Amino acid dipepetide frequency for Fowl aviadenovirus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.628AlaAla: 6.628 ± 0.954
1.767AlaCys: 1.767 ± 0.479
4.242AlaAsp: 4.242 ± 0.609
4.419AlaGlu: 4.419 ± 0.867
2.651AlaPhe: 2.651 ± 0.372
5.214AlaGly: 5.214 ± 0.781
1.856AlaHis: 1.856 ± 0.509
4.684AlaIle: 4.684 ± 0.583
2.563AlaLys: 2.563 ± 0.503
8.13AlaLeu: 8.13 ± 0.892
1.591AlaMet: 1.591 ± 0.552
2.916AlaAsn: 2.916 ± 0.391
5.214AlaPro: 5.214 ± 0.663
2.916AlaGln: 2.916 ± 0.508
5.479AlaArg: 5.479 ± 0.928
5.744AlaSer: 5.744 ± 0.875
5.302AlaThr: 5.302 ± 0.785
5.656AlaVal: 5.656 ± 0.694
0.619AlaTrp: 0.619 ± 0.221
2.916AlaTyr: 2.916 ± 0.528
0.0AlaXaa: 0.0 ± 0.0
Cys
1.326CysAla: 1.326 ± 0.457
0.265CysCys: 0.265 ± 0.141
0.884CysAsp: 0.884 ± 0.408
0.442CysGlu: 0.442 ± 0.193
0.972CysPhe: 0.972 ± 0.413
1.326CysGly: 1.326 ± 0.368
0.884CysHis: 0.884 ± 0.33
0.707CysIle: 0.707 ± 0.293
0.884CysLys: 0.884 ± 0.356
1.502CysLeu: 1.502 ± 0.408
0.795CysMet: 0.795 ± 0.245
1.149CysAsn: 1.149 ± 0.399
0.972CysPro: 0.972 ± 0.337
0.177CysGln: 0.177 ± 0.11
0.795CysArg: 0.795 ± 0.209
1.591CysSer: 1.591 ± 0.376
0.619CysThr: 0.619 ± 0.278
0.707CysVal: 0.707 ± 0.18
0.442CysTrp: 0.442 ± 0.171
0.884CysTyr: 0.884 ± 0.256
0.0CysXaa: 0.0 ± 0.0
Asp
3.358AspAla: 3.358 ± 0.69
0.884AspCys: 0.884 ± 0.296
3.446AspAsp: 3.446 ± 0.716
3.27AspGlu: 3.27 ± 0.454
1.944AspPhe: 1.944 ± 0.437
3.8AspGly: 3.8 ± 0.763
0.795AspHis: 0.795 ± 0.222
3.181AspIle: 3.181 ± 0.577
1.326AspLys: 1.326 ± 0.399
5.744AspLeu: 5.744 ± 0.584
0.884AspMet: 0.884 ± 0.385
2.651AspAsn: 2.651 ± 0.63
4.949AspPro: 4.949 ± 0.757
1.856AspGln: 1.856 ± 0.334
3.358AspArg: 3.358 ± 0.607
3.358AspSer: 3.358 ± 0.513
3.005AspThr: 3.005 ± 0.523
2.739AspVal: 2.739 ± 0.445
1.149AspTrp: 1.149 ± 0.329
1.944AspTyr: 1.944 ± 0.382
0.0AspXaa: 0.0 ± 0.0
Glu
4.507GluAla: 4.507 ± 0.627
0.795GluCys: 0.795 ± 0.331
2.916GluAsp: 2.916 ± 0.605
5.921GluGlu: 5.921 ± 1.344
1.149GluPhe: 1.149 ± 0.308
3.093GluGly: 3.093 ± 0.496
1.679GluHis: 1.679 ± 0.391
1.944GluIle: 1.944 ± 0.412
2.209GluLys: 2.209 ± 0.421
5.391GluLeu: 5.391 ± 0.589
1.326GluMet: 1.326 ± 0.329
1.326GluAsn: 1.326 ± 0.285
3.181GluPro: 3.181 ± 0.513
2.033GluGln: 2.033 ± 0.549
4.065GluArg: 4.065 ± 0.721
3.27GluSer: 3.27 ± 0.499
3.005GluThr: 3.005 ± 0.581
3.712GluVal: 3.712 ± 0.449
0.795GluTrp: 0.795 ± 0.274
1.06GluTyr: 1.06 ± 0.321
0.0GluXaa: 0.0 ± 0.0
Phe
2.651PheAla: 2.651 ± 0.474
0.442PheCys: 0.442 ± 0.252
2.739PheAsp: 2.739 ± 0.583
1.856PheGlu: 1.856 ± 0.367
1.767PhePhe: 1.767 ± 0.405
1.679PheGly: 1.679 ± 0.408
1.591PheHis: 1.591 ± 0.387
1.502PheIle: 1.502 ± 0.375
2.121PheLys: 2.121 ± 0.347
3.8PheLeu: 3.8 ± 0.692
1.237PheMet: 1.237 ± 0.353
1.944PheAsn: 1.944 ± 0.343
2.209PhePro: 2.209 ± 0.437
0.884PheGln: 0.884 ± 0.275
2.651PheArg: 2.651 ± 0.533
2.828PheSer: 2.828 ± 0.475
3.181PheThr: 3.181 ± 0.491
2.651PheVal: 2.651 ± 0.476
0.619PheTrp: 0.619 ± 0.204
2.033PheTyr: 2.033 ± 0.321
0.0PheXaa: 0.0 ± 0.0
Gly
6.451GlyAla: 6.451 ± 0.767
0.707GlyCys: 0.707 ± 0.218
2.563GlyAsp: 2.563 ± 0.506
3.27GlyGlu: 3.27 ± 0.559
2.739GlyPhe: 2.739 ± 0.501
5.391GlyGly: 5.391 ± 1.035
0.972GlyHis: 0.972 ± 0.383
2.563GlyIle: 2.563 ± 0.595
1.944GlyLys: 1.944 ± 0.366
5.832GlyLeu: 5.832 ± 0.868
1.591GlyMet: 1.591 ± 0.314
2.739GlyAsn: 2.739 ± 0.496
3.888GlyPro: 3.888 ± 0.619
2.651GlyGln: 2.651 ± 0.396
4.772GlyArg: 4.772 ± 0.712
4.065GlySer: 4.065 ± 0.498
4.684GlyThr: 4.684 ± 0.72
5.391GlyVal: 5.391 ± 0.742
1.149GlyTrp: 1.149 ± 0.255
1.944GlyTyr: 1.944 ± 0.362
0.0GlyXaa: 0.0 ± 0.0
His
1.767HisAla: 1.767 ± 0.451
0.795HisCys: 0.795 ± 0.326
1.237HisAsp: 1.237 ± 0.363
0.972HisGlu: 0.972 ± 0.255
0.884HisPhe: 0.884 ± 0.237
2.386HisGly: 2.386 ± 0.531
1.149HisHis: 1.149 ± 0.342
1.502HisIle: 1.502 ± 0.319
0.53HisLys: 0.53 ± 0.225
2.121HisLeu: 2.121 ± 0.441
0.53HisMet: 0.53 ± 0.198
1.06HisAsn: 1.06 ± 0.261
2.209HisPro: 2.209 ± 0.494
0.795HisGln: 0.795 ± 0.277
1.767HisArg: 1.767 ± 0.302
1.326HisSer: 1.326 ± 0.3
1.149HisThr: 1.149 ± 0.249
1.856HisVal: 1.856 ± 0.489
0.265HisTrp: 0.265 ± 0.143
0.884HisTyr: 0.884 ± 0.271
0.0HisXaa: 0.0 ± 0.0
Ile
3.623IleAla: 3.623 ± 0.343
0.795IleCys: 0.795 ± 0.322
2.386IleAsp: 2.386 ± 0.403
1.679IleGlu: 1.679 ± 0.467
1.591IlePhe: 1.591 ± 0.435
3.181IleGly: 3.181 ± 0.63
1.414IleHis: 1.414 ± 0.361
1.326IleIle: 1.326 ± 0.477
1.502IleLys: 1.502 ± 0.333
2.828IleLeu: 2.828 ± 0.442
1.06IleMet: 1.06 ± 0.275
2.386IleAsn: 2.386 ± 0.412
3.005IlePro: 3.005 ± 0.537
1.767IleGln: 1.767 ± 0.399
2.651IleArg: 2.651 ± 0.44
3.005IleSer: 3.005 ± 0.507
2.386IleThr: 2.386 ± 0.461
2.386IleVal: 2.386 ± 0.515
0.442IleTrp: 0.442 ± 0.196
1.326IleTyr: 1.326 ± 0.338
0.0IleXaa: 0.0 ± 0.0
Lys
2.916LysAla: 2.916 ± 0.656
0.53LysCys: 0.53 ± 0.192
1.944LysAsp: 1.944 ± 0.292
1.237LysGlu: 1.237 ± 0.351
1.679LysPhe: 1.679 ± 0.386
2.563LysGly: 2.563 ± 0.445
0.707LysHis: 0.707 ± 0.231
1.149LysIle: 1.149 ± 0.299
2.033LysLys: 2.033 ± 0.683
3.093LysLeu: 3.093 ± 0.513
1.414LysMet: 1.414 ± 0.341
2.121LysAsn: 2.121 ± 0.519
1.502LysPro: 1.502 ± 0.427
1.502LysGln: 1.502 ± 0.35
3.005LysArg: 3.005 ± 0.619
1.502LysSer: 1.502 ± 0.462
2.739LysThr: 2.739 ± 0.49
2.209LysVal: 2.209 ± 0.428
0.265LysTrp: 0.265 ± 0.136
1.502LysTyr: 1.502 ± 0.412
0.0LysXaa: 0.0 ± 0.0
Leu
7.07LeuAla: 7.07 ± 0.786
2.033LeuCys: 2.033 ± 0.39
4.242LeuAsp: 4.242 ± 0.556
4.507LeuGlu: 4.507 ± 0.478
4.065LeuPhe: 4.065 ± 0.604
4.507LeuGly: 4.507 ± 0.802
2.033LeuHis: 2.033 ± 0.573
3.093LeuIle: 3.093 ± 0.531
4.507LeuLys: 4.507 ± 0.678
7.777LeuLeu: 7.777 ± 0.901
2.209LeuMet: 2.209 ± 0.593
3.888LeuAsn: 3.888 ± 0.567
4.949LeuPro: 4.949 ± 0.651
5.037LeuGln: 5.037 ± 0.699
7.158LeuArg: 7.158 ± 1.078
7.158LeuSer: 7.158 ± 0.635
6.981LeuThr: 6.981 ± 1.036
4.33LeuVal: 4.33 ± 0.503
1.502LeuTrp: 1.502 ± 0.336
4.153LeuTyr: 4.153 ± 0.649
0.0LeuXaa: 0.0 ± 0.0
Met
1.767MetAla: 1.767 ± 0.432
0.353MetCys: 0.353 ± 0.171
1.591MetAsp: 1.591 ± 0.403
1.679MetGlu: 1.679 ± 0.377
0.442MetPhe: 0.442 ± 0.189
1.679MetGly: 1.679 ± 0.413
0.795MetHis: 0.795 ± 0.273
0.442MetIle: 0.442 ± 0.234
0.442MetLys: 0.442 ± 0.179
2.563MetLeu: 2.563 ± 0.461
0.619MetMet: 0.619 ± 0.175
1.237MetAsn: 1.237 ± 0.359
1.06MetPro: 1.06 ± 0.329
1.06MetGln: 1.06 ± 0.279
2.209MetArg: 2.209 ± 0.473
2.121MetSer: 2.121 ± 0.445
1.767MetThr: 1.767 ± 0.336
1.856MetVal: 1.856 ± 0.482
0.265MetTrp: 0.265 ± 0.147
1.06MetTyr: 1.06 ± 0.252
0.0MetXaa: 0.0 ± 0.0
Asn
3.977AsnAla: 3.977 ± 0.586
0.53AsnCys: 0.53 ± 0.256
1.944AsnAsp: 1.944 ± 0.579
2.121AsnGlu: 2.121 ± 0.637
1.856AsnPhe: 1.856 ± 0.487
2.563AsnGly: 2.563 ± 0.612
0.53AsnHis: 0.53 ± 0.196
2.386AsnIle: 2.386 ± 0.583
1.502AsnLys: 1.502 ± 0.328
3.977AsnLeu: 3.977 ± 0.513
0.972AsnMet: 0.972 ± 0.387
1.679AsnAsn: 1.679 ± 0.403
4.419AsnPro: 4.419 ± 0.607
1.944AsnGln: 1.944 ± 0.485
2.474AsnArg: 2.474 ± 0.533
2.474AsnSer: 2.474 ± 0.813
3.623AsnThr: 3.623 ± 0.91
3.446AsnVal: 3.446 ± 0.958
0.795AsnTrp: 0.795 ± 0.253
1.679AsnTyr: 1.679 ± 0.478
0.0AsnXaa: 0.0 ± 0.0
Pro
5.479ProAla: 5.479 ± 0.781
1.414ProCys: 1.414 ± 0.472
4.419ProAsp: 4.419 ± 0.632
4.595ProGlu: 4.595 ± 0.797
2.916ProPhe: 2.916 ± 0.464
3.977ProGly: 3.977 ± 0.414
2.386ProHis: 2.386 ± 0.505
2.298ProIle: 2.298 ± 0.399
1.944ProLys: 1.944 ± 0.406
4.684ProLeu: 4.684 ± 0.636
1.502ProMet: 1.502 ± 0.444
2.828ProAsn: 2.828 ± 0.514
5.656ProPro: 5.656 ± 1.009
2.298ProGln: 2.298 ± 0.473
3.358ProArg: 3.358 ± 0.62
5.391ProSer: 5.391 ± 0.681
4.33ProThr: 4.33 ± 0.68
4.33ProVal: 4.33 ± 0.576
0.265ProTrp: 0.265 ± 0.149
2.651ProTyr: 2.651 ± 0.46
0.0ProXaa: 0.0 ± 0.0
Gln
2.563GlnAla: 2.563 ± 0.502
1.06GlnCys: 1.06 ± 0.335
1.502GlnAsp: 1.502 ± 0.357
1.767GlnGlu: 1.767 ± 0.434
1.591GlnPhe: 1.591 ± 0.31
2.474GlnGly: 2.474 ± 0.547
1.149GlnHis: 1.149 ± 0.406
1.591GlnIle: 1.591 ± 0.269
1.06GlnLys: 1.06 ± 0.282
5.125GlnLeu: 5.125 ± 0.691
1.679GlnMet: 1.679 ± 0.434
1.679GlnAsn: 1.679 ± 0.384
2.033GlnPro: 2.033 ± 0.427
3.093GlnGln: 3.093 ± 0.71
2.739GlnArg: 2.739 ± 0.506
2.474GlnSer: 2.474 ± 0.357
2.209GlnThr: 2.209 ± 0.649
2.739GlnVal: 2.739 ± 0.482
0.53GlnTrp: 0.53 ± 0.197
1.856GlnTyr: 1.856 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
5.302ArgAla: 5.302 ± 0.772
0.707ArgCys: 0.707 ± 0.262
3.535ArgAsp: 3.535 ± 0.676
3.623ArgGlu: 3.623 ± 0.605
3.093ArgPhe: 3.093 ± 0.406
4.772ArgGly: 4.772 ± 0.64
2.298ArgHis: 2.298 ± 0.574
1.856ArgIle: 1.856 ± 0.465
2.474ArgLys: 2.474 ± 0.46
6.274ArgLeu: 6.274 ± 0.789
2.033ArgMet: 2.033 ± 0.466
3.623ArgAsn: 3.623 ± 0.696
3.977ArgPro: 3.977 ± 0.616
3.446ArgGln: 3.446 ± 0.462
8.572ArgArg: 8.572 ± 1.981
4.507ArgSer: 4.507 ± 0.677
3.446ArgThr: 3.446 ± 0.491
4.33ArgVal: 4.33 ± 0.723
1.149ArgTrp: 1.149 ± 0.271
2.209ArgTyr: 2.209 ± 0.341
0.0ArgXaa: 0.0 ± 0.0
Ser
4.949SerAla: 4.949 ± 0.621
1.149SerCys: 1.149 ± 0.326
3.8SerAsp: 3.8 ± 0.534
3.712SerGlu: 3.712 ± 0.492
2.386SerPhe: 2.386 ± 0.361
6.186SerGly: 6.186 ± 1.176
1.591SerHis: 1.591 ± 0.299
3.888SerIle: 3.888 ± 0.615
1.767SerLys: 1.767 ± 0.444
5.302SerLeu: 5.302 ± 0.914
1.414SerMet: 1.414 ± 0.372
2.828SerAsn: 2.828 ± 0.649
4.772SerPro: 4.772 ± 0.756
2.563SerGln: 2.563 ± 0.545
5.302SerArg: 5.302 ± 0.764
5.567SerSer: 5.567 ± 0.916
3.8SerThr: 3.8 ± 0.508
3.888SerVal: 3.888 ± 0.539
0.707SerTrp: 0.707 ± 0.319
2.209SerTyr: 2.209 ± 0.366
0.0SerXaa: 0.0 ± 0.0
Thr
6.451ThrAla: 6.451 ± 0.921
0.972ThrCys: 0.972 ± 0.266
2.651ThrAsp: 2.651 ± 0.475
3.005ThrGlu: 3.005 ± 0.513
2.651ThrPhe: 2.651 ± 0.474
4.949ThrGly: 4.949 ± 0.635
0.972ThrHis: 0.972 ± 0.257
3.093ThrIle: 3.093 ± 0.547
2.121ThrLys: 2.121 ± 0.473
6.274ThrLeu: 6.274 ± 1.025
1.591ThrMet: 1.591 ± 0.389
3.27ThrAsn: 3.27 ± 0.927
5.302ThrPro: 5.302 ± 0.724
2.563ThrGln: 2.563 ± 0.264
3.181ThrArg: 3.181 ± 0.39
3.446ThrSer: 3.446 ± 0.68
4.153ThrThr: 4.153 ± 0.816
4.86ThrVal: 4.86 ± 0.688
0.442ThrTrp: 0.442 ± 0.181
3.005ThrTyr: 3.005 ± 0.551
0.0ThrXaa: 0.0 ± 0.0
Val
5.744ValAla: 5.744 ± 0.707
0.884ValCys: 0.884 ± 0.326
4.419ValAsp: 4.419 ± 0.464
2.651ValGlu: 2.651 ± 0.411
3.181ValPhe: 3.181 ± 0.474
3.005ValGly: 3.005 ± 0.344
1.149ValHis: 1.149 ± 0.346
2.563ValIle: 2.563 ± 0.42
2.916ValLys: 2.916 ± 0.424
6.451ValLeu: 6.451 ± 0.727
1.06ValMet: 1.06 ± 0.298
2.916ValAsn: 2.916 ± 0.771
4.595ValPro: 4.595 ± 0.693
2.209ValGln: 2.209 ± 0.528
4.065ValArg: 4.065 ± 0.543
4.684ValSer: 4.684 ± 0.719
5.214ValThr: 5.214 ± 0.759
4.772ValVal: 4.772 ± 0.706
0.972ValTrp: 0.972 ± 0.274
1.944ValTyr: 1.944 ± 0.315
0.0ValXaa: 0.0 ± 0.0
Trp
0.884TrpAla: 0.884 ± 0.299
0.53TrpCys: 0.53 ± 0.207
0.53TrpAsp: 0.53 ± 0.21
0.972TrpGlu: 0.972 ± 0.247
0.53TrpPhe: 0.53 ± 0.211
0.619TrpGly: 0.619 ± 0.224
0.088TrpHis: 0.088 ± 0.099
0.353TrpIle: 0.353 ± 0.154
0.442TrpLys: 0.442 ± 0.256
0.884TrpLeu: 0.884 ± 0.171
0.177TrpMet: 0.177 ± 0.174
0.707TrpAsn: 0.707 ± 0.202
0.619TrpPro: 0.619 ± 0.414
0.619TrpGln: 0.619 ± 0.201
1.237TrpArg: 1.237 ± 0.316
0.884TrpSer: 0.884 ± 0.248
1.237TrpThr: 1.237 ± 0.341
1.149TrpVal: 1.149 ± 0.29
0.177TrpTrp: 0.177 ± 0.11
0.442TrpTyr: 0.442 ± 0.19
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.093TyrAla: 3.093 ± 0.532
0.707TyrCys: 0.707 ± 0.198
2.651TyrAsp: 2.651 ± 0.505
1.679TyrGlu: 1.679 ± 0.452
2.298TyrPhe: 2.298 ± 0.589
1.944TyrGly: 1.944 ± 0.413
1.149TyrHis: 1.149 ± 0.238
0.619TyrIle: 0.619 ± 0.259
1.326TyrLys: 1.326 ± 0.391
3.446TyrLeu: 3.446 ± 0.528
1.237TyrMet: 1.237 ± 0.368
1.944TyrAsn: 1.944 ± 0.412
2.209TyrPro: 2.209 ± 0.443
1.502TyrGln: 1.502 ± 0.354
2.386TyrArg: 2.386 ± 0.518
2.386TyrSer: 2.386 ± 0.357
2.121TyrThr: 2.121 ± 0.54
2.386TyrVal: 2.386 ± 0.361
0.619TyrTrp: 0.619 ± 0.273
1.06TyrTyr: 1.06 ± 0.21
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 33 proteins (11317 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski