Amino acid dipepetide frequency for Tortoise microvirus 81

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.096AlaAla: 7.096 ± 1.94
0.546AlaCys: 0.546 ± 0.464
5.459AlaAsp: 5.459 ± 2.55
6.55AlaGlu: 6.55 ± 1.306
1.638AlaPhe: 1.638 ± 1.013
10.371AlaGly: 10.371 ± 2.818
2.183AlaHis: 2.183 ± 1.281
4.367AlaIle: 4.367 ± 0.944
6.004AlaLys: 6.004 ± 1.294
5.459AlaLeu: 5.459 ± 1.708
2.183AlaMet: 2.183 ± 1.195
2.729AlaAsn: 2.729 ± 1.202
5.459AlaPro: 5.459 ± 2.413
5.459AlaGln: 5.459 ± 1.712
5.459AlaArg: 5.459 ± 0.996
3.275AlaSer: 3.275 ± 1.241
6.004AlaThr: 6.004 ± 1.779
6.55AlaVal: 6.55 ± 2.056
1.092AlaTrp: 1.092 ± 0.67
4.913AlaTyr: 4.913 ± 1.598
0.0AlaXaa: 0.0 ± 0.0
Cys
1.092CysAla: 1.092 ± 1.15
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.546CysGlu: 0.546 ± 0.75
0.0CysPhe: 0.0 ± 0.0
0.546CysGly: 0.546 ± 0.464
0.0CysHis: 0.0 ± 0.0
0.546CysIle: 0.546 ± 0.464
2.183CysLys: 2.183 ± 1.216
1.092CysLeu: 1.092 ± 0.613
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.092CysArg: 1.092 ± 0.927
1.092CysSer: 1.092 ± 0.927
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.546CysTrp: 0.546 ± 0.464
0.546CysTyr: 0.546 ± 0.464
0.0CysXaa: 0.0 ± 0.0
Asp
7.096AspAla: 7.096 ± 1.187
0.546AspCys: 0.546 ± 0.464
3.275AspAsp: 3.275 ± 0.999
0.546AspGlu: 0.546 ± 0.464
3.821AspPhe: 3.821 ± 1.299
2.729AspGly: 2.729 ± 0.882
0.546AspHis: 0.546 ± 0.464
2.729AspIle: 2.729 ± 1.684
1.092AspLys: 1.092 ± 0.927
6.55AspLeu: 6.55 ± 1.87
1.092AspMet: 1.092 ± 0.455
1.092AspAsn: 1.092 ± 0.613
7.096AspPro: 7.096 ± 1.73
2.183AspGln: 2.183 ± 1.199
3.275AspArg: 3.275 ± 0.875
2.729AspSer: 2.729 ± 1.593
2.183AspThr: 2.183 ± 1.139
2.183AspVal: 2.183 ± 0.911
1.092AspTrp: 1.092 ± 0.765
1.092AspTyr: 1.092 ± 0.455
0.0AspXaa: 0.0 ± 0.0
Glu
3.821GluAla: 3.821 ± 1.539
1.092GluCys: 1.092 ± 1.15
6.004GluAsp: 6.004 ± 1.597
3.275GluGlu: 3.275 ± 0.787
3.275GluPhe: 3.275 ± 1.295
2.729GluGly: 2.729 ± 1.277
0.546GluHis: 0.546 ± 0.575
3.275GluIle: 3.275 ± 1.492
4.367GluLys: 4.367 ± 0.944
4.913GluLeu: 4.913 ± 0.757
2.183GluMet: 2.183 ± 1.021
2.729GluAsn: 2.729 ± 1.355
3.275GluPro: 3.275 ± 0.963
1.092GluGln: 1.092 ± 0.542
5.459GluArg: 5.459 ± 1.482
3.275GluSer: 3.275 ± 0.858
3.821GluThr: 3.821 ± 1.331
4.367GluVal: 4.367 ± 1.52
1.638GluTrp: 1.638 ± 1.12
1.092GluTyr: 1.092 ± 0.455
0.0GluXaa: 0.0 ± 0.0
Phe
5.459PheAla: 5.459 ± 1.356
0.546PheCys: 0.546 ± 0.464
1.092PheAsp: 1.092 ± 0.927
3.821PheGlu: 3.821 ± 1.63
2.729PhePhe: 2.729 ± 0.844
3.275PheGly: 3.275 ± 0.999
0.546PheHis: 0.546 ± 0.578
1.638PheIle: 1.638 ± 0.95
1.092PheLys: 1.092 ± 0.635
3.821PheLeu: 3.821 ± 1.254
1.638PheMet: 1.638 ± 0.591
2.183PheAsn: 2.183 ± 1.807
1.638PhePro: 1.638 ± 0.797
1.638PheGln: 1.638 ± 0.95
2.729PheArg: 2.729 ± 1.177
1.092PheSer: 1.092 ± 0.6
0.546PheThr: 0.546 ± 0.385
3.275PheVal: 3.275 ± 1.059
1.092PheTrp: 1.092 ± 0.455
2.729PheTyr: 2.729 ± 1.656
0.0PheXaa: 0.0 ± 0.0
Gly
5.459GlyAla: 5.459 ± 1.352
0.546GlyCys: 0.546 ± 0.464
3.821GlyAsp: 3.821 ± 1.203
5.459GlyGlu: 5.459 ± 1.512
3.275GlyPhe: 3.275 ± 1.539
9.279GlyGly: 9.279 ± 4.095
2.183GlyHis: 2.183 ± 0.979
4.367GlyIle: 4.367 ± 1.207
3.275GlyLys: 3.275 ± 0.873
4.913GlyLeu: 4.913 ± 1.849
2.729GlyMet: 2.729 ± 0.746
1.092GlyAsn: 1.092 ± 0.6
2.729GlyPro: 2.729 ± 1.924
4.367GlyGln: 4.367 ± 1.163
4.913GlyArg: 4.913 ± 1.919
4.913GlySer: 4.913 ± 2.197
6.55GlyThr: 6.55 ± 1.909
6.55GlyVal: 6.55 ± 1.276
1.638GlyTrp: 1.638 ± 0.782
4.367GlyTyr: 4.367 ± 1.543
0.0GlyXaa: 0.0 ± 0.0
His
2.183HisAla: 2.183 ± 0.863
0.546HisCys: 0.546 ± 0.464
1.638HisAsp: 1.638 ± 1.113
3.275HisGlu: 3.275 ± 1.539
1.092HisPhe: 1.092 ± 0.455
0.546HisGly: 0.546 ± 0.464
0.0HisHis: 0.0 ± 0.0
1.092HisIle: 1.092 ± 0.455
0.546HisLys: 0.546 ± 0.385
0.546HisLeu: 0.546 ± 0.75
0.546HisMet: 0.546 ± 0.575
1.092HisAsn: 1.092 ± 0.658
1.092HisPro: 1.092 ± 0.6
1.092HisGln: 1.092 ± 0.658
0.0HisArg: 0.0 ± 0.0
0.546HisSer: 0.546 ± 0.385
1.092HisThr: 1.092 ± 0.996
2.183HisVal: 2.183 ± 1.098
1.092HisTrp: 1.092 ± 0.635
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.821IleAla: 3.821 ± 1.783
0.546IleCys: 0.546 ± 0.464
2.729IleAsp: 2.729 ± 1.4
1.092IleGlu: 1.092 ± 0.693
1.092IlePhe: 1.092 ± 0.77
4.367IleGly: 4.367 ± 1.207
2.183IleHis: 2.183 ± 1.063
2.183IleIle: 2.183 ± 1.083
1.638IleLys: 1.638 ± 1.0
1.638IleLeu: 1.638 ± 0.912
1.092IleMet: 1.092 ± 0.455
2.183IleAsn: 2.183 ± 0.797
2.729IlePro: 2.729 ± 0.786
0.546IleGln: 0.546 ± 0.607
3.821IleArg: 3.821 ± 1.353
3.275IleSer: 3.275 ± 1.69
2.729IleThr: 2.729 ± 1.114
5.459IleVal: 5.459 ± 1.382
1.092IleTrp: 1.092 ± 0.455
0.546IleTyr: 0.546 ± 0.385
0.0IleXaa: 0.0 ± 0.0
Lys
6.55LysAla: 6.55 ± 2.722
0.0LysCys: 0.0 ± 0.0
3.275LysAsp: 3.275 ± 1.152
3.821LysGlu: 3.821 ± 1.522
2.183LysPhe: 2.183 ± 0.513
4.367LysGly: 4.367 ± 0.981
1.092LysHis: 1.092 ± 0.542
1.638LysIle: 1.638 ± 1.154
1.638LysLys: 1.638 ± 0.67
2.183LysLeu: 2.183 ± 1.039
1.638LysMet: 1.638 ± 0.943
1.092LysAsn: 1.092 ± 0.542
3.821LysPro: 3.821 ± 1.205
2.183LysGln: 2.183 ± 1.098
3.275LysArg: 3.275 ± 1.734
2.183LysSer: 2.183 ± 1.139
2.729LysThr: 2.729 ± 1.969
1.638LysVal: 1.638 ± 0.592
0.546LysTrp: 0.546 ± 0.578
2.183LysTyr: 2.183 ± 1.271
0.0LysXaa: 0.0 ± 0.0
Leu
6.004LeuAla: 6.004 ± 1.286
0.0LeuCys: 0.0 ± 0.0
3.275LeuAsp: 3.275 ± 1.799
2.729LeuGlu: 2.729 ± 0.883
2.183LeuPhe: 2.183 ± 1.2
7.096LeuGly: 7.096 ± 1.715
1.092LeuHis: 1.092 ± 0.455
1.092LeuIle: 1.092 ± 0.879
1.638LeuLys: 1.638 ± 0.854
4.367LeuLeu: 4.367 ± 1.564
1.638LeuMet: 1.638 ± 0.768
6.004LeuAsn: 6.004 ± 2.156
5.459LeuPro: 5.459 ± 1.464
3.821LeuGln: 3.821 ± 2.066
7.642LeuArg: 7.642 ± 1.968
4.913LeuSer: 4.913 ± 1.306
8.188LeuThr: 8.188 ± 0.935
3.821LeuVal: 3.821 ± 1.096
0.546LeuTrp: 0.546 ± 0.385
1.092LeuTyr: 1.092 ± 1.045
0.0LeuXaa: 0.0 ± 0.0
Met
5.459MetAla: 5.459 ± 1.356
0.546MetCys: 0.546 ± 0.464
1.638MetAsp: 1.638 ± 0.704
2.183MetGlu: 2.183 ± 0.93
0.546MetPhe: 0.546 ± 0.385
1.638MetGly: 1.638 ± 0.812
0.546MetHis: 0.546 ± 0.578
0.546MetIle: 0.546 ± 0.385
2.183MetLys: 2.183 ± 1.958
2.729MetLeu: 2.729 ± 1.39
0.0MetMet: 0.0 ± 0.0
0.546MetAsn: 0.546 ± 0.464
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.183MetArg: 2.183 ± 0.747
0.0MetSer: 0.0 ± 0.0
1.092MetThr: 1.092 ± 0.78
0.546MetVal: 0.546 ± 0.464
1.092MetTrp: 1.092 ± 0.957
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.275AsnAla: 3.275 ± 1.449
0.0AsnCys: 0.0 ± 0.0
0.546AsnAsp: 0.546 ± 0.464
3.275AsnGlu: 3.275 ± 0.904
2.183AsnPhe: 2.183 ± 1.128
4.367AsnGly: 4.367 ± 1.336
0.0AsnHis: 0.0 ± 0.0
1.092AsnIle: 1.092 ± 0.6
1.638AsnLys: 1.638 ± 0.797
2.729AsnLeu: 2.729 ± 1.715
0.546AsnMet: 0.546 ± 0.834
2.729AsnAsn: 2.729 ± 1.427
2.183AsnPro: 2.183 ± 0.611
1.638AsnGln: 1.638 ± 0.592
4.913AsnArg: 4.913 ± 1.163
3.275AsnSer: 3.275 ± 1.717
1.638AsnThr: 1.638 ± 0.824
3.275AsnVal: 3.275 ± 0.885
1.092AsnTrp: 1.092 ± 0.6
1.092AsnTyr: 1.092 ± 0.78
0.0AsnXaa: 0.0 ± 0.0
Pro
8.188ProAla: 8.188 ± 2.678
0.0ProCys: 0.0 ± 0.0
2.729ProAsp: 2.729 ± 0.985
5.459ProGlu: 5.459 ± 0.783
3.821ProPhe: 3.821 ± 1.537
2.183ProGly: 2.183 ± 1.53
1.638ProHis: 1.638 ± 0.952
1.638ProIle: 1.638 ± 0.704
1.638ProLys: 1.638 ± 0.812
6.004ProLeu: 6.004 ± 1.495
1.092ProMet: 1.092 ± 1.213
1.638ProAsn: 1.638 ± 0.95
5.459ProPro: 5.459 ± 2.086
2.729ProGln: 2.729 ± 0.838
6.004ProArg: 6.004 ± 1.878
3.275ProSer: 3.275 ± 1.375
2.183ProThr: 2.183 ± 0.797
3.821ProVal: 3.821 ± 1.087
1.092ProTrp: 1.092 ± 0.613
0.546ProTyr: 0.546 ± 0.464
0.0ProXaa: 0.0 ± 0.0
Gln
2.729GlnAla: 2.729 ± 1.07
0.546GlnCys: 0.546 ± 0.464
2.729GlnAsp: 2.729 ± 0.648
1.638GlnGlu: 1.638 ± 1.03
1.092GlnPhe: 1.092 ± 0.6
2.183GlnGly: 2.183 ± 0.794
0.0GlnHis: 0.0 ± 0.0
1.638GlnIle: 1.638 ± 0.592
2.729GlnLys: 2.729 ± 1.349
1.638GlnLeu: 1.638 ± 0.67
2.183GlnMet: 2.183 ± 0.96
1.638GlnAsn: 1.638 ± 1.218
3.821GlnPro: 3.821 ± 1.139
1.092GlnGln: 1.092 ± 1.213
3.821GlnArg: 3.821 ± 1.654
1.638GlnSer: 1.638 ± 0.767
1.092GlnThr: 1.092 ± 0.613
3.275GlnVal: 3.275 ± 1.039
0.546GlnTrp: 0.546 ± 0.464
0.546GlnTyr: 0.546 ± 0.464
0.0GlnXaa: 0.0 ± 0.0
Arg
8.188ArgAla: 8.188 ± 1.794
1.092ArgCys: 1.092 ± 0.455
4.367ArgAsp: 4.367 ± 1.755
3.275ArgGlu: 3.275 ± 1.359
3.821ArgPhe: 3.821 ± 1.11
3.821ArgGly: 3.821 ± 1.547
3.275ArgHis: 3.275 ± 1.408
5.459ArgIle: 5.459 ± 1.182
4.913ArgLys: 4.913 ± 1.656
3.821ArgLeu: 3.821 ± 1.062
0.546ArgMet: 0.546 ± 0.712
5.459ArgAsn: 5.459 ± 1.57
2.729ArgPro: 2.729 ± 1.265
3.821ArgGln: 3.821 ± 1.298
8.188ArgArg: 8.188 ± 2.523
3.275ArgSer: 3.275 ± 1.87
6.55ArgThr: 6.55 ± 3.008
3.821ArgVal: 3.821 ± 1.089
0.0ArgTrp: 0.0 ± 0.0
2.729ArgTyr: 2.729 ± 1.87
0.0ArgXaa: 0.0 ± 0.0
Ser
3.275SerAla: 3.275 ± 1.059
1.092SerCys: 1.092 ± 0.846
2.729SerAsp: 2.729 ± 1.472
2.729SerGlu: 2.729 ± 0.816
3.275SerPhe: 3.275 ± 1.286
6.004SerGly: 6.004 ± 3.49
0.546SerHis: 0.546 ± 0.578
2.729SerIle: 2.729 ± 0.768
2.183SerLys: 2.183 ± 1.311
5.459SerLeu: 5.459 ± 1.381
1.092SerMet: 1.092 ± 0.75
1.638SerAsn: 1.638 ± 0.797
2.183SerPro: 2.183 ± 1.298
0.546SerGln: 0.546 ± 0.464
3.275SerArg: 3.275 ± 1.194
3.275SerSer: 3.275 ± 1.489
3.821SerThr: 3.821 ± 1.637
3.275SerVal: 3.275 ± 0.993
0.546SerTrp: 0.546 ± 0.385
2.729SerTyr: 2.729 ± 1.814
0.0SerXaa: 0.0 ± 0.0
Thr
4.367ThrAla: 4.367 ± 1.354
0.546ThrCys: 0.546 ± 0.75
2.729ThrAsp: 2.729 ± 0.958
3.821ThrGlu: 3.821 ± 1.096
1.638ThrPhe: 1.638 ± 1.189
8.188ThrGly: 8.188 ± 2.332
1.638ThrHis: 1.638 ± 1.02
4.367ThrIle: 4.367 ± 1.349
2.729ThrLys: 2.729 ± 1.231
6.004ThrLeu: 6.004 ± 1.884
0.0ThrMet: 0.0 ± 0.0
0.546ThrAsn: 0.546 ± 0.498
2.729ThrPro: 2.729 ± 0.884
1.638ThrGln: 1.638 ± 1.253
3.275ThrArg: 3.275 ± 1.822
1.638ThrSer: 1.638 ± 0.712
8.188ThrThr: 8.188 ± 2.193
4.367ThrVal: 4.367 ± 1.51
0.546ThrTrp: 0.546 ± 0.575
3.821ThrTyr: 3.821 ± 1.981
0.0ThrXaa: 0.0 ± 0.0
Val
5.459ValAla: 5.459 ± 2.97
0.546ValCys: 0.546 ± 0.607
2.729ValAsp: 2.729 ± 1.198
7.096ValGlu: 7.096 ± 1.152
3.275ValPhe: 3.275 ± 1.419
4.367ValGly: 4.367 ± 2.002
1.092ValHis: 1.092 ± 0.744
2.183ValIle: 2.183 ± 1.105
3.275ValLys: 3.275 ± 0.769
4.913ValLeu: 4.913 ± 1.557
0.546ValMet: 0.546 ± 0.385
2.183ValAsn: 2.183 ± 1.236
7.096ValPro: 7.096 ± 1.671
2.729ValGln: 2.729 ± 1.897
7.096ValArg: 7.096 ± 1.572
3.275ValSer: 3.275 ± 1.459
3.275ValThr: 3.275 ± 1.408
6.004ValVal: 6.004 ± 1.779
0.0ValTrp: 0.0 ± 0.0
0.546ValTyr: 0.546 ± 0.464
0.0ValXaa: 0.0 ± 0.0
Trp
0.546TrpAla: 0.546 ± 0.575
0.546TrpCys: 0.546 ± 0.607
0.546TrpAsp: 0.546 ± 0.575
1.092TrpGlu: 1.092 ± 0.635
0.0TrpPhe: 0.0 ± 0.0
2.183TrpGly: 2.183 ± 1.295
0.546TrpHis: 0.546 ± 0.464
0.546TrpIle: 0.546 ± 0.464
1.638TrpLys: 1.638 ± 0.592
1.092TrpLeu: 1.092 ± 0.927
0.546TrpMet: 0.546 ± 0.477
1.638TrpAsn: 1.638 ± 1.013
0.546TrpPro: 0.546 ± 0.464
0.546TrpGln: 0.546 ± 0.464
1.092TrpArg: 1.092 ± 0.635
1.638TrpSer: 1.638 ± 0.967
0.546TrpThr: 0.546 ± 0.385
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.546TrpTyr: 0.546 ± 0.578
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.729TyrAla: 2.729 ± 1.122
0.0TyrCys: 0.0 ± 0.0
1.638TyrAsp: 1.638 ± 0.782
0.546TyrGlu: 0.546 ± 0.834
1.638TyrPhe: 1.638 ± 0.95
2.183TyrGly: 2.183 ± 1.182
0.546TyrHis: 0.546 ± 0.498
1.638TyrIle: 1.638 ± 0.95
1.638TyrLys: 1.638 ± 0.5
2.729TyrLeu: 2.729 ± 1.557
1.638TyrMet: 1.638 ± 0.835
3.275TyrAsn: 3.275 ± 0.969
1.092TyrPro: 1.092 ± 0.724
0.0TyrGln: 0.0 ± 0.0
1.638TyrArg: 1.638 ± 1.12
3.821TyrSer: 3.821 ± 1.654
0.546TyrThr: 0.546 ± 0.464
3.275TyrVal: 3.275 ± 0.824
0.546TyrTrp: 0.546 ± 0.464
0.546TyrTyr: 0.546 ± 0.578
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1833 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski