Amino acid dipepetide frequency for Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4) (Eubacterium eligens)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.526AlaAla: 6.526 ± 0.114	1.079AlaCys: 1.079 ± 0.041	5.087AlaAsp: 5.087 ± 0.081	4.567AlaGlu: 4.567 ± 0.089	2.894AlaPhe: 2.894 ± 0.069	6.196AlaGly: 6.196 ± 0.1	1.043AlaHis: 1.043 ± 0.037	5.306AlaIle: 5.306 ± 0.092	5.036AlaLys: 5.036 ± 0.095	6.037AlaLeu: 6.037 ± 0.106	2.247AlaMet: 2.247 ± 0.056	2.859AlaAsn: 2.859 ± 0.056	1.708AlaPro: 1.708 ± 0.049	1.994AlaGln: 1.994 ± 0.052	2.584AlaArg: 2.584 ± 0.053	3.98AlaSer: 3.98 ± 0.091	3.366AlaThr: 3.366 ± 0.091	6.346AlaVal: 6.346 ± 0.113	0.493AlaTrp: 0.493 ± 0.023	2.901AlaTyr: 2.901 ± 0.059	0.0AlaXaa: 0.0 ± 0.0
Cys	0.972CysAla: 0.972 ± 0.035	0.247CysCys: 0.247 ± 0.016	0.973CysAsp: 0.973 ± 0.042	0.948CysGlu: 0.948 ± 0.036	0.629CysPhe: 0.629 ± 0.023	1.456CysGly: 1.456 ± 0.053	0.276CysHis: 0.276 ± 0.016	1.317CysIle: 1.317 ± 0.044	0.906CysLys: 0.906 ± 0.035	1.075CysLeu: 1.075 ± 0.035	0.537CysMet: 0.537 ± 0.025	0.761CysAsn: 0.761 ± 0.035	0.498CysPro: 0.498 ± 0.031	0.384CysGln: 0.384 ± 0.019	0.567CysArg: 0.567 ± 0.027	0.875CysSer: 0.875 ± 0.034	0.801CysThr: 0.801 ± 0.036	1.168CysVal: 1.168 ± 0.04	0.104CysTrp: 0.104 ± 0.011	0.597CysTyr: 0.597 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	4.139AspAla: 4.139 ± 0.086	0.885AspCys: 0.885 ± 0.036	3.93AspAsp: 3.93 ± 0.078	5.34AspGlu: 5.34 ± 0.073	2.63AspPhe: 2.63 ± 0.057	4.442AspGly: 4.442 ± 0.088	0.65AspHis: 0.65 ± 0.03	5.912AspIle: 5.912 ± 0.094	4.981AspLys: 4.981 ± 0.083	3.779AspLeu: 3.779 ± 0.074	2.302AspMet: 2.302 ± 0.053	3.905AspAsn: 3.905 ± 0.079	1.363AspPro: 1.363 ± 0.042	0.886AspGln: 0.886 ± 0.033	2.36AspArg: 2.36 ± 0.051	3.719AspSer: 3.719 ± 0.068	3.379AspThr: 3.379 ± 0.067	4.33AspVal: 4.33 ± 0.082	0.499AspTrp: 0.499 ± 0.029	3.369AspTyr: 3.369 ± 0.063	0.0AspXaa: 0.0 ± 0.0
Glu	5.116GluAla: 5.116 ± 0.097	0.981GluCys: 0.981 ± 0.034	4.073GluAsp: 4.073 ± 0.081	5.616GluGlu: 5.616 ± 0.103	2.553GluPhe: 2.553 ± 0.055	3.739GluGly: 3.739 ± 0.073	1.311GluHis: 1.311 ± 0.039	5.317GluIle: 5.317 ± 0.091	6.063GluLys: 6.063 ± 0.089	6.417GluLeu: 6.417 ± 0.098	2.017GluMet: 2.017 ± 0.046	4.117GluAsn: 4.117 ± 0.073	1.588GluPro: 1.588 ± 0.06	2.425GluGln: 2.425 ± 0.053	2.803GluArg: 2.803 ± 0.065	3.592GluSer: 3.592 ± 0.073	3.496GluThr: 3.496 ± 0.068	4.311GluVal: 4.311 ± 0.091	0.547GluTrp: 0.547 ± 0.024	3.595GluTyr: 3.595 ± 0.071	0.0GluXaa: 0.0 ± 0.0
Phe	2.903PheAla: 2.903 ± 0.06	0.637PheCys: 0.637 ± 0.027	2.692PheAsp: 2.692 ± 0.057	2.543PheGlu: 2.543 ± 0.058	1.669PhePhe: 1.669 ± 0.057	2.888PheGly: 2.888 ± 0.068	0.561PheHis: 0.561 ± 0.025	3.366PheIle: 3.366 ± 0.088	2.683PheLys: 2.683 ± 0.056	3.31PheLeu: 3.31 ± 0.073	1.349PheMet: 1.349 ± 0.042	2.205PheAsn: 2.205 ± 0.057	1.145PhePro: 1.145 ± 0.035	0.824PheGln: 0.824 ± 0.03	1.456PheArg: 1.456 ± 0.041	2.661PheSer: 2.661 ± 0.056	2.433PheThr: 2.433 ± 0.061	2.894PheVal: 2.894 ± 0.065	0.324PheTrp: 0.324 ± 0.022	1.728PheTyr: 1.728 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.714GlyAla: 4.714 ± 0.107	1.183GlyCys: 1.183 ± 0.042	3.579GlyAsp: 3.579 ± 0.084	4.128GlyGlu: 4.128 ± 0.072	2.984GlyPhe: 2.984 ± 0.065	4.271GlyGly: 4.271 ± 0.089	1.248GlyHis: 1.248 ± 0.04	6.412GlyIle: 6.412 ± 0.097	5.422GlyLys: 5.422 ± 0.086	5.303GlyLeu: 5.303 ± 0.086	2.391GlyMet: 2.391 ± 0.06	3.408GlyAsn: 3.408 ± 0.066	1.087GlyPro: 1.087 ± 0.041	1.768GlyGln: 1.768 ± 0.047	2.872GlyArg: 2.872 ± 0.063	4.039GlySer: 4.039 ± 0.076	4.167GlyThr: 4.167 ± 0.075	5.037GlyVal: 5.037 ± 0.086	0.607GlyTrp: 0.607 ± 0.026	3.324GlyTyr: 3.324 ± 0.064	0.0GlyXaa: 0.0 ± 0.0
His	0.942HisAla: 0.942 ± 0.032	0.261HisCys: 0.261 ± 0.019	0.876HisAsp: 0.876 ± 0.033	1.011HisGlu: 1.011 ± 0.034	0.802HisPhe: 0.802 ± 0.029	1.137HisGly: 1.137 ± 0.042	0.308HisHis: 0.308 ± 0.027	1.465HisIle: 1.465 ± 0.048	0.973HisLys: 0.973 ± 0.039	1.207HisLeu: 1.207 ± 0.037	0.582HisMet: 0.582 ± 0.026	0.871HisAsn: 0.871 ± 0.032	0.636HisPro: 0.636 ± 0.028	0.4HisGln: 0.4 ± 0.023	0.64HisArg: 0.64 ± 0.028	0.893HisSer: 0.893 ± 0.029	0.827HisThr: 0.827 ± 0.036	1.025HisVal: 1.025 ± 0.037	0.126HisTrp: 0.126 ± 0.011	0.664HisTyr: 0.664 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.121IleAla: 6.121 ± 0.086	1.424IleCys: 1.424 ± 0.046	5.12IleAsp: 5.12 ± 0.08	5.314IleGlu: 5.314 ± 0.082	3.219IlePhe: 3.219 ± 0.085	5.248IleGly: 5.248 ± 0.086	1.269IleHis: 1.269 ± 0.037	7.08IleIle: 7.08 ± 0.12	5.947IleLys: 5.947 ± 0.092	6.548IleLeu: 6.548 ± 0.103	2.568IleMet: 2.568 ± 0.064	4.516IleAsn: 4.516 ± 0.088	2.917IlePro: 2.917 ± 0.063	2.066IleGln: 2.066 ± 0.047	3.244IleArg: 3.244 ± 0.064	5.504IleSer: 5.504 ± 0.088	4.864IleThr: 4.864 ± 0.067	5.728IleVal: 5.728 ± 0.102	0.58IleTrp: 0.58 ± 0.026	3.357IleTyr: 3.357 ± 0.071	0.0IleXaa: 0.0 ± 0.0
Lys	5.591LysAla: 5.591 ± 0.097	1.009LysCys: 1.009 ± 0.038	4.774LysAsp: 4.774 ± 0.074	6.503LysGlu: 6.503 ± 0.105	2.239LysPhe: 2.239 ± 0.052	4.281LysGly: 4.281 ± 0.076	1.138LysHis: 1.138 ± 0.04	5.277LysIle: 5.277 ± 0.077	6.647LysLys: 6.647 ± 0.11	5.818LysLeu: 5.818 ± 0.082	2.461LysMet: 2.461 ± 0.057	4.517LysAsn: 4.517 ± 0.077	2.036LysPro: 2.036 ± 0.05	2.343LysGln: 2.343 ± 0.056	2.97LysArg: 2.97 ± 0.066	3.977LysSer: 3.977 ± 0.064	3.944LysThr: 3.944 ± 0.077	4.598LysVal: 4.598 ± 0.092	0.586LysTrp: 0.586 ± 0.026	3.433LysTyr: 3.433 ± 0.081	0.0LysXaa: 0.0 ± 0.0
Leu	5.857LeuAla: 5.857 ± 0.077	1.307LeuCys: 1.307 ± 0.044	5.0LeuAsp: 5.0 ± 0.077	5.077LeuGlu: 5.077 ± 0.094	3.348LeuPhe: 3.348 ± 0.073	5.347LeuGly: 5.347 ± 0.086	1.298LeuHis: 1.298 ± 0.041	6.536LeuIle: 6.536 ± 0.115	6.183LeuLys: 6.183 ± 0.092	6.546LeuLeu: 6.546 ± 0.104	2.563LeuMet: 2.563 ± 0.06	4.139LeuAsn: 4.139 ± 0.082	2.733LeuPro: 2.733 ± 0.056	2.072LeuGln: 2.072 ± 0.053	3.151LeuArg: 3.151 ± 0.061	5.915LeuSer: 5.915 ± 0.079	4.433LeuThr: 4.433 ± 0.08	5.395LeuVal: 5.395 ± 0.093	0.56LeuTrp: 0.56 ± 0.025	3.124LeuTyr: 3.124 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.486MetAla: 2.486 ± 0.055	0.519MetCys: 0.519 ± 0.027	1.874MetAsp: 1.874 ± 0.051	2.115MetGlu: 2.115 ± 0.05	1.23MetPhe: 1.23 ± 0.045	2.04MetGly: 2.04 ± 0.046	0.52MetHis: 0.52 ± 0.023	2.357MetIle: 2.357 ± 0.056	2.604MetLys: 2.604 ± 0.063	2.845MetLeu: 2.845 ± 0.061	0.972MetMet: 0.972 ± 0.035	1.878MetAsn: 1.878 ± 0.053	1.184MetPro: 1.184 ± 0.038	0.987MetGln: 0.987 ± 0.039	1.252MetArg: 1.252 ± 0.04	2.171MetSer: 2.171 ± 0.051	1.685MetThr: 1.685 ± 0.047	1.999MetVal: 1.999 ± 0.049	0.267MetTrp: 0.267 ± 0.016	1.292MetTyr: 1.292 ± 0.039	0.0MetXaa: 0.0 ± 0.0
Asn	3.79AsnAla: 3.79 ± 0.07	0.689AsnCys: 0.689 ± 0.028	3.041AsnAsp: 3.041 ± 0.063	3.342AsnGlu: 3.342 ± 0.064	1.747AsnPhe: 1.747 ± 0.046	3.904AsnGly: 3.904 ± 0.072	0.768AsnHis: 0.768 ± 0.032	4.931AsnIle: 4.931 ± 0.083	3.686AsnLys: 3.686 ± 0.068	3.935AsnLeu: 3.935 ± 0.065	1.87AsnMet: 1.87 ± 0.05	3.393AsnAsn: 3.393 ± 0.085	2.05AsnPro: 2.05 ± 0.054	1.339AsnGln: 1.339 ± 0.044	2.054AsnArg: 2.054 ± 0.047	3.178AsnSer: 3.178 ± 0.072	2.835AsnThr: 2.835 ± 0.054	4.09AsnVal: 4.09 ± 0.067	0.375AsnTrp: 0.375 ± 0.018	2.246AsnTyr: 2.246 ± 0.059	0.0AsnXaa: 0.0 ± 0.0
Pro	2.057ProAla: 2.057 ± 0.052	0.405ProCys: 0.405 ± 0.025	2.395ProAsp: 2.395 ± 0.056	2.681ProGlu: 2.681 ± 0.069	1.327ProPhe: 1.327 ± 0.044	1.871ProGly: 1.871 ± 0.052	0.477ProHis: 0.477 ± 0.027	1.754ProIle: 1.754 ± 0.045	1.642ProLys: 1.642 ± 0.044	2.218ProLeu: 2.218 ± 0.057	0.765ProMet: 0.765 ± 0.032	0.981ProAsn: 0.981 ± 0.037	0.537ProPro: 0.537 ± 0.024	0.891ProGln: 0.891 ± 0.036	0.824ProArg: 0.824 ± 0.031	1.6ProSer: 1.6 ± 0.044	1.384ProThr: 1.384 ± 0.053	2.83ProVal: 2.83 ± 0.066	0.254ProTrp: 0.254 ± 0.019	1.349ProTyr: 1.349 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.056GlnAla: 2.056 ± 0.053	0.375GlnCys: 0.375 ± 0.021	1.384GlnAsp: 1.384 ± 0.041	1.968GlnGlu: 1.968 ± 0.051	1.084GlnPhe: 1.084 ± 0.032	1.511GlnGly: 1.511 ± 0.04	0.38GlnHis: 0.38 ± 0.021	2.42GlnIle: 2.42 ± 0.06	2.073GlnLys: 2.073 ± 0.053	2.581GlnLeu: 2.581 ± 0.063	1.027GlnMet: 1.027 ± 0.04	1.451GlnAsn: 1.451 ± 0.041	0.725GlnPro: 0.725 ± 0.032	0.952GlnGln: 0.952 ± 0.04	1.086GlnArg: 1.086 ± 0.04	1.445GlnSer: 1.445 ± 0.041	1.439GlnThr: 1.439 ± 0.048	1.697GlnVal: 1.697 ± 0.047	0.241GlnTrp: 0.241 ± 0.017	1.29GlnTyr: 1.29 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	2.247ArgAla: 2.247 ± 0.052	0.568ArgCys: 0.568 ± 0.029	2.081ArgAsp: 2.081 ± 0.051	2.776ArgGlu: 2.776 ± 0.062	1.701ArgPhe: 1.701 ± 0.045	2.071ArgGly: 2.071 ± 0.05	0.716ArgHis: 0.716 ± 0.027	3.532ArgIle: 3.532 ± 0.059	3.362ArgLys: 3.362 ± 0.064	3.396ArgLeu: 3.396 ± 0.072	1.412ArgMet: 1.412 ± 0.042	2.211ArgAsn: 2.211 ± 0.056	1.062ArgPro: 1.062 ± 0.039	1.4ArgGln: 1.4 ± 0.035	1.832ArgArg: 1.832 ± 0.051	1.764ArgSer: 1.764 ± 0.046	2.031ArgThr: 2.031 ± 0.048	2.447ArgVal: 2.447 ± 0.053	0.325ArgTrp: 0.325 ± 0.02	1.86ArgTyr: 1.86 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	4.261SerAla: 4.261 ± 0.07	0.793SerCys: 0.793 ± 0.03	4.291SerAsp: 4.291 ± 0.072	4.181SerGlu: 4.181 ± 0.076	2.538SerPhe: 2.538 ± 0.059	4.94SerGly: 4.94 ± 0.083	0.958SerHis: 0.958 ± 0.031	4.711SerIle: 4.711 ± 0.069	3.935SerLys: 3.935 ± 0.067	4.891SerLeu: 4.891 ± 0.086	1.835SerMet: 1.835 ± 0.056	2.758SerAsn: 2.758 ± 0.063	1.417SerPro: 1.417 ± 0.039	1.837SerGln: 1.837 ± 0.05	2.484SerArg: 2.484 ± 0.056	4.055SerSer: 4.055 ± 0.097	3.027SerThr: 3.027 ± 0.069	4.764SerVal: 4.764 ± 0.082	0.445SerTrp: 0.445 ± 0.026	2.65SerTyr: 2.65 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	4.081ThrAla: 4.081 ± 0.086	0.685ThrCys: 0.685 ± 0.033	3.85ThrAsp: 3.85 ± 0.068	3.551ThrGlu: 3.551 ± 0.088	2.543ThrPhe: 2.543 ± 0.054	4.731ThrGly: 4.731 ± 0.083	0.856ThrHis: 0.856 ± 0.031	4.247ThrIle: 4.247 ± 0.066	3.287ThrLys: 3.287 ± 0.078	4.345ThrLeu: 4.345 ± 0.079	1.436ThrMet: 1.436 ± 0.045	2.273ThrAsn: 2.273 ± 0.056	1.92ThrPro: 1.92 ± 0.053	1.583ThrGln: 1.583 ± 0.048	1.849ThrArg: 1.849 ± 0.045	3.164ThrSer: 3.164 ± 0.077	2.999ThrThr: 2.999 ± 0.074	4.311ThrVal: 4.311 ± 0.092	0.388ThrTrp: 0.388 ± 0.022	2.287ThrTyr: 2.287 ± 0.056	0.0ThrXaa: 0.0 ± 0.0
Val	5.033ValAla: 5.033 ± 0.081	1.266ValCys: 1.266 ± 0.041	4.263ValAsp: 4.263 ± 0.071	4.331ValGlu: 4.331 ± 0.068	2.935ValPhe: 2.935 ± 0.067	4.316ValGly: 4.316 ± 0.084	1.002ValHis: 1.002 ± 0.035	6.204ValIle: 6.204 ± 0.095	5.128ValLys: 5.128 ± 0.084	6.361ValLeu: 6.361 ± 0.103	2.241ValMet: 2.241 ± 0.056	3.795ValAsn: 3.795 ± 0.067	2.227ValPro: 2.227 ± 0.051	1.64ValGln: 1.64 ± 0.046	2.652ValArg: 2.652 ± 0.05	4.999ValSer: 4.999 ± 0.086	4.419ValThr: 4.419 ± 0.086	5.361ValVal: 5.361 ± 0.09	0.572ValTrp: 0.572 ± 0.026	3.052ValTyr: 3.052 ± 0.065	0.0ValXaa: 0.0 ± 0.0
Trp	0.463TrpAla: 0.463 ± 0.023	0.137TrpCys: 0.137 ± 0.012	0.438TrpAsp: 0.438 ± 0.022	0.531TrpGlu: 0.531 ± 0.026	0.359TrpPhe: 0.359 ± 0.022	0.559TrpGly: 0.559 ± 0.029	0.16TrpHis: 0.16 ± 0.014	0.624TrpIle: 0.624 ± 0.026	0.588TrpLys: 0.588 ± 0.027	0.751TrpLeu: 0.751 ± 0.036	0.278TrpMet: 0.278 ± 0.017	0.477TrpAsn: 0.477 ± 0.023	0.167TrpPro: 0.167 ± 0.015	0.27TrpGln: 0.27 ± 0.015	0.312TrpArg: 0.312 ± 0.02	0.386TrpSer: 0.386 ± 0.023	0.348TrpThr: 0.348 ± 0.02	0.465TrpVal: 0.465 ± 0.025	0.09TrpTrp: 0.09 ± 0.012	0.324TrpTyr: 0.324 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.896TyrAla: 2.896 ± 0.052	0.638TyrCys: 0.638 ± 0.028	3.079TyrAsp: 3.079 ± 0.065	3.151TyrGlu: 3.151 ± 0.065	1.844TyrPhe: 1.844 ± 0.045	2.998TyrGly: 2.998 ± 0.063	0.709TyrHis: 0.709 ± 0.031	3.864TyrIle: 3.864 ± 0.076	2.997TyrLys: 2.997 ± 0.07	3.224TyrLeu: 3.224 ± 0.06	1.424TyrMet: 1.424 ± 0.041	2.745TyrAsn: 2.745 ± 0.063	1.239TyrPro: 1.239 ± 0.04	1.124TyrGln: 1.124 ± 0.035	1.804TyrArg: 1.804 ± 0.047	2.853TyrSer: 2.853 ± 0.071	2.507TyrThr: 2.507 ± 0.064	3.002TyrVal: 3.002 ± 0.058	0.345TyrTrp: 0.345 ± 0.02	2.075TyrTyr: 2.075 ± 0.059	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2761 proteins (855239 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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