Amino acid dipepetide frequency for Spider associated circular virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.821AlaAla: 1.821 ± 1.081
1.821AlaCys: 1.821 ± 1.493
3.643AlaAsp: 3.643 ± 0.413
0.0AlaGlu: 0.0 ± 0.0
0.0AlaPhe: 0.0 ± 0.0
7.286AlaGly: 7.286 ± 0.825
3.643AlaHis: 3.643 ± 2.161
7.286AlaIle: 7.286 ± 1.749
3.643AlaLys: 3.643 ± 0.413
5.464AlaLeu: 5.464 ± 1.906
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
1.821AlaPro: 1.821 ± 1.081
3.643AlaGln: 3.643 ± 2.161
1.821AlaArg: 1.821 ± 1.493
1.821AlaSer: 1.821 ± 1.081
5.464AlaThr: 5.464 ± 0.668
3.643AlaVal: 3.643 ± 0.413
0.0AlaTrp: 0.0 ± 0.0
5.464AlaTyr: 5.464 ± 0.668
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.821CysAsp: 1.821 ± 1.081
0.0CysGlu: 0.0 ± 0.0
1.821CysPhe: 1.821 ± 1.081
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
3.643CysIle: 3.643 ± 0.413
1.821CysLys: 1.821 ± 1.081
1.821CysLeu: 1.821 ± 1.081
0.0CysMet: 0.0 ± 0.0
1.821CysAsn: 1.821 ± 1.493
1.821CysPro: 1.821 ± 1.081
1.821CysGln: 1.821 ± 1.081
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.821AspAla: 1.821 ± 1.493
0.0AspCys: 0.0 ± 0.0
9.107AspAsp: 9.107 ± 2.829
5.464AspGlu: 5.464 ± 0.668
1.821AspPhe: 1.821 ± 1.081
3.643AspGly: 3.643 ± 2.161
3.643AspHis: 3.643 ± 2.161
3.643AspIle: 3.643 ± 0.413
1.821AspLys: 1.821 ± 1.081
7.286AspLeu: 7.286 ± 0.825
0.0AspMet: 0.0 ± 0.0
3.643AspAsn: 3.643 ± 0.413
1.821AspPro: 1.821 ± 1.081
0.0AspGln: 0.0 ± 0.0
3.643AspArg: 3.643 ± 2.161
1.821AspSer: 1.821 ± 1.081
1.821AspThr: 1.821 ± 1.493
5.464AspVal: 5.464 ± 0.668
3.643AspTrp: 3.643 ± 0.413
3.643AspTyr: 3.643 ± 0.413
0.0AspXaa: 0.0 ± 0.0
Glu
3.643GluAla: 3.643 ± 0.413
0.0GluCys: 0.0 ± 0.0
1.821GluAsp: 1.821 ± 1.081
1.821GluGlu: 1.821 ± 1.081
1.821GluPhe: 1.821 ± 1.493
1.821GluGly: 1.821 ± 1.081
0.0GluHis: 0.0 ± 0.0
1.821GluIle: 1.821 ± 1.081
1.821GluLys: 1.821 ± 1.493
1.821GluLeu: 1.821 ± 1.081
1.821GluMet: 1.821 ± 0.857
1.821GluAsn: 1.821 ± 1.081
3.643GluPro: 3.643 ± 2.161
1.821GluGln: 1.821 ± 1.081
1.821GluArg: 1.821 ± 1.081
0.0GluSer: 0.0 ± 0.0
1.821GluThr: 1.821 ± 1.081
5.464GluVal: 5.464 ± 0.668
3.643GluTrp: 3.643 ± 2.161
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.821PheAla: 1.821 ± 1.493
0.0PheCys: 0.0 ± 0.0
3.643PheAsp: 3.643 ± 2.161
5.464PheGlu: 5.464 ± 0.668
0.0PhePhe: 0.0 ± 0.0
3.643PheGly: 3.643 ± 0.413
1.821PheHis: 1.821 ± 1.493
1.821PheIle: 1.821 ± 1.081
0.0PheLys: 0.0 ± 0.0
3.643PheLeu: 3.643 ± 0.413
0.0PheMet: 0.0 ± 0.0
3.643PheAsn: 3.643 ± 0.413
3.643PhePro: 3.643 ± 2.986
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
1.821PheSer: 1.821 ± 1.493
9.107PheThr: 9.107 ± 5.403
1.821PheVal: 1.821 ± 1.493
0.0PheTrp: 0.0 ± 0.0
1.821PheTyr: 1.821 ± 1.493
0.0PheXaa: 0.0 ± 0.0
Gly
5.464GlyAla: 5.464 ± 1.906
0.0GlyCys: 0.0 ± 0.0
3.643GlyAsp: 3.643 ± 2.161
3.643GlyGlu: 3.643 ± 2.161
1.821GlyPhe: 1.821 ± 1.493
1.821GlyGly: 1.821 ± 1.493
0.0GlyHis: 0.0 ± 0.0
1.821GlyIle: 1.821 ± 1.081
3.643GlyLys: 3.643 ± 0.413
7.286GlyLeu: 7.286 ± 0.825
0.0GlyMet: 0.0 ± 0.0
1.821GlyAsn: 1.821 ± 1.081
1.821GlyPro: 1.821 ± 1.081
1.821GlyGln: 1.821 ± 1.081
3.643GlyArg: 3.643 ± 0.413
9.107GlySer: 9.107 ± 2.318
10.929GlyThr: 10.929 ± 3.91
1.821GlyVal: 1.821 ± 1.493
0.0GlyTrp: 0.0 ± 0.0
5.464GlyTyr: 5.464 ± 1.906
0.0GlyXaa: 0.0 ± 0.0
His
1.821HisAla: 1.821 ± 1.493
0.0HisCys: 0.0 ± 0.0
1.821HisAsp: 1.821 ± 1.493
0.0HisGlu: 0.0 ± 0.0
3.643HisPhe: 3.643 ± 2.161
1.821HisGly: 1.821 ± 1.081
1.821HisHis: 1.821 ± 1.493
1.821HisIle: 1.821 ± 1.493
1.821HisLys: 1.821 ± 1.081
3.643HisLeu: 3.643 ± 2.161
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.821HisPro: 1.821 ± 1.081
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
3.643HisThr: 3.643 ± 0.413
7.286HisVal: 7.286 ± 1.749
3.643HisTrp: 3.643 ± 2.161
1.821HisTyr: 1.821 ± 1.081
0.0HisXaa: 0.0 ± 0.0
Ile
1.821IleAla: 1.821 ± 1.081
0.0IleCys: 0.0 ± 0.0
5.464IleAsp: 5.464 ± 0.668
1.821IleGlu: 1.821 ± 1.081
9.107IlePhe: 9.107 ± 5.403
1.821IleGly: 1.821 ± 1.081
3.643IleHis: 3.643 ± 2.161
3.643IleIle: 3.643 ± 2.161
5.464IleLys: 5.464 ± 1.906
0.0IleLeu: 0.0 ± 0.0
0.0IleMet: 0.0 ± 0.999
7.286IleAsn: 7.286 ± 0.825
1.821IlePro: 1.821 ± 1.081
1.821IleGln: 1.821 ± 1.081
3.643IleArg: 3.643 ± 0.413
1.821IleSer: 1.821 ± 1.081
3.643IleThr: 3.643 ± 2.986
1.821IleVal: 1.821 ± 1.493
0.0IleTrp: 0.0 ± 0.0
3.643IleTyr: 3.643 ± 2.161
0.0IleXaa: 0.0 ± 0.0
Lys
7.286LysAla: 7.286 ± 1.749
0.0LysCys: 0.0 ± 0.0
1.821LysAsp: 1.821 ± 1.081
1.821LysGlu: 1.821 ± 1.493
3.643LysPhe: 3.643 ± 2.986
3.643LysGly: 3.643 ± 0.413
1.821LysHis: 1.821 ± 1.081
1.821LysIle: 1.821 ± 1.081
1.821LysLys: 1.821 ± 1.493
1.821LysLeu: 1.821 ± 1.493
0.0LysMet: 0.0 ± 0.0
5.464LysAsn: 5.464 ± 0.668
5.464LysPro: 5.464 ± 1.906
1.821LysGln: 1.821 ± 1.081
14.572LysArg: 14.572 ± 6.798
5.464LysSer: 5.464 ± 4.48
3.643LysThr: 3.643 ± 0.413
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
7.286LysTyr: 7.286 ± 5.973
0.0LysXaa: 0.0 ± 0.0
Leu
3.643LeuAla: 3.643 ± 0.413
3.643LeuCys: 3.643 ± 2.161
1.821LeuAsp: 1.821 ± 1.493
9.107LeuGlu: 9.107 ± 5.403
1.821LeuPhe: 1.821 ± 1.081
5.464LeuGly: 5.464 ± 1.906
5.464LeuHis: 5.464 ± 0.668
1.821LeuIle: 1.821 ± 1.493
7.286LeuLys: 7.286 ± 0.825
5.464LeuLeu: 5.464 ± 1.906
1.821LeuMet: 1.821 ± 1.493
1.821LeuAsn: 1.821 ± 1.493
5.464LeuPro: 5.464 ± 0.668
3.643LeuGln: 3.643 ± 0.413
3.643LeuArg: 3.643 ± 0.413
5.464LeuSer: 5.464 ± 0.668
5.464LeuThr: 5.464 ± 1.906
7.286LeuVal: 7.286 ± 0.825
0.0LeuTrp: 0.0 ± 0.0
0.0LeuTyr: 0.0 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.821MetGly: 1.821 ± 1.493
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.821MetPro: 1.821 ± 1.081
1.821MetGln: 1.821 ± 1.493
0.0MetArg: 0.0 ± 0.0
1.821MetSer: 1.821 ± 1.081
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.821AsnAla: 1.821 ± 1.081
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.821AsnGlu: 1.821 ± 1.081
0.0AsnPhe: 0.0 ± 0.0
3.643AsnGly: 3.643 ± 2.161
1.821AsnHis: 1.821 ± 1.493
5.464AsnIle: 5.464 ± 1.906
3.643AsnLys: 3.643 ± 2.986
7.286AsnLeu: 7.286 ± 1.749
0.0AsnMet: 0.0 ± 0.0
1.821AsnAsn: 1.821 ± 1.081
3.643AsnPro: 3.643 ± 2.161
1.821AsnGln: 1.821 ± 1.081
1.821AsnArg: 1.821 ± 1.493
5.464AsnSer: 5.464 ± 1.906
3.643AsnThr: 3.643 ± 2.161
1.821AsnVal: 1.821 ± 1.081
1.821AsnTrp: 1.821 ± 1.081
1.821AsnTyr: 1.821 ± 1.493
0.0AsnXaa: 0.0 ± 0.0
Pro
9.107ProAla: 9.107 ± 0.256
0.0ProCys: 0.0 ± 0.0
3.643ProAsp: 3.643 ± 0.413
3.643ProGlu: 3.643 ± 0.413
3.643ProPhe: 3.643 ± 0.413
0.0ProGly: 0.0 ± 0.0
0.0ProHis: 0.0 ± 0.0
3.643ProIle: 3.643 ± 0.413
5.464ProLys: 5.464 ± 0.668
5.464ProLeu: 5.464 ± 1.906
0.0ProMet: 0.0 ± 0.0
1.821ProAsn: 1.821 ± 1.081
0.0ProPro: 0.0 ± 0.0
5.464ProGln: 5.464 ± 0.668
3.643ProArg: 3.643 ± 2.161
1.821ProSer: 1.821 ± 1.081
3.643ProThr: 3.643 ± 0.413
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.821ProTyr: 1.821 ± 1.493
0.0ProXaa: 0.0 ± 0.0
Gln
1.821GlnAla: 1.821 ± 1.081
0.0GlnCys: 0.0 ± 0.0
1.821GlnAsp: 1.821 ± 1.081
0.0GlnGlu: 0.0 ± 0.0
1.821GlnPhe: 1.821 ± 1.081
5.464GlnGly: 5.464 ± 3.242
3.643GlnHis: 3.643 ± 0.413
0.0GlnIle: 0.0 ± 0.0
5.464GlnLys: 5.464 ± 1.906
1.821GlnLeu: 1.821 ± 1.081
1.821GlnMet: 1.821 ± 1.081
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
1.821GlnGln: 1.821 ± 1.081
1.821GlnArg: 1.821 ± 1.493
1.821GlnSer: 1.821 ± 1.493
3.643GlnThr: 3.643 ± 0.413
3.643GlnVal: 3.643 ± 0.413
0.0GlnTrp: 0.0 ± 0.0
1.821GlnTyr: 1.821 ± 1.081
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
1.821ArgAsp: 1.821 ± 1.081
0.0ArgGlu: 0.0 ± 0.0
5.464ArgPhe: 5.464 ± 4.48
7.286ArgGly: 7.286 ± 0.825
1.821ArgHis: 1.821 ± 1.081
3.643ArgIle: 3.643 ± 2.161
7.286ArgLys: 7.286 ± 5.973
9.107ArgLeu: 9.107 ± 0.256
0.0ArgMet: 0.0 ± 0.0
3.643ArgAsn: 3.643 ± 2.161
3.643ArgPro: 3.643 ± 0.413
3.643ArgGln: 3.643 ± 0.413
10.929ArgArg: 10.929 ± 1.238
1.821ArgSer: 1.821 ± 1.081
3.643ArgThr: 3.643 ± 0.413
3.643ArgVal: 3.643 ± 0.413
1.821ArgTrp: 1.821 ± 1.081
3.643ArgTyr: 3.643 ± 0.413
0.0ArgXaa: 0.0 ± 0.0
Ser
7.286SerAla: 7.286 ± 4.322
1.821SerCys: 1.821 ± 1.081
3.643SerAsp: 3.643 ± 2.986
0.0SerGlu: 0.0 ± 0.0
3.643SerPhe: 3.643 ± 0.413
9.107SerGly: 9.107 ± 0.256
3.643SerHis: 3.643 ± 2.161
3.643SerIle: 3.643 ± 0.413
1.821SerLys: 1.821 ± 1.493
1.821SerLeu: 1.821 ± 1.081
0.0SerMet: 0.0 ± 0.0
1.821SerAsn: 1.821 ± 1.493
3.643SerPro: 3.643 ± 2.986
0.0SerGln: 0.0 ± 0.0
3.643SerArg: 3.643 ± 0.413
1.821SerSer: 1.821 ± 1.493
5.464SerThr: 5.464 ± 4.48
1.821SerVal: 1.821 ± 1.493
0.0SerTrp: 0.0 ± 0.0
3.643SerTyr: 3.643 ± 0.413
0.0SerXaa: 0.0 ± 0.0
Thr
1.821ThrAla: 1.821 ± 1.081
1.821ThrCys: 1.821 ± 1.493
5.464ThrAsp: 5.464 ± 3.242
3.643ThrGlu: 3.643 ± 2.161
1.821ThrPhe: 1.821 ± 1.493
1.821ThrGly: 1.821 ± 1.493
0.0ThrHis: 0.0 ± 0.0
7.286ThrIle: 7.286 ± 1.749
9.107ThrLys: 9.107 ± 2.318
5.464ThrLeu: 5.464 ± 1.906
0.0ThrMet: 0.0 ± 0.0
5.464ThrAsn: 5.464 ± 0.668
1.821ThrPro: 1.821 ± 1.081
0.0ThrGln: 0.0 ± 0.0
9.107ThrArg: 9.107 ± 2.829
5.464ThrSer: 5.464 ± 1.906
3.643ThrThr: 3.643 ± 2.986
3.643ThrVal: 3.643 ± 0.413
3.643ThrTrp: 3.643 ± 0.413
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.464ValAla: 5.464 ± 0.668
0.0ValCys: 0.0 ± 0.0
3.643ValAsp: 3.643 ± 2.986
0.0ValGlu: 0.0 ± 0.0
0.0ValPhe: 0.0 ± 0.0
0.0ValGly: 0.0 ± 0.0
1.821ValHis: 1.821 ± 1.081
3.643ValIle: 3.643 ± 2.161
5.464ValLys: 5.464 ± 1.906
3.643ValLeu: 3.643 ± 2.161
0.0ValMet: 0.0 ± 0.0
3.643ValAsn: 3.643 ± 0.413
7.286ValPro: 7.286 ± 5.973
1.821ValGln: 1.821 ± 1.493
7.286ValArg: 7.286 ± 1.749
5.464ValSer: 5.464 ± 0.668
1.821ValThr: 1.821 ± 1.081
3.643ValVal: 3.643 ± 0.413
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
3.643TrpCys: 3.643 ± 2.161
1.821TrpAsp: 1.821 ± 1.081
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.821TrpGly: 1.821 ± 1.081
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.821TrpLys: 1.821 ± 1.493
1.821TrpLeu: 1.821 ± 1.081
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
1.821TrpPro: 1.821 ± 1.081
1.821TrpGln: 1.821 ± 1.081
0.0TrpArg: 0.0 ± 0.0
3.643TrpSer: 3.643 ± 0.413
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.821TyrAla: 1.821 ± 1.493
3.643TyrCys: 3.643 ± 2.161
7.286TyrAsp: 7.286 ± 1.749
0.0TyrGlu: 0.0 ± 0.0
1.821TyrPhe: 1.821 ± 1.493
3.643TyrGly: 3.643 ± 2.986
1.821TyrHis: 1.821 ± 1.493
3.643TyrIle: 3.643 ± 2.161
0.0TyrLys: 0.0 ± 0.0
5.464TyrLeu: 5.464 ± 4.48
0.0TyrMet: 0.0 ± 0.0
3.643TyrAsn: 3.643 ± 2.161
0.0TyrPro: 0.0 ± 0.0
3.643TyrGln: 3.643 ± 2.986
1.821TyrArg: 1.821 ± 1.493
1.821TyrSer: 1.821 ± 1.493
0.0TyrThr: 0.0 ± 0.0
1.821TyrVal: 1.821 ± 1.081
0.0TyrTrp: 0.0 ± 0.0
5.464TyrTyr: 5.464 ± 4.48
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (550 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski