Amino acid dipepetide frequency for Hubei sobemo-like virus 46

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.808AlaAla: 4.808 ± 3.213
1.202AlaCys: 1.202 ± 0.986
4.808AlaAsp: 4.808 ± 0.366
1.202AlaGlu: 1.202 ± 0.803
2.404AlaPhe: 2.404 ± 1.607
3.606AlaGly: 3.606 ± 0.62
0.0AlaHis: 0.0 ± 0.0
2.404AlaIle: 2.404 ± 0.183
1.202AlaLys: 1.202 ± 0.986
8.413AlaLeu: 8.413 ± 3.834
1.202AlaMet: 1.202 ± 1.273
3.606AlaAsn: 3.606 ± 0.62
1.202AlaPro: 1.202 ± 0.986
1.202AlaGln: 1.202 ± 0.986
3.606AlaArg: 3.606 ± 0.62
4.808AlaSer: 4.808 ± 2.155
1.202AlaThr: 1.202 ± 0.803
4.808AlaVal: 4.808 ± 0.366
1.202AlaTrp: 1.202 ± 0.986
7.212AlaTyr: 7.212 ± 2.338
0.0AlaXaa: 0.0 ± 0.0
Cys
2.404CysAla: 2.404 ± 0.183
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.202CysPhe: 1.202 ± 0.986
2.404CysGly: 2.404 ± 1.607
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.202CysLys: 1.202 ± 0.986
3.606CysLeu: 3.606 ± 2.958
0.0CysMet: 0.0 ± 0.0
1.202CysAsn: 1.202 ± 0.803
1.202CysPro: 1.202 ± 0.986
1.202CysGln: 1.202 ± 0.803
2.404CysArg: 2.404 ± 1.972
1.202CysSer: 1.202 ± 0.986
1.202CysThr: 1.202 ± 0.803
1.202CysVal: 1.202 ± 0.986
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.202AspAla: 1.202 ± 0.803
0.0AspCys: 0.0 ± 0.0
2.404AspAsp: 2.404 ± 0.183
2.404AspGlu: 2.404 ± 1.972
2.404AspPhe: 2.404 ± 1.607
6.01AspGly: 6.01 ± 4.016
1.202AspHis: 1.202 ± 0.803
0.0AspIle: 0.0 ± 0.0
3.606AspLys: 3.606 ± 0.62
3.606AspLeu: 3.606 ± 1.169
4.808AspMet: 4.808 ± 2.155
3.606AspAsn: 3.606 ± 2.958
1.202AspPro: 1.202 ± 0.803
1.202AspGln: 1.202 ± 0.986
0.0AspArg: 0.0 ± 0.0
2.404AspSer: 2.404 ± 1.607
6.01AspThr: 6.01 ± 2.227
2.404AspVal: 2.404 ± 1.972
2.404AspTrp: 2.404 ± 0.183
2.404AspTyr: 2.404 ± 1.972
0.0AspXaa: 0.0 ± 0.0
Glu
6.01GluAla: 6.01 ± 0.438
0.0GluCys: 0.0 ± 0.0
3.606GluAsp: 3.606 ± 2.41
3.606GluGlu: 3.606 ± 0.62
4.808GluPhe: 4.808 ± 0.366
2.404GluGly: 2.404 ± 1.972
0.0GluHis: 0.0 ± 0.0
0.0GluIle: 0.0 ± 0.0
4.808GluLys: 4.808 ± 1.424
4.808GluLeu: 4.808 ± 0.366
0.0GluMet: 0.0 ± 0.0
2.404GluAsn: 2.404 ± 1.607
3.606GluPro: 3.606 ± 1.169
2.404GluGln: 2.404 ± 0.183
1.202GluArg: 1.202 ± 0.803
3.606GluSer: 3.606 ± 0.62
3.606GluThr: 3.606 ± 2.41
6.01GluVal: 6.01 ± 0.438
0.0GluTrp: 0.0 ± 0.0
3.606GluTyr: 3.606 ± 2.958
0.0GluXaa: 0.0 ± 0.0
Phe
1.202PheAla: 1.202 ± 0.803
0.0PheCys: 0.0 ± 0.0
1.202PheAsp: 1.202 ± 0.803
4.808PheGlu: 4.808 ± 3.213
1.202PhePhe: 1.202 ± 0.986
3.606PheGly: 3.606 ± 0.62
1.202PheHis: 1.202 ± 0.803
1.202PheIle: 1.202 ± 0.986
3.606PheLys: 3.606 ± 2.41
2.404PheLeu: 2.404 ± 0.183
3.606PheMet: 3.606 ± 2.5
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
1.202PheArg: 1.202 ± 0.803
6.01PheSer: 6.01 ± 0.438
2.404PheThr: 2.404 ± 1.972
1.202PheVal: 1.202 ± 0.986
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.01GlyAla: 6.01 ± 2.227
2.404GlyCys: 2.404 ± 0.183
1.202GlyAsp: 1.202 ± 0.986
3.606GlyGlu: 3.606 ± 2.41
6.01GlyPhe: 6.01 ± 2.227
6.01GlyGly: 6.01 ± 2.227
1.202GlyHis: 1.202 ± 0.986
4.808GlyIle: 4.808 ± 0.366
4.808GlyLys: 4.808 ± 1.424
4.808GlyLeu: 4.808 ± 2.155
1.202GlyMet: 1.202 ± 0.803
0.0GlyAsn: 0.0 ± 0.0
3.606GlyPro: 3.606 ± 0.62
4.808GlyGln: 4.808 ± 0.366
8.413GlyArg: 8.413 ± 0.255
6.01GlySer: 6.01 ± 2.227
1.202GlyThr: 1.202 ± 0.803
4.808GlyVal: 4.808 ± 1.424
2.404GlyTrp: 2.404 ± 1.972
2.404GlyTyr: 2.404 ± 0.183
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.202HisAsp: 1.202 ± 0.803
2.404HisGlu: 2.404 ± 0.183
0.0HisPhe: 0.0 ± 0.0
1.202HisGly: 1.202 ± 0.803
0.0HisHis: 0.0 ± 0.0
3.606HisIle: 3.606 ± 0.62
1.202HisLys: 1.202 ± 0.986
1.202HisLeu: 1.202 ± 0.803
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
1.202HisGln: 1.202 ± 0.803
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
6.01HisVal: 6.01 ± 3.141
0.0HisTrp: 0.0 ± 0.0
1.202HisTyr: 1.202 ± 0.986
0.0HisXaa: 0.0 ± 0.0
Ile
2.404IleAla: 2.404 ± 0.183
0.0IleCys: 0.0 ± 0.0
1.202IleAsp: 1.202 ± 0.803
3.606IleGlu: 3.606 ± 1.169
1.202IlePhe: 1.202 ± 0.986
1.202IleGly: 1.202 ± 0.986
2.404IleHis: 2.404 ± 1.607
0.0IleIle: 0.0 ± 0.0
1.202IleLys: 1.202 ± 0.986
4.808IleLeu: 4.808 ± 1.424
3.606IleMet: 3.606 ± 1.169
0.0IleAsn: 0.0 ± 0.0
2.404IlePro: 2.404 ± 1.972
0.0IleGln: 0.0 ± 0.0
2.404IleArg: 2.404 ± 1.607
4.808IleSer: 4.808 ± 2.155
2.404IleThr: 2.404 ± 1.607
8.413IleVal: 8.413 ± 0.255
2.404IleTrp: 2.404 ± 1.972
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
4.808LysAla: 4.808 ± 0.366
1.202LysCys: 1.202 ± 0.803
0.0LysAsp: 0.0 ± 0.0
1.202LysGlu: 1.202 ± 0.986
2.404LysPhe: 2.404 ± 0.183
2.404LysGly: 2.404 ± 0.183
1.202LysHis: 1.202 ± 0.986
2.404LysIle: 2.404 ± 0.183
2.404LysLys: 2.404 ± 0.183
2.404LysLeu: 2.404 ± 0.183
2.404LysMet: 2.404 ± 1.607
0.0LysAsn: 0.0 ± 0.0
2.404LysPro: 2.404 ± 1.607
3.606LysGln: 3.606 ± 0.62
2.404LysArg: 2.404 ± 1.607
12.019LysSer: 12.019 ± 2.703
1.202LysThr: 1.202 ± 0.803
3.606LysVal: 3.606 ± 0.62
0.0LysTrp: 0.0 ± 0.0
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
2.404LeuAla: 2.404 ± 0.183
2.404LeuCys: 2.404 ± 0.183
7.212LeuAsp: 7.212 ± 2.338
4.808LeuGlu: 4.808 ± 1.424
0.0LeuPhe: 0.0 ± 0.0
9.615LeuGly: 9.615 ± 1.058
1.202LeuHis: 1.202 ± 0.986
3.606LeuIle: 3.606 ± 1.169
2.404LeuLys: 2.404 ± 1.607
2.404LeuLeu: 2.404 ± 1.607
3.606LeuMet: 3.606 ± 0.62
4.808LeuAsn: 4.808 ± 0.366
8.413LeuPro: 8.413 ± 3.324
4.808LeuGln: 4.808 ± 2.155
6.01LeuArg: 6.01 ± 2.227
8.413LeuSer: 8.413 ± 0.255
2.404LeuThr: 2.404 ± 1.607
6.01LeuVal: 6.01 ± 1.352
2.404LeuTrp: 2.404 ± 1.607
3.606LeuTyr: 3.606 ± 2.958
0.0LeuXaa: 0.0 ± 0.0
Met
2.404MetAla: 2.404 ± 0.183
2.404MetCys: 2.404 ± 1.972
1.202MetAsp: 1.202 ± 0.803
3.606MetGlu: 3.606 ± 0.62
1.202MetPhe: 1.202 ± 0.986
2.404MetGly: 2.404 ± 1.607
1.202MetHis: 1.202 ± 0.986
0.0MetIle: 0.0 ± 0.0
3.606MetLys: 3.606 ± 0.62
2.404MetLeu: 2.404 ± 0.183
2.404MetMet: 2.404 ± 0.183
1.202MetAsn: 1.202 ± 0.803
0.0MetPro: 0.0 ± 0.0
1.202MetGln: 1.202 ± 0.986
3.606MetArg: 3.606 ± 0.62
0.0MetSer: 0.0 ± 0.0
1.202MetThr: 1.202 ± 0.803
4.808MetVal: 4.808 ± 1.424
1.202MetTrp: 1.202 ± 0.986
4.808MetTyr: 4.808 ± 2.155
0.0MetXaa: 0.0 ± 0.0
Asn
2.404AsnAla: 2.404 ± 0.183
1.202AsnCys: 1.202 ± 0.986
1.202AsnAsp: 1.202 ± 0.986
3.606AsnGlu: 3.606 ± 1.169
0.0AsnPhe: 0.0 ± 0.0
7.212AsnGly: 7.212 ± 2.338
1.202AsnHis: 1.202 ± 0.986
2.404AsnIle: 2.404 ± 0.183
0.0AsnLys: 0.0 ± 0.0
0.0AsnLeu: 0.0 ± 0.0
2.404AsnMet: 2.404 ± 0.183
1.202AsnAsn: 1.202 ± 0.803
1.202AsnPro: 1.202 ± 0.986
0.0AsnGln: 0.0 ± 0.0
2.404AsnArg: 2.404 ± 1.607
3.606AsnSer: 3.606 ± 0.62
3.606AsnThr: 3.606 ± 0.62
3.606AsnVal: 3.606 ± 2.41
0.0AsnTrp: 0.0 ± 0.0
2.404AsnTyr: 2.404 ± 0.183
0.0AsnXaa: 0.0 ± 0.0
Pro
1.202ProAla: 1.202 ± 0.803
0.0ProCys: 0.0 ± 0.0
2.404ProAsp: 2.404 ± 0.183
2.404ProGlu: 2.404 ± 0.183
0.0ProPhe: 0.0 ± 0.0
4.808ProGly: 4.808 ± 0.366
1.202ProHis: 1.202 ± 0.986
4.808ProIle: 4.808 ± 2.155
2.404ProLys: 2.404 ± 1.607
4.808ProLeu: 4.808 ± 3.944
1.202ProMet: 1.202 ± 0.803
2.404ProAsn: 2.404 ± 0.183
0.0ProPro: 0.0 ± 0.0
1.202ProGln: 1.202 ± 0.803
1.202ProArg: 1.202 ± 0.803
2.404ProSer: 2.404 ± 0.183
2.404ProThr: 2.404 ± 0.183
4.808ProVal: 4.808 ± 2.155
0.0ProTrp: 0.0 ± 0.0
2.404ProTyr: 2.404 ± 0.183
0.0ProXaa: 0.0 ± 0.0
Gln
4.808GlnAla: 4.808 ± 1.424
1.202GlnCys: 1.202 ± 0.986
2.404GlnAsp: 2.404 ± 0.183
2.404GlnGlu: 2.404 ± 0.183
1.202GlnPhe: 1.202 ± 0.986
2.404GlnGly: 2.404 ± 0.183
0.0GlnHis: 0.0 ± 0.0
3.606GlnIle: 3.606 ± 2.958
0.0GlnLys: 0.0 ± 0.0
3.606GlnLeu: 3.606 ± 0.62
1.202GlnMet: 1.202 ± 0.803
2.404GlnAsn: 2.404 ± 1.607
1.202GlnPro: 1.202 ± 0.803
3.606GlnGln: 3.606 ± 0.62
1.202GlnArg: 1.202 ± 0.803
3.606GlnSer: 3.606 ± 0.62
2.404GlnThr: 2.404 ± 1.972
2.404GlnVal: 2.404 ± 0.183
3.606GlnTrp: 3.606 ± 2.958
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.202ArgAla: 1.202 ± 0.803
0.0ArgCys: 0.0 ± 0.0
3.606ArgAsp: 3.606 ± 0.62
3.606ArgGlu: 3.606 ± 0.62
3.606ArgPhe: 3.606 ± 0.62
3.606ArgGly: 3.606 ± 1.169
2.404ArgHis: 2.404 ± 1.607
2.404ArgIle: 2.404 ± 1.607
3.606ArgLys: 3.606 ± 0.62
8.413ArgLeu: 8.413 ± 2.044
3.606ArgMet: 3.606 ± 2.958
1.202ArgAsn: 1.202 ± 0.803
0.0ArgPro: 0.0 ± 0.0
1.202ArgGln: 1.202 ± 0.803
2.404ArgArg: 2.404 ± 1.607
3.606ArgSer: 3.606 ± 0.62
1.202ArgThr: 1.202 ± 0.803
6.01ArgVal: 6.01 ± 2.227
3.606ArgTrp: 3.606 ± 1.169
1.202ArgTyr: 1.202 ± 0.986
0.0ArgXaa: 0.0 ± 0.0
Ser
3.606SerAla: 3.606 ± 1.169
2.404SerCys: 2.404 ± 0.183
2.404SerAsp: 2.404 ± 1.972
4.808SerGlu: 4.808 ± 0.366
2.404SerPhe: 2.404 ± 0.183
4.808SerGly: 4.808 ± 1.424
1.202SerHis: 1.202 ± 0.803
4.808SerIle: 4.808 ± 3.213
4.808SerLys: 4.808 ± 0.366
3.606SerLeu: 3.606 ± 2.41
3.606SerMet: 3.606 ± 1.169
2.404SerAsn: 2.404 ± 0.183
4.808SerPro: 4.808 ± 2.155
6.01SerGln: 6.01 ± 1.352
6.01SerArg: 6.01 ± 1.352
9.615SerSer: 9.615 ± 4.637
4.808SerThr: 4.808 ± 1.424
3.606SerVal: 3.606 ± 2.41
3.606SerTrp: 3.606 ± 2.41
4.808SerTyr: 4.808 ± 0.366
0.0SerXaa: 0.0 ± 0.0
Thr
3.606ThrAla: 3.606 ± 1.169
2.404ThrCys: 2.404 ± 0.183
3.606ThrAsp: 3.606 ± 2.41
1.202ThrGlu: 1.202 ± 0.803
1.202ThrPhe: 1.202 ± 0.803
3.606ThrGly: 3.606 ± 2.41
0.0ThrHis: 0.0 ± 0.0
4.808ThrIle: 4.808 ± 2.155
0.0ThrLys: 0.0 ± 0.0
3.606ThrLeu: 3.606 ± 0.62
0.0ThrMet: 0.0 ± 0.0
4.808ThrAsn: 4.808 ± 0.366
2.404ThrPro: 2.404 ± 1.607
2.404ThrGln: 2.404 ± 1.607
1.202ThrArg: 1.202 ± 0.803
2.404ThrSer: 2.404 ± 1.607
2.404ThrThr: 2.404 ± 0.183
2.404ThrVal: 2.404 ± 1.607
1.202ThrTrp: 1.202 ± 0.803
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.606ValAla: 3.606 ± 2.958
1.202ValCys: 1.202 ± 0.986
3.606ValAsp: 3.606 ± 0.62
3.606ValGlu: 3.606 ± 0.62
2.404ValPhe: 2.404 ± 0.183
8.413ValGly: 8.413 ± 0.255
2.404ValHis: 2.404 ± 0.183
1.202ValIle: 1.202 ± 0.986
6.01ValLys: 6.01 ± 3.141
7.212ValLeu: 7.212 ± 0.548
3.606ValMet: 3.606 ± 2.41
3.606ValAsn: 3.606 ± 1.169
6.01ValPro: 6.01 ± 2.227
3.606ValGln: 3.606 ± 1.169
4.808ValArg: 4.808 ± 3.213
4.808ValSer: 4.808 ± 1.424
2.404ValThr: 2.404 ± 1.607
3.606ValVal: 3.606 ± 0.62
3.606ValTrp: 3.606 ± 0.62
4.808ValTyr: 4.808 ± 1.424
0.0ValXaa: 0.0 ± 0.0
Trp
2.404TrpAla: 2.404 ± 0.183
0.0TrpCys: 0.0 ± 0.0
1.202TrpAsp: 1.202 ± 0.986
0.0TrpGlu: 0.0 ± 0.0
1.202TrpPhe: 1.202 ± 0.803
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
2.404TrpIle: 2.404 ± 1.607
1.202TrpLys: 1.202 ± 0.986
4.808TrpLeu: 4.808 ± 1.424
0.0TrpMet: 0.0 ± 0.0
3.606TrpAsn: 3.606 ± 2.958
1.202TrpPro: 1.202 ± 0.986
1.202TrpGln: 1.202 ± 0.986
2.404TrpArg: 2.404 ± 1.972
2.404TrpSer: 2.404 ± 1.607
1.202TrpThr: 1.202 ± 0.986
1.202TrpVal: 1.202 ± 0.803
0.0TrpTrp: 0.0 ± 0.0
2.404TrpTyr: 2.404 ± 1.972
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.808TyrAla: 4.808 ± 0.366
2.404TyrCys: 2.404 ± 0.183
4.808TyrAsp: 4.808 ± 2.155
3.606TyrGlu: 3.606 ± 1.169
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
1.202TyrHis: 1.202 ± 0.986
0.0TyrIle: 0.0 ± 0.0
0.0TyrLys: 0.0 ± 0.0
9.615TyrLeu: 9.615 ± 6.099
1.202TyrMet: 1.202 ± 0.803
1.202TyrAsn: 1.202 ± 0.986
1.202TyrPro: 1.202 ± 0.986
2.404TyrGln: 2.404 ± 0.183
3.606TyrArg: 3.606 ± 2.958
2.404TyrSer: 2.404 ± 0.183
0.0TyrThr: 0.0 ± 0.0
3.606TyrVal: 3.606 ± 0.62
1.202TyrTrp: 1.202 ± 0.986
2.404TyrTyr: 2.404 ± 1.972
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (833 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski