Amino acid dipepetide frequency for Sewage-associated circular DNA virus-26

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.899AlaAla: 2.899 ± 1.806
0.0AlaCys: 0.0 ± 0.0
1.449AlaAsp: 1.449 ± 1.392
4.348AlaGlu: 4.348 ± 2.709
2.899AlaPhe: 2.899 ± 2.784
2.899AlaGly: 2.899 ± 1.806
0.0AlaHis: 0.0 ± 0.0
1.449AlaIle: 1.449 ± 1.392
5.797AlaLys: 5.797 ± 3.612
8.696AlaLeu: 8.696 ± 1.467
1.449AlaMet: 1.449 ± 0.833
7.246AlaAsn: 7.246 ± 0.075
5.797AlaPro: 5.797 ± 0.978
0.0AlaGln: 0.0 ± 0.0
1.449AlaArg: 1.449 ± 1.392
2.899AlaSer: 2.899 ± 2.784
4.348AlaThr: 4.348 ± 4.176
1.449AlaVal: 1.449 ± 0.903
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
4.348CysAsp: 4.348 ± 2.709
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.449CysGly: 1.449 ± 0.903
1.449CysHis: 1.449 ± 0.903
0.0CysIle: 0.0 ± 0.0
2.899CysLys: 2.899 ± 0.489
1.449CysLeu: 1.449 ± 1.392
1.449CysMet: 1.449 ± 0.903
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.449CysSer: 1.449 ± 1.392
0.0CysThr: 0.0 ± 0.0
1.449CysVal: 1.449 ± 1.392
0.0CysTrp: 0.0 ± 0.0
1.449CysTyr: 1.449 ± 0.903
0.0CysXaa: 0.0 ± 0.0
Asp
2.899AspAla: 2.899 ± 2.784
1.449AspCys: 1.449 ± 0.903
2.899AspAsp: 2.899 ± 1.806
8.696AspGlu: 8.696 ± 3.123
2.899AspPhe: 2.899 ± 0.489
2.899AspGly: 2.899 ± 0.489
1.449AspHis: 1.449 ± 0.903
5.797AspIle: 5.797 ± 1.317
2.899AspLys: 2.899 ± 0.489
4.348AspLeu: 4.348 ± 2.709
1.449AspMet: 1.449 ± 1.425
0.0AspAsn: 0.0 ± 0.0
4.348AspPro: 4.348 ± 0.414
1.449AspGln: 1.449 ± 1.392
2.899AspArg: 2.899 ± 0.489
4.348AspSer: 4.348 ± 0.414
4.348AspThr: 4.348 ± 0.414
1.449AspVal: 1.449 ± 0.903
0.0AspTrp: 0.0 ± 0.0
4.348AspTyr: 4.348 ± 2.709
0.0AspXaa: 0.0 ± 0.0
Glu
1.449GluAla: 1.449 ± 0.903
1.449GluCys: 1.449 ± 0.903
5.797GluAsp: 5.797 ± 3.612
4.348GluGlu: 4.348 ± 2.709
8.696GluPhe: 8.696 ± 5.418
1.449GluGly: 1.449 ± 0.903
0.0GluHis: 0.0 ± 0.0
5.797GluIle: 5.797 ± 1.317
1.449GluLys: 1.449 ± 0.903
1.449GluLeu: 1.449 ± 0.903
0.0GluMet: 0.0 ± 0.0
2.899GluAsn: 2.899 ± 0.489
1.449GluPro: 1.449 ± 0.903
1.449GluGln: 1.449 ± 0.903
5.797GluArg: 5.797 ± 1.317
1.449GluSer: 1.449 ± 0.903
1.449GluThr: 1.449 ± 0.903
1.449GluVal: 1.449 ± 0.903
1.449GluTrp: 1.449 ± 0.903
7.246GluTyr: 7.246 ± 2.22
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.449PheCys: 1.449 ± 1.392
4.348PheAsp: 4.348 ± 2.709
4.348PheGlu: 4.348 ± 0.414
1.449PhePhe: 1.449 ± 0.903
1.449PheGly: 1.449 ± 1.392
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
4.348PheLys: 4.348 ± 2.709
7.246PheLeu: 7.246 ± 2.37
1.449PheMet: 1.449 ± 0.903
1.449PheAsn: 1.449 ± 0.903
1.449PhePro: 1.449 ± 1.392
4.348PheGln: 4.348 ± 0.414
1.449PheArg: 1.449 ± 0.903
1.449PheSer: 1.449 ± 1.392
4.348PheThr: 4.348 ± 0.414
1.449PheVal: 1.449 ± 0.903
0.0PheTrp: 0.0 ± 0.0
1.449PheTyr: 1.449 ± 0.903
0.0PheXaa: 0.0 ± 0.0
Gly
4.348GlyAla: 4.348 ± 0.414
0.0GlyCys: 0.0 ± 0.0
7.246GlyAsp: 7.246 ± 0.075
4.348GlyGlu: 4.348 ± 1.881
2.899GlyPhe: 2.899 ± 1.806
0.0GlyGly: 0.0 ± 0.0
1.449GlyHis: 1.449 ± 0.903
1.449GlyIle: 1.449 ± 1.392
8.696GlyLys: 8.696 ± 3.123
4.348GlyLeu: 4.348 ± 4.176
1.449GlyMet: 1.449 ± 0.903
4.348GlyAsn: 4.348 ± 4.176
2.899GlyPro: 2.899 ± 0.489
2.899GlyGln: 2.899 ± 2.784
0.0GlyArg: 0.0 ± 0.0
0.0GlySer: 0.0 ± 0.0
2.899GlyThr: 2.899 ± 2.784
2.899GlyVal: 2.899 ± 0.489
1.449GlyTrp: 1.449 ± 0.903
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.449HisAla: 1.449 ± 0.903
1.449HisCys: 1.449 ± 0.903
1.449HisAsp: 1.449 ± 0.903
0.0HisGlu: 0.0 ± 0.0
1.449HisPhe: 1.449 ± 0.903
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.449HisLys: 1.449 ± 0.903
1.449HisLeu: 1.449 ± 0.903
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.899HisPro: 2.899 ± 1.806
0.0HisGln: 0.0 ± 0.0
1.449HisArg: 1.449 ± 0.903
1.449HisSer: 1.449 ± 0.903
0.0HisThr: 0.0 ± 0.0
2.899HisVal: 2.899 ± 1.806
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.899IleAla: 2.899 ± 0.489
0.0IleCys: 0.0 ± 0.0
1.449IleAsp: 1.449 ± 1.392
4.348IleGlu: 4.348 ± 2.709
1.449IlePhe: 1.449 ± 0.903
4.348IleGly: 4.348 ± 1.881
0.0IleHis: 0.0 ± 0.0
1.449IleIle: 1.449 ± 0.903
8.696IleLys: 8.696 ± 1.467
2.899IleLeu: 2.899 ± 1.806
0.0IleMet: 0.0 ± 0.0
4.348IleAsn: 4.348 ± 4.176
1.449IlePro: 1.449 ± 0.903
1.449IleGln: 1.449 ± 1.392
0.0IleArg: 0.0 ± 0.0
1.449IleSer: 1.449 ± 1.392
4.348IleThr: 4.348 ± 0.414
1.449IleVal: 1.449 ± 1.392
0.0IleTrp: 0.0 ± 0.0
2.899IleTyr: 2.899 ± 1.806
0.0IleXaa: 0.0 ± 0.0
Lys
7.246LysAla: 7.246 ± 2.22
5.797LysCys: 5.797 ± 0.978
1.449LysAsp: 1.449 ± 0.903
4.348LysGlu: 4.348 ± 2.709
1.449LysPhe: 1.449 ± 0.903
5.797LysGly: 5.797 ± 1.317
1.449LysHis: 1.449 ± 0.903
7.246LysIle: 7.246 ± 0.075
8.696LysLys: 8.696 ± 5.418
4.348LysLeu: 4.348 ± 0.414
0.0LysMet: 0.0 ± 0.0
2.899LysAsn: 2.899 ± 1.806
1.449LysPro: 1.449 ± 0.903
4.348LysGln: 4.348 ± 2.709
5.797LysArg: 5.797 ± 1.317
8.696LysSer: 8.696 ± 3.761
4.348LysThr: 4.348 ± 0.414
4.348LysVal: 4.348 ± 0.414
4.348LysTrp: 4.348 ± 2.709
4.348LysTyr: 4.348 ± 2.709
0.0LysXaa: 0.0 ± 0.0
Leu
4.348LeuAla: 4.348 ± 1.881
1.449LeuCys: 1.449 ± 1.392
8.696LeuAsp: 8.696 ± 0.828
2.899LeuGlu: 2.899 ± 1.806
4.348LeuPhe: 4.348 ± 1.881
2.899LeuGly: 2.899 ± 0.489
1.449LeuHis: 1.449 ± 0.903
2.899LeuIle: 2.899 ± 0.489
8.696LeuLys: 8.696 ± 3.123
4.348LeuLeu: 4.348 ± 1.881
2.899LeuMet: 2.899 ± 0.489
5.797LeuAsn: 5.797 ± 5.567
4.348LeuPro: 4.348 ± 1.881
1.449LeuGln: 1.449 ± 0.903
4.348LeuArg: 4.348 ± 4.176
2.899LeuSer: 2.899 ± 1.806
5.797LeuThr: 5.797 ± 3.612
5.797LeuVal: 5.797 ± 1.317
2.899LeuTrp: 2.899 ± 0.489
1.449LeuTyr: 1.449 ± 1.392
0.0LeuXaa: 0.0 ± 0.0
Met
2.899MetAla: 2.899 ± 1.806
0.0MetCys: 0.0 ± 0.0
2.899MetAsp: 2.899 ± 0.489
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.449MetIle: 1.449 ± 0.903
2.899MetLys: 2.899 ± 1.806
2.899MetLeu: 2.899 ± 0.489
2.899MetMet: 2.899 ± 1.806
0.0MetAsn: 0.0 ± 0.0
2.899MetPro: 2.899 ± 0.489
1.449MetGln: 1.449 ± 0.903
2.899MetArg: 2.899 ± 0.489
1.449MetSer: 1.449 ± 1.392
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.797AsnAla: 5.797 ± 5.567
0.0AsnCys: 0.0 ± 0.0
4.348AsnAsp: 4.348 ± 0.414
1.449AsnGlu: 1.449 ± 0.903
4.348AsnPhe: 4.348 ± 1.881
8.696AsnGly: 8.696 ± 3.761
1.449AsnHis: 1.449 ± 0.903
1.449AsnIle: 1.449 ± 1.392
4.348AsnLys: 4.348 ± 0.414
5.797AsnLeu: 5.797 ± 3.273
0.0AsnMet: 0.0 ± 0.0
1.449AsnAsn: 1.449 ± 1.392
2.899AsnPro: 2.899 ± 2.784
1.449AsnGln: 1.449 ± 1.392
1.449AsnArg: 1.449 ± 1.392
5.797AsnSer: 5.797 ± 0.978
1.449AsnThr: 1.449 ± 0.903
4.348AsnVal: 4.348 ± 0.414
1.449AsnTrp: 1.449 ± 0.903
1.449AsnTyr: 1.449 ± 0.903
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.449ProAsp: 1.449 ± 1.392
1.449ProGlu: 1.449 ± 0.903
1.449ProPhe: 1.449 ± 0.903
1.449ProGly: 1.449 ± 0.903
1.449ProHis: 1.449 ± 0.903
1.449ProIle: 1.449 ± 0.903
2.899ProLys: 2.899 ± 1.806
1.449ProLeu: 1.449 ± 0.903
4.348ProMet: 4.348 ± 1.881
5.797ProAsn: 5.797 ± 0.978
2.899ProPro: 2.899 ± 1.806
4.348ProGln: 4.348 ± 0.414
4.348ProArg: 4.348 ± 1.881
5.797ProSer: 5.797 ± 5.567
5.797ProThr: 5.797 ± 3.273
7.246ProVal: 7.246 ± 2.22
2.899ProTrp: 2.899 ± 0.489
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
7.246GlnAla: 7.246 ± 2.37
1.449GlnCys: 1.449 ± 0.903
0.0GlnAsp: 0.0 ± 0.0
1.449GlnGlu: 1.449 ± 0.903
0.0GlnPhe: 0.0 ± 0.0
2.899GlnGly: 2.899 ± 0.489
1.449GlnHis: 1.449 ± 0.903
0.0GlnIle: 0.0 ± 0.0
2.899GlnLys: 2.899 ± 0.489
1.449GlnLeu: 1.449 ± 0.903
1.449GlnMet: 1.449 ± 0.903
1.449GlnAsn: 1.449 ± 1.392
2.899GlnPro: 2.899 ± 0.489
2.899GlnGln: 2.899 ± 0.489
4.348GlnArg: 4.348 ± 1.881
2.899GlnSer: 2.899 ± 0.489
1.449GlnThr: 1.449 ± 1.392
1.449GlnVal: 1.449 ± 1.392
1.449GlnTrp: 1.449 ± 0.903
1.449GlnTyr: 1.449 ± 0.903
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
1.449ArgAsp: 1.449 ± 0.903
1.449ArgGlu: 1.449 ± 0.903
4.348ArgPhe: 4.348 ± 1.881
1.449ArgGly: 1.449 ± 1.392
1.449ArgHis: 1.449 ± 0.903
1.449ArgIle: 1.449 ± 1.392
2.899ArgLys: 2.899 ± 0.489
2.899ArgLeu: 2.899 ± 2.784
0.0ArgMet: 0.0 ± 0.0
4.348ArgAsn: 4.348 ± 0.414
1.449ArgPro: 1.449 ± 1.392
2.899ArgGln: 2.899 ± 0.489
2.899ArgArg: 2.899 ± 0.489
4.348ArgSer: 4.348 ± 0.414
7.246ArgThr: 7.246 ± 0.075
4.348ArgVal: 4.348 ± 1.881
1.449ArgTrp: 1.449 ± 0.903
4.348ArgTyr: 4.348 ± 1.881
0.0ArgXaa: 0.0 ± 0.0
Ser
1.449SerAla: 1.449 ± 1.392
0.0SerCys: 0.0 ± 0.0
1.449SerAsp: 1.449 ± 0.903
4.348SerGlu: 4.348 ± 2.709
1.449SerPhe: 1.449 ± 0.903
1.449SerGly: 1.449 ± 1.392
0.0SerHis: 0.0 ± 0.0
4.348SerIle: 4.348 ± 1.881
4.348SerLys: 4.348 ± 0.414
7.246SerLeu: 7.246 ± 0.075
0.0SerMet: 0.0 ± 0.0
7.246SerAsn: 7.246 ± 4.664
2.899SerPro: 2.899 ± 2.784
7.246SerGln: 7.246 ± 4.664
0.0SerArg: 0.0 ± 0.0
7.246SerSer: 7.246 ± 2.37
1.449SerThr: 1.449 ± 0.903
4.348SerVal: 4.348 ± 1.881
1.449SerTrp: 1.449 ± 1.392
4.348SerTyr: 4.348 ± 1.881
0.0SerXaa: 0.0 ± 0.0
Thr
1.449ThrAla: 1.449 ± 1.392
0.0ThrCys: 0.0 ± 0.0
4.348ThrAsp: 4.348 ± 0.414
2.899ThrGlu: 2.899 ± 1.806
1.449ThrPhe: 1.449 ± 1.392
4.348ThrGly: 4.348 ± 4.176
1.449ThrHis: 1.449 ± 0.903
1.449ThrIle: 1.449 ± 0.903
2.899ThrLys: 2.899 ± 0.489
10.145ThrLeu: 10.145 ± 1.731
0.0ThrMet: 0.0 ± 0.0
1.449ThrAsn: 1.449 ± 1.392
1.449ThrPro: 1.449 ± 0.903
0.0ThrGln: 0.0 ± 0.0
2.899ThrArg: 2.899 ± 0.489
2.899ThrSer: 2.899 ± 0.489
7.246ThrThr: 7.246 ± 0.075
5.797ThrVal: 5.797 ± 0.978
1.449ThrTrp: 1.449 ± 1.392
5.797ThrTyr: 5.797 ± 0.978
0.0ThrXaa: 0.0 ± 0.0
Val
2.899ValAla: 2.899 ± 0.489
1.449ValCys: 1.449 ± 0.903
2.899ValAsp: 2.899 ± 1.806
2.899ValGlu: 2.899 ± 1.806
0.0ValPhe: 0.0 ± 0.0
4.348ValGly: 4.348 ± 4.176
1.449ValHis: 1.449 ± 0.903
1.449ValIle: 1.449 ± 1.392
5.797ValLys: 5.797 ± 3.612
5.797ValLeu: 5.797 ± 0.978
2.899ValMet: 2.899 ± 0.489
2.899ValAsn: 2.899 ± 1.806
8.696ValPro: 8.696 ± 0.828
0.0ValGln: 0.0 ± 0.0
5.797ValArg: 5.797 ± 0.978
1.449ValSer: 1.449 ± 1.392
2.899ValThr: 2.899 ± 2.784
4.348ValVal: 4.348 ± 2.709
1.449ValTrp: 1.449 ± 0.903
1.449ValTyr: 1.449 ± 1.392
0.0ValXaa: 0.0 ± 0.0
Trp
4.348TrpAla: 4.348 ± 2.709
0.0TrpCys: 0.0 ± 0.0
1.449TrpAsp: 1.449 ± 0.903
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.449TrpGly: 1.449 ± 0.903
0.0TrpHis: 0.0 ± 0.0
1.449TrpIle: 1.449 ± 1.392
0.0TrpLys: 0.0 ± 0.0
1.449TrpLeu: 1.449 ± 0.903
1.449TrpMet: 1.449 ± 0.903
1.449TrpAsn: 1.449 ± 0.903
1.449TrpPro: 1.449 ± 0.903
1.449TrpGln: 1.449 ± 0.903
0.0TrpArg: 0.0 ± 0.0
2.899TrpSer: 2.899 ± 0.489
0.0TrpThr: 0.0 ± 0.0
4.348TrpVal: 4.348 ± 1.881
1.449TrpTrp: 1.449 ± 1.392
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.449TyrAla: 1.449 ± 1.392
1.449TyrCys: 1.449 ± 0.903
2.899TyrAsp: 2.899 ± 2.784
2.899TyrGlu: 2.899 ± 1.806
2.899TyrPhe: 2.899 ± 1.806
4.348TyrGly: 4.348 ± 2.709
1.449TyrHis: 1.449 ± 0.903
4.348TyrIle: 4.348 ± 0.414
5.797TyrLys: 5.797 ± 0.978
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
4.348TyrAsn: 4.348 ± 0.414
2.899TyrPro: 2.899 ± 0.489
1.449TyrGln: 1.449 ± 0.903
2.899TyrArg: 2.899 ± 0.489
1.449TyrSer: 1.449 ± 0.903
0.0TyrThr: 0.0 ± 0.0
0.0TyrVal: 0.0 ± 0.0
1.449TyrTrp: 1.449 ± 0.903
1.449TyrTyr: 1.449 ± 1.392
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (691 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski