Amino acid dipepetide frequency for Thermasporomyces composti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.56AlaAla: 17.56 ± 0.187	1.06AlaCys: 1.06 ± 0.031	7.361AlaAsp: 7.361 ± 0.082	8.125AlaGlu: 8.125 ± 0.092	3.617AlaPhe: 3.617 ± 0.057	11.019AlaGly: 11.019 ± 0.099	2.501AlaHis: 2.501 ± 0.051	4.447AlaIle: 4.447 ± 0.068	2.497AlaLys: 2.497 ± 0.054	12.879AlaLeu: 12.879 ± 0.134	2.414AlaMet: 2.414 ± 0.041	2.075AlaAsn: 2.075 ± 0.041	5.806AlaPro: 5.806 ± 0.076	3.257AlaGln: 3.257 ± 0.053	10.946AlaArg: 10.946 ± 0.116	6.361AlaSer: 6.361 ± 0.078	7.391AlaThr: 7.391 ± 0.084	11.409AlaVal: 11.409 ± 0.112	2.05AlaTrp: 2.05 ± 0.042	2.716AlaTyr: 2.716 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.956CysAla: 0.956 ± 0.034	0.102CysCys: 0.102 ± 0.009	0.511CysAsp: 0.511 ± 0.019	0.442CysGlu: 0.442 ± 0.017	0.227CysPhe: 0.227 ± 0.014	0.92CysGly: 0.92 ± 0.028	0.219CysHis: 0.219 ± 0.013	0.154CysIle: 0.154 ± 0.012	0.094CysLys: 0.094 ± 0.008	0.714CysLeu: 0.714 ± 0.023	0.093CysMet: 0.093 ± 0.009	0.118CysAsn: 0.118 ± 0.009	0.524CysPro: 0.524 ± 0.021	0.206CysGln: 0.206 ± 0.014	0.636CysArg: 0.636 ± 0.02	0.347CysSer: 0.347 ± 0.015	0.388CysThr: 0.388 ± 0.017	0.783CysVal: 0.783 ± 0.023	0.143CysTrp: 0.143 ± 0.01	0.192CysTyr: 0.192 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.127AspAla: 7.127 ± 0.091	0.338AspCys: 0.338 ± 0.015	4.023AspAsp: 4.023 ± 0.054	4.242AspGlu: 4.242 ± 0.057	1.495AspPhe: 1.495 ± 0.037	5.992AspGly: 5.992 ± 0.092	1.383AspHis: 1.383 ± 0.032	2.009AspIle: 2.009 ± 0.045	0.961AspLys: 0.961 ± 0.029	6.616AspLeu: 6.616 ± 0.064	0.755AspMet: 0.755 ± 0.023	0.881AspAsn: 0.881 ± 0.028	4.885AspPro: 4.885 ± 0.063	1.859AspGln: 1.859 ± 0.04	4.918AspArg: 4.918 ± 0.066	2.235AspSer: 2.235 ± 0.04	2.826AspThr: 2.826 ± 0.05	5.986AspVal: 5.986 ± 0.086	0.9AspTrp: 0.9 ± 0.028	1.274AspTyr: 1.274 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.14GluAla: 7.14 ± 0.091	0.373GluCys: 0.373 ± 0.015	2.779GluAsp: 2.779 ± 0.05	3.874GluGlu: 3.874 ± 0.063	1.525GluPhe: 1.525 ± 0.038	4.215GluGly: 4.215 ± 0.06	1.411GluHis: 1.411 ± 0.032	2.493GluIle: 2.493 ± 0.054	1.31GluLys: 1.31 ± 0.035	6.697GluLeu: 6.697 ± 0.085	0.909GluMet: 0.909 ± 0.028	1.051GluAsn: 1.051 ± 0.03	3.807GluPro: 3.807 ± 0.058	2.049GluGln: 2.049 ± 0.042	6.574GluArg: 6.574 ± 0.089	2.542GluSer: 2.542 ± 0.043	2.928GluThr: 2.928 ± 0.059	5.478GluVal: 5.478 ± 0.071	0.889GluTrp: 0.889 ± 0.029	1.218GluTyr: 1.218 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.536PheAla: 3.536 ± 0.057	0.293PheCys: 0.293 ± 0.016	2.102PheAsp: 2.102 ± 0.044	1.517PheGlu: 1.517 ± 0.032	0.938PhePhe: 0.938 ± 0.033	2.906PheGly: 2.906 ± 0.05	0.663PheHis: 0.663 ± 0.026	0.821PheIle: 0.821 ± 0.023	0.376PheLys: 0.376 ± 0.019	2.728PheLeu: 2.728 ± 0.059	0.353PheMet: 0.353 ± 0.017	0.549PheAsn: 0.549 ± 0.023	1.376PhePro: 1.376 ± 0.035	0.735PheGln: 0.735 ± 0.025	2.033PheArg: 2.033 ± 0.04	1.345PheSer: 1.345 ± 0.034	1.87PheThr: 1.87 ± 0.037	2.737PheVal: 2.737 ± 0.048	0.477PheTrp: 0.477 ± 0.024	0.671PheTyr: 0.671 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.259GlyAla: 9.259 ± 0.091	0.818GlyCys: 0.818 ± 0.023	4.758GlyAsp: 4.758 ± 0.067	5.069GlyGlu: 5.069 ± 0.071	2.745GlyPhe: 2.745 ± 0.047	7.432GlyGly: 7.432 ± 0.093	1.975GlyHis: 1.975 ± 0.043	3.364GlyIle: 3.364 ± 0.058	1.921GlyLys: 1.921 ± 0.041	8.862GlyLeu: 8.862 ± 0.098	1.794GlyMet: 1.794 ± 0.037	1.387GlyAsn: 1.387 ± 0.033	4.805GlyPro: 4.805 ± 0.065	2.539GlyGln: 2.539 ± 0.05	7.708GlyArg: 7.708 ± 0.077	4.779GlySer: 4.779 ± 0.068	5.337GlyThr: 5.337 ± 0.063	8.368GlyVal: 8.368 ± 0.09	1.706GlyTrp: 1.706 ± 0.038	2.328GlyTyr: 2.328 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.586HisAla: 2.586 ± 0.048	0.165HisCys: 0.165 ± 0.012	1.424HisAsp: 1.424 ± 0.034	1.234HisGlu: 1.234 ± 0.033	0.532HisPhe: 0.532 ± 0.022	2.124HisGly: 2.124 ± 0.041	0.607HisHis: 0.607 ± 0.022	0.635HisIle: 0.635 ± 0.022	0.301HisLys: 0.301 ± 0.013	2.322HisLeu: 2.322 ± 0.042	0.297HisMet: 0.297 ± 0.016	0.393HisAsn: 0.393 ± 0.018	1.703HisPro: 1.703 ± 0.037	0.67HisGln: 0.67 ± 0.024	1.901HisArg: 1.901 ± 0.042	0.772HisSer: 0.772 ± 0.023	1.105HisThr: 1.105 ± 0.031	1.957HisVal: 1.957 ± 0.043	0.336HisTrp: 0.336 ± 0.015	0.51HisTyr: 0.51 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	4.706IleAla: 4.706 ± 0.066	0.336IleCys: 0.336 ± 0.016	2.539IleAsp: 2.539 ± 0.051	2.267IleGlu: 2.267 ± 0.045	0.913IlePhe: 0.913 ± 0.029	3.331IleGly: 3.331 ± 0.06	0.689IleHis: 0.689 ± 0.022	1.103IleIle: 1.103 ± 0.04	0.658IleLys: 0.658 ± 0.025	3.019IleLeu: 3.019 ± 0.048	0.442IleMet: 0.442 ± 0.02	0.717IleAsn: 0.717 ± 0.025	2.062IlePro: 2.062 ± 0.041	0.807IleGln: 0.807 ± 0.03	2.911IleArg: 2.911 ± 0.046	1.594IleSer: 1.594 ± 0.038	2.047IleThr: 2.047 ± 0.046	3.43IleVal: 3.43 ± 0.055	0.42IleTrp: 0.42 ± 0.019	0.719IleTyr: 0.719 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.314LysAla: 2.314 ± 0.049	0.082LysCys: 0.082 ± 0.009	1.046LysAsp: 1.046 ± 0.025	1.103LysGlu: 1.103 ± 0.035	0.369LysPhe: 0.369 ± 0.018	1.483LysGly: 1.483 ± 0.037	0.359LysHis: 0.359 ± 0.017	0.736LysIle: 0.736 ± 0.028	0.485LysLys: 0.485 ± 0.027	1.772LysLeu: 1.772 ± 0.041	0.255LysMet: 0.255 ± 0.017	0.393LysAsn: 0.393 ± 0.02	1.235LysPro: 1.235 ± 0.032	0.535LysGln: 0.535 ± 0.02	1.401LysArg: 1.401 ± 0.036	0.84LysSer: 0.84 ± 0.028	1.027LysThr: 1.027 ± 0.032	1.91LysVal: 1.91 ± 0.038	0.192LysTrp: 0.192 ± 0.012	0.393LysTyr: 0.393 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	15.423LeuAla: 15.423 ± 0.163	0.782LeuCys: 0.782 ± 0.028	6.875LeuAsp: 6.875 ± 0.079	5.308LeuGlu: 5.308 ± 0.082	2.556LeuPhe: 2.556 ± 0.054	8.961LeuGly: 8.961 ± 0.094	1.947LeuHis: 1.947 ± 0.041	3.126LeuIle: 3.126 ± 0.054	1.415LeuLys: 1.415 ± 0.045	10.862LeuLeu: 10.862 ± 0.131	1.344LeuMet: 1.344 ± 0.035	1.628LeuAsn: 1.628 ± 0.035	6.221LeuPro: 6.221 ± 0.072	2.123LeuGln: 2.123 ± 0.043	9.416LeuArg: 9.416 ± 0.086	5.121LeuSer: 5.121 ± 0.065	6.356LeuThr: 6.356 ± 0.078	10.34LeuVal: 10.34 ± 0.122	1.325LeuTrp: 1.325 ± 0.033	1.884LeuTyr: 1.884 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.163MetAla: 2.163 ± 0.041	0.117MetCys: 0.117 ± 0.01	0.73MetAsp: 0.73 ± 0.027	0.711MetGlu: 0.711 ± 0.027	0.415MetPhe: 0.415 ± 0.021	1.183MetGly: 1.183 ± 0.034	0.286MetHis: 0.286 ± 0.017	0.587MetIle: 0.587 ± 0.019	0.334MetLys: 0.334 ± 0.017	1.672MetLeu: 1.672 ± 0.035	0.231MetMet: 0.231 ± 0.013	0.349MetAsn: 0.349 ± 0.016	1.112MetPro: 1.112 ± 0.028	0.326MetGln: 0.326 ± 0.015	1.596MetArg: 1.596 ± 0.035	1.236MetSer: 1.236 ± 0.029	1.428MetThr: 1.428 ± 0.03	1.448MetVal: 1.448 ± 0.035	0.215MetTrp: 0.215 ± 0.012	0.314MetTyr: 0.314 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.146AsnAla: 2.146 ± 0.039	0.126AsnCys: 0.126 ± 0.011	0.939AsnAsp: 0.939 ± 0.027	0.859AsnGlu: 0.859 ± 0.026	0.492AsnPhe: 0.492 ± 0.023	1.612AsnGly: 1.612 ± 0.039	0.363AsnHis: 0.363 ± 0.017	0.601AsnIle: 0.601 ± 0.024	0.331AsnLys: 0.331 ± 0.018	1.835AsnLeu: 1.835 ± 0.042	0.23AsnMet: 0.23 ± 0.014	0.38AsnAsn: 0.38 ± 0.016	1.565AsnPro: 1.565 ± 0.033	0.555AsnGln: 0.555 ± 0.023	1.245AsnArg: 1.245 ± 0.029	0.692AsnSer: 0.692 ± 0.026	0.913AsnThr: 0.913 ± 0.028	1.638AsnVal: 1.638 ± 0.035	0.256AsnTrp: 0.256 ± 0.016	0.44AsnTyr: 0.44 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.042ProAla: 7.042 ± 0.091	0.342ProCys: 0.342 ± 0.017	4.851ProAsp: 4.851 ± 0.064	4.358ProGlu: 4.358 ± 0.066	1.655ProPhe: 1.655 ± 0.038	5.795ProGly: 5.795 ± 0.076	1.449ProHis: 1.449 ± 0.04	1.859ProIle: 1.859 ± 0.039	1.089ProLys: 1.089 ± 0.034	5.268ProLeu: 5.268 ± 0.074	0.984ProMet: 0.984 ± 0.027	1.111ProAsn: 1.111 ± 0.027	3.958ProPro: 3.958 ± 0.079	1.404ProGln: 1.404 ± 0.033	4.78ProArg: 4.78 ± 0.065	3.639ProSer: 3.639 ± 0.058	4.275ProThr: 4.275 ± 0.073	5.352ProVal: 5.352 ± 0.068	1.031ProTrp: 1.031 ± 0.029	1.503ProTyr: 1.503 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.56GlnAla: 3.56 ± 0.057	0.14GlnCys: 0.14 ± 0.01	1.081GlnAsp: 1.081 ± 0.031	1.394GlnGlu: 1.394 ± 0.033	0.668GlnPhe: 0.668 ± 0.021	1.813GlnGly: 1.813 ± 0.041	0.588GlnHis: 0.588 ± 0.02	1.129GlnIle: 1.129 ± 0.03	0.48GlnLys: 0.48 ± 0.021	2.975GlnLeu: 2.975 ± 0.054	0.452GlnMet: 0.452 ± 0.02	0.428GlnAsn: 0.428 ± 0.019	1.812GlnPro: 1.812 ± 0.039	0.984GlnGln: 0.984 ± 0.031	2.811GlnArg: 2.811 ± 0.05	1.086GlnSer: 1.086 ± 0.028	1.371GlnThr: 1.371 ± 0.033	2.68GlnVal: 2.68 ± 0.042	0.468GlnTrp: 0.468 ± 0.02	0.569GlnTyr: 0.569 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	10.362ArgAla: 10.362 ± 0.104	0.671ArgCys: 0.671 ± 0.026	4.821ArgAsp: 4.821 ± 0.065	5.192ArgGlu: 5.192 ± 0.071	2.615ArgPhe: 2.615 ± 0.045	6.375ArgGly: 6.375 ± 0.083	2.184ArgHis: 2.184 ± 0.039	3.452ArgIle: 3.452 ± 0.051	1.474ArgLys: 1.474 ± 0.037	9.751ArgLeu: 9.751 ± 0.106	1.863ArgMet: 1.863 ± 0.036	1.365ArgAsn: 1.365 ± 0.029	5.504ArgPro: 5.504 ± 0.072	2.719ArgGln: 2.719 ± 0.045	9.812ArgArg: 9.812 ± 0.11	4.474ArgSer: 4.474 ± 0.063	4.934ArgThr: 4.934 ± 0.056	7.271ArgVal: 7.271 ± 0.078	1.755ArgTrp: 1.755 ± 0.041	2.192ArgTyr: 2.192 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.941SerAla: 5.941 ± 0.057	0.374SerCys: 0.374 ± 0.018	2.893SerAsp: 2.893 ± 0.052	2.56SerGlu: 2.56 ± 0.04	1.583SerPhe: 1.583 ± 0.036	5.225SerGly: 5.225 ± 0.056	0.986SerHis: 0.986 ± 0.027	1.617SerIle: 1.617 ± 0.037	0.881SerLys: 0.881 ± 0.029	4.746SerLeu: 4.746 ± 0.068	1.075SerMet: 1.075 ± 0.026	0.85SerAsn: 0.85 ± 0.026	3.401SerPro: 3.401 ± 0.059	1.222SerGln: 1.222 ± 0.03	4.043SerArg: 4.043 ± 0.058	3.095SerSer: 3.095 ± 0.059	3.322SerThr: 3.322 ± 0.049	4.278SerVal: 4.278 ± 0.056	0.978SerTrp: 0.978 ± 0.033	1.275SerTyr: 1.275 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.956ThrAla: 6.956 ± 0.081	0.463ThrCys: 0.463 ± 0.02	3.186ThrAsp: 3.186 ± 0.051	2.931ThrGlu: 2.931 ± 0.052	1.942ThrPhe: 1.942 ± 0.047	5.587ThrGly: 5.587 ± 0.067	1.196ThrHis: 1.196 ± 0.029	2.207ThrIle: 2.207 ± 0.047	1.193ThrLys: 1.193 ± 0.029	5.833ThrLeu: 5.833 ± 0.07	1.05ThrMet: 1.05 ± 0.031	1.094ThrAsn: 1.094 ± 0.029	4.31ThrPro: 4.31 ± 0.078	1.351ThrGln: 1.351 ± 0.034	4.407ThrArg: 4.407 ± 0.054	3.535ThrSer: 3.535 ± 0.056	4.172ThrThr: 4.172 ± 0.064	5.984ThrVal: 5.984 ± 0.075	1.096ThrTrp: 1.096 ± 0.031	1.441ThrTyr: 1.441 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	12.295ValAla: 12.295 ± 0.111	0.835ValCys: 0.835 ± 0.025	6.196ValAsp: 6.196 ± 0.073	5.951ValGlu: 5.951 ± 0.077	2.528ValPhe: 2.528 ± 0.046	7.849ValGly: 7.849 ± 0.099	1.931ValHis: 1.931 ± 0.04	3.144ValIle: 3.144 ± 0.052	1.441ValLys: 1.441 ± 0.034	10.035ValLeu: 10.035 ± 0.109	1.389ValMet: 1.389 ± 0.032	1.652ValAsn: 1.652 ± 0.037	5.523ValPro: 5.523 ± 0.065	1.934ValGln: 1.934 ± 0.033	8.035ValArg: 8.035 ± 0.092	4.647ValSer: 4.647 ± 0.063	6.01ValThr: 6.01 ± 0.066	10.433ValVal: 10.433 ± 0.124	1.328ValTrp: 1.328 ± 0.033	1.694ValTyr: 1.694 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.624TrpAla: 1.624 ± 0.04	0.162TrpCys: 0.162 ± 0.01	0.863TrpAsp: 0.863 ± 0.024	0.821TrpGlu: 0.821 ± 0.027	0.558TrpPhe: 0.558 ± 0.022	1.084TrpGly: 1.084 ± 0.033	0.369TrpHis: 0.369 ± 0.017	0.624TrpIle: 0.624 ± 0.025	0.346TrpLys: 0.346 ± 0.015	1.975TrpLeu: 1.975 ± 0.046	0.293TrpMet: 0.293 ± 0.014	0.388TrpAsn: 0.388 ± 0.019	0.879TrpPro: 0.879 ± 0.031	0.54TrpGln: 0.54 ± 0.018	1.659TrpArg: 1.659 ± 0.039	1.051TrpSer: 1.051 ± 0.029	1.041TrpThr: 1.041 ± 0.029	1.267TrpVal: 1.267 ± 0.035	0.479TrpTrp: 0.479 ± 0.021	0.409TrpTyr: 0.409 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.793TyrAla: 2.793 ± 0.053	0.187TyrCys: 0.187 ± 0.014	1.723TyrAsp: 1.723 ± 0.035	1.304TyrGlu: 1.304 ± 0.034	0.656TyrPhe: 0.656 ± 0.028	2.046TyrGly: 2.046 ± 0.043	0.468TyrHis: 0.468 ± 0.019	0.601TyrIle: 0.601 ± 0.023	0.344TyrLys: 0.344 ± 0.017	2.452TyrLeu: 2.452 ± 0.045	0.23TyrMet: 0.23 ± 0.016	0.409TyrAsn: 0.409 ± 0.017	1.257TyrPro: 1.257 ± 0.03	0.678TyrGln: 0.678 ± 0.022	1.954TyrArg: 1.954 ± 0.038	0.954TyrSer: 0.954 ± 0.031	1.194TyrThr: 1.194 ± 0.032	2.101TyrVal: 2.101 ± 0.039	0.39TyrTrp: 0.39 ± 0.018	0.571TyrTyr: 0.571 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3739 proteins (1275144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---