Amino acid dipepetide frequency for Cladophialophora immunda

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.163AlaAla: 9.163 ± 0.053	1.155AlaCys: 1.155 ± 0.012	4.334AlaAsp: 4.334 ± 0.026	5.25AlaGlu: 5.25 ± 0.038	3.227AlaPhe: 3.227 ± 0.024	5.901AlaGly: 5.901 ± 0.036	1.85AlaHis: 1.85 ± 0.017	4.261AlaIle: 4.261 ± 0.03	3.92AlaLys: 3.92 ± 0.028	7.907AlaLeu: 7.907 ± 0.043	1.988AlaMet: 1.988 ± 0.017	2.897AlaAsn: 2.897 ± 0.02	4.587AlaPro: 4.587 ± 0.034	3.622AlaGln: 3.622 ± 0.025	5.245AlaArg: 5.245 ± 0.032	7.205AlaSer: 7.205 ± 0.033	5.411AlaThr: 5.411 ± 0.032	5.463AlaVal: 5.463 ± 0.036	1.182AlaTrp: 1.182 ± 0.014	2.171AlaTyr: 2.171 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.019CysAla: 1.019 ± 0.013	0.264CysCys: 0.264 ± 0.008	0.703CysAsp: 0.703 ± 0.009	0.62CysGlu: 0.62 ± 0.008	0.589CysPhe: 0.589 ± 0.009	0.93CysGly: 0.93 ± 0.013	0.358CysHis: 0.358 ± 0.008	0.703CysIle: 0.703 ± 0.011	0.498CysLys: 0.498 ± 0.009	1.386CysLeu: 1.386 ± 0.018	0.276CysMet: 0.276 ± 0.007	0.418CysAsn: 0.418 ± 0.008	0.694CysPro: 0.694 ± 0.012	0.488CysGln: 0.488 ± 0.009	0.873CysArg: 0.873 ± 0.011	0.956CysSer: 0.956 ± 0.015	0.719CysThr: 0.719 ± 0.011	0.849CysVal: 0.849 ± 0.012	0.222CysTrp: 0.222 ± 0.006	0.39CysTyr: 0.39 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.691AspAla: 4.691 ± 0.028	0.661AspCys: 0.661 ± 0.011	4.151AspAsp: 4.151 ± 0.037	4.43AspGlu: 4.43 ± 0.034	2.292AspPhe: 2.292 ± 0.018	3.982AspGly: 3.982 ± 0.026	1.354AspHis: 1.354 ± 0.014	2.925AspIle: 2.925 ± 0.022	2.306AspLys: 2.306 ± 0.022	5.238AspLeu: 5.238 ± 0.027	1.256AspMet: 1.256 ± 0.013	1.801AspAsn: 1.801 ± 0.018	3.484AspPro: 3.484 ± 0.026	2.057AspGln: 2.057 ± 0.02	3.225AspArg: 3.225 ± 0.024	3.964AspSer: 3.964 ± 0.027	2.939AspThr: 2.939 ± 0.025	3.71AspVal: 3.71 ± 0.025	0.91AspTrp: 0.91 ± 0.012	1.538AspTyr: 1.538 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.383GluAla: 5.383 ± 0.033	0.652GluCys: 0.652 ± 0.012	4.173GluAsp: 4.173 ± 0.036	5.225GluGlu: 5.225 ± 0.053	1.869GluPhe: 1.869 ± 0.016	3.694GluGly: 3.694 ± 0.028	1.464GluHis: 1.464 ± 0.016	3.106GluIle: 3.106 ± 0.023	3.548GluLys: 3.548 ± 0.029	5.182GluLeu: 5.182 ± 0.037	1.481GluMet: 1.481 ± 0.013	2.159GluAsn: 2.159 ± 0.021	2.801GluPro: 2.801 ± 0.032	2.593GluGln: 2.593 ± 0.022	4.017GluArg: 4.017 ± 0.031	4.202GluSer: 4.202 ± 0.027	3.428GluThr: 3.428 ± 0.024	3.573GluVal: 3.573 ± 0.027	0.865GluTrp: 0.865 ± 0.012	1.601GluTyr: 1.601 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.113PheAla: 3.113 ± 0.023	0.597PheCys: 0.597 ± 0.01	2.358PheAsp: 2.358 ± 0.024	2.205PheGlu: 2.205 ± 0.021	1.628PhePhe: 1.628 ± 0.019	2.847PheGly: 2.847 ± 0.026	0.936PheHis: 0.936 ± 0.014	1.719PheIle: 1.719 ± 0.019	1.401PheLys: 1.401 ± 0.016	3.566PheLeu: 3.566 ± 0.026	0.777PheMet: 0.777 ± 0.011	1.346PheAsn: 1.346 ± 0.016	1.986PhePro: 1.986 ± 0.017	1.473PheGln: 1.473 ± 0.014	2.02PheArg: 2.02 ± 0.018	2.926PheSer: 2.926 ± 0.023	2.048PheThr: 2.048 ± 0.02	2.463PheVal: 2.463 ± 0.019	0.687PheTrp: 0.687 ± 0.01	1.097PheTyr: 1.097 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.321GlyAla: 5.321 ± 0.036	0.88GlyCys: 0.88 ± 0.012	3.541GlyAsp: 3.541 ± 0.026	3.602GlyGlu: 3.602 ± 0.026	2.817GlyPhe: 2.817 ± 0.027	5.612GlyGly: 5.612 ± 0.052	1.746GlyHis: 1.746 ± 0.019	3.407GlyIle: 3.407 ± 0.025	3.298GlyLys: 3.298 ± 0.027	6.089GlyLeu: 6.089 ± 0.036	1.626GlyMet: 1.626 ± 0.014	2.346GlyAsn: 2.346 ± 0.019	3.386GlyPro: 3.386 ± 0.029	2.697GlyGln: 2.697 ± 0.022	4.281GlyArg: 4.281 ± 0.033	5.473GlySer: 5.473 ± 0.032	3.987GlyThr: 3.987 ± 0.028	4.327GlyVal: 4.327 ± 0.03	1.165GlyTrp: 1.165 ± 0.014	2.086GlyTyr: 2.086 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.961HisAla: 1.961 ± 0.018	0.351HisCys: 0.351 ± 0.007	1.402HisAsp: 1.402 ± 0.015	1.419HisGlu: 1.419 ± 0.016	0.976HisPhe: 0.976 ± 0.012	1.823HisGly: 1.823 ± 0.019	0.925HisHis: 0.925 ± 0.014	1.216HisIle: 1.216 ± 0.013	0.944HisLys: 0.944 ± 0.013	2.375HisLeu: 2.375 ± 0.021	0.511HisMet: 0.511 ± 0.009	0.819HisAsn: 0.819 ± 0.013	1.774HisPro: 1.774 ± 0.019	1.046HisGln: 1.046 ± 0.014	1.652HisArg: 1.652 ± 0.016	1.89HisSer: 1.89 ± 0.017	1.29HisThr: 1.29 ± 0.015	1.501HisVal: 1.501 ± 0.015	0.36HisTrp: 0.36 ± 0.007	0.709HisTyr: 0.709 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.148IleAla: 4.148 ± 0.028	0.806IleCys: 0.806 ± 0.013	2.8IleAsp: 2.8 ± 0.022	2.77IleGlu: 2.77 ± 0.023	1.967IlePhe: 1.967 ± 0.019	3.091IleGly: 3.091 ± 0.024	1.234IleHis: 1.234 ± 0.015	2.342IleIle: 2.342 ± 0.024	2.026IleLys: 2.026 ± 0.02	4.624IleLeu: 4.624 ± 0.032	0.973IleMet: 0.973 ± 0.012	1.712IleAsn: 1.712 ± 0.016	3.025IlePro: 3.025 ± 0.021	1.949IleGln: 1.949 ± 0.018	2.773IleArg: 2.773 ± 0.023	3.78IleSer: 3.78 ± 0.024	2.668IleThr: 2.668 ± 0.021	3.121IleVal: 3.121 ± 0.022	0.741IleTrp: 0.741 ± 0.012	1.406IleTyr: 1.406 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.103LysAla: 4.103 ± 0.029	0.522LysCys: 0.522 ± 0.009	2.721LysAsp: 2.721 ± 0.024	3.185LysGlu: 3.185 ± 0.028	1.394LysPhe: 1.394 ± 0.015	2.848LysGly: 2.848 ± 0.024	1.142LysHis: 1.142 ± 0.013	2.257LysIle: 2.257 ± 0.02	2.93LysLys: 2.93 ± 0.04	3.883LysLeu: 3.883 ± 0.028	1.025LysMet: 1.025 ± 0.013	1.538LysAsn: 1.538 ± 0.015	2.618LysPro: 2.618 ± 0.025	1.827LysGln: 1.827 ± 0.019	3.359LysArg: 3.359 ± 0.025	3.404LysSer: 3.404 ± 0.029	2.701LysThr: 2.701 ± 0.022	2.751LysVal: 2.751 ± 0.021	0.672LysTrp: 0.672 ± 0.011	1.345LysTyr: 1.345 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.02LeuAla: 8.02 ± 0.04	1.347LeuCys: 1.347 ± 0.016	5.348LeuAsp: 5.348 ± 0.034	5.639LeuGlu: 5.639 ± 0.035	3.372LeuPhe: 3.372 ± 0.028	5.995LeuGly: 5.995 ± 0.038	2.374LeuHis: 2.374 ± 0.021	3.87LeuIle: 3.87 ± 0.028	4.165LeuLys: 4.165 ± 0.03	8.662LeuLeu: 8.662 ± 0.058	1.792LeuMet: 1.792 ± 0.017	3.121LeuAsn: 3.121 ± 0.023	5.571LeuPro: 5.571 ± 0.034	4.011LeuGln: 4.011 ± 0.028	6.003LeuArg: 6.003 ± 0.033	7.358LeuSer: 7.358 ± 0.037	4.851LeuThr: 4.851 ± 0.03	5.471LeuVal: 5.471 ± 0.029	1.284LeuTrp: 1.284 ± 0.017	2.365LeuTyr: 2.365 ± 0.018	0.0LeuXaa: 0.0 ± 0.0
Met	2.27MetAla: 2.27 ± 0.018	0.255MetCys: 0.255 ± 0.006	1.217MetAsp: 1.217 ± 0.012	1.218MetGlu: 1.218 ± 0.016	0.746MetPhe: 0.746 ± 0.01	1.478MetGly: 1.478 ± 0.017	0.488MetHis: 0.488 ± 0.008	0.976MetIle: 0.976 ± 0.012	0.96MetLys: 0.96 ± 0.013	1.935MetLeu: 1.935 ± 0.019	0.561MetMet: 0.561 ± 0.011	0.772MetAsn: 0.772 ± 0.011	1.287MetPro: 1.287 ± 0.017	0.888MetGln: 0.888 ± 0.013	1.265MetArg: 1.265 ± 0.015	1.891MetSer: 1.891 ± 0.016	1.338MetThr: 1.338 ± 0.014	1.339MetVal: 1.339 ± 0.014	0.259MetTrp: 0.259 ± 0.007	0.525MetTyr: 0.525 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.113AsnAla: 3.113 ± 0.022	0.437AsnCys: 0.437 ± 0.008	1.863AsnAsp: 1.863 ± 0.019	1.897AsnGlu: 1.897 ± 0.018	1.336AsnPhe: 1.336 ± 0.016	2.831AsnGly: 2.831 ± 0.025	0.883AsnHis: 0.883 ± 0.011	1.904AsnIle: 1.904 ± 0.018	1.412AsnLys: 1.412 ± 0.015	3.229AsnLeu: 3.229 ± 0.02	0.775AsnMet: 0.775 ± 0.012	1.365AsnAsn: 1.365 ± 0.019	2.409AsnPro: 2.409 ± 0.021	1.305AsnGln: 1.305 ± 0.013	1.879AsnArg: 1.879 ± 0.018	2.576AsnSer: 2.576 ± 0.018	2.052AsnThr: 2.052 ± 0.019	2.326AsnVal: 2.326 ± 0.019	0.542AsnTrp: 0.542 ± 0.009	0.984AsnTyr: 0.984 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	5.199ProAla: 5.199 ± 0.037	0.565ProCys: 0.565 ± 0.011	3.326ProAsp: 3.326 ± 0.026	3.791ProGlu: 3.791 ± 0.031	2.082ProPhe: 2.082 ± 0.018	4.023ProGly: 4.023 ± 0.031	1.368ProHis: 1.368 ± 0.015	2.472ProIle: 2.472 ± 0.022	2.561ProLys: 2.561 ± 0.021	4.907ProLeu: 4.907 ± 0.031	1.098ProMet: 1.098 ± 0.014	2.181ProAsn: 2.181 ± 0.021	5.331ProPro: 5.331 ± 0.061	2.636ProGln: 2.636 ± 0.028	3.609ProArg: 3.609 ± 0.023	6.058ProSer: 6.058 ± 0.039	4.04ProThr: 4.04 ± 0.027	3.55ProVal: 3.55 ± 0.025	0.776ProTrp: 0.776 ± 0.012	1.515ProTyr: 1.515 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.643GlnAla: 3.643 ± 0.025	0.487GlnCys: 0.487 ± 0.008	2.201GlnAsp: 2.201 ± 0.018	2.519GlnGlu: 2.519 ± 0.019	1.324GlnPhe: 1.324 ± 0.014	2.539GlnGly: 2.539 ± 0.022	1.172GlnHis: 1.172 ± 0.015	1.995GlnIle: 1.995 ± 0.017	1.985GlnLys: 1.985 ± 0.019	3.513GlnLeu: 3.513 ± 0.023	0.934GlnMet: 0.934 ± 0.012	1.607GlnAsn: 1.607 ± 0.015	2.698GlnPro: 2.698 ± 0.026	2.46GlnGln: 2.46 ± 0.033	2.809GlnArg: 2.809 ± 0.023	3.34GlnSer: 3.34 ± 0.024	2.426GlnThr: 2.426 ± 0.02	2.236GlnVal: 2.236 ± 0.019	0.587GlnTrp: 0.587 ± 0.009	1.199GlnTyr: 1.199 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.935ArgAla: 4.935 ± 0.029	0.783ArgCys: 0.783 ± 0.012	3.544ArgAsp: 3.544 ± 0.027	3.927ArgGlu: 3.927 ± 0.031	2.107ArgPhe: 2.107 ± 0.017	3.755ArgGly: 3.755 ± 0.03	1.773ArgHis: 1.773 ± 0.016	2.905ArgIle: 2.905 ± 0.023	3.546ArgLys: 3.546 ± 0.028	5.795ArgLeu: 5.795 ± 0.032	1.332ArgMet: 1.332 ± 0.012	2.223ArgAsn: 2.223 ± 0.019	3.795ArgPro: 3.795 ± 0.026	2.833ArgGln: 2.833 ± 0.022	5.539ArgArg: 5.539 ± 0.041	4.972ArgSer: 4.972 ± 0.037	3.485ArgThr: 3.485 ± 0.025	3.318ArgVal: 3.318 ± 0.021	0.993ArgTrp: 0.993 ± 0.013	1.723ArgTyr: 1.723 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.659SerAla: 6.659 ± 0.034	0.909SerCys: 0.909 ± 0.013	4.103SerAsp: 4.103 ± 0.027	4.089SerGlu: 4.089 ± 0.031	2.967SerPhe: 2.967 ± 0.022	5.4SerGly: 5.4 ± 0.033	1.97SerHis: 1.97 ± 0.018	3.891SerIle: 3.891 ± 0.029	3.569SerLys: 3.569 ± 0.03	7.318SerLeu: 7.318 ± 0.037	1.735SerMet: 1.735 ± 0.017	2.852SerAsn: 2.852 ± 0.022	5.651SerPro: 5.651 ± 0.042	3.43SerGln: 3.43 ± 0.025	5.263SerArg: 5.263 ± 0.034	8.806SerSer: 8.806 ± 0.066	5.772SerThr: 5.772 ± 0.044	4.502SerVal: 4.502 ± 0.027	1.133SerTrp: 1.133 ± 0.013	2.004SerTyr: 2.004 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.336ThrAla: 5.336 ± 0.029	0.789ThrCys: 0.789 ± 0.011	2.839ThrAsp: 2.839 ± 0.022	3.057ThrGlu: 3.057 ± 0.023	2.277ThrPhe: 2.277 ± 0.019	4.046ThrGly: 4.046 ± 0.031	1.249ThrHis: 1.249 ± 0.014	3.042ThrIle: 3.042 ± 0.023	2.532ThrLys: 2.532 ± 0.023	5.256ThrLeu: 5.256 ± 0.033	1.249ThrMet: 1.249 ± 0.014	2.095ThrAsn: 2.095 ± 0.018	4.259ThrPro: 4.259 ± 0.029	2.144ThrGln: 2.144 ± 0.019	3.239ThrArg: 3.239 ± 0.024	5.572ThrSer: 5.572 ± 0.045	4.555ThrThr: 4.555 ± 0.051	3.74ThrVal: 3.74 ± 0.028	0.875ThrTrp: 0.875 ± 0.012	1.581ThrTyr: 1.581 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.326ValAla: 5.326 ± 0.028	0.848ValCys: 0.848 ± 0.011	3.789ValAsp: 3.789 ± 0.026	3.869ValGlu: 3.869 ± 0.028	2.455ValPhe: 2.455 ± 0.021	3.955ValGly: 3.955 ± 0.033	1.471ValHis: 1.471 ± 0.015	2.851ValIle: 2.851 ± 0.025	2.823ValLys: 2.823 ± 0.025	5.614ValLeu: 5.614 ± 0.034	1.318ValMet: 1.318 ± 0.014	2.203ValAsn: 2.203 ± 0.017	3.567ValPro: 3.567 ± 0.025	2.476ValGln: 2.476 ± 0.018	3.576ValArg: 3.576 ± 0.024	4.554ValSer: 4.554 ± 0.026	3.471ValThr: 3.471 ± 0.025	4.358ValVal: 4.358 ± 0.025	0.862ValTrp: 0.862 ± 0.011	1.679ValTyr: 1.679 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.161TrpAla: 1.161 ± 0.014	0.213TrpCys: 0.213 ± 0.005	0.864TrpAsp: 0.864 ± 0.012	0.817TrpGlu: 0.817 ± 0.011	0.553TrpPhe: 0.553 ± 0.01	0.875TrpGly: 0.875 ± 0.012	0.389TrpHis: 0.389 ± 0.008	0.8TrpIle: 0.8 ± 0.011	0.786TrpLys: 0.786 ± 0.011	1.424TrpLeu: 1.424 ± 0.017	0.367TrpMet: 0.367 ± 0.008	0.611TrpAsn: 0.611 ± 0.011	0.651TrpPro: 0.651 ± 0.011	0.611TrpGln: 0.611 ± 0.009	1.006TrpArg: 1.006 ± 0.013	1.1TrpSer: 1.1 ± 0.014	1.0TrpThr: 1.0 ± 0.012	0.868TrpVal: 0.868 ± 0.011	0.292TrpTrp: 0.292 ± 0.007	0.461TrpTyr: 0.461 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.174TyrAla: 2.174 ± 0.018	0.435TyrCys: 0.435 ± 0.007	1.633TyrAsp: 1.633 ± 0.016	1.487TyrGlu: 1.487 ± 0.015	1.214TyrPhe: 1.214 ± 0.014	2.06TyrGly: 2.06 ± 0.022	0.797TyrHis: 0.797 ± 0.012	1.314TyrIle: 1.314 ± 0.014	1.013TyrLys: 1.013 ± 0.013	2.719TyrLeu: 2.719 ± 0.022	0.592TyrMet: 0.592 ± 0.009	1.055TyrAsn: 1.055 ± 0.012	1.514TyrPro: 1.514 ± 0.017	1.126TyrGln: 1.126 ± 0.016	1.651TyrArg: 1.651 ± 0.015	1.997TyrSer: 1.997 ± 0.019	1.551TyrThr: 1.551 ± 0.016	1.603TyrVal: 1.603 ± 0.014	0.444TyrTrp: 0.444 ± 0.009	0.885TyrTyr: 0.885 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13606 proteins (6726764 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---