Amino acid dipepetide frequency for Desmodium mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.472AlaAla: 2.472 ± 1.494
1.236AlaCys: 1.236 ± 0.616
1.854AlaAsp: 1.854 ± 1.215
4.326AlaGlu: 4.326 ± 1.326
3.09AlaPhe: 3.09 ± 1.357
3.09AlaGly: 3.09 ± 1.263
0.618AlaHis: 0.618 ± 0.693
2.472AlaIle: 2.472 ± 1.494
3.09AlaLys: 3.09 ± 1.328
5.562AlaLeu: 5.562 ± 1.809
1.854AlaMet: 1.854 ± 0.879
1.236AlaAsn: 1.236 ± 0.967
3.708AlaPro: 3.708 ± 1.151
4.326AlaGln: 4.326 ± 1.973
3.09AlaArg: 3.09 ± 1.953
4.944AlaSer: 4.944 ± 1.124
4.326AlaThr: 4.326 ± 1.713
2.472AlaVal: 2.472 ± 1.015
1.854AlaTrp: 1.854 ± 0.796
0.618AlaTyr: 0.618 ± 0.528
0.0AlaXaa: 0.0 ± 0.0
Cys
1.236CysAla: 1.236 ± 0.967
0.0CysCys: 0.0 ± 0.0
1.854CysAsp: 1.854 ± 1.187
0.618CysGlu: 0.618 ± 0.54
0.618CysPhe: 0.618 ± 0.708
1.236CysGly: 1.236 ± 0.751
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.236CysLys: 1.236 ± 1.081
2.472CysLeu: 2.472 ± 1.139
1.236CysMet: 1.236 ± 0.858
1.236CysAsn: 1.236 ± 0.604
1.236CysPro: 1.236 ± 1.056
1.236CysGln: 1.236 ± 0.967
1.236CysArg: 1.236 ± 1.385
3.09CysSer: 3.09 ± 2.059
1.236CysThr: 1.236 ± 0.86
3.09CysVal: 3.09 ± 0.939
0.0CysTrp: 0.0 ± 0.0
0.618CysTyr: 0.618 ± 0.528
0.0CysXaa: 0.0 ± 0.0
Asp
2.472AspAla: 2.472 ± 0.987
1.854AspCys: 1.854 ± 0.79
2.472AspAsp: 2.472 ± 0.754
1.854AspGlu: 1.854 ± 1.689
1.854AspPhe: 1.854 ± 1.049
2.472AspGly: 2.472 ± 1.419
1.854AspHis: 1.854 ± 0.864
3.708AspIle: 3.708 ± 1.175
1.236AspLys: 1.236 ± 0.604
3.708AspLeu: 3.708 ± 1.476
1.236AspMet: 1.236 ± 0.556
1.854AspAsn: 1.854 ± 1.09
1.854AspPro: 1.854 ± 0.83
2.472AspGln: 2.472 ± 0.961
1.854AspArg: 1.854 ± 1.09
4.944AspSer: 4.944 ± 0.834
3.708AspThr: 3.708 ± 0.988
2.472AspVal: 2.472 ± 1.107
1.236AspTrp: 1.236 ± 0.967
2.472AspTyr: 2.472 ± 0.731
0.0AspXaa: 0.0 ± 0.0
Glu
4.326GluAla: 4.326 ± 2.039
0.618GluCys: 0.618 ± 0.708
3.09GluAsp: 3.09 ± 1.145
3.708GluGlu: 3.708 ± 1.353
1.236GluPhe: 1.236 ± 0.604
4.326GluGly: 4.326 ± 1.302
1.854GluHis: 1.854 ± 1.037
1.854GluIle: 1.854 ± 1.629
0.618GluLys: 0.618 ± 0.492
4.944GluLeu: 4.944 ± 1.639
0.0GluMet: 0.0 ± 0.0
1.854GluAsn: 1.854 ± 1.137
3.09GluPro: 3.09 ± 1.12
4.326GluGln: 4.326 ± 0.772
4.326GluArg: 4.326 ± 1.94
2.472GluSer: 2.472 ± 1.07
3.09GluThr: 3.09 ± 1.11
1.236GluVal: 1.236 ± 0.751
0.618GluTrp: 0.618 ± 0.483
3.09GluTyr: 3.09 ± 1.396
0.0GluXaa: 0.0 ± 0.0
Phe
1.854PheAla: 1.854 ± 0.669
1.236PheCys: 1.236 ± 0.687
3.09PheAsp: 3.09 ± 1.084
0.618PheGlu: 0.618 ± 0.483
1.854PhePhe: 1.854 ± 0.767
1.854PheGly: 1.854 ± 0.879
0.0PheHis: 0.0 ± 0.0
1.236PheIle: 1.236 ± 0.584
3.708PheLys: 3.708 ± 1.677
3.09PheLeu: 3.09 ± 1.097
0.618PheMet: 0.618 ± 0.483
3.09PheAsn: 3.09 ± 1.243
2.472PhePro: 2.472 ± 1.644
2.472PheGln: 2.472 ± 1.03
2.472PheArg: 2.472 ± 1.247
3.708PheSer: 3.708 ± 1.047
3.09PheThr: 3.09 ± 0.858
3.09PheVal: 3.09 ± 2.06
0.618PheTrp: 0.618 ± 0.492
2.472PheTyr: 2.472 ± 0.586
0.0PheXaa: 0.0 ± 0.0
Gly
3.708GlyAla: 3.708 ± 1.169
2.472GlyCys: 2.472 ± 0.686
3.708GlyAsp: 3.708 ± 1.328
4.326GlyGlu: 4.326 ± 1.134
1.236GlyPhe: 1.236 ± 0.887
3.09GlyGly: 3.09 ± 1.135
1.236GlyHis: 1.236 ± 0.604
0.618GlyIle: 0.618 ± 0.483
4.944GlyLys: 4.944 ± 1.901
3.09GlyLeu: 3.09 ± 1.404
0.0GlyMet: 0.0 ± 0.517
3.09GlyAsn: 3.09 ± 1.224
2.472GlyPro: 2.472 ± 0.586
1.236GlyGln: 1.236 ± 1.081
3.09GlyArg: 3.09 ± 1.105
6.799GlySer: 6.799 ± 1.32
1.236GlyThr: 1.236 ± 0.687
6.18GlyVal: 6.18 ± 2.286
0.0GlyTrp: 0.0 ± 0.0
1.236GlyTyr: 1.236 ± 1.057
0.0GlyXaa: 0.0 ± 0.0
His
0.618HisAla: 0.618 ± 0.54
1.854HisCys: 1.854 ± 1.002
1.854HisAsp: 1.854 ± 1.112
1.236HisGlu: 1.236 ± 0.757
0.618HisPhe: 0.618 ± 0.483
0.618HisGly: 0.618 ± 0.528
0.618HisHis: 0.618 ± 0.528
1.854HisIle: 1.854 ± 1.569
1.854HisLys: 1.854 ± 1.048
3.09HisLeu: 3.09 ± 1.452
0.0HisMet: 0.0 ± 0.0
3.09HisAsn: 3.09 ± 1.727
1.236HisPro: 1.236 ± 0.737
1.236HisGln: 1.236 ± 0.687
0.618HisArg: 0.618 ± 0.54
3.708HisSer: 3.708 ± 1.73
3.09HisThr: 3.09 ± 1.674
3.708HisVal: 3.708 ± 1.406
0.0HisTrp: 0.0 ± 0.0
2.472HisTyr: 2.472 ± 1.208
0.0HisXaa: 0.0 ± 0.0
Ile
1.854IleAla: 1.854 ± 0.83
0.0IleCys: 0.0 ± 0.0
2.472IleAsp: 2.472 ± 1.412
1.854IleGlu: 1.854 ± 1.075
3.09IlePhe: 3.09 ± 2.417
4.326IleGly: 4.326 ± 1.305
1.236IleHis: 1.236 ± 0.757
1.236IleIle: 1.236 ± 0.604
6.799IleLys: 6.799 ± 1.275
1.854IleLeu: 1.854 ± 0.868
1.854IleMet: 1.854 ± 0.767
2.472IleAsn: 2.472 ± 1.103
2.472IlePro: 2.472 ± 0.884
3.708IleGln: 3.708 ± 1.66
4.326IleArg: 4.326 ± 1.41
4.944IleSer: 4.944 ± 1.704
2.472IleThr: 2.472 ± 0.979
2.472IleVal: 2.472 ± 0.953
1.236IleTrp: 1.236 ± 0.863
2.472IleTyr: 2.472 ± 0.969
0.0IleXaa: 0.0 ± 0.0
Lys
3.708LysAla: 3.708 ± 1.734
3.708LysCys: 3.708 ± 1.174
3.708LysAsp: 3.708 ± 1.954
4.944LysGlu: 4.944 ± 2.788
1.854LysPhe: 1.854 ± 0.822
3.708LysGly: 3.708 ± 1.032
3.09LysHis: 3.09 ± 0.923
2.472LysIle: 2.472 ± 1.056
1.854LysLys: 1.854 ± 1.054
3.09LysLeu: 3.09 ± 1.486
1.854LysMet: 1.854 ± 0.971
2.472LysAsn: 2.472 ± 1.08
3.09LysPro: 3.09 ± 0.851
1.236LysGln: 1.236 ± 0.616
4.326LysArg: 4.326 ± 2.384
6.18LysSer: 6.18 ± 1.471
1.236LysThr: 1.236 ± 0.967
5.562LysVal: 5.562 ± 1.392
0.0LysTrp: 0.0 ± 0.0
3.09LysTyr: 3.09 ± 1.112
0.0LysXaa: 0.0 ± 0.0
Leu
3.09LeuAla: 3.09 ± 0.921
1.854LeuCys: 1.854 ± 1.057
3.09LeuAsp: 3.09 ± 0.858
5.562LeuGlu: 5.562 ± 1.483
2.472LeuPhe: 2.472 ± 0.731
2.472LeuGly: 2.472 ± 1.015
3.09LeuHis: 3.09 ± 1.149
3.09LeuIle: 3.09 ± 1.166
5.562LeuLys: 5.562 ± 1.982
4.326LeuLeu: 4.326 ± 1.937
1.854LeuMet: 1.854 ± 0.613
2.472LeuAsn: 2.472 ± 1.029
4.944LeuPro: 4.944 ± 1.37
3.09LeuGln: 3.09 ± 0.955
5.562LeuArg: 5.562 ± 2.922
6.18LeuSer: 6.18 ± 1.832
9.271LeuThr: 9.271 ± 1.792
4.326LeuVal: 4.326 ± 1.371
1.236LeuTrp: 1.236 ± 1.484
1.236LeuTyr: 1.236 ± 0.86
0.0LeuXaa: 0.0 ± 0.0
Met
1.236MetAla: 1.236 ± 0.665
0.618MetCys: 0.618 ± 0.679
2.472MetAsp: 2.472 ± 0.788
1.854MetGlu: 1.854 ± 1.342
2.472MetPhe: 2.472 ± 1.651
2.472MetGly: 2.472 ± 1.08
1.236MetHis: 1.236 ± 0.985
0.0MetIle: 0.0 ± 0.0
1.236MetLys: 1.236 ± 0.663
1.236MetLeu: 1.236 ± 0.86
0.0MetMet: 0.0 ± 0.0
1.236MetAsn: 1.236 ± 1.417
0.618MetPro: 0.618 ± 0.483
0.0MetGln: 0.0 ± 0.0
1.854MetArg: 1.854 ± 0.745
1.236MetSer: 1.236 ± 0.665
0.618MetThr: 0.618 ± 0.54
0.618MetVal: 0.618 ± 0.528
1.854MetTrp: 1.854 ± 0.686
0.618MetTyr: 0.618 ± 0.54
0.0MetXaa: 0.0 ± 0.0
Asn
6.799AsnAla: 6.799 ± 2.64
1.236AsnCys: 1.236 ± 0.887
1.236AsnAsp: 1.236 ± 0.967
1.236AsnGlu: 1.236 ± 0.616
0.618AsnPhe: 0.618 ± 0.528
0.618AsnGly: 0.618 ± 0.742
4.326AsnHis: 4.326 ± 2.089
3.708AsnIle: 3.708 ± 1.307
1.854AsnLys: 1.854 ± 0.669
1.854AsnLeu: 1.854 ± 0.977
1.236AsnMet: 1.236 ± 1.031
3.09AsnAsn: 3.09 ± 1.243
2.472AsnPro: 2.472 ± 1.01
3.708AsnGln: 3.708 ± 1.295
0.618AsnArg: 0.618 ± 0.54
1.236AsnSer: 1.236 ± 0.863
1.854AsnThr: 1.854 ± 1.389
6.18AsnVal: 6.18 ± 1.672
0.0AsnTrp: 0.0 ± 0.0
1.854AsnTyr: 1.854 ± 0.67
0.0AsnXaa: 0.0 ± 0.0
Pro
1.854ProAla: 1.854 ± 1.259
1.854ProCys: 1.854 ± 1.099
0.618ProAsp: 0.618 ± 0.54
2.472ProGlu: 2.472 ± 0.734
3.09ProPhe: 3.09 ± 1.279
1.854ProGly: 1.854 ± 1.477
2.472ProHis: 2.472 ± 1.127
3.09ProIle: 3.09 ± 1.395
4.326ProLys: 4.326 ± 1.57
5.562ProLeu: 5.562 ± 1.207
3.09ProMet: 3.09 ± 1.064
1.236ProAsn: 1.236 ± 0.687
2.472ProPro: 2.472 ± 2.178
1.236ProGln: 1.236 ± 1.023
2.472ProArg: 2.472 ± 0.968
4.326ProSer: 4.326 ± 1.921
4.944ProThr: 4.944 ± 0.858
3.708ProVal: 3.708 ± 0.722
0.618ProTrp: 0.618 ± 0.492
2.472ProTyr: 2.472 ± 1.202
0.0ProXaa: 0.0 ± 0.0
Gln
2.472GlnAla: 2.472 ± 0.961
0.618GlnCys: 0.618 ± 0.679
2.472GlnAsp: 2.472 ± 0.854
1.854GlnGlu: 1.854 ± 1.099
3.09GlnPhe: 3.09 ± 1.11
4.326GlnGly: 4.326 ± 1.35
1.854GlnHis: 1.854 ± 1.319
3.708GlnIle: 3.708 ± 1.55
1.236GlnLys: 1.236 ± 0.967
3.708GlnLeu: 3.708 ± 1.102
0.0GlnMet: 0.0 ± 0.0
1.236GlnAsn: 1.236 ± 0.967
3.09GlnPro: 3.09 ± 1.563
1.236GlnGln: 1.236 ± 0.604
1.854GlnArg: 1.854 ± 0.79
3.708GlnSer: 3.708 ± 0.751
3.09GlnThr: 3.09 ± 1.314
2.472GlnVal: 2.472 ± 1.085
0.0GlnTrp: 0.0 ± 0.0
1.236GlnTyr: 1.236 ± 0.687
0.0GlnXaa: 0.0 ± 0.0
Arg
4.944ArgAla: 4.944 ± 1.396
1.854ArgCys: 1.854 ± 1.347
2.472ArgAsp: 2.472 ± 1.02
2.472ArgGlu: 2.472 ± 1.571
5.562ArgPhe: 5.562 ± 2.189
4.326ArgGly: 4.326 ± 0.95
1.236ArgHis: 1.236 ± 0.584
3.708ArgIle: 3.708 ± 1.135
0.618ArgLys: 0.618 ± 0.54
6.18ArgLeu: 6.18 ± 2.026
0.0ArgMet: 0.0 ± 0.0
4.326ArgAsn: 4.326 ± 1.567
3.708ArgPro: 3.708 ± 1.138
0.618ArgGln: 0.618 ± 0.742
9.889ArgArg: 9.889 ± 3.257
6.799ArgSer: 6.799 ± 1.605
3.09ArgThr: 3.09 ± 1.043
4.326ArgVal: 4.326 ± 1.552
1.236ArgTrp: 1.236 ± 0.687
3.09ArgTyr: 3.09 ± 1.72
0.0ArgXaa: 0.0 ± 0.0
Ser
5.562SerAla: 5.562 ± 1.847
1.236SerCys: 1.236 ± 0.761
3.708SerAsp: 3.708 ± 1.147
3.708SerGlu: 3.708 ± 1.332
3.708SerPhe: 3.708 ± 1.479
4.326SerGly: 4.326 ± 2.484
2.472SerHis: 2.472 ± 2.178
7.417SerIle: 7.417 ± 1.978
6.18SerLys: 6.18 ± 1.4
6.799SerLeu: 6.799 ± 3.003
1.854SerMet: 1.854 ± 0.947
4.944SerAsn: 4.944 ± 1.313
3.09SerPro: 3.09 ± 1.451
3.708SerGln: 3.708 ± 1.01
7.417SerArg: 7.417 ± 4.244
9.271SerSer: 9.271 ± 2.83
6.18SerThr: 6.18 ± 1.49
3.09SerVal: 3.09 ± 1.085
0.0SerTrp: 0.0 ± 0.0
3.708SerTyr: 3.708 ± 1.399
0.0SerXaa: 0.0 ± 0.0
Thr
2.472ThrAla: 2.472 ± 1.373
1.236ThrCys: 1.236 ± 0.737
0.618ThrAsp: 0.618 ± 0.492
1.854ThrGlu: 1.854 ± 0.917
3.09ThrPhe: 3.09 ± 0.985
2.472ThrGly: 2.472 ± 1.056
4.326ThrHis: 4.326 ± 1.268
4.326ThrIle: 4.326 ± 1.493
3.09ThrLys: 3.09 ± 0.869
4.326ThrLeu: 4.326 ± 0.849
0.618ThrMet: 0.618 ± 0.483
3.09ThrAsn: 3.09 ± 0.595
6.18ThrPro: 6.18 ± 2.07
2.472ThrGln: 2.472 ± 0.899
4.326ThrArg: 4.326 ± 0.878
6.799ThrSer: 6.799 ± 3.191
4.326ThrThr: 4.326 ± 1.844
2.472ThrVal: 2.472 ± 0.86
1.236ThrTrp: 1.236 ± 0.766
2.472ThrTyr: 2.472 ± 0.739
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
3.09ValAsp: 3.09 ± 1.56
3.708ValGlu: 3.708 ± 1.185
1.854ValPhe: 1.854 ± 0.884
2.472ValGly: 2.472 ± 1.085
0.618ValHis: 0.618 ± 0.742
4.944ValIle: 4.944 ± 1.99
8.035ValLys: 8.035 ± 1.534
4.944ValLeu: 4.944 ± 1.265
3.708ValMet: 3.708 ± 1.191
1.854ValAsn: 1.854 ± 0.767
2.472ValPro: 2.472 ± 0.586
4.326ValGln: 4.326 ± 2.151
4.326ValArg: 4.326 ± 0.818
4.326ValSer: 4.326 ± 2.438
3.09ValThr: 3.09 ± 1.0
0.618ValVal: 0.618 ± 0.54
0.618ValTrp: 0.618 ± 0.54
6.18ValTyr: 6.18 ± 2.435
0.0ValXaa: 0.0 ± 0.0
Trp
3.09TrpAla: 3.09 ± 1.301
0.0TrpCys: 0.0 ± 0.0
0.618TrpAsp: 0.618 ± 0.693
1.236TrpGlu: 1.236 ± 0.766
0.0TrpPhe: 0.0 ± 0.0
1.854TrpGly: 1.854 ± 1.412
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.618TrpMet: 0.618 ± 0.54
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.618TrpGln: 0.618 ± 0.483
1.236TrpArg: 1.236 ± 0.822
1.236TrpSer: 1.236 ± 0.663
0.618TrpThr: 0.618 ± 0.708
0.618TrpVal: 0.618 ± 0.54
0.618TrpTrp: 0.618 ± 0.54
0.618TrpTyr: 0.618 ± 0.483
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.472TyrAla: 2.472 ± 1.194
0.0TyrCys: 0.0 ± 0.0
3.09TyrAsp: 3.09 ± 1.607
1.236TyrGlu: 1.236 ± 0.665
1.236TyrPhe: 1.236 ± 0.616
2.472TyrGly: 2.472 ± 0.961
1.236TyrHis: 1.236 ± 0.967
3.708TyrIle: 3.708 ± 1.08
3.708TyrLys: 3.708 ± 0.995
4.944TyrLeu: 4.944 ± 1.561
1.236TyrMet: 1.236 ± 0.771
1.854TyrAsn: 1.854 ± 0.669
3.09TyrPro: 3.09 ± 1.204
0.0TyrGln: 0.0 ± 0.0
5.562TyrArg: 5.562 ± 2.008
2.472TyrSer: 2.472 ± 0.918
1.236TyrThr: 1.236 ± 0.584
2.472TyrVal: 2.472 ± 1.065
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski