Gallid alphaherpesvirus 2

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus

Average proteome isoelectric point is 7.41

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 158 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|Q6R5S6|Q6R5S6_9ALPH LORF11 OS=Gallid alphaherpesvirus 2 OX=10390 GN=LORF11 PE=4 SV=1
MM1 pKa = 7.8EE2 pKa = 5.44NGQLQHH8 pKa = 6.8EE9 pKa = 4.78SLDD12 pKa = 3.76LDD14 pKa = 4.04ADD16 pKa = 3.76AVSIPEE22 pKa = 4.48TISPPIEE29 pKa = 4.24EE30 pKa = 4.76EE31 pKa = 4.17PVLSDD36 pKa = 3.08IDD38 pKa = 3.8EE39 pKa = 4.14QSEE42 pKa = 4.57YY43 pKa = 10.65IHH45 pKa = 6.49LQLEE49 pKa = 4.46SVTRR53 pKa = 11.84YY54 pKa = 10.23NNSALLPTYY63 pKa = 10.58DD64 pKa = 4.9DD65 pKa = 5.15AVDD68 pKa = 4.42PPPSYY73 pKa = 11.22DD74 pKa = 3.47SLSPIHH80 pKa = 6.17NVNNSEE86 pKa = 4.02SCAEE90 pKa = 3.62VDD92 pKa = 3.2LRR94 pKa = 11.84FIIRR98 pKa = 11.84HH99 pKa = 6.15DD100 pKa = 3.51GCAIATLLILFLTVVSATLVTIITEE125 pKa = 4.22TT126 pKa = 3.26

Molecular weight: 13.88 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q19BF7|Q19BF7_9ALPH Uncharacterized protein OS=Gallid alphaherpesvirus 2 OX=10390 GN=MDV012.8 PE=4 SV=1
MM1 pKa = 7.77CNHH4 pKa = 5.81SHH6 pKa = 4.57VQKK9 pKa = 9.76TGSQTPIDD17 pKa = 4.01INHH20 pKa = 6.69NGYY23 pKa = 8.88QHH25 pKa = 6.37TFRR28 pKa = 11.84INCVSKK34 pKa = 11.02LGLEE38 pKa = 3.97LRR40 pKa = 11.84IIQSGNSMLRR50 pKa = 11.84AFHH53 pKa = 6.93AGMPARR59 pKa = 11.84RR60 pKa = 11.84ALSTRR65 pKa = 11.84LRR67 pKa = 11.84LLRR70 pKa = 11.84TGEE73 pKa = 3.99CGKK76 pKa = 10.51RR77 pKa = 11.84PTYY80 pKa = 10.05DD81 pKa = 3.01VCEE84 pKa = 4.24KK85 pKa = 10.61SGSRR89 pKa = 11.84EE90 pKa = 3.38KK91 pKa = 11.05SRR93 pKa = 11.84IYY95 pKa = 10.48PFF97 pKa = 3.94

Molecular weight: 11.03 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

156

2

158

50554

20

3357

320.0

35.78

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.101 ± 0.193

2.589 ± 0.137

5.145 ± 0.194

4.919 ± 0.148

3.889 ± 0.156

5.723 ± 0.162

2.603 ± 0.09

6.447 ± 0.207

4.136 ± 0.19

9.376 ± 0.233

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.672 ± 0.101

4.287 ± 0.115

5.568 ± 0.382

2.698 ± 0.09

6.917 ± 0.237

8.872 ± 0.232

6.575 ± 0.114

5.942 ± 0.112

1.139 ± 0.057

3.4 ± 0.104
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski