Amino acid dipepetide frequency for Apis mellifera associated microvirus 60

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.417AlaAla: 10.417 ± 4.915
0.744AlaCys: 0.744 ± 0.676
5.952AlaAsp: 5.952 ± 2.029
2.232AlaGlu: 2.232 ± 0.827
1.488AlaPhe: 1.488 ± 1.001
4.464AlaGly: 4.464 ± 2.421
0.744AlaHis: 0.744 ± 0.986
2.232AlaIle: 2.232 ± 0.963
3.72AlaLys: 3.72 ± 2.752
9.673AlaLeu: 9.673 ± 1.43
0.744AlaMet: 0.744 ± 0.942
2.232AlaAsn: 2.232 ± 1.063
1.488AlaPro: 1.488 ± 0.81
5.208AlaGln: 5.208 ± 2.494
2.232AlaArg: 2.232 ± 1.502
5.208AlaSer: 5.208 ± 2.981
6.696AlaThr: 6.696 ± 1.892
2.976AlaVal: 2.976 ± 1.304
1.488AlaTrp: 1.488 ± 1.014
3.72AlaTyr: 3.72 ± 1.268
0.0AlaXaa: 0.0 ± 0.0
Cys
0.744CysAla: 0.744 ± 0.676
0.0CysCys: 0.0 ± 0.0
1.488CysAsp: 1.488 ± 1.084
0.744CysGlu: 0.744 ± 0.676
0.0CysPhe: 0.0 ± 0.0
2.232CysGly: 2.232 ± 1.234
0.0CysHis: 0.0 ± 0.0
0.744CysIle: 0.744 ± 0.676
0.744CysLys: 0.744 ± 1.055
0.744CysLeu: 0.744 ± 0.501
0.0CysMet: 0.0 ± 0.0
0.744CysAsn: 0.744 ± 0.866
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.488CysArg: 1.488 ± 1.001
0.744CysSer: 0.744 ± 0.676
0.744CysThr: 0.744 ± 0.676
0.744CysVal: 0.744 ± 0.676
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.72AspAla: 3.72 ± 2.615
0.0AspCys: 0.0 ± 0.0
2.976AspAsp: 2.976 ± 1.194
2.232AspGlu: 2.232 ± 1.107
4.464AspPhe: 4.464 ± 1.91
3.72AspGly: 3.72 ± 1.268
0.744AspHis: 0.744 ± 0.501
1.488AspIle: 1.488 ± 0.959
2.976AspLys: 2.976 ± 1.787
5.952AspLeu: 5.952 ± 2.264
0.744AspMet: 0.744 ± 0.986
2.976AspAsn: 2.976 ± 1.37
0.744AspPro: 0.744 ± 0.501
0.744AspGln: 0.744 ± 1.055
2.232AspArg: 2.232 ± 1.185
2.976AspSer: 2.976 ± 1.024
3.72AspThr: 3.72 ± 1.182
2.976AspVal: 2.976 ± 0.859
0.744AspTrp: 0.744 ± 0.501
5.208AspTyr: 5.208 ± 1.392
0.0AspXaa: 0.0 ± 0.0
Glu
5.208GluAla: 5.208 ± 1.704
1.488GluCys: 1.488 ± 1.352
0.744GluAsp: 0.744 ± 1.055
6.696GluGlu: 6.696 ± 3.58
0.744GluPhe: 0.744 ± 0.676
2.976GluGly: 2.976 ± 2.028
3.72GluHis: 3.72 ± 1.858
4.464GluIle: 4.464 ± 1.374
5.208GluLys: 5.208 ± 2.226
5.208GluLeu: 5.208 ± 1.156
2.232GluMet: 2.232 ± 1.238
2.976GluAsn: 2.976 ± 2.013
4.464GluPro: 4.464 ± 2.679
3.72GluGln: 3.72 ± 1.182
2.976GluArg: 2.976 ± 1.8
5.208GluSer: 5.208 ± 1.695
2.976GluThr: 2.976 ± 1.058
2.976GluVal: 2.976 ± 1.591
0.744GluTrp: 0.744 ± 1.055
2.232GluTyr: 2.232 ± 0.827
0.0GluXaa: 0.0 ± 0.0
Phe
1.488PheAla: 1.488 ± 0.655
0.744PheCys: 0.744 ± 0.501
1.488PheAsp: 1.488 ± 2.111
0.744PheGlu: 0.744 ± 0.942
0.744PhePhe: 0.744 ± 0.501
5.208PheGly: 5.208 ± 2.304
0.0PheHis: 0.0 ± 0.0
2.976PheIle: 2.976 ± 1.879
2.232PheLys: 2.232 ± 1.234
3.72PheLeu: 3.72 ± 1.388
0.0PheMet: 0.0 ± 0.0
2.232PheAsn: 2.232 ± 0.95
0.0PhePro: 0.0 ± 0.0
1.488PheGln: 1.488 ± 0.81
5.208PheArg: 5.208 ± 1.674
1.488PheSer: 1.488 ± 1.001
2.976PheThr: 2.976 ± 1.37
0.744PheVal: 0.744 ± 0.501
0.744PheTrp: 0.744 ± 0.501
1.488PheTyr: 1.488 ± 0.848
0.0PheXaa: 0.0 ± 0.0
Gly
7.44GlyAla: 7.44 ± 2.061
1.488GlyCys: 1.488 ± 0.655
4.464GlyAsp: 4.464 ± 0.805
2.232GlyGlu: 2.232 ± 1.045
2.232GlyPhe: 2.232 ± 1.234
6.696GlyGly: 6.696 ± 1.515
0.0GlyHis: 0.0 ± 0.0
5.208GlyIle: 5.208 ± 1.433
6.696GlyLys: 6.696 ± 3.501
6.696GlyLeu: 6.696 ± 1.882
0.744GlyMet: 0.744 ± 0.501
2.232GlyAsn: 2.232 ± 0.72
2.976GlyPro: 2.976 ± 1.621
3.72GlyGln: 3.72 ± 1.395
0.744GlyArg: 0.744 ± 0.676
2.976GlySer: 2.976 ± 2.606
7.44GlyThr: 7.44 ± 3.398
3.72GlyVal: 3.72 ± 1.388
0.0GlyTrp: 0.0 ± 0.0
3.72GlyTyr: 3.72 ± 1.955
0.0GlyXaa: 0.0 ± 0.0
His
1.488HisAla: 1.488 ± 1.373
0.0HisCys: 0.0 ± 0.0
0.744HisAsp: 0.744 ± 0.676
2.976HisGlu: 2.976 ± 2.169
1.488HisPhe: 1.488 ± 0.655
1.488HisGly: 1.488 ± 1.001
0.0HisHis: 0.0 ± 0.0
0.744HisIle: 0.744 ± 0.501
0.744HisLys: 0.744 ± 0.676
2.232HisLeu: 2.232 ± 1.045
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.744HisPro: 0.744 ± 0.866
0.744HisGln: 0.744 ± 0.501
0.744HisArg: 0.744 ± 0.986
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.232HisVal: 2.232 ± 1.045
0.0HisTrp: 0.0 ± 0.0
2.232HisTyr: 2.232 ± 1.515
0.0HisXaa: 0.0 ± 0.0
Ile
3.72IleAla: 3.72 ± 2.454
0.744IleCys: 0.744 ± 0.501
2.232IleAsp: 2.232 ± 0.963
2.232IleGlu: 2.232 ± 0.72
2.232IlePhe: 2.232 ± 0.827
2.976IleGly: 2.976 ± 1.37
0.744IleHis: 0.744 ± 0.501
1.488IleIle: 1.488 ± 0.848
4.464IleLys: 4.464 ± 1.523
5.208IleLeu: 5.208 ± 1.704
2.976IleMet: 2.976 ± 1.055
2.976IleAsn: 2.976 ± 1.304
2.976IlePro: 2.976 ± 1.426
3.72IleGln: 3.72 ± 1.093
1.488IleArg: 1.488 ± 0.655
3.72IleSer: 3.72 ± 1.724
3.72IleThr: 3.72 ± 0.844
2.232IleVal: 2.232 ± 1.368
1.488IleTrp: 1.488 ± 1.001
3.72IleTyr: 3.72 ± 1.553
0.0IleXaa: 0.0 ± 0.0
Lys
1.488LysAla: 1.488 ± 1.014
0.744LysCys: 0.744 ± 0.676
6.696LysAsp: 6.696 ± 2.589
3.72LysGlu: 3.72 ± 2.546
2.232LysPhe: 2.232 ± 0.95
5.208LysGly: 5.208 ± 1.24
1.488LysHis: 1.488 ± 1.352
0.744LysIle: 0.744 ± 1.055
11.905LysLys: 11.905 ± 7.381
2.976LysLeu: 2.976 ± 1.476
1.488LysMet: 1.488 ± 0.81
4.464LysAsn: 4.464 ± 2.463
4.464LysPro: 4.464 ± 1.404
5.208LysGln: 5.208 ± 3.343
7.44LysArg: 7.44 ± 3.058
3.72LysSer: 3.72 ± 1.182
5.952LysThr: 5.952 ± 2.768
1.488LysVal: 1.488 ± 1.378
0.0LysTrp: 0.0 ± 0.0
2.976LysTyr: 2.976 ± 1.787
0.0LysXaa: 0.0 ± 0.0
Leu
4.464LeuAla: 4.464 ± 1.792
0.0LeuCys: 0.0 ± 0.0
2.976LeuAsp: 2.976 ± 1.539
6.696LeuGlu: 6.696 ± 1.895
1.488LeuPhe: 1.488 ± 1.352
2.976LeuGly: 2.976 ± 1.621
0.744LeuHis: 0.744 ± 1.055
4.464LeuIle: 4.464 ± 1.811
11.161LeuLys: 11.161 ± 4.935
5.952LeuLeu: 5.952 ± 2.322
2.232LeuMet: 2.232 ± 1.419
5.952LeuAsn: 5.952 ± 2.462
8.185LeuPro: 8.185 ± 2.999
2.976LeuGln: 2.976 ± 1.158
2.232LeuArg: 2.232 ± 1.045
4.464LeuSer: 4.464 ± 0.846
5.208LeuThr: 5.208 ± 1.885
6.696LeuVal: 6.696 ± 2.824
0.744LeuTrp: 0.744 ± 0.676
5.208LeuTyr: 5.208 ± 2.103
0.0LeuXaa: 0.0 ± 0.0
Met
2.976MetAla: 2.976 ± 1.621
1.488MetCys: 1.488 ± 1.084
2.232MetAsp: 2.232 ± 0.963
1.488MetGlu: 1.488 ± 1.283
1.488MetPhe: 1.488 ± 1.001
0.744MetGly: 0.744 ± 0.501
0.0MetHis: 0.0 ± 0.0
2.232MetIle: 2.232 ± 1.063
1.488MetLys: 1.488 ± 0.81
2.232MetLeu: 2.232 ± 1.257
0.0MetMet: 0.0 ± 0.587
0.0MetAsn: 0.0 ± 0.0
1.488MetPro: 1.488 ± 0.968
1.488MetGln: 1.488 ± 1.014
0.0MetArg: 0.0 ± 0.0
2.232MetSer: 2.232 ± 0.72
2.232MetThr: 2.232 ± 1.502
0.744MetVal: 0.744 ± 1.055
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.232AsnAla: 2.232 ± 0.963
1.488AsnCys: 1.488 ± 0.998
0.744AsnAsp: 0.744 ± 0.501
2.976AsnGlu: 2.976 ± 2.132
0.0AsnPhe: 0.0 ± 0.0
2.232AsnGly: 2.232 ± 0.95
0.0AsnHis: 0.0 ± 0.0
5.952AsnIle: 5.952 ± 2.516
2.232AsnLys: 2.232 ± 1.684
2.232AsnLeu: 2.232 ± 0.72
0.744AsnMet: 0.744 ± 0.501
0.744AsnAsn: 0.744 ± 0.501
5.952AsnPro: 5.952 ± 1.54
1.488AsnGln: 1.488 ± 0.81
2.232AsnArg: 2.232 ± 0.963
4.464AsnSer: 4.464 ± 1.413
2.232AsnThr: 2.232 ± 0.963
3.72AsnVal: 3.72 ± 1.001
0.744AsnTrp: 0.744 ± 0.501
0.744AsnTyr: 0.744 ± 0.501
0.0AsnXaa: 0.0 ± 0.0
Pro
3.72ProAla: 3.72 ± 2.104
0.744ProCys: 0.744 ± 0.676
2.232ProAsp: 2.232 ± 0.963
5.952ProGlu: 5.952 ± 2.616
1.488ProPhe: 1.488 ± 0.959
4.464ProGly: 4.464 ± 1.215
0.744ProHis: 0.744 ± 0.676
5.952ProIle: 5.952 ± 1.852
4.464ProLys: 4.464 ± 1.242
3.72ProLeu: 3.72 ± 1.268
2.232ProMet: 2.232 ± 0.925
0.744ProAsn: 0.744 ± 0.501
0.0ProPro: 0.0 ± 0.0
2.976ProGln: 2.976 ± 1.426
1.488ProArg: 1.488 ± 1.001
3.72ProSer: 3.72 ± 1.317
2.976ProThr: 2.976 ± 1.158
2.232ProVal: 2.232 ± 1.238
0.744ProTrp: 0.744 ± 0.501
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.464GlnAla: 4.464 ± 2.431
0.0GlnCys: 0.0 ± 0.0
2.232GlnAsp: 2.232 ± 1.234
5.208GlnGlu: 5.208 ± 2.801
3.72GlnPhe: 3.72 ± 1.834
6.696GlnGly: 6.696 ± 3.057
1.488GlnHis: 1.488 ± 1.532
3.72GlnIle: 3.72 ± 1.376
3.72GlnLys: 3.72 ± 1.182
1.488GlnLeu: 1.488 ± 1.084
0.0GlnMet: 0.0 ± 0.0
2.976GlnAsn: 2.976 ± 0.714
0.0GlnPro: 0.0 ± 0.0
8.185GlnGln: 8.185 ± 3.292
2.232GlnArg: 2.232 ± 0.963
2.976GlnSer: 2.976 ± 3.0
3.72GlnThr: 3.72 ± 1.829
2.976GlnVal: 2.976 ± 0.859
0.744GlnTrp: 0.744 ± 0.676
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.976ArgAla: 2.976 ± 1.024
0.0ArgCys: 0.0 ± 0.0
2.976ArgAsp: 2.976 ± 1.936
4.464ArgGlu: 4.464 ± 2.664
1.488ArgPhe: 1.488 ± 1.001
2.976ArgGly: 2.976 ± 1.37
0.744ArgHis: 0.744 ± 1.055
2.232ArgIle: 2.232 ± 1.889
2.232ArgLys: 2.232 ± 1.234
4.464ArgLeu: 4.464 ± 1.71
4.464ArgMet: 4.464 ± 0.813
2.232ArgAsn: 2.232 ± 0.95
3.72ArgPro: 3.72 ± 1.388
2.232ArgGln: 2.232 ± 0.72
3.72ArgArg: 3.72 ± 1.003
3.72ArgSer: 3.72 ± 1.831
2.232ArgThr: 2.232 ± 1.257
2.232ArgVal: 2.232 ± 0.95
0.0ArgTrp: 0.0 ± 0.0
2.232ArgTyr: 2.232 ± 1.502
0.0ArgXaa: 0.0 ± 0.0
Ser
5.208SerAla: 5.208 ± 2.55
0.744SerCys: 0.744 ± 0.501
2.232SerAsp: 2.232 ± 0.72
5.952SerGlu: 5.952 ± 1.39
1.488SerPhe: 1.488 ± 1.001
3.72SerGly: 3.72 ± 2.02
2.976SerHis: 2.976 ± 1.8
6.696SerIle: 6.696 ± 1.404
2.232SerLys: 2.232 ± 1.34
3.72SerLeu: 3.72 ± 1.703
2.232SerMet: 2.232 ± 1.063
3.72SerAsn: 3.72 ± 1.708
2.976SerPro: 2.976 ± 0.935
2.232SerGln: 2.232 ± 0.963
2.976SerArg: 2.976 ± 1.304
2.976SerSer: 2.976 ± 2.005
6.696SerThr: 6.696 ± 2.371
2.976SerVal: 2.976 ± 0.714
0.0SerTrp: 0.0 ± 0.0
1.488SerTyr: 1.488 ± 0.959
0.0SerXaa: 0.0 ± 0.0
Thr
7.44ThrAla: 7.44 ± 2.497
0.0ThrCys: 0.0 ± 0.0
2.976ThrAsp: 2.976 ± 1.251
4.464ThrGlu: 4.464 ± 2.002
3.72ThrPhe: 3.72 ± 1.252
5.208ThrGly: 5.208 ± 1.198
0.744ThrHis: 0.744 ± 0.501
2.232ThrIle: 2.232 ± 1.502
4.464ThrLys: 4.464 ± 1.69
6.696ThrLeu: 6.696 ± 1.736
1.488ThrMet: 1.488 ± 0.81
2.976ThrAsn: 2.976 ± 1.37
5.208ThrPro: 5.208 ± 1.433
1.488ThrGln: 1.488 ± 1.973
5.952ThrArg: 5.952 ± 2.74
5.952ThrSer: 5.952 ± 2.147
5.208ThrThr: 5.208 ± 3.31
2.232ThrVal: 2.232 ± 1.184
0.0ThrTrp: 0.0 ± 0.0
1.488ThrTyr: 1.488 ± 0.655
0.0ThrXaa: 0.0 ± 0.0
Val
1.488ValAla: 1.488 ± 1.001
0.744ValCys: 0.744 ± 1.055
0.744ValAsp: 0.744 ± 0.676
2.232ValGlu: 2.232 ± 1.063
2.232ValPhe: 2.232 ± 1.234
2.976ValGly: 2.976 ± 1.362
0.0ValHis: 0.0 ± 0.0
1.488ValIle: 1.488 ± 1.251
2.976ValLys: 2.976 ± 2.08
6.696ValLeu: 6.696 ± 1.615
1.488ValMet: 1.488 ± 1.263
2.232ValAsn: 2.232 ± 1.258
4.464ValPro: 4.464 ± 2.41
5.208ValGln: 5.208 ± 0.976
4.464ValArg: 4.464 ± 1.476
3.72ValSer: 3.72 ± 1.305
1.488ValThr: 1.488 ± 0.655
2.976ValVal: 2.976 ± 1.327
0.744ValTrp: 0.744 ± 0.501
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.744TrpAla: 0.744 ± 0.676
0.0TrpCys: 0.0 ± 0.0
1.488TrpAsp: 1.488 ± 0.959
1.488TrpGlu: 1.488 ± 0.655
1.488TrpPhe: 1.488 ± 1.001
1.488TrpGly: 1.488 ± 1.014
0.744TrpHis: 0.744 ± 0.501
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.744TrpAsn: 0.744 ± 0.501
0.744TrpPro: 0.744 ± 0.501
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.232TyrAla: 2.232 ± 0.928
0.744TyrCys: 0.744 ± 0.676
3.72TyrAsp: 3.72 ± 2.003
2.232TyrGlu: 2.232 ± 0.95
1.488TyrPhe: 1.488 ± 1.001
2.976TyrGly: 2.976 ± 1.15
2.976TyrHis: 2.976 ± 1.304
0.0TyrIle: 0.0 ± 0.0
0.744TyrLys: 0.744 ± 0.986
5.208TyrLeu: 5.208 ± 2.874
0.744TyrMet: 0.744 ± 0.676
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
3.72TyrGln: 3.72 ± 1.553
1.488TyrArg: 1.488 ± 1.001
2.976TyrSer: 2.976 ± 0.714
3.72TyrThr: 3.72 ± 1.317
1.488TyrVal: 1.488 ± 0.655
0.0TyrTrp: 0.0 ± 0.0
2.976TyrTyr: 2.976 ± 1.672
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1345 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski