Amino acid dipepetide frequency for Mesocricetus auratus papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.377AlaAla: 4.377 ± 1.011
3.183AlaCys: 3.183 ± 1.579
4.377AlaAsp: 4.377 ± 0.988
5.173AlaGlu: 5.173 ± 1.792
2.786AlaPhe: 2.786 ± 1.036
3.979AlaGly: 3.979 ± 1.643
0.796AlaHis: 0.796 ± 0.718
1.194AlaIle: 1.194 ± 0.694
2.786AlaLys: 2.786 ± 0.833
6.367AlaLeu: 6.367 ± 1.219
1.194AlaMet: 1.194 ± 0.336
2.786AlaAsn: 2.786 ± 0.762
4.377AlaPro: 4.377 ± 0.95
1.99AlaGln: 1.99 ± 0.712
3.979AlaArg: 3.979 ± 0.824
5.173AlaSer: 5.173 ± 0.88
5.969AlaThr: 5.969 ± 1.274
1.99AlaVal: 1.99 ± 1.213
0.0AlaTrp: 0.0 ± 0.0
1.99AlaTyr: 1.99 ± 0.885
0.0AlaXaa: 0.0 ± 0.0
Cys
1.194CysAla: 1.194 ± 0.416
0.398CysCys: 0.398 ± 0.286
1.592CysAsp: 1.592 ± 0.824
1.194CysGlu: 1.194 ± 0.571
0.796CysPhe: 0.796 ± 0.596
0.796CysGly: 0.796 ± 0.402
0.398CysHis: 0.398 ± 0.359
1.194CysIle: 1.194 ± 0.778
0.796CysLys: 0.796 ± 0.718
3.581CysLeu: 3.581 ± 1.419
1.194CysMet: 1.194 ± 0.989
0.0CysAsn: 0.0 ± 0.0
2.388CysPro: 2.388 ± 1.832
1.194CysGln: 1.194 ± 0.457
1.592CysArg: 1.592 ± 1.939
1.592CysSer: 1.592 ± 1.145
1.194CysThr: 1.194 ± 0.578
1.99CysVal: 1.99 ± 2.209
1.194CysTrp: 1.194 ± 0.416
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.775AspAla: 4.775 ± 1.235
1.194AspCys: 1.194 ± 0.623
3.979AspAsp: 3.979 ± 1.585
4.775AspGlu: 4.775 ± 1.105
2.388AspPhe: 2.388 ± 1.293
2.388AspGly: 2.388 ± 0.931
0.398AspHis: 0.398 ± 0.33
5.969AspIle: 5.969 ± 2.543
2.388AspLys: 2.388 ± 0.671
6.765AspLeu: 6.765 ± 1.142
1.592AspMet: 1.592 ± 0.665
2.388AspAsn: 2.388 ± 0.484
4.377AspPro: 4.377 ± 0.706
3.581AspGln: 3.581 ± 1.967
3.183AspArg: 3.183 ± 0.972
6.367AspSer: 6.367 ± 1.675
3.581AspThr: 3.581 ± 1.008
3.581AspVal: 3.581 ± 1.538
0.796AspTrp: 0.796 ± 0.402
3.183AspTyr: 3.183 ± 0.831
0.0AspXaa: 0.0 ± 0.0
Glu
3.581GluAla: 3.581 ± 1.222
0.796GluCys: 0.796 ± 0.572
5.173GluAsp: 5.173 ± 1.254
4.377GluGlu: 4.377 ± 1.684
1.99GluPhe: 1.99 ± 1.012
6.367GluGly: 6.367 ± 2.349
0.796GluHis: 0.796 ± 0.402
2.786GluIle: 2.786 ± 0.96
2.388GluLys: 2.388 ± 1.02
3.581GluLeu: 3.581 ± 0.842
0.398GluMet: 0.398 ± 0.286
2.786GluAsn: 2.786 ± 1.0
3.581GluPro: 3.581 ± 1.494
3.979GluGln: 3.979 ± 1.228
2.786GluArg: 2.786 ± 0.86
2.786GluSer: 2.786 ± 0.983
3.183GluThr: 3.183 ± 1.316
3.581GluVal: 3.581 ± 1.003
0.398GluTrp: 0.398 ± 0.286
1.592GluTyr: 1.592 ± 0.567
0.0GluXaa: 0.0 ± 0.0
Phe
2.388PheAla: 2.388 ± 0.687
1.194PheCys: 1.194 ± 0.578
3.183PheAsp: 3.183 ± 0.977
1.592PheGlu: 1.592 ± 0.567
2.388PhePhe: 2.388 ± 0.832
2.786PheGly: 2.786 ± 0.767
1.194PheHis: 1.194 ± 0.563
1.592PheIle: 1.592 ± 0.567
1.99PheLys: 1.99 ± 0.833
5.571PheLeu: 5.571 ± 2.284
1.99PheMet: 1.99 ± 0.827
1.194PheAsn: 1.194 ± 0.706
1.592PhePro: 1.592 ± 0.701
2.388PheGln: 2.388 ± 0.834
1.99PheArg: 1.99 ± 0.435
1.99PheSer: 1.99 ± 0.597
1.194PheThr: 1.194 ± 0.416
1.99PheVal: 1.99 ± 1.503
1.194PheTrp: 1.194 ± 0.706
1.592PheTyr: 1.592 ± 0.598
0.0PheXaa: 0.0 ± 0.0
Gly
4.377GlyAla: 4.377 ± 1.232
1.194GlyCys: 1.194 ± 0.598
4.775GlyAsp: 4.775 ± 0.848
3.979GlyGlu: 3.979 ± 1.405
2.388GlyPhe: 2.388 ± 0.832
6.367GlyGly: 6.367 ± 3.213
0.398GlyHis: 0.398 ± 0.359
3.979GlyIle: 3.979 ± 1.136
2.786GlyLys: 2.786 ± 0.703
4.377GlyLeu: 4.377 ± 1.49
1.194GlyMet: 1.194 ± 0.833
5.173GlyAsn: 5.173 ± 1.328
6.367GlyPro: 6.367 ± 1.627
2.786GlyGln: 2.786 ± 0.829
5.173GlyArg: 5.173 ± 1.921
3.581GlySer: 3.581 ± 0.868
5.173GlyThr: 5.173 ± 2.126
4.775GlyVal: 4.775 ± 1.233
0.398GlyTrp: 0.398 ± 0.286
1.592GlyTyr: 1.592 ± 0.687
0.0GlyXaa: 0.0 ± 0.0
His
0.796HisAla: 0.796 ± 0.397
0.796HisCys: 0.796 ± 0.572
0.796HisAsp: 0.796 ± 0.718
1.194HisGlu: 1.194 ± 0.563
0.796HisPhe: 0.796 ± 0.621
0.398HisGly: 0.398 ± 0.497
0.0HisHis: 0.0 ± 0.0
0.398HisIle: 0.398 ± 0.485
0.796HisLys: 0.796 ± 0.596
1.194HisLeu: 1.194 ± 0.336
0.398HisMet: 0.398 ± 0.382
0.398HisAsn: 0.398 ± 0.33
1.592HisPro: 1.592 ± 0.554
1.194HisGln: 1.194 ± 0.563
1.194HisArg: 1.194 ± 0.578
0.796HisSer: 0.796 ± 0.416
0.398HisThr: 0.398 ± 0.359
1.592HisVal: 1.592 ± 0.825
0.796HisTrp: 0.796 ± 0.402
0.796HisTyr: 0.796 ± 0.397
0.0HisXaa: 0.0 ± 0.0
Ile
4.775IleAla: 4.775 ± 1.341
1.194IleCys: 1.194 ± 0.682
1.592IleAsp: 1.592 ± 0.448
3.183IleGlu: 3.183 ± 1.709
1.592IlePhe: 1.592 ± 0.733
3.979IleGly: 3.979 ± 1.17
0.398IleHis: 0.398 ± 0.359
1.194IleIle: 1.194 ± 0.701
1.592IleLys: 1.592 ± 0.517
2.388IleLeu: 2.388 ± 0.77
0.398IleMet: 0.398 ± 0.497
2.388IleAsn: 2.388 ± 1.609
2.786IlePro: 2.786 ± 0.514
3.581IleGln: 3.581 ± 0.807
1.194IleArg: 1.194 ± 0.607
5.173IleSer: 5.173 ± 1.49
3.183IleThr: 3.183 ± 0.774
2.786IleVal: 2.786 ± 0.808
0.0IleTrp: 0.0 ± 0.0
2.388IleTyr: 2.388 ± 0.909
0.0IleXaa: 0.0 ± 0.0
Lys
2.388LysAla: 2.388 ± 0.821
1.592LysCys: 1.592 ± 0.778
3.183LysAsp: 3.183 ± 1.579
1.99LysGlu: 1.99 ± 0.713
1.592LysPhe: 1.592 ± 0.667
1.99LysGly: 1.99 ± 0.884
1.194LysHis: 1.194 ± 0.634
1.592LysIle: 1.592 ± 0.517
2.786LysLys: 2.786 ± 0.904
3.979LysLeu: 3.979 ± 0.728
1.194LysMet: 1.194 ± 0.697
1.194LysAsn: 1.194 ± 0.623
1.99LysPro: 1.99 ± 1.146
1.592LysGln: 1.592 ± 0.593
4.775LysArg: 4.775 ± 0.678
3.581LysSer: 3.581 ± 1.529
2.786LysThr: 2.786 ± 1.03
4.377LysVal: 4.377 ± 0.944
0.398LysTrp: 0.398 ± 0.359
3.183LysTyr: 3.183 ± 0.983
0.0LysXaa: 0.0 ± 0.0
Leu
5.173LeuAla: 5.173 ± 1.246
0.796LeuCys: 0.796 ± 0.829
5.969LeuAsp: 5.969 ± 1.073
3.979LeuGlu: 3.979 ± 0.823
6.367LeuPhe: 6.367 ± 2.489
9.55LeuGly: 9.55 ± 2.101
3.183LeuHis: 3.183 ± 0.805
3.581LeuIle: 3.581 ± 0.989
4.377LeuLys: 4.377 ± 1.222
9.152LeuLeu: 9.152 ± 2.286
0.796LeuMet: 0.796 ± 0.55
1.592LeuAsn: 1.592 ± 0.776
4.775LeuPro: 4.775 ± 1.553
3.183LeuGln: 3.183 ± 0.564
5.173LeuArg: 5.173 ± 1.244
7.561LeuSer: 7.561 ± 1.527
3.581LeuThr: 3.581 ± 1.008
5.969LeuVal: 5.969 ± 0.954
0.796LeuTrp: 0.796 ± 0.596
5.571LeuTyr: 5.571 ± 1.223
0.0LeuXaa: 0.0 ± 0.0
Met
1.194MetAla: 1.194 ± 0.64
0.796MetCys: 0.796 ± 0.59
1.194MetAsp: 1.194 ± 0.701
0.398MetGlu: 0.398 ± 0.578
1.194MetPhe: 1.194 ± 0.706
0.398MetGly: 0.398 ± 0.33
0.398MetHis: 0.398 ± 0.33
0.796MetIle: 0.796 ± 0.572
0.796MetLys: 0.796 ± 0.511
1.194MetLeu: 1.194 ± 0.634
0.0MetMet: 0.0 ± 0.0
1.592MetAsn: 1.592 ± 0.656
0.398MetPro: 0.398 ± 0.33
0.796MetGln: 0.796 ± 0.622
1.99MetArg: 1.99 ± 0.668
1.592MetSer: 1.592 ± 0.691
0.398MetThr: 0.398 ± 0.359
1.592MetVal: 1.592 ± 0.788
0.398MetTrp: 0.398 ± 0.359
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.592AsnAla: 1.592 ± 0.516
1.194AsnCys: 1.194 ± 0.457
2.388AsnAsp: 2.388 ± 0.797
1.194AsnGlu: 1.194 ± 0.598
1.592AsnPhe: 1.592 ± 1.151
1.194AsnGly: 1.194 ± 0.682
0.398AsnHis: 0.398 ± 0.497
2.388AsnIle: 2.388 ± 0.684
2.388AsnLys: 2.388 ± 0.927
3.183AsnLeu: 3.183 ± 0.962
0.398AsnMet: 0.398 ± 0.33
1.592AsnAsn: 1.592 ± 0.783
4.377AsnPro: 4.377 ± 1.209
0.796AsnGln: 0.796 ± 0.718
3.581AsnArg: 3.581 ± 0.696
2.388AsnSer: 2.388 ± 1.096
1.99AsnThr: 1.99 ± 0.703
3.183AsnVal: 3.183 ± 0.953
0.398AsnTrp: 0.398 ± 0.286
0.796AsnTyr: 0.796 ± 0.403
0.0AsnXaa: 0.0 ± 0.0
Pro
6.765ProAla: 6.765 ± 2.555
1.99ProCys: 1.99 ± 0.799
7.959ProAsp: 7.959 ± 2.011
4.775ProGlu: 4.775 ± 1.574
1.592ProPhe: 1.592 ± 0.701
3.979ProGly: 3.979 ± 2.7
0.796ProHis: 0.796 ± 0.416
4.775ProIle: 4.775 ± 0.79
2.786ProLys: 2.786 ± 1.32
7.561ProLeu: 7.561 ± 2.093
0.398ProMet: 0.398 ± 0.286
1.592ProAsn: 1.592 ± 1.151
10.346ProPro: 10.346 ± 4.629
1.592ProGln: 1.592 ± 0.854
4.377ProArg: 4.377 ± 1.716
6.367ProSer: 6.367 ± 1.651
3.979ProThr: 3.979 ± 1.55
1.592ProVal: 1.592 ± 0.812
0.398ProTrp: 0.398 ± 0.33
1.592ProTyr: 1.592 ± 1.072
0.0ProXaa: 0.0 ± 0.0
Gln
2.388GlnAla: 2.388 ± 0.968
1.194GlnCys: 1.194 ± 0.476
3.979GlnAsp: 3.979 ± 0.898
2.388GlnGlu: 2.388 ± 1.389
2.388GlnPhe: 2.388 ± 0.924
3.183GlnGly: 3.183 ± 0.696
0.796GlnHis: 0.796 ± 0.511
2.388GlnIle: 2.388 ± 0.571
1.592GlnLys: 1.592 ± 1.151
3.581GlnLeu: 3.581 ± 1.34
0.796GlnMet: 0.796 ± 0.397
1.194GlnAsn: 1.194 ± 0.618
1.99GlnPro: 1.99 ± 0.627
1.592GlnGln: 1.592 ± 0.556
2.786GlnArg: 2.786 ± 0.961
3.979GlnSer: 3.979 ± 0.681
3.183GlnThr: 3.183 ± 0.849
1.194GlnVal: 1.194 ± 0.564
1.194GlnTrp: 1.194 ± 0.634
1.99GlnTyr: 1.99 ± 0.748
0.0GlnXaa: 0.0 ± 0.0
Arg
3.581ArgAla: 3.581 ± 0.703
1.592ArgCys: 1.592 ± 0.824
1.592ArgAsp: 1.592 ± 0.806
2.388ArgGlu: 2.388 ± 0.559
2.786ArgPhe: 2.786 ± 1.18
5.173ArgGly: 5.173 ± 1.767
1.99ArgHis: 1.99 ± 0.799
2.786ArgIle: 2.786 ± 1.698
5.173ArgLys: 5.173 ± 0.968
7.163ArgLeu: 7.163 ± 0.788
1.592ArgMet: 1.592 ± 0.526
2.388ArgAsn: 2.388 ± 0.513
4.775ArgPro: 4.775 ± 1.408
3.183ArgGln: 3.183 ± 0.651
5.969ArgArg: 5.969 ± 1.478
3.183ArgSer: 3.183 ± 0.852
3.979ArgThr: 3.979 ± 0.968
3.979ArgVal: 3.979 ± 1.463
0.0ArgTrp: 0.0 ± 0.0
1.592ArgTyr: 1.592 ± 0.282
0.0ArgXaa: 0.0 ± 0.0
Ser
3.183SerAla: 3.183 ± 0.953
1.592SerCys: 1.592 ± 1.422
4.377SerAsp: 4.377 ± 0.886
5.969SerGlu: 5.969 ± 2.319
2.388SerPhe: 2.388 ± 1.389
5.571SerGly: 5.571 ± 1.371
1.592SerHis: 1.592 ± 0.534
2.388SerIle: 2.388 ± 0.909
4.775SerLys: 4.775 ± 2.46
8.754SerLeu: 8.754 ± 1.507
0.796SerMet: 0.796 ± 0.481
1.194SerAsn: 1.194 ± 0.604
5.571SerPro: 5.571 ± 1.402
2.388SerGln: 2.388 ± 0.832
2.786SerArg: 2.786 ± 1.483
6.367SerSer: 6.367 ± 1.153
5.571SerThr: 5.571 ± 1.517
3.979SerVal: 3.979 ± 1.424
0.398SerTrp: 0.398 ± 0.33
1.99SerTyr: 1.99 ± 0.65
0.0SerXaa: 0.0 ± 0.0
Thr
4.377ThrAla: 4.377 ± 1.166
1.592ThrCys: 1.592 ± 0.645
4.775ThrAsp: 4.775 ± 1.374
3.183ThrGlu: 3.183 ± 0.799
1.99ThrPhe: 1.99 ± 0.736
6.367ThrGly: 6.367 ± 2.043
0.398ThrHis: 0.398 ± 0.352
2.388ThrIle: 2.388 ± 1.203
0.796ThrLys: 0.796 ± 0.433
3.979ThrLeu: 3.979 ± 0.806
0.398ThrMet: 0.398 ± 0.286
1.99ThrAsn: 1.99 ± 0.652
6.367ThrPro: 6.367 ± 2.707
2.786ThrGln: 2.786 ± 0.988
3.979ThrArg: 3.979 ± 0.447
3.183ThrSer: 3.183 ± 0.858
3.979ThrThr: 3.979 ± 0.714
5.571ThrVal: 5.571 ± 1.029
0.796ThrTrp: 0.796 ± 0.66
0.398ThrTyr: 0.398 ± 0.352
0.0ThrXaa: 0.0 ± 0.0
Val
2.388ValAla: 2.388 ± 1.566
1.194ValCys: 1.194 ± 1.344
4.775ValAsp: 4.775 ± 1.649
3.183ValGlu: 3.183 ± 1.038
1.592ValPhe: 1.592 ± 0.516
3.183ValGly: 3.183 ± 1.166
1.194ValHis: 1.194 ± 0.636
2.786ValIle: 2.786 ± 1.216
2.786ValLys: 2.786 ± 0.556
4.377ValLeu: 4.377 ± 1.177
1.194ValMet: 1.194 ± 0.336
3.979ValAsn: 3.979 ± 0.815
5.571ValPro: 5.571 ± 3.031
3.183ValGln: 3.183 ± 1.137
5.173ValArg: 5.173 ± 1.398
5.173ValSer: 5.173 ± 1.343
3.183ValThr: 3.183 ± 1.603
4.377ValVal: 4.377 ± 1.026
0.398ValTrp: 0.398 ± 0.359
1.194ValTyr: 1.194 ± 0.682
0.0ValXaa: 0.0 ± 0.0
Trp
0.398TrpAla: 0.398 ± 0.286
0.0TrpCys: 0.0 ± 0.0
0.796TrpAsp: 0.796 ± 0.397
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.398TrpGly: 0.398 ± 0.359
0.398TrpHis: 0.398 ± 0.33
0.0TrpIle: 0.0 ± 0.0
0.796TrpLys: 0.796 ± 0.416
0.796TrpLeu: 0.796 ± 0.402
0.398TrpMet: 0.398 ± 0.359
0.398TrpAsn: 0.398 ± 0.359
0.398TrpPro: 0.398 ± 0.359
0.398TrpGln: 0.398 ± 0.286
1.592TrpArg: 1.592 ± 0.598
0.0TrpSer: 0.0 ± 0.0
1.592TrpThr: 1.592 ± 0.932
1.592TrpVal: 1.592 ± 0.891
0.0TrpTrp: 0.0 ± 0.0
0.398TrpTyr: 0.398 ± 0.286
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.775TyrAla: 4.775 ± 1.848
0.796TyrCys: 0.796 ± 0.622
1.194TyrAsp: 1.194 ± 0.634
1.99TyrGlu: 1.99 ± 1.132
2.388TyrPhe: 2.388 ± 1.187
2.786TyrGly: 2.786 ± 0.875
0.0TyrHis: 0.0 ± 0.0
1.592TyrIle: 1.592 ± 1.046
2.786TyrLys: 2.786 ± 0.867
3.581TyrLeu: 3.581 ± 1.171
0.398TyrMet: 0.398 ± 0.286
1.194TyrAsn: 1.194 ± 0.416
1.592TyrPro: 1.592 ± 0.701
1.592TyrGln: 1.592 ± 0.567
1.592TyrArg: 1.592 ± 0.535
0.796TyrSer: 0.796 ± 0.588
1.194TyrThr: 1.194 ± 0.329
1.194TyrVal: 1.194 ± 0.457
0.398TyrTrp: 0.398 ± 0.33
2.388TyrTyr: 2.388 ± 0.89
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2514 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski