Amino acid dipepetide frequency for Hubei tombus-like virus 34

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.635AlaAla: 21.635 ± 2.512
2.404AlaCys: 2.404 ± 1.475
4.808AlaAsp: 4.808 ± 0.553
4.207AlaGlu: 4.207 ± 1.196
4.207AlaPhe: 4.207 ± 1.032
6.611AlaGly: 6.611 ± 1.394
3.005AlaHis: 3.005 ± 1.127
5.409AlaIle: 5.409 ± 1.653
1.202AlaLys: 1.202 ± 0.738
13.221AlaLeu: 13.221 ± 0.522
4.808AlaMet: 4.808 ± 2.325
3.606AlaAsn: 3.606 ± 1.115
8.413AlaPro: 8.413 ± 0.77
1.803AlaGln: 1.803 ± 0.558
8.413AlaArg: 8.413 ± 1.527
8.413AlaSer: 8.413 ± 0.564
8.413AlaThr: 8.413 ± 0.561
12.62AlaVal: 12.62 ± 2.626
1.202AlaTrp: 1.202 ± 0.731
3.606AlaTyr: 3.606 ± 0.823
0.0AlaXaa: 0.0 ± 0.0
Cys
1.202CysAla: 1.202 ± 0.587
0.0CysCys: 0.0 ± 0.0
0.601CysAsp: 0.601 ± 0.369
1.202CysGlu: 1.202 ± 1.42
0.0CysPhe: 0.0 ± 0.0
0.601CysGly: 0.601 ± 0.71
1.803CysHis: 1.803 ± 0.676
1.202CysIle: 1.202 ± 0.587
1.202CysLys: 1.202 ± 0.587
0.601CysLeu: 0.601 ± 0.369
0.0CysMet: 0.0 ± 0.0
1.202CysAsn: 1.202 ± 0.738
1.202CysPro: 1.202 ± 0.329
1.202CysGln: 1.202 ± 0.738
0.601CysArg: 0.601 ± 0.369
0.0CysSer: 0.0 ± 0.0
1.202CysThr: 1.202 ± 0.329
0.601CysVal: 0.601 ± 0.369
0.0CysTrp: 0.0 ± 0.0
0.601CysTyr: 0.601 ± 0.71
0.0CysXaa: 0.0 ± 0.0
Asp
6.01AspAla: 6.01 ± 1.625
1.202AspCys: 1.202 ± 0.587
1.803AspAsp: 1.803 ± 1.25
0.601AspGlu: 0.601 ± 0.71
1.803AspPhe: 1.803 ± 0.558
4.207AspGly: 4.207 ± 0.944
2.404AspHis: 2.404 ± 1.113
1.202AspIle: 1.202 ± 0.587
0.0AspLys: 0.0 ± 0.0
4.207AspLeu: 4.207 ± 1.032
1.202AspMet: 1.202 ± 0.329
1.803AspAsn: 1.803 ± 0.66
3.005AspPro: 3.005 ± 1.127
2.404AspGln: 2.404 ± 0.658
5.409AspArg: 5.409 ± 3.319
2.404AspSer: 2.404 ± 0.591
1.803AspThr: 1.803 ± 0.558
3.606AspVal: 3.606 ± 0.857
0.601AspTrp: 0.601 ± 0.71
3.005AspTyr: 3.005 ± 0.922
0.0AspXaa: 0.0 ± 0.0
Glu
3.606GluAla: 3.606 ± 0.156
1.202GluCys: 1.202 ± 1.42
3.005GluAsp: 3.005 ± 1.238
0.0GluGlu: 0.0 ± 0.0
1.803GluPhe: 1.803 ± 0.66
1.202GluGly: 1.202 ± 0.329
1.803GluHis: 1.803 ± 0.411
0.601GluIle: 0.601 ± 0.71
4.808GluLys: 4.808 ± 1.443
0.601GluLeu: 0.601 ± 0.369
1.202GluMet: 1.202 ± 0.738
1.803GluAsn: 1.803 ± 0.558
3.005GluPro: 3.005 ± 0.922
1.202GluGln: 1.202 ± 0.738
4.207GluArg: 4.207 ± 0.596
2.404GluSer: 2.404 ± 1.475
2.404GluThr: 2.404 ± 1.058
3.606GluVal: 3.606 ± 1.558
1.202GluTrp: 1.202 ± 0.329
1.803GluTyr: 1.803 ± 0.676
0.0GluXaa: 0.0 ± 0.0
Phe
5.409PheAla: 5.409 ± 1.162
0.0PheCys: 0.0 ± 0.0
2.404PheAsp: 2.404 ± 0.591
2.404PheGlu: 2.404 ± 1.175
4.808PhePhe: 4.808 ± 2.496
1.202PheGly: 1.202 ± 0.738
1.803PheHis: 1.803 ± 0.411
1.202PheIle: 1.202 ± 0.329
0.601PheLys: 0.601 ± 0.369
1.202PheLeu: 1.202 ± 0.329
0.601PheMet: 0.601 ± 0.422
1.202PheAsn: 1.202 ± 0.843
1.803PhePro: 1.803 ± 0.66
1.202PheGln: 1.202 ± 0.329
2.404PheArg: 2.404 ± 1.462
3.005PheSer: 3.005 ± 0.225
3.005PheThr: 3.005 ± 1.469
3.606PheVal: 3.606 ± 1.353
0.0PheTrp: 0.0 ± 0.0
0.601PheTyr: 0.601 ± 0.369
0.0PheXaa: 0.0 ± 0.0
Gly
9.014GlyAla: 9.014 ± 1.579
0.601GlyCys: 0.601 ± 0.71
2.404GlyAsp: 2.404 ± 1.113
4.207GlyGlu: 4.207 ± 1.434
3.005GlyPhe: 3.005 ± 0.225
6.01GlyGly: 6.01 ± 2.938
1.803GlyHis: 1.803 ± 1.106
1.803GlyIle: 1.803 ± 1.378
3.606GlyLys: 3.606 ± 0.987
3.005GlyLeu: 3.005 ± 0.954
1.202GlyMet: 1.202 ± 0.843
2.404GlyAsn: 2.404 ± 1.175
1.803GlyPro: 1.803 ± 0.558
2.404GlyGln: 2.404 ± 0.591
3.606GlyArg: 3.606 ± 1.115
4.207GlySer: 4.207 ± 0.52
6.611GlyThr: 6.611 ± 1.498
6.01GlyVal: 6.01 ± 0.755
0.601GlyTrp: 0.601 ± 0.422
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
3.005HisAla: 3.005 ± 0.225
1.202HisCys: 1.202 ± 0.587
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.601HisPhe: 0.601 ± 0.71
1.803HisGly: 1.803 ± 0.959
0.0HisHis: 0.0 ± 0.0
1.803HisIle: 1.803 ± 0.558
1.202HisLys: 1.202 ± 0.587
4.207HisLeu: 4.207 ± 2.329
1.202HisMet: 1.202 ± 1.42
1.202HisAsn: 1.202 ± 0.843
4.207HisPro: 4.207 ± 0.52
0.601HisGln: 0.601 ± 0.422
3.606HisArg: 3.606 ± 1.762
1.803HisSer: 1.803 ± 0.676
2.404HisThr: 2.404 ± 1.462
1.803HisVal: 1.803 ± 0.676
0.601HisTrp: 0.601 ± 0.71
0.601HisTyr: 0.601 ± 0.71
0.0HisXaa: 0.0 ± 0.0
Ile
4.207IleAla: 4.207 ± 1.855
0.601IleCys: 0.601 ± 0.71
1.803IleAsp: 1.803 ± 0.676
3.005IleGlu: 3.005 ± 0.838
0.0IlePhe: 0.0 ± 0.0
4.207IleGly: 4.207 ± 1.032
0.0IleHis: 0.0 ± 0.0
1.202IleIle: 1.202 ± 1.42
1.803IleLys: 1.803 ± 1.25
1.803IleLeu: 1.803 ± 0.959
1.202IleMet: 1.202 ± 0.485
1.202IleAsn: 1.202 ± 0.329
3.005IlePro: 3.005 ± 1.238
2.404IleGln: 2.404 ± 1.058
0.0IleArg: 0.0 ± 0.0
1.803IleSer: 1.803 ± 1.25
4.808IleThr: 4.808 ± 1.302
3.606IleVal: 3.606 ± 0.987
0.601IleTrp: 0.601 ± 0.422
1.202IleTyr: 1.202 ± 0.731
0.0IleXaa: 0.0 ± 0.0
Lys
4.207LysAla: 4.207 ± 1.145
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.202LysGlu: 1.202 ± 0.329
1.803LysPhe: 1.803 ± 0.66
3.005LysGly: 3.005 ± 0.506
1.202LysHis: 1.202 ± 0.731
0.601LysIle: 0.601 ± 0.422
3.005LysLys: 3.005 ± 0.954
3.606LysLeu: 3.606 ± 1.623
0.601LysMet: 0.601 ± 0.369
0.0LysAsn: 0.0 ± 0.0
1.803LysPro: 1.803 ± 0.558
1.803LysGln: 1.803 ± 1.106
2.404LysArg: 2.404 ± 0.276
0.601LysSer: 0.601 ± 0.71
1.202LysThr: 1.202 ± 0.738
4.808LysVal: 4.808 ± 0.435
0.601LysTrp: 0.601 ± 0.369
2.404LysTyr: 2.404 ± 1.175
0.0LysXaa: 0.0 ± 0.0
Leu
8.413LeuAla: 8.413 ± 0.561
1.803LeuCys: 1.803 ± 1.106
4.808LeuAsp: 4.808 ± 0.792
7.812LeuGlu: 7.812 ± 0.771
5.409LeuPhe: 5.409 ± 2.011
4.207LeuGly: 4.207 ± 0.52
1.803LeuHis: 1.803 ± 0.959
1.803LeuIle: 1.803 ± 0.66
3.005LeuLys: 3.005 ± 0.838
7.812LeuLeu: 7.812 ± 0.41
1.202LeuMet: 1.202 ± 0.738
3.005LeuAsn: 3.005 ± 0.225
6.01LeuPro: 6.01 ± 1.629
1.803LeuGln: 1.803 ± 0.676
5.409LeuArg: 5.409 ± 0.276
6.01LeuSer: 6.01 ± 2.735
4.207LeuThr: 4.207 ± 1.712
1.202LeuVal: 1.202 ± 0.587
1.803LeuTrp: 1.803 ± 0.66
4.808LeuTyr: 4.808 ± 2.259
0.0LeuXaa: 0.0 ± 0.0
Met
6.01MetAla: 6.01 ± 1.629
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.202MetGlu: 1.202 ± 0.738
0.0MetPhe: 0.0 ± 0.0
1.803MetGly: 1.803 ± 0.676
1.202MetHis: 1.202 ± 0.329
0.601MetIle: 0.601 ± 0.369
1.202MetLys: 1.202 ± 0.738
0.601MetLeu: 0.601 ± 0.422
0.601MetMet: 0.601 ± 0.369
0.0MetAsn: 0.0 ± 0.0
2.404MetPro: 2.404 ± 1.462
1.202MetGln: 1.202 ± 0.587
1.202MetArg: 1.202 ± 0.587
1.202MetSer: 1.202 ± 0.587
2.404MetThr: 2.404 ± 1.475
1.202MetVal: 1.202 ± 0.329
0.601MetTrp: 0.601 ± 0.369
1.202MetTyr: 1.202 ± 0.329
0.0MetXaa: 0.0 ± 0.0
Asn
6.611AsnAla: 6.611 ± 1.938
0.0AsnCys: 0.0 ± 0.0
3.005AsnAsp: 3.005 ± 0.954
0.601AsnGlu: 0.601 ± 0.422
0.0AsnPhe: 0.0 ± 0.0
3.005AsnGly: 3.005 ± 0.954
0.601AsnHis: 0.601 ± 0.369
1.202AsnIle: 1.202 ± 0.329
1.202AsnLys: 1.202 ± 0.329
4.207AsnLeu: 4.207 ± 1.738
0.0AsnMet: 0.0 ± 0.0
0.601AsnAsn: 0.601 ± 0.369
1.202AsnPro: 1.202 ± 0.843
2.404AsnGln: 2.404 ± 0.276
1.803AsnArg: 1.803 ± 0.558
4.207AsnSer: 4.207 ± 0.385
3.606AsnThr: 3.606 ± 0.823
1.202AsnVal: 1.202 ± 0.738
1.202AsnTrp: 1.202 ± 0.587
0.601AsnTyr: 0.601 ± 0.369
0.0AsnXaa: 0.0 ± 0.0
Pro
8.413ProAla: 8.413 ± 1.04
0.601ProCys: 0.601 ± 0.71
3.606ProAsp: 3.606 ± 0.841
1.803ProGlu: 1.803 ± 0.558
2.404ProPhe: 2.404 ± 0.658
3.606ProGly: 3.606 ± 1.321
1.803ProHis: 1.803 ± 2.131
3.606ProIle: 3.606 ± 0.156
1.202ProLys: 1.202 ± 1.42
5.409ProLeu: 5.409 ± 1.512
0.601ProMet: 0.601 ± 0.369
3.606ProAsn: 3.606 ± 0.987
8.413ProPro: 8.413 ± 2.766
3.005ProGln: 3.005 ± 0.506
3.005ProArg: 3.005 ± 2.108
2.404ProSer: 2.404 ± 0.591
3.606ProThr: 3.606 ± 0.616
4.808ProVal: 4.808 ± 1.451
2.404ProTrp: 2.404 ± 0.658
0.601ProTyr: 0.601 ± 0.422
0.0ProXaa: 0.0 ± 0.0
Gln
3.606GlnAla: 3.606 ± 1.115
0.0GlnCys: 0.0 ± 0.0
1.202GlnAsp: 1.202 ± 0.329
0.601GlnGlu: 0.601 ± 0.71
0.601GlnPhe: 0.601 ± 0.71
1.803GlnGly: 1.803 ± 0.66
0.601GlnHis: 0.601 ± 0.71
2.404GlnIle: 2.404 ± 0.658
0.601GlnLys: 0.601 ± 0.422
2.404GlnLeu: 2.404 ± 0.886
0.0GlnMet: 0.0 ± 0.0
1.202GlnAsn: 1.202 ± 0.329
2.404GlnPro: 2.404 ± 1.475
0.601GlnGln: 0.601 ± 0.369
2.404GlnArg: 2.404 ± 1.113
1.803GlnSer: 1.803 ± 1.265
1.202GlnThr: 1.202 ± 0.738
4.207GlnVal: 4.207 ± 1.905
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
7.812ArgAla: 7.812 ± 1.27
0.601ArgCys: 0.601 ± 0.369
6.611ArgAsp: 6.611 ± 2.94
1.803ArgGlu: 1.803 ± 0.558
4.207ArgPhe: 4.207 ± 0.926
3.606ArgGly: 3.606 ± 1.353
1.202ArgHis: 1.202 ± 1.42
1.202ArgIle: 1.202 ± 0.843
1.803ArgLys: 1.803 ± 0.66
6.611ArgLeu: 6.611 ± 0.618
3.005ArgMet: 3.005 ± 0.691
1.202ArgAsn: 1.202 ± 0.738
4.808ArgPro: 4.808 ± 1.87
1.202ArgGln: 1.202 ± 0.329
8.413ArgArg: 8.413 ± 1.038
2.404ArgSer: 2.404 ± 1.113
2.404ArgThr: 2.404 ± 0.658
4.808ArgVal: 4.808 ± 2.259
1.803ArgTrp: 1.803 ± 0.411
1.202ArgTyr: 1.202 ± 0.738
0.0ArgXaa: 0.0 ± 0.0
Ser
5.409SerAla: 5.409 ± 0.814
0.601SerCys: 0.601 ± 0.422
1.803SerAsp: 1.803 ± 1.265
0.601SerGlu: 0.601 ± 0.422
3.005SerPhe: 3.005 ± 1.238
2.404SerGly: 2.404 ± 0.591
2.404SerHis: 2.404 ± 0.591
4.207SerIle: 4.207 ± 0.52
3.005SerLys: 3.005 ± 1.238
4.808SerLeu: 4.808 ± 2.226
2.404SerMet: 2.404 ± 1.462
3.005SerAsn: 3.005 ± 0.94
3.005SerPro: 3.005 ± 0.506
0.601SerGln: 0.601 ± 0.71
0.601SerArg: 0.601 ± 0.422
5.409SerSer: 5.409 ± 1.584
7.212SerThr: 7.212 ± 1.133
6.611SerVal: 6.611 ± 0.833
1.202SerTrp: 1.202 ± 0.738
2.404SerTyr: 2.404 ± 1.058
0.0SerXaa: 0.0 ± 0.0
Thr
10.216ThrAla: 10.216 ± 0.765
0.601ThrCys: 0.601 ± 0.369
2.404ThrAsp: 2.404 ± 0.886
3.606ThrGlu: 3.606 ± 0.841
1.803ThrPhe: 1.803 ± 0.558
6.611ThrGly: 6.611 ± 1.782
1.803ThrHis: 1.803 ± 0.676
3.606ThrIle: 3.606 ± 0.857
3.606ThrLys: 3.606 ± 0.987
4.207ThrLeu: 4.207 ± 1.434
2.404ThrMet: 2.404 ± 0.591
3.606ThrAsn: 3.606 ± 1.332
3.606ThrPro: 3.606 ± 1.287
1.202ThrGln: 1.202 ± 0.329
4.808ThrArg: 4.808 ± 2.226
4.808ThrSer: 4.808 ± 2.15
5.409ThrThr: 5.409 ± 1.584
3.005ThrVal: 3.005 ± 0.838
1.202ThrTrp: 1.202 ± 0.843
3.005ThrTyr: 3.005 ± 0.94
0.0ThrXaa: 0.0 ± 0.0
Val
7.212ValAla: 7.212 ± 2.362
2.404ValCys: 2.404 ± 0.918
4.207ValAsp: 4.207 ± 1.96
4.808ValGlu: 4.808 ± 1.873
1.803ValPhe: 1.803 ± 0.676
4.808ValGly: 4.808 ± 0.553
3.606ValHis: 3.606 ± 1.558
1.803ValIle: 1.803 ± 0.959
1.202ValLys: 1.202 ± 0.329
7.812ValLeu: 7.812 ± 1.32
1.202ValMet: 1.202 ± 0.777
3.005ValAsn: 3.005 ± 0.954
2.404ValPro: 2.404 ± 0.658
0.0ValGln: 0.0 ± 0.0
6.01ValArg: 6.01 ± 2.236
4.207ValSer: 4.207 ± 1.266
6.01ValThr: 6.01 ± 1.042
4.207ValVal: 4.207 ± 1.145
2.404ValTrp: 2.404 ± 0.918
3.606ValTyr: 3.606 ± 2.051
0.0ValXaa: 0.0 ± 0.0
Trp
3.005TrpAla: 3.005 ± 0.225
0.601TrpCys: 0.601 ± 0.369
1.202TrpAsp: 1.202 ± 0.587
1.202TrpGlu: 1.202 ± 0.738
0.0TrpPhe: 0.0 ± 0.0
1.803TrpGly: 1.803 ± 1.265
0.601TrpHis: 0.601 ± 0.422
0.601TrpIle: 0.601 ± 0.71
0.601TrpLys: 0.601 ± 0.71
1.803TrpLeu: 1.803 ± 1.106
0.0TrpMet: 0.0 ± 0.0
2.404TrpAsn: 2.404 ± 0.918
1.803TrpPro: 1.803 ± 0.959
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.202TrpThr: 1.202 ± 0.329
0.601TrpVal: 0.601 ± 0.422
0.0TrpTrp: 0.0 ± 0.0
0.601TrpTyr: 0.601 ± 0.422
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.005TyrAla: 3.005 ± 0.838
0.601TyrCys: 0.601 ± 0.422
3.005TyrAsp: 3.005 ± 1.821
0.601TyrGlu: 0.601 ± 0.369
1.202TyrPhe: 1.202 ± 0.731
1.803TyrGly: 1.803 ± 0.959
2.404TyrHis: 2.404 ± 2.067
2.404TyrIle: 2.404 ± 1.113
0.0TyrLys: 0.0 ± 0.0
4.207TyrLeu: 4.207 ± 0.52
0.601TyrMet: 0.601 ± 0.369
1.202TyrAsn: 1.202 ± 0.329
0.601TyrPro: 0.601 ± 0.422
0.601TyrGln: 0.601 ± 0.369
2.404TyrArg: 2.404 ± 0.658
3.606TyrSer: 3.606 ± 0.156
2.404TyrThr: 2.404 ± 0.886
1.202TyrVal: 1.202 ± 0.587
0.0TyrTrp: 0.0 ± 0.0
0.601TyrTyr: 0.601 ± 0.369
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1665 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski