Amino acid dipepetide frequency for Romboutsia maritimum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.052AlaAla: 3.052 ± 0.084	0.691AlaCys: 0.691 ± 0.034	2.275AlaAsp: 2.275 ± 0.065	2.401AlaGlu: 2.401 ± 0.065	2.129AlaPhe: 2.129 ± 0.059	3.307AlaGly: 3.307 ± 0.085	0.801AlaHis: 0.801 ± 0.032	5.678AlaIle: 5.678 ± 0.102	4.705AlaLys: 4.705 ± 0.082	5.132AlaLeu: 5.132 ± 0.108	1.58AlaMet: 1.58 ± 0.05	2.719AlaAsn: 2.719 ± 0.063	1.28AlaPro: 1.28 ± 0.045	1.564AlaGln: 1.564 ± 0.046	1.69AlaArg: 1.69 ± 0.05	3.293AlaSer: 3.293 ± 0.08	2.904AlaThr: 2.904 ± 0.06	3.297AlaVal: 3.297 ± 0.081	0.277AlaTrp: 0.277 ± 0.02	1.921AlaTyr: 1.921 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.652CysAla: 0.652 ± 0.03	0.204CysCys: 0.204 ± 0.022	0.755CysAsp: 0.755 ± 0.034	0.815CysGlu: 0.815 ± 0.031	0.436CysPhe: 0.436 ± 0.023	0.998CysGly: 0.998 ± 0.038	0.183CysHis: 0.183 ± 0.017	1.242CysIle: 1.242 ± 0.04	1.101CysLys: 1.101 ± 0.039	0.936CysLeu: 0.936 ± 0.034	0.367CysMet: 0.367 ± 0.022	0.779CysAsn: 0.779 ± 0.039	0.508CysPro: 0.508 ± 0.034	0.253CysGln: 0.253 ± 0.018	0.33CysArg: 0.33 ± 0.022	0.783CysSer: 0.783 ± 0.032	0.557CysThr: 0.557 ± 0.027	0.661CysVal: 0.661 ± 0.032	0.055CysTrp: 0.055 ± 0.008	0.404CysTyr: 0.404 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	2.608AspAla: 2.608 ± 0.066	0.63AspCys: 0.63 ± 0.031	2.902AspAsp: 2.902 ± 0.07	4.833AspGlu: 4.833 ± 0.093	2.649AspPhe: 2.649 ± 0.055	2.985AspGly: 2.985 ± 0.071	0.538AspHis: 0.538 ± 0.027	7.115AspIle: 7.115 ± 0.106	6.289AspLys: 6.289 ± 0.094	5.252AspLeu: 5.252 ± 0.096	1.62AspMet: 1.62 ± 0.046	3.523AspAsn: 3.523 ± 0.078	1.132AspPro: 1.132 ± 0.042	0.869AspGln: 0.869 ± 0.036	1.779AspArg: 1.779 ± 0.051	3.105AspSer: 3.105 ± 0.061	2.613AspThr: 2.613 ± 0.062	3.663AspVal: 3.663 ± 0.073	0.314AspTrp: 0.314 ± 0.021	2.712AspTyr: 2.712 ± 0.064	0.0AspXaa: 0.0 ± 0.0
Glu	3.432GluAla: 3.432 ± 0.071	0.695GluCys: 0.695 ± 0.033	4.488GluAsp: 4.488 ± 0.09	6.564GluGlu: 6.564 ± 0.119	3.108GluPhe: 3.108 ± 0.067	3.82GluGly: 3.82 ± 0.079	0.924GluHis: 0.924 ± 0.034	7.478GluIle: 7.478 ± 0.123	7.489GluLys: 7.489 ± 0.11	6.635GluLeu: 6.635 ± 0.106	1.818GluMet: 1.818 ± 0.048	5.834GluAsn: 5.834 ± 0.095	1.206GluPro: 1.206 ± 0.045	1.779GluGln: 1.779 ± 0.052	2.121GluArg: 2.121 ± 0.059	3.753GluSer: 3.753 ± 0.068	2.786GluThr: 2.786 ± 0.056	4.985GluVal: 4.985 ± 0.089	0.329GluTrp: 0.329 ± 0.022	3.145GluTyr: 3.145 ± 0.072	0.0GluXaa: 0.0 ± 0.0
Phe	2.109PheAla: 2.109 ± 0.055	0.454PheCys: 0.454 ± 0.026	2.486PheAsp: 2.486 ± 0.049	2.864PheGlu: 2.864 ± 0.064	1.857PhePhe: 1.857 ± 0.06	2.618PheGly: 2.618 ± 0.06	0.419PheHis: 0.419 ± 0.023	4.945PheIle: 4.945 ± 0.1	4.028PheLys: 4.028 ± 0.082	3.827PheLeu: 3.827 ± 0.087	1.134PheMet: 1.134 ± 0.039	3.001PheAsn: 3.001 ± 0.062	0.978PhePro: 0.978 ± 0.038	0.701PheGln: 0.701 ± 0.032	1.125PheArg: 1.125 ± 0.035	2.823PheSer: 2.823 ± 0.065	2.301PheThr: 2.301 ± 0.062	2.488PheVal: 2.488 ± 0.061	0.26PheTrp: 0.26 ± 0.018	1.693PheTyr: 1.693 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	3.588GlyAla: 3.588 ± 0.079	1.022GlyCys: 1.022 ± 0.041	2.977GlyAsp: 2.977 ± 0.065	3.814GlyGlu: 3.814 ± 0.071	2.834GlyPhe: 2.834 ± 0.058	3.992GlyGly: 3.992 ± 0.097	0.973GlyHis: 0.973 ± 0.033	6.831GlyIle: 6.831 ± 0.1	5.208GlyLys: 5.208 ± 0.091	5.239GlyLeu: 5.239 ± 0.092	1.708GlyMet: 1.708 ± 0.049	3.192GlyAsn: 3.192 ± 0.064	1.188GlyPro: 1.188 ± 0.044	1.425GlyGln: 1.425 ± 0.037	1.901GlyArg: 1.901 ± 0.054	3.688GlySer: 3.688 ± 0.074	3.248GlyThr: 3.248 ± 0.077	4.418GlyVal: 4.418 ± 0.088	0.495GlyTrp: 0.495 ± 0.033	3.015GlyTyr: 3.015 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	0.623HisAla: 0.623 ± 0.03	0.163HisCys: 0.163 ± 0.015	0.757HisAsp: 0.757 ± 0.032	0.846HisGlu: 0.846 ± 0.036	0.553HisPhe: 0.553 ± 0.027	0.882HisGly: 0.882 ± 0.038	0.24HisHis: 0.24 ± 0.019	1.44HisIle: 1.44 ± 0.042	1.082HisLys: 1.082 ± 0.04	1.127HisLeu: 1.127 ± 0.031	0.337HisMet: 0.337 ± 0.019	0.779HisAsn: 0.779 ± 0.031	0.566HisPro: 0.566 ± 0.028	0.342HisGln: 0.342 ± 0.019	0.406HisArg: 0.406 ± 0.026	0.809HisSer: 0.809 ± 0.031	0.657HisThr: 0.657 ± 0.032	0.722HisVal: 0.722 ± 0.032	0.065HisTrp: 0.065 ± 0.009	0.513HisTyr: 0.513 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.628IleAla: 5.628 ± 0.099	1.398IleCys: 1.398 ± 0.045	6.802IleAsp: 6.802 ± 0.105	7.569IleGlu: 7.569 ± 0.106	4.303IlePhe: 4.303 ± 0.085	6.624IleGly: 6.624 ± 0.102	1.205IleHis: 1.205 ± 0.04	10.368IleIle: 10.368 ± 0.162	9.925IleLys: 9.925 ± 0.132	10.072IleLeu: 10.072 ± 0.139	2.506IleMet: 2.506 ± 0.058	7.404IleAsn: 7.404 ± 0.127	3.255IlePro: 3.255 ± 0.065	2.454IleGln: 2.454 ± 0.057	2.852IleArg: 2.852 ± 0.055	7.72IleSer: 7.72 ± 0.102	4.935IleThr: 4.935 ± 0.08	6.574IleVal: 6.574 ± 0.099	0.472IleTrp: 0.472 ± 0.025	4.025IleTyr: 4.025 ± 0.086	0.0IleXaa: 0.0 ± 0.0
Lys	4.291LysAla: 4.291 ± 0.08	0.963LysCys: 0.963 ± 0.038	6.259LysAsp: 6.259 ± 0.106	9.221LysGlu: 9.221 ± 0.13	3.706LysPhe: 3.706 ± 0.075	4.888LysGly: 4.888 ± 0.086	1.174LysHis: 1.174 ± 0.04	9.371LysIle: 9.371 ± 0.138	9.063LysLys: 9.063 ± 0.125	8.203LysLeu: 8.203 ± 0.113	2.637LysMet: 2.637 ± 0.061	7.661LysAsn: 7.661 ± 0.134	2.079LysPro: 2.079 ± 0.057	2.611LysGln: 2.611 ± 0.061	2.75LysArg: 2.75 ± 0.066	5.993LysSer: 5.993 ± 0.099	4.194LysThr: 4.194 ± 0.076	6.073LysVal: 6.073 ± 0.093	0.524LysTrp: 0.524 ± 0.032	4.557LysTyr: 4.557 ± 0.072	0.0LysXaa: 0.0 ± 0.0
Leu	4.902LeuAla: 4.902 ± 0.08	1.017LeuCys: 1.017 ± 0.04	5.82LeuAsp: 5.82 ± 0.087	6.506LeuGlu: 6.506 ± 0.107	3.761LeuPhe: 3.761 ± 0.087	6.16LeuGly: 6.16 ± 0.104	0.998LeuHis: 0.998 ± 0.039	8.491LeuIle: 8.491 ± 0.124	8.709LeuLys: 8.709 ± 0.114	7.607LeuLeu: 7.607 ± 0.12	2.18LeuMet: 2.18 ± 0.053	6.47LeuAsn: 6.47 ± 0.101	2.513LeuPro: 2.513 ± 0.061	2.053LeuGln: 2.053 ± 0.049	2.909LeuArg: 2.909 ± 0.063	6.754LeuSer: 6.754 ± 0.093	4.259LeuThr: 4.259 ± 0.089	5.912LeuVal: 5.912 ± 0.108	0.445LeuTrp: 0.445 ± 0.024	3.151LeuTyr: 3.151 ± 0.076	0.0LeuXaa: 0.0 ± 0.0
Met	1.655MetAla: 1.655 ± 0.053	0.301MetCys: 0.301 ± 0.02	1.484MetAsp: 1.484 ± 0.039	1.638MetGlu: 1.638 ± 0.046	1.053MetPhe: 1.053 ± 0.04	1.733MetGly: 1.733 ± 0.045	0.345MetHis: 0.345 ± 0.022	2.603MetIle: 2.603 ± 0.06	2.605MetLys: 2.605 ± 0.058	2.232MetLeu: 2.232 ± 0.056	0.734MetMet: 0.734 ± 0.033	1.727MetAsn: 1.727 ± 0.051	0.846MetPro: 0.846 ± 0.032	0.693MetGln: 0.693 ± 0.029	0.81MetArg: 0.81 ± 0.034	1.941MetSer: 1.941 ± 0.051	1.25MetThr: 1.25 ± 0.04	1.517MetVal: 1.517 ± 0.044	0.132MetTrp: 0.132 ± 0.013	1.026MetTyr: 1.026 ± 0.033	0.0MetXaa: 0.0 ± 0.0
Asn	2.738AsnAla: 2.738 ± 0.062	0.79AsnCys: 0.79 ± 0.03	3.299AsnAsp: 3.299 ± 0.071	4.864AsnGlu: 4.864 ± 0.083	2.591AsnPhe: 2.591 ± 0.059	3.281AsnGly: 3.281 ± 0.076	0.834AsnHis: 0.834 ± 0.032	8.313AsnIle: 8.313 ± 0.159	7.643AsnLys: 7.643 ± 0.112	6.709AsnLeu: 6.709 ± 0.114	1.807AsnMet: 1.807 ± 0.053	5.009AsnAsn: 5.009 ± 0.122	2.243AsnPro: 2.243 ± 0.054	1.779AsnGln: 1.779 ± 0.056	1.81AsnArg: 1.81 ± 0.042	4.152AsnSer: 4.152 ± 0.099	3.202AsnThr: 3.202 ± 0.074	3.659AsnVal: 3.659 ± 0.064	0.39AsnTrp: 0.39 ± 0.024	2.843AsnTyr: 2.843 ± 0.07	0.0AsnXaa: 0.0 ± 0.0
Pro	1.201ProAla: 1.201 ± 0.05	0.325ProCys: 0.325 ± 0.019	1.282ProAsp: 1.282 ± 0.044	1.817ProGlu: 1.817 ± 0.053	1.292ProPhe: 1.292 ± 0.041	1.601ProGly: 1.601 ± 0.044	0.441ProHis: 0.441 ± 0.023	2.865ProIle: 2.865 ± 0.065	2.302ProLys: 2.302 ± 0.055	2.217ProLeu: 2.217 ± 0.059	0.668ProMet: 0.668 ± 0.03	1.588ProAsn: 1.588 ± 0.054	0.542ProPro: 0.542 ± 0.025	0.784ProGln: 0.784 ± 0.033	0.747ProArg: 0.747 ± 0.029	1.722ProSer: 1.722 ± 0.05	1.481ProThr: 1.481 ± 0.046	1.753ProVal: 1.753 ± 0.05	0.198ProTrp: 0.198 ± 0.017	1.107ProTyr: 1.107 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	1.388GlnAla: 1.388 ± 0.046	0.238GlnCys: 0.238 ± 0.018	1.423GlnAsp: 1.423 ± 0.041	1.846GlnGlu: 1.846 ± 0.053	0.878GlnPhe: 0.878 ± 0.037	1.535GlnGly: 1.535 ± 0.048	0.324GlnHis: 0.324 ± 0.02	2.432GlnIle: 2.432 ± 0.063	2.191GlnLys: 2.191 ± 0.049	2.098GlnLeu: 2.098 ± 0.052	0.72GlnMet: 0.72 ± 0.03	1.672GlnAsn: 1.672 ± 0.053	0.608GlnPro: 0.608 ± 0.031	0.699GlnGln: 0.699 ± 0.035	0.936GlnArg: 0.936 ± 0.039	1.495GlnSer: 1.495 ± 0.042	1.161GlnThr: 1.161 ± 0.042	1.603GlnVal: 1.603 ± 0.05	0.157GlnTrp: 0.157 ± 0.016	1.028GlnTyr: 1.028 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	1.58ArgAla: 1.58 ± 0.046	0.382ArgCys: 0.382 ± 0.019	1.727ArgAsp: 1.727 ± 0.048	2.556ArgGlu: 2.556 ± 0.056	1.201ArgPhe: 1.201 ± 0.037	1.797ArgGly: 1.797 ± 0.055	0.434ArgHis: 0.434 ± 0.023	2.863ArgIle: 2.863 ± 0.062	2.748ArgLys: 2.748 ± 0.06	2.628ArgLeu: 2.628 ± 0.057	0.818ArgMet: 0.818 ± 0.03	1.909ArgAsn: 1.909 ± 0.059	0.81ArgPro: 0.81 ± 0.037	0.898ArgGln: 0.898 ± 0.035	1.239ArgArg: 1.239 ± 0.044	1.372ArgSer: 1.372 ± 0.045	1.417ArgThr: 1.417 ± 0.053	2.154ArgVal: 2.154 ± 0.062	0.188ArgTrp: 0.188 ± 0.014	1.423ArgTyr: 1.423 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	2.951SerAla: 2.951 ± 0.058	0.721SerCys: 0.721 ± 0.032	3.161SerAsp: 3.161 ± 0.065	3.84SerGlu: 3.84 ± 0.075	2.879SerPhe: 2.879 ± 0.074	3.962SerGly: 3.962 ± 0.08	0.903SerHis: 0.903 ± 0.034	7.459SerIle: 7.459 ± 0.097	6.67SerLys: 6.67 ± 0.112	6.038SerLeu: 6.038 ± 0.09	1.754SerMet: 1.754 ± 0.045	4.344SerAsn: 4.344 ± 0.091	1.494SerPro: 1.494 ± 0.05	1.823SerGln: 1.823 ± 0.051	2.029SerArg: 2.029 ± 0.055	4.377SerSer: 4.377 ± 0.095	3.316SerThr: 3.316 ± 0.064	3.939SerVal: 3.939 ± 0.068	0.347SerTrp: 0.347 ± 0.023	2.602SerTyr: 2.602 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	2.519ThrAla: 2.519 ± 0.065	0.558ThrCys: 0.558 ± 0.029	2.452ThrAsp: 2.452 ± 0.054	2.56ThrGlu: 2.56 ± 0.062	2.029ThrPhe: 2.029 ± 0.053	3.377ThrGly: 3.377 ± 0.07	0.76ThrHis: 0.76 ± 0.03	5.238ThrIle: 5.238 ± 0.076	4.211ThrLys: 4.211 ± 0.068	4.637ThrLeu: 4.637 ± 0.08	1.198ThrMet: 1.198 ± 0.04	3.039ThrAsn: 3.039 ± 0.075	1.65ThrPro: 1.65 ± 0.048	1.368ThrGln: 1.368 ± 0.043	1.438ThrArg: 1.438 ± 0.042	3.348ThrSer: 3.348 ± 0.069	2.672ThrThr: 2.672 ± 0.064	3.128ThrVal: 3.128 ± 0.066	0.303ThrTrp: 0.303 ± 0.019	1.998ThrTyr: 1.998 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	3.725ValAla: 3.725 ± 0.083	0.89ValCys: 0.89 ± 0.032	4.004ValAsp: 4.004 ± 0.073	4.489ValGlu: 4.489 ± 0.077	2.745ValPhe: 2.745 ± 0.064	4.397ValGly: 4.397 ± 0.092	0.783ValHis: 0.783 ± 0.03	6.191ValIle: 6.191 ± 0.087	5.466ValLys: 5.466 ± 0.091	5.823ValLeu: 5.823 ± 0.086	1.532ValMet: 1.532 ± 0.045	3.911ValAsn: 3.911 ± 0.069	1.746ValPro: 1.746 ± 0.047	1.337ValGln: 1.337 ± 0.044	1.838ValArg: 1.838 ± 0.054	4.419ValSer: 4.419 ± 0.08	3.103ValThr: 3.103 ± 0.069	4.792ValVal: 4.792 ± 0.096	0.34ValTrp: 0.34 ± 0.021	2.428ValTyr: 2.428 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.301TrpAla: 0.301 ± 0.019	0.075TrpCys: 0.075 ± 0.009	0.334TrpAsp: 0.334 ± 0.02	0.334TrpGlu: 0.334 ± 0.019	0.245TrpPhe: 0.245 ± 0.019	0.379TrpGly: 0.379 ± 0.02	0.074TrpHis: 0.074 ± 0.01	0.614TrpIle: 0.614 ± 0.033	0.424TrpLys: 0.424 ± 0.026	0.478TrpLeu: 0.478 ± 0.026	0.186TrpMet: 0.186 ± 0.013	0.374TrpAsn: 0.374 ± 0.023	0.114TrpPro: 0.114 ± 0.011	0.142TrpGln: 0.142 ± 0.015	0.153TrpArg: 0.153 ± 0.016	0.33TrpSer: 0.33 ± 0.023	0.297TrpThr: 0.297 ± 0.022	0.357TrpVal: 0.357 ± 0.024	0.075TrpTrp: 0.075 ± 0.01	0.293TrpTyr: 0.293 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.754TyrAla: 1.754 ± 0.048	0.5TyrCys: 0.5 ± 0.024	2.445TyrAsp: 2.445 ± 0.049	3.012TyrGlu: 3.012 ± 0.063	1.862TyrPhe: 1.862 ± 0.055	2.42TyrGly: 2.42 ± 0.054	0.558TyrHis: 0.558 ± 0.024	4.552TyrIle: 4.552 ± 0.094	4.359TyrLys: 4.359 ± 0.09	3.726TyrLeu: 3.726 ± 0.076	1.021TyrMet: 1.021 ± 0.037	3.026TyrAsn: 3.026 ± 0.071	1.175TyrPro: 1.175 ± 0.041	0.855TyrGln: 0.855 ± 0.03	1.28TyrArg: 1.28 ± 0.039	2.733TyrSer: 2.733 ± 0.063	2.131TyrThr: 2.131 ± 0.055	2.264TyrVal: 2.264 ± 0.049	0.212TyrTrp: 0.212 ± 0.017	1.749TyrTyr: 1.749 ± 0.06	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2679 proteins (797421 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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