Amino acid dipepetide frequency for Sulfolobus islandicus rudivirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
1.939AlaAsp: 1.939 ± 0.57
1.711AlaGlu: 1.711 ± 0.544
3.08AlaPhe: 3.08 ± 0.536
1.939AlaGly: 1.939 ± 0.582
0.0AlaHis: 0.0 ± 0.0
5.704AlaIle: 5.704 ± 0.686
4.449AlaLys: 4.449 ± 0.665
4.107AlaLeu: 4.107 ± 0.801
0.456AlaMet: 0.456 ± 0.231
3.536AlaAsn: 3.536 ± 0.57
0.913AlaPro: 0.913 ± 0.325
2.167AlaGln: 2.167 ± 0.635
1.939AlaArg: 1.939 ± 0.451
1.483AlaSer: 1.483 ± 0.441
1.711AlaThr: 1.711 ± 0.502
2.282AlaVal: 2.282 ± 0.592
0.913AlaTrp: 0.913 ± 0.347
2.852AlaTyr: 2.852 ± 0.402
0.0AlaXaa: 0.0 ± 0.0
Cys
0.228CysAla: 0.228 ± 0.158
0.114CysCys: 0.114 ± 0.109
0.684CysAsp: 0.684 ± 0.256
0.57CysGlu: 0.57 ± 0.297
0.114CysPhe: 0.114 ± 0.105
0.57CysGly: 0.57 ± 0.26
0.0CysHis: 0.0 ± 0.0
0.799CysIle: 0.799 ± 0.313
0.799CysLys: 0.799 ± 0.381
0.342CysLeu: 0.342 ± 0.234
0.228CysMet: 0.228 ± 0.205
0.57CysAsn: 0.57 ± 0.227
0.114CysPro: 0.114 ± 0.14
0.456CysGln: 0.456 ± 0.206
0.57CysArg: 0.57 ± 0.271
0.456CysSer: 0.456 ± 0.189
0.114CysThr: 0.114 ± 0.115
0.114CysVal: 0.114 ± 0.101
0.114CysTrp: 0.114 ± 0.12
0.57CysTyr: 0.57 ± 0.255
0.0CysXaa: 0.0 ± 0.0
Asp
1.027AspAla: 1.027 ± 0.323
0.57AspCys: 0.57 ± 0.267
1.825AspAsp: 1.825 ± 0.547
3.422AspGlu: 3.422 ± 0.728
3.194AspPhe: 3.194 ± 0.65
1.369AspGly: 1.369 ± 0.419
0.456AspHis: 0.456 ± 0.26
5.019AspIle: 5.019 ± 0.889
3.308AspLys: 3.308 ± 0.663
7.301AspLeu: 7.301 ± 0.719
0.913AspMet: 0.913 ± 0.364
3.08AspAsn: 3.08 ± 0.482
1.027AspPro: 1.027 ± 0.353
1.141AspGln: 1.141 ± 0.372
1.255AspArg: 1.255 ± 0.353
3.08AspSer: 3.08 ± 0.525
2.053AspThr: 2.053 ± 0.38
1.939AspVal: 1.939 ± 0.508
0.228AspTrp: 0.228 ± 0.167
2.624AspTyr: 2.624 ± 0.546
0.0AspXaa: 0.0 ± 0.0
Glu
0.799GluAla: 0.799 ± 0.238
0.228GluCys: 0.228 ± 0.206
3.08GluAsp: 3.08 ± 0.739
6.16GluGlu: 6.16 ± 1.201
4.335GluPhe: 4.335 ± 0.949
1.255GluGly: 1.255 ± 0.289
0.342GluHis: 0.342 ± 0.203
10.267GluIle: 10.267 ± 1.687
7.643GluLys: 7.643 ± 1.557
7.529GluLeu: 7.529 ± 1.399
1.027GluMet: 1.027 ± 0.42
4.563GluAsn: 4.563 ± 0.763
1.141GluPro: 1.141 ± 0.304
2.852GluGln: 2.852 ± 0.665
1.711GluArg: 1.711 ± 0.467
2.738GluSer: 2.738 ± 0.59
2.624GluThr: 2.624 ± 0.438
4.677GluVal: 4.677 ± 0.842
0.57GluTrp: 0.57 ± 0.286
4.677GluTyr: 4.677 ± 1.157
0.0GluXaa: 0.0 ± 0.0
Phe
2.966PheAla: 2.966 ± 0.757
1.255PheCys: 1.255 ± 0.483
3.08PheAsp: 3.08 ± 0.413
6.16PheGlu: 6.16 ± 1.336
3.08PhePhe: 3.08 ± 0.61
2.738PheGly: 2.738 ± 0.553
0.913PheHis: 0.913 ± 0.398
5.59PheIle: 5.59 ± 0.874
5.248PheLys: 5.248 ± 0.888
5.248PheLeu: 5.248 ± 0.919
0.684PheMet: 0.684 ± 0.181
3.08PheAsn: 3.08 ± 0.667
1.369PhePro: 1.369 ± 0.424
2.396PheGln: 2.396 ± 0.384
1.825PheArg: 1.825 ± 0.412
3.993PheSer: 3.993 ± 0.837
3.308PheThr: 3.308 ± 0.704
3.194PheVal: 3.194 ± 0.551
0.799PheTrp: 0.799 ± 0.278
3.308PheTyr: 3.308 ± 0.53
0.0PheXaa: 0.0 ± 0.0
Gly
1.597GlyAla: 1.597 ± 0.342
0.228GlyCys: 0.228 ± 0.167
1.369GlyAsp: 1.369 ± 0.339
2.396GlyGlu: 2.396 ± 0.466
2.738GlyPhe: 2.738 ± 0.432
2.396GlyGly: 2.396 ± 0.575
0.228GlyHis: 0.228 ± 0.158
4.791GlyIle: 4.791 ± 0.897
2.966GlyLys: 2.966 ± 0.552
3.422GlyLeu: 3.422 ± 0.454
1.369GlyMet: 1.369 ± 0.306
3.65GlyAsn: 3.65 ± 0.939
0.342GlyPro: 0.342 ± 0.274
1.483GlyGln: 1.483 ± 0.427
0.684GlyArg: 0.684 ± 0.295
2.738GlySer: 2.738 ± 0.728
2.852GlyThr: 2.852 ± 0.616
1.825GlyVal: 1.825 ± 0.458
0.342GlyTrp: 0.342 ± 0.178
2.852GlyTyr: 2.852 ± 0.715
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.57HisAsp: 0.57 ± 0.233
0.913HisGlu: 0.913 ± 0.3
0.684HisPhe: 0.684 ± 0.347
0.342HisGly: 0.342 ± 0.243
0.114HisHis: 0.114 ± 0.119
1.141HisIle: 1.141 ± 0.345
0.684HisLys: 0.684 ± 0.328
1.825HisLeu: 1.825 ± 0.458
0.342HisMet: 0.342 ± 0.209
0.57HisAsn: 0.57 ± 0.26
0.228HisPro: 0.228 ± 0.173
0.114HisGln: 0.114 ± 0.122
0.114HisArg: 0.114 ± 0.121
0.684HisSer: 0.684 ± 0.272
0.342HisThr: 0.342 ± 0.174
0.799HisVal: 0.799 ± 0.313
0.0HisTrp: 0.0 ± 0.0
1.027HisTyr: 1.027 ± 0.316
0.0HisXaa: 0.0 ± 0.0
Ile
7.529IleAla: 7.529 ± 0.824
1.255IleCys: 1.255 ± 0.463
4.221IleAsp: 4.221 ± 0.971
7.985IleGlu: 7.985 ± 0.817
6.388IlePhe: 6.388 ± 0.938
3.765IleGly: 3.765 ± 0.589
1.711IleHis: 1.711 ± 0.552
9.24IleIle: 9.24 ± 1.146
9.354IleLys: 9.354 ± 1.399
7.985IleLeu: 7.985 ± 1.237
0.684IleMet: 0.684 ± 0.35
8.328IleAsn: 8.328 ± 0.876
5.133IlePro: 5.133 ± 0.827
3.765IleGln: 3.765 ± 0.825
2.738IleArg: 2.738 ± 0.604
8.556IleSer: 8.556 ± 0.859
5.362IleThr: 5.362 ± 0.888
6.845IleVal: 6.845 ± 1.078
0.799IleTrp: 0.799 ± 0.209
5.476IleTyr: 5.476 ± 0.723
0.0IleXaa: 0.0 ± 0.0
Lys
2.51LysAla: 2.51 ± 0.629
0.456LysCys: 0.456 ± 0.206
4.677LysAsp: 4.677 ± 0.814
6.502LysGlu: 6.502 ± 1.072
5.019LysPhe: 5.019 ± 0.975
1.711LysGly: 1.711 ± 0.447
1.255LysHis: 1.255 ± 0.431
10.609LysIle: 10.609 ± 1.182
7.187LysLys: 7.187 ± 1.164
7.985LysLeu: 7.985 ± 1.027
2.852LysMet: 2.852 ± 0.597
4.905LysAsn: 4.905 ± 0.896
1.255LysPro: 1.255 ± 0.32
3.993LysGln: 3.993 ± 0.673
3.308LysArg: 3.308 ± 0.741
4.791LysSer: 4.791 ± 0.673
3.536LysThr: 3.536 ± 0.604
4.677LysVal: 4.677 ± 1.023
0.342LysTrp: 0.342 ± 0.192
4.791LysTyr: 4.791 ± 0.911
0.0LysXaa: 0.0 ± 0.0
Leu
3.993LeuAla: 3.993 ± 0.573
0.57LeuCys: 0.57 ± 0.327
4.905LeuAsp: 4.905 ± 0.625
5.932LeuGlu: 5.932 ± 1.095
4.335LeuPhe: 4.335 ± 0.868
3.879LeuGly: 3.879 ± 0.943
1.027LeuHis: 1.027 ± 0.403
8.784LeuIle: 8.784 ± 1.16
7.985LeuLys: 7.985 ± 1.186
10.039LeuLeu: 10.039 ± 1.402
1.483LeuMet: 1.483 ± 0.479
6.959LeuAsn: 6.959 ± 1.074
3.08LeuPro: 3.08 ± 0.486
6.502LeuGln: 6.502 ± 1.183
3.08LeuArg: 3.08 ± 0.67
7.871LeuSer: 7.871 ± 1.061
5.59LeuThr: 5.59 ± 0.803
4.563LeuVal: 4.563 ± 0.751
0.57LeuTrp: 0.57 ± 0.241
6.845LeuTyr: 6.845 ± 1.103
0.0LeuXaa: 0.0 ± 0.0
Met
0.57MetAla: 0.57 ± 0.28
0.228MetCys: 0.228 ± 0.168
0.913MetAsp: 0.913 ± 0.344
1.255MetGlu: 1.255 ± 0.438
0.913MetPhe: 0.913 ± 0.274
0.57MetGly: 0.57 ± 0.22
0.342MetHis: 0.342 ± 0.21
1.255MetIle: 1.255 ± 0.365
2.053MetLys: 2.053 ± 0.594
0.913MetLeu: 0.913 ± 0.356
0.114MetMet: 0.114 ± 0.111
2.053MetAsn: 2.053 ± 0.443
1.141MetPro: 1.141 ± 0.465
0.342MetGln: 0.342 ± 0.187
0.684MetArg: 0.684 ± 0.281
2.282MetSer: 2.282 ± 0.529
0.684MetThr: 0.684 ± 0.262
0.57MetVal: 0.57 ± 0.256
0.456MetTrp: 0.456 ± 0.237
0.913MetTyr: 0.913 ± 0.347
0.0MetXaa: 0.0 ± 0.0
Asn
4.221AsnAla: 4.221 ± 0.597
0.456AsnCys: 0.456 ± 0.222
2.852AsnAsp: 2.852 ± 0.665
4.677AsnGlu: 4.677 ± 0.793
4.791AsnPhe: 4.791 ± 0.677
4.221AsnGly: 4.221 ± 1.146
0.114AsnHis: 0.114 ± 0.104
6.959AsnIle: 6.959 ± 0.885
4.449AsnLys: 4.449 ± 0.628
7.643AsnLeu: 7.643 ± 1.051
1.939AsnMet: 1.939 ± 0.644
4.107AsnAsn: 4.107 ± 1.038
2.852AsnPro: 2.852 ± 0.581
3.08AsnGln: 3.08 ± 0.819
1.939AsnArg: 1.939 ± 0.525
5.59AsnSer: 5.59 ± 1.008
3.879AsnThr: 3.879 ± 0.884
4.221AsnVal: 4.221 ± 0.707
0.684AsnTrp: 0.684 ± 0.3
4.221AsnTyr: 4.221 ± 0.961
0.0AsnXaa: 0.0 ± 0.0
Pro
1.141ProAla: 1.141 ± 0.367
0.342ProCys: 0.342 ± 0.229
2.167ProAsp: 2.167 ± 0.407
1.027ProGlu: 1.027 ± 0.301
1.939ProPhe: 1.939 ± 0.408
1.255ProGly: 1.255 ± 0.569
0.342ProHis: 0.342 ± 0.181
2.966ProIle: 2.966 ± 0.608
1.597ProLys: 1.597 ± 0.338
3.194ProLeu: 3.194 ± 0.765
0.0ProMet: 0.0 ± 0.0
3.08ProAsn: 3.08 ± 0.616
1.825ProPro: 1.825 ± 0.352
2.053ProGln: 2.053 ± 0.47
0.799ProArg: 0.799 ± 0.307
1.597ProSer: 1.597 ± 0.343
1.939ProThr: 1.939 ± 0.491
2.053ProVal: 2.053 ± 0.497
0.342ProTrp: 0.342 ± 0.192
1.825ProTyr: 1.825 ± 0.501
0.0ProXaa: 0.0 ± 0.0
Gln
1.369GlnAla: 1.369 ± 0.346
0.342GlnCys: 0.342 ± 0.257
1.825GlnAsp: 1.825 ± 0.414
2.738GlnGlu: 2.738 ± 0.583
3.422GlnPhe: 3.422 ± 0.633
1.141GlnGly: 1.141 ± 0.291
0.342GlnHis: 0.342 ± 0.174
5.476GlnIle: 5.476 ± 0.994
3.308GlnLys: 3.308 ± 0.88
6.502GlnLeu: 6.502 ± 1.254
0.456GlnMet: 0.456 ± 0.216
4.335GlnAsn: 4.335 ± 0.709
1.255GlnPro: 1.255 ± 0.345
2.51GlnGln: 2.51 ± 0.525
1.027GlnArg: 1.027 ± 0.296
1.939GlnSer: 1.939 ± 0.444
2.624GlnThr: 2.624 ± 0.442
2.053GlnVal: 2.053 ± 0.451
0.228GlnTrp: 0.228 ± 0.145
3.422GlnTyr: 3.422 ± 0.551
0.0GlnXaa: 0.0 ± 0.0
Arg
0.456ArgAla: 0.456 ± 0.271
0.114ArgCys: 0.114 ± 0.101
1.141ArgAsp: 1.141 ± 0.386
2.624ArgGlu: 2.624 ± 0.663
1.141ArgPhe: 1.141 ± 0.347
1.027ArgGly: 1.027 ± 0.494
0.342ArgHis: 0.342 ± 0.202
3.308ArgIle: 3.308 ± 0.64
4.107ArgLys: 4.107 ± 0.838
2.053ArgLeu: 2.053 ± 0.484
0.799ArgMet: 0.799 ± 0.27
2.624ArgAsn: 2.624 ± 0.449
0.684ArgPro: 0.684 ± 0.24
1.597ArgGln: 1.597 ± 0.539
1.027ArgArg: 1.027 ± 0.311
1.711ArgSer: 1.711 ± 0.449
2.053ArgThr: 2.053 ± 0.367
1.027ArgVal: 1.027 ± 0.309
0.342ArgTrp: 0.342 ± 0.192
2.396ArgTyr: 2.396 ± 0.494
0.0ArgXaa: 0.0 ± 0.0
Ser
3.308SerAla: 3.308 ± 0.663
0.57SerCys: 0.57 ± 0.239
2.966SerAsp: 2.966 ± 0.672
3.65SerGlu: 3.65 ± 0.757
4.335SerPhe: 4.335 ± 0.774
2.966SerGly: 2.966 ± 0.607
0.57SerHis: 0.57 ± 0.266
6.731SerIle: 6.731 ± 0.952
3.422SerLys: 3.422 ± 0.483
5.818SerLeu: 5.818 ± 0.7
1.939SerMet: 1.939 ± 0.527
5.704SerAsn: 5.704 ± 1.012
1.825SerPro: 1.825 ± 0.358
3.422SerGln: 3.422 ± 0.773
2.167SerArg: 2.167 ± 0.409
5.133SerSer: 5.133 ± 1.349
3.879SerThr: 3.879 ± 0.817
2.966SerVal: 2.966 ± 0.672
0.456SerTrp: 0.456 ± 0.175
3.536SerTyr: 3.536 ± 0.755
0.0SerXaa: 0.0 ± 0.0
Thr
2.396ThrAla: 2.396 ± 0.59
0.228ThrCys: 0.228 ± 0.165
1.939ThrAsp: 1.939 ± 0.531
2.624ThrGlu: 2.624 ± 0.52
3.536ThrPhe: 3.536 ± 0.549
3.536ThrGly: 3.536 ± 0.762
0.456ThrHis: 0.456 ± 0.267
6.845ThrIle: 6.845 ± 0.906
3.65ThrLys: 3.65 ± 0.773
4.335ThrLeu: 4.335 ± 0.726
0.799ThrMet: 0.799 ± 0.268
3.765ThrAsn: 3.765 ± 0.775
2.053ThrPro: 2.053 ± 0.367
1.825ThrGln: 1.825 ± 0.439
0.913ThrArg: 0.913 ± 0.311
3.422ThrSer: 3.422 ± 0.63
2.852ThrThr: 2.852 ± 0.731
3.08ThrVal: 3.08 ± 0.571
0.684ThrTrp: 0.684 ± 0.273
2.396ThrTyr: 2.396 ± 0.448
0.0ThrXaa: 0.0 ± 0.0
Val
2.396ValAla: 2.396 ± 0.534
0.114ValCys: 0.114 ± 0.117
2.282ValAsp: 2.282 ± 0.482
3.879ValGlu: 3.879 ± 0.642
3.194ValPhe: 3.194 ± 0.51
2.51ValGly: 2.51 ± 0.486
0.684ValHis: 0.684 ± 0.25
4.905ValIle: 4.905 ± 0.612
5.932ValLys: 5.932 ± 0.977
5.019ValLeu: 5.019 ± 0.925
0.684ValMet: 0.684 ± 0.284
3.422ValAsn: 3.422 ± 0.579
2.053ValPro: 2.053 ± 0.457
2.51ValGln: 2.51 ± 0.586
2.51ValArg: 2.51 ± 0.69
3.65ValSer: 3.65 ± 0.617
1.939ValThr: 1.939 ± 0.488
2.053ValVal: 2.053 ± 0.593
0.0ValTrp: 0.0 ± 0.0
3.536ValTyr: 3.536 ± 0.741
0.0ValXaa: 0.0 ± 0.0
Trp
0.228TrpAla: 0.228 ± 0.152
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.342TrpGlu: 0.342 ± 0.19
0.684TrpPhe: 0.684 ± 0.219
0.114TrpGly: 0.114 ± 0.113
0.114TrpHis: 0.114 ± 0.119
0.799TrpIle: 0.799 ± 0.277
0.684TrpLys: 0.684 ± 0.276
0.684TrpLeu: 0.684 ± 0.265
0.456TrpMet: 0.456 ± 0.226
0.913TrpAsn: 0.913 ± 0.303
0.0TrpPro: 0.0 ± 0.0
0.456TrpGln: 0.456 ± 0.187
1.141TrpArg: 1.141 ± 0.399
0.456TrpSer: 0.456 ± 0.295
0.342TrpThr: 0.342 ± 0.178
0.684TrpVal: 0.684 ± 0.267
0.228TrpTrp: 0.228 ± 0.151
0.342TrpTyr: 0.342 ± 0.174
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.449TyrAla: 4.449 ± 0.641
0.456TyrCys: 0.456 ± 0.233
2.396TyrAsp: 2.396 ± 0.53
3.65TyrGlu: 3.65 ± 0.672
3.308TyrPhe: 3.308 ± 0.537
2.966TyrGly: 2.966 ± 0.447
1.141TyrHis: 1.141 ± 0.44
5.932TyrIle: 5.932 ± 0.734
3.65TyrLys: 3.65 ± 0.648
6.046TyrLeu: 6.046 ± 0.806
0.913TyrMet: 0.913 ± 0.226
3.65TyrAsn: 3.65 ± 0.553
3.194TyrPro: 3.194 ± 0.549
3.65TyrGln: 3.65 ± 0.603
1.141TyrArg: 1.141 ± 0.409
3.194TyrSer: 3.194 ± 0.588
3.65TyrThr: 3.65 ± 0.95
3.65TyrVal: 3.65 ± 0.608
0.57TyrTrp: 0.57 ± 0.214
3.993TyrTyr: 3.993 ± 0.674
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 45 proteins (8767 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski