Amino acid dipepetide frequency for Mucilaginibacter ginsenosidivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.847AlaAla: 6.847 ± 0.083	0.791AlaCys: 0.791 ± 0.021	4.901AlaAsp: 4.901 ± 0.061	4.453AlaGlu: 4.453 ± 0.063	3.653AlaPhe: 3.653 ± 0.047	6.304AlaGly: 6.304 ± 0.071	1.359AlaHis: 1.359 ± 0.033	5.637AlaIle: 5.637 ± 0.075	4.78AlaLys: 4.78 ± 0.058	7.08AlaLeu: 7.08 ± 0.075	1.826AlaMet: 1.826 ± 0.036	3.6AlaAsn: 3.6 ± 0.047	2.53AlaPro: 2.53 ± 0.051	2.822AlaGln: 2.822 ± 0.045	2.801AlaArg: 2.801 ± 0.049	4.543AlaSer: 4.543 ± 0.064	4.185AlaThr: 4.185 ± 0.073	5.047AlaVal: 5.047 ± 0.071	0.899AlaTrp: 0.899 ± 0.025	2.895AlaTyr: 2.895 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.588CysAla: 0.588 ± 0.021	0.146CysCys: 0.146 ± 0.01	0.442CysAsp: 0.442 ± 0.018	0.404CysGlu: 0.404 ± 0.017	0.469CysPhe: 0.469 ± 0.019	0.704CysGly: 0.704 ± 0.023	0.215CysHis: 0.215 ± 0.012	0.625CysIle: 0.625 ± 0.018	0.514CysLys: 0.514 ± 0.02	0.85CysLeu: 0.85 ± 0.024	0.194CysMet: 0.194 ± 0.011	0.388CysAsn: 0.388 ± 0.014	0.375CysPro: 0.375 ± 0.015	0.241CysGln: 0.241 ± 0.013	0.395CysArg: 0.395 ± 0.017	0.565CysSer: 0.565 ± 0.023	0.465CysThr: 0.465 ± 0.02	0.514CysVal: 0.514 ± 0.016	0.092CysTrp: 0.092 ± 0.007	0.377CysTyr: 0.377 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.134AspAla: 4.134 ± 0.059	0.428AspCys: 0.428 ± 0.017	3.016AspAsp: 3.016 ± 0.051	3.533AspGlu: 3.533 ± 0.05	3.122AspPhe: 3.122 ± 0.046	4.08AspGly: 4.08 ± 0.074	1.245AspHis: 1.245 ± 0.03	4.206AspIle: 4.206 ± 0.061	4.042AspLys: 4.042 ± 0.047	4.959AspLeu: 4.959 ± 0.069	1.355AspMet: 1.355 ± 0.029	2.934AspAsn: 2.934 ± 0.044	2.392AspPro: 2.392 ± 0.04	1.831AspGln: 1.831 ± 0.037	2.192AspArg: 2.192 ± 0.037	3.072AspSer: 3.072 ± 0.047	2.952AspThr: 2.952 ± 0.048	3.428AspVal: 3.428 ± 0.043	0.819AspTrp: 0.819 ± 0.025	2.589AspTyr: 2.589 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	4.004GluAla: 4.004 ± 0.062	0.35GluCys: 0.35 ± 0.017	2.592GluAsp: 2.592 ± 0.044	3.18GluGlu: 3.18 ± 0.063	2.323GluPhe: 2.323 ± 0.042	3.192GluGly: 3.192 ± 0.045	1.148GluHis: 1.148 ± 0.029	3.901GluIle: 3.901 ± 0.055	4.493GluLys: 4.493 ± 0.066	5.523GluLeu: 5.523 ± 0.072	1.446GluMet: 1.446 ± 0.032	2.954GluAsn: 2.954 ± 0.047	1.792GluPro: 1.792 ± 0.04	2.372GluGln: 2.372 ± 0.049	2.533GluArg: 2.533 ± 0.049	2.653GluSer: 2.653 ± 0.045	2.836GluThr: 2.836 ± 0.048	3.388GluVal: 3.388 ± 0.047	0.657GluTrp: 0.657 ± 0.026	2.058GluTyr: 2.058 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.588PheAla: 3.588 ± 0.052	0.49PheCys: 0.49 ± 0.02	3.035PheAsp: 3.035 ± 0.044	2.562PheGlu: 2.562 ± 0.041	2.51PhePhe: 2.51 ± 0.05	3.488PheGly: 3.488 ± 0.05	0.915PheHis: 0.915 ± 0.024	3.577PheIle: 3.577 ± 0.058	3.245PheLys: 3.245 ± 0.044	4.232PheLeu: 4.232 ± 0.062	1.126PheMet: 1.126 ± 0.027	2.786PheAsn: 2.786 ± 0.044	1.744PhePro: 1.744 ± 0.032	1.306PheGln: 1.306 ± 0.029	1.907PheArg: 1.907 ± 0.034	3.539PheSer: 3.539 ± 0.051	3.136PheThr: 3.136 ± 0.052	2.934PheVal: 2.934 ± 0.053	0.607PheTrp: 0.607 ± 0.021	2.116PheTyr: 2.116 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.843GlyAla: 4.843 ± 0.072	0.687GlyCys: 0.687 ± 0.026	3.758GlyAsp: 3.758 ± 0.052	3.362GlyGlu: 3.362 ± 0.046	3.724GlyPhe: 3.724 ± 0.06	5.129GlyGly: 5.129 ± 0.082	1.461GlyHis: 1.461 ± 0.034	5.378GlyIle: 5.378 ± 0.067	5.421GlyLys: 5.421 ± 0.067	6.551GlyLeu: 6.551 ± 0.067	1.752GlyMet: 1.752 ± 0.035	3.82GlyAsn: 3.82 ± 0.061	1.941GlyPro: 1.941 ± 0.04	2.309GlyGln: 2.309 ± 0.049	2.805GlyArg: 2.805 ± 0.044	4.518GlySer: 4.518 ± 0.072	4.395GlyThr: 4.395 ± 0.082	4.519GlyVal: 4.519 ± 0.047	1.027GlyTrp: 1.027 ± 0.031	3.19GlyTyr: 3.19 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.31HisAla: 1.31 ± 0.032	0.212HisCys: 0.212 ± 0.011	1.09HisAsp: 1.09 ± 0.027	1.052HisGlu: 1.052 ± 0.027	1.196HisPhe: 1.196 ± 0.029	1.307HisGly: 1.307 ± 0.03	0.598HisHis: 0.598 ± 0.019	1.526HisIle: 1.526 ± 0.033	1.108HisLys: 1.108 ± 0.027	2.004HisLeu: 2.004 ± 0.037	0.414HisMet: 0.414 ± 0.017	1.026HisAsn: 1.026 ± 0.027	1.084HisPro: 1.084 ± 0.027	0.785HisGln: 0.785 ± 0.02	0.829HisArg: 0.829 ± 0.022	1.104HisSer: 1.104 ± 0.027	1.077HisThr: 1.077 ± 0.029	1.139HisVal: 1.139 ± 0.029	0.307HisTrp: 0.307 ± 0.013	0.967HisTyr: 0.967 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.063IleAla: 6.063 ± 0.071	0.719IleCys: 0.719 ± 0.025	4.278IleAsp: 4.278 ± 0.058	3.849IleGlu: 3.849 ± 0.061	3.173IlePhe: 3.173 ± 0.052	4.959IleGly: 4.959 ± 0.069	1.313IleHis: 1.313 ± 0.031	5.033IleIle: 5.033 ± 0.071	4.839IleLys: 4.839 ± 0.064	6.015IleLeu: 6.015 ± 0.08	1.415IleMet: 1.415 ± 0.032	4.055IleAsn: 4.055 ± 0.051	3.071IlePro: 3.071 ± 0.047	2.091IleGln: 2.091 ± 0.04	3.172IleArg: 3.172 ± 0.053	4.964IleSer: 4.964 ± 0.06	4.682IleThr: 4.682 ± 0.058	4.444IleVal: 4.444 ± 0.061	0.733IleTrp: 0.733 ± 0.025	2.7IleTyr: 2.7 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	5.307LysAla: 5.307 ± 0.071	0.369LysCys: 0.369 ± 0.016	4.137LysAsp: 4.137 ± 0.059	4.131LysGlu: 4.131 ± 0.061	2.616LysPhe: 2.616 ± 0.042	4.552LysGly: 4.552 ± 0.06	1.34LysHis: 1.34 ± 0.033	4.747LysIle: 4.747 ± 0.057	5.341LysLys: 5.341 ± 0.072	6.15LysLeu: 6.15 ± 0.07	1.901LysMet: 1.901 ± 0.035	3.973LysAsn: 3.973 ± 0.055	2.868LysPro: 2.868 ± 0.046	2.823LysGln: 2.823 ± 0.049	2.814LysArg: 2.814 ± 0.042	3.693LysSer: 3.693 ± 0.051	4.151LysThr: 4.151 ± 0.052	4.409LysVal: 4.409 ± 0.06	0.803LysTrp: 0.803 ± 0.024	2.892LysTyr: 2.892 ± 0.042	0.0LysXaa: 0.0 ± 0.0
Leu	7.181LeuAla: 7.181 ± 0.076	0.824LeuCys: 0.824 ± 0.025	4.821LeuAsp: 4.821 ± 0.062	4.43LeuGlu: 4.43 ± 0.069	4.658LeuPhe: 4.658 ± 0.065	5.793LeuGly: 5.793 ± 0.066	1.843LeuHis: 1.843 ± 0.037	6.358LeuIle: 6.358 ± 0.079	7.003LeuLys: 7.003 ± 0.078	9.339LeuLeu: 9.339 ± 0.123	2.24LeuMet: 2.24 ± 0.041	5.143LeuAsn: 5.143 ± 0.06	4.091LeuPro: 4.091 ± 0.057	3.547LeuGln: 3.547 ± 0.053	3.759LeuArg: 3.759 ± 0.053	6.584LeuSer: 6.584 ± 0.062	5.438LeuThr: 5.438 ± 0.06	5.901LeuVal: 5.901 ± 0.077	0.962LeuTrp: 0.962 ± 0.03	3.377LeuTyr: 3.377 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	1.999MetAla: 1.999 ± 0.036	0.153MetCys: 0.153 ± 0.01	1.295MetAsp: 1.295 ± 0.028	1.306MetGlu: 1.306 ± 0.033	0.849MetPhe: 0.849 ± 0.024	1.6MetGly: 1.6 ± 0.031	0.5MetHis: 0.5 ± 0.019	1.576MetIle: 1.576 ± 0.038	2.05MetLys: 2.05 ± 0.033	2.2MetLeu: 2.2 ± 0.04	0.649MetMet: 0.649 ± 0.021	1.241MetAsn: 1.241 ± 0.026	1.141MetPro: 1.141 ± 0.028	0.938MetGln: 0.938 ± 0.024	1.064MetArg: 1.064 ± 0.027	1.393MetSer: 1.393 ± 0.032	1.242MetThr: 1.242 ± 0.028	1.503MetVal: 1.503 ± 0.031	0.186MetTrp: 0.186 ± 0.012	0.644MetTyr: 0.644 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.843AsnAla: 3.843 ± 0.053	0.46AsnCys: 0.46 ± 0.018	2.938AsnAsp: 2.938 ± 0.05	2.719AsnGlu: 2.719 ± 0.042	2.56AsnPhe: 2.56 ± 0.044	4.095AsnGly: 4.095 ± 0.069	1.011AsnHis: 1.011 ± 0.025	4.035AsnIle: 4.035 ± 0.059	3.409AsnLys: 3.409 ± 0.051	4.637AsnLeu: 4.637 ± 0.059	1.228AsnMet: 1.228 ± 0.023	3.065AsnAsn: 3.065 ± 0.056	2.62AsnPro: 2.62 ± 0.043	1.825AsnGln: 1.825 ± 0.037	2.235AsnArg: 2.235 ± 0.041	3.19AsnSer: 3.19 ± 0.055	3.164AsnThr: 3.164 ± 0.045	3.133AsnVal: 3.133 ± 0.049	0.707AsnTrp: 0.707 ± 0.024	2.553AsnTyr: 2.553 ± 0.039	0.0AsnXaa: 0.0 ± 0.0
Pro	3.691ProAla: 3.691 ± 0.057	0.242ProCys: 0.242 ± 0.011	2.874ProAsp: 2.874 ± 0.048	2.759ProGlu: 2.759 ± 0.045	1.948ProPhe: 1.948 ± 0.035	3.37ProGly: 3.37 ± 0.061	0.749ProHis: 0.749 ± 0.021	2.279ProIle: 2.279 ± 0.044	2.249ProLys: 2.249 ± 0.038	3.392ProLeu: 3.392 ± 0.053	0.809ProMet: 0.809 ± 0.025	1.936ProAsn: 1.936 ± 0.037	1.335ProPro: 1.335 ± 0.037	1.435ProGln: 1.435 ± 0.035	1.177ProArg: 1.177 ± 0.032	2.162ProSer: 2.162 ± 0.043	1.863ProThr: 1.863 ± 0.041	3.537ProVal: 3.537 ± 0.06	0.447ProTrp: 0.447 ± 0.017	1.63ProTyr: 1.63 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.679GlnAla: 2.679 ± 0.049	0.231GlnCys: 0.231 ± 0.013	1.577GlnAsp: 1.577 ± 0.032	1.724GlnGlu: 1.724 ± 0.037	1.689GlnPhe: 1.689 ± 0.035	2.048GlnGly: 2.048 ± 0.036	0.807GlnHis: 0.807 ± 0.023	2.213GlnIle: 2.213 ± 0.043	2.655GlnLys: 2.655 ± 0.045	3.833GlnLeu: 3.833 ± 0.059	0.939GlnMet: 0.939 ± 0.027	1.924GlnAsn: 1.924 ± 0.042	1.564GlnPro: 1.564 ± 0.04	1.94GlnGln: 1.94 ± 0.05	1.485GlnArg: 1.485 ± 0.033	2.149GlnSer: 2.149 ± 0.036	2.041GlnThr: 2.041 ± 0.036	2.458GlnVal: 2.458 ± 0.042	0.426GlnTrp: 0.426 ± 0.018	1.533GlnTyr: 1.533 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	2.622ArgAla: 2.622 ± 0.047	0.246ArgCys: 0.246 ± 0.013	2.293ArgAsp: 2.293 ± 0.041	2.385ArgGlu: 2.385 ± 0.047	2.055ArgPhe: 2.055 ± 0.036	2.287ArgGly: 2.287 ± 0.037	0.856ArgHis: 0.856 ± 0.024	3.124ArgIle: 3.124 ± 0.051	3.006ArgLys: 3.006 ± 0.05	4.017ArgLeu: 4.017 ± 0.057	1.081ArgMet: 1.081 ± 0.027	2.14ArgAsn: 2.14 ± 0.035	1.498ArgPro: 1.498 ± 0.034	1.621ArgGln: 1.621 ± 0.034	1.819ArgArg: 1.819 ± 0.042	2.524ArgSer: 2.524 ± 0.042	2.095ArgThr: 2.095 ± 0.034	2.525ArgVal: 2.525 ± 0.037	0.523ArgTrp: 0.523 ± 0.021	1.851ArgTyr: 1.851 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	4.954SerAla: 4.954 ± 0.065	0.61SerCys: 0.61 ± 0.018	3.21SerAsp: 3.21 ± 0.044	2.93SerGlu: 2.93 ± 0.047	3.386SerPhe: 3.386 ± 0.053	5.145SerGly: 5.145 ± 0.069	1.145SerHis: 1.145 ± 0.03	4.423SerIle: 4.423 ± 0.064	3.744SerLys: 3.744 ± 0.056	6.012SerLeu: 6.012 ± 0.063	1.342SerMet: 1.342 ± 0.029	2.98SerAsn: 2.98 ± 0.048	2.51SerPro: 2.51 ± 0.039	1.954SerGln: 1.954 ± 0.032	2.495SerArg: 2.495 ± 0.042	3.858SerSer: 3.858 ± 0.058	3.464SerThr: 3.464 ± 0.067	4.315SerVal: 4.315 ± 0.053	0.758SerTrp: 0.758 ± 0.021	2.615SerTyr: 2.615 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	4.761ThrAla: 4.761 ± 0.066	0.465ThrCys: 0.465 ± 0.017	3.423ThrAsp: 3.423 ± 0.048	2.835ThrGlu: 2.835 ± 0.048	2.809ThrPhe: 2.809 ± 0.049	5.194ThrGly: 5.194 ± 0.087	1.117ThrHis: 1.117 ± 0.025	4.477ThrIle: 4.477 ± 0.062	2.959ThrLys: 2.959 ± 0.05	5.248ThrLeu: 5.248 ± 0.062	1.093ThrMet: 1.093 ± 0.027	2.813ThrAsn: 2.813 ± 0.054	2.642ThrPro: 2.642 ± 0.046	1.846ThrGln: 1.846 ± 0.037	2.093ThrArg: 2.093 ± 0.034	3.53ThrSer: 3.53 ± 0.058	3.519ThrThr: 3.519 ± 0.082	4.105ThrVal: 4.105 ± 0.063	0.688ThrTrp: 0.688 ± 0.019	2.386ThrTyr: 2.386 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	4.823ValAla: 4.823 ± 0.056	0.629ValCys: 0.629 ± 0.021	3.504ValAsp: 3.504 ± 0.047	3.273ValGlu: 3.273 ± 0.056	3.233ValPhe: 3.233 ± 0.05	3.744ValGly: 3.744 ± 0.06	1.168ValHis: 1.168 ± 0.028	5.035ValIle: 5.035 ± 0.061	4.639ValLys: 4.639 ± 0.052	6.097ValLeu: 6.097 ± 0.076	1.583ValMet: 1.583 ± 0.032	3.654ValAsn: 3.654 ± 0.051	2.524ValPro: 2.524 ± 0.039	1.991ValGln: 1.991 ± 0.042	2.467ValArg: 2.467 ± 0.036	4.505ValSer: 4.505 ± 0.052	4.169ValThr: 4.169 ± 0.065	4.285ValVal: 4.285 ± 0.061	0.703ValTrp: 0.703 ± 0.024	2.614ValTyr: 2.614 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.849TrpAla: 0.849 ± 0.025	0.121TrpCys: 0.121 ± 0.008	0.691TrpAsp: 0.691 ± 0.019	0.624TrpGlu: 0.624 ± 0.022	0.624TrpPhe: 0.624 ± 0.022	0.853TrpGly: 0.853 ± 0.029	0.315TrpHis: 0.315 ± 0.015	0.779TrpIle: 0.779 ± 0.028	0.825TrpLys: 0.825 ± 0.027	1.223TrpLeu: 1.223 ± 0.034	0.355TrpMet: 0.355 ± 0.016	0.637TrpAsn: 0.637 ± 0.022	0.39TrpPro: 0.39 ± 0.015	0.563TrpGln: 0.563 ± 0.021	0.535TrpArg: 0.535 ± 0.017	0.633TrpSer: 0.633 ± 0.024	0.619TrpThr: 0.619 ± 0.02	0.747TrpVal: 0.747 ± 0.024	0.232TrpTrp: 0.232 ± 0.01	0.488TrpTyr: 0.488 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.866TyrAla: 2.866 ± 0.044	0.39TyrCys: 0.39 ± 0.014	2.453TyrAsp: 2.453 ± 0.04	1.882TyrGlu: 1.882 ± 0.038	2.248TyrPhe: 2.248 ± 0.037	2.747TyrGly: 2.747 ± 0.04	1.03TyrHis: 1.03 ± 0.025	2.64TyrIle: 2.64 ± 0.039	2.695TyrLys: 2.695 ± 0.043	3.933TyrLeu: 3.933 ± 0.047	0.781TyrMet: 0.781 ± 0.023	2.356TyrAsn: 2.356 ± 0.043	1.77TyrPro: 1.77 ± 0.036	1.677TyrGln: 1.677 ± 0.039	1.992TyrArg: 1.992 ± 0.035	2.672TyrSer: 2.672 ± 0.051	2.509TyrThr: 2.509 ± 0.044	2.31TyrVal: 2.31 ± 0.041	0.524TyrTrp: 0.524 ± 0.021	1.927TyrTyr: 1.927 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4731 proteins (1570989 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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