Amino acid dipepetide frequency for Human adenovirus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.516AlaAla: 7.516 ± 1.246
1.762AlaCys: 1.762 ± 0.684
2.349AlaAsp: 2.349 ± 0.463
3.523AlaGlu: 3.523 ± 0.536
2.584AlaPhe: 2.584 ± 0.471
4.345AlaGly: 4.345 ± 0.73
1.644AlaHis: 1.644 ± 0.438
3.171AlaIle: 3.171 ± 0.576
2.114AlaLys: 2.114 ± 0.463
7.281AlaLeu: 7.281 ± 1.137
0.94AlaMet: 0.94 ± 0.399
4.11AlaAsn: 4.11 ± 0.546
4.698AlaPro: 4.698 ± 0.759
1.996AlaGln: 1.996 ± 0.41
3.523AlaArg: 3.523 ± 0.541
4.932AlaSer: 4.932 ± 0.458
4.463AlaThr: 4.463 ± 0.698
4.815AlaVal: 4.815 ± 0.718
0.587AlaTrp: 0.587 ± 0.232
2.231AlaTyr: 2.231 ± 0.448
0.0AlaXaa: 0.0 ± 0.0
Cys
1.644CysAla: 1.644 ± 0.521
1.057CysCys: 1.057 ± 0.395
1.057CysAsp: 1.057 ± 0.317
0.94CysGlu: 0.94 ± 0.257
0.587CysPhe: 0.587 ± 0.247
1.996CysGly: 1.996 ± 0.555
0.822CysHis: 0.822 ± 0.286
0.822CysIle: 0.822 ± 0.347
0.587CysLys: 0.587 ± 0.199
1.762CysLeu: 1.762 ± 0.582
0.822CysMet: 0.822 ± 0.41
1.527CysAsn: 1.527 ± 0.643
0.822CysPro: 0.822 ± 0.264
0.117CysGln: 0.117 ± 0.111
0.705CysArg: 0.705 ± 0.281
0.587CysSer: 0.587 ± 0.231
0.94CysThr: 0.94 ± 0.343
1.292CysVal: 1.292 ± 0.431
0.47CysTrp: 0.47 ± 0.263
1.174CysTyr: 1.174 ± 0.304
0.0CysXaa: 0.0 ± 0.0
Asp
3.053AspAla: 3.053 ± 0.624
0.94AspCys: 0.94 ± 0.351
2.349AspAsp: 2.349 ± 0.542
4.58AspGlu: 4.58 ± 0.534
1.292AspPhe: 1.292 ± 0.304
3.523AspGly: 3.523 ± 0.533
1.174AspHis: 1.174 ± 0.444
2.819AspIle: 2.819 ± 0.507
1.996AspLys: 1.996 ± 0.327
5.167AspLeu: 5.167 ± 1.015
2.231AspMet: 2.231 ± 0.387
2.231AspAsn: 2.231 ± 0.493
4.228AspPro: 4.228 ± 0.677
1.174AspGln: 1.174 ± 0.351
3.876AspArg: 3.876 ± 0.882
3.523AspSer: 3.523 ± 0.545
2.466AspThr: 2.466 ± 0.672
2.936AspVal: 2.936 ± 0.439
0.47AspTrp: 0.47 ± 0.202
1.879AspTyr: 1.879 ± 0.404
0.0AspXaa: 0.0 ± 0.0
Glu
4.228GluAla: 4.228 ± 0.962
1.057GluCys: 1.057 ± 0.4
4.345GluAsp: 4.345 ± 0.574
6.694GluGlu: 6.694 ± 1.299
1.879GluPhe: 1.879 ± 0.468
4.58GluGly: 4.58 ± 0.881
1.057GluHis: 1.057 ± 0.372
2.349GluIle: 2.349 ± 0.568
3.523GluLys: 3.523 ± 0.708
5.637GluLeu: 5.637 ± 1.025
1.174GluMet: 1.174 ± 0.423
3.523GluAsn: 3.523 ± 0.63
2.584GluPro: 2.584 ± 0.461
2.936GluGln: 2.936 ± 0.439
3.523GluArg: 3.523 ± 0.563
3.053GluSer: 3.053 ± 0.718
3.406GluThr: 3.406 ± 0.651
4.698GluVal: 4.698 ± 0.775
0.705GluTrp: 0.705 ± 0.378
1.527GluTyr: 1.527 ± 0.456
0.0GluXaa: 0.0 ± 0.0
Phe
1.996PheAla: 1.996 ± 0.359
0.352PheCys: 0.352 ± 0.196
3.053PheAsp: 3.053 ± 0.506
1.644PheGlu: 1.644 ± 0.313
1.644PhePhe: 1.644 ± 0.45
1.292PheGly: 1.292 ± 0.33
0.94PheHis: 0.94 ± 0.294
1.644PheIle: 1.644 ± 0.402
2.349PheLys: 2.349 ± 0.561
3.758PheLeu: 3.758 ± 0.732
1.527PheMet: 1.527 ± 0.295
2.231PheAsn: 2.231 ± 0.558
2.466PhePro: 2.466 ± 0.431
1.527PheGln: 1.527 ± 0.36
2.231PheArg: 2.231 ± 0.381
2.819PheSer: 2.819 ± 0.46
2.936PheThr: 2.936 ± 0.536
1.996PheVal: 1.996 ± 0.327
0.0PheTrp: 0.0 ± 0.0
1.996PheTyr: 1.996 ± 0.363
0.0PheXaa: 0.0 ± 0.0
Gly
4.463GlyAla: 4.463 ± 0.563
1.879GlyCys: 1.879 ± 0.505
2.466GlyAsp: 2.466 ± 0.481
3.876GlyGlu: 3.876 ± 0.695
2.819GlyPhe: 2.819 ± 0.498
5.05GlyGly: 5.05 ± 1.002
1.527GlyHis: 1.527 ± 0.444
3.053GlyIle: 3.053 ± 0.412
2.114GlyLys: 2.114 ± 0.553
5.872GlyLeu: 5.872 ± 0.795
1.644GlyMet: 1.644 ± 0.645
2.701GlyAsn: 2.701 ± 0.735
2.349GlyPro: 2.349 ± 0.561
2.819GlyGln: 2.819 ± 0.603
3.758GlyArg: 3.758 ± 0.533
4.228GlySer: 4.228 ± 0.601
3.993GlyThr: 3.993 ± 0.586
4.228GlyVal: 4.228 ± 0.884
0.822GlyTrp: 0.822 ± 0.266
1.527GlyTyr: 1.527 ± 0.366
0.0GlyXaa: 0.0 ± 0.0
His
1.879HisAla: 1.879 ± 0.522
1.174HisCys: 1.174 ± 0.444
0.822HisAsp: 0.822 ± 0.209
1.292HisGlu: 1.292 ± 0.465
0.705HisPhe: 0.705 ± 0.304
1.644HisGly: 1.644 ± 0.34
0.705HisHis: 0.705 ± 0.177
0.94HisIle: 0.94 ± 0.254
1.057HisLys: 1.057 ± 0.314
1.996HisLeu: 1.996 ± 0.437
0.117HisMet: 0.117 ± 0.126
1.409HisAsn: 1.409 ± 0.324
1.996HisPro: 1.996 ± 0.484
0.705HisGln: 0.705 ± 0.21
1.996HisArg: 1.996 ± 0.487
2.114HisSer: 2.114 ± 0.478
0.587HisThr: 0.587 ± 0.172
0.94HisVal: 0.94 ± 0.292
0.47HisTrp: 0.47 ± 0.269
0.47HisTyr: 0.47 ± 0.179
0.0HisXaa: 0.0 ± 0.0
Ile
3.288IleAla: 3.288 ± 0.724
0.822IleCys: 0.822 ± 0.268
1.292IleAsp: 1.292 ± 0.338
1.762IleGlu: 1.762 ± 0.363
1.996IlePhe: 1.996 ± 0.579
2.466IleGly: 2.466 ± 0.638
0.705IleHis: 0.705 ± 0.239
2.349IleIle: 2.349 ± 0.546
2.584IleLys: 2.584 ± 0.585
3.523IleLeu: 3.523 ± 0.687
1.996IleMet: 1.996 ± 0.726
2.701IleAsn: 2.701 ± 0.702
3.288IlePro: 3.288 ± 0.661
1.996IleGln: 1.996 ± 0.536
2.466IleArg: 2.466 ± 0.496
2.819IleSer: 2.819 ± 0.44
2.701IleThr: 2.701 ± 0.484
3.288IleVal: 3.288 ± 0.606
0.352IleTrp: 0.352 ± 0.24
1.174IleTyr: 1.174 ± 0.289
0.0IleXaa: 0.0 ± 0.0
Lys
2.701LysAla: 2.701 ± 0.484
1.057LysCys: 1.057 ± 0.312
2.584LysAsp: 2.584 ± 0.501
2.819LysGlu: 2.819 ± 0.396
1.644LysPhe: 1.644 ± 0.411
2.701LysGly: 2.701 ± 0.766
0.587LysHis: 0.587 ± 0.286
3.523LysIle: 3.523 ± 0.512
2.936LysLys: 2.936 ± 0.54
4.11LysLeu: 4.11 ± 0.848
1.527LysMet: 1.527 ± 0.527
2.231LysAsn: 2.231 ± 0.279
2.819LysPro: 2.819 ± 0.761
1.527LysGln: 1.527 ± 0.39
2.936LysArg: 2.936 ± 0.917
2.114LysSer: 2.114 ± 0.417
2.584LysThr: 2.584 ± 0.569
2.819LysVal: 2.819 ± 0.434
0.587LysTrp: 0.587 ± 0.212
1.762LysTyr: 1.762 ± 0.509
0.0LysXaa: 0.0 ± 0.0
Leu
5.637LeuAla: 5.637 ± 0.856
1.879LeuCys: 1.879 ± 0.603
4.698LeuAsp: 4.698 ± 0.74
6.342LeuGlu: 6.342 ± 0.986
2.349LeuPhe: 2.349 ± 0.539
6.342LeuGly: 6.342 ± 0.698
2.466LeuHis: 2.466 ± 0.529
2.819LeuIle: 2.819 ± 0.549
5.05LeuLys: 5.05 ± 0.821
9.278LeuLeu: 9.278 ± 1.374
3.523LeuMet: 3.523 ± 0.606
4.463LeuAsn: 4.463 ± 0.605
5.52LeuPro: 5.52 ± 0.748
3.758LeuGln: 3.758 ± 0.551
6.224LeuArg: 6.224 ± 0.569
5.872LeuSer: 5.872 ± 0.577
5.989LeuThr: 5.989 ± 0.999
6.224LeuVal: 6.224 ± 0.787
1.879LeuTrp: 1.879 ± 0.34
3.523LeuTyr: 3.523 ± 0.747
0.0LeuXaa: 0.0 ± 0.0
Met
2.349MetAla: 2.349 ± 0.466
0.587MetCys: 0.587 ± 0.221
1.644MetAsp: 1.644 ± 0.422
1.762MetGlu: 1.762 ± 0.387
1.292MetPhe: 1.292 ± 0.353
1.996MetGly: 1.996 ± 0.419
1.762MetHis: 1.762 ± 0.629
1.292MetIle: 1.292 ± 0.492
0.94MetLys: 0.94 ± 0.254
2.819MetLeu: 2.819 ± 0.636
0.94MetMet: 0.94 ± 0.317
0.94MetAsn: 0.94 ± 0.324
2.466MetPro: 2.466 ± 0.469
1.996MetGln: 1.996 ± 0.444
1.527MetArg: 1.527 ± 0.567
1.527MetSer: 1.527 ± 0.398
1.762MetThr: 1.762 ± 0.416
1.057MetVal: 1.057 ± 0.299
0.47MetTrp: 0.47 ± 0.244
0.822MetTyr: 0.822 ± 0.282
0.0MetXaa: 0.0 ± 0.0
Asn
3.053AsnAla: 3.053 ± 0.576
0.587AsnCys: 0.587 ± 0.226
2.231AsnAsp: 2.231 ± 0.52
2.466AsnGlu: 2.466 ± 0.517
3.288AsnPhe: 3.288 ± 0.666
2.466AsnGly: 2.466 ± 0.563
0.94AsnHis: 0.94 ± 0.34
2.819AsnIle: 2.819 ± 0.655
1.879AsnLys: 1.879 ± 0.389
4.228AsnLeu: 4.228 ± 0.699
2.466AsnMet: 2.466 ± 0.676
2.819AsnAsn: 2.819 ± 0.699
3.641AsnPro: 3.641 ± 0.551
1.762AsnGln: 1.762 ± 0.343
2.936AsnArg: 2.936 ± 0.527
3.288AsnSer: 3.288 ± 0.767
3.053AsnThr: 3.053 ± 0.678
1.996AsnVal: 1.996 ± 0.596
1.057AsnTrp: 1.057 ± 0.366
2.819AsnTyr: 2.819 ± 0.553
0.0AsnXaa: 0.0 ± 0.0
Pro
3.876ProAla: 3.876 ± 0.6
0.587ProCys: 0.587 ± 0.243
4.345ProAsp: 4.345 ± 0.619
5.05ProGlu: 5.05 ± 0.478
3.053ProPhe: 3.053 ± 0.658
4.228ProGly: 4.228 ± 0.587
1.057ProHis: 1.057 ± 0.349
2.466ProIle: 2.466 ± 0.561
2.466ProLys: 2.466 ± 0.602
4.228ProLeu: 4.228 ± 0.58
1.292ProMet: 1.292 ± 0.372
2.936ProAsn: 2.936 ± 0.551
4.345ProPro: 4.345 ± 1.066
2.819ProGln: 2.819 ± 0.473
4.228ProArg: 4.228 ± 0.961
4.345ProSer: 4.345 ± 0.623
4.698ProThr: 4.698 ± 0.897
4.11ProVal: 4.11 ± 0.649
0.705ProTrp: 0.705 ± 0.323
2.466ProTyr: 2.466 ± 0.518
0.0ProXaa: 0.0 ± 0.0
Gln
2.936GlnAla: 2.936 ± 0.406
0.587GlnCys: 0.587 ± 0.224
2.349GlnAsp: 2.349 ± 0.401
2.584GlnGlu: 2.584 ± 0.479
1.292GlnPhe: 1.292 ± 0.364
1.644GlnGly: 1.644 ± 0.266
1.174GlnHis: 1.174 ± 0.299
1.409GlnIle: 1.409 ± 0.393
2.349GlnLys: 2.349 ± 0.519
4.58GlnLeu: 4.58 ± 0.676
1.292GlnMet: 1.292 ± 0.31
1.762GlnAsn: 1.762 ± 0.495
3.523GlnPro: 3.523 ± 0.512
3.288GlnGln: 3.288 ± 0.795
2.936GlnArg: 2.936 ± 0.577
3.876GlnSer: 3.876 ± 0.774
2.701GlnThr: 2.701 ± 0.566
2.466GlnVal: 2.466 ± 0.465
0.705GlnTrp: 0.705 ± 0.246
0.94GlnTyr: 0.94 ± 0.354
0.0GlnXaa: 0.0 ± 0.0
Arg
5.285ArgAla: 5.285 ± 0.861
1.527ArgCys: 1.527 ± 0.486
2.466ArgAsp: 2.466 ± 0.636
3.876ArgGlu: 3.876 ± 0.815
1.879ArgPhe: 1.879 ± 0.393
4.345ArgGly: 4.345 ± 0.579
1.762ArgHis: 1.762 ± 0.511
2.349ArgIle: 2.349 ± 0.536
2.936ArgLys: 2.936 ± 0.616
4.58ArgLeu: 4.58 ± 0.531
1.409ArgMet: 1.409 ± 0.386
3.641ArgAsn: 3.641 ± 0.473
3.758ArgPro: 3.758 ± 0.877
3.758ArgGln: 3.758 ± 0.66
4.58ArgArg: 4.58 ± 1.282
5.872ArgSer: 5.872 ± 0.959
3.641ArgThr: 3.641 ± 0.606
3.171ArgVal: 3.171 ± 0.674
0.94ArgTrp: 0.94 ± 0.173
1.762ArgTyr: 1.762 ± 0.423
0.0ArgXaa: 0.0 ± 0.0
Ser
4.345SerAla: 4.345 ± 0.615
0.94SerCys: 0.94 ± 0.303
3.406SerAsp: 3.406 ± 0.441
3.288SerGlu: 3.288 ± 0.433
3.053SerPhe: 3.053 ± 0.647
3.523SerGly: 3.523 ± 0.57
1.527SerHis: 1.527 ± 0.46
3.406SerIle: 3.406 ± 0.621
2.349SerLys: 2.349 ± 0.64
7.516SerLeu: 7.516 ± 0.852
1.644SerMet: 1.644 ± 0.491
3.288SerAsn: 3.288 ± 0.733
3.406SerPro: 3.406 ± 0.579
3.641SerGln: 3.641 ± 0.499
6.107SerArg: 6.107 ± 0.945
5.637SerSer: 5.637 ± 0.895
3.993SerThr: 3.993 ± 0.681
4.463SerVal: 4.463 ± 0.532
0.705SerTrp: 0.705 ± 0.302
2.584SerTyr: 2.584 ± 0.473
0.0SerXaa: 0.0 ± 0.0
Thr
4.228ThrAla: 4.228 ± 0.836
1.292ThrCys: 1.292 ± 0.439
2.936ThrAsp: 2.936 ± 0.475
2.936ThrGlu: 2.936 ± 0.482
3.641ThrPhe: 3.641 ± 0.605
3.758ThrGly: 3.758 ± 0.88
1.292ThrHis: 1.292 ± 0.33
1.762ThrIle: 1.762 ± 0.55
2.231ThrLys: 2.231 ± 0.481
6.342ThrLeu: 6.342 ± 0.913
1.762ThrMet: 1.762 ± 0.422
1.996ThrAsn: 1.996 ± 0.458
4.815ThrPro: 4.815 ± 0.641
1.762ThrGln: 1.762 ± 0.396
3.641ThrArg: 3.641 ± 0.577
4.11ThrSer: 4.11 ± 0.708
4.698ThrThr: 4.698 ± 1.098
4.698ThrVal: 4.698 ± 0.493
1.057ThrTrp: 1.057 ± 0.307
2.701ThrTyr: 2.701 ± 0.524
0.0ThrXaa: 0.0 ± 0.0
Val
3.406ValAla: 3.406 ± 0.585
0.587ValCys: 0.587 ± 0.289
4.228ValAsp: 4.228 ± 0.64
3.523ValGlu: 3.523 ± 0.818
1.527ValPhe: 1.527 ± 0.299
2.584ValGly: 2.584 ± 0.559
0.705ValHis: 0.705 ± 0.272
2.701ValIle: 2.701 ± 0.643
3.288ValLys: 3.288 ± 0.442
6.459ValLeu: 6.459 ± 0.867
2.114ValMet: 2.114 ± 0.398
3.053ValAsn: 3.053 ± 0.562
3.523ValPro: 3.523 ± 0.501
3.876ValGln: 3.876 ± 0.73
3.758ValArg: 3.758 ± 0.428
4.345ValSer: 4.345 ± 0.516
3.758ValThr: 3.758 ± 0.606
3.758ValVal: 3.758 ± 0.662
0.705ValTrp: 0.705 ± 0.249
3.288ValTyr: 3.288 ± 0.528
0.0ValXaa: 0.0 ± 0.0
Trp
0.352TrpAla: 0.352 ± 0.19
0.0TrpCys: 0.0 ± 0.0
0.587TrpAsp: 0.587 ± 0.222
1.292TrpGlu: 1.292 ± 0.375
0.47TrpPhe: 0.47 ± 0.211
0.705TrpGly: 0.705 ± 0.201
0.117TrpHis: 0.117 ± 0.115
0.47TrpIle: 0.47 ± 0.168
0.94TrpLys: 0.94 ± 0.328
0.822TrpLeu: 0.822 ± 0.217
0.235TrpMet: 0.235 ± 0.138
0.822TrpAsn: 0.822 ± 0.34
0.822TrpPro: 0.822 ± 0.306
1.057TrpGln: 1.057 ± 0.439
0.47TrpArg: 0.47 ± 0.235
1.762TrpSer: 1.762 ± 0.458
1.057TrpThr: 1.057 ± 0.269
0.47TrpVal: 0.47 ± 0.228
0.235TrpTrp: 0.235 ± 0.132
0.587TrpTyr: 0.587 ± 0.334
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.349TyrAla: 2.349 ± 0.574
1.057TyrCys: 1.057 ± 0.407
2.819TyrAsp: 2.819 ± 0.457
2.231TyrGlu: 2.231 ± 0.531
1.409TyrPhe: 1.409 ± 0.423
1.996TyrGly: 1.996 ± 0.469
1.057TyrHis: 1.057 ± 0.522
1.409TyrIle: 1.409 ± 0.345
1.879TyrLys: 1.879 ± 0.577
3.876TyrLeu: 3.876 ± 0.702
1.174TyrMet: 1.174 ± 0.295
1.409TyrAsn: 1.409 ± 0.51
2.231TyrPro: 2.231 ± 0.456
1.879TyrGln: 1.879 ± 0.499
2.114TyrArg: 2.114 ± 0.398
1.996TyrSer: 1.996 ± 0.509
2.231TyrThr: 2.231 ± 0.339
1.762TyrVal: 1.762 ± 0.288
0.352TyrTrp: 0.352 ± 0.141
0.587TyrTyr: 0.587 ± 0.183
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 27 proteins (8516 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski