Amino acid dipepetide frequency for Persimmon virus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.141AlaAla: 3.141 ± 1.581
0.262AlaCys: 0.262 ± 0.153
3.141AlaAsp: 3.141 ± 0.873
2.094AlaGlu: 2.094 ± 1.168
1.309AlaPhe: 1.309 ± 1.101
2.618AlaGly: 2.618 ± 0.575
0.524AlaHis: 0.524 ± 0.656
3.141AlaIle: 3.141 ± 0.515
2.094AlaLys: 2.094 ± 0.881
3.927AlaLeu: 3.927 ± 0.815
2.88AlaMet: 2.88 ± 0.706
2.094AlaAsn: 2.094 ± 0.604
1.571AlaPro: 1.571 ± 1.167
0.524AlaGln: 0.524 ± 0.289
2.88AlaArg: 2.88 ± 0.712
5.759AlaSer: 5.759 ± 1.221
3.141AlaThr: 3.141 ± 0.97
3.665AlaVal: 3.665 ± 1.446
0.262AlaTrp: 0.262 ± 0.153
2.094AlaTyr: 2.094 ± 0.478
0.0AlaXaa: 0.0 ± 0.0
Cys
1.309CysAla: 1.309 ± 0.548
0.262CysCys: 0.262 ± 0.153
0.785CysAsp: 0.785 ± 0.722
1.571CysGlu: 1.571 ± 0.6
1.309CysPhe: 1.309 ± 0.314
1.571CysGly: 1.571 ± 1.131
0.0CysHis: 0.0 ± 0.0
0.785CysIle: 0.785 ± 0.26
1.309CysLys: 1.309 ± 1.215
1.571CysLeu: 1.571 ± 0.689
1.309CysMet: 1.309 ± 0.767
1.047CysAsn: 1.047 ± 0.33
0.785CysPro: 0.785 ± 0.533
0.262CysGln: 0.262 ± 0.328
0.524CysArg: 0.524 ± 0.253
2.094CysSer: 2.094 ± 0.604
1.309CysThr: 1.309 ± 0.446
1.047CysVal: 1.047 ± 0.458
0.262CysTrp: 0.262 ± 0.313
0.785CysTyr: 0.785 ± 0.46
0.0CysXaa: 0.0 ± 0.0
Asp
2.618AspAla: 2.618 ± 0.406
0.785AspCys: 0.785 ± 0.46
4.45AspAsp: 4.45 ± 1.201
3.665AspGlu: 3.665 ± 0.862
1.047AspPhe: 1.047 ± 0.497
3.403AspGly: 3.403 ± 0.753
2.094AspHis: 2.094 ± 0.552
3.927AspIle: 3.927 ± 0.96
4.45AspLys: 4.45 ± 1.651
8.377AspLeu: 8.377 ± 1.483
2.618AspMet: 2.618 ± 1.024
2.094AspAsn: 2.094 ± 0.704
2.618AspPro: 2.618 ± 0.736
2.094AspGln: 2.094 ± 0.616
2.618AspArg: 2.618 ± 0.871
3.665AspSer: 3.665 ± 0.736
3.141AspThr: 3.141 ± 0.465
3.927AspVal: 3.927 ± 0.968
1.571AspTrp: 1.571 ± 0.46
3.665AspTyr: 3.665 ± 0.996
0.0AspXaa: 0.0 ± 0.0
Glu
3.141GluAla: 3.141 ± 0.792
1.832GluCys: 1.832 ± 1.453
4.45GluAsp: 4.45 ± 0.949
4.712GluGlu: 4.712 ± 1.885
1.309GluPhe: 1.309 ± 0.715
3.665GluGly: 3.665 ± 0.978
1.047GluHis: 1.047 ± 0.416
3.665GluIle: 3.665 ± 1.35
4.45GluLys: 4.45 ± 0.711
5.759GluLeu: 5.759 ± 0.534
2.618GluMet: 2.618 ± 1.474
3.141GluAsn: 3.141 ± 0.822
2.094GluPro: 2.094 ± 1.158
1.571GluGln: 1.571 ± 0.553
2.618GluArg: 2.618 ± 0.537
6.806GluSer: 6.806 ± 0.785
3.665GluThr: 3.665 ± 1.147
3.403GluVal: 3.403 ± 1.637
1.309GluTrp: 1.309 ± 0.464
1.047GluTyr: 1.047 ± 0.293
0.0GluXaa: 0.0 ± 0.0
Phe
1.832PheAla: 1.832 ± 0.664
1.571PheCys: 1.571 ± 0.657
1.571PheAsp: 1.571 ± 0.673
2.094PheGlu: 2.094 ± 1.232
1.571PhePhe: 1.571 ± 0.398
2.618PheGly: 2.618 ± 1.136
0.524PheHis: 0.524 ± 0.456
1.571PheIle: 1.571 ± 0.563
1.309PheLys: 1.309 ± 0.661
2.094PheLeu: 2.094 ± 0.889
1.047PheMet: 1.047 ± 0.607
1.571PheAsn: 1.571 ± 0.979
1.832PhePro: 1.832 ± 1.01
1.047PheGln: 1.047 ± 0.614
1.309PheArg: 1.309 ± 0.445
4.712PheSer: 4.712 ± 1.849
1.832PheThr: 1.832 ± 0.614
2.094PheVal: 2.094 ± 1.612
0.262PheTrp: 0.262 ± 0.153
0.524PheTyr: 0.524 ± 0.307
0.0PheXaa: 0.0 ± 0.0
Gly
2.356GlyAla: 2.356 ± 0.83
0.524GlyCys: 0.524 ± 0.253
4.188GlyAsp: 4.188 ± 1.053
3.141GlyGlu: 3.141 ± 0.336
2.094GlyPhe: 2.094 ± 1.401
2.094GlyGly: 2.094 ± 0.523
2.094GlyHis: 2.094 ± 0.489
1.832GlyIle: 1.832 ± 0.48
6.806GlyLys: 6.806 ± 1.625
6.806GlyLeu: 6.806 ± 1.269
3.665GlyMet: 3.665 ± 0.948
2.094GlyAsn: 2.094 ± 0.941
0.785GlyPro: 0.785 ± 0.852
1.309GlyGln: 1.309 ± 0.549
0.524GlyArg: 0.524 ± 0.307
3.927GlySer: 3.927 ± 0.986
2.618GlyThr: 2.618 ± 1.04
2.88GlyVal: 2.88 ± 0.649
0.524GlyTrp: 0.524 ± 0.307
1.832GlyTyr: 1.832 ± 0.487
0.0GlyXaa: 0.0 ± 0.0
His
0.785HisAla: 0.785 ± 0.476
0.785HisCys: 0.785 ± 0.872
0.524HisAsp: 0.524 ± 0.253
0.524HisGlu: 0.524 ± 0.456
0.785HisPhe: 0.785 ± 0.46
1.047HisGly: 1.047 ± 0.482
0.785HisHis: 0.785 ± 0.26
1.571HisIle: 1.571 ± 0.757
1.309HisLys: 1.309 ± 0.435
1.832HisLeu: 1.832 ± 0.607
2.094HisMet: 2.094 ± 0.926
1.047HisAsn: 1.047 ± 0.866
1.309HisPro: 1.309 ± 0.568
0.262HisGln: 0.262 ± 0.328
1.309HisArg: 1.309 ± 0.464
0.785HisSer: 0.785 ± 0.522
0.262HisThr: 0.262 ± 0.328
1.309HisVal: 1.309 ± 0.426
0.262HisTrp: 0.262 ± 0.328
0.785HisTyr: 0.785 ± 0.476
0.0HisXaa: 0.0 ± 0.0
Ile
3.665IleAla: 3.665 ± 1.035
1.309IleCys: 1.309 ± 0.767
3.141IleAsp: 3.141 ± 1.784
3.141IleGlu: 3.141 ± 0.957
2.094IlePhe: 2.094 ± 0.649
3.141IleGly: 3.141 ± 0.891
1.047IleHis: 1.047 ± 0.907
3.403IleIle: 3.403 ± 0.798
4.712IleLys: 4.712 ± 0.813
5.497IleLeu: 5.497 ± 0.678
2.356IleMet: 2.356 ± 0.786
4.712IleAsn: 4.712 ± 1.449
2.88IlePro: 2.88 ± 0.667
2.094IleGln: 2.094 ± 0.534
4.712IleArg: 4.712 ± 1.055
4.712IleSer: 4.712 ± 0.722
5.236IleThr: 5.236 ± 1.57
3.927IleVal: 3.927 ± 0.633
0.524IleTrp: 0.524 ± 0.253
3.141IleTyr: 3.141 ± 0.735
0.0IleXaa: 0.0 ± 0.0
Lys
2.356LysAla: 2.356 ± 0.918
1.309LysCys: 1.309 ± 0.789
5.236LysAsp: 5.236 ± 0.938
6.283LysGlu: 6.283 ± 1.33
2.094LysPhe: 2.094 ± 0.614
4.45LysGly: 4.45 ± 0.439
1.047LysHis: 1.047 ± 0.461
6.806LysIle: 6.806 ± 1.509
7.33LysLys: 7.33 ± 1.732
6.806LysLeu: 6.806 ± 1.624
1.832LysMet: 1.832 ± 0.81
4.974LysAsn: 4.974 ± 0.876
1.571LysPro: 1.571 ± 0.519
2.356LysGln: 2.356 ± 0.99
3.665LysArg: 3.665 ± 1.08
4.712LysSer: 4.712 ± 1.66
4.712LysThr: 4.712 ± 0.93
4.45LysVal: 4.45 ± 0.882
0.524LysTrp: 0.524 ± 0.307
2.356LysTyr: 2.356 ± 1.038
0.0LysXaa: 0.0 ± 0.0
Leu
3.927LeuAla: 3.927 ± 1.044
2.094LeuCys: 2.094 ± 0.498
4.712LeuAsp: 4.712 ± 1.708
3.665LeuGlu: 3.665 ± 0.467
2.88LeuPhe: 2.88 ± 1.062
4.45LeuGly: 4.45 ± 1.26
2.88LeuHis: 2.88 ± 0.474
7.33LeuIle: 7.33 ± 1.16
4.974LeuLys: 4.974 ± 0.853
5.497LeuLeu: 5.497 ± 0.701
4.712LeuMet: 4.712 ± 0.81
4.712LeuAsn: 4.712 ± 0.525
4.712LeuPro: 4.712 ± 0.753
2.094LeuGln: 2.094 ± 0.622
5.236LeuArg: 5.236 ± 1.046
11.257LeuSer: 11.257 ± 1.468
7.068LeuThr: 7.068 ± 1.671
3.927LeuVal: 3.927 ± 1.024
1.309LeuTrp: 1.309 ± 0.581
4.188LeuTyr: 4.188 ± 1.615
0.0LeuXaa: 0.0 ± 0.0
Met
1.832MetAla: 1.832 ± 0.847
1.047MetCys: 1.047 ± 0.979
2.094MetAsp: 2.094 ± 0.63
3.665MetGlu: 3.665 ± 0.995
1.571MetPhe: 1.571 ± 0.66
1.309MetGly: 1.309 ± 0.53
1.047MetHis: 1.047 ± 0.978
3.403MetIle: 3.403 ± 0.94
2.356MetLys: 2.356 ± 0.918
3.403MetLeu: 3.403 ± 2.321
2.094MetMet: 2.094 ± 0.964
2.094MetAsn: 2.094 ± 0.992
1.571MetPro: 1.571 ± 0.759
0.785MetGln: 0.785 ± 0.335
3.403MetArg: 3.403 ± 0.923
3.665MetSer: 3.665 ± 0.839
2.094MetThr: 2.094 ± 0.649
1.571MetVal: 1.571 ± 0.458
0.524MetTrp: 0.524 ± 0.289
1.309MetTyr: 1.309 ± 0.464
0.0MetXaa: 0.0 ± 0.0
Asn
2.094AsnAla: 2.094 ± 0.371
1.571AsnCys: 1.571 ± 0.92
4.188AsnAsp: 4.188 ± 0.832
2.618AsnGlu: 2.618 ± 0.598
1.832AsnPhe: 1.832 ± 0.743
1.571AsnGly: 1.571 ± 0.5
0.262AsnHis: 0.262 ± 0.328
3.665AsnIle: 3.665 ± 0.578
2.618AsnLys: 2.618 ± 1.021
3.403AsnLeu: 3.403 ± 0.991
1.047AsnMet: 1.047 ± 0.535
2.356AsnAsn: 2.356 ± 0.8
3.141AsnPro: 3.141 ± 1.002
1.309AsnGln: 1.309 ± 0.581
3.403AsnArg: 3.403 ± 0.798
1.571AsnSer: 1.571 ± 0.378
3.141AsnThr: 3.141 ± 1.508
3.141AsnVal: 3.141 ± 1.141
1.047AsnTrp: 1.047 ± 0.442
2.356AsnTyr: 2.356 ± 0.94
0.0AsnXaa: 0.0 ± 0.0
Pro
1.309ProAla: 1.309 ± 0.426
0.524ProCys: 0.524 ± 0.307
2.356ProAsp: 2.356 ± 0.506
2.618ProGlu: 2.618 ± 0.762
0.785ProPhe: 0.785 ± 0.26
2.094ProGly: 2.094 ± 0.695
1.309ProHis: 1.309 ± 0.483
2.88ProIle: 2.88 ± 0.73
3.141ProLys: 3.141 ± 0.488
4.188ProLeu: 4.188 ± 1.167
1.571ProMet: 1.571 ± 0.563
1.832ProAsn: 1.832 ± 0.978
2.094ProPro: 2.094 ± 0.795
1.571ProGln: 1.571 ± 0.531
2.094ProArg: 2.094 ± 0.563
3.141ProSer: 3.141 ± 1.145
4.188ProThr: 4.188 ± 1.17
1.309ProVal: 1.309 ± 0.934
0.0ProTrp: 0.0 ± 0.0
1.571ProTyr: 1.571 ± 0.6
0.0ProXaa: 0.0 ± 0.0
Gln
1.832GlnAla: 1.832 ± 0.864
0.785GlnCys: 0.785 ± 0.533
0.262GlnAsp: 0.262 ± 0.153
1.832GlnGlu: 1.832 ± 0.832
1.309GlnPhe: 1.309 ± 1.04
0.524GlnGly: 0.524 ± 0.314
0.262GlnHis: 0.262 ± 0.153
2.618GlnIle: 2.618 ± 0.513
1.047GlnLys: 1.047 ± 0.458
2.094GlnLeu: 2.094 ± 0.552
1.047GlnMet: 1.047 ± 0.614
1.047GlnAsn: 1.047 ± 0.497
1.309GlnPro: 1.309 ± 0.678
1.309GlnGln: 1.309 ± 1.037
2.094GlnArg: 2.094 ± 0.465
2.618GlnSer: 2.618 ± 0.621
1.571GlnThr: 1.571 ± 0.588
2.094GlnVal: 2.094 ± 0.956
0.262GlnTrp: 0.262 ± 0.153
0.524GlnTyr: 0.524 ± 0.45
0.0GlnXaa: 0.0 ± 0.0
Arg
1.832ArgAla: 1.832 ± 0.799
1.309ArgCys: 1.309 ± 0.661
3.403ArgAsp: 3.403 ± 0.87
3.403ArgGlu: 3.403 ± 0.731
2.094ArgPhe: 2.094 ± 0.783
3.403ArgGly: 3.403 ± 0.895
0.262ArgHis: 0.262 ± 0.328
1.571ArgIle: 1.571 ± 0.657
4.712ArgLys: 4.712 ± 1.046
4.188ArgLeu: 4.188 ± 1.224
2.356ArgMet: 2.356 ± 0.781
1.832ArgAsn: 1.832 ± 0.646
1.571ArgPro: 1.571 ± 0.487
1.832ArgGln: 1.832 ± 0.531
2.094ArgArg: 2.094 ± 0.478
3.927ArgSer: 3.927 ± 1.016
3.665ArgThr: 3.665 ± 0.651
2.88ArgVal: 2.88 ± 1.486
0.785ArgTrp: 0.785 ± 0.46
3.141ArgTyr: 3.141 ± 0.795
0.0ArgXaa: 0.0 ± 0.0
Ser
3.665SerAla: 3.665 ± 0.766
1.309SerCys: 1.309 ± 0.568
6.806SerAsp: 6.806 ± 0.968
5.759SerGlu: 5.759 ± 1.27
2.356SerPhe: 2.356 ± 0.558
4.188SerGly: 4.188 ± 1.312
1.309SerHis: 1.309 ± 0.767
3.927SerIle: 3.927 ± 1.188
8.377SerLys: 8.377 ± 0.794
9.424SerLeu: 9.424 ± 0.985
2.356SerMet: 2.356 ± 0.57
2.88SerAsn: 2.88 ± 0.603
2.88SerPro: 2.88 ± 1.103
2.094SerGln: 2.094 ± 2.139
3.665SerArg: 3.665 ± 0.717
9.424SerSer: 9.424 ± 3.062
5.759SerThr: 5.759 ± 1.135
7.068SerVal: 7.068 ± 1.488
1.571SerTrp: 1.571 ± 0.574
4.188SerTyr: 4.188 ± 1.598
0.0SerXaa: 0.0 ± 0.0
Thr
3.927ThrAla: 3.927 ± 1.918
1.047ThrCys: 1.047 ± 0.343
4.188ThrAsp: 4.188 ± 0.769
4.188ThrGlu: 4.188 ± 0.794
3.403ThrPhe: 3.403 ± 0.956
3.665ThrGly: 3.665 ± 0.771
0.785ThrHis: 0.785 ± 0.528
3.927ThrIle: 3.927 ± 0.673
4.712ThrLys: 4.712 ± 1.817
5.497ThrLeu: 5.497 ± 1.668
1.832ThrMet: 1.832 ± 0.614
2.618ThrAsn: 2.618 ± 1.015
3.141ThrPro: 3.141 ± 0.579
1.832ThrGln: 1.832 ± 0.832
2.356ThrArg: 2.356 ± 0.588
6.021ThrSer: 6.021 ± 1.315
2.356ThrThr: 2.356 ± 0.894
4.712ThrVal: 4.712 ± 1.125
1.309ThrTrp: 1.309 ± 0.789
2.356ThrTyr: 2.356 ± 0.779
0.0ThrXaa: 0.0 ± 0.0
Val
3.665ValAla: 3.665 ± 1.267
1.309ValCys: 1.309 ± 0.489
4.45ValAsp: 4.45 ± 0.767
4.712ValGlu: 4.712 ± 1.759
1.832ValPhe: 1.832 ± 0.891
3.665ValGly: 3.665 ± 1.573
1.309ValHis: 1.309 ± 0.522
4.45ValIle: 4.45 ± 1.171
4.712ValLys: 4.712 ± 0.727
3.403ValLeu: 3.403 ± 0.757
1.047ValMet: 1.047 ± 0.442
1.832ValAsn: 1.832 ± 0.74
2.88ValPro: 2.88 ± 0.685
1.047ValGln: 1.047 ± 0.555
3.141ValArg: 3.141 ± 1.184
6.021ValSer: 6.021 ± 0.954
4.974ValThr: 4.974 ± 1.3
3.665ValVal: 3.665 ± 1.642
1.047ValTrp: 1.047 ± 0.497
1.309ValTyr: 1.309 ± 0.314
0.0ValXaa: 0.0 ± 0.0
Trp
0.785TrpAla: 0.785 ± 0.46
0.0TrpCys: 0.0 ± 0.0
1.309TrpAsp: 1.309 ± 0.314
0.524TrpGlu: 0.524 ± 0.307
0.262TrpPhe: 0.262 ± 0.508
1.309TrpGly: 1.309 ± 0.767
0.0TrpHis: 0.0 ± 0.0
1.832TrpIle: 1.832 ± 0.349
1.047TrpLys: 1.047 ± 0.506
1.309TrpLeu: 1.309 ± 0.566
0.262TrpMet: 0.262 ± 0.153
1.571TrpAsn: 1.571 ± 0.398
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.524TrpArg: 0.524 ± 0.307
0.785TrpSer: 0.785 ± 0.533
0.785TrpThr: 0.785 ± 0.26
1.047TrpVal: 1.047 ± 0.678
0.262TrpTrp: 0.262 ± 0.153
0.785TrpTyr: 0.785 ± 0.341
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.047TyrAla: 1.047 ± 1.028
0.262TyrCys: 0.262 ± 0.313
1.571TyrAsp: 1.571 ± 0.66
2.094TyrGlu: 2.094 ± 0.399
1.047TyrPhe: 1.047 ± 0.611
1.309TyrGly: 1.309 ± 0.568
0.785TyrHis: 0.785 ± 0.46
3.403TyrIle: 3.403 ± 1.342
3.403TyrLys: 3.403 ± 0.928
6.545TyrLeu: 6.545 ± 0.87
1.832TyrMet: 1.832 ± 0.884
0.785TyrAsn: 0.785 ± 0.46
1.832TyrPro: 1.832 ± 0.812
1.047TyrGln: 1.047 ± 0.343
2.094TyrArg: 2.094 ± 0.632
3.403TyrSer: 3.403 ± 0.899
2.356TyrThr: 2.356 ± 0.841
2.356TyrVal: 2.356 ± 0.631
0.785TyrTrp: 0.785 ± 0.565
1.309TyrTyr: 1.309 ± 0.857
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3821 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski