Amino acid dipepetide frequency for Hubei diptera virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.449AlaAla: 2.449 ± 0.553
0.0AlaCys: 0.0 ± 0.0
1.633AlaAsp: 1.633 ± 0.816
1.633AlaGlu: 1.633 ± 1.22
0.816AlaPhe: 0.816 ± 0.663
4.898AlaGly: 4.898 ± 3.66
0.816AlaHis: 0.816 ± 0.731
2.449AlaIle: 2.449 ± 0.553
2.449AlaLys: 2.449 ± 0.553
4.082AlaLeu: 4.082 ± 1.197
0.0AlaMet: 0.0 ± 0.561
4.082AlaAsn: 4.082 ± 0.746
4.082AlaPro: 4.082 ± 1.661
0.816AlaGln: 0.816 ± 0.663
0.816AlaArg: 0.816 ± 0.663
4.898AlaSer: 4.898 ± 2.206
4.082AlaThr: 4.082 ± 1.091
6.531AlaVal: 6.531 ± 1.367
0.816AlaTrp: 0.816 ± 0.663
0.816AlaTyr: 0.816 ± 0.663
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.816CysAsp: 0.816 ± 0.731
1.633CysGlu: 1.633 ± 1.327
1.633CysPhe: 1.633 ± 1.327
2.449CysGly: 2.449 ± 0.987
0.0CysHis: 0.0 ± 0.0
0.816CysIle: 0.816 ± 0.61
0.816CysLys: 0.816 ± 0.663
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.816CysAsn: 0.816 ± 0.731
2.449CysPro: 2.449 ± 1.386
1.633CysGln: 1.633 ± 0.794
0.816CysArg: 0.816 ± 0.663
0.816CysSer: 0.816 ± 0.731
0.816CysThr: 0.816 ± 0.61
2.449CysVal: 2.449 ± 0.987
0.816CysTrp: 0.816 ± 0.61
0.816CysTyr: 0.816 ± 0.61
0.0CysXaa: 0.0 ± 0.0
Asp
3.265AspAla: 3.265 ± 1.432
0.816AspCys: 0.816 ± 0.663
1.633AspAsp: 1.633 ± 0.857
2.449AspGlu: 2.449 ± 1.83
2.449AspPhe: 2.449 ± 1.411
3.265AspGly: 3.265 ± 0.754
0.0AspHis: 0.0 ± 0.0
4.082AspIle: 4.082 ± 1.802
3.265AspLys: 3.265 ± 1.202
5.714AspLeu: 5.714 ± 1.118
1.633AspMet: 1.633 ± 1.22
4.898AspAsn: 4.898 ± 1.814
2.449AspPro: 2.449 ± 2.157
2.449AspGln: 2.449 ± 1.411
0.816AspArg: 0.816 ± 0.61
2.449AspSer: 2.449 ± 1.213
4.082AspThr: 4.082 ± 0.52
2.449AspVal: 2.449 ± 0.987
1.633AspTrp: 1.633 ± 1.327
1.633AspTyr: 1.633 ± 0.794
0.0AspXaa: 0.0 ± 0.0
Glu
0.816GluAla: 0.816 ± 0.663
0.0GluCys: 0.0 ± 0.0
4.082GluAsp: 4.082 ± 2.019
6.531GluGlu: 6.531 ± 1.81
7.347GluPhe: 7.347 ± 2.663
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
5.714GluIle: 5.714 ± 2.137
4.898GluLys: 4.898 ± 1.974
1.633GluLeu: 1.633 ± 0.857
2.449GluMet: 2.449 ± 1.242
6.531GluAsn: 6.531 ± 1.552
1.633GluPro: 1.633 ± 0.857
1.633GluGln: 1.633 ± 0.857
0.816GluArg: 0.816 ± 0.719
3.265GluSer: 3.265 ± 1.432
3.265GluThr: 3.265 ± 1.984
4.082GluVal: 4.082 ± 1.224
1.633GluTrp: 1.633 ± 0.483
1.633GluTyr: 1.633 ± 0.816
0.0GluXaa: 0.0 ± 0.0
Phe
1.633PheAla: 1.633 ± 0.887
0.0PheCys: 0.0 ± 0.0
3.265PheAsp: 3.265 ± 2.086
5.714PheGlu: 5.714 ± 2.562
0.816PhePhe: 0.816 ± 0.663
3.265PheGly: 3.265 ± 2.086
0.0PheHis: 0.0 ± 0.0
3.265PheIle: 3.265 ± 1.984
1.633PheLys: 1.633 ± 0.952
2.449PheLeu: 2.449 ± 0.883
1.633PheMet: 1.633 ± 0.857
4.082PheAsn: 4.082 ± 1.676
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
5.714PheArg: 5.714 ± 2.137
3.265PheSer: 3.265 ± 0.906
2.449PheThr: 2.449 ± 1.521
2.449PheVal: 2.449 ± 1.484
0.0PheTrp: 0.0 ± 0.0
2.449PheTyr: 2.449 ± 1.353
0.0PheXaa: 0.0 ± 0.0
Gly
4.898GlyAla: 4.898 ± 2.496
0.816GlyCys: 0.816 ± 0.663
4.082GlyAsp: 4.082 ± 0.751
1.633GlyGlu: 1.633 ± 1.22
0.816GlyPhe: 0.816 ± 0.719
6.531GlyGly: 6.531 ± 2.203
0.816GlyHis: 0.816 ± 0.663
2.449GlyIle: 2.449 ± 1.353
5.714GlyLys: 5.714 ± 1.464
6.531GlyLeu: 6.531 ± 1.084
1.633GlyMet: 1.633 ± 0.887
4.082GlyAsn: 4.082 ± 1.958
2.449GlyPro: 2.449 ± 0.551
1.633GlyGln: 1.633 ± 0.816
2.449GlyArg: 2.449 ± 0.878
9.796GlySer: 9.796 ± 4.412
6.531GlyThr: 6.531 ± 1.713
8.163GlyVal: 8.163 ± 2.303
0.816GlyTrp: 0.816 ± 0.663
4.082GlyTyr: 4.082 ± 1.406
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
2.449HisCys: 2.449 ± 0.987
1.633HisAsp: 1.633 ± 1.22
0.816HisGlu: 0.816 ± 0.663
0.816HisPhe: 0.816 ± 0.663
1.633HisGly: 1.633 ± 0.952
0.0HisHis: 0.0 ± 0.0
0.816HisIle: 0.816 ± 0.663
0.816HisLys: 0.816 ± 0.61
1.633HisLeu: 1.633 ± 0.857
0.816HisMet: 0.816 ± 0.731
0.816HisAsn: 0.816 ± 0.61
0.816HisPro: 0.816 ± 0.663
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
4.082HisSer: 4.082 ± 1.197
0.0HisThr: 0.0 ± 0.0
0.816HisVal: 0.816 ± 0.61
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.265IleAla: 3.265 ± 0.966
0.0IleCys: 0.0 ± 0.0
1.633IleAsp: 1.633 ± 0.794
5.714IleGlu: 5.714 ± 2.612
1.633IlePhe: 1.633 ± 0.483
4.898IleGly: 4.898 ± 1.527
0.816IleHis: 0.816 ± 0.719
3.265IleIle: 3.265 ± 1.186
8.163IleLys: 8.163 ± 1.53
3.265IleLeu: 3.265 ± 1.182
1.633IleMet: 1.633 ± 1.327
3.265IleAsn: 3.265 ± 0.481
2.449IlePro: 2.449 ± 0.968
1.633IleGln: 1.633 ± 0.952
4.082IleArg: 4.082 ± 1.255
3.265IleSer: 3.265 ± 1.984
0.816IleThr: 0.816 ± 0.663
4.898IleVal: 4.898 ± 2.069
1.633IleTrp: 1.633 ± 0.816
6.531IleTyr: 6.531 ± 1.856
0.0IleXaa: 0.0 ± 0.0
Lys
1.633LysAla: 1.633 ± 1.327
1.633LysCys: 1.633 ± 0.483
0.0LysAsp: 0.0 ± 0.0
4.082LysGlu: 4.082 ± 1.518
4.082LysPhe: 4.082 ± 1.802
5.714LysGly: 5.714 ± 1.606
2.449LysHis: 2.449 ± 1.99
5.714LysIle: 5.714 ± 1.723
1.633LysLys: 1.633 ± 1.22
8.98LysLeu: 8.98 ± 2.028
0.0LysMet: 0.0 ± 0.0
3.265LysAsn: 3.265 ± 1.202
4.082LysPro: 4.082 ± 1.661
7.347LysGln: 7.347 ± 2.179
3.265LysArg: 3.265 ± 0.754
6.531LysSer: 6.531 ± 2.381
3.265LysThr: 3.265 ± 1.202
3.265LysVal: 3.265 ± 1.432
0.0LysTrp: 0.0 ± 0.0
1.633LysTyr: 1.633 ± 0.483
0.0LysXaa: 0.0 ± 0.0
Leu
1.633LeuAla: 1.633 ± 0.483
1.633LeuCys: 1.633 ± 1.22
8.163LeuAsp: 8.163 ± 3.168
2.449LeuGlu: 2.449 ± 0.987
2.449LeuPhe: 2.449 ± 0.968
1.633LeuGly: 1.633 ± 0.857
0.816LeuHis: 0.816 ± 0.663
4.898LeuIle: 4.898 ± 1.755
4.898LeuLys: 4.898 ± 1.842
6.531LeuLeu: 6.531 ± 1.385
2.449LeuMet: 2.449 ± 1.411
4.082LeuAsn: 4.082 ± 1.732
5.714LeuPro: 5.714 ± 0.81
3.265LeuGln: 3.265 ± 1.952
2.449LeuArg: 2.449 ± 0.878
2.449LeuSer: 2.449 ± 1.83
5.714LeuThr: 5.714 ± 1.908
8.163LeuVal: 8.163 ± 0.702
2.449LeuTrp: 2.449 ± 1.99
4.082LeuTyr: 4.082 ± 1.515
0.0LeuXaa: 0.0 ± 0.0
Met
0.816MetAla: 0.816 ± 0.719
0.816MetCys: 0.816 ± 0.663
0.816MetAsp: 0.816 ± 0.731
3.265MetGlu: 3.265 ± 0.966
2.449MetPhe: 2.449 ± 0.551
0.816MetGly: 0.816 ± 0.719
0.0MetHis: 0.0 ± 0.0
1.633MetIle: 1.633 ± 0.887
3.265MetLys: 3.265 ± 0.754
1.633MetLeu: 1.633 ± 0.483
0.816MetMet: 0.816 ± 0.719
0.0MetAsn: 0.0 ± 0.0
1.633MetPro: 1.633 ± 0.857
0.816MetGln: 0.816 ± 0.61
1.633MetArg: 1.633 ± 0.816
0.816MetSer: 0.816 ± 0.61
0.816MetThr: 0.816 ± 0.719
4.082MetVal: 4.082 ± 0.751
0.816MetTrp: 0.816 ± 0.663
1.633MetTyr: 1.633 ± 0.483
0.0MetXaa: 0.0 ± 0.0
Asn
5.714AsnAla: 5.714 ± 0.477
1.633AsnCys: 1.633 ± 1.327
4.082AsnAsp: 4.082 ± 1.712
1.633AsnGlu: 1.633 ± 1.438
2.449AsnPhe: 2.449 ± 1.436
5.714AsnGly: 5.714 ± 0.747
0.0AsnHis: 0.0 ± 0.0
4.082AsnIle: 4.082 ± 1.091
6.531AsnLys: 6.531 ± 1.211
6.531AsnLeu: 6.531 ± 1.47
4.082AsnMet: 4.082 ± 0.507
1.633AsnAsn: 1.633 ± 1.461
3.265AsnPro: 3.265 ± 1.202
0.816AsnGln: 0.816 ± 0.61
2.449AsnArg: 2.449 ± 0.883
5.714AsnSer: 5.714 ± 0.81
3.265AsnThr: 3.265 ± 0.928
0.816AsnVal: 0.816 ± 0.731
0.816AsnTrp: 0.816 ± 0.663
0.816AsnTyr: 0.816 ± 0.731
0.0AsnXaa: 0.0 ± 0.0
Pro
0.816ProAla: 0.816 ± 0.731
0.816ProCys: 0.816 ± 0.663
0.0ProAsp: 0.0 ± 0.0
2.449ProGlu: 2.449 ± 0.551
3.265ProPhe: 3.265 ± 0.481
3.265ProGly: 3.265 ± 0.906
0.0ProHis: 0.0 ± 0.0
2.449ProIle: 2.449 ± 0.883
4.082ProLys: 4.082 ± 1.294
4.082ProLeu: 4.082 ± 0.746
2.449ProMet: 2.449 ± 0.892
1.633ProAsn: 1.633 ± 0.857
1.633ProPro: 1.633 ± 0.857
0.816ProGln: 0.816 ± 0.61
2.449ProArg: 2.449 ± 0.883
3.265ProSer: 3.265 ± 0.928
3.265ProThr: 3.265 ± 0.785
3.265ProVal: 3.265 ± 2.211
0.0ProTrp: 0.0 ± 0.0
2.449ProTyr: 2.449 ± 0.551
0.0ProXaa: 0.0 ± 0.0
Gln
5.714GlnAla: 5.714 ± 1.996
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.633GlnGlu: 1.633 ± 1.327
4.082GlnPhe: 4.082 ± 2.044
4.898GlnGly: 4.898 ± 1.847
1.633GlnHis: 1.633 ± 0.887
1.633GlnIle: 1.633 ± 0.483
0.816GlnLys: 0.816 ± 0.61
2.449GlnLeu: 2.449 ± 1.83
0.816GlnMet: 0.816 ± 0.663
0.816GlnAsn: 0.816 ± 0.663
0.816GlnPro: 0.816 ± 0.61
3.265GlnGln: 3.265 ± 1.952
0.816GlnArg: 0.816 ± 0.731
1.633GlnSer: 1.633 ± 0.857
0.816GlnThr: 0.816 ± 0.61
3.265GlnVal: 3.265 ± 0.754
0.816GlnTrp: 0.816 ± 0.663
0.816GlnTyr: 0.816 ± 0.61
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.816ArgCys: 0.816 ± 0.663
3.265ArgAsp: 3.265 ± 0.481
3.265ArgGlu: 3.265 ± 0.906
0.0ArgPhe: 0.0 ± 0.0
2.449ArgGly: 2.449 ± 0.553
2.449ArgHis: 2.449 ± 1.248
2.449ArgIle: 2.449 ± 0.883
4.082ArgLys: 4.082 ± 1.108
4.082ArgLeu: 4.082 ± 2.582
0.0ArgMet: 0.0 ± 0.0
4.082ArgAsn: 4.082 ± 1.661
0.816ArgPro: 0.816 ± 0.61
0.816ArgGln: 0.816 ± 0.61
0.816ArgArg: 0.816 ± 0.731
2.449ArgSer: 2.449 ± 1.521
4.082ArgThr: 4.082 ± 1.712
2.449ArgVal: 2.449 ± 1.83
0.816ArgTrp: 0.816 ± 0.663
1.633ArgTyr: 1.633 ± 0.887
0.0ArgXaa: 0.0 ± 0.0
Ser
3.265SerAla: 3.265 ± 1.749
1.633SerCys: 1.633 ± 0.887
2.449SerAsp: 2.449 ± 0.551
4.082SerGlu: 4.082 ± 0.746
1.633SerPhe: 1.633 ± 1.438
5.714SerGly: 5.714 ± 1.464
1.633SerHis: 1.633 ± 0.483
3.265SerIle: 3.265 ± 1.182
4.082SerLys: 4.082 ± 0.738
4.082SerLeu: 4.082 ± 3.05
2.449SerMet: 2.449 ± 0.878
3.265SerAsn: 3.265 ± 1.486
4.082SerPro: 4.082 ± 0.738
1.633SerGln: 1.633 ± 0.483
3.265SerArg: 3.265 ± 1.486
6.531SerSer: 6.531 ± 1.688
4.898SerThr: 4.898 ± 1.026
8.163SerVal: 8.163 ± 1.672
2.449SerTrp: 2.449 ± 1.353
4.082SerTyr: 4.082 ± 1.279
0.0SerXaa: 0.0 ± 0.0
Thr
3.265ThrAla: 3.265 ± 0.754
2.449ThrCys: 2.449 ± 1.213
4.082ThrAsp: 4.082 ± 1.197
1.633ThrGlu: 1.633 ± 0.794
3.265ThrPhe: 3.265 ± 2.876
3.265ThrGly: 3.265 ± 1.432
0.816ThrHis: 0.816 ± 0.61
4.898ThrIle: 4.898 ± 1.14
4.082ThrLys: 4.082 ± 1.197
1.633ThrLeu: 1.633 ± 0.816
2.449ThrMet: 2.449 ± 0.551
4.082ThrAsn: 4.082 ± 1.347
2.449ThrPro: 2.449 ± 0.883
3.265ThrGln: 3.265 ± 0.754
1.633ThrArg: 1.633 ± 0.887
3.265ThrSer: 3.265 ± 1.952
2.449ThrThr: 2.449 ± 0.968
4.082ThrVal: 4.082 ± 1.294
0.0ThrTrp: 0.0 ± 0.0
3.265ThrTyr: 3.265 ± 1.359
0.0ThrXaa: 0.0 ± 0.0
Val
5.714ValAla: 5.714 ± 1.996
1.633ValCys: 1.633 ± 0.794
3.265ValAsp: 3.265 ± 0.481
2.449ValGlu: 2.449 ± 0.551
3.265ValPhe: 3.265 ± 1.359
10.612ValGly: 10.612 ± 3.996
3.265ValHis: 3.265 ± 1.589
4.082ValIle: 4.082 ± 2.361
1.633ValLys: 1.633 ± 1.22
8.163ValLeu: 8.163 ± 1.003
0.816ValMet: 0.816 ± 0.663
6.531ValAsn: 6.531 ± 2.039
0.0ValPro: 0.0 ± 0.0
0.816ValGln: 0.816 ± 0.731
4.898ValArg: 4.898 ± 1.429
4.898ValSer: 4.898 ± 1.835
4.898ValThr: 4.898 ± 1.472
7.347ValVal: 7.347 ± 1.078
0.816ValTrp: 0.816 ± 0.663
1.633ValTyr: 1.633 ± 1.22
0.0ValXaa: 0.0 ± 0.0
Trp
1.633TrpAla: 1.633 ± 0.483
0.0TrpCys: 0.0 ± 0.0
2.449TrpAsp: 2.449 ± 0.987
0.816TrpGlu: 0.816 ± 0.663
0.816TrpPhe: 0.816 ± 0.719
1.633TrpGly: 1.633 ± 0.483
0.0TrpHis: 0.0 ± 0.0
0.816TrpIle: 0.816 ± 0.663
1.633TrpLys: 1.633 ± 1.327
0.816TrpLeu: 0.816 ± 0.663
0.816TrpMet: 0.816 ± 0.663
0.816TrpAsn: 0.816 ± 0.663
0.0TrpPro: 0.0 ± 0.0
1.633TrpGln: 1.633 ± 0.857
0.816TrpArg: 0.816 ± 0.663
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.449TrpTyr: 2.449 ± 1.386
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.449TyrAla: 2.449 ± 0.553
2.449TyrCys: 2.449 ± 1.484
4.082TyrAsp: 4.082 ± 1.197
4.082TyrGlu: 4.082 ± 2.582
0.0TyrPhe: 0.0 ± 0.0
3.265TyrGly: 3.265 ± 0.928
2.449TyrHis: 2.449 ± 0.878
4.082TyrIle: 4.082 ± 0.738
4.082TyrLys: 4.082 ± 2.258
1.633TyrLeu: 1.633 ± 0.483
0.816TyrMet: 0.816 ± 0.61
3.265TyrAsn: 3.265 ± 0.906
1.633TyrPro: 1.633 ± 0.857
2.449TyrGln: 2.449 ± 0.551
0.816TyrArg: 0.816 ± 0.663
3.265TyrSer: 3.265 ± 1.432
0.816TyrThr: 0.816 ± 0.61
0.0TyrVal: 0.0 ± 0.0
0.816TyrTrp: 0.816 ± 0.731
1.633TyrTyr: 1.633 ± 1.327
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1226 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski