Amino acid dipepetide frequency for Changjiang tombus-like virus 19

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.282AlaAla: 3.282 ± 2.652
2.188AlaCys: 2.188 ± 0.23
0.0AlaAsp: 0.0 ± 0.0
2.188AlaGlu: 2.188 ± 0.23
0.0AlaPhe: 0.0 ± 0.0
6.565AlaGly: 6.565 ± 2.229
1.094AlaHis: 1.094 ± 0.884
3.282AlaIle: 3.282 ± 0.423
3.282AlaLys: 3.282 ± 1.96
10.941AlaLeu: 10.941 ± 2.69
4.376AlaMet: 4.376 ± 0.461
6.565AlaAsn: 6.565 ± 0.846
4.376AlaPro: 4.376 ± 0.461
2.188AlaGln: 2.188 ± 0.23
3.282AlaArg: 3.282 ± 2.652
4.376AlaSer: 4.376 ± 1.998
2.188AlaThr: 2.188 ± 1.768
4.376AlaVal: 4.376 ± 3.536
2.188AlaTrp: 2.188 ± 1.307
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.188CysAla: 2.188 ± 0.23
0.0CysCys: 0.0 ± 0.0
3.282CysAsp: 3.282 ± 1.114
4.376CysGlu: 4.376 ± 1.077
2.188CysPhe: 2.188 ± 1.307
1.094CysGly: 1.094 ± 0.884
1.094CysHis: 1.094 ± 0.884
0.0CysIle: 0.0 ± 0.0
2.188CysLys: 2.188 ± 1.307
2.188CysLeu: 2.188 ± 0.23
1.094CysMet: 1.094 ± 0.653
2.188CysAsn: 2.188 ± 0.23
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.188CysSer: 2.188 ± 1.307
3.282CysThr: 3.282 ± 0.423
1.094CysVal: 1.094 ± 0.653
0.0CysTrp: 0.0 ± 0.0
1.094CysTyr: 1.094 ± 0.653
0.0CysXaa: 0.0 ± 0.0
Asp
5.47AspAla: 5.47 ± 0.193
1.094AspCys: 1.094 ± 0.653
4.376AspAsp: 4.376 ± 0.461
1.094AspGlu: 1.094 ± 0.884
1.094AspPhe: 1.094 ± 0.653
5.47AspGly: 5.47 ± 1.73
1.094AspHis: 1.094 ± 0.884
4.376AspIle: 4.376 ± 0.461
4.376AspLys: 4.376 ± 1.077
3.282AspLeu: 3.282 ± 0.423
1.094AspMet: 1.094 ± 0.884
5.47AspAsn: 5.47 ± 0.193
3.282AspPro: 3.282 ± 1.114
3.282AspGln: 3.282 ± 0.423
4.376AspArg: 4.376 ± 0.461
2.188AspSer: 2.188 ± 1.307
2.188AspThr: 2.188 ± 1.307
0.0AspVal: 0.0 ± 0.0
2.188AspTrp: 2.188 ± 1.307
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
2.188GluCys: 2.188 ± 0.23
0.0GluAsp: 0.0 ± 0.0
2.188GluGlu: 2.188 ± 0.23
3.282GluPhe: 3.282 ± 1.96
1.094GluGly: 1.094 ± 0.653
2.188GluHis: 2.188 ± 1.768
2.188GluIle: 2.188 ± 1.307
0.0GluLys: 0.0 ± 0.0
2.188GluLeu: 2.188 ± 1.307
1.094GluMet: 1.094 ± 0.884
2.188GluAsn: 2.188 ± 0.23
2.188GluPro: 2.188 ± 1.307
2.188GluGln: 2.188 ± 1.307
2.188GluArg: 2.188 ± 0.23
3.282GluSer: 3.282 ± 1.96
3.282GluThr: 3.282 ± 1.114
3.282GluVal: 3.282 ± 1.96
0.0GluTrp: 0.0 ± 0.0
1.094GluTyr: 1.094 ± 0.653
0.0GluXaa: 0.0 ± 0.0
Phe
5.47PheAla: 5.47 ± 0.193
2.188PheCys: 2.188 ± 1.307
2.188PheAsp: 2.188 ± 1.307
0.0PheGlu: 0.0 ± 0.0
1.094PhePhe: 1.094 ± 0.653
2.188PheGly: 2.188 ± 1.307
2.188PheHis: 2.188 ± 0.23
3.282PheIle: 3.282 ± 0.423
5.47PheLys: 5.47 ± 1.73
4.376PheLeu: 4.376 ± 1.077
1.094PheMet: 1.094 ± 0.884
4.376PheAsn: 4.376 ± 2.614
1.094PhePro: 1.094 ± 0.653
1.094PheGln: 1.094 ± 0.653
2.188PheArg: 2.188 ± 1.768
2.188PheSer: 2.188 ± 1.307
4.376PheThr: 4.376 ± 1.998
2.188PheVal: 2.188 ± 1.307
1.094PheTrp: 1.094 ± 0.653
2.188PheTyr: 2.188 ± 1.307
0.0PheXaa: 0.0 ± 0.0
Gly
1.094GlyAla: 1.094 ± 0.884
2.188GlyCys: 2.188 ± 1.307
3.282GlyAsp: 3.282 ± 1.96
1.094GlyGlu: 1.094 ± 0.653
4.376GlyPhe: 4.376 ± 0.461
5.47GlyGly: 5.47 ± 1.345
2.188GlyHis: 2.188 ± 1.307
3.282GlyIle: 3.282 ± 1.114
3.282GlyLys: 3.282 ± 1.96
4.376GlyLeu: 4.376 ± 2.614
1.094GlyMet: 1.094 ± 0.515
2.188GlyAsn: 2.188 ± 1.307
2.188GlyPro: 2.188 ± 0.23
2.188GlyGln: 2.188 ± 1.307
5.47GlyArg: 5.47 ± 1.345
5.47GlySer: 5.47 ± 2.882
0.0GlyThr: 0.0 ± 0.0
6.565GlyVal: 6.565 ± 2.229
1.094GlyTrp: 1.094 ± 0.653
1.094GlyTyr: 1.094 ± 0.653
0.0GlyXaa: 0.0 ± 0.0
His
1.094HisAla: 1.094 ± 0.884
1.094HisCys: 1.094 ± 0.884
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
3.282HisPhe: 3.282 ± 0.423
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.094HisIle: 1.094 ± 0.653
3.282HisLys: 3.282 ± 0.423
2.188HisLeu: 2.188 ± 1.768
1.094HisMet: 1.094 ± 0.884
4.376HisAsn: 4.376 ± 1.998
1.094HisPro: 1.094 ± 0.884
1.094HisGln: 1.094 ± 0.884
1.094HisArg: 1.094 ± 0.884
2.188HisSer: 2.188 ± 0.23
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.282IleAla: 3.282 ± 1.114
2.188IleCys: 2.188 ± 1.307
5.47IleAsp: 5.47 ± 1.345
3.282IleGlu: 3.282 ± 1.96
1.094IlePhe: 1.094 ± 0.653
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
4.376IleIle: 4.376 ± 0.461
5.47IleLys: 5.47 ± 3.267
3.282IleLeu: 3.282 ± 1.114
2.188IleMet: 2.188 ± 0.78
6.565IleAsn: 6.565 ± 0.691
3.282IlePro: 3.282 ± 0.423
4.376IleGln: 4.376 ± 1.998
3.282IleArg: 3.282 ± 1.114
0.0IleSer: 0.0 ± 0.0
2.188IleThr: 2.188 ± 0.23
4.376IleVal: 4.376 ± 0.461
0.0IleTrp: 0.0 ± 0.0
1.094IleTyr: 1.094 ± 0.884
0.0IleXaa: 0.0 ± 0.0
Lys
1.094LysAla: 1.094 ± 0.653
0.0LysCys: 0.0 ± 0.0
4.376LysAsp: 4.376 ± 1.077
1.094LysGlu: 1.094 ± 0.653
3.282LysPhe: 3.282 ± 1.96
5.47LysGly: 5.47 ± 1.73
1.094LysHis: 1.094 ± 0.653
3.282LysIle: 3.282 ± 1.96
0.0LysLys: 0.0 ± 0.0
4.376LysLeu: 4.376 ± 1.077
1.094LysMet: 1.094 ± 0.653
4.376LysAsn: 4.376 ± 2.614
2.188LysPro: 2.188 ± 1.307
3.282LysGln: 3.282 ± 1.96
5.47LysArg: 5.47 ± 3.267
1.094LysSer: 1.094 ± 0.653
3.282LysThr: 3.282 ± 1.96
5.47LysVal: 5.47 ± 1.73
0.0LysTrp: 0.0 ± 0.0
2.188LysTyr: 2.188 ± 1.768
0.0LysXaa: 0.0 ± 0.0
Leu
3.282LeuAla: 3.282 ± 1.114
1.094LeuCys: 1.094 ± 0.653
6.565LeuAsp: 6.565 ± 0.691
1.094LeuGlu: 1.094 ± 0.884
3.282LeuPhe: 3.282 ± 1.96
3.282LeuGly: 3.282 ± 0.423
1.094LeuHis: 1.094 ± 0.653
7.659LeuIle: 7.659 ± 1.5
6.565LeuLys: 6.565 ± 2.383
4.376LeuLeu: 4.376 ± 0.461
1.094LeuMet: 1.094 ± 0.653
10.941LeuAsn: 10.941 ± 4.227
1.094LeuPro: 1.094 ± 0.653
4.376LeuGln: 4.376 ± 0.461
3.282LeuArg: 3.282 ± 0.423
5.47LeuSer: 5.47 ± 0.193
4.376LeuThr: 4.376 ± 1.077
3.282LeuVal: 3.282 ± 1.96
0.0LeuTrp: 0.0 ± 0.0
4.376LeuTyr: 4.376 ± 0.461
0.0LeuXaa: 0.0 ± 0.0
Met
2.188MetAla: 2.188 ± 1.307
1.094MetCys: 1.094 ± 0.884
1.094MetAsp: 1.094 ± 0.884
1.094MetGlu: 1.094 ± 0.884
1.094MetPhe: 1.094 ± 0.884
1.094MetGly: 1.094 ± 0.653
0.0MetHis: 0.0 ± 0.0
1.094MetIle: 1.094 ± 0.884
1.094MetLys: 1.094 ± 0.653
1.094MetLeu: 1.094 ± 0.884
0.0MetMet: 0.0 ± 0.0
2.188MetAsn: 2.188 ± 1.307
0.0MetPro: 0.0 ± 0.0
1.094MetGln: 1.094 ± 0.884
4.376MetArg: 4.376 ± 1.998
3.282MetSer: 3.282 ± 1.114
1.094MetThr: 1.094 ± 0.653
3.282MetVal: 3.282 ± 1.114
1.094MetTrp: 1.094 ± 0.884
2.188MetTyr: 2.188 ± 0.23
0.0MetXaa: 0.0 ± 0.0
Asn
12.035AsnAla: 12.035 ± 2.036
2.188AsnCys: 2.188 ± 1.307
5.47AsnAsp: 5.47 ± 1.73
2.188AsnGlu: 2.188 ± 0.23
3.282AsnPhe: 3.282 ± 0.423
6.565AsnGly: 6.565 ± 0.691
1.094AsnHis: 1.094 ± 0.884
2.188AsnIle: 2.188 ± 0.23
2.188AsnLys: 2.188 ± 1.307
8.753AsnLeu: 8.753 ± 0.616
2.188AsnMet: 2.188 ± 1.768
4.376AsnAsn: 4.376 ± 3.536
3.282AsnPro: 3.282 ± 2.652
0.0AsnGln: 0.0 ± 0.0
3.282AsnArg: 3.282 ± 1.114
6.565AsnSer: 6.565 ± 0.846
6.565AsnThr: 6.565 ± 0.691
4.376AsnVal: 4.376 ± 0.461
2.188AsnTrp: 2.188 ± 0.23
3.282AsnTyr: 3.282 ± 0.423
0.0AsnXaa: 0.0 ± 0.0
Pro
6.565ProAla: 6.565 ± 3.766
1.094ProCys: 1.094 ± 0.884
1.094ProAsp: 1.094 ± 0.884
2.188ProGlu: 2.188 ± 1.307
3.282ProPhe: 3.282 ± 1.96
2.188ProGly: 2.188 ± 1.307
1.094ProHis: 1.094 ± 0.653
1.094ProIle: 1.094 ± 0.884
1.094ProLys: 1.094 ± 0.653
1.094ProLeu: 1.094 ± 0.653
0.0ProMet: 0.0 ± 0.0
3.282ProAsn: 3.282 ± 0.423
0.0ProPro: 0.0 ± 0.0
1.094ProGln: 1.094 ± 0.653
6.565ProArg: 6.565 ± 2.383
2.188ProSer: 2.188 ± 0.23
3.282ProThr: 3.282 ± 2.652
1.094ProVal: 1.094 ± 0.653
0.0ProTrp: 0.0 ± 0.0
1.094ProTyr: 1.094 ± 0.884
0.0ProXaa: 0.0 ± 0.0
Gln
1.094GlnAla: 1.094 ± 0.653
2.188GlnCys: 2.188 ± 1.307
0.0GlnAsp: 0.0 ± 0.0
2.188GlnGlu: 2.188 ± 1.307
1.094GlnPhe: 1.094 ± 0.884
0.0GlnGly: 0.0 ± 0.0
2.188GlnHis: 2.188 ± 1.768
2.188GlnIle: 2.188 ± 0.23
2.188GlnLys: 2.188 ± 1.307
2.188GlnLeu: 2.188 ± 0.23
0.0GlnMet: 0.0 ± 0.0
3.282GlnAsn: 3.282 ± 2.652
1.094GlnPro: 1.094 ± 0.653
3.282GlnGln: 3.282 ± 1.114
5.47GlnArg: 5.47 ± 0.193
3.282GlnSer: 3.282 ± 0.423
1.094GlnThr: 1.094 ± 0.884
1.094GlnVal: 1.094 ± 0.884
3.282GlnTrp: 3.282 ± 0.423
2.188GlnTyr: 2.188 ± 0.23
0.0GlnXaa: 0.0 ± 0.0
Arg
5.47ArgAla: 5.47 ± 2.882
3.282ArgCys: 3.282 ± 1.96
3.282ArgAsp: 3.282 ± 1.96
2.188ArgGlu: 2.188 ± 1.307
4.376ArgPhe: 4.376 ± 0.461
6.565ArgGly: 6.565 ± 0.691
1.094ArgHis: 1.094 ± 0.884
3.282ArgIle: 3.282 ± 0.423
1.094ArgLys: 1.094 ± 0.653
2.188ArgLeu: 2.188 ± 0.23
3.282ArgMet: 3.282 ± 1.114
3.282ArgAsn: 3.282 ± 2.652
3.282ArgPro: 3.282 ± 0.423
3.282ArgGln: 3.282 ± 2.652
7.659ArgArg: 7.659 ± 1.575
2.188ArgSer: 2.188 ± 1.307
3.282ArgThr: 3.282 ± 2.652
4.376ArgVal: 4.376 ± 0.461
2.188ArgTrp: 2.188 ± 0.23
4.376ArgTyr: 4.376 ± 2.614
0.0ArgXaa: 0.0 ± 0.0
Ser
4.376SerAla: 4.376 ± 1.998
1.094SerCys: 1.094 ± 0.653
7.659SerAsp: 7.659 ± 0.038
1.094SerGlu: 1.094 ± 0.653
3.282SerPhe: 3.282 ± 1.96
4.376SerGly: 4.376 ± 0.461
0.0SerHis: 0.0 ± 0.0
5.47SerIle: 5.47 ± 1.345
0.0SerLys: 0.0 ± 0.0
7.659SerLeu: 7.659 ± 1.5
2.188SerMet: 2.188 ± 0.23
0.0SerAsn: 0.0 ± 0.0
1.094SerPro: 1.094 ± 0.653
2.188SerGln: 2.188 ± 1.307
3.282SerArg: 3.282 ± 0.423
6.565SerSer: 6.565 ± 0.846
3.282SerThr: 3.282 ± 0.423
4.376SerVal: 4.376 ± 0.461
1.094SerTrp: 1.094 ± 0.653
3.282SerTyr: 3.282 ± 2.652
0.0SerXaa: 0.0 ± 0.0
Thr
3.282ThrAla: 3.282 ± 1.114
0.0ThrCys: 0.0 ± 0.0
1.094ThrAsp: 1.094 ± 0.653
3.282ThrGlu: 3.282 ± 0.423
3.282ThrPhe: 3.282 ± 1.114
2.188ThrGly: 2.188 ± 1.307
2.188ThrHis: 2.188 ± 1.768
1.094ThrIle: 1.094 ± 0.884
3.282ThrLys: 3.282 ± 0.423
2.188ThrLeu: 2.188 ± 1.307
1.094ThrMet: 1.094 ± 0.884
5.47ThrAsn: 5.47 ± 0.193
5.47ThrPro: 5.47 ± 1.73
1.094ThrGln: 1.094 ± 0.884
1.094ThrArg: 1.094 ± 0.884
3.282ThrSer: 3.282 ± 1.114
6.565ThrThr: 6.565 ± 2.229
3.282ThrVal: 3.282 ± 1.114
3.282ThrTrp: 3.282 ± 2.652
2.188ThrTyr: 2.188 ± 1.307
0.0ThrXaa: 0.0 ± 0.0
Val
2.188ValAla: 2.188 ± 1.307
1.094ValCys: 1.094 ± 0.884
3.282ValAsp: 3.282 ± 0.423
4.376ValGlu: 4.376 ± 2.614
2.188ValPhe: 2.188 ± 0.23
2.188ValGly: 2.188 ± 0.23
3.282ValHis: 3.282 ± 1.114
4.376ValIle: 4.376 ± 1.998
4.376ValLys: 4.376 ± 1.077
3.282ValLeu: 3.282 ± 1.96
4.376ValMet: 4.376 ± 0.461
5.47ValAsn: 5.47 ± 2.882
2.188ValPro: 2.188 ± 1.768
2.188ValGln: 2.188 ± 0.23
3.282ValArg: 3.282 ± 0.423
5.47ValSer: 5.47 ± 1.345
2.188ValThr: 2.188 ± 1.307
5.47ValVal: 5.47 ± 2.882
0.0ValTrp: 0.0 ± 0.0
2.188ValTyr: 2.188 ± 0.23
0.0ValXaa: 0.0 ± 0.0
Trp
1.094TrpAla: 1.094 ± 0.653
0.0TrpCys: 0.0 ± 0.0
1.094TrpAsp: 1.094 ± 0.653
0.0TrpGlu: 0.0 ± 0.0
2.188TrpPhe: 2.188 ± 1.307
1.094TrpGly: 1.094 ± 0.653
0.0TrpHis: 0.0 ± 0.0
1.094TrpIle: 1.094 ± 0.884
0.0TrpLys: 0.0 ± 0.0
3.282TrpLeu: 3.282 ± 1.114
0.0TrpMet: 0.0 ± 0.0
1.094TrpAsn: 1.094 ± 0.653
2.188TrpPro: 2.188 ± 0.23
0.0TrpGln: 0.0 ± 0.0
2.188TrpArg: 2.188 ± 0.23
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
4.376TrpVal: 4.376 ± 0.461
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.188TyrAla: 2.188 ± 1.768
3.282TyrCys: 3.282 ± 2.652
2.188TyrAsp: 2.188 ± 0.23
1.094TyrGlu: 1.094 ± 0.884
3.282TyrPhe: 3.282 ± 0.423
1.094TyrGly: 1.094 ± 0.653
0.0TyrHis: 0.0 ± 0.0
2.188TyrIle: 2.188 ± 0.23
3.282TyrLys: 3.282 ± 1.96
3.282TyrLeu: 3.282 ± 0.423
0.0TyrMet: 0.0 ± 0.0
4.376TyrAsn: 4.376 ± 1.077
0.0TyrPro: 0.0 ± 0.0
1.094TyrGln: 1.094 ± 0.884
2.188TyrArg: 2.188 ± 1.307
1.094TyrSer: 1.094 ± 0.653
2.188TyrThr: 2.188 ± 0.23
1.094TyrVal: 1.094 ± 0.653
0.0TyrTrp: 0.0 ± 0.0
1.094TyrTyr: 1.094 ± 0.653
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (915 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski