Amino acid dipepetide frequency for Papaya mosaic potexvirus (PMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.984AlaAla: 6.984 ± 4.372
0.822AlaCys: 0.822 ± 0.791
2.054AlaAsp: 2.054 ± 1.023
3.287AlaGlu: 3.287 ± 1.104
4.108AlaPhe: 4.108 ± 1.928
4.108AlaGly: 4.108 ± 1.391
2.465AlaHis: 2.465 ± 0.903
5.752AlaIle: 5.752 ± 2.227
3.698AlaLys: 3.698 ± 1.073
10.271AlaLeu: 10.271 ± 3.101
1.643AlaMet: 1.643 ± 0.674
4.108AlaAsn: 4.108 ± 1.331
2.465AlaPro: 2.465 ± 1.281
2.054AlaGln: 2.054 ± 1.308
4.519AlaArg: 4.519 ± 2.148
6.163AlaSer: 6.163 ± 2.33
4.108AlaThr: 4.108 ± 1.127
3.287AlaVal: 3.287 ± 1.483
1.643AlaTrp: 1.643 ± 0.673
2.876AlaTyr: 2.876 ± 0.776
0.0AlaXaa: 0.0 ± 0.0
Cys
0.822CysAla: 0.822 ± 1.257
0.411CysCys: 0.411 ± 0.933
0.0CysAsp: 0.0 ± 0.0
0.822CysGlu: 0.822 ± 0.896
1.233CysPhe: 1.233 ± 0.697
0.822CysGly: 0.822 ± 0.462
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
2.054CysLys: 2.054 ± 1.213
2.876CysLeu: 2.876 ± 2.188
0.822CysMet: 0.822 ± 1.225
0.411CysAsn: 0.411 ± 0.231
2.465CysPro: 2.465 ± 2.394
1.233CysGln: 1.233 ± 0.697
2.054CysArg: 2.054 ± 0.629
0.822CysSer: 0.822 ± 0.647
2.054CysThr: 2.054 ± 1.366
0.411CysVal: 0.411 ± 0.231
0.0CysTrp: 0.0 ± 0.0
0.822CysTyr: 0.822 ± 0.687
0.0CysXaa: 0.0 ± 0.0
Asp
2.054AspAla: 2.054 ± 1.155
0.822AspCys: 0.822 ± 0.647
2.465AspAsp: 2.465 ± 1.012
2.465AspGlu: 2.465 ± 1.058
0.822AspPhe: 0.822 ± 0.687
3.287AspGly: 3.287 ± 0.829
1.643AspHis: 1.643 ± 0.729
2.054AspIle: 2.054 ± 0.828
0.822AspLys: 0.822 ± 0.687
2.876AspLeu: 2.876 ± 0.936
0.411AspMet: 0.411 ± 0.231
3.287AspAsn: 3.287 ± 1.68
4.519AspPro: 4.519 ± 1.126
1.233AspGln: 1.233 ± 1.012
0.822AspArg: 0.822 ± 1.083
1.233AspSer: 1.233 ± 0.693
1.233AspThr: 1.233 ± 0.693
2.876AspVal: 2.876 ± 1.267
1.233AspTrp: 1.233 ± 0.697
1.643AspTyr: 1.643 ± 0.924
0.0AspXaa: 0.0 ± 0.0
Glu
6.984GluAla: 6.984 ± 1.826
1.643GluCys: 1.643 ± 0.672
2.465GluAsp: 2.465 ± 1.385
6.163GluGlu: 6.163 ± 2.386
2.465GluPhe: 2.465 ± 1.058
2.876GluGly: 2.876 ± 1.085
0.411GluHis: 0.411 ± 0.231
3.698GluIle: 3.698 ± 0.905
6.574GluLys: 6.574 ± 2.895
6.574GluLeu: 6.574 ± 1.932
1.643GluMet: 1.643 ± 0.654
2.054GluAsn: 2.054 ± 0.778
4.93GluPro: 4.93 ± 2.056
3.698GluGln: 3.698 ± 1.282
1.643GluArg: 1.643 ± 0.674
2.876GluSer: 2.876 ± 1.147
3.287GluThr: 3.287 ± 1.482
4.519GluVal: 4.519 ± 2.078
1.643GluTrp: 1.643 ± 0.924
1.643GluTyr: 1.643 ± 0.991
0.0GluXaa: 0.0 ± 0.0
Phe
2.465PheAla: 2.465 ± 1.909
1.643PheCys: 1.643 ± 1.374
3.698PheAsp: 3.698 ± 1.437
2.465PheGlu: 2.465 ± 1.385
0.822PhePhe: 0.822 ± 0.687
2.876PheGly: 2.876 ± 1.82
1.233PheHis: 1.233 ± 0.693
2.876PheIle: 2.876 ± 0.934
4.519PheLys: 4.519 ± 1.289
5.752PheLeu: 5.752 ± 0.516
1.233PheMet: 1.233 ± 0.693
2.054PheAsn: 2.054 ± 0.861
1.643PhePro: 1.643 ± 1.302
2.876PheGln: 2.876 ± 0.597
1.643PheArg: 1.643 ± 0.674
4.108PheSer: 4.108 ± 1.434
1.233PheThr: 1.233 ± 0.64
0.822PheVal: 0.822 ± 0.495
0.411PheTrp: 0.411 ± 0.231
0.411PheTyr: 0.411 ± 0.231
0.0PheXaa: 0.0 ± 0.0
Gly
4.108GlyAla: 4.108 ± 1.493
1.233GlyCys: 1.233 ± 0.572
2.876GlyAsp: 2.876 ± 1.007
1.643GlyGlu: 1.643 ± 0.924
2.465GlyPhe: 2.465 ± 0.798
4.519GlyGly: 4.519 ± 1.628
2.465GlyHis: 2.465 ± 1.072
2.876GlyIle: 2.876 ± 1.54
4.519GlyLys: 4.519 ± 1.658
4.93GlyLeu: 4.93 ± 1.312
0.822GlyMet: 0.822 ± 0.462
1.233GlyAsn: 1.233 ± 0.854
4.108GlyPro: 4.108 ± 1.503
2.465GlyGln: 2.465 ± 1.897
2.876GlyArg: 2.876 ± 1.267
2.876GlySer: 2.876 ± 1.443
3.698GlyThr: 3.698 ± 2.287
2.876GlyVal: 2.876 ± 1.438
0.822GlyTrp: 0.822 ± 0.462
1.233GlyTyr: 1.233 ± 0.64
0.0GlyXaa: 0.0 ± 0.0
His
2.054HisAla: 2.054 ± 1.155
0.411HisCys: 0.411 ± 0.542
0.0HisAsp: 0.0 ± 0.0
1.643HisGlu: 1.643 ± 0.924
2.465HisPhe: 2.465 ± 1.066
2.054HisGly: 2.054 ± 0.881
0.822HisHis: 0.822 ± 0.462
1.233HisIle: 1.233 ± 0.693
2.876HisLys: 2.876 ± 1.267
2.876HisLeu: 2.876 ± 0.857
0.822HisMet: 0.822 ± 0.462
0.0HisAsn: 0.0 ± 0.0
1.233HisPro: 1.233 ± 0.693
2.054HisGln: 2.054 ± 0.793
2.465HisArg: 2.465 ± 1.066
4.108HisSer: 4.108 ± 2.098
2.054HisThr: 2.054 ± 1.213
0.822HisVal: 0.822 ± 0.956
0.411HisTrp: 0.411 ± 0.231
0.822HisTyr: 0.822 ± 0.495
0.0HisXaa: 0.0 ± 0.0
Ile
4.519IleAla: 4.519 ± 1.33
0.0IleCys: 0.0 ± 0.0
0.822IleAsp: 0.822 ± 0.555
6.163IleGlu: 6.163 ± 1.925
3.698IlePhe: 3.698 ± 1.041
1.643IleGly: 1.643 ± 1.216
1.643IleHis: 1.643 ± 0.672
2.465IleIle: 2.465 ± 2.612
5.752IleLys: 5.752 ± 2.164
4.519IleLeu: 4.519 ± 1.533
0.411IleMet: 0.411 ± 0.231
1.643IleAsn: 1.643 ± 0.685
2.876IlePro: 2.876 ± 1.108
3.287IleGln: 3.287 ± 0.963
2.465IleArg: 2.465 ± 0.669
4.108IleSer: 4.108 ± 1.315
3.698IleThr: 3.698 ± 1.463
2.465IleVal: 2.465 ± 1.199
1.233IleTrp: 1.233 ± 0.861
1.233IleTyr: 1.233 ± 0.618
0.0IleXaa: 0.0 ± 0.0
Lys
5.752LysAla: 5.752 ± 1.564
1.233LysCys: 1.233 ± 1.714
4.108LysAsp: 4.108 ± 1.924
4.93LysGlu: 4.93 ± 1.812
3.698LysPhe: 3.698 ± 1.581
5.341LysGly: 5.341 ± 1.172
1.643LysHis: 1.643 ± 0.924
2.876LysIle: 2.876 ± 1.616
5.341LysLys: 5.341 ± 2.527
7.395LysLeu: 7.395 ± 2.684
2.876LysMet: 2.876 ± 0.799
2.876LysAsn: 2.876 ± 0.998
4.519LysPro: 4.519 ± 1.332
1.643LysGln: 1.643 ± 0.674
3.287LysArg: 3.287 ± 1.827
5.341LysSer: 5.341 ± 2.399
5.752LysThr: 5.752 ± 2.103
2.054LysVal: 2.054 ± 1.372
0.411LysTrp: 0.411 ± 0.231
2.054LysTyr: 2.054 ± 0.828
0.0LysXaa: 0.0 ± 0.0
Leu
7.395LeuAla: 7.395 ± 2.536
1.643LeuCys: 1.643 ± 0.685
4.519LeuAsp: 4.519 ± 1.537
5.752LeuGlu: 5.752 ± 1.87
3.698LeuPhe: 3.698 ± 1.123
3.698LeuGly: 3.698 ± 1.529
4.93LeuHis: 4.93 ± 1.424
4.93LeuIle: 4.93 ± 2.756
4.93LeuLys: 4.93 ± 2.976
6.984LeuLeu: 6.984 ± 1.778
0.822LeuMet: 0.822 ± 0.687
2.465LeuAsn: 2.465 ± 1.187
7.806LeuPro: 7.806 ± 1.756
4.519LeuGln: 4.519 ± 2.148
9.039LeuArg: 9.039 ± 2.122
7.395LeuSer: 7.395 ± 2.969
8.628LeuThr: 8.628 ± 2.062
4.93LeuVal: 4.93 ± 1.594
0.822LeuTrp: 0.822 ± 0.462
3.287LeuTyr: 3.287 ± 1.422
0.0LeuXaa: 0.0 ± 0.0
Met
2.054MetAla: 2.054 ± 0.665
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.643MetGlu: 1.643 ± 0.924
1.643MetPhe: 1.643 ± 0.873
1.233MetGly: 1.233 ± 0.693
1.233MetHis: 1.233 ± 0.693
0.822MetIle: 0.822 ± 0.462
1.643MetLys: 1.643 ± 1.914
1.643MetLeu: 1.643 ± 0.924
0.0MetMet: 0.0 ± 0.0
0.411MetAsn: 0.411 ± 0.542
1.643MetPro: 1.643 ± 0.924
0.822MetGln: 0.822 ± 1.382
2.054MetArg: 2.054 ± 0.727
2.054MetSer: 2.054 ± 2.955
0.822MetThr: 0.822 ± 0.791
2.054MetVal: 2.054 ± 0.665
0.0MetTrp: 0.0 ± 0.0
0.411MetTyr: 0.411 ± 0.231
0.0MetXaa: 0.0 ± 0.0
Asn
3.287AsnAla: 3.287 ± 0.891
2.465AsnCys: 2.465 ± 1.317
1.233AsnAsp: 1.233 ± 0.693
1.643AsnGlu: 1.643 ± 0.685
1.643AsnPhe: 1.643 ± 2.054
1.233AsnGly: 1.233 ± 0.64
2.054AsnHis: 2.054 ± 1.213
1.643AsnIle: 1.643 ± 0.729
1.643AsnLys: 1.643 ± 0.674
3.698AsnLeu: 3.698 ± 1.342
1.233AsnMet: 1.233 ± 1.364
1.233AsnAsn: 1.233 ± 1.199
4.519AsnPro: 4.519 ± 1.052
0.822AsnGln: 0.822 ± 0.462
1.233AsnArg: 1.233 ± 0.697
1.643AsnSer: 1.643 ± 0.84
2.465AsnThr: 2.465 ± 0.824
3.287AsnVal: 3.287 ± 1.482
1.233AsnTrp: 1.233 ± 0.64
0.822AsnTyr: 0.822 ± 0.896
0.0AsnXaa: 0.0 ± 0.0
Pro
3.287ProAla: 3.287 ± 2.749
1.643ProCys: 1.643 ± 0.828
2.465ProAsp: 2.465 ± 1.018
9.449ProGlu: 9.449 ± 2.085
3.287ProPhe: 3.287 ± 0.834
2.465ProGly: 2.465 ± 1.235
1.233ProHis: 1.233 ± 1.362
5.752ProIle: 5.752 ± 1.136
6.163ProLys: 6.163 ± 2.671
4.519ProLeu: 4.519 ± 2.95
0.0ProMet: 0.0 ± 0.0
4.519ProAsn: 4.519 ± 0.762
4.108ProPro: 4.108 ± 2.292
2.876ProGln: 2.876 ± 0.871
0.822ProArg: 0.822 ± 0.462
4.519ProSer: 4.519 ± 3.906
4.93ProThr: 4.93 ± 2.326
3.698ProVal: 3.698 ± 1.175
0.411ProTrp: 0.411 ± 0.231
2.054ProTyr: 2.054 ± 0.727
0.0ProXaa: 0.0 ± 0.0
Gln
4.108GlnAla: 4.108 ± 1.165
0.411GlnCys: 0.411 ± 0.231
1.233GlnAsp: 1.233 ± 0.64
4.108GlnGlu: 4.108 ± 1.797
1.643GlnPhe: 1.643 ± 0.674
1.233GlnGly: 1.233 ± 0.693
1.233GlnHis: 1.233 ± 0.819
2.465GlnIle: 2.465 ± 0.673
3.698GlnLys: 3.698 ± 1.382
5.341GlnLeu: 5.341 ± 1.1
1.233GlnMet: 1.233 ± 0.788
1.643GlnAsn: 1.643 ± 0.952
2.054GlnPro: 2.054 ± 1.04
2.876GlnGln: 2.876 ± 1.616
1.643GlnArg: 1.643 ± 1.581
1.643GlnSer: 1.643 ± 0.672
1.643GlnThr: 1.643 ± 0.924
2.054GlnVal: 2.054 ± 1.04
1.233GlnTrp: 1.233 ± 1.714
1.233GlnTyr: 1.233 ± 0.551
0.0GlnXaa: 0.0 ± 0.0
Arg
4.519ArgAla: 4.519 ± 1.493
2.465ArgCys: 2.465 ± 2.66
3.287ArgAsp: 3.287 ± 1.459
2.876ArgGlu: 2.876 ± 1.212
2.465ArgPhe: 2.465 ± 1.071
3.287ArgGly: 3.287 ± 1.332
0.822ArgHis: 0.822 ± 0.495
2.465ArgIle: 2.465 ± 0.824
2.465ArgLys: 2.465 ± 1.428
2.876ArgLeu: 2.876 ± 1.267
0.411ArgMet: 0.411 ± 0.231
1.233ArgAsn: 1.233 ± 1.01
3.287ArgPro: 3.287 ± 2.041
2.465ArgGln: 2.465 ± 0.771
2.054ArgArg: 2.054 ± 0.743
4.108ArgSer: 4.108 ± 0.851
1.643ArgThr: 1.643 ± 1.16
0.411ArgVal: 0.411 ± 0.231
0.0ArgTrp: 0.0 ± 0.0
1.643ArgTyr: 1.643 ± 0.674
0.0ArgXaa: 0.0 ± 0.0
Ser
3.698SerAla: 3.698 ± 4.01
0.411SerCys: 0.411 ± 0.629
1.643SerAsp: 1.643 ± 1.183
3.287SerGlu: 3.287 ± 1.482
1.643SerPhe: 1.643 ± 0.674
6.574SerGly: 6.574 ± 3.951
2.465SerHis: 2.465 ± 1.066
4.108SerIle: 4.108 ± 1.852
3.698SerLys: 3.698 ± 0.845
7.395SerLeu: 7.395 ± 1.274
2.876SerMet: 2.876 ± 1.349
2.876SerAsn: 2.876 ± 1.226
5.341SerPro: 5.341 ± 1.679
2.876SerGln: 2.876 ± 0.873
2.465SerArg: 2.465 ± 1.112
5.752SerSer: 5.752 ± 3.803
4.93SerThr: 4.93 ± 2.383
3.287SerVal: 3.287 ± 1.166
1.233SerTrp: 1.233 ± 0.572
2.054SerTyr: 2.054 ± 0.793
0.0SerXaa: 0.0 ± 0.0
Thr
3.698ThrAla: 3.698 ± 0.936
2.054ThrCys: 2.054 ± 2.033
1.643ThrAsp: 1.643 ± 0.673
2.876ThrGlu: 2.876 ± 1.267
2.054ThrPhe: 2.054 ± 1.155
3.698ThrGly: 3.698 ± 1.154
2.876ThrHis: 2.876 ± 1.267
3.287ThrIle: 3.287 ± 0.891
3.287ThrLys: 3.287 ± 0.858
7.395ThrLeu: 7.395 ± 1.598
1.643ThrMet: 1.643 ± 0.751
2.876ThrAsn: 2.876 ± 0.792
6.574ThrPro: 6.574 ± 2.04
2.054ThrGln: 2.054 ± 1.936
0.411ThrArg: 0.411 ± 0.933
5.341ThrSer: 5.341 ± 2.767
3.698ThrThr: 3.698 ± 1.186
4.519ThrVal: 4.519 ± 1.557
0.0ThrTrp: 0.0 ± 0.0
2.465ThrTyr: 2.465 ± 0.955
0.0ThrXaa: 0.0 ± 0.0
Val
4.519ValAla: 4.519 ± 1.362
0.411ValCys: 0.411 ± 0.992
1.643ValAsp: 1.643 ± 0.734
2.465ValGlu: 2.465 ± 0.667
2.054ValPhe: 2.054 ± 0.937
2.876ValGly: 2.876 ± 1.982
1.643ValHis: 1.643 ± 0.673
2.876ValIle: 2.876 ± 1.225
4.93ValLys: 4.93 ± 1.659
6.574ValLeu: 6.574 ± 2.127
1.233ValMet: 1.233 ± 0.572
1.643ValAsn: 1.643 ± 0.673
1.643ValPro: 1.643 ± 0.734
2.054ValGln: 2.054 ± 1.155
1.643ValArg: 1.643 ± 1.228
2.876ValSer: 2.876 ± 0.776
4.93ValThr: 4.93 ± 1.094
2.876ValVal: 2.876 ± 1.989
0.0ValTrp: 0.0 ± 0.0
1.643ValTyr: 1.643 ± 0.694
0.0ValXaa: 0.0 ± 0.0
Trp
2.054TrpAla: 2.054 ± 1.155
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.233TrpGlu: 1.233 ± 1.201
0.822TrpPhe: 0.822 ± 0.462
0.411TrpGly: 0.411 ± 0.231
0.0TrpHis: 0.0 ± 0.0
0.822TrpIle: 0.822 ± 0.462
1.643TrpLys: 1.643 ± 0.673
0.822TrpLeu: 0.822 ± 0.462
0.411TrpMet: 0.411 ± 0.231
1.233TrpAsn: 1.233 ± 1.201
0.822TrpPro: 0.822 ± 0.555
0.411TrpGln: 0.411 ± 0.231
0.0TrpArg: 0.0 ± 0.0
0.411TrpSer: 0.411 ± 0.933
0.0TrpThr: 0.0 ± 0.0
1.643TrpVal: 1.643 ± 0.673
0.822TrpTrp: 0.822 ± 0.791
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.054TyrAla: 2.054 ± 0.828
0.411TyrCys: 0.411 ± 0.542
1.643TyrAsp: 1.643 ± 0.674
2.876TyrGlu: 2.876 ± 1.616
2.054TyrPhe: 2.054 ± 0.91
0.411TyrGly: 0.411 ± 0.231
0.411TyrHis: 0.411 ± 0.231
1.643TyrIle: 1.643 ± 0.685
2.876TyrLys: 2.876 ± 0.754
2.876TyrLeu: 2.876 ± 1.616
1.233TyrMet: 1.233 ± 0.865
1.233TyrAsn: 1.233 ± 0.618
1.643TyrPro: 1.643 ± 0.694
0.411TyrGln: 0.411 ± 0.231
1.643TyrArg: 1.643 ± 1.183
1.233TyrSer: 1.233 ± 0.693
2.054TyrThr: 2.054 ± 0.629
1.643TyrVal: 1.643 ± 0.685
0.0TyrTrp: 0.0 ± 0.0
0.822TyrTyr: 0.822 ± 0.462
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2435 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski