Amino acid dipepetide frequency for Cladophialophora yegresii CBS 114405

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.452AlaAla: 9.452 ± 0.06	1.035AlaCys: 1.035 ± 0.015	4.558AlaAsp: 4.558 ± 0.034	5.481AlaGlu: 5.481 ± 0.046	3.192AlaPhe: 3.192 ± 0.029	6.207AlaGly: 6.207 ± 0.04	1.897AlaHis: 1.897 ± 0.018	4.22AlaIle: 4.22 ± 0.032	4.251AlaLys: 4.251 ± 0.04	7.873AlaLeu: 7.873 ± 0.049	2.0AlaMet: 2.0 ± 0.025	2.986AlaAsn: 2.986 ± 0.024	4.884AlaPro: 4.884 ± 0.049	3.821AlaGln: 3.821 ± 0.034	5.384AlaArg: 5.384 ± 0.033	7.36AlaSer: 7.36 ± 0.043	5.668AlaThr: 5.668 ± 0.037	5.627AlaVal: 5.627 ± 0.041	1.193AlaTrp: 1.193 ± 0.016	2.204AlaTyr: 2.204 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.93CysAla: 0.93 ± 0.014	0.218CysCys: 0.218 ± 0.008	0.614CysAsp: 0.614 ± 0.012	0.55CysGlu: 0.55 ± 0.011	0.514CysPhe: 0.514 ± 0.01	0.865CysGly: 0.865 ± 0.016	0.32CysHis: 0.32 ± 0.009	0.627CysIle: 0.627 ± 0.011	0.469CysLys: 0.469 ± 0.009	1.214CysLeu: 1.214 ± 0.016	0.254CysMet: 0.254 ± 0.009	0.377CysAsn: 0.377 ± 0.009	0.623CysPro: 0.623 ± 0.013	0.43CysGln: 0.43 ± 0.011	0.71CysArg: 0.71 ± 0.014	0.795CysSer: 0.795 ± 0.014	0.627CysThr: 0.627 ± 0.012	0.761CysVal: 0.761 ± 0.012	0.19CysTrp: 0.19 ± 0.006	0.348CysTyr: 0.348 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.937AspAla: 4.937 ± 0.036	0.595AspCys: 0.595 ± 0.011	4.34AspAsp: 4.34 ± 0.045	4.643AspGlu: 4.643 ± 0.04	2.266AspPhe: 2.266 ± 0.026	4.114AspGly: 4.114 ± 0.033	1.328AspHis: 1.328 ± 0.019	2.881AspIle: 2.881 ± 0.024	2.409AspLys: 2.409 ± 0.023	5.193AspLeu: 5.193 ± 0.035	1.272AspMet: 1.272 ± 0.017	1.801AspAsn: 1.801 ± 0.021	3.447AspPro: 3.447 ± 0.026	2.011AspGln: 2.011 ± 0.022	3.196AspArg: 3.196 ± 0.031	3.959AspSer: 3.959 ± 0.029	3.055AspThr: 3.055 ± 0.026	3.917AspVal: 3.917 ± 0.028	0.889AspTrp: 0.889 ± 0.016	1.55AspTyr: 1.55 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.614GluAla: 5.614 ± 0.045	0.564GluCys: 0.564 ± 0.012	4.372GluAsp: 4.372 ± 0.045	5.323GluGlu: 5.323 ± 0.049	1.867GluPhe: 1.867 ± 0.021	3.844GluGly: 3.844 ± 0.032	1.488GluHis: 1.488 ± 0.017	2.918GluIle: 2.918 ± 0.027	3.68GluLys: 3.68 ± 0.034	5.117GluLeu: 5.117 ± 0.044	1.474GluMet: 1.474 ± 0.02	2.099GluAsn: 2.099 ± 0.021	2.783GluPro: 2.783 ± 0.038	2.691GluGln: 2.691 ± 0.028	4.028GluArg: 4.028 ± 0.034	4.057GluSer: 4.057 ± 0.03	3.368GluThr: 3.368 ± 0.026	3.718GluVal: 3.718 ± 0.032	0.87GluTrp: 0.87 ± 0.013	1.606GluTyr: 1.606 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.121PheAla: 3.121 ± 0.027	0.53PheCys: 0.53 ± 0.011	2.328PheAsp: 2.328 ± 0.022	2.157PheGlu: 2.157 ± 0.021	1.559PhePhe: 1.559 ± 0.022	2.866PheGly: 2.866 ± 0.031	0.888PheHis: 0.888 ± 0.013	1.654PheIle: 1.654 ± 0.024	1.43PheLys: 1.43 ± 0.017	3.434PheLeu: 3.434 ± 0.035	0.769PheMet: 0.769 ± 0.014	1.359PheAsn: 1.359 ± 0.017	1.912PhePro: 1.912 ± 0.02	1.37PheGln: 1.37 ± 0.02	1.965PheArg: 1.965 ± 0.02	2.827PheSer: 2.827 ± 0.024	2.062PheThr: 2.062 ± 0.02	2.441PheVal: 2.441 ± 0.026	0.632PheTrp: 0.632 ± 0.012	1.069PheTyr: 1.069 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.498GlyAla: 5.498 ± 0.045	0.796GlyCys: 0.796 ± 0.015	3.675GlyAsp: 3.675 ± 0.03	3.687GlyGlu: 3.687 ± 0.03	2.812GlyPhe: 2.812 ± 0.024	5.976GlyGly: 5.976 ± 0.058	1.785GlyHis: 1.785 ± 0.021	3.4GlyIle: 3.4 ± 0.035	3.453GlyLys: 3.453 ± 0.029	6.161GlyLeu: 6.161 ± 0.041	1.695GlyMet: 1.695 ± 0.022	2.42GlyAsn: 2.42 ± 0.026	3.481GlyPro: 3.481 ± 0.031	2.713GlyGln: 2.713 ± 0.026	4.341GlyArg: 4.341 ± 0.035	5.559GlySer: 5.559 ± 0.041	4.155GlyThr: 4.155 ± 0.03	4.514GlyVal: 4.514 ± 0.037	1.155GlyTrp: 1.155 ± 0.015	2.13GlyTyr: 2.13 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	2.043HisAla: 2.043 ± 0.019	0.31HisCys: 0.31 ± 0.01	1.435HisAsp: 1.435 ± 0.018	1.435HisGlu: 1.435 ± 0.016	0.952HisPhe: 0.952 ± 0.013	1.819HisGly: 1.819 ± 0.023	0.862HisHis: 0.862 ± 0.016	1.183HisIle: 1.183 ± 0.017	0.963HisLys: 0.963 ± 0.014	2.266HisLeu: 2.266 ± 0.022	0.503HisMet: 0.503 ± 0.012	0.847HisAsn: 0.847 ± 0.014	1.685HisPro: 1.685 ± 0.018	1.027HisGln: 1.027 ± 0.015	1.555HisArg: 1.555 ± 0.019	1.826HisSer: 1.826 ± 0.022	1.282HisThr: 1.282 ± 0.019	1.565HisVal: 1.565 ± 0.022	0.342HisTrp: 0.342 ± 0.009	0.677HisTyr: 0.677 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.134IleAla: 4.134 ± 0.033	0.708IleCys: 0.708 ± 0.013	2.78IleAsp: 2.78 ± 0.025	2.699IleGlu: 2.699 ± 0.027	1.861IlePhe: 1.861 ± 0.024	3.059IleGly: 3.059 ± 0.03	1.152IleHis: 1.152 ± 0.016	2.286IleIle: 2.286 ± 0.026	2.055IleLys: 2.055 ± 0.022	4.412IleLeu: 4.412 ± 0.037	0.945IleMet: 0.945 ± 0.016	1.693IleAsn: 1.693 ± 0.019	2.946IlePro: 2.946 ± 0.028	1.828IleGln: 1.828 ± 0.019	2.706IleArg: 2.706 ± 0.021	3.604IleSer: 3.604 ± 0.029	2.704IleThr: 2.704 ± 0.026	3.092IleVal: 3.092 ± 0.026	0.71IleTrp: 0.71 ± 0.014	1.335IleTyr: 1.335 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.335LysAla: 4.335 ± 0.037	0.475LysCys: 0.475 ± 0.011	2.882LysAsp: 2.882 ± 0.027	3.304LysGlu: 3.304 ± 0.036	1.444LysPhe: 1.444 ± 0.019	2.958LysGly: 2.958 ± 0.032	1.204LysHis: 1.204 ± 0.015	2.229LysIle: 2.229 ± 0.026	3.215LysLys: 3.215 ± 0.052	3.987LysLeu: 3.987 ± 0.033	1.005LysMet: 1.005 ± 0.015	1.631LysAsn: 1.631 ± 0.02	2.751LysPro: 2.751 ± 0.029	1.965LysGln: 1.965 ± 0.02	3.473LysArg: 3.473 ± 0.031	3.424LysSer: 3.424 ± 0.032	2.762LysThr: 2.762 ± 0.025	2.866LysVal: 2.866 ± 0.03	0.68LysTrp: 0.68 ± 0.012	1.359LysTyr: 1.359 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	8.11LeuAla: 8.11 ± 0.049	1.192LeuCys: 1.192 ± 0.018	5.203LeuAsp: 5.203 ± 0.035	5.483LeuGlu: 5.483 ± 0.043	3.243LeuPhe: 3.243 ± 0.029	5.971LeuGly: 5.971 ± 0.044	2.228LeuHis: 2.228 ± 0.025	3.74LeuIle: 3.74 ± 0.032	4.235LeuLys: 4.235 ± 0.032	8.212LeuLeu: 8.212 ± 0.064	1.784LeuMet: 1.784 ± 0.021	3.1LeuAsn: 3.1 ± 0.025	5.502LeuPro: 5.502 ± 0.04	3.869LeuGln: 3.869 ± 0.033	5.841LeuArg: 5.841 ± 0.039	7.03LeuSer: 7.03 ± 0.043	4.858LeuThr: 4.858 ± 0.034	5.474LeuVal: 5.474 ± 0.039	1.189LeuTrp: 1.189 ± 0.019	2.322LeuTyr: 2.322 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.283MetAla: 2.283 ± 0.023	0.249MetCys: 0.249 ± 0.007	1.223MetAsp: 1.223 ± 0.018	1.174MetGlu: 1.174 ± 0.016	0.746MetPhe: 0.746 ± 0.014	1.456MetGly: 1.456 ± 0.017	0.504MetHis: 0.504 ± 0.01	0.951MetIle: 0.951 ± 0.014	0.961MetLys: 0.961 ± 0.016	1.898MetLeu: 1.898 ± 0.02	0.541MetMet: 0.541 ± 0.011	0.778MetAsn: 0.778 ± 0.013	1.329MetPro: 1.329 ± 0.018	0.9MetGln: 0.9 ± 0.017	1.256MetArg: 1.256 ± 0.016	1.857MetSer: 1.857 ± 0.021	1.31MetThr: 1.31 ± 0.017	1.304MetVal: 1.304 ± 0.017	0.255MetTrp: 0.255 ± 0.008	0.535MetTyr: 0.535 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.247AsnAla: 3.247 ± 0.027	0.384AsnCys: 0.384 ± 0.01	1.92AsnAsp: 1.92 ± 0.025	1.957AsnGlu: 1.957 ± 0.022	1.298AsnPhe: 1.298 ± 0.016	2.978AsnGly: 2.978 ± 0.033	0.869AsnHis: 0.869 ± 0.013	1.882AsnIle: 1.882 ± 0.021	1.488AsnLys: 1.488 ± 0.019	3.141AsnLeu: 3.141 ± 0.027	0.763AsnMet: 0.763 ± 0.014	1.354AsnAsn: 1.354 ± 0.02	2.363AsnPro: 2.363 ± 0.021	1.289AsnGln: 1.289 ± 0.018	1.858AsnArg: 1.858 ± 0.021	2.486AsnSer: 2.486 ± 0.024	2.113AsnThr: 2.113 ± 0.02	2.342AsnVal: 2.342 ± 0.022	0.518AsnTrp: 0.518 ± 0.01	0.985AsnTyr: 0.985 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.551ProAla: 5.551 ± 0.046	0.467ProCys: 0.467 ± 0.01	3.297ProAsp: 3.297 ± 0.026	3.825ProGlu: 3.825 ± 0.032	2.05ProPhe: 2.05 ± 0.022	4.079ProGly: 4.079 ± 0.033	1.355ProHis: 1.355 ± 0.019	2.427ProIle: 2.427 ± 0.024	2.625ProLys: 2.625 ± 0.025	4.795ProLeu: 4.795 ± 0.033	1.084ProMet: 1.084 ± 0.019	2.142ProAsn: 2.142 ± 0.022	5.36ProPro: 5.36 ± 0.074	2.68ProGln: 2.68 ± 0.031	3.579ProArg: 3.579 ± 0.033	5.961ProSer: 5.961 ± 0.056	4.133ProThr: 4.133 ± 0.035	3.679ProVal: 3.679 ± 0.034	0.719ProTrp: 0.719 ± 0.012	1.527ProTyr: 1.527 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.781GlnAla: 3.781 ± 0.032	0.412GlnCys: 0.412 ± 0.009	2.199GlnAsp: 2.199 ± 0.024	2.522GlnGlu: 2.522 ± 0.027	1.306GlnPhe: 1.306 ± 0.016	2.555GlnGly: 2.555 ± 0.025	1.193GlnHis: 1.193 ± 0.017	1.915GlnIle: 1.915 ± 0.019	2.09GlnLys: 2.09 ± 0.026	3.496GlnLeu: 3.496 ± 0.029	0.915GlnMet: 0.915 ± 0.017	1.558GlnAsn: 1.558 ± 0.02	2.745GlnPro: 2.745 ± 0.036	2.556GlnGln: 2.556 ± 0.043	2.803GlnArg: 2.803 ± 0.027	3.255GlnSer: 3.255 ± 0.032	2.401GlnThr: 2.401 ± 0.025	2.244GlnVal: 2.244 ± 0.024	0.572GlnTrp: 0.572 ± 0.01	1.208GlnTyr: 1.208 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.026ArgAla: 5.026 ± 0.04	0.649ArgCys: 0.649 ± 0.012	3.537ArgAsp: 3.537 ± 0.031	3.888ArgGlu: 3.888 ± 0.033	2.051ArgPhe: 2.051 ± 0.02	3.839ArgGly: 3.839 ± 0.03	1.691ArgHis: 1.691 ± 0.022	2.777ArgIle: 2.777 ± 0.021	3.61ArgLys: 3.61 ± 0.033	5.585ArgLeu: 5.585 ± 0.043	1.345ArgMet: 1.345 ± 0.018	2.251ArgAsn: 2.251 ± 0.02	3.774ArgPro: 3.774 ± 0.035	2.853ArgGln: 2.853 ± 0.028	5.364ArgArg: 5.364 ± 0.046	4.825ArgSer: 4.825 ± 0.04	3.486ArgThr: 3.486 ± 0.03	3.416ArgVal: 3.416 ± 0.029	0.937ArgTrp: 0.937 ± 0.015	1.68ArgTyr: 1.68 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.779SerAla: 6.779 ± 0.039	0.786SerCys: 0.786 ± 0.014	4.101SerAsp: 4.101 ± 0.03	4.03SerGlu: 4.03 ± 0.033	2.831SerPhe: 2.831 ± 0.024	5.43SerGly: 5.43 ± 0.038	1.922SerHis: 1.922 ± 0.019	3.743SerIle: 3.743 ± 0.031	3.572SerLys: 3.572 ± 0.035	6.91SerLeu: 6.91 ± 0.047	1.7SerMet: 1.7 ± 0.019	2.829SerAsn: 2.829 ± 0.027	5.58SerPro: 5.58 ± 0.052	3.31SerGln: 3.31 ± 0.027	5.065SerArg: 5.065 ± 0.039	8.311SerSer: 8.311 ± 0.065	5.679SerThr: 5.679 ± 0.048	4.483SerVal: 4.483 ± 0.031	1.079SerTrp: 1.079 ± 0.018	1.959SerTyr: 1.959 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.544ThrAla: 5.544 ± 0.04	0.68ThrCys: 0.68 ± 0.013	2.958ThrAsp: 2.958 ± 0.028	3.078ThrGlu: 3.078 ± 0.028	2.246ThrPhe: 2.246 ± 0.021	4.267ThrGly: 4.267 ± 0.036	1.299ThrHis: 1.299 ± 0.018	3.003ThrIle: 3.003 ± 0.026	2.641ThrLys: 2.641 ± 0.027	5.199ThrLeu: 5.199 ± 0.038	1.195ThrMet: 1.195 ± 0.015	2.155ThrAsn: 2.155 ± 0.025	4.376ThrPro: 4.376 ± 0.038	2.19ThrGln: 2.19 ± 0.022	3.259ThrArg: 3.259 ± 0.025	5.47ThrSer: 5.47 ± 0.043	4.526ThrThr: 4.526 ± 0.049	3.781ThrVal: 3.781 ± 0.03	0.845ThrTrp: 0.845 ± 0.016	1.597ThrTyr: 1.597 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	5.574ValAla: 5.574 ± 0.036	0.81ValCys: 0.81 ± 0.013	3.878ValAsp: 3.878 ± 0.03	3.948ValGlu: 3.948 ± 0.03	2.412ValPhe: 2.412 ± 0.025	4.164ValGly: 4.164 ± 0.034	1.453ValHis: 1.453 ± 0.016	2.814ValIle: 2.814 ± 0.026	2.965ValLys: 2.965 ± 0.031	5.678ValLeu: 5.678 ± 0.037	1.316ValMet: 1.316 ± 0.019	2.196ValAsn: 2.196 ± 0.023	3.714ValPro: 3.714 ± 0.033	2.509ValGln: 2.509 ± 0.026	3.613ValArg: 3.613 ± 0.027	4.551ValSer: 4.551 ± 0.027	3.571ValThr: 3.571 ± 0.031	4.492ValVal: 4.492 ± 0.034	0.863ValTrp: 0.863 ± 0.014	1.667ValTyr: 1.667 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.106TrpAla: 1.106 ± 0.016	0.191TrpCys: 0.191 ± 0.006	0.859TrpAsp: 0.859 ± 0.014	0.802TrpGlu: 0.802 ± 0.014	0.531TrpPhe: 0.531 ± 0.011	0.877TrpGly: 0.877 ± 0.014	0.375TrpHis: 0.375 ± 0.01	0.749TrpIle: 0.749 ± 0.014	0.765TrpLys: 0.765 ± 0.014	1.373TrpLeu: 1.373 ± 0.019	0.363TrpMet: 0.363 ± 0.01	0.571TrpAsn: 0.571 ± 0.011	0.603TrpPro: 0.603 ± 0.012	0.597TrpGln: 0.597 ± 0.011	0.998TrpArg: 0.998 ± 0.015	1.052TrpSer: 1.052 ± 0.014	0.959TrpThr: 0.959 ± 0.015	0.856TrpVal: 0.856 ± 0.012	0.272TrpTrp: 0.272 ± 0.008	0.44TrpTyr: 0.44 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.23TyrAla: 2.23 ± 0.021	0.385TyrCys: 0.385 ± 0.009	1.642TyrAsp: 1.642 ± 0.019	1.495TyrGlu: 1.495 ± 0.018	1.191TyrPhe: 1.191 ± 0.016	2.084TyrGly: 2.084 ± 0.024	0.763TyrHis: 0.763 ± 0.013	1.308TyrIle: 1.308 ± 0.016	1.075TyrLys: 1.075 ± 0.016	2.641TyrLeu: 2.641 ± 0.026	0.589TyrMet: 0.589 ± 0.012	1.087TyrAsn: 1.087 ± 0.016	1.475TyrPro: 1.475 ± 0.02	1.117TyrGln: 1.117 ± 0.016	1.59TyrArg: 1.59 ± 0.017	1.892TyrSer: 1.892 ± 0.018	1.593TyrThr: 1.593 ± 0.018	1.613TyrVal: 1.613 ± 0.018	0.429TyrTrp: 0.429 ± 0.01	0.863TyrTyr: 0.863 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10118 proteins (4906581 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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