Amino acid dipepetide frequency for Grapevine red blotch virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.687AlaAla: 3.687 ± 1.374
0.922AlaCys: 0.922 ± 1.045
0.922AlaAsp: 0.922 ± 0.672
2.765AlaGlu: 2.765 ± 1.186
2.765AlaPhe: 2.765 ± 2.274
1.843AlaGly: 1.843 ± 0.932
0.0AlaHis: 0.0 ± 0.0
3.687AlaIle: 3.687 ± 1.607
1.843AlaLys: 1.843 ± 1.342
8.295AlaLeu: 8.295 ± 1.595
0.0AlaMet: 0.0 ± 0.0
2.765AlaAsn: 2.765 ± 1.471
0.922AlaPro: 0.922 ± 0.672
3.687AlaGln: 3.687 ± 1.303
1.843AlaArg: 1.843 ± 1.128
4.608AlaSer: 4.608 ± 1.229
1.843AlaThr: 1.843 ± 1.503
0.922AlaVal: 0.922 ± 0.758
0.922AlaTrp: 0.922 ± 0.672
0.922AlaTyr: 0.922 ± 0.672
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.922CysCys: 0.922 ± 1.045
1.843CysAsp: 1.843 ± 2.091
1.843CysGlu: 1.843 ± 1.143
0.0CysPhe: 0.0 ± 0.0
0.922CysGly: 0.922 ± 1.045
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.922CysLys: 0.922 ± 0.752
4.608CysLeu: 4.608 ± 3.155
0.0CysMet: 0.0 ± 0.0
1.843CysAsn: 1.843 ± 1.043
0.922CysPro: 0.922 ± 0.672
1.843CysGln: 1.843 ± 1.03
0.922CysArg: 0.922 ± 1.045
2.765CysSer: 2.765 ± 2.258
0.922CysThr: 0.922 ± 1.055
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.608AspAla: 4.608 ± 1.64
0.922AspCys: 0.922 ± 1.045
8.295AspAsp: 8.295 ± 3.387
4.608AspGlu: 4.608 ± 2.181
2.765AspPhe: 2.765 ± 1.471
3.687AspGly: 3.687 ± 1.976
0.0AspHis: 0.0 ± 0.0
7.373AspIle: 7.373 ± 2.344
1.843AspLys: 1.843 ± 1.222
1.843AspLeu: 1.843 ± 1.228
0.922AspMet: 0.922 ± 0.593
2.765AspAsn: 2.765 ± 1.645
0.922AspPro: 0.922 ± 0.758
1.843AspGln: 1.843 ± 1.228
4.608AspArg: 4.608 ± 1.479
2.765AspSer: 2.765 ± 2.126
0.922AspThr: 0.922 ± 0.672
5.53AspVal: 5.53 ± 1.329
0.922AspTrp: 0.922 ± 1.045
3.687AspTyr: 3.687 ± 2.445
0.0AspXaa: 0.0 ± 0.0
Glu
2.765GluAla: 2.765 ± 2.058
0.922GluCys: 0.922 ± 1.045
3.687GluAsp: 3.687 ± 3.063
8.295GluGlu: 8.295 ± 3.111
4.608GluPhe: 4.608 ± 2.181
2.765GluGly: 2.765 ± 0.989
0.922GluHis: 0.922 ± 0.672
1.843GluIle: 1.843 ± 0.929
5.53GluLys: 5.53 ± 2.823
7.373GluLeu: 7.373 ± 3.172
2.765GluMet: 2.765 ± 1.762
2.765GluAsn: 2.765 ± 1.73
3.687GluPro: 3.687 ± 1.428
0.922GluGln: 0.922 ± 0.672
2.765GluArg: 2.765 ± 1.193
2.765GluSer: 2.765 ± 1.186
2.765GluThr: 2.765 ± 0.889
1.843GluVal: 1.843 ± 2.109
0.922GluTrp: 0.922 ± 1.045
1.843GluTyr: 1.843 ± 0.955
0.0GluXaa: 0.0 ± 0.0
Phe
3.687PheAla: 3.687 ± 1.273
1.843PheCys: 1.843 ± 1.342
0.922PheAsp: 0.922 ± 0.672
0.922PheGlu: 0.922 ± 1.045
3.687PhePhe: 3.687 ± 1.569
2.765PheGly: 2.765 ± 1.193
1.843PheHis: 1.843 ± 0.929
0.922PheIle: 0.922 ± 0.831
3.687PheLys: 3.687 ± 1.472
5.53PheLeu: 5.53 ± 2.193
0.0PheMet: 0.0 ± 0.0
3.687PheAsn: 3.687 ± 1.247
0.922PhePro: 0.922 ± 0.758
3.687PheGln: 3.687 ± 1.601
1.843PheArg: 1.843 ± 1.516
0.922PheSer: 0.922 ± 0.752
1.843PheThr: 1.843 ± 1.128
1.843PheVal: 1.843 ± 1.195
0.922PheTrp: 0.922 ± 0.758
0.922PheTyr: 0.922 ± 0.758
0.0PheXaa: 0.0 ± 0.0
Gly
0.922GlyAla: 0.922 ± 0.758
1.843GlyCys: 1.843 ± 1.143
4.608GlyAsp: 4.608 ± 1.867
5.53GlyGlu: 5.53 ± 3.667
0.0GlyPhe: 0.0 ± 0.0
4.608GlyGly: 4.608 ± 2.271
0.922GlyHis: 0.922 ± 0.758
5.53GlyIle: 5.53 ± 1.299
1.843GlyLys: 1.843 ± 0.955
4.608GlyLeu: 4.608 ± 1.916
0.0GlyMet: 0.0 ± 0.0
1.843GlyAsn: 1.843 ± 1.128
2.765GlyPro: 2.765 ± 1.078
0.922GlyGln: 0.922 ± 0.831
1.843GlyArg: 1.843 ± 1.516
6.452GlySer: 6.452 ± 1.551
3.687GlyThr: 3.687 ± 2.211
2.765GlyVal: 2.765 ± 2.274
0.0GlyTrp: 0.0 ± 0.0
0.922GlyTyr: 0.922 ± 1.055
0.0GlyXaa: 0.0 ± 0.0
His
2.765HisAla: 2.765 ± 1.471
0.922HisCys: 0.922 ± 1.045
0.922HisAsp: 0.922 ± 0.758
0.0HisGlu: 0.0 ± 0.0
0.922HisPhe: 0.922 ± 0.672
2.765HisGly: 2.765 ± 0.889
0.0HisHis: 0.0 ± 0.0
0.922HisIle: 0.922 ± 0.672
0.922HisLys: 0.922 ± 0.672
1.843HisLeu: 1.843 ± 1.343
0.922HisMet: 0.922 ± 0.831
1.843HisAsn: 1.843 ± 1.043
0.922HisPro: 0.922 ± 0.672
1.843HisGln: 1.843 ± 0.929
1.843HisArg: 1.843 ± 1.195
2.765HisSer: 2.765 ± 1.193
1.843HisThr: 1.843 ± 0.929
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.922HisTyr: 0.922 ± 0.672
0.0HisXaa: 0.0 ± 0.0
Ile
2.765IleAla: 2.765 ± 1.233
0.922IleCys: 0.922 ± 1.045
4.608IleAsp: 4.608 ± 2.142
1.843IleGlu: 1.843 ± 1.03
4.608IlePhe: 4.608 ± 2.261
0.922IleGly: 0.922 ± 0.672
1.843IleHis: 1.843 ± 0.955
3.687IleIle: 3.687 ± 1.635
1.843IleLys: 1.843 ± 1.143
3.687IleLeu: 3.687 ± 1.582
0.0IleMet: 0.0 ± 0.0
0.922IleAsn: 0.922 ± 0.672
5.53IlePro: 5.53 ± 2.684
0.922IleGln: 0.922 ± 0.831
1.843IleArg: 1.843 ± 0.932
6.452IleSer: 6.452 ± 2.867
7.373IleThr: 7.373 ± 3.337
2.765IleVal: 2.765 ± 1.233
0.0IleTrp: 0.0 ± 0.0
3.687IleTyr: 3.687 ± 1.366
0.0IleXaa: 0.0 ± 0.0
Lys
3.687LysAla: 3.687 ± 2.189
0.922LysCys: 0.922 ± 1.045
2.765LysAsp: 2.765 ± 1.863
5.53LysGlu: 5.53 ± 1.77
1.843LysPhe: 1.843 ± 0.929
1.843LysGly: 1.843 ± 1.03
3.687LysHis: 3.687 ± 1.618
2.765LysIle: 2.765 ± 1.628
9.217LysLys: 9.217 ± 2.369
2.765LysLeu: 2.765 ± 0.896
0.0LysMet: 0.0 ± 0.0
2.765LysAsn: 2.765 ± 0.889
3.687LysPro: 3.687 ± 1.472
4.608LysGln: 4.608 ± 1.604
7.373LysArg: 7.373 ± 1.74
3.687LysSer: 3.687 ± 2.077
6.452LysThr: 6.452 ± 2.485
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
0.922LysTyr: 0.922 ± 0.752
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
0.922LeuCys: 0.922 ± 0.752
10.138LeuAsp: 10.138 ± 2.593
4.608LeuGlu: 4.608 ± 2.35
3.687LeuPhe: 3.687 ± 1.23
7.373LeuGly: 7.373 ± 1.084
2.765LeuHis: 2.765 ± 1.193
4.608LeuIle: 4.608 ± 1.798
5.53LeuLys: 5.53 ± 0.557
9.217LeuLeu: 9.217 ± 3.884
0.0LeuMet: 0.0 ± 0.0
7.373LeuAsn: 7.373 ± 1.647
9.217LeuPro: 9.217 ± 3.631
2.765LeuGln: 2.765 ± 1.392
4.608LeuArg: 4.608 ± 1.867
2.765LeuSer: 2.765 ± 1.256
7.373LeuThr: 7.373 ± 1.364
4.608LeuVal: 4.608 ± 1.356
2.765LeuTrp: 2.765 ± 1.196
5.53LeuTyr: 5.53 ± 2.282
0.0LeuXaa: 0.0 ± 0.0
Met
1.843MetAla: 1.843 ± 0.929
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.922MetGlu: 0.922 ± 1.055
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.922MetIle: 0.922 ± 0.758
0.922MetLys: 0.922 ± 0.758
0.922MetLeu: 0.922 ± 0.752
0.0MetMet: 0.0 ± 1.0
0.922MetAsn: 0.922 ± 0.752
0.922MetPro: 0.922 ± 0.831
0.922MetGln: 0.922 ± 0.752
0.0MetArg: 0.0 ± 0.0
0.922MetSer: 0.922 ± 0.831
0.0MetThr: 0.0 ± 0.0
2.765MetVal: 2.765 ± 1.225
0.0MetTrp: 0.0 ± 0.0
0.922MetTyr: 0.922 ± 0.758
0.0MetXaa: 0.0 ± 0.0
Asn
0.922AsnAla: 0.922 ± 0.672
0.0AsnCys: 0.0 ± 0.0
4.608AsnAsp: 4.608 ± 1.946
3.687AsnGlu: 3.687 ± 1.115
2.765AsnPhe: 2.765 ± 1.374
2.765AsnGly: 2.765 ± 1.503
0.0AsnHis: 0.0 ± 0.0
4.608AsnIle: 4.608 ± 1.533
1.843AsnLys: 1.843 ± 1.128
3.687AsnLeu: 3.687 ± 2.686
0.0AsnMet: 0.0 ± 0.0
3.687AsnAsn: 3.687 ± 1.979
2.765AsnPro: 2.765 ± 1.076
1.843AsnGln: 1.843 ± 0.929
4.608AsnArg: 4.608 ± 2.123
7.373AsnSer: 7.373 ± 2.44
3.687AsnThr: 3.687 ± 2.415
0.922AsnVal: 0.922 ± 0.758
1.843AsnTrp: 1.843 ± 1.043
2.765AsnTyr: 2.765 ± 1.582
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
2.765ProCys: 2.765 ± 1.086
2.765ProAsp: 2.765 ± 2.125
3.687ProGlu: 3.687 ± 1.764
0.922ProPhe: 0.922 ± 0.752
2.765ProGly: 2.765 ± 1.244
3.687ProHis: 3.687 ± 1.273
4.608ProIle: 4.608 ± 2.326
3.687ProLys: 3.687 ± 1.459
2.765ProLeu: 2.765 ± 1.359
0.0ProMet: 0.0 ± 0.0
0.922ProAsn: 0.922 ± 0.672
3.687ProPro: 3.687 ± 1.303
1.843ProGln: 1.843 ± 0.884
2.765ProArg: 2.765 ± 1.193
6.452ProSer: 6.452 ± 2.307
6.452ProThr: 6.452 ± 1.701
1.843ProVal: 1.843 ± 0.884
0.922ProTrp: 0.922 ± 0.752
1.843ProTyr: 1.843 ± 0.929
0.0ProXaa: 0.0 ± 0.0
Gln
0.922GlnAla: 0.922 ± 0.672
0.922GlnCys: 0.922 ± 0.672
0.922GlnAsp: 0.922 ± 1.045
3.687GlnGlu: 3.687 ± 1.002
2.765GlnPhe: 2.765 ± 1.078
0.0GlnGly: 0.0 ± 0.0
2.765GlnHis: 2.765 ± 1.392
0.922GlnIle: 0.922 ± 0.831
2.765GlnLys: 2.765 ± 1.14
3.687GlnLeu: 3.687 ± 1.764
0.922GlnMet: 0.922 ± 0.686
2.765GlnAsn: 2.765 ± 1.392
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
6.452GlnArg: 6.452 ± 1.734
2.765GlnSer: 2.765 ± 1.63
1.843GlnThr: 1.843 ± 0.932
0.922GlnVal: 0.922 ± 1.055
1.843GlnTrp: 1.843 ± 0.955
1.843GlnTyr: 1.843 ± 0.955
0.0GlnXaa: 0.0 ± 0.0
Arg
1.843ArgAla: 1.843 ± 1.516
1.843ArgCys: 1.843 ± 2.109
1.843ArgAsp: 1.843 ± 1.222
0.922ArgGlu: 0.922 ± 0.672
1.843ArgPhe: 1.843 ± 1.516
0.922ArgGly: 0.922 ± 1.055
0.922ArgHis: 0.922 ± 1.045
3.687ArgIle: 3.687 ± 1.582
6.452ArgLys: 6.452 ± 2.008
6.452ArgLeu: 6.452 ± 1.982
0.0ArgMet: 0.0 ± 0.0
5.53ArgAsn: 5.53 ± 2.016
4.608ArgPro: 4.608 ± 2.012
2.765ArgGln: 2.765 ± 0.896
15.668ArgArg: 15.668 ± 6.234
6.452ArgSer: 6.452 ± 2.325
2.765ArgThr: 2.765 ± 1.615
4.608ArgVal: 4.608 ± 1.867
0.0ArgTrp: 0.0 ± 0.0
0.922ArgTyr: 0.922 ± 1.045
0.0ArgXaa: 0.0 ± 0.0
Ser
5.53SerAla: 5.53 ± 2.354
0.922SerCys: 0.922 ± 1.045
3.687SerAsp: 3.687 ± 2.211
4.608SerGlu: 4.608 ± 2.651
2.765SerPhe: 2.765 ± 0.889
5.53SerGly: 5.53 ± 2.199
1.843SerHis: 1.843 ± 0.929
1.843SerIle: 1.843 ± 1.043
7.373SerLys: 7.373 ± 2.506
6.452SerLeu: 6.452 ± 2.755
2.765SerMet: 2.765 ± 1.551
2.765SerAsn: 2.765 ± 2.493
3.687SerPro: 3.687 ± 2.539
3.687SerGln: 3.687 ± 2.684
5.53SerArg: 5.53 ± 2.606
15.668SerSer: 15.668 ± 4.934
3.687SerThr: 3.687 ± 1.942
3.687SerVal: 3.687 ± 1.985
0.0SerTrp: 0.0 ± 0.0
2.765SerTyr: 2.765 ± 1.076
0.0SerXaa: 0.0 ± 0.0
Thr
0.922ThrAla: 0.922 ± 0.672
1.843ThrCys: 1.843 ± 1.342
2.765ThrAsp: 2.765 ± 1.503
2.765ThrGlu: 2.765 ± 2.14
2.765ThrPhe: 2.765 ± 1.086
6.452ThrGly: 6.452 ± 3.66
0.922ThrHis: 0.922 ± 0.752
1.843ThrIle: 1.843 ± 0.932
3.687ThrLys: 3.687 ± 2.228
8.295ThrLeu: 8.295 ± 1.735
1.843ThrMet: 1.843 ± 1.503
2.765ThrAsn: 2.765 ± 1.73
6.452ThrPro: 6.452 ± 2.291
0.922ThrGln: 0.922 ± 0.752
0.922ThrArg: 0.922 ± 0.758
3.687ThrSer: 3.687 ± 3.324
1.843ThrThr: 1.843 ± 1.134
4.608ThrVal: 4.608 ± 0.835
1.843ThrTrp: 1.843 ± 0.929
3.687ThrTyr: 3.687 ± 1.251
0.0ThrXaa: 0.0 ± 0.0
Val
4.608ValAla: 4.608 ± 1.664
0.0ValCys: 0.0 ± 0.0
1.843ValAsp: 1.843 ± 1.195
3.687ValGlu: 3.687 ± 1.569
0.0ValPhe: 0.0 ± 0.0
2.765ValGly: 2.765 ± 1.193
0.922ValHis: 0.922 ± 0.672
1.843ValIle: 1.843 ± 1.03
2.765ValLys: 2.765 ± 1.306
7.373ValLeu: 7.373 ± 2.384
1.843ValMet: 1.843 ± 1.134
1.843ValAsn: 1.843 ± 1.516
0.0ValPro: 0.0 ± 0.0
2.765ValGln: 2.765 ± 1.392
1.843ValArg: 1.843 ± 0.884
4.608ValSer: 4.608 ± 2.123
3.687ValThr: 3.687 ± 1.989
3.687ValVal: 3.687 ± 2.211
0.0ValTrp: 0.0 ± 0.0
1.843ValTyr: 1.843 ± 1.313
0.0ValXaa: 0.0 ± 0.0
Trp
1.843TrpAla: 1.843 ± 1.503
0.922TrpCys: 0.922 ± 0.752
0.0TrpAsp: 0.0 ± 0.0
0.922TrpGlu: 0.922 ± 1.045
1.843TrpPhe: 1.843 ± 2.091
0.0TrpGly: 0.0 ± 0.0
0.922TrpHis: 0.922 ± 0.752
1.843TrpIle: 1.843 ± 0.929
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.922TrpAsn: 0.922 ± 0.672
0.922TrpPro: 0.922 ± 0.672
0.0TrpGln: 0.0 ± 0.0
0.922TrpArg: 0.922 ± 1.055
0.0TrpSer: 0.0 ± 0.0
0.922TrpThr: 0.922 ± 0.672
0.922TrpVal: 0.922 ± 0.672
0.0TrpTrp: 0.0 ± 0.0
0.922TrpTyr: 0.922 ± 0.831
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.843TyrAla: 1.843 ± 0.929
0.0TyrCys: 0.0 ± 0.0
3.687TyrAsp: 3.687 ± 3.134
0.922TyrGlu: 0.922 ± 0.831
1.843TyrPhe: 1.843 ± 0.884
0.922TyrGly: 0.922 ± 1.055
0.922TyrHis: 0.922 ± 0.672
2.765TyrIle: 2.765 ± 2.255
1.843TyrLys: 1.843 ± 1.313
6.452TyrLeu: 6.452 ± 1.761
0.922TyrMet: 0.922 ± 0.697
3.687TyrAsn: 3.687 ± 1.002
1.843TyrPro: 1.843 ± 1.343
0.922TyrGln: 0.922 ± 0.672
1.843TyrArg: 1.843 ± 1.043
0.922TyrSer: 0.922 ± 1.045
0.922TyrThr: 0.922 ± 0.831
3.687TyrVal: 3.687 ± 2.686
0.922TyrTrp: 0.922 ± 0.752
1.843TyrTyr: 1.843 ± 0.955
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski