Amino acid dipepetide frequency for Porcine stool-associated circular virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.197AlaAla: 8.197 ± 1.56
2.732AlaCys: 2.732 ± 0.093
6.831AlaAsp: 6.831 ± 0.687
8.197AlaGlu: 8.197 ± 0.279
1.366AlaPhe: 1.366 ± 0.966
0.0AlaGly: 0.0 ± 0.0
1.366AlaHis: 1.366 ± 0.966
1.366AlaIle: 1.366 ± 0.873
1.366AlaLys: 1.366 ± 0.873
1.366AlaLeu: 1.366 ± 0.873
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.366AlaPro: 1.366 ± 0.966
1.366AlaGln: 1.366 ± 0.873
6.831AlaArg: 6.831 ± 1.152
4.098AlaSer: 4.098 ± 0.78
4.098AlaThr: 4.098 ± 0.78
0.0AlaVal: 0.0 ± 0.0
4.098AlaTrp: 4.098 ± 2.899
2.732AlaTyr: 2.732 ± 1.746
0.0AlaXaa: 0.0 ± 0.0
Cys
1.366CysAla: 1.366 ± 0.873
0.0CysCys: 0.0 ± 0.0
1.366CysAsp: 1.366 ± 0.873
1.366CysGlu: 1.366 ± 0.873
0.0CysPhe: 0.0 ± 0.0
1.366CysGly: 1.366 ± 0.873
1.366CysHis: 1.366 ± 0.966
2.732CysIle: 2.732 ± 0.093
2.732CysLys: 2.732 ± 1.932
1.366CysLeu: 1.366 ± 0.873
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.732CysPro: 2.732 ± 0.093
0.0CysGln: 0.0 ± 0.0
1.366CysArg: 1.366 ± 0.966
2.732CysSer: 2.732 ± 0.093
2.732CysThr: 2.732 ± 1.746
2.732CysVal: 2.732 ± 0.093
1.366CysTrp: 1.366 ± 0.966
1.366CysTyr: 1.366 ± 0.966
0.0CysXaa: 0.0 ± 0.0
Asp
5.464AspAla: 5.464 ± 1.653
2.732AspCys: 2.732 ± 0.093
2.732AspAsp: 2.732 ± 1.932
4.098AspGlu: 4.098 ± 1.059
1.366AspPhe: 1.366 ± 0.966
6.831AspGly: 6.831 ± 1.152
1.366AspHis: 1.366 ± 0.873
4.098AspIle: 4.098 ± 0.78
5.464AspLys: 5.464 ± 2.025
13.661AspLeu: 13.661 ± 0.465
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
4.098AspPro: 4.098 ± 1.059
1.366AspGln: 1.366 ± 0.873
1.366AspArg: 1.366 ± 0.966
0.0AspSer: 0.0 ± 0.0
2.732AspThr: 2.732 ± 0.093
4.098AspVal: 4.098 ± 0.78
1.366AspTrp: 1.366 ± 0.966
2.732AspTyr: 2.732 ± 1.932
0.0AspXaa: 0.0 ± 0.0
Glu
2.732GluAla: 2.732 ± 1.932
1.366GluCys: 1.366 ± 0.966
2.732GluAsp: 2.732 ± 0.093
1.366GluGlu: 1.366 ± 0.966
2.732GluPhe: 2.732 ± 0.093
6.831GluGly: 6.831 ± 4.831
1.366GluHis: 1.366 ± 0.966
1.366GluIle: 1.366 ± 0.966
1.366GluLys: 1.366 ± 0.966
2.732GluLeu: 2.732 ± 0.093
0.0GluMet: 0.0 ± 0.699
2.732GluAsn: 2.732 ± 1.932
4.098GluPro: 4.098 ± 2.899
1.366GluGln: 1.366 ± 0.966
4.098GluArg: 4.098 ± 2.62
0.0GluSer: 0.0 ± 0.0
5.464GluThr: 5.464 ± 0.186
2.732GluVal: 2.732 ± 1.932
2.732GluTrp: 2.732 ± 0.093
4.098GluTyr: 4.098 ± 0.78
0.0GluXaa: 0.0 ± 0.0
Phe
1.366PheAla: 1.366 ± 0.966
1.366PheCys: 1.366 ± 0.873
2.732PheAsp: 2.732 ± 1.932
1.366PheGlu: 1.366 ± 0.966
1.366PhePhe: 1.366 ± 0.966
2.732PheGly: 2.732 ± 1.932
0.0PheHis: 0.0 ± 0.0
1.366PheIle: 1.366 ± 0.966
1.366PheLys: 1.366 ± 0.966
2.732PheLeu: 2.732 ± 0.093
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
2.732PhePro: 2.732 ± 0.093
0.0PheGln: 0.0 ± 0.0
4.098PheArg: 4.098 ± 1.059
0.0PheSer: 0.0 ± 0.0
5.464PheThr: 5.464 ± 1.653
1.366PheVal: 1.366 ± 0.873
1.366PheTrp: 1.366 ± 0.873
1.366PheTyr: 1.366 ± 0.966
0.0PheXaa: 0.0 ± 0.0
Gly
4.098GlyAla: 4.098 ± 2.899
0.0GlyCys: 0.0 ± 0.0
5.464GlyAsp: 5.464 ± 0.186
5.464GlyGlu: 5.464 ± 2.025
2.732GlyPhe: 2.732 ± 0.093
6.831GlyGly: 6.831 ± 2.527
0.0GlyHis: 0.0 ± 0.0
1.366GlyIle: 1.366 ± 0.873
4.098GlyLys: 4.098 ± 1.059
6.831GlyLeu: 6.831 ± 1.152
1.366GlyMet: 1.366 ± 0.873
1.366GlyAsn: 1.366 ± 0.873
2.732GlyPro: 2.732 ± 0.093
4.098GlyGln: 4.098 ± 0.78
8.197GlyArg: 8.197 ± 0.279
8.197GlySer: 8.197 ± 0.279
5.464GlyThr: 5.464 ± 2.025
4.098GlyVal: 4.098 ± 0.78
2.732GlyTrp: 2.732 ± 1.746
2.732GlyTyr: 2.732 ± 1.932
0.0GlyXaa: 0.0 ± 0.0
His
1.366HisAla: 1.366 ± 0.873
1.366HisCys: 1.366 ± 0.966
5.464HisAsp: 5.464 ± 2.025
0.0HisGlu: 0.0 ± 0.0
1.366HisPhe: 1.366 ± 0.966
0.0HisGly: 0.0 ± 0.0
1.366HisHis: 1.366 ± 0.966
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.732HisLeu: 2.732 ± 0.093
0.0HisMet: 0.0 ± 0.0
1.366HisAsn: 1.366 ± 0.873
1.366HisPro: 1.366 ± 0.873
0.0HisGln: 0.0 ± 0.0
2.732HisArg: 2.732 ± 0.093
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.732HisVal: 2.732 ± 0.093
0.0HisTrp: 0.0 ± 0.0
1.366HisTyr: 1.366 ± 0.966
0.0HisXaa: 0.0 ± 0.0
Ile
1.366IleAla: 1.366 ± 0.966
1.366IleCys: 1.366 ± 0.873
6.831IleAsp: 6.831 ± 0.687
2.732IleGlu: 2.732 ± 1.932
1.366IlePhe: 1.366 ± 0.873
5.464IleGly: 5.464 ± 1.653
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
0.0IleLys: 0.0 ± 0.0
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.732IlePro: 2.732 ± 0.093
1.366IleGln: 1.366 ± 0.873
4.098IleArg: 4.098 ± 2.62
4.098IleSer: 4.098 ± 0.78
2.732IleThr: 2.732 ± 0.093
2.732IleVal: 2.732 ± 0.093
0.0IleTrp: 0.0 ± 0.0
2.732IleTyr: 2.732 ± 0.093
0.0IleXaa: 0.0 ± 0.0
Lys
4.098LysAla: 4.098 ± 0.78
1.366LysCys: 1.366 ± 0.873
2.732LysAsp: 2.732 ± 0.093
4.098LysGlu: 4.098 ± 2.899
2.732LysPhe: 2.732 ± 1.746
2.732LysGly: 2.732 ± 0.093
2.732LysHis: 2.732 ± 0.093
1.366LysIle: 1.366 ± 0.873
2.732LysLys: 2.732 ± 1.932
4.098LysLeu: 4.098 ± 2.62
1.366LysMet: 1.366 ± 0.873
4.098LysAsn: 4.098 ± 1.059
4.098LysPro: 4.098 ± 1.059
2.732LysGln: 2.732 ± 1.932
1.366LysArg: 1.366 ± 0.966
5.464LysSer: 5.464 ± 1.653
2.732LysThr: 2.732 ± 1.932
5.464LysVal: 5.464 ± 2.025
1.366LysTrp: 1.366 ± 0.966
1.366LysTyr: 1.366 ± 0.966
0.0LysXaa: 0.0 ± 0.0
Leu
6.831LeuAla: 6.831 ± 1.152
1.366LeuCys: 1.366 ± 0.873
1.366LeuAsp: 1.366 ± 0.966
1.366LeuGlu: 1.366 ± 0.873
2.732LeuPhe: 2.732 ± 0.093
4.098LeuGly: 4.098 ± 1.059
0.0LeuHis: 0.0 ± 0.0
5.464LeuIle: 5.464 ± 0.186
2.732LeuLys: 2.732 ± 0.093
4.098LeuLeu: 4.098 ± 0.78
1.366LeuMet: 1.366 ± 0.966
1.366LeuAsn: 1.366 ± 0.873
6.831LeuPro: 6.831 ± 4.366
2.732LeuGln: 2.732 ± 1.932
1.366LeuArg: 1.366 ± 0.873
6.831LeuSer: 6.831 ± 2.527
2.732LeuThr: 2.732 ± 0.093
1.366LeuVal: 1.366 ± 0.966
5.464LeuTrp: 5.464 ± 0.186
8.197LeuTyr: 8.197 ± 1.56
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
6.831MetAsp: 6.831 ± 1.152
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.366MetGly: 1.366 ± 0.873
2.732MetHis: 2.732 ± 0.093
2.732MetIle: 2.732 ± 1.932
0.0MetLys: 0.0 ± 0.0
2.732MetLeu: 2.732 ± 0.093
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.366MetPro: 1.366 ± 0.966
0.0MetGln: 0.0 ± 0.0
2.732MetArg: 2.732 ± 1.746
0.0MetSer: 0.0 ± 0.0
1.366MetThr: 1.366 ± 0.873
1.366MetVal: 1.366 ± 0.873
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.366AsnAla: 1.366 ± 0.873
1.366AsnCys: 1.366 ± 0.966
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
4.098AsnGly: 4.098 ± 2.62
2.732AsnHis: 2.732 ± 1.746
0.0AsnIle: 0.0 ± 0.0
1.366AsnLys: 1.366 ± 0.966
1.366AsnLeu: 1.366 ± 0.873
2.732AsnMet: 2.732 ± 0.093
0.0AsnAsn: 0.0 ± 0.0
6.831AsnPro: 6.831 ± 2.992
1.366AsnGln: 1.366 ± 0.966
1.366AsnArg: 1.366 ± 0.873
0.0AsnSer: 0.0 ± 0.0
2.732AsnThr: 2.732 ± 1.746
0.0AsnVal: 0.0 ± 0.0
1.366AsnTrp: 1.366 ± 0.873
2.732AsnTyr: 2.732 ± 0.093
0.0AsnXaa: 0.0 ± 0.0
Pro
1.366ProAla: 1.366 ± 0.966
0.0ProCys: 0.0 ± 0.0
4.098ProAsp: 4.098 ± 1.059
10.929ProGlu: 10.929 ± 4.051
2.732ProPhe: 2.732 ± 1.932
2.732ProGly: 2.732 ± 1.932
1.366ProHis: 1.366 ± 0.873
1.366ProIle: 1.366 ± 0.873
8.197ProLys: 8.197 ± 0.279
4.098ProLeu: 4.098 ± 0.78
2.732ProMet: 2.732 ± 1.404
0.0ProAsn: 0.0 ± 0.0
4.098ProPro: 4.098 ± 0.78
4.098ProGln: 4.098 ± 1.059
4.098ProArg: 4.098 ± 2.899
1.366ProSer: 1.366 ± 0.873
4.098ProThr: 4.098 ± 2.62
6.831ProVal: 6.831 ± 2.527
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.366GlnCys: 1.366 ± 0.966
4.098GlnAsp: 4.098 ± 1.059
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
2.732GlnGly: 2.732 ± 1.932
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.732GlnLeu: 2.732 ± 0.093
2.732GlnMet: 2.732 ± 0.093
1.366GlnAsn: 1.366 ± 0.873
1.366GlnPro: 1.366 ± 0.873
1.366GlnGln: 1.366 ± 0.873
4.098GlnArg: 4.098 ± 1.059
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
4.098GlnVal: 4.098 ± 0.78
0.0GlnTrp: 0.0 ± 0.0
1.366GlnTyr: 1.366 ± 0.873
0.0GlnXaa: 0.0 ± 0.0
Arg
5.464ArgAla: 5.464 ± 0.186
4.098ArgCys: 4.098 ± 0.78
0.0ArgAsp: 0.0 ± 0.0
2.732ArgGlu: 2.732 ± 1.932
2.732ArgPhe: 2.732 ± 1.932
5.464ArgGly: 5.464 ± 0.186
1.366ArgHis: 1.366 ± 0.966
1.366ArgIle: 1.366 ± 0.873
6.831ArgLys: 6.831 ± 0.687
5.464ArgLeu: 5.464 ± 1.653
4.098ArgMet: 4.098 ± 1.059
6.831ArgAsn: 6.831 ± 2.527
2.732ArgPro: 2.732 ± 0.093
1.366ArgGln: 1.366 ± 0.873
23.224ArgArg: 23.224 ± 7.487
5.464ArgSer: 5.464 ± 1.653
4.098ArgThr: 4.098 ± 1.059
1.366ArgVal: 1.366 ± 0.966
0.0ArgTrp: 0.0 ± 0.0
4.098ArgTyr: 4.098 ± 2.62
0.0ArgXaa: 0.0 ± 0.0
Ser
2.732SerAla: 2.732 ± 1.746
0.0SerCys: 0.0 ± 0.0
4.098SerAsp: 4.098 ± 2.62
0.0SerGlu: 0.0 ± 0.0
2.732SerPhe: 2.732 ± 1.746
8.197SerGly: 8.197 ± 0.279
1.366SerHis: 1.366 ± 0.966
5.464SerIle: 5.464 ± 1.653
1.366SerLys: 1.366 ± 0.873
1.366SerLeu: 1.366 ± 0.873
1.366SerMet: 1.366 ± 0.873
1.366SerAsn: 1.366 ± 0.966
0.0SerPro: 0.0 ± 0.0
2.732SerGln: 2.732 ± 1.746
1.366SerArg: 1.366 ± 0.873
2.732SerSer: 2.732 ± 1.746
2.732SerThr: 2.732 ± 0.093
4.098SerVal: 4.098 ± 0.78
2.732SerTrp: 2.732 ± 1.746
5.464SerTyr: 5.464 ± 1.653
0.0SerXaa: 0.0 ± 0.0
Thr
6.831ThrAla: 6.831 ± 0.687
4.098ThrCys: 4.098 ± 1.059
2.732ThrAsp: 2.732 ± 0.093
0.0ThrGlu: 0.0 ± 0.0
2.732ThrPhe: 2.732 ± 0.093
5.464ThrGly: 5.464 ± 1.653
2.732ThrHis: 2.732 ± 0.093
4.098ThrIle: 4.098 ± 0.78
5.464ThrLys: 5.464 ± 1.653
2.732ThrLeu: 2.732 ± 0.093
1.366ThrMet: 1.366 ± 0.966
4.098ThrAsn: 4.098 ± 1.059
0.0ThrPro: 0.0 ± 0.0
0.0ThrGln: 0.0 ± 0.0
1.366ThrArg: 1.366 ± 0.966
2.732ThrSer: 2.732 ± 1.746
1.366ThrThr: 1.366 ± 0.966
6.831ThrVal: 6.831 ± 0.687
2.732ThrTrp: 2.732 ± 1.746
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.366ValAla: 1.366 ± 0.873
1.366ValCys: 1.366 ± 0.873
2.732ValAsp: 2.732 ± 1.932
5.464ValGlu: 5.464 ± 2.025
1.366ValPhe: 1.366 ± 0.966
4.098ValGly: 4.098 ± 1.059
0.0ValHis: 0.0 ± 0.0
4.098ValIle: 4.098 ± 0.78
4.098ValLys: 4.098 ± 0.78
2.732ValLeu: 2.732 ± 1.932
2.732ValMet: 2.732 ± 0.093
1.366ValAsn: 1.366 ± 0.873
6.831ValPro: 6.831 ± 2.527
0.0ValGln: 0.0 ± 0.0
5.464ValArg: 5.464 ± 1.653
5.464ValSer: 5.464 ± 3.493
5.464ValThr: 5.464 ± 0.186
10.929ValVal: 10.929 ± 1.467
2.732ValTrp: 2.732 ± 0.093
2.732ValTyr: 2.732 ± 1.932
0.0ValXaa: 0.0 ± 0.0
Trp
1.366TrpAla: 1.366 ± 0.873
1.366TrpCys: 1.366 ± 0.873
1.366TrpAsp: 1.366 ± 0.873
0.0TrpGlu: 0.0 ± 0.0
1.366TrpPhe: 1.366 ± 0.966
1.366TrpGly: 1.366 ± 0.966
1.366TrpHis: 1.366 ± 0.966
1.366TrpIle: 1.366 ± 0.873
2.732TrpLys: 2.732 ± 0.093
1.366TrpLeu: 1.366 ± 0.966
0.0TrpMet: 0.0 ± 0.0
2.732TrpAsn: 2.732 ± 0.093
2.732TrpPro: 2.732 ± 0.093
1.366TrpGln: 1.366 ± 0.966
4.098TrpArg: 4.098 ± 0.78
1.366TrpSer: 1.366 ± 0.873
1.366TrpThr: 1.366 ± 0.873
2.732TrpVal: 2.732 ± 0.093
0.0TrpTrp: 0.0 ± 0.0
2.732TrpTyr: 2.732 ± 0.093
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.366TyrCys: 1.366 ± 0.966
1.366TyrAsp: 1.366 ± 0.966
4.098TyrGlu: 4.098 ± 1.059
1.366TyrPhe: 1.366 ± 0.966
5.464TyrGly: 5.464 ± 1.653
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
6.831TyrLys: 6.831 ± 1.152
4.098TyrLeu: 4.098 ± 0.78
0.0TyrMet: 0.0 ± 0.0
2.732TyrAsn: 2.732 ± 1.746
5.464TyrPro: 5.464 ± 2.025
0.0TyrGln: 0.0 ± 0.0
5.464TyrArg: 5.464 ± 1.653
1.366TyrSer: 1.366 ± 0.873
0.0TyrThr: 0.0 ± 0.0
5.464TyrVal: 5.464 ± 0.186
2.732TyrTrp: 2.732 ± 0.093
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (733 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski