlnGln: 2.146 ± 0.069
2.231GlnArg: 2.231 ± 0.077
3.694GlnSer: 3.694 ± 0.109
2.674GlnThr: 2.674 ± 0.072
4.414GlnVal: 4.414 ± 0.099
0.539GlnTrp: 0.539 ± 0.03
1.563GlnTyr: 1.563 ± 0.059
0.0GlnXaa: 0.0 ± 0.0
Arg
2.413ArgAla: 2.413 ± 0.067
0.27ArgCys: 0.27 ± 0.023
2.062ArgAsp: 2.062 ± 0.063
2.491ArgGlu: 2.491 ± 0.078
1.95ArgPhe: 1.95 ± 0.065
2.194ArgGly: 2.194 ± 0.069
0.952ArgHis: 0.952 ± 0.04
3.283ArgIle: 3.283 ± 0.075
2.656ArgLys: 2.656 ± 0.08
4.98ArgLeu: 4.98 ± 0.108
1.208ArgMet: 1.208 ± 0.048
1.498ArgAsn: 1.498 ± 0.051
1.596ArgPro: 1.596 ± 0.053
2.701ArgGln: 2.701 ± 0.073
2.153ArgArg: 2.153 ± 0.076
2.652ArgSer: 2.652 ± 0.066
1.829ArgThr: 1.829 ± 0.055
2.62ArgVal: 2.62 ± 0.076
0.362ArgTrp: 0.362 ± 0.029
1.889ArgTyr: 1.889 ± 0.055
0.0ArgXaa: 0.0 ± 0.0
Ser
3.681SerAla: 3.681 ± 0.089
0.394SerCys: 0.394 ± 0.029
3.555SerAsp: 3.555 ± 0.096
3.589SerGlu: 3.589 ± 0.084
3.13SerPhe: 3.13 ± 0.09
4.192SerGly: 4.192 ± 0.097
1.454SerHis: 1.454 ± 0.056
4.613SerIle: 4.613 ± 0.107
3.984SerLys: 3.984 ± 0.098
7.455SerLeu: 7.455 ± 0.155
1.693SerMet: 1.693 ± 0.056
2.878SerAsn: 2.878 ± 0.072
2.225SerPro: 2.225 ± 0.066
3.936SerGln: 3.936 ± 0.101
2.417SerArg: 2.417 ± 0.075
4.114SerSer: 4.114 ± 0.117
3.113SerThr: 3.113 ± 0.107
3.835SerVal: 3.835 ± 0.085
0.657SerTrp: 0.657 ± 0.038
2.706SerTyr: 2.706 ± 0.077
0.0SerXaa: 0.0 ± 0.0
Thr
3.499ThrAla: 3.499 ± 0.084
0.398ThrCys: 0.398 ± 0.029
2.844ThrAsp: 2.844 ± 0.076
2.515ThrGlu: 2.515 ± 0.092
1.994ThrPhe: 1.994 ± 0.065
3.633ThrGly: 3.633 ± 0.086
1.053ThrHis: 1.053 ± 0.041
4.011ThrIle: 4.011 ± 0.115
2.565ThrLys: 2.565 ± 0.083
5.252ThrLeu: 5.252 ± 0.116
1.078ThrMet: 1.078 ± 0.048
2.127ThrAsn: 2.127 ± 0.07
2.184ThrPro: 2.184 ± 0.064
2.44ThrGln: 2.44 ± 0.071
1.887ThrArg: 1.887 ± 0.062
3.249ThrSer: 3.249 ± 0.098
2.596ThrThr: 2.596 ± 0.116
3.367ThrVal: 3.367 ± 0.102
0.47ThrTrp: 0.47 ± 0.034
2.084ThrTyr: 2.084 ± 0.069
0.0ThrXaa: 0.0 ± 0.0
Val
4.798ValAla: 4.798 ± 0.104
0.492ValCys: 0.492 ± 0.03
4.418ValAsp: 4.418 ± 0.088
4.347ValGlu: 4.347 ± 0.103
2.793ValPhe: 2.793 ± 0.077
4.172ValGly: 4.172 ± 0.103
1.131ValHis: 1.131 ± 0.05
5.138ValIle: 5.138 ± 0.112
3.996ValLys: 3.996 ± 0.089
6.239ValLeu: 6.239 ± 0.137
1.673ValMet: 1.673 ± 0.057
3.043ValAsn: 3.043 ± 0.073
2.189ValPro: 2.189 ± 0.064
2.632ValGln: 2.632 ± 0.08
2.363ValArg: 2.363 ± 0.065
4.202ValSer: 4.202 ± 0.095
3.66ValThr: 3.66 ± 0.1
4.362ValVal: 4.362 ± 0.104
0.534ValTrp: 0.534 ± 0.036
2.458ValTyr: 2.458 ± 0.058
0.0ValXaa: 0.0 ± 0.0
Trp
0.579TrpAla: 0.579 ± 0.031
0.047TrpCys: 0.047 ± 0.009
0.514TrpAsp: 0.514 ± 0.033
0.499TrpGlu: 0.499 ± 0.032
0.34TrpPhe: 0.34 ± 0.024
0.526TrpGly: 0.526 ± 0.035
0.186TrpHis: 0.186 ± 0.017
0.762TrpIle: 0.762 ± 0.039
0.474TrpLys: 0.474 ± 0.03
1.183TrpLeu: 1.183 ± 0.046
0.284TrpMet: 0.284 ± 0.022
0.387TrpAsn: 0.387 ± 0.031
0.289TrpPro: 0.289 ± 0.022
0.72TrpGln: 0.72 ± 0.039
0.422TrpArg: 0.422 ± 0.029
0.516TrpSer: 0.516 ± 0.03
0.452TrpThr: 0.452 ± 0.033
0.619TrpVal: 0.619 ± 0.037
0.089TrpTrp: 0.089 ± 0.015
0.295TrpTyr: 0.295 ± 0.025
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.529TyrAla: 2.529 ± 0.074
0.382TyrCys: 0.382 ± 0.028
2.491TyrAsp: 2.491 ± 0.074
2.229TyrGlu: 2.229 ± 0.07
2.008TyrPhe: 2.008 ± 0.067
2.39TyrGly: 2.39 ± 0.062
1.111TyrHis: 1.111 ± 0.05
2.489TyrIle: 2.489 ± 0.068
1.69TyrLys: 1.69 ± 0.058
4.883TyrLeu: 4.883 ± 0.109
0.649TyrMet: 0.649 ± 0.031
1.664TyrAsn: 1.664 ± 0.054
1.664TyrPro: 1.664 ± 0.065
3.291TyrGln: 3.291 ± 0.098
2.147TyrArg: 2.147 ± 0.064
2.317TyrSer: 2.317 ± 0.074
1.842TyrThr: 1.842 ± 0.071
2.149TyrVal: 2.149 ± 0.069
0.403TyrTrp: 0.403 ± 0.031
1.985TyrTyr: 1.985 ± 0.072
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1717 proteins (552778 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski