Amino acid dipepetide frequency for Hamster polyomavirus (HaPyV) (Mesocricetus auratus polyomavirus 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.38AlaAla: 4.38 ± 1.406
0.0AlaCys: 0.0 ± 0.0
3.504AlaAsp: 3.504 ± 0.581
4.38AlaGlu: 4.38 ± 1.209
2.19AlaPhe: 2.19 ± 0.999
1.752AlaGly: 1.752 ± 0.506
1.752AlaHis: 1.752 ± 0.714
3.942AlaIle: 3.942 ± 1.229
3.066AlaLys: 3.066 ± 1.565
7.446AlaLeu: 7.446 ± 1.601
0.438AlaMet: 0.438 ± 0.476
4.818AlaAsn: 4.818 ± 1.681
3.066AlaPro: 3.066 ± 1.293
2.628AlaGln: 2.628 ± 0.938
2.628AlaArg: 2.628 ± 0.767
1.752AlaSer: 1.752 ± 0.493
0.0AlaThr: 0.0 ± 0.0
4.818AlaVal: 4.818 ± 1.314
0.438AlaTrp: 0.438 ± 0.295
1.314AlaTyr: 1.314 ± 0.686
0.0AlaXaa: 0.0 ± 0.0
Cys
0.438CysAla: 0.438 ± 0.295
0.438CysCys: 0.438 ± 0.295
1.752CysAsp: 1.752 ± 0.766
0.876CysGlu: 0.876 ± 0.59
0.876CysPhe: 0.876 ± 0.624
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.19CysIle: 2.19 ± 1.155
2.628CysLys: 2.628 ± 1.082
4.38CysLeu: 4.38 ± 2.31
0.438CysMet: 0.438 ± 0.295
1.314CysAsn: 1.314 ± 0.567
0.876CysPro: 0.876 ± 0.415
1.314CysGln: 1.314 ± 0.885
0.876CysArg: 0.876 ± 0.624
0.0CysSer: 0.0 ± 0.0
0.438CysThr: 0.438 ± 0.295
0.438CysVal: 0.438 ± 0.295
0.0CysTrp: 0.0 ± 0.0
2.19CysTyr: 2.19 ± 1.155
0.0CysXaa: 0.0 ± 0.0
Asp
2.19AspAla: 2.19 ± 1.308
0.876AspCys: 0.876 ± 0.624
1.314AspAsp: 1.314 ± 0.885
3.066AspGlu: 3.066 ± 0.839
1.752AspPhe: 1.752 ± 1.179
3.066AspGly: 3.066 ± 1.063
0.0AspHis: 0.0 ± 0.0
3.066AspIle: 3.066 ± 0.963
4.818AspLys: 4.818 ± 1.474
5.256AspLeu: 5.256 ± 0.851
0.876AspMet: 0.876 ± 0.358
0.876AspAsn: 0.876 ± 0.59
2.628AspPro: 2.628 ± 0.773
1.752AspGln: 1.752 ± 0.654
1.314AspArg: 1.314 ± 0.567
1.752AspSer: 1.752 ± 0.553
3.066AspThr: 3.066 ± 0.436
3.504AspVal: 3.504 ± 1.106
2.19AspTrp: 2.19 ± 0.603
3.066AspTyr: 3.066 ± 0.726
0.0AspXaa: 0.0 ± 0.0
Glu
6.132GluAla: 6.132 ± 2.297
0.876GluCys: 0.876 ± 0.624
4.818GluAsp: 4.818 ± 0.953
7.884GluGlu: 7.884 ± 2.552
2.628GluPhe: 2.628 ± 1.356
2.19GluGly: 2.19 ± 1.956
0.0GluHis: 0.0 ± 0.0
1.314GluIle: 1.314 ± 0.411
3.504GluLys: 3.504 ± 1.61
7.008GluLeu: 7.008 ± 1.81
1.314GluMet: 1.314 ± 0.543
4.818GluAsn: 4.818 ± 1.224
2.628GluPro: 2.628 ± 1.03
0.438GluGln: 0.438 ± 0.295
1.752GluArg: 1.752 ± 0.481
3.942GluSer: 3.942 ± 1.108
2.628GluThr: 2.628 ± 0.614
4.818GluVal: 4.818 ± 0.856
0.0GluTrp: 0.0 ± 0.0
4.38GluTyr: 4.38 ± 1.297
0.0GluXaa: 0.0 ± 0.0
Phe
3.942PheAla: 3.942 ± 0.402
0.876PheCys: 0.876 ± 0.59
0.438PheAsp: 0.438 ± 0.295
3.066PheGlu: 3.066 ± 1.383
1.752PhePhe: 1.752 ± 0.822
1.314PheGly: 1.314 ± 0.567
0.438PheHis: 0.438 ± 0.295
2.19PheIle: 2.19 ± 0.7
0.0PheLys: 0.0 ± 0.0
7.008PheLeu: 7.008 ± 2.056
0.876PheMet: 0.876 ± 0.358
0.876PheAsn: 0.876 ± 0.415
3.066PhePro: 3.066 ± 1.014
2.628PheGln: 2.628 ± 1.217
1.314PheArg: 1.314 ± 0.567
3.504PheSer: 3.504 ± 0.553
2.628PheThr: 2.628 ± 0.705
0.876PheVal: 0.876 ± 0.358
0.0PheTrp: 0.0 ± 0.0
0.438PheTyr: 0.438 ± 0.295
0.0PheXaa: 0.0 ± 0.0
Gly
3.504GlyAla: 3.504 ± 1.744
0.0GlyCys: 0.0 ± 0.0
3.942GlyAsp: 3.942 ± 0.399
3.942GlyGlu: 3.942 ± 1.266
1.752GlyPhe: 1.752 ± 0.407
6.57GlyGly: 6.57 ± 0.536
1.314GlyHis: 1.314 ± 0.52
3.942GlyIle: 3.942 ± 0.525
2.628GlyLys: 2.628 ± 0.647
6.57GlyLeu: 6.57 ± 1.045
0.876GlyMet: 0.876 ± 0.749
1.314GlyAsn: 1.314 ± 0.567
3.942GlyPro: 3.942 ± 0.8
2.628GlyGln: 2.628 ± 1.676
3.504GlyArg: 3.504 ± 0.342
3.942GlySer: 3.942 ± 1.165
3.504GlyThr: 3.504 ± 2.75
3.942GlyVal: 3.942 ± 1.574
1.752GlyTrp: 1.752 ± 1.049
1.752GlyTyr: 1.752 ± 0.506
0.0GlyXaa: 0.0 ± 0.0
His
1.752HisAla: 1.752 ± 0.648
0.438HisCys: 0.438 ± 0.295
0.0HisAsp: 0.0 ± 0.0
1.314HisGlu: 1.314 ± 0.707
1.314HisPhe: 1.314 ± 0.567
1.752HisGly: 1.752 ± 0.906
0.876HisHis: 0.876 ± 0.411
0.438HisIle: 0.438 ± 0.375
0.876HisLys: 0.876 ± 0.411
2.628HisLeu: 2.628 ± 1.234
0.438HisMet: 0.438 ± 0.476
0.876HisAsn: 0.876 ± 0.411
1.752HisPro: 1.752 ± 0.654
2.628HisGln: 2.628 ± 1.121
0.876HisArg: 0.876 ± 0.59
1.314HisSer: 1.314 ± 0.52
0.876HisThr: 0.876 ± 0.415
0.438HisVal: 0.438 ± 0.295
0.876HisTrp: 0.876 ± 0.415
0.438HisTyr: 0.438 ± 0.295
0.0HisXaa: 0.0 ± 0.0
Ile
1.314IleAla: 1.314 ± 0.52
0.438IleCys: 0.438 ± 0.295
3.942IleAsp: 3.942 ± 0.402
3.504IleGlu: 3.504 ± 1.87
2.628IlePhe: 2.628 ± 0.802
0.876IleGly: 0.876 ± 0.615
1.314IleHis: 1.314 ± 0.56
1.314IleIle: 1.314 ± 0.411
1.314IleLys: 1.314 ± 0.914
6.132IleLeu: 6.132 ± 1.323
2.628IleMet: 2.628 ± 0.705
1.314IleAsn: 1.314 ± 0.52
3.504IlePro: 3.504 ± 1.402
1.314IleGln: 1.314 ± 0.541
0.876IleArg: 0.876 ± 0.411
6.132IleSer: 6.132 ± 1.489
2.19IleThr: 2.19 ± 0.93
1.314IleVal: 1.314 ± 0.48
0.876IleTrp: 0.876 ± 0.543
2.19IleTyr: 2.19 ± 0.402
0.0IleXaa: 0.0 ± 0.0
Lys
1.752LysAla: 1.752 ± 1.305
3.942LysCys: 3.942 ± 1.478
3.942LysAsp: 3.942 ± 0.903
3.066LysGlu: 3.066 ± 1.338
0.876LysPhe: 0.876 ± 0.59
3.504LysGly: 3.504 ± 0.942
1.752LysHis: 1.752 ± 0.865
0.438LysIle: 0.438 ± 0.476
9.636LysLys: 9.636 ± 2.208
3.504LysLeu: 3.504 ± 0.783
0.876LysMet: 0.876 ± 0.749
0.438LysAsn: 0.438 ± 0.476
4.38LysPro: 4.38 ± 2.988
3.504LysGln: 3.504 ± 1.308
4.38LysArg: 4.38 ± 1.286
3.504LysSer: 3.504 ± 1.357
1.752LysThr: 1.752 ± 0.831
3.066LysVal: 3.066 ± 1.585
0.438LysTrp: 0.438 ± 0.295
1.752LysTyr: 1.752 ± 0.459
0.0LysXaa: 0.0 ± 0.0
Leu
4.38LeuAla: 4.38 ± 0.896
2.628LeuCys: 2.628 ± 1.045
8.322LeuAsp: 8.322 ± 1.184
7.008LeuGlu: 7.008 ± 2.145
4.38LeuPhe: 4.38 ± 1.143
7.008LeuGly: 7.008 ± 1.924
2.19LeuHis: 2.19 ± 0.593
4.818LeuIle: 4.818 ± 0.907
4.38LeuLys: 4.38 ± 1.683
10.074LeuLeu: 10.074 ± 2.688
3.942LeuMet: 3.942 ± 2.176
5.256LeuAsn: 5.256 ± 1.061
7.446LeuPro: 7.446 ± 1.997
5.256LeuGln: 5.256 ± 0.968
4.818LeuArg: 4.818 ± 1.298
6.57LeuSer: 6.57 ± 1.281
6.132LeuThr: 6.132 ± 1.363
3.942LeuVal: 3.942 ± 1.17
3.066LeuTrp: 3.066 ± 0.95
6.57LeuTyr: 6.57 ± 0.823
0.0LeuXaa: 0.0 ± 0.0
Met
1.752MetAla: 1.752 ± 0.62
1.314MetCys: 1.314 ± 0.541
1.314MetAsp: 1.314 ± 0.567
1.752MetGlu: 1.752 ± 0.906
1.752MetPhe: 1.752 ± 0.506
2.628MetGly: 2.628 ± 0.666
0.438MetHis: 0.438 ± 0.375
0.876MetIle: 0.876 ± 0.484
0.876MetLys: 0.876 ± 0.59
3.942MetLeu: 3.942 ± 0.74
1.314MetMet: 1.314 ± 0.52
0.876MetAsn: 0.876 ± 0.411
0.438MetPro: 0.438 ± 0.375
3.504MetGln: 3.504 ± 0.905
1.752MetArg: 1.752 ± 0.62
0.0MetSer: 0.0 ± 0.0
1.752MetThr: 1.752 ± 0.407
0.0MetVal: 0.0 ± 0.0
0.438MetTrp: 0.438 ± 0.476
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.752AsnAla: 1.752 ± 0.766
1.752AsnCys: 1.752 ± 0.654
0.0AsnAsp: 0.0 ± 0.0
3.504AsnGlu: 3.504 ± 0.869
2.19AsnPhe: 2.19 ± 1.474
0.876AsnGly: 0.876 ± 0.415
0.438AsnHis: 0.438 ± 0.295
1.314AsnIle: 1.314 ± 0.52
3.504AsnLys: 3.504 ± 1.071
3.504AsnLeu: 3.504 ± 0.933
2.19AsnMet: 2.19 ± 0.987
0.876AsnAsn: 0.876 ± 0.415
4.38AsnPro: 4.38 ± 0.292
1.314AsnGln: 1.314 ± 0.914
2.19AsnArg: 2.19 ± 0.833
5.256AsnSer: 5.256 ± 0.67
3.504AsnThr: 3.504 ± 0.966
4.38AsnVal: 4.38 ± 1.106
0.0AsnTrp: 0.0 ± 0.0
1.752AsnTyr: 1.752 ± 1.049
0.0AsnXaa: 0.0 ± 0.0
Pro
5.694ProAla: 5.694 ± 1.036
1.752ProCys: 1.752 ± 0.493
5.256ProAsp: 5.256 ± 0.912
1.314ProGlu: 1.314 ± 0.784
0.0ProPhe: 0.0 ± 0.0
5.694ProGly: 5.694 ± 1.233
0.0ProHis: 0.0 ± 0.0
3.504ProIle: 3.504 ± 1.691
2.628ProLys: 2.628 ± 0.814
5.256ProLeu: 5.256 ± 0.581
1.314ProMet: 1.314 ± 0.633
2.19ProAsn: 2.19 ± 1.14
6.57ProPro: 6.57 ± 2.577
2.628ProGln: 2.628 ± 1.158
3.942ProArg: 3.942 ± 1.074
2.628ProSer: 2.628 ± 0.599
4.38ProThr: 4.38 ± 0.837
5.694ProVal: 5.694 ± 1.656
0.438ProTrp: 0.438 ± 0.295
0.876ProTyr: 0.876 ± 0.952
0.0ProXaa: 0.0 ± 0.0
Gln
2.628GlnAla: 2.628 ± 0.792
0.876GlnCys: 0.876 ± 0.59
0.876GlnAsp: 0.876 ± 0.411
3.066GlnGlu: 3.066 ± 0.985
2.19GlnPhe: 2.19 ± 0.744
1.314GlnGly: 1.314 ± 0.686
2.19GlnHis: 2.19 ± 0.715
3.942GlnIle: 3.942 ± 0.705
2.628GlnLys: 2.628 ± 0.983
3.942GlnLeu: 3.942 ± 0.903
0.876GlnMet: 0.876 ± 0.657
2.19GlnAsn: 2.19 ± 0.891
0.876GlnPro: 0.876 ± 0.415
6.57GlnGln: 6.57 ± 0.929
3.942GlnArg: 3.942 ± 1.458
3.942GlnSer: 3.942 ± 1.115
5.256GlnThr: 5.256 ± 1.305
3.066GlnVal: 3.066 ± 1.167
0.876GlnTrp: 0.876 ± 0.624
2.19GlnTyr: 2.19 ± 0.715
0.0GlnXaa: 0.0 ± 0.0
Arg
1.314ArgAla: 1.314 ± 0.52
0.0ArgCys: 0.0 ± 0.0
1.314ArgAsp: 1.314 ± 0.52
3.504ArgGlu: 3.504 ± 1.166
1.752ArgPhe: 1.752 ± 0.553
2.628ArgGly: 2.628 ± 1.082
0.876ArgHis: 0.876 ± 0.59
2.628ArgIle: 2.628 ± 0.484
3.066ArgLys: 3.066 ± 0.954
5.694ArgLeu: 5.694 ± 2.775
3.066ArgMet: 3.066 ± 0.298
3.504ArgAsn: 3.504 ± 1.421
3.066ArgPro: 3.066 ± 1.551
2.628ArgGln: 2.628 ± 0.94
8.76ArgArg: 8.76 ± 2.796
2.19ArgSer: 2.19 ± 0.402
1.314ArgThr: 1.314 ± 0.61
4.38ArgVal: 4.38 ± 1.13
1.314ArgTrp: 1.314 ± 0.686
1.752ArgTyr: 1.752 ± 1.049
0.0ArgXaa: 0.0 ± 0.0
Ser
3.066SerAla: 3.066 ± 1.268
0.876SerCys: 0.876 ± 0.59
1.314SerAsp: 1.314 ± 0.885
1.752SerGlu: 1.752 ± 0.747
2.19SerPhe: 2.19 ± 0.568
4.38SerGly: 4.38 ± 1.272
1.314SerHis: 1.314 ± 0.61
3.504SerIle: 3.504 ± 1.288
0.876SerLys: 0.876 ± 0.415
9.636SerLeu: 9.636 ± 1.543
0.438SerMet: 0.438 ± 0.476
1.314SerAsn: 1.314 ± 0.52
3.942SerPro: 3.942 ± 1.284
5.256SerGln: 5.256 ± 1.049
4.38SerArg: 4.38 ± 1.297
7.446SerSer: 7.446 ± 1.986
5.256SerThr: 5.256 ± 1.237
3.504SerVal: 3.504 ± 1.716
1.752SerTrp: 1.752 ± 0.736
3.066SerTyr: 3.066 ± 1.284
0.0SerXaa: 0.0 ± 0.0
Thr
3.066ThrAla: 3.066 ± 0.995
2.628ThrCys: 2.628 ± 1.045
0.876ThrAsp: 0.876 ± 0.415
3.504ThrGlu: 3.504 ± 1.17
1.752ThrPhe: 1.752 ± 0.654
4.38ThrGly: 4.38 ± 1.956
2.19ThrHis: 2.19 ± 1.038
1.752ThrIle: 1.752 ± 0.459
4.38ThrLys: 4.38 ± 0.913
6.132ThrLeu: 6.132 ± 1.666
0.876ThrMet: 0.876 ± 0.358
2.628ThrAsn: 2.628 ± 1.01
3.942ThrPro: 3.942 ± 1.445
3.942ThrGln: 3.942 ± 1.09
0.876ThrArg: 0.876 ± 0.411
4.818ThrSer: 4.818 ± 0.844
3.066ThrThr: 3.066 ± 0.839
2.628ThrVal: 2.628 ± 0.96
0.876ThrTrp: 0.876 ± 0.543
2.19ThrTyr: 2.19 ± 0.744
0.0ThrXaa: 0.0 ± 0.0
Val
2.628ValAla: 2.628 ± 1.356
0.438ValCys: 0.438 ± 0.295
1.314ValAsp: 1.314 ± 0.567
3.942ValGlu: 3.942 ± 1.265
0.438ValPhe: 0.438 ± 0.295
3.504ValGly: 3.504 ± 2.231
2.19ValHis: 2.19 ± 0.457
1.752ValIle: 1.752 ± 0.714
3.504ValLys: 3.504 ± 1.449
5.694ValLeu: 5.694 ± 0.611
1.752ValMet: 1.752 ± 0.886
3.504ValAsn: 3.504 ± 1.17
4.38ValPro: 4.38 ± 1.124
2.628ValGln: 2.628 ± 1.361
3.942ValArg: 3.942 ± 1.072
2.19ValSer: 2.19 ± 0.918
7.008ValThr: 7.008 ± 1.668
1.752ValVal: 1.752 ± 0.553
0.0ValTrp: 0.0 ± 0.0
1.314ValTyr: 1.314 ± 0.567
0.0ValXaa: 0.0 ± 0.0
Trp
0.438TrpAla: 0.438 ± 0.295
0.0TrpCys: 0.0 ± 0.0
1.314TrpAsp: 1.314 ± 0.52
0.876TrpGlu: 0.876 ± 0.415
1.752TrpPhe: 1.752 ± 0.736
2.19TrpGly: 2.19 ± 0.603
0.876TrpHis: 0.876 ± 0.415
0.0TrpIle: 0.0 ± 0.0
0.438TrpLys: 0.438 ± 0.476
0.876TrpLeu: 0.876 ± 0.624
0.876TrpMet: 0.876 ± 0.543
1.752TrpAsn: 1.752 ± 0.654
0.0TrpPro: 0.0 ± 0.0
0.876TrpGln: 0.876 ± 0.543
1.314TrpArg: 1.314 ± 0.672
0.438TrpSer: 0.438 ± 0.295
1.314TrpThr: 1.314 ± 0.567
1.314TrpVal: 1.314 ± 0.686
0.0TrpTrp: 0.0 ± 0.0
0.876TrpTyr: 0.876 ± 0.415
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.19TyrAla: 2.19 ± 0.603
1.314TyrCys: 1.314 ± 0.567
0.876TyrAsp: 0.876 ± 0.543
1.752TyrGlu: 1.752 ± 0.763
3.066TyrPhe: 3.066 ± 0.298
5.694TyrGly: 5.694 ± 1.495
1.752TyrHis: 1.752 ± 0.638
2.19TyrIle: 2.19 ± 1.142
1.752TyrLys: 1.752 ± 0.654
3.504TyrLeu: 3.504 ± 0.748
0.876TyrMet: 0.876 ± 0.411
3.942TyrAsn: 3.942 ± 1.009
0.876TyrPro: 0.876 ± 0.415
0.438TyrGln: 0.438 ± 0.295
1.314TyrArg: 1.314 ± 0.567
3.942TyrSer: 3.942 ± 0.785
0.0TyrThr: 0.0 ± 0.0
0.0TyrVal: 0.0 ± 0.0
2.19TyrTrp: 2.19 ± 0.842
2.628TyrTyr: 2.628 ± 1.373
0.438TyrXaa: 0.438 ± 0.476
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.438XaaThr: 0.438 ± 0.476
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
8.76XaaXaa: 8.76 ± 9.521
Statistics based on 6 proteins (2284 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski