Amino acid dipepetide frequency for Cladophialophora psammophila CBS 110553

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.977AlaAla: 8.977 ± 0.058	1.118AlaCys: 1.118 ± 0.015	4.23AlaAsp: 4.23 ± 0.028	5.17AlaGlu: 5.17 ± 0.032	3.284AlaPhe: 3.284 ± 0.026	5.946AlaGly: 5.946 ± 0.039	1.811AlaHis: 1.811 ± 0.018	4.495AlaIle: 4.495 ± 0.035	4.068AlaLys: 4.068 ± 0.028	7.94AlaLeu: 7.94 ± 0.046	2.002AlaMet: 2.002 ± 0.02	2.974AlaAsn: 2.974 ± 0.024	4.388AlaPro: 4.388 ± 0.028	3.518AlaGln: 3.518 ± 0.031	5.063AlaArg: 5.063 ± 0.027	7.026AlaSer: 7.026 ± 0.042	5.326AlaThr: 5.326 ± 0.033	5.499AlaVal: 5.499 ± 0.032	1.211AlaTrp: 1.211 ± 0.014	2.238AlaTyr: 2.238 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.024CysAla: 1.024 ± 0.015	0.244CysCys: 0.244 ± 0.007	0.679CysAsp: 0.679 ± 0.012	0.608CysGlu: 0.608 ± 0.011	0.58CysPhe: 0.58 ± 0.01	0.937CysGly: 0.937 ± 0.014	0.343CysHis: 0.343 ± 0.007	0.753CysIle: 0.753 ± 0.011	0.51CysLys: 0.51 ± 0.009	1.348CysLeu: 1.348 ± 0.016	0.276CysMet: 0.276 ± 0.007	0.417CysAsn: 0.417 ± 0.008	0.678CysPro: 0.678 ± 0.012	0.473CysGln: 0.473 ± 0.009	0.784CysArg: 0.784 ± 0.011	0.908CysSer: 0.908 ± 0.014	0.692CysThr: 0.692 ± 0.012	0.834CysVal: 0.834 ± 0.013	0.219CysTrp: 0.219 ± 0.006	0.386CysTyr: 0.386 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.573AspAla: 4.573 ± 0.031	0.637AspCys: 0.637 ± 0.01	3.95AspAsp: 3.95 ± 0.038	4.34AspGlu: 4.34 ± 0.036	2.308AspPhe: 2.308 ± 0.02	3.969AspGly: 3.969 ± 0.028	1.289AspHis: 1.289 ± 0.011	3.026AspIle: 3.026 ± 0.021	2.353AspLys: 2.353 ± 0.022	5.225AspLeu: 5.225 ± 0.037	1.245AspMet: 1.245 ± 0.013	1.827AspAsn: 1.827 ± 0.018	3.363AspPro: 3.363 ± 0.025	2.011AspGln: 2.011 ± 0.02	3.101AspArg: 3.101 ± 0.025	3.794AspSer: 3.794 ± 0.026	2.877AspThr: 2.877 ± 0.021	3.723AspVal: 3.723 ± 0.031	0.906AspTrp: 0.906 ± 0.012	1.554AspTyr: 1.554 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.348GluAla: 5.348 ± 0.037	0.636GluCys: 0.636 ± 0.01	4.114GluAsp: 4.114 ± 0.036	5.21GluGlu: 5.21 ± 0.044	1.944GluPhe: 1.944 ± 0.019	3.743GluGly: 3.743 ± 0.026	1.437GluHis: 1.437 ± 0.016	3.216GluIle: 3.216 ± 0.023	3.651GluLys: 3.651 ± 0.03	5.165GluLeu: 5.165 ± 0.036	1.523GluMet: 1.523 ± 0.013	2.245GluAsn: 2.245 ± 0.02	2.677GluPro: 2.677 ± 0.024	2.518GluGln: 2.518 ± 0.023	3.934GluArg: 3.934 ± 0.03	4.102GluSer: 4.102 ± 0.03	3.412GluThr: 3.412 ± 0.026	3.624GluVal: 3.624 ± 0.026	0.891GluTrp: 0.891 ± 0.012	1.656GluTyr: 1.656 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.221PheAla: 3.221 ± 0.025	0.61PheCys: 0.61 ± 0.011	2.375PheAsp: 2.375 ± 0.023	2.24PheGlu: 2.24 ± 0.021	1.702PhePhe: 1.702 ± 0.019	2.987PheGly: 2.987 ± 0.028	0.93PheHis: 0.93 ± 0.012	1.837PheIle: 1.837 ± 0.021	1.476PheLys: 1.476 ± 0.016	3.646PheLeu: 3.646 ± 0.026	0.81PheMet: 0.81 ± 0.013	1.416PheAsn: 1.416 ± 0.017	1.99PhePro: 1.99 ± 0.019	1.458PheGln: 1.458 ± 0.017	2.018PheArg: 2.018 ± 0.019	2.948PheSer: 2.948 ± 0.025	2.13PheThr: 2.13 ± 0.019	2.529PheVal: 2.529 ± 0.022	0.7PheTrp: 0.7 ± 0.012	1.163PheTyr: 1.163 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.383GlyAla: 5.383 ± 0.029	0.895GlyCys: 0.895 ± 0.013	3.525GlyAsp: 3.525 ± 0.025	3.627GlyGlu: 3.627 ± 0.03	2.951GlyPhe: 2.951 ± 0.027	5.73GlyGly: 5.73 ± 0.048	1.74GlyHis: 1.74 ± 0.02	3.674GlyIle: 3.674 ± 0.026	3.458GlyLys: 3.458 ± 0.029	6.295GlyLeu: 6.295 ± 0.03	1.694GlyMet: 1.694 ± 0.019	2.461GlyAsn: 2.461 ± 0.021	3.435GlyPro: 3.435 ± 0.028	2.63GlyGln: 2.63 ± 0.023	4.191GlyArg: 4.191 ± 0.031	5.425GlySer: 5.425 ± 0.032	4.033GlyThr: 4.033 ± 0.03	4.47GlyVal: 4.47 ± 0.028	1.188GlyTrp: 1.188 ± 0.015	2.161GlyTyr: 2.161 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.935HisAla: 1.935 ± 0.02	0.335HisCys: 0.335 ± 0.008	1.344HisAsp: 1.344 ± 0.016	1.383HisGlu: 1.383 ± 0.015	0.979HisPhe: 0.979 ± 0.013	1.804HisGly: 1.804 ± 0.019	0.866HisHis: 0.866 ± 0.015	1.25HisIle: 1.25 ± 0.016	0.959HisLys: 0.959 ± 0.011	2.334HisLeu: 2.334 ± 0.023	0.495HisMet: 0.495 ± 0.009	0.825HisAsn: 0.825 ± 0.012	1.707HisPro: 1.707 ± 0.017	0.994HisGln: 0.994 ± 0.014	1.56HisArg: 1.56 ± 0.018	1.828HisSer: 1.828 ± 0.019	1.244HisThr: 1.244 ± 0.014	1.503HisVal: 1.503 ± 0.016	0.377HisTrp: 0.377 ± 0.007	0.709HisTyr: 0.709 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.404IleAla: 4.404 ± 0.032	0.833IleCys: 0.833 ± 0.012	2.894IleAsp: 2.894 ± 0.021	2.888IleGlu: 2.888 ± 0.023	2.101IlePhe: 2.101 ± 0.019	3.395IleGly: 3.395 ± 0.029	1.244IleHis: 1.244 ± 0.015	2.592IleIle: 2.592 ± 0.024	2.176IleLys: 2.176 ± 0.024	4.765IleLeu: 4.765 ± 0.029	1.024IleMet: 1.024 ± 0.013	1.817IleAsn: 1.817 ± 0.018	3.111IlePro: 3.111 ± 0.024	1.977IleGln: 1.977 ± 0.02	2.806IleArg: 2.806 ± 0.021	3.9IleSer: 3.9 ± 0.03	2.777IleThr: 2.777 ± 0.025	3.339IleVal: 3.339 ± 0.03	0.777IleTrp: 0.777 ± 0.011	1.525IleTyr: 1.525 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.172LysAla: 4.172 ± 0.029	0.514LysCys: 0.514 ± 0.01	2.788LysAsp: 2.788 ± 0.021	3.314LysGlu: 3.314 ± 0.03	1.504LysPhe: 1.504 ± 0.017	2.963LysGly: 2.963 ± 0.029	1.179LysHis: 1.179 ± 0.014	2.387LysIle: 2.387 ± 0.022	2.996LysLys: 2.996 ± 0.034	4.05LysLeu: 4.05 ± 0.029	1.065LysMet: 1.065 ± 0.013	1.638LysAsn: 1.638 ± 0.018	2.581LysPro: 2.581 ± 0.022	1.855LysGln: 1.855 ± 0.019	3.333LysArg: 3.333 ± 0.028	3.397LysSer: 3.397 ± 0.026	2.725LysThr: 2.725 ± 0.022	2.874LysVal: 2.874 ± 0.022	0.721LysTrp: 0.721 ± 0.012	1.427LysTyr: 1.427 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.013LeuAla: 8.013 ± 0.039	1.327LeuCys: 1.327 ± 0.016	5.23LeuAsp: 5.23 ± 0.032	5.613LeuGlu: 5.613 ± 0.035	3.418LeuPhe: 3.418 ± 0.025	6.13LeuGly: 6.13 ± 0.034	2.31LeuHis: 2.31 ± 0.021	4.086LeuIle: 4.086 ± 0.028	4.234LeuLys: 4.234 ± 0.03	8.628LeuLeu: 8.628 ± 0.044	1.877LeuMet: 1.877 ± 0.018	3.237LeuAsn: 3.237 ± 0.023	5.489LeuPro: 5.489 ± 0.036	3.955LeuGln: 3.955 ± 0.028	5.874LeuArg: 5.874 ± 0.035	7.287LeuSer: 7.287 ± 0.045	4.905LeuThr: 4.905 ± 0.029	5.565LeuVal: 5.565 ± 0.038	1.287LeuTrp: 1.287 ± 0.015	2.431LeuTyr: 2.431 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.295MetAla: 2.295 ± 0.023	0.263MetCys: 0.263 ± 0.007	1.224MetAsp: 1.224 ± 0.016	1.228MetGlu: 1.228 ± 0.014	0.768MetPhe: 0.768 ± 0.011	1.504MetGly: 1.504 ± 0.017	0.508MetHis: 0.508 ± 0.008	1.045MetIle: 1.045 ± 0.011	1.028MetLys: 1.028 ± 0.012	1.934MetLeu: 1.934 ± 0.017	0.563MetMet: 0.563 ± 0.01	0.799MetAsn: 0.799 ± 0.012	1.293MetPro: 1.293 ± 0.014	0.882MetGln: 0.882 ± 0.012	1.255MetArg: 1.255 ± 0.013	1.876MetSer: 1.876 ± 0.017	1.358MetThr: 1.358 ± 0.015	1.367MetVal: 1.367 ± 0.013	0.265MetTrp: 0.265 ± 0.007	0.545MetTyr: 0.545 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.205AsnAla: 3.205 ± 0.021	0.454AsnCys: 0.454 ± 0.009	1.901AsnAsp: 1.901 ± 0.019	1.971AsnGlu: 1.971 ± 0.017	1.406AsnPhe: 1.406 ± 0.017	2.945AsnGly: 2.945 ± 0.03	0.879AsnHis: 0.879 ± 0.012	2.034AsnIle: 2.034 ± 0.016	1.467AsnLys: 1.467 ± 0.015	3.312AsnLeu: 3.312 ± 0.026	0.799AsnMet: 0.799 ± 0.011	1.421AsnAsn: 1.421 ± 0.018	2.409AsnPro: 2.409 ± 0.022	1.32AsnGln: 1.32 ± 0.015	1.904AsnArg: 1.904 ± 0.018	2.573AsnSer: 2.573 ± 0.023	2.077AsnThr: 2.077 ± 0.021	2.401AsnVal: 2.401 ± 0.018	0.567AsnTrp: 0.567 ± 0.012	1.054AsnTyr: 1.054 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	4.918ProAla: 4.918 ± 0.033	0.525ProCys: 0.525 ± 0.009	3.218ProAsp: 3.218 ± 0.023	3.785ProGlu: 3.785 ± 0.03	2.113ProPhe: 2.113 ± 0.017	3.971ProGly: 3.971 ± 0.027	1.324ProHis: 1.324 ± 0.015	2.554ProIle: 2.554 ± 0.022	2.604ProLys: 2.604 ± 0.02	4.837ProLeu: 4.837 ± 0.032	1.084ProMet: 1.084 ± 0.014	2.218ProAsn: 2.218 ± 0.02	4.968ProPro: 4.968 ± 0.056	2.512ProGln: 2.512 ± 0.03	3.371ProArg: 3.371 ± 0.03	5.723ProSer: 5.723 ± 0.04	3.863ProThr: 3.863 ± 0.027	3.505ProVal: 3.505 ± 0.026	0.777ProTrp: 0.777 ± 0.012	1.529ProTyr: 1.529 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.519GlnAla: 3.519 ± 0.028	0.463GlnCys: 0.463 ± 0.009	2.118GlnAsp: 2.118 ± 0.017	2.489GlnGlu: 2.489 ± 0.021	1.338GlnPhe: 1.338 ± 0.013	2.507GlnGly: 2.507 ± 0.022	1.11GlnHis: 1.11 ± 0.013	2.036GlnIle: 2.036 ± 0.019	2.037GlnLys: 2.037 ± 0.019	3.489GlnLeu: 3.489 ± 0.025	0.922GlnMet: 0.922 ± 0.013	1.601GlnAsn: 1.601 ± 0.018	2.518GlnPro: 2.518 ± 0.028	2.38GlnGln: 2.38 ± 0.039	2.738GlnArg: 2.738 ± 0.027	3.142GlnSer: 3.142 ± 0.025	2.329GlnThr: 2.329 ± 0.02	2.217GlnVal: 2.217 ± 0.018	0.594GlnTrp: 0.594 ± 0.01	1.182GlnTyr: 1.182 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.732ArgAla: 4.732 ± 0.028	0.72ArgCys: 0.72 ± 0.012	3.401ArgAsp: 3.401 ± 0.026	3.855ArgGlu: 3.855 ± 0.028	2.126ArgPhe: 2.126 ± 0.018	3.694ArgGly: 3.694 ± 0.03	1.649ArgHis: 1.649 ± 0.019	2.925ArgIle: 2.925 ± 0.023	3.486ArgLys: 3.486 ± 0.027	5.639ArgLeu: 5.639 ± 0.038	1.322ArgMet: 1.322 ± 0.016	2.204ArgAsn: 2.204 ± 0.018	3.591ArgPro: 3.591 ± 0.034	2.716ArgGln: 2.716 ± 0.022	5.128ArgArg: 5.128 ± 0.036	4.654ArgSer: 4.654 ± 0.036	3.321ArgThr: 3.321 ± 0.025	3.338ArgVal: 3.338 ± 0.026	1.001ArgTrp: 1.001 ± 0.013	1.741ArgTyr: 1.741 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.471SerAla: 6.471 ± 0.043	0.875SerCys: 0.875 ± 0.012	4.009SerAsp: 4.009 ± 0.029	4.03SerGlu: 4.03 ± 0.029	2.98SerPhe: 2.98 ± 0.024	5.352SerGly: 5.352 ± 0.032	1.914SerHis: 1.914 ± 0.018	3.964SerIle: 3.964 ± 0.028	3.586SerLys: 3.586 ± 0.029	7.134SerLeu: 7.134 ± 0.039	1.702SerMet: 1.702 ± 0.017	2.874SerAsn: 2.874 ± 0.025	5.328SerPro: 5.328 ± 0.043	3.253SerGln: 3.253 ± 0.025	4.884SerArg: 4.884 ± 0.038	8.308SerSer: 8.308 ± 0.068	5.489SerThr: 5.489 ± 0.036	4.471SerVal: 4.471 ± 0.027	1.173SerTrp: 1.173 ± 0.013	2.016SerTyr: 2.016 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.3ThrAla: 5.3 ± 0.03	0.726ThrCys: 0.726 ± 0.012	2.798ThrAsp: 2.798 ± 0.023	3.012ThrGlu: 3.012 ± 0.025	2.317ThrPhe: 2.317 ± 0.019	4.163ThrGly: 4.163 ± 0.031	1.251ThrHis: 1.251 ± 0.013	3.144ThrIle: 3.144 ± 0.024	2.581ThrLys: 2.581 ± 0.019	5.218ThrLeu: 5.218 ± 0.033	1.221ThrMet: 1.221 ± 0.015	2.122ThrAsn: 2.122 ± 0.018	4.091ThrPro: 4.091 ± 0.03	2.089ThrGln: 2.089 ± 0.021	3.109ThrArg: 3.109 ± 0.025	5.272ThrSer: 5.272 ± 0.042	4.381ThrThr: 4.381 ± 0.047	3.742ThrVal: 3.742 ± 0.029	0.895ThrTrp: 0.895 ± 0.012	1.608ThrTyr: 1.608 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.34ValAla: 5.34 ± 0.032	0.856ValCys: 0.856 ± 0.011	3.757ValAsp: 3.757 ± 0.029	3.91ValGlu: 3.91 ± 0.026	2.526ValPhe: 2.526 ± 0.021	4.143ValGly: 4.143 ± 0.029	1.462ValHis: 1.462 ± 0.016	3.06ValIle: 3.06 ± 0.029	2.904ValLys: 2.904 ± 0.023	5.721ValLeu: 5.721 ± 0.034	1.35ValMet: 1.35 ± 0.017	2.29ValAsn: 2.29 ± 0.021	3.598ValPro: 3.598 ± 0.026	2.453ValGln: 2.453 ± 0.019	3.517ValArg: 3.517 ± 0.024	4.55ValSer: 4.55 ± 0.03	3.509ValThr: 3.509 ± 0.026	4.45ValVal: 4.45 ± 0.03	0.895ValTrp: 0.895 ± 0.012	1.724ValTyr: 1.724 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.181TrpAla: 1.181 ± 0.015	0.218TrpCys: 0.218 ± 0.006	0.871TrpAsp: 0.871 ± 0.013	0.819TrpGlu: 0.819 ± 0.013	0.565TrpPhe: 0.565 ± 0.01	0.92TrpGly: 0.92 ± 0.014	0.397TrpHis: 0.397 ± 0.008	0.853TrpIle: 0.853 ± 0.01	0.831TrpLys: 0.831 ± 0.012	1.442TrpLeu: 1.442 ± 0.018	0.4TrpMet: 0.4 ± 0.009	0.627TrpAsn: 0.627 ± 0.01	0.649TrpPro: 0.649 ± 0.011	0.595TrpGln: 0.595 ± 0.01	1.028TrpArg: 1.028 ± 0.013	1.118TrpSer: 1.118 ± 0.015	0.999TrpThr: 0.999 ± 0.015	0.903TrpVal: 0.903 ± 0.011	0.293TrpTrp: 0.293 ± 0.008	0.485TrpTyr: 0.485 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.272TyrAla: 2.272 ± 0.02	0.444TyrCys: 0.444 ± 0.008	1.647TyrAsp: 1.647 ± 0.02	1.556TyrGlu: 1.556 ± 0.017	1.272TyrPhe: 1.272 ± 0.016	2.161TyrGly: 2.161 ± 0.021	0.789TyrHis: 0.789 ± 0.011	1.415TyrIle: 1.415 ± 0.014	1.077TyrLys: 1.077 ± 0.012	2.772TyrLeu: 2.772 ± 0.021	0.624TyrMet: 0.624 ± 0.009	1.087TyrAsn: 1.087 ± 0.015	1.535TyrPro: 1.535 ± 0.017	1.14TyrGln: 1.14 ± 0.014	1.645TyrArg: 1.645 ± 0.017	1.983TyrSer: 1.983 ± 0.019	1.594TyrThr: 1.594 ± 0.016	1.663TyrVal: 1.663 ± 0.018	0.457TyrTrp: 0.457 ± 0.009	0.928TyrTyr: 0.928 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13417 proteins (6277743 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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