Amino acid dipepetide frequency for Chryseobacterium sp. 3008163

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.9AlaAla: 3.9 ± 0.09	0.479AlaCys: 0.479 ± 0.023	3.334AlaAsp: 3.334 ± 0.056	4.12AlaGlu: 4.12 ± 0.073	2.997AlaPhe: 2.997 ± 0.057	4.291AlaGly: 4.291 ± 0.077	0.978AlaHis: 0.978 ± 0.031	4.643AlaIle: 4.643 ± 0.077	4.789AlaLys: 4.789 ± 0.076	5.473AlaLeu: 5.473 ± 0.077	1.472AlaMet: 1.472 ± 0.039	3.427AlaAsn: 3.427 ± 0.067	1.707AlaPro: 1.707 ± 0.048	2.471AlaGln: 2.471 ± 0.05	1.674AlaArg: 1.674 ± 0.037	3.94AlaSer: 3.94 ± 0.073	3.54AlaThr: 3.54 ± 0.075	4.023AlaVal: 4.023 ± 0.069	0.592AlaTrp: 0.592 ± 0.023	2.187AlaTyr: 2.187 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.407CysAla: 0.407 ± 0.021	0.098CysCys: 0.098 ± 0.009	0.376CysAsp: 0.376 ± 0.019	0.427CysGlu: 0.427 ± 0.019	0.446CysPhe: 0.446 ± 0.022	0.615CysGly: 0.615 ± 0.024	0.166CysHis: 0.166 ± 0.014	0.581CysIle: 0.581 ± 0.022	0.476CysLys: 0.476 ± 0.019	0.641CysLeu: 0.641 ± 0.022	0.166CysMet: 0.166 ± 0.013	0.424CysAsn: 0.424 ± 0.018	0.312CysPro: 0.312 ± 0.021	0.22CysGln: 0.22 ± 0.014	0.195CysArg: 0.195 ± 0.013	0.534CysSer: 0.534 ± 0.022	0.429CysThr: 0.429 ± 0.02	0.414CysVal: 0.414 ± 0.019	0.063CysTrp: 0.063 ± 0.007	0.299CysTyr: 0.299 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.306AspAla: 3.306 ± 0.057	0.387AspCys: 0.387 ± 0.021	2.791AspAsp: 2.791 ± 0.05	3.984AspGlu: 3.984 ± 0.07	3.963AspPhe: 3.963 ± 0.053	3.521AspGly: 3.521 ± 0.06	0.915AspHis: 0.915 ± 0.032	4.169AspIle: 4.169 ± 0.064	4.396AspLys: 4.396 ± 0.067	5.126AspLeu: 5.126 ± 0.083	1.048AspMet: 1.048 ± 0.03	3.008AspAsn: 3.008 ± 0.059	1.597AspPro: 1.597 ± 0.042	1.777AspGln: 1.777 ± 0.038	1.721AspArg: 1.721 ± 0.044	3.16AspSer: 3.16 ± 0.055	2.238AspThr: 2.238 ± 0.042	3.322AspVal: 3.322 ± 0.062	0.774AspTrp: 0.774 ± 0.024	2.834AspTyr: 2.834 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	3.668GluAla: 3.668 ± 0.077	0.363GluCys: 0.363 ± 0.018	3.453GluAsp: 3.453 ± 0.059	4.718GluGlu: 4.718 ± 0.092	3.284GluPhe: 3.284 ± 0.057	3.33GluGly: 3.33 ± 0.063	0.966GluHis: 0.966 ± 0.031	6.141GluIle: 6.141 ± 0.104	7.025GluLys: 7.025 ± 0.107	5.614GluLeu: 5.614 ± 0.08	1.72GluMet: 1.72 ± 0.039	5.675GluAsn: 5.675 ± 0.083	1.345GluPro: 1.345 ± 0.034	2.095GluGln: 2.095 ± 0.043	2.239GluArg: 2.239 ± 0.048	3.472GluSer: 3.472 ± 0.059	3.419GluThr: 3.419 ± 0.058	3.902GluVal: 3.902 ± 0.063	0.662GluTrp: 0.662 ± 0.024	2.512GluTyr: 2.512 ± 0.046	0.0GluXaa: 0.0 ± 0.0
Phe	3.373PheAla: 3.373 ± 0.058	0.47PheCys: 0.47 ± 0.022	3.206PheAsp: 3.206 ± 0.046	3.431PheGlu: 3.431 ± 0.07	2.988PhePhe: 2.988 ± 0.054	3.722PheGly: 3.722 ± 0.063	0.955PheHis: 0.955 ± 0.031	4.221PheIle: 4.221 ± 0.074	3.989PheLys: 3.989 ± 0.072	5.025PheLeu: 5.025 ± 0.079	1.186PheMet: 1.186 ± 0.034	3.365PheAsn: 3.365 ± 0.057	1.894PhePro: 1.894 ± 0.04	1.719PheGln: 1.719 ± 0.043	1.725PheArg: 1.725 ± 0.045	4.437PheSer: 4.437 ± 0.064	3.312PheThr: 3.312 ± 0.064	3.092PheVal: 3.092 ± 0.058	0.616PheTrp: 0.616 ± 0.026	2.47PheTyr: 2.47 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	3.79GlyAla: 3.79 ± 0.067	0.547GlyCys: 0.547 ± 0.023	2.958GlyAsp: 2.958 ± 0.055	3.459GlyGlu: 3.459 ± 0.061	3.651GlyPhe: 3.651 ± 0.062	4.476GlyGly: 4.476 ± 0.084	0.962GlyHis: 0.962 ± 0.032	5.36GlyIle: 5.36 ± 0.071	5.536GlyLys: 5.536 ± 0.086	5.276GlyLeu: 5.276 ± 0.075	1.558GlyMet: 1.558 ± 0.041	4.265GlyAsn: 4.265 ± 0.081	1.142GlyPro: 1.142 ± 0.037	1.908GlyGln: 1.908 ± 0.045	1.942GlyArg: 1.942 ± 0.045	4.069GlySer: 4.069 ± 0.073	4.005GlyThr: 4.005 ± 0.085	3.915GlyVal: 3.915 ± 0.064	0.756GlyTrp: 0.756 ± 0.029	2.75GlyTyr: 2.75 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	0.839HisAla: 0.839 ± 0.032	0.139HisCys: 0.139 ± 0.009	0.808HisAsp: 0.808 ± 0.028	0.951HisGlu: 0.951 ± 0.033	1.173HisPhe: 1.173 ± 0.035	0.961HisGly: 0.961 ± 0.031	0.462HisHis: 0.462 ± 0.022	1.227HisIle: 1.227 ± 0.034	1.106HisLys: 1.106 ± 0.035	1.696HisLeu: 1.696 ± 0.048	0.302HisMet: 0.302 ± 0.017	0.88HisAsn: 0.88 ± 0.027	0.79HisPro: 0.79 ± 0.031	0.753HisGln: 0.753 ± 0.025	0.576HisArg: 0.576 ± 0.022	1.124HisSer: 1.124 ± 0.034	0.842HisThr: 0.842 ± 0.026	0.731HisVal: 0.731 ± 0.025	0.216HisTrp: 0.216 ± 0.014	0.79HisTyr: 0.79 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.14IleAla: 5.14 ± 0.077	0.687IleCys: 0.687 ± 0.028	4.66IleAsp: 4.66 ± 0.071	5.162IleGlu: 5.162 ± 0.078	4.25IlePhe: 4.25 ± 0.066	4.863IleGly: 4.863 ± 0.08	1.299IleHis: 1.299 ± 0.036	6.486IleIle: 6.486 ± 0.097	6.097IleLys: 6.097 ± 0.084	7.626IleLeu: 7.626 ± 0.102	1.436IleMet: 1.436 ± 0.038	5.055IleAsn: 5.055 ± 0.072	3.333IlePro: 3.333 ± 0.059	2.715IleGln: 2.715 ± 0.055	2.307IleArg: 2.307 ± 0.05	6.311IleSer: 6.311 ± 0.067	4.568IleThr: 4.568 ± 0.075	4.54IleVal: 4.54 ± 0.068	0.717IleTrp: 0.717 ± 0.026	3.104IleTyr: 3.104 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	4.696LysAla: 4.696 ± 0.068	0.376LysCys: 0.376 ± 0.022	5.124LysAsp: 5.124 ± 0.074	6.162LysGlu: 6.162 ± 0.09	3.718LysPhe: 3.718 ± 0.064	4.381LysGly: 4.381 ± 0.062	1.233LysHis: 1.233 ± 0.04	7.698LysIle: 7.698 ± 0.087	7.71LysLys: 7.71 ± 0.097	6.756LysLeu: 6.756 ± 0.073	2.507LysMet: 2.507 ± 0.041	6.768LysAsn: 6.768 ± 0.088	2.606LysPro: 2.606 ± 0.053	2.554LysGln: 2.554 ± 0.044	2.438LysArg: 2.438 ± 0.046	5.135LysSer: 5.135 ± 0.079	5.039LysThr: 5.039 ± 0.073	4.836LysVal: 4.836 ± 0.064	0.817LysTrp: 0.817 ± 0.026	3.482LysTyr: 3.482 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	5.303LeuAla: 5.303 ± 0.074	0.674LeuCys: 0.674 ± 0.022	4.721LeuAsp: 4.721 ± 0.058	5.699LeuGlu: 5.699 ± 0.095	4.772LeuPhe: 4.772 ± 0.084	5.626LeuGly: 5.626 ± 0.082	1.401LeuHis: 1.401 ± 0.038	6.797LeuIle: 6.797 ± 0.088	8.174LeuLys: 8.174 ± 0.098	8.065LeuLeu: 8.065 ± 0.113	2.256LeuMet: 2.256 ± 0.041	5.921LeuAsn: 5.921 ± 0.087	3.528LeuPro: 3.528 ± 0.056	3.349LeuGln: 3.349 ± 0.056	2.829LeuArg: 2.829 ± 0.05	6.721LeuSer: 6.721 ± 0.079	4.859LeuThr: 4.859 ± 0.071	4.989LeuVal: 4.989 ± 0.076	0.838LeuTrp: 0.838 ± 0.027	3.137LeuTyr: 3.137 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	1.398MetAla: 1.398 ± 0.038	0.137MetCys: 0.137 ± 0.012	1.065MetAsp: 1.065 ± 0.03	1.482MetGlu: 1.482 ± 0.038	0.937MetPhe: 0.937 ± 0.032	1.388MetGly: 1.388 ± 0.039	0.365MetHis: 0.365 ± 0.017	1.857MetIle: 1.857 ± 0.048	2.656MetLys: 2.656 ± 0.042	1.96MetLeu: 1.96 ± 0.044	0.761MetMet: 0.761 ± 0.028	1.626MetAsn: 1.626 ± 0.031	0.833MetPro: 0.833 ± 0.029	0.828MetGln: 0.828 ± 0.026	0.793MetArg: 0.793 ± 0.031	1.53MetSer: 1.53 ± 0.037	1.301MetThr: 1.301 ± 0.038	1.322MetVal: 1.322 ± 0.037	0.159MetTrp: 0.159 ± 0.01	0.751MetTyr: 0.751 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.994AsnAla: 3.994 ± 0.064	0.442AsnCys: 0.442 ± 0.022	3.346AsnAsp: 3.346 ± 0.07	4.004AsnGlu: 4.004 ± 0.068	3.822AsnPhe: 3.822 ± 0.061	4.306AsnGly: 4.306 ± 0.082	1.164AsnHis: 1.164 ± 0.034	5.54AsnIle: 5.54 ± 0.067	4.608AsnLys: 4.608 ± 0.066	6.203AsnLeu: 6.203 ± 0.085	1.36AsnMet: 1.36 ± 0.036	4.429AsnAsn: 4.429 ± 0.088	3.025AsnPro: 3.025 ± 0.058	2.647AsnGln: 2.647 ± 0.045	1.985AsnArg: 1.985 ± 0.043	4.456AsnSer: 4.456 ± 0.085	3.581AsnThr: 3.581 ± 0.087	3.889AsnVal: 3.889 ± 0.07	0.804AsnTrp: 0.804 ± 0.028	3.161AsnTyr: 3.161 ± 0.069	0.0AsnXaa: 0.0 ± 0.0
Pro	2.087ProAla: 2.087 ± 0.052	0.201ProCys: 0.201 ± 0.013	1.971ProAsp: 1.971 ± 0.044	2.728ProGlu: 2.728 ± 0.055	1.821ProPhe: 1.821 ± 0.042	1.801ProGly: 1.801 ± 0.046	0.545ProHis: 0.545 ± 0.02	2.454ProIle: 2.454 ± 0.05	2.602ProLys: 2.602 ± 0.053	2.764ProLeu: 2.764 ± 0.047	0.773ProMet: 0.773 ± 0.032	2.308ProAsn: 2.308 ± 0.046	0.827ProPro: 0.827 ± 0.036	1.252ProGln: 1.252 ± 0.037	0.846ProArg: 0.846 ± 0.028	2.203ProSer: 2.203 ± 0.044	2.117ProThr: 2.117 ± 0.053	2.342ProVal: 2.342 ± 0.05	0.288ProTrp: 0.288 ± 0.017	1.359ProTyr: 1.359 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	1.8GlnAla: 1.8 ± 0.04	0.185GlnCys: 0.185 ± 0.012	1.626GlnAsp: 1.626 ± 0.036	2.135GlnGlu: 2.135 ± 0.052	1.892GlnPhe: 1.892 ± 0.041	1.742GlnGly: 1.742 ± 0.043	0.594GlnHis: 0.594 ± 0.022	2.96GlnIle: 2.96 ± 0.049	3.463GlnLys: 3.463 ± 0.064	3.247GlnLeu: 3.247 ± 0.051	0.904GlnMet: 0.904 ± 0.028	2.915GlnAsn: 2.915 ± 0.057	1.118GlnPro: 1.118 ± 0.032	1.515GlnGln: 1.515 ± 0.041	1.166GlnArg: 1.166 ± 0.032	2.248GlnSer: 2.248 ± 0.048	2.055GlnThr: 2.055 ± 0.048	1.841GlnVal: 1.841 ± 0.042	0.376GlnTrp: 0.376 ± 0.021	1.521GlnTyr: 1.521 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	1.656ArgAla: 1.656 ± 0.044	0.189ArgCys: 0.189 ± 0.013	1.57ArgAsp: 1.57 ± 0.041	2.101ArgGlu: 2.101 ± 0.048	1.713ArgPhe: 1.713 ± 0.036	1.644ArgGly: 1.644 ± 0.04	0.486ArgHis: 0.486 ± 0.02	2.688ArgIle: 2.688 ± 0.048	2.921ArgLys: 2.921 ± 0.054	2.717ArgLeu: 2.717 ± 0.051	0.846ArgMet: 0.846 ± 0.022	2.169ArgAsn: 2.169 ± 0.048	0.989ArgPro: 0.989 ± 0.028	1.029ArgGln: 1.029 ± 0.035	1.205ArgArg: 1.205 ± 0.038	1.789ArgSer: 1.789 ± 0.042	1.602ArgThr: 1.602 ± 0.043	1.772ArgVal: 1.772 ± 0.036	0.327ArgTrp: 0.327 ± 0.018	1.276ArgTyr: 1.276 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.135SerAla: 4.135 ± 0.063	0.642SerCys: 0.642 ± 0.022	3.7SerAsp: 3.7 ± 0.06	4.526SerGlu: 4.526 ± 0.061	4.009SerPhe: 4.009 ± 0.068	4.816SerGly: 4.816 ± 0.066	1.085SerHis: 1.085 ± 0.03	5.061SerIle: 5.061 ± 0.067	5.31SerLys: 5.31 ± 0.074	6.113SerLeu: 6.113 ± 0.083	1.409SerMet: 1.409 ± 0.034	3.951SerAsn: 3.951 ± 0.077	2.174SerPro: 2.174 ± 0.045	2.541SerGln: 2.541 ± 0.052	1.917SerArg: 1.917 ± 0.043	4.58SerSer: 4.58 ± 0.091	3.783SerThr: 3.783 ± 0.075	4.301SerVal: 4.301 ± 0.06	0.72SerTrp: 0.72 ± 0.029	2.873SerTyr: 2.873 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	3.951ThrAla: 3.951 ± 0.082	0.345ThrCys: 0.345 ± 0.019	3.168ThrAsp: 3.168 ± 0.048	3.679ThrGlu: 3.679 ± 0.062	3.012ThrPhe: 3.012 ± 0.052	4.013ThrGly: 4.013 ± 0.079	0.894ThrHis: 0.894 ± 0.026	4.251ThrIle: 4.251 ± 0.069	4.132ThrLys: 4.132 ± 0.062	4.977ThrLeu: 4.977 ± 0.068	0.982ThrMet: 0.982 ± 0.032	3.358ThrAsn: 3.358 ± 0.07	2.309ThrPro: 2.309 ± 0.05	1.935ThrGln: 1.935 ± 0.047	1.415ThrArg: 1.415 ± 0.033	3.85ThrSer: 3.85 ± 0.078	3.605ThrThr: 3.605 ± 0.094	3.724ThrVal: 3.724 ± 0.076	0.589ThrTrp: 0.589 ± 0.026	2.345ThrTyr: 2.345 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	3.745ValAla: 3.745 ± 0.065	0.493ValCys: 0.493 ± 0.022	3.165ValAsp: 3.165 ± 0.058	3.785ValGlu: 3.785 ± 0.063	3.412ValPhe: 3.412 ± 0.062	3.616ValGly: 3.616 ± 0.065	0.869ValHis: 0.869 ± 0.029	4.561ValIle: 4.561 ± 0.074	4.921ValLys: 4.921 ± 0.075	5.444ValLeu: 5.444 ± 0.066	1.384ValMet: 1.384 ± 0.037	3.704ValAsn: 3.704 ± 0.074	2.044ValPro: 2.044 ± 0.043	1.835ValGln: 1.835 ± 0.044	1.853ValArg: 1.853 ± 0.038	4.456ValSer: 4.456 ± 0.063	3.298ValThr: 3.298 ± 0.069	3.73ValVal: 3.73 ± 0.07	0.633ValTrp: 0.633 ± 0.024	2.38ValTyr: 2.38 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.591TrpAla: 0.591 ± 0.02	0.082TrpCys: 0.082 ± 0.007	0.618TrpAsp: 0.618 ± 0.024	0.686TrpGlu: 0.686 ± 0.023	0.57TrpPhe: 0.57 ± 0.024	0.698TrpGly: 0.698 ± 0.031	0.191TrpHis: 0.191 ± 0.013	0.764TrpIle: 0.764 ± 0.028	1.023TrpLys: 1.023 ± 0.035	0.933TrpLeu: 0.933 ± 0.029	0.35TrpMet: 0.35 ± 0.019	0.76TrpAsn: 0.76 ± 0.028	0.183TrpPro: 0.183 ± 0.014	0.409TrpGln: 0.409 ± 0.02	0.339TrpArg: 0.339 ± 0.016	0.657TrpSer: 0.657 ± 0.026	0.583TrpThr: 0.583 ± 0.025	0.584TrpVal: 0.584 ± 0.022	0.153TrpTrp: 0.153 ± 0.011	0.431TrpTyr: 0.431 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.048	0.352TyrCys: 0.352 ± 0.017	2.373TyrAsp: 2.373 ± 0.053	2.364TyrGlu: 2.364 ± 0.05	2.767TyrPhe: 2.767 ± 0.054	2.517TyrGly: 2.517 ± 0.051	0.837TyrHis: 0.837 ± 0.028	2.898TyrIle: 2.898 ± 0.059	3.108TyrLys: 3.108 ± 0.057	4.001TyrLeu: 4.001 ± 0.06	0.731TyrMet: 0.731 ± 0.021	2.758TyrAsn: 2.758 ± 0.06	1.533TyrPro: 1.533 ± 0.038	1.752TyrGln: 1.752 ± 0.037	1.522TyrArg: 1.522 ± 0.037	2.972TyrSer: 2.972 ± 0.054	2.356TyrThr: 2.356 ± 0.058	2.057TyrVal: 2.057 ± 0.04	0.505TyrTrp: 0.505 ± 0.021	2.121TyrTyr: 2.121 ± 0.055	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3789 proteins (1171329 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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