Amino acid dipepetide frequency for Yoonia tamlensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.248AlaAla: 17.248 ± 0.211	1.159AlaCys: 1.159 ± 0.036	7.919AlaAsp: 7.919 ± 0.098	6.638AlaGlu: 6.638 ± 0.128	4.499AlaPhe: 4.499 ± 0.075	10.719AlaGly: 10.719 ± 0.107	2.427AlaHis: 2.427 ± 0.052	6.83AlaIle: 6.83 ± 0.089	4.405AlaLys: 4.405 ± 0.072	13.105AlaLeu: 13.105 ± 0.129	3.827AlaMet: 3.827 ± 0.061	3.282AlaAsn: 3.282 ± 0.056	5.778AlaPro: 5.778 ± 0.099	5.958AlaGln: 5.958 ± 0.1	7.921AlaArg: 7.921 ± 0.11	5.341AlaSer: 5.341 ± 0.071	6.67AlaThr: 6.67 ± 0.092	8.444AlaVal: 8.444 ± 0.098	1.371AlaTrp: 1.371 ± 0.041	2.617AlaTyr: 2.617 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.294CysAla: 1.294 ± 0.039	0.127CysCys: 0.127 ± 0.012	0.709CysAsp: 0.709 ± 0.026	0.454CysGlu: 0.454 ± 0.024	0.349CysPhe: 0.349 ± 0.021	0.974CysGly: 0.974 ± 0.033	0.262CysHis: 0.262 ± 0.015	0.472CysIle: 0.472 ± 0.024	0.251CysLys: 0.251 ± 0.018	0.872CysLeu: 0.872 ± 0.027	0.227CysMet: 0.227 ± 0.02	0.265CysAsn: 0.265 ± 0.016	0.486CysPro: 0.486 ± 0.022	0.254CysGln: 0.254 ± 0.017	0.427CysArg: 0.427 ± 0.022	0.418CysSer: 0.418 ± 0.02	0.476CysThr: 0.476 ± 0.02	0.666CysVal: 0.666 ± 0.025	0.113CysTrp: 0.113 ± 0.011	0.232CysTyr: 0.232 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	8.281AspAla: 8.281 ± 0.098	0.557AspCys: 0.557 ± 0.025	3.954AspAsp: 3.954 ± 0.082	3.226AspGlu: 3.226 ± 0.06	2.39AspPhe: 2.39 ± 0.049	5.69AspGly: 5.69 ± 0.086	1.538AspHis: 1.538 ± 0.042	3.698AspIle: 3.698 ± 0.06	1.759AspLys: 1.759 ± 0.049	6.302AspLeu: 6.302 ± 0.101	1.901AspMet: 1.901 ± 0.049	1.566AspAsn: 1.566 ± 0.041	3.591AspPro: 3.591 ± 0.065	2.226AspGln: 2.226 ± 0.042	3.859AspArg: 3.859 ± 0.061	2.341AspSer: 2.341 ± 0.056	3.176AspThr: 3.176 ± 0.058	4.549AspVal: 4.549 ± 0.073	1.167AspTrp: 1.167 ± 0.038	1.616AspTyr: 1.616 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	6.088GluAla: 6.088 ± 0.116	0.355GluCys: 0.355 ± 0.019	2.717GluAsp: 2.717 ± 0.058	2.682GluGlu: 2.682 ± 0.072	1.814GluPhe: 1.814 ± 0.042	3.642GluGly: 3.642 ± 0.064	1.015GluHis: 1.015 ± 0.031	3.749GluIle: 3.749 ± 0.065	2.032GluLys: 2.032 ± 0.056	4.639GluLeu: 4.639 ± 0.08	1.646GluMet: 1.646 ± 0.045	2.091GluAsn: 2.091 ± 0.049	1.983GluPro: 1.983 ± 0.041	1.835GluGln: 1.835 ± 0.05	3.048GluArg: 3.048 ± 0.067	1.988GluSer: 1.988 ± 0.043	3.7GluThr: 3.7 ± 0.066	3.601GluVal: 3.601 ± 0.058	0.581GluTrp: 0.581 ± 0.023	1.013GluTyr: 1.013 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.939PheAla: 4.939 ± 0.082	0.465PheCys: 0.465 ± 0.021	3.091PheAsp: 3.091 ± 0.059	2.184PheGlu: 2.184 ± 0.045	1.439PhePhe: 1.439 ± 0.046	3.948PheGly: 3.948 ± 0.076	0.775PheHis: 0.775 ± 0.027	1.932PheIle: 1.932 ± 0.043	1.005PheLys: 1.005 ± 0.039	3.369PheLeu: 3.369 ± 0.066	0.992PheMet: 0.992 ± 0.029	1.107PheAsn: 1.107 ± 0.041	1.506PhePro: 1.506 ± 0.043	1.124PheGln: 1.124 ± 0.032	1.924PheArg: 1.924 ± 0.048	2.055PheSer: 2.055 ± 0.046	2.23PheThr: 2.23 ± 0.043	2.878PheVal: 2.878 ± 0.056	0.602PheTrp: 0.602 ± 0.025	0.992PheTyr: 0.992 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	9.792GlyAla: 9.792 ± 0.12	0.836GlyCys: 0.836 ± 0.029	4.937GlyAsp: 4.937 ± 0.072	3.989GlyGlu: 3.989 ± 0.068	3.844GlyPhe: 3.844 ± 0.07	6.978GlyGly: 6.978 ± 0.107	1.868GlyHis: 1.868 ± 0.051	4.796GlyIle: 4.796 ± 0.075	3.25GlyLys: 3.25 ± 0.069	8.499GlyLeu: 8.499 ± 0.103	2.543GlyMet: 2.543 ± 0.051	2.335GlyAsn: 2.335 ± 0.058	3.447GlyPro: 3.447 ± 0.066	3.297GlyGln: 3.297 ± 0.053	5.062GlyArg: 5.062 ± 0.076	3.956GlySer: 3.956 ± 0.067	4.697GlyThr: 4.697 ± 0.076	6.419GlyVal: 6.419 ± 0.095	1.36GlyTrp: 1.36 ± 0.036	2.433GlyTyr: 2.433 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.516HisAla: 2.516 ± 0.053	0.244HisCys: 0.244 ± 0.018	1.332HisAsp: 1.332 ± 0.048	0.98HisGlu: 0.98 ± 0.028	0.895HisPhe: 0.895 ± 0.032	1.779HisGly: 1.779 ± 0.043	0.544HisHis: 0.544 ± 0.033	1.156HisIle: 1.156 ± 0.034	0.6HisLys: 0.6 ± 0.025	2.091HisLeu: 2.091 ± 0.047	0.625HisMet: 0.625 ± 0.027	0.529HisAsn: 0.529 ± 0.023	1.272HisPro: 1.272 ± 0.041	0.647HisGln: 0.647 ± 0.025	1.258HisArg: 1.258 ± 0.041	0.888HisSer: 0.888 ± 0.032	0.858HisThr: 0.858 ± 0.029	1.56HisVal: 1.56 ± 0.037	0.356HisTrp: 0.356 ± 0.02	0.612HisTyr: 0.612 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	8.656IleAla: 8.656 ± 0.094	0.761IleCys: 0.761 ± 0.031	4.003IleAsp: 4.003 ± 0.068	3.123IleGlu: 3.123 ± 0.062	1.916IlePhe: 1.916 ± 0.05	5.366IleGly: 5.366 ± 0.091	0.949IleHis: 0.949 ± 0.03	2.961IleIle: 2.961 ± 0.074	1.851IleLys: 1.851 ± 0.047	4.902IleLeu: 4.902 ± 0.079	1.353IleMet: 1.353 ± 0.041	1.703IleAsn: 1.703 ± 0.044	2.526IlePro: 2.526 ± 0.051	1.2IleGln: 1.2 ± 0.035	2.955IleArg: 2.955 ± 0.06	3.276IleSer: 3.276 ± 0.06	3.598IleThr: 3.598 ± 0.061	4.223IleVal: 4.223 ± 0.077	0.851IleTrp: 0.851 ± 0.031	1.433IleTyr: 1.433 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	3.912LysAla: 3.912 ± 0.082	0.179LysCys: 0.179 ± 0.015	1.887LysAsp: 1.887 ± 0.052	1.411LysGlu: 1.411 ± 0.041	1.04LysPhe: 1.04 ± 0.033	2.628LysGly: 2.628 ± 0.059	0.764LysHis: 0.764 ± 0.028	1.993LysIle: 1.993 ± 0.046	1.325LysLys: 1.325 ± 0.04	3.093LysLeu: 3.093 ± 0.06	1.024LysMet: 1.024 ± 0.031	1.027LysAsn: 1.027 ± 0.031	1.894LysPro: 1.894 ± 0.053	1.078LysGln: 1.078 ± 0.031	2.249LysArg: 2.249 ± 0.053	2.192LysSer: 2.192 ± 0.05	2.097LysThr: 2.097 ± 0.048	2.257LysVal: 2.257 ± 0.05	0.434LysTrp: 0.434 ± 0.021	0.712LysTyr: 0.712 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	12.209LeuAla: 12.209 ± 0.121	1.036LeuCys: 1.036 ± 0.031	6.007LeuAsp: 6.007 ± 0.091	4.516LeuGlu: 4.516 ± 0.074	3.524LeuPhe: 3.524 ± 0.064	8.217LeuGly: 8.217 ± 0.098	1.943LeuHis: 1.943 ± 0.046	5.503LeuIle: 5.503 ± 0.084	2.98LeuLys: 2.98 ± 0.055	8.423LeuLeu: 8.423 ± 0.121	2.577LeuMet: 2.577 ± 0.056	2.858LeuAsn: 2.858 ± 0.054	5.054LeuPro: 5.054 ± 0.073	3.068LeuGln: 3.068 ± 0.06	6.79LeuArg: 6.79 ± 0.099	5.999LeuSer: 5.999 ± 0.083	6.166LeuThr: 6.166 ± 0.073	6.665LeuVal: 6.665 ± 0.089	1.242LeuTrp: 1.242 ± 0.043	1.872LeuTyr: 1.872 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.348MetAla: 3.348 ± 0.058	0.207MetCys: 0.207 ± 0.014	1.481MetAsp: 1.481 ± 0.039	1.166MetGlu: 1.166 ± 0.03	0.91MetPhe: 0.91 ± 0.038	2.344MetGly: 2.344 ± 0.049	0.578MetHis: 0.578 ± 0.021	1.863MetIle: 1.863 ± 0.047	1.108MetLys: 1.108 ± 0.036	2.667MetLeu: 2.667 ± 0.053	0.796MetMet: 0.796 ± 0.032	0.979MetAsn: 0.979 ± 0.029	1.568MetPro: 1.568 ± 0.038	1.152MetGln: 1.152 ± 0.036	1.948MetArg: 1.948 ± 0.042	1.654MetSer: 1.654 ± 0.047	2.239MetThr: 2.239 ± 0.052	2.027MetVal: 2.027 ± 0.049	0.247MetTrp: 0.247 ± 0.016	0.392MetTyr: 0.392 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.784AsnAla: 3.784 ± 0.064	0.314AsnCys: 0.314 ± 0.017	1.749AsnAsp: 1.749 ± 0.04	1.212AsnGlu: 1.212 ± 0.036	1.092AsnPhe: 1.092 ± 0.033	2.85AsnGly: 2.85 ± 0.066	0.591AsnHis: 0.591 ± 0.025	1.781AsnIle: 1.781 ± 0.051	0.806AsnLys: 0.806 ± 0.033	2.795AsnLeu: 2.795 ± 0.051	0.819AsnMet: 0.819 ± 0.032	0.845AsnAsn: 0.845 ± 0.029	2.04AsnPro: 2.04 ± 0.039	0.831AsnGln: 0.831 ± 0.031	1.768AsnArg: 1.768 ± 0.043	1.304AsnSer: 1.304 ± 0.038	1.602AsnThr: 1.602 ± 0.047	2.011AsnVal: 2.011 ± 0.05	0.478AsnTrp: 0.478 ± 0.023	0.791AsnTyr: 0.791 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	6.07ProAla: 6.07 ± 0.088	0.364ProCys: 0.364 ± 0.021	3.86ProAsp: 3.86 ± 0.066	3.213ProGlu: 3.213 ± 0.062	1.99ProPhe: 1.99 ± 0.05	3.356ProGly: 3.356 ± 0.065	1.077ProHis: 1.077 ± 0.037	2.419ProIle: 2.419 ± 0.049	1.776ProLys: 1.776 ± 0.05	4.552ProLeu: 4.552 ± 0.075	1.297ProMet: 1.297 ± 0.039	1.45ProAsn: 1.45 ± 0.041	1.967ProPro: 1.967 ± 0.057	1.937ProGln: 1.937 ± 0.047	2.439ProArg: 2.439 ± 0.05	2.37ProSer: 2.37 ± 0.047	2.587ProThr: 2.587 ± 0.059	4.165ProVal: 4.165 ± 0.063	0.584ProTrp: 0.584 ± 0.026	1.129ProTyr: 1.129 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.387GlnAla: 4.387 ± 0.078	0.246GlnCys: 0.246 ± 0.016	1.85GlnAsp: 1.85 ± 0.047	1.634GlnGlu: 1.634 ± 0.047	1.331GlnPhe: 1.331 ± 0.037	2.703GlnGly: 2.703 ± 0.055	0.642GlnHis: 0.642 ± 0.027	2.508GlnIle: 2.508 ± 0.05	1.172GlnLys: 1.172 ± 0.04	3.381GlnLeu: 3.381 ± 0.069	1.28GlnMet: 1.28 ± 0.032	1.14GlnAsn: 1.14 ± 0.035	1.646GlnPro: 1.646 ± 0.04	1.18GlnGln: 1.18 ± 0.036	2.192GlnArg: 2.192 ± 0.049	2.174GlnSer: 2.174 ± 0.049	2.439GlnThr: 2.439 ± 0.051	2.535GlnVal: 2.535 ± 0.052	0.433GlnTrp: 0.433 ± 0.021	0.665GlnTyr: 0.665 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.643ArgAla: 7.643 ± 0.101	0.445ArgCys: 0.445 ± 0.022	4.007ArgAsp: 4.007 ± 0.063	3.024ArgGlu: 3.024 ± 0.059	2.494ArgPhe: 2.494 ± 0.054	4.129ArgGly: 4.129 ± 0.058	1.327ArgHis: 1.327 ± 0.036	3.71ArgIle: 3.71 ± 0.069	2.264ArgLys: 2.264 ± 0.053	6.128ArgLeu: 6.128 ± 0.089	1.9ArgMet: 1.9 ± 0.047	1.894ArgAsn: 1.894 ± 0.049	2.81ArgPro: 2.81 ± 0.057	2.107ArgGln: 2.107 ± 0.055	3.987ArgArg: 3.987 ± 0.076	2.899ArgSer: 2.899 ± 0.054	2.779ArgThr: 2.779 ± 0.057	4.172ArgVal: 4.172 ± 0.077	0.821ArgTrp: 0.821 ± 0.034	1.487ArgTyr: 1.487 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	5.797SerAla: 5.797 ± 0.082	0.474SerCys: 0.474 ± 0.022	3.35SerAsp: 3.35 ± 0.062	2.625SerGlu: 2.625 ± 0.052	2.205SerPhe: 2.205 ± 0.05	5.08SerGly: 5.08 ± 0.077	1.049SerHis: 1.049 ± 0.035	2.565SerIle: 2.565 ± 0.06	1.64SerLys: 1.64 ± 0.038	4.836SerLeu: 4.836 ± 0.067	1.337SerMet: 1.337 ± 0.041	1.572SerAsn: 1.572 ± 0.045	2.388SerPro: 2.388 ± 0.045	1.697SerGln: 1.697 ± 0.042	2.741SerArg: 2.741 ± 0.059	2.35SerSer: 2.35 ± 0.06	2.587SerThr: 2.587 ± 0.052	3.673SerVal: 3.673 ± 0.062	0.648SerTrp: 0.648 ± 0.027	1.392SerTyr: 1.392 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.858ThrAla: 6.858 ± 0.094	0.54ThrCys: 0.54 ± 0.027	3.533ThrAsp: 3.533 ± 0.06	2.624ThrGlu: 2.624 ± 0.058	2.225ThrPhe: 2.225 ± 0.053	5.382ThrGly: 5.382 ± 0.075	1.242ThrHis: 1.242 ± 0.035	3.21ThrIle: 3.21 ± 0.063	1.707ThrLys: 1.707 ± 0.047	6.061ThrLeu: 6.061 ± 0.083	1.476ThrMet: 1.476 ± 0.038	1.533ThrAsn: 1.533 ± 0.042	3.561ThrPro: 3.561 ± 0.064	2.128ThrGln: 2.128 ± 0.051	3.38ThrArg: 3.38 ± 0.062	2.837ThrSer: 2.837 ± 0.064	3.19ThrThr: 3.19 ± 0.065	4.469ThrVal: 4.469 ± 0.083	0.65ThrTrp: 0.65 ± 0.023	1.528ThrTyr: 1.528 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	9.106ValAla: 9.106 ± 0.098	0.618ValCys: 0.618 ± 0.024	4.358ValAsp: 4.358 ± 0.056	3.659ValGlu: 3.659 ± 0.075	3.018ValPhe: 3.018 ± 0.062	5.449ValGly: 5.449 ± 0.081	1.293ValHis: 1.293 ± 0.042	4.685ValIle: 4.685 ± 0.072	2.219ValLys: 2.219 ± 0.061	7.084ValLeu: 7.084 ± 0.09	2.138ValMet: 2.138 ± 0.049	2.185ValAsn: 2.185 ± 0.052	3.315ValPro: 3.315 ± 0.057	2.45ValGln: 2.45 ± 0.047	3.703ValArg: 3.703 ± 0.067	4.167ValSer: 4.167 ± 0.067	5.077ValThr: 5.077 ± 0.065	5.633ValVal: 5.633 ± 0.083	0.918ValTrp: 0.918 ± 0.033	1.496ValTyr: 1.496 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.453TrpAla: 1.453 ± 0.043	0.139TrpCys: 0.139 ± 0.013	0.887TrpAsp: 0.887 ± 0.028	0.626TrpGlu: 0.626 ± 0.026	0.568TrpPhe: 0.568 ± 0.024	0.973TrpGly: 0.973 ± 0.038	0.328TrpHis: 0.328 ± 0.017	0.691TrpIle: 0.691 ± 0.026	0.431TrpLys: 0.431 ± 0.02	1.475TrpLeu: 1.475 ± 0.042	0.383TrpMet: 0.383 ± 0.018	0.436TrpAsn: 0.436 ± 0.024	0.648TrpPro: 0.648 ± 0.025	0.598TrpGln: 0.598 ± 0.025	0.96TrpArg: 0.96 ± 0.03	0.693TrpSer: 0.693 ± 0.025	0.716TrpThr: 0.716 ± 0.025	0.946TrpVal: 0.946 ± 0.034	0.211TrpTrp: 0.211 ± 0.013	0.281TrpTyr: 0.281 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.779TyrAla: 2.779 ± 0.052	0.262TyrCys: 0.262 ± 0.016	1.758TyrAsp: 1.758 ± 0.049	1.233TyrGlu: 1.233 ± 0.041	1.015TyrPhe: 1.015 ± 0.035	2.132TyrGly: 2.132 ± 0.04	0.528TyrHis: 0.528 ± 0.024	1.083TyrIle: 1.083 ± 0.035	0.614TyrLys: 0.614 ± 0.025	2.375TyrLeu: 2.375 ± 0.055	0.534TyrMet: 0.534 ± 0.023	0.666TyrAsn: 0.666 ± 0.031	1.121TyrPro: 1.121 ± 0.036	0.776TyrGln: 0.776 ± 0.031	1.416TyrArg: 1.416 ± 0.046	1.104TyrSer: 1.104 ± 0.035	1.246TyrThr: 1.246 ± 0.038	1.679TyrVal: 1.679 ± 0.039	0.376TyrTrp: 0.376 ± 0.02	0.662TyrTyr: 0.662 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3187 proteins (974354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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