Amino acid dipepetide frequency for Torque teno Leptonychotes weddellii virus-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.305AlaAla: 1.305 ± 1.745
1.305AlaCys: 1.305 ± 0.644
0.0AlaAsp: 0.0 ± 0.0
1.305AlaGlu: 1.305 ± 0.644
0.0AlaPhe: 0.0 ± 0.0
0.0AlaGly: 0.0 ± 0.0
1.305AlaHis: 1.305 ± 1.745
1.305AlaIle: 1.305 ± 0.644
2.611AlaLys: 2.611 ± 1.288
2.611AlaLeu: 2.611 ± 3.489
1.305AlaMet: 1.305 ± 0.644
1.305AlaAsn: 1.305 ± 0.644
1.305AlaPro: 1.305 ± 0.644
0.0AlaGln: 0.0 ± 0.0
0.0AlaArg: 0.0 ± 0.0
2.611AlaSer: 2.611 ± 1.288
5.222AlaThr: 5.222 ± 1.455
0.0AlaVal: 0.0 ± 0.0
1.305AlaTrp: 1.305 ± 0.644
2.611AlaTyr: 2.611 ± 1.288
0.0AlaXaa: 0.0 ± 0.0
Cys
1.305CysAla: 1.305 ± 1.745
0.0CysCys: 0.0 ± 0.0
1.305CysAsp: 1.305 ± 0.644
0.0CysGlu: 0.0 ± 0.0
1.305CysPhe: 1.305 ± 2.109
1.305CysGly: 1.305 ± 1.745
1.305CysHis: 1.305 ± 0.644
0.0CysIle: 0.0 ± 0.0
2.611CysLys: 2.611 ± 1.288
1.305CysLeu: 1.305 ± 1.745
0.0CysMet: 0.0 ± 0.0
1.305CysAsn: 1.305 ± 0.644
2.611CysPro: 2.611 ± 1.288
1.305CysGln: 1.305 ± 0.644
1.305CysArg: 1.305 ± 2.109
2.611CysSer: 2.611 ± 1.587
0.0CysThr: 0.0 ± 0.0
2.611CysVal: 2.611 ± 1.708
1.305CysTrp: 1.305 ± 0.644
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.305AspCys: 1.305 ± 0.644
1.305AspAsp: 1.305 ± 0.644
2.611AspGlu: 2.611 ± 2.992
1.305AspPhe: 1.305 ± 0.644
5.222AspGly: 5.222 ± 1.455
0.0AspHis: 0.0 ± 0.0
3.916AspIle: 3.916 ± 1.263
0.0AspLys: 0.0 ± 0.0
9.138AspLeu: 9.138 ± 2.712
1.305AspMet: 1.305 ± 0.644
1.305AspAsn: 1.305 ± 0.644
2.611AspPro: 2.611 ± 1.708
3.916AspGln: 3.916 ± 1.263
3.916AspArg: 3.916 ± 1.263
7.833AspSer: 7.833 ± 3.043
5.222AspThr: 5.222 ± 1.455
2.611AspVal: 2.611 ± 1.587
1.305AspTrp: 1.305 ± 0.644
2.611AspTyr: 2.611 ± 1.288
0.0AspXaa: 0.0 ± 0.0
Glu
3.916GluAla: 3.916 ± 1.263
1.305GluCys: 1.305 ± 1.885
5.222GluAsp: 5.222 ± 1.7
2.611GluGlu: 2.611 ± 1.38
1.305GluPhe: 1.305 ± 1.885
7.833GluGly: 7.833 ± 4.372
0.0GluHis: 0.0 ± 0.0
3.916GluIle: 3.916 ± 2.156
1.305GluLys: 1.305 ± 0.644
5.222GluLeu: 5.222 ± 3.808
0.0GluMet: 0.0 ± 0.0
1.305GluAsn: 1.305 ± 1.885
3.916GluPro: 3.916 ± 1.933
1.305GluGln: 1.305 ± 2.109
2.611GluArg: 2.611 ± 1.288
5.222GluSer: 5.222 ± 4.017
3.916GluThr: 3.916 ± 3.425
3.916GluVal: 3.916 ± 1.933
1.305GluTrp: 1.305 ± 1.885
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
2.611PheCys: 2.611 ± 1.38
2.611PheAsp: 2.611 ± 1.708
1.305PheGlu: 1.305 ± 0.644
5.222PhePhe: 5.222 ± 2.577
1.305PheGly: 1.305 ± 2.109
1.305PheHis: 1.305 ± 0.644
2.611PheIle: 2.611 ± 1.708
2.611PheLys: 2.611 ± 1.708
3.916PheLeu: 3.916 ± 2.562
0.0PheMet: 0.0 ± 0.0
1.305PheAsn: 1.305 ± 0.644
1.305PhePro: 1.305 ± 0.644
0.0PheGln: 0.0 ± 0.0
3.916PheArg: 3.916 ± 1.263
2.611PheSer: 2.611 ± 1.708
1.305PheThr: 1.305 ± 0.644
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
3.916PheTyr: 3.916 ± 1.521
0.0PheXaa: 0.0 ± 0.0
Gly
2.611GlyAla: 2.611 ± 1.38
1.305GlyCys: 1.305 ± 2.109
7.833GlyAsp: 7.833 ± 2.526
5.222GlyGlu: 5.222 ± 3.587
0.0GlyPhe: 0.0 ± 0.0
14.36GlyGly: 14.36 ± 11.132
1.305GlyHis: 1.305 ± 0.644
3.916GlyIle: 3.916 ± 1.489
1.305GlyLys: 1.305 ± 0.644
1.305GlyLeu: 1.305 ± 2.109
3.916GlyMet: 3.916 ± 2.444
6.527GlyAsn: 6.527 ± 2.566
3.916GlyPro: 3.916 ± 2.156
0.0GlyGln: 0.0 ± 0.0
2.611GlyArg: 2.611 ± 1.708
6.527GlySer: 6.527 ± 4.995
1.305GlyThr: 1.305 ± 0.644
3.916GlyVal: 3.916 ± 2.562
2.611GlyTrp: 2.611 ± 1.288
2.611GlyTyr: 2.611 ± 1.288
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.305HisAsp: 1.305 ± 0.644
0.0HisGlu: 0.0 ± 0.0
2.611HisPhe: 2.611 ± 1.38
1.305HisGly: 1.305 ± 0.644
2.611HisHis: 2.611 ± 1.38
0.0HisIle: 0.0 ± 0.0
1.305HisLys: 1.305 ± 2.109
3.916HisLeu: 3.916 ± 2.562
0.0HisMet: 0.0 ± 0.0
2.611HisAsn: 2.611 ± 1.288
2.611HisPro: 2.611 ± 1.38
0.0HisGln: 0.0 ± 0.0
3.916HisArg: 3.916 ± 1.933
1.305HisSer: 1.305 ± 2.109
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
2.611HisTrp: 2.611 ± 1.288
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.305IleAla: 1.305 ± 0.644
1.305IleCys: 1.305 ± 2.109
2.611IleAsp: 2.611 ± 2.69
3.916IleGlu: 3.916 ± 3.846
2.611IlePhe: 2.611 ± 1.708
2.611IleGly: 2.611 ± 2.69
1.305IleHis: 1.305 ± 0.644
2.611IleIle: 2.611 ± 2.992
3.916IleLys: 3.916 ± 1.933
6.527IleLeu: 6.527 ± 1.818
0.0IleMet: 0.0 ± 0.0
2.611IleAsn: 2.611 ± 1.708
2.611IlePro: 2.611 ± 1.288
1.305IleGln: 1.305 ± 0.644
2.611IleArg: 2.611 ± 1.288
6.527IleSer: 6.527 ± 1.4
2.611IleThr: 2.611 ± 1.288
1.305IleVal: 1.305 ± 2.109
1.305IleTrp: 1.305 ± 0.644
2.611IleTyr: 2.611 ± 1.288
0.0IleXaa: 0.0 ± 0.0
Lys
1.305LysAla: 1.305 ± 0.644
0.0LysCys: 0.0 ± 0.0
1.305LysAsp: 1.305 ± 0.644
2.611LysGlu: 2.611 ± 1.587
1.305LysPhe: 1.305 ± 0.644
2.611LysGly: 2.611 ± 1.288
1.305LysHis: 1.305 ± 2.109
1.305LysIle: 1.305 ± 2.109
5.222LysLys: 5.222 ± 1.455
3.916LysLeu: 3.916 ± 1.933
1.305LysMet: 1.305 ± 1.223
0.0LysAsn: 0.0 ± 0.0
2.611LysPro: 2.611 ± 1.708
2.611LysGln: 2.611 ± 1.38
7.833LysArg: 7.833 ± 3.865
3.916LysSer: 3.916 ± 1.263
0.0LysThr: 0.0 ± 0.0
2.611LysVal: 2.611 ± 1.708
1.305LysTrp: 1.305 ± 0.644
5.222LysTyr: 5.222 ± 2.577
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
2.611LeuCys: 2.611 ± 3.106
6.527LeuAsp: 6.527 ± 3.221
3.916LeuGlu: 3.916 ± 1.521
5.222LeuPhe: 5.222 ± 3.416
2.611LeuGly: 2.611 ± 1.288
3.916LeuHis: 3.916 ± 2.562
6.527LeuIle: 6.527 ± 4.976
1.305LeuLys: 1.305 ± 2.109
11.749LeuLeu: 11.749 ± 0.175
2.611LeuMet: 2.611 ± 1.587
3.916LeuAsn: 3.916 ± 1.263
3.916LeuPro: 3.916 ± 2.562
5.222LeuGln: 5.222 ± 1.455
1.305LeuArg: 1.305 ± 0.644
5.222LeuSer: 5.222 ± 2.76
1.305LeuThr: 1.305 ± 0.644
5.222LeuVal: 5.222 ± 4.281
1.305LeuTrp: 1.305 ± 1.745
3.916LeuTyr: 3.916 ± 1.489
0.0LeuXaa: 0.0 ± 0.0
Met
1.305MetAla: 1.305 ± 0.644
1.305MetCys: 1.305 ± 1.745
3.916MetAsp: 3.916 ± 1.489
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
2.611MetGly: 2.611 ± 1.708
0.0MetHis: 0.0 ± 0.0
2.611MetIle: 2.611 ± 1.587
0.0MetLys: 0.0 ± 0.0
1.305MetLeu: 1.305 ± 0.644
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.305MetArg: 1.305 ± 1.885
1.305MetSer: 1.305 ± 1.885
1.305MetThr: 1.305 ± 0.644
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
2.611MetTyr: 2.611 ± 1.288
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.305AsnCys: 1.305 ± 0.644
1.305AsnAsp: 1.305 ± 0.644
1.305AsnGlu: 1.305 ± 0.644
2.611AsnPhe: 2.611 ± 1.38
0.0AsnGly: 0.0 ± 0.0
1.305AsnHis: 1.305 ± 1.745
1.305AsnIle: 1.305 ± 2.109
1.305AsnLys: 1.305 ± 0.644
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.611AsnPro: 2.611 ± 1.587
0.0AsnGln: 0.0 ± 0.0
7.833AsnArg: 7.833 ± 2.376
6.527AsnSer: 6.527 ± 1.581
1.305AsnThr: 1.305 ± 0.644
3.916AsnVal: 3.916 ± 1.933
1.305AsnTrp: 1.305 ± 0.644
2.611AsnTyr: 2.611 ± 1.288
0.0AsnXaa: 0.0 ± 0.0
Pro
1.305ProAla: 1.305 ± 0.644
1.305ProCys: 1.305 ± 0.644
1.305ProAsp: 1.305 ± 1.745
5.222ProGlu: 5.222 ± 3.175
2.611ProPhe: 2.611 ± 1.288
6.527ProGly: 6.527 ± 1.4
2.611ProHis: 2.611 ± 1.288
2.611ProIle: 2.611 ± 2.69
1.305ProLys: 1.305 ± 0.644
7.833ProLeu: 7.833 ± 3.311
0.0ProMet: 0.0 ± 0.0
2.611ProAsn: 2.611 ± 1.288
11.749ProPro: 11.749 ± 4.564
3.916ProGln: 3.916 ± 1.521
9.138ProArg: 9.138 ± 4.509
6.527ProSer: 6.527 ± 3.221
6.527ProThr: 6.527 ± 3.533
1.305ProVal: 1.305 ± 0.644
1.305ProTrp: 1.305 ± 0.644
3.916ProTyr: 3.916 ± 2.562
0.0ProXaa: 0.0 ± 0.0
Gln
1.305GlnAla: 1.305 ± 1.745
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.305GlnGlu: 1.305 ± 1.745
0.0GlnPhe: 0.0 ± 0.0
2.611GlnGly: 2.611 ± 1.288
1.305GlnHis: 1.305 ± 0.644
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
2.611GlnLeu: 2.611 ± 3.106
2.611GlnMet: 2.611 ± 2.156
1.305GlnAsn: 1.305 ± 0.644
7.833GlnPro: 7.833 ± 2.584
1.305GlnGln: 1.305 ± 0.644
1.305GlnArg: 1.305 ± 0.644
2.611GlnSer: 2.611 ± 1.288
1.305GlnThr: 1.305 ± 1.885
0.0GlnVal: 0.0 ± 0.0
1.305GlnTrp: 1.305 ± 2.109
1.305GlnTyr: 1.305 ± 1.745
0.0GlnXaa: 0.0 ± 0.0
Arg
2.611ArgAla: 2.611 ± 1.288
1.305ArgCys: 1.305 ± 0.644
2.611ArgAsp: 2.611 ± 1.38
6.527ArgGlu: 6.527 ± 3.541
1.305ArgPhe: 1.305 ± 0.644
3.916ArgGly: 3.916 ± 1.263
2.611ArgHis: 2.611 ± 1.288
6.527ArgIle: 6.527 ± 3.221
13.055ArgLys: 13.055 ± 3.125
1.305ArgLeu: 1.305 ± 0.644
3.916ArgMet: 3.916 ± 1.933
2.611ArgAsn: 2.611 ± 1.708
6.527ArgPro: 6.527 ± 3.221
1.305ArgGln: 1.305 ± 0.644
19.582ArgArg: 19.582 ± 9.663
6.527ArgSer: 6.527 ± 3.221
2.611ArgThr: 2.611 ± 1.288
3.916ArgVal: 3.916 ± 1.489
3.916ArgTrp: 3.916 ± 1.263
5.222ArgTyr: 5.222 ± 2.577
0.0ArgXaa: 0.0 ± 0.0
Ser
3.916SerAla: 3.916 ± 1.933
1.305SerCys: 1.305 ± 0.644
10.444SerAsp: 10.444 ± 2.578
5.222SerGlu: 5.222 ± 3.808
2.611SerPhe: 2.611 ± 1.38
5.222SerGly: 5.222 ± 4.281
1.305SerHis: 1.305 ± 2.109
3.916SerIle: 3.916 ± 1.933
1.305SerLys: 1.305 ± 0.644
9.138SerLeu: 9.138 ± 2.919
0.0SerMet: 0.0 ± 0.0
3.916SerAsn: 3.916 ± 1.933
6.527SerPro: 6.527 ± 3.042
3.916SerGln: 3.916 ± 2.156
3.916SerArg: 3.916 ± 1.521
11.749SerSer: 11.749 ± 4.264
5.222SerThr: 5.222 ± 3.175
3.916SerVal: 3.916 ± 1.933
2.611SerTrp: 2.611 ± 1.288
1.305SerTyr: 1.305 ± 1.885
0.0SerXaa: 0.0 ± 0.0
Thr
5.222ThrAla: 5.222 ± 2.577
1.305ThrCys: 1.305 ± 0.644
1.305ThrAsp: 1.305 ± 0.644
2.611ThrGlu: 2.611 ± 1.587
0.0ThrPhe: 0.0 ± 0.0
7.833ThrGly: 7.833 ± 4.723
1.305ThrHis: 1.305 ± 0.644
0.0ThrIle: 0.0 ± 0.0
0.0ThrLys: 0.0 ± 0.0
1.305ThrLeu: 1.305 ± 0.644
1.305ThrMet: 1.305 ± 1.715
1.305ThrAsn: 1.305 ± 1.885
6.527ThrPro: 6.527 ± 1.862
1.305ThrGln: 1.305 ± 1.885
3.916ThrArg: 3.916 ± 1.933
3.916ThrSer: 3.916 ± 3.425
1.305ThrThr: 1.305 ± 0.644
2.611ThrVal: 2.611 ± 1.288
1.305ThrTrp: 1.305 ± 0.644
2.611ThrTyr: 2.611 ± 1.288
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
3.916ValCys: 3.916 ± 1.933
0.0ValAsp: 0.0 ± 0.0
1.305ValGlu: 1.305 ± 0.644
1.305ValPhe: 1.305 ± 2.109
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
2.611ValIle: 2.611 ± 1.288
2.611ValLys: 2.611 ± 1.708
0.0ValLeu: 0.0 ± 0.0
0.0ValMet: 0.0 ± 0.0
2.611ValAsn: 2.611 ± 1.288
6.527ValPro: 6.527 ± 1.4
1.305ValGln: 1.305 ± 2.109
6.527ValArg: 6.527 ± 1.818
2.611ValSer: 2.611 ± 1.708
3.916ValThr: 3.916 ± 1.521
0.0ValVal: 0.0 ± 0.0
2.611ValTrp: 2.611 ± 1.708
2.611ValTyr: 2.611 ± 1.708
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
5.222TrpGlu: 5.222 ± 1.715
1.305TrpPhe: 1.305 ± 0.644
5.222TrpGly: 5.222 ± 1.715
1.305TrpHis: 1.305 ± 0.644
2.611TrpIle: 2.611 ± 1.288
2.611TrpLys: 2.611 ± 1.38
2.611TrpLeu: 2.611 ± 1.708
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.611TrpPro: 2.611 ± 3.106
0.0TrpGln: 0.0 ± 0.0
5.222TrpArg: 5.222 ± 2.577
1.305TrpSer: 1.305 ± 0.644
1.305TrpThr: 1.305 ± 0.644
1.305TrpVal: 1.305 ± 0.644
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
6.527TyrAsp: 6.527 ± 1.818
3.916TyrGlu: 3.916 ± 1.489
5.222TyrPhe: 5.222 ± 1.532
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
3.916TyrIle: 3.916 ± 1.933
5.222TyrLys: 5.222 ± 2.577
2.611TyrLeu: 2.611 ± 1.288
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.305TyrPro: 1.305 ± 0.644
1.305TyrGln: 1.305 ± 1.745
9.138TyrArg: 9.138 ± 1.61
0.0TyrSer: 0.0 ± 0.0
1.305TyrThr: 1.305 ± 0.644
1.305TyrVal: 1.305 ± 0.644
3.916TyrTrp: 3.916 ± 1.521
2.611TyrTyr: 2.611 ± 1.288
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (767 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski