Amino acid dipepetide frequency for Luteovulum ovatum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.249AlaAla: 21.249 ± 0.277
1.221AlaCys: 1.221 ± 0.039
7.732AlaAsp: 7.732 ± 0.091
9.086AlaGlu: 9.086 ± 0.103
4.425AlaPhe: 4.425 ± 0.071
12.32AlaGly: 12.32 ± 0.221
2.51AlaHis: 2.51 ± 0.055
5.882AlaIle: 5.882 ± 0.081
3.252AlaLys: 3.252 ± 0.065
15.687AlaLeu: 15.687 ± 0.151
3.883AlaMet: 3.883 ± 0.068
2.558AlaAsn: 2.558 ± 0.058
7.062AlaPro: 7.062 ± 0.11
4.354AlaGln: 4.354 ± 0.076
11.066AlaArg: 11.066 ± 0.129
5.825AlaSer: 5.825 ± 0.108
6.656AlaThr: 6.656 ± 0.119
9.407AlaVal: 9.407 ± 0.132
1.469AlaTrp: 1.469 ± 0.035
2.268AlaTyr: 2.268 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
1.086CysAla: 1.086 ± 0.034
0.115CysCys: 0.115 ± 0.012
0.594CysAsp: 0.594 ± 0.025
0.434CysGlu: 0.434 ± 0.019
0.34CysPhe: 0.34 ± 0.017
0.98CysGly: 0.98 ± 0.031
0.268CysHis: 0.268 ± 0.015
0.382CysIle: 0.382 ± 0.017
0.17CysLys: 0.17 ± 0.013
0.9CysLeu: 0.9 ± 0.031
0.17CysMet: 0.17 ± 0.013
0.193CysAsn: 0.193 ± 0.013
0.605CysPro: 0.605 ± 0.029
0.204CysGln: 0.204 ± 0.012
0.691CysArg: 0.691 ± 0.026
0.379CysSer: 0.379 ± 0.02
0.446CysThr: 0.446 ± 0.022
0.555CysVal: 0.555 ± 0.028
0.137CysTrp: 0.137 ± 0.013
0.176CysTyr: 0.176 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
7.352AspAla: 7.352 ± 0.094
0.531AspCys: 0.531 ± 0.022
2.951AspAsp: 2.951 ± 0.06
3.472AspGlu: 3.472 ± 0.078
2.149AspPhe: 2.149 ± 0.045
5.415AspGly: 5.415 ± 0.089
1.308AspHis: 1.308 ± 0.038
2.528AspIle: 2.528 ± 0.048
1.227AspLys: 1.227 ± 0.036
7.127AspLeu: 7.127 ± 0.093
1.34AspMet: 1.34 ± 0.035
0.938AspAsn: 0.938 ± 0.034
4.17AspPro: 4.17 ± 0.076
1.73AspGln: 1.73 ± 0.04
5.228AspArg: 5.228 ± 0.08
1.993AspSer: 1.993 ± 0.05
2.644AspThr: 2.644 ± 0.071
3.57AspVal: 3.57 ± 0.066
1.285AspTrp: 1.285 ± 0.039
1.375AspTyr: 1.375 ± 0.037
0.0AspXaa: 0.0 ± 0.0
Glu
8.709GluAla: 8.709 ± 0.102
0.322GluCys: 0.322 ± 0.017
2.928GluAsp: 2.928 ± 0.067
2.619GluGlu: 2.619 ± 0.065
1.607GluPhe: 1.607 ± 0.038
4.942GluGly: 4.942 ± 0.079
0.911GluHis: 0.911 ± 0.033
3.391GluIle: 3.391 ± 0.06
1.716GluLys: 1.716 ± 0.052
4.603GluLeu: 4.603 ± 0.082
1.591GluMet: 1.591 ± 0.04
1.251GluAsn: 1.251 ± 0.033
2.733GluPro: 2.733 ± 0.062
1.684GluGln: 1.684 ± 0.047
4.373GluArg: 4.373 ± 0.082
2.126GluSer: 2.126 ± 0.041
3.538GluThr: 3.538 ± 0.059
4.531GluVal: 4.531 ± 0.076
0.725GluTrp: 0.725 ± 0.027
0.81GluTyr: 0.81 ± 0.026
0.0GluXaa: 0.0 ± 0.0
Phe
4.569PheAla: 4.569 ± 0.071
0.375PheCys: 0.375 ± 0.018
2.667PheAsp: 2.667 ± 0.05
1.88PheGlu: 1.88 ± 0.044
1.311PhePhe: 1.311 ± 0.042
3.605PheGly: 3.605 ± 0.065
0.754PheHis: 0.754 ± 0.025
1.379PheIle: 1.379 ± 0.038
0.745PheLys: 0.745 ± 0.022
3.507PheLeu: 3.507 ± 0.073
0.707PheMet: 0.707 ± 0.03
0.852PheAsn: 0.852 ± 0.027
1.534PhePro: 1.534 ± 0.04
0.976PheGln: 0.976 ± 0.028
2.566PheArg: 2.566 ± 0.049
1.869PheSer: 1.869 ± 0.042
1.998PheThr: 1.998 ± 0.044
2.44PheVal: 2.44 ± 0.05
0.513PheTrp: 0.513 ± 0.021
0.739PheTyr: 0.739 ± 0.026
0.0PheXaa: 0.0 ± 0.0
Gly
11.077GlyAla: 11.077 ± 0.18
0.921GlyCys: 0.921 ± 0.033
4.465GlyAsp: 4.465 ± 0.11
4.414GlyGlu: 4.414 ± 0.068
3.718GlyPhe: 3.718 ± 0.063
7.728GlyGly: 7.728 ± 0.189
1.969GlyHis: 1.969 ± 0.046
4.198GlyIle: 4.198 ± 0.059
2.658GlyLys: 2.658 ± 0.055
9.956GlyLeu: 9.956 ± 0.108
2.525GlyMet: 2.525 ± 0.048
1.988GlyAsn: 1.988 ± 0.084
4.2GlyPro: 4.2 ± 0.07
3.25GlyGln: 3.25 ± 0.056
7.25GlyArg: 7.25 ± 0.093
4.109GlySer: 4.109 ± 0.092
4.903GlyThr: 4.903 ± 0.121
6.21GlyVal: 6.21 ± 0.096
1.687GlyTrp: 1.687 ± 0.042
2.005GlyTyr: 2.005 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
2.461HisAla: 2.461 ± 0.041
0.22HisCys: 0.22 ± 0.014
1.289HisAsp: 1.289 ± 0.038
1.016HisGlu: 1.016 ± 0.033
0.779HisPhe: 0.779 ± 0.023
2.023HisGly: 2.023 ± 0.05
0.54HisHis: 0.54 ± 0.026
0.812HisIle: 0.812 ± 0.031
0.376HisLys: 0.376 ± 0.017
2.241HisLeu: 2.241 ± 0.053
0.458HisMet: 0.458 ± 0.021
0.353HisAsn: 0.353 ± 0.019
1.487HisPro: 1.487 ± 0.038
0.555HisGln: 0.555 ± 0.024
1.62HisArg: 1.62 ± 0.043
0.834HisSer: 0.834 ± 0.026
0.697HisThr: 0.697 ± 0.025
1.561HisVal: 1.561 ± 0.039
0.37HisTrp: 0.37 ± 0.021
0.493HisTyr: 0.493 ± 0.022
0.0HisXaa: 0.0 ± 0.0
Ile
6.743IleAla: 6.743 ± 0.088
0.564IleCys: 0.564 ± 0.022
3.304IleAsp: 3.304 ± 0.056
3.37IleGlu: 3.37 ± 0.056
1.571IlePhe: 1.571 ± 0.04
4.458IleGly: 4.458 ± 0.08
0.961IleHis: 0.961 ± 0.031
1.498IleIle: 1.498 ± 0.039
0.979IleLys: 0.979 ± 0.034
4.661IleLeu: 4.661 ± 0.077
0.798IleMet: 0.798 ± 0.027
1.026IleAsn: 1.026 ± 0.032
2.152IlePro: 2.152 ± 0.053
1.005IleGln: 1.005 ± 0.03
3.708IleArg: 3.708 ± 0.056
2.485IleSer: 2.485 ± 0.054
2.448IleThr: 2.448 ± 0.052
3.47IleVal: 3.47 ± 0.065
0.672IleTrp: 0.672 ± 0.027
0.909IleTyr: 0.909 ± 0.028
0.0IleXaa: 0.0 ± 0.0
Lys
3.587LysAla: 3.587 ± 0.065
0.158LysCys: 0.158 ± 0.011
1.367LysAsp: 1.367 ± 0.048
1.178LysGlu: 1.178 ± 0.042
0.689LysPhe: 0.689 ± 0.023
2.434LysGly: 2.434 ± 0.057
0.461LysHis: 0.461 ± 0.024
1.318LysIle: 1.318 ± 0.038
0.939LysLys: 0.939 ± 0.035
2.501LysLeu: 2.501 ± 0.06
0.672LysMet: 0.672 ± 0.028
0.588LysAsn: 0.588 ± 0.027
1.629LysPro: 1.629 ± 0.046
0.706LysGln: 0.706 ± 0.026
1.912LysArg: 1.912 ± 0.055
1.352LysSer: 1.352 ± 0.037
1.533LysThr: 1.533 ± 0.042
2.011LysVal: 2.011 ± 0.046
0.301LysTrp: 0.301 ± 0.017
0.443LysTyr: 0.443 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
15.739LeuAla: 15.739 ± 0.15
0.996LeuCys: 0.996 ± 0.035
6.436LeuAsp: 6.436 ± 0.079
4.704LeuGlu: 4.704 ± 0.068
3.431LeuPhe: 3.431 ± 0.074
8.937LeuGly: 8.937 ± 0.104
2.058LeuHis: 2.058 ± 0.048
4.821LeuIle: 4.821 ± 0.072
2.85LeuLys: 2.85 ± 0.064
9.627LeuLeu: 9.627 ± 0.132
2.628LeuMet: 2.628 ± 0.058
2.331LeuAsn: 2.331 ± 0.046
6.469LeuPro: 6.469 ± 0.091
2.601LeuGln: 2.601 ± 0.048
8.279LeuArg: 8.279 ± 0.104
6.174LeuSer: 6.174 ± 0.076
6.22LeuThr: 6.22 ± 0.098
7.611LeuVal: 7.611 ± 0.094
1.402LeuTrp: 1.402 ± 0.038
1.841LeuTyr: 1.841 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
3.637MetAla: 3.637 ± 0.06
0.141MetCys: 0.141 ± 0.011
1.236MetAsp: 1.236 ± 0.036
1.148MetGlu: 1.148 ± 0.035
0.645MetPhe: 0.645 ± 0.027
2.12MetGly: 2.12 ± 0.048
0.41MetHis: 0.41 ± 0.02
1.327MetIle: 1.327 ± 0.036
0.895MetLys: 0.895 ± 0.03
2.456MetLeu: 2.456 ± 0.052
0.664MetMet: 0.664 ± 0.026
0.709MetAsn: 0.709 ± 0.025
1.504MetPro: 1.504 ± 0.038
0.91MetGln: 0.91 ± 0.033
1.975MetArg: 1.975 ± 0.046
1.36MetSer: 1.36 ± 0.033
1.974MetThr: 1.974 ± 0.043
1.892MetVal: 1.892 ± 0.046
0.215MetTrp: 0.215 ± 0.014
0.269MetTyr: 0.269 ± 0.013
0.0MetXaa: 0.0 ± 0.0
Asn
2.682AsnAla: 2.682 ± 0.051
0.229AsnCys: 0.229 ± 0.015
1.238AsnAsp: 1.238 ± 0.069
0.949AsnGlu: 0.949 ± 0.032
0.776AsnPhe: 0.776 ± 0.027
2.021AsnGly: 2.021 ± 0.044
0.418AsnHis: 0.418 ± 0.019
1.059AsnIle: 1.059 ± 0.033
0.467AsnLys: 0.467 ± 0.019
2.197AsnLeu: 2.197 ± 0.046
0.517AsnMet: 0.517 ± 0.021
0.48AsnAsn: 0.48 ± 0.021
1.679AsnPro: 1.679 ± 0.038
0.514AsnGln: 0.514 ± 0.021
1.737AsnArg: 1.737 ± 0.04
0.874AsnSer: 0.874 ± 0.03
1.025AsnThr: 1.025 ± 0.033
1.467AsnVal: 1.467 ± 0.037
0.396AsnTrp: 0.396 ± 0.023
0.457AsnTyr: 0.457 ± 0.02
0.0AsnXaa: 0.0 ± 0.0
Pro
7.905ProAla: 7.905 ± 0.12
0.434ProCys: 0.434 ± 0.02
4.182ProAsp: 4.182 ± 0.072
4.276ProGlu: 4.276 ± 0.071
1.979ProPhe: 1.979 ± 0.045
5.322ProGly: 5.322 ± 0.076
1.1ProHis: 1.1 ± 0.036
2.107ProIle: 2.107 ± 0.042
1.482ProLys: 1.482 ± 0.043
5.191ProLeu: 5.191 ± 0.086
1.391ProMet: 1.391 ± 0.032
1.056ProAsn: 1.056 ± 0.034
3.101ProPro: 3.101 ± 0.079
1.731ProGln: 1.731 ± 0.042
3.512ProArg: 3.512 ± 0.068
2.493ProSer: 2.493 ± 0.051
2.512ProThr: 2.512 ± 0.053
4.823ProVal: 4.823 ± 0.071
0.75ProTrp: 0.75 ± 0.032
0.961ProTyr: 0.961 ± 0.03
0.0ProXaa: 0.0 ± 0.0
Gln
4.274GlnAla: 4.274 ± 0.063
0.183GlnCys: 0.183 ± 0.011
1.499GlnAsp: 1.499 ± 0.041
1.411GlnGlu: 1.411 ± 0.034
0.911GlnPhe: 0.911 ± 0.026
2.669GlnGly: 2.669 ± 0.045
0.541GlnHis: 0.541 ± 0.022
1.815GlnIle: 1.815 ± 0.039
0.903GlnLys: 0.903 ± 0.029
2.547GlnLeu: 2.547 ± 0.055
0.938GlnMet: 0.938 ± 0.034
0.673GlnAsn: 0.673 ± 0.028
1.9GlnPro: 1.9 ± 0.043
0.956GlnGln: 0.956 ± 0.034
2.24GlnArg: 2.24 ± 0.052
1.496GlnSer: 1.496 ± 0.04
1.771GlnThr: 1.771 ± 0.045
2.409GlnVal: 2.409 ± 0.045
0.359GlnTrp: 0.359 ± 0.017
0.434GlnTyr: 0.434 ± 0.018
0.0GlnXaa: 0.0 ± 0.0
Arg
10.052ArgAla: 10.052 ± 0.119
0.574ArgCys: 0.574 ± 0.023
4.45ArgAsp: 4.45 ± 0.068
4.014ArgGlu: 4.014 ± 0.071
2.994ArgPhe: 2.994 ± 0.059
5.437ArgGly: 5.437 ± 0.078
1.897ArgHis: 1.897 ± 0.044
4.503ArgIle: 4.503 ± 0.052
2.083ArgLys: 2.083 ± 0.055
9.573ArgLeu: 9.573 ± 0.104
2.274ArgMet: 2.274 ± 0.048
1.63ArgAsn: 1.63 ± 0.041
4.455ArgPro: 4.455 ± 0.085
2.534ArgGln: 2.534 ± 0.052
6.589ArgArg: 6.589 ± 0.116
3.377ArgSer: 3.377 ± 0.052
3.558ArgThr: 3.558 ± 0.057
5.237ArgVal: 5.237 ± 0.068
1.119ArgTrp: 1.119 ± 0.04
1.469ArgTyr: 1.469 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
5.978SerAla: 5.978 ± 0.116
0.403SerCys: 0.403 ± 0.021
2.905SerAsp: 2.905 ± 0.055
2.39SerGlu: 2.39 ± 0.047
1.994SerPhe: 1.994 ± 0.046
5.115SerGly: 5.115 ± 0.087
0.976SerHis: 0.976 ± 0.031
2.022SerIle: 2.022 ± 0.046
1.072SerLys: 1.072 ± 0.031
4.83SerLeu: 4.83 ± 0.075
1.099SerMet: 1.099 ± 0.033
0.999SerAsn: 0.999 ± 0.032
2.544SerPro: 2.544 ± 0.057
1.377SerGln: 1.377 ± 0.035
3.553SerArg: 3.553 ± 0.059
2.18SerSer: 2.18 ± 0.057
2.221SerThr: 2.221 ± 0.048
3.658SerVal: 3.658 ± 0.09
0.634SerTrp: 0.634 ± 0.023
1.065SerTyr: 1.065 ± 0.03
0.0SerXaa: 0.0 ± 0.0
Thr
6.939ThrAla: 6.939 ± 0.136
0.481ThrCys: 0.481 ± 0.021
3.155ThrAsp: 3.155 ± 0.064
2.889ThrGlu: 2.889 ± 0.044
1.938ThrPhe: 1.938 ± 0.04
5.52ThrGly: 5.52 ± 0.136
1.03ThrHis: 1.03 ± 0.029
2.532ThrIle: 2.532 ± 0.07
1.135ThrLys: 1.135 ± 0.033
6.052ThrLeu: 6.052 ± 0.094
1.116ThrMet: 1.116 ± 0.033
1.067ThrAsn: 1.067 ± 0.032
3.496ThrPro: 3.496 ± 0.062
1.352ThrGln: 1.352 ± 0.039
3.711ThrArg: 3.711 ± 0.053
2.427ThrSer: 2.427 ± 0.058
2.881ThrThr: 2.881 ± 0.067
4.357ThrVal: 4.357 ± 0.098
0.63ThrTrp: 0.63 ± 0.024
1.019ThrTyr: 1.019 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
10.123ValAla: 10.123 ± 0.125
0.624ValCys: 0.624 ± 0.022
3.819ValAsp: 3.819 ± 0.056
4.285ValGlu: 4.285 ± 0.072
2.499ValPhe: 2.499 ± 0.051
5.363ValGly: 5.363 ± 0.094
1.302ValHis: 1.302 ± 0.037
3.821ValIle: 3.821 ± 0.066
1.995ValLys: 1.995 ± 0.049
7.735ValLeu: 7.735 ± 0.088
1.93ValMet: 1.93 ± 0.043
1.708ValAsn: 1.708 ± 0.043
3.885ValPro: 3.885 ± 0.068
2.202ValGln: 2.202 ± 0.043
4.891ValArg: 4.891 ± 0.064
3.964ValSer: 3.964 ± 0.08
5.051ValThr: 5.051 ± 0.124
5.926ValVal: 5.926 ± 0.094
1.016ValTrp: 1.016 ± 0.03
1.238ValTyr: 1.238 ± 0.037
0.0ValXaa: 0.0 ± 0.0
Trp
1.514TrpAla: 1.514 ± 0.04
0.139TrpCys: 0.139 ± 0.01
0.756TrpAsp: 0.756 ± 0.028
0.582TrpGlu: 0.582 ± 0.025
0.534TrpPhe: 0.534 ± 0.021
1.011TrpGly: 1.011 ± 0.035
0.323TrpHis: 0.323 ± 0.018
0.663TrpIle: 0.663 ± 0.024
0.411TrpLys: 0.411 ± 0.021
1.811TrpLeu: 1.811 ± 0.048
0.371TrpMet: 0.371 ± 0.018
0.336TrpAsn: 0.336 ± 0.016
0.787TrpPro: 0.787 ± 0.031
0.689TrpGln: 0.689 ± 0.026
1.322TrpArg: 1.322 ± 0.042
0.763TrpSer: 0.763 ± 0.03
0.765TrpThr: 0.765 ± 0.026
0.941TrpVal: 0.941 ± 0.03
0.223TrpTrp: 0.223 ± 0.015
0.246TrpTyr: 0.246 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.232TyrAla: 2.232 ± 0.044
0.196TyrCys: 0.196 ± 0.014
1.361TyrAsp: 1.361 ± 0.035
0.996TyrGlu: 0.996 ± 0.034
0.697TyrPhe: 0.697 ± 0.025
1.809TyrGly: 1.809 ± 0.043
0.446TyrHis: 0.446 ± 0.022
0.723TyrIle: 0.723 ± 0.028
0.426TyrLys: 0.426 ± 0.021
1.95TyrLeu: 1.95 ± 0.043
0.414TyrMet: 0.414 ± 0.02
0.443TyrAsn: 0.443 ± 0.02
0.918TyrPro: 0.918 ± 0.03
0.6TyrGln: 0.6 ± 0.021
1.6TyrArg: 1.6 ± 0.039
0.937TyrSer: 0.937 ± 0.031
0.886TyrThr: 0.886 ± 0.029
1.302TyrVal: 1.302 ± 0.032
0.282TyrTrp: 0.282 ± 0.018
0.452TyrTyr: 0.452 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3594 proteins (1137852 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski