Amino acid dipepetide frequency for Lentinula edodes negative-strand RNA virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.296AlaAla: 2.296 ± 2.919
0.656AlaCys: 0.656 ± 0.622
1.968AlaAsp: 1.968 ± 1.214
1.64AlaGlu: 1.64 ± 0.417
1.64AlaPhe: 1.64 ± 0.417
2.624AlaGly: 2.624 ± 1.796
1.64AlaHis: 1.64 ± 1.164
0.984AlaIle: 0.984 ± 1.189
3.936AlaLys: 3.936 ± 3.008
5.576AlaLeu: 5.576 ± 3.422
1.968AlaMet: 1.968 ± 1.085
1.968AlaAsn: 1.968 ± 0.494
2.296AlaPro: 2.296 ± 1.503
2.296AlaGln: 2.296 ± 0.72
2.624AlaArg: 2.624 ± 0.795
5.576AlaSer: 5.576 ± 1.312
1.968AlaThr: 1.968 ± 0.62
2.624AlaVal: 2.624 ± 3.481
0.328AlaTrp: 0.328 ± 0.164
1.968AlaTyr: 1.968 ± 1.105
0.0AlaXaa: 0.0 ± 0.0
Cys
1.64CysAla: 1.64 ± 0.552
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.64CysGlu: 1.64 ± 0.552
1.312CysPhe: 1.312 ± 0.656
0.984CysGly: 0.984 ± 0.492
0.328CysHis: 0.328 ± 0.164
0.656CysIle: 0.656 ± 0.328
1.968CysLys: 1.968 ± 0.494
0.328CysLeu: 0.328 ± 0.164
0.328CysMet: 0.328 ± 0.164
0.328CysAsn: 0.328 ± 0.722
0.656CysPro: 0.656 ± 0.328
0.328CysGln: 0.328 ± 0.164
0.656CysArg: 0.656 ± 0.328
1.312CysSer: 1.312 ± 0.527
0.328CysThr: 0.328 ± 0.722
0.328CysVal: 0.328 ± 0.164
0.328CysTrp: 0.328 ± 0.658
0.328CysTyr: 0.328 ± 0.164
0.0CysXaa: 0.0 ± 0.0
Asp
1.312AspAla: 1.312 ± 0.656
0.328AspCys: 0.328 ± 0.164
5.248AspAsp: 5.248 ± 1.59
4.264AspGlu: 4.264 ± 1.094
4.264AspPhe: 4.264 ± 0.797
1.312AspGly: 1.312 ± 0.656
2.296AspHis: 2.296 ± 0.238
4.92AspIle: 4.92 ± 1.557
3.608AspLys: 3.608 ± 1.263
7.871AspLeu: 7.871 ± 2.795
1.968AspMet: 1.968 ± 0.985
1.312AspAsn: 1.312 ± 0.398
5.576AspPro: 5.576 ± 0.664
1.312AspGln: 1.312 ± 1.406
3.936AspArg: 3.936 ± 0.636
4.592AspSer: 4.592 ± 1.722
2.952AspThr: 2.952 ± 0.844
2.296AspVal: 2.296 ± 1.08
0.984AspTrp: 0.984 ± 0.492
1.64AspTyr: 1.64 ± 0.417
0.0AspXaa: 0.0 ± 0.0
Glu
5.248GluAla: 5.248 ± 0.77
0.984GluCys: 0.984 ± 0.492
6.888GluAsp: 6.888 ± 0.796
10.167GluGlu: 10.167 ± 3.519
3.936GluPhe: 3.936 ± 0.636
5.576GluGly: 5.576 ± 1.961
1.64GluHis: 1.64 ± 0.417
5.576GluIle: 5.576 ± 1.024
4.264GluLys: 4.264 ± 2.133
5.248GluLeu: 5.248 ± 0.905
3.608GluMet: 3.608 ± 0.476
2.624GluAsn: 2.624 ± 0.739
0.984GluPro: 0.984 ± 0.492
1.968GluGln: 1.968 ± 0.385
4.92GluArg: 4.92 ± 1.424
3.936GluSer: 3.936 ± 0.636
5.248GluThr: 5.248 ± 0.646
5.576GluVal: 5.576 ± 1.618
1.64GluTrp: 1.64 ± 0.417
2.296GluTyr: 2.296 ± 0.238
0.0GluXaa: 0.0 ± 0.0
Phe
1.312PheAla: 1.312 ± 1.5
1.968PheCys: 1.968 ± 1.214
3.608PheAsp: 3.608 ± 1.134
3.936PheGlu: 3.936 ± 0.988
1.64PhePhe: 1.64 ± 0.417
0.656PheGly: 0.656 ± 0.536
1.968PheHis: 1.968 ± 0.985
2.952PheIle: 2.952 ± 0.974
3.936PheLys: 3.936 ± 1.193
3.936PheLeu: 3.936 ± 1.414
1.64PheMet: 1.64 ± 0.773
3.608PheAsn: 3.608 ± 1.162
3.608PhePro: 3.608 ± 0.927
1.64PheGln: 1.64 ± 0.821
2.624PheArg: 2.624 ± 1.313
5.248PheSer: 5.248 ± 2.817
2.296PheThr: 2.296 ± 0.606
3.936PheVal: 3.936 ± 0.988
0.328PheTrp: 0.328 ± 0.164
2.624PheTyr: 2.624 ± 1.313
0.0PheXaa: 0.0 ± 0.0
Gly
1.968GlyAla: 1.968 ± 0.62
0.656GlyCys: 0.656 ± 0.328
0.656GlyAsp: 0.656 ± 0.328
4.264GlyGlu: 4.264 ± 0.67
2.624GlyPhe: 2.624 ± 1.054
0.984GlyGly: 0.984 ± 0.443
0.656GlyHis: 0.656 ± 0.536
3.936GlyIle: 3.936 ± 1.34
3.608GlyLys: 3.608 ± 0.9
3.608GlyLeu: 3.608 ± 1.162
2.296GlyMet: 2.296 ± 0.606
3.936GlyAsn: 3.936 ± 1.592
3.28GlyPro: 3.28 ± 1.271
0.0GlyGln: 0.0 ± 0.0
3.28GlyArg: 3.28 ± 0.834
4.592GlySer: 4.592 ± 2.291
2.296GlyThr: 2.296 ± 0.238
1.312GlyVal: 1.312 ± 0.398
0.328GlyTrp: 0.328 ± 0.722
0.656GlyTyr: 0.656 ± 0.328
0.0GlyXaa: 0.0 ± 0.0
His
0.656HisAla: 0.656 ± 0.328
0.0HisCys: 0.0 ± 0.0
0.656HisAsp: 0.656 ± 0.328
1.64HisGlu: 1.64 ± 0.821
2.952HisPhe: 2.952 ± 1.328
1.312HisGly: 1.312 ± 0.656
0.656HisHis: 0.656 ± 0.622
1.968HisIle: 1.968 ± 1.214
0.984HisLys: 0.984 ± 0.492
2.296HisLeu: 2.296 ± 0.238
0.328HisMet: 0.328 ± 0.164
1.64HisAsn: 1.64 ± 0.417
1.312HisPro: 1.312 ± 0.656
0.328HisGln: 0.328 ± 0.164
1.64HisArg: 1.64 ± 0.552
1.968HisSer: 1.968 ± 0.985
0.328HisThr: 0.328 ± 0.164
0.984HisVal: 0.984 ± 0.552
0.328HisTrp: 0.328 ± 0.164
1.312HisTyr: 1.312 ± 0.656
0.0HisXaa: 0.0 ± 0.0
Ile
4.92IleAla: 4.92 ± 1.19
1.64IleCys: 1.64 ± 0.552
4.592IleAsp: 4.592 ± 1.722
4.592IleGlu: 4.592 ± 1.656
3.936IlePhe: 3.936 ± 0.988
1.64IleGly: 1.64 ± 0.552
0.656IleHis: 0.656 ± 0.622
4.92IleIle: 4.92 ± 1.655
2.952IleLys: 2.952 ± 1.477
3.936IleLeu: 3.936 ± 0.636
1.968IleMet: 1.968 ± 0.385
2.624IleAsn: 2.624 ± 2.638
0.656IlePro: 0.656 ± 0.328
2.624IleGln: 2.624 ± 0.955
3.28IleArg: 3.28 ± 1.641
6.888IleSer: 6.888 ± 1.554
4.264IleThr: 4.264 ± 1.094
5.576IleVal: 5.576 ± 0.279
0.328IleTrp: 0.328 ± 0.164
1.64IleTyr: 1.64 ± 0.969
0.0IleXaa: 0.0 ± 0.0
Lys
4.592LysAla: 4.592 ± 1.095
0.656LysCys: 0.656 ± 0.536
6.232LysAsp: 6.232 ± 0.298
5.904LysGlu: 5.904 ± 0.45
3.28LysPhe: 3.28 ± 1.263
2.952LysGly: 2.952 ± 1.477
2.296LysHis: 2.296 ± 0.606
4.264LysIle: 4.264 ± 0.67
9.839LysLys: 9.839 ± 2.294
7.871LysLeu: 7.871 ± 1.381
2.296LysMet: 2.296 ± 0.72
2.952LysAsn: 2.952 ± 0.184
1.312LysPro: 1.312 ± 0.656
1.64LysGln: 1.64 ± 0.417
3.936LysArg: 3.936 ± 0.659
7.215LysSer: 7.215 ± 1.375
2.624LysThr: 2.624 ± 0.739
3.936LysVal: 3.936 ± 1.34
0.656LysTrp: 0.656 ± 0.328
2.952LysTyr: 2.952 ± 0.844
0.0LysXaa: 0.0 ± 0.0
Leu
3.28LeuAla: 3.28 ± 1.564
1.312LeuCys: 1.312 ± 0.656
5.904LeuAsp: 5.904 ± 0.955
7.871LeuGlu: 7.871 ± 1.318
4.264LeuPhe: 4.264 ± 2.166
7.543LeuGly: 7.543 ± 1.771
2.624LeuHis: 2.624 ± 0.739
4.92LeuIle: 4.92 ± 0.801
9.839LeuLys: 9.839 ± 0.94
7.215LeuLeu: 7.215 ± 0.83
2.624LeuMet: 2.624 ± 0.955
2.296LeuAsn: 2.296 ± 0.238
3.28LeuPro: 3.28 ± 1.085
1.312LeuGln: 1.312 ± 1.406
3.608LeuArg: 3.608 ± 0.476
9.183LeuSer: 9.183 ± 0.744
5.576LeuThr: 5.576 ± 1.449
3.936LeuVal: 3.936 ± 0.771
0.984LeuTrp: 0.984 ± 0.492
1.64LeuTyr: 1.64 ± 0.821
0.0LeuXaa: 0.0 ± 0.0
Met
3.28MetAla: 3.28 ± 0.322
0.328MetCys: 0.328 ± 0.164
0.656MetAsp: 0.656 ± 0.328
1.968MetGlu: 1.968 ± 0.494
2.296MetPhe: 2.296 ± 0.606
0.656MetGly: 0.656 ± 0.328
0.656MetHis: 0.656 ± 0.328
1.968MetIle: 1.968 ± 0.385
3.608MetLys: 3.608 ± 3.622
1.64MetLeu: 1.64 ± 0.552
0.984MetMet: 0.984 ± 0.443
3.608MetAsn: 3.608 ± 0.9
0.328MetPro: 0.328 ± 0.164
0.328MetGln: 0.328 ± 0.164
1.64MetArg: 1.64 ± 0.821
2.296MetSer: 2.296 ± 0.606
1.968MetThr: 1.968 ± 0.385
1.968MetVal: 1.968 ± 0.62
0.328MetTrp: 0.328 ± 0.164
0.656MetTyr: 0.656 ± 0.328
0.0MetXaa: 0.0 ± 0.0
Asn
1.312AsnAla: 1.312 ± 1.5
0.328AsnCys: 0.328 ± 0.164
2.624AsnAsp: 2.624 ± 1.408
2.952AsnGlu: 2.952 ± 0.184
1.968AsnPhe: 1.968 ± 0.985
1.312AsnGly: 1.312 ± 0.703
1.312AsnHis: 1.312 ± 0.398
3.936AsnIle: 3.936 ± 1.581
4.592AsnLys: 4.592 ± 1.21
5.904AsnLeu: 5.904 ± 1.155
0.984AsnMet: 0.984 ± 0.552
3.608AsnAsn: 3.608 ± 0.476
0.984AsnPro: 0.984 ± 0.492
0.656AsnGln: 0.656 ± 0.536
2.296AsnArg: 2.296 ± 1.568
6.56AsnSer: 6.56 ± 0.855
2.296AsnThr: 2.296 ± 0.606
2.624AsnVal: 2.624 ± 0.739
0.656AsnTrp: 0.656 ± 0.536
1.64AsnTyr: 1.64 ± 0.552
0.0AsnXaa: 0.0 ± 0.0
Pro
1.312ProAla: 1.312 ± 0.527
0.0ProCys: 0.0 ± 0.0
3.28ProAsp: 3.28 ± 1.031
2.624ProGlu: 2.624 ± 0.739
1.64ProPhe: 1.64 ± 0.417
0.984ProGly: 0.984 ± 0.492
1.312ProHis: 1.312 ± 0.656
1.64ProIle: 1.64 ± 0.417
2.624ProLys: 2.624 ± 0.841
2.952ProLeu: 2.952 ± 0.881
1.968ProMet: 1.968 ± 1.418
2.296ProAsn: 2.296 ± 1.503
0.328ProPro: 0.328 ± 0.658
0.984ProGln: 0.984 ± 0.865
0.984ProArg: 0.984 ± 1.649
3.936ProSer: 3.936 ± 1.421
2.624ProThr: 2.624 ± 0.739
2.296ProVal: 2.296 ± 0.238
0.328ProTrp: 0.328 ± 0.164
2.296ProTyr: 2.296 ± 0.72
0.0ProXaa: 0.0 ± 0.0
Gln
2.624GlnAla: 2.624 ± 2.757
0.328GlnCys: 0.328 ± 0.164
0.656GlnAsp: 0.656 ± 0.328
2.952GlnGlu: 2.952 ± 0.184
1.968GlnPhe: 1.968 ± 0.985
0.984GlnGly: 0.984 ± 0.443
0.984GlnHis: 0.984 ± 0.492
0.328GlnIle: 0.328 ± 0.722
2.624GlnLys: 2.624 ± 0.135
1.64GlnLeu: 1.64 ± 0.552
0.656GlnMet: 0.656 ± 0.536
0.984GlnAsn: 0.984 ± 0.492
0.656GlnPro: 0.656 ± 0.328
0.656GlnGln: 0.656 ± 0.622
1.968GlnArg: 1.968 ± 1.214
1.312GlnSer: 1.312 ± 1.072
1.64GlnThr: 1.64 ± 0.543
0.984GlnVal: 0.984 ± 0.552
0.328GlnTrp: 0.328 ± 0.164
0.656GlnTyr: 0.656 ± 0.328
0.0GlnXaa: 0.0 ± 0.0
Arg
1.312ArgAla: 1.312 ± 0.398
0.656ArgCys: 0.656 ± 0.328
4.264ArgAsp: 4.264 ± 0.797
4.592ArgGlu: 4.592 ± 1.65
2.624ArgPhe: 2.624 ± 0.771
2.624ArgGly: 2.624 ± 1.561
0.328ArgHis: 0.328 ± 0.164
4.92ArgIle: 4.92 ± 0.35
4.592ArgLys: 4.592 ± 1.722
6.232ArgLeu: 6.232 ± 1.952
1.312ArgMet: 1.312 ± 0.398
3.28ArgAsn: 3.28 ± 0.476
0.656ArgPro: 0.656 ± 0.328
1.968ArgGln: 1.968 ± 0.62
2.296ArgArg: 2.296 ± 0.825
5.576ArgSer: 5.576 ± 2.732
2.296ArgThr: 2.296 ± 0.927
3.28ArgVal: 3.28 ± 0.476
0.328ArgTrp: 0.328 ± 0.164
1.968ArgTyr: 1.968 ± 0.62
0.0ArgXaa: 0.0 ± 0.0
Ser
3.28SerAla: 3.28 ± 1.564
0.984SerCys: 0.984 ± 0.552
6.232SerAsp: 6.232 ± 1.911
8.855SerGlu: 8.855 ± 1.756
6.56SerPhe: 6.56 ± 0.169
3.936SerGly: 3.936 ± 1.792
0.984SerHis: 0.984 ± 0.492
5.576SerIle: 5.576 ± 1.229
3.936SerLys: 3.936 ± 0.274
9.183SerLeu: 9.183 ± 1.489
1.968SerMet: 1.968 ± 0.888
4.92SerAsn: 4.92 ± 0.712
3.28SerPro: 3.28 ± 1.271
1.968SerGln: 1.968 ± 0.494
6.888SerArg: 6.888 ± 1.596
8.527SerSer: 8.527 ± 2.555
4.92SerThr: 4.92 ± 1.628
9.511SerVal: 9.511 ± 1.85
0.0SerTrp: 0.0 ± 0.0
3.28SerTyr: 3.28 ± 2.432
0.0SerXaa: 0.0 ± 0.0
Thr
1.64ThrAla: 1.64 ± 1.723
0.656ThrCys: 0.656 ± 0.328
2.624ThrAsp: 2.624 ± 1.713
3.608ThrGlu: 3.608 ± 0.688
2.296ThrPhe: 2.296 ± 1.503
2.624ThrGly: 2.624 ± 1.313
0.656ThrHis: 0.656 ± 0.328
3.936ThrIle: 3.936 ± 1.414
2.624ThrLys: 2.624 ± 1.406
3.608ThrLeu: 3.608 ± 1.263
0.984ThrMet: 0.984 ± 0.443
1.64ThrAsn: 1.64 ± 0.821
2.952ThrPro: 2.952 ± 0.881
1.968ThrGln: 1.968 ± 0.385
2.296ThrArg: 2.296 ± 0.825
5.904ThrSer: 5.904 ± 1.777
2.624ThrThr: 2.624 ± 1.408
3.608ThrVal: 3.608 ± 1.162
0.984ThrTrp: 0.984 ± 0.492
1.968ThrTyr: 1.968 ± 0.494
0.0ThrXaa: 0.0 ± 0.0
Val
2.952ValAla: 2.952 ± 3.684
0.328ValCys: 0.328 ± 0.164
4.264ValAsp: 4.264 ± 0.67
5.248ValGlu: 5.248 ± 1.59
1.64ValPhe: 1.64 ± 0.417
2.952ValGly: 2.952 ± 0.619
0.328ValHis: 0.328 ± 0.164
4.592ValIle: 4.592 ± 0.959
4.264ValLys: 4.264 ± 1.094
5.248ValLeu: 5.248 ± 1.711
1.968ValMet: 1.968 ± 0.985
2.296ValAsn: 2.296 ± 1.149
2.624ValPro: 2.624 ± 0.135
1.968ValGln: 1.968 ± 0.985
2.624ValArg: 2.624 ± 1.561
7.543ValSer: 7.543 ± 1.111
1.64ValThr: 1.64 ± 0.543
2.624ValVal: 2.624 ± 0.135
0.984ValTrp: 0.984 ± 0.443
2.952ValTyr: 2.952 ± 1.245
0.0ValXaa: 0.0 ± 0.0
Trp
0.328TrpAla: 0.328 ± 0.164
0.656TrpCys: 0.656 ± 0.328
0.0TrpAsp: 0.0 ± 0.0
0.984TrpGlu: 0.984 ± 0.492
0.656TrpPhe: 0.656 ± 0.328
0.984TrpGly: 0.984 ± 0.443
0.328TrpHis: 0.328 ± 0.164
0.656TrpIle: 0.656 ± 0.328
0.656TrpLys: 0.656 ± 0.328
0.984TrpLeu: 0.984 ± 1.189
0.328TrpMet: 0.328 ± 0.164
0.328TrpAsn: 0.328 ± 0.164
0.656TrpPro: 0.656 ± 0.622
0.328TrpGln: 0.328 ± 0.164
1.64TrpArg: 1.64 ± 0.417
0.328TrpSer: 0.328 ± 0.164
0.656TrpThr: 0.656 ± 0.328
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.312TyrAla: 1.312 ± 1.5
1.312TyrCys: 1.312 ± 0.656
1.64TyrAsp: 1.64 ± 0.969
2.624TyrGlu: 2.624 ± 0.135
1.968TyrPhe: 1.968 ± 0.985
2.296TyrGly: 2.296 ± 1.149
1.64TyrHis: 1.64 ± 0.552
0.984TyrIle: 0.984 ± 1.189
2.952TyrLys: 2.952 ± 0.974
3.936TyrLeu: 3.936 ± 0.659
0.656TyrMet: 0.656 ± 0.328
2.296TyrAsn: 2.296 ± 1.08
0.984TyrPro: 0.984 ± 0.492
0.656TyrGln: 0.656 ± 1.444
1.968TyrArg: 1.968 ± 0.985
2.624TyrSer: 2.624 ± 0.771
0.656TyrThr: 0.656 ± 0.622
1.64TyrVal: 1.64 ± 0.417
0.328TyrTrp: 0.328 ± 0.164
1.312TyrTyr: 1.312 ± 0.656
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski