Amino acid dipepetide frequency for Maioricimonas rarisocia

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.048AlaAla: 13.048 ± 0.103	1.166AlaCys: 1.166 ± 0.026	6.718AlaAsp: 6.718 ± 0.085	7.174AlaGlu: 7.174 ± 0.072	3.322AlaPhe: 3.322 ± 0.04	8.908AlaGly: 8.908 ± 0.09	1.926AlaHis: 1.926 ± 0.035	4.872AlaIle: 4.872 ± 0.055	2.403AlaLys: 2.403 ± 0.041	8.864AlaLeu: 8.864 ± 0.081	2.339AlaMet: 2.339 ± 0.037	2.481AlaAsn: 2.481 ± 0.04	4.67AlaPro: 4.67 ± 0.057	2.918AlaGln: 2.918 ± 0.042	7.207AlaArg: 7.207 ± 0.077	5.849AlaSer: 5.849 ± 0.055	5.755AlaThr: 5.755 ± 0.057	7.703AlaVal: 7.703 ± 0.074	1.471AlaTrp: 1.471 ± 0.03	1.929AlaTyr: 1.929 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.95CysAla: 0.95 ± 0.023	0.245CysCys: 0.245 ± 0.014	0.689CysAsp: 0.689 ± 0.017	0.692CysGlu: 0.692 ± 0.021	0.397CysPhe: 0.397 ± 0.013	1.152CysGly: 1.152 ± 0.026	0.458CysHis: 0.458 ± 0.017	0.434CysIle: 0.434 ± 0.014	0.241CysLys: 0.241 ± 0.011	1.172CysLeu: 1.172 ± 0.026	0.195CysMet: 0.195 ± 0.011	0.294CysAsn: 0.294 ± 0.011	0.699CysPro: 0.699 ± 0.018	0.346CysGln: 0.346 ± 0.012	1.007CysArg: 1.007 ± 0.023	0.656CysSer: 0.656 ± 0.019	0.574CysThr: 0.574 ± 0.018	0.816CysVal: 0.816 ± 0.021	0.196CysTrp: 0.196 ± 0.01	0.307CysTyr: 0.307 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.677AspAla: 6.677 ± 0.067	0.623AspCys: 0.623 ± 0.018	4.483AspAsp: 4.483 ± 0.056	4.964AspGlu: 4.964 ± 0.063	2.279AspPhe: 2.279 ± 0.035	5.883AspGly: 5.883 ± 0.083	1.491AspHis: 1.491 ± 0.034	2.408AspIle: 2.408 ± 0.033	1.212AspLys: 1.212 ± 0.03	5.941AspLeu: 5.941 ± 0.06	1.064AspMet: 1.064 ± 0.02	1.417AspAsn: 1.417 ± 0.029	3.831AspPro: 3.831 ± 0.048	2.126AspGln: 2.126 ± 0.032	5.174AspArg: 5.174 ± 0.055	3.236AspSer: 3.236 ± 0.042	2.537AspThr: 2.537 ± 0.066	5.005AspVal: 5.005 ± 0.064	1.172AspTrp: 1.172 ± 0.023	1.49AspTyr: 1.49 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	6.67GluAla: 6.67 ± 0.075	0.588GluCys: 0.588 ± 0.019	3.324GluAsp: 3.324 ± 0.039	4.654GluGlu: 4.654 ± 0.061	2.522GluPhe: 2.522 ± 0.042	4.352GluGly: 4.352 ± 0.052	1.585GluHis: 1.585 ± 0.032	3.346GluIle: 3.346 ± 0.038	2.14GluLys: 2.14 ± 0.037	7.311GluLeu: 7.311 ± 0.078	1.562GluMet: 1.562 ± 0.027	1.879GluAsn: 1.879 ± 0.026	3.572GluPro: 3.572 ± 0.053	3.566GluGln: 3.566 ± 0.048	5.276GluArg: 5.276 ± 0.063	4.225GluSer: 4.225 ± 0.045	4.058GluThr: 4.058 ± 0.049	4.351GluVal: 4.351 ± 0.046	0.994GluTrp: 0.994 ± 0.022	1.595GluTyr: 1.595 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.612PheAla: 3.612 ± 0.042	0.47PheCys: 0.47 ± 0.015	2.844PheAsp: 2.844 ± 0.038	2.59PheGlu: 2.59 ± 0.028	1.257PhePhe: 1.257 ± 0.026	3.252PheGly: 3.252 ± 0.044	0.821PheHis: 0.821 ± 0.02	1.285PheIle: 1.285 ± 0.025	0.666PheLys: 0.666 ± 0.018	3.418PheLeu: 3.418 ± 0.045	0.614PheMet: 0.614 ± 0.018	0.967PheAsn: 0.967 ± 0.026	1.736PhePro: 1.736 ± 0.029	1.046PheGln: 1.046 ± 0.022	2.783PheArg: 2.783 ± 0.037	2.081PheSer: 2.081 ± 0.036	1.851PheThr: 1.851 ± 0.043	2.847PheVal: 2.847 ± 0.038	0.542PheTrp: 0.542 ± 0.017	0.848PheTyr: 0.848 ± 0.021	0.0PheXaa: 0.0 ± 0.0
Gly	6.133GlyAla: 6.133 ± 0.095	1.055GlyCys: 1.055 ± 0.027	4.936GlyAsp: 4.936 ± 0.069	5.35GlyGlu: 5.35 ± 0.056	2.911GlyPhe: 2.911 ± 0.039	6.755GlyGly: 6.755 ± 0.143	1.915GlyHis: 1.915 ± 0.034	3.835GlyIle: 3.835 ± 0.05	2.728GlyLys: 2.728 ± 0.04	7.512GlyLeu: 7.512 ± 0.074	2.037GlyMet: 2.037 ± 0.033	2.527GlyAsn: 2.527 ± 0.055	3.724GlyPro: 3.724 ± 0.043	3.086GlyGln: 3.086 ± 0.046	6.335GlyArg: 6.335 ± 0.064	4.756GlySer: 4.756 ± 0.067	5.061GlyThr: 5.061 ± 0.053	5.458GlyVal: 5.458 ± 0.076	1.458GlyTrp: 1.458 ± 0.029	2.164GlyTyr: 2.164 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	2.143HisAla: 2.143 ± 0.031	0.337HisCys: 0.337 ± 0.013	1.472HisAsp: 1.472 ± 0.031	1.537HisGlu: 1.537 ± 0.03	0.928HisPhe: 0.928 ± 0.022	2.004HisGly: 2.004 ± 0.041	0.71HisHis: 0.71 ± 0.022	0.876HisIle: 0.876 ± 0.02	0.51HisLys: 0.51 ± 0.015	2.325HisLeu: 2.325 ± 0.036	0.391HisMet: 0.391 ± 0.012	0.647HisAsn: 0.647 ± 0.02	1.605HisPro: 1.605 ± 0.029	0.769HisGln: 0.769 ± 0.018	1.925HisArg: 1.925 ± 0.033	1.257HisSer: 1.257 ± 0.023	1.017HisThr: 1.017 ± 0.024	1.821HisVal: 1.821 ± 0.027	0.455HisTrp: 0.455 ± 0.016	0.624HisTyr: 0.624 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	5.253IleAla: 5.253 ± 0.058	0.615IleCys: 0.615 ± 0.017	3.681IleAsp: 3.681 ± 0.043	3.538IleGlu: 3.538 ± 0.045	1.291IlePhe: 1.291 ± 0.025	3.822IleGly: 3.822 ± 0.048	1.044IleHis: 1.044 ± 0.022	1.618IleIle: 1.618 ± 0.031	0.902IleLys: 0.902 ± 0.02	3.932IleLeu: 3.932 ± 0.05	0.625IleMet: 0.625 ± 0.019	1.272IleAsn: 1.272 ± 0.03	2.58IlePro: 2.58 ± 0.034	1.306IleGln: 1.306 ± 0.028	3.724IleArg: 3.724 ± 0.041	2.44IleSer: 2.44 ± 0.036	2.332IleThr: 2.332 ± 0.042	3.818IleVal: 3.818 ± 0.049	0.602IleTrp: 0.602 ± 0.018	0.986IleTyr: 0.986 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	2.508LysAla: 2.508 ± 0.043	0.234LysCys: 0.234 ± 0.011	1.356LysAsp: 1.356 ± 0.03	1.599LysGlu: 1.599 ± 0.031	0.804LysPhe: 0.804 ± 0.02	1.811LysGly: 1.811 ± 0.034	0.623LysHis: 0.623 ± 0.018	1.177LysIle: 1.177 ± 0.025	1.15LysLys: 1.15 ± 0.039	2.804LysLeu: 2.804 ± 0.045	0.597LysMet: 0.597 ± 0.016	0.7LysAsn: 0.7 ± 0.018	1.802LysPro: 1.802 ± 0.036	1.276LysGln: 1.276 ± 0.027	2.0LysArg: 2.0 ± 0.034	1.633LysSer: 1.633 ± 0.027	1.518LysThr: 1.518 ± 0.031	1.894LysVal: 1.894 ± 0.031	0.441LysTrp: 0.441 ± 0.014	0.733LysTyr: 0.733 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	11.08LeuAla: 11.08 ± 0.101	1.161LeuCys: 1.161 ± 0.023	6.071LeuAsp: 6.071 ± 0.05	6.525LeuGlu: 6.525 ± 0.07	3.464LeuPhe: 3.464 ± 0.05	6.955LeuGly: 6.955 ± 0.066	2.097LeuHis: 2.097 ± 0.036	4.412LeuIle: 4.412 ± 0.049	3.165LeuLys: 3.165 ± 0.041	10.915LeuLeu: 10.915 ± 0.1	2.013LeuMet: 2.013 ± 0.032	2.538LeuAsn: 2.538 ± 0.032	5.808LeuPro: 5.808 ± 0.067	4.008LeuGln: 4.008 ± 0.049	7.084LeuArg: 7.084 ± 0.076	5.785LeuSer: 5.785 ± 0.044	5.86LeuThr: 5.86 ± 0.066	7.167LeuVal: 7.167 ± 0.064	1.324LeuTrp: 1.324 ± 0.029	2.112LeuTyr: 2.112 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	2.029MetAla: 2.029 ± 0.034	0.198MetCys: 0.198 ± 0.011	0.961MetAsp: 0.961 ± 0.019	0.972MetGlu: 0.972 ± 0.02	0.732MetPhe: 0.732 ± 0.018	1.344MetGly: 1.344 ± 0.027	0.503MetHis: 0.503 ± 0.016	1.041MetIle: 1.041 ± 0.023	0.719MetLys: 0.719 ± 0.019	2.285MetLeu: 2.285 ± 0.038	0.491MetMet: 0.491 ± 0.016	0.732MetAsn: 0.732 ± 0.019	1.324MetPro: 1.324 ± 0.026	0.964MetGln: 0.964 ± 0.021	1.486MetArg: 1.486 ± 0.024	1.488MetSer: 1.488 ± 0.028	1.515MetThr: 1.515 ± 0.026	1.357MetVal: 1.357 ± 0.031	0.249MetTrp: 0.249 ± 0.011	0.422MetTyr: 0.422 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.603AsnAla: 2.603 ± 0.039	0.352AsnCys: 0.352 ± 0.012	1.607AsnAsp: 1.607 ± 0.028	1.606AsnGlu: 1.606 ± 0.032	0.893AsnPhe: 0.893 ± 0.023	2.579AsnGly: 2.579 ± 0.044	0.638AsnHis: 0.638 ± 0.019	1.148AsnIle: 1.148 ± 0.026	0.471AsnLys: 0.471 ± 0.014	2.596AsnLeu: 2.596 ± 0.041	0.497AsnMet: 0.497 ± 0.016	0.806AsnAsn: 0.806 ± 0.029	1.8AsnPro: 1.8 ± 0.032	0.883AsnGln: 0.883 ± 0.022	2.295AsnArg: 2.295 ± 0.041	1.493AsnSer: 1.493 ± 0.03	1.28AsnThr: 1.28 ± 0.032	2.221AsnVal: 2.221 ± 0.042	0.481AsnTrp: 0.481 ± 0.015	0.719AsnTyr: 0.719 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	6.261ProAla: 6.261 ± 0.074	0.424ProCys: 0.424 ± 0.016	4.242ProAsp: 4.242 ± 0.049	4.812ProGlu: 4.812 ± 0.054	1.96ProPhe: 1.96 ± 0.033	4.675ProGly: 4.675 ± 0.041	1.402ProHis: 1.402 ± 0.03	2.21ProIle: 2.21 ± 0.036	1.373ProLys: 1.373 ± 0.03	5.033ProLeu: 5.033 ± 0.059	1.047ProMet: 1.047 ± 0.024	1.446ProAsn: 1.446 ± 0.031	3.522ProPro: 3.522 ± 0.063	2.246ProGln: 2.246 ± 0.033	3.425ProArg: 3.425 ± 0.045	3.134ProSer: 3.134 ± 0.041	2.946ProThr: 2.946 ± 0.036	4.556ProVal: 4.556 ± 0.052	0.759ProTrp: 0.759 ± 0.021	1.184ProTyr: 1.184 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.842GlnAla: 3.842 ± 0.048	0.378GlnCys: 0.378 ± 0.013	1.595GlnAsp: 1.595 ± 0.03	2.172GlnGlu: 2.172 ± 0.035	1.506GlnPhe: 1.506 ± 0.027	2.257GlnGly: 2.257 ± 0.035	0.923GlnHis: 0.923 ± 0.019	2.056GlnIle: 2.056 ± 0.025	1.189GlnLys: 1.189 ± 0.026	4.21GlnLeu: 4.21 ± 0.051	0.9GlnMet: 0.9 ± 0.02	0.991GlnAsn: 0.991 ± 0.021	2.507GlnPro: 2.507 ± 0.037	2.432GlnGln: 2.432 ± 0.048	3.072GlnArg: 3.072 ± 0.046	2.169GlnSer: 2.169 ± 0.033	2.153GlnThr: 2.153 ± 0.033	2.638GlnVal: 2.638 ± 0.036	0.55GlnTrp: 0.55 ± 0.014	0.836GlnTyr: 0.836 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	5.822ArgAla: 5.822 ± 0.065	0.823ArgCys: 0.823 ± 0.023	4.529ArgAsp: 4.529 ± 0.054	5.214ArgGlu: 5.214 ± 0.062	3.202ArgPhe: 3.202 ± 0.041	4.851ArgGly: 4.851 ± 0.045	1.94ArgHis: 1.94 ± 0.035	3.996ArgIle: 3.996 ± 0.042	2.432ArgLys: 2.432 ± 0.039	8.329ArgLeu: 8.329 ± 0.078	1.899ArgMet: 1.899 ± 0.027	2.215ArgAsn: 2.215 ± 0.037	4.098ArgPro: 4.098 ± 0.048	3.552ArgGln: 3.552 ± 0.046	6.758ArgArg: 6.758 ± 0.077	4.516ArgSer: 4.516 ± 0.051	4.166ArgThr: 4.166 ± 0.056	5.095ArgVal: 5.095 ± 0.056	1.33ArgTrp: 1.33 ± 0.028	2.049ArgTyr: 2.049 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.449SerAla: 5.449 ± 0.061	0.666SerCys: 0.666 ± 0.019	3.782SerAsp: 3.782 ± 0.044	3.771SerGlu: 3.771 ± 0.047	1.928SerPhe: 1.928 ± 0.038	5.622SerGly: 5.622 ± 0.075	1.322SerHis: 1.322 ± 0.027	2.527SerIle: 2.527 ± 0.037	1.326SerLys: 1.326 ± 0.03	5.765SerLeu: 5.765 ± 0.053	1.229SerMet: 1.229 ± 0.024	1.567SerAsn: 1.567 ± 0.029	3.683SerPro: 3.683 ± 0.045	2.116SerGln: 2.116 ± 0.03	4.612SerArg: 4.612 ± 0.05	3.78SerSer: 3.78 ± 0.047	3.261SerThr: 3.261 ± 0.063	4.146SerVal: 4.146 ± 0.047	0.825SerTrp: 0.825 ± 0.021	1.234SerTyr: 1.234 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	5.63ThrAla: 5.63 ± 0.064	0.633ThrCys: 0.633 ± 0.02	3.407ThrAsp: 3.407 ± 0.046	3.08ThrGlu: 3.08 ± 0.045	2.16ThrPhe: 2.16 ± 0.038	5.24ThrGly: 5.24 ± 0.101	1.182ThrHis: 1.182 ± 0.026	2.924ThrIle: 2.924 ± 0.043	1.126ThrLys: 1.126 ± 0.028	5.787ThrLeu: 5.787 ± 0.068	1.047ThrMet: 1.047 ± 0.023	1.306ThrAsn: 1.306 ± 0.029	3.578ThrPro: 3.578 ± 0.049	1.667ThrGln: 1.667 ± 0.027	3.588ThrArg: 3.588 ± 0.044	3.446ThrSer: 3.446 ± 0.043	3.208ThrThr: 3.208 ± 0.089	4.548ThrVal: 4.548 ± 0.081	0.914ThrTrp: 0.914 ± 0.022	1.32ThrTyr: 1.32 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.876ValAla: 7.876 ± 0.071	0.977ValCys: 0.977 ± 0.026	4.867ValAsp: 4.867 ± 0.057	4.949ValGlu: 4.949 ± 0.048	2.44ValPhe: 2.44 ± 0.034	5.182ValGly: 5.182 ± 0.054	1.641ValHis: 1.641 ± 0.026	3.592ValIle: 3.592 ± 0.042	1.79ValLys: 1.79 ± 0.029	7.251ValLeu: 7.251 ± 0.065	1.462ValMet: 1.462 ± 0.025	1.941ValAsn: 1.941 ± 0.036	4.162ValPro: 4.162 ± 0.05	2.453ValGln: 2.453 ± 0.027	5.69ValArg: 5.69 ± 0.055	4.343ValSer: 4.343 ± 0.059	4.704ValThr: 4.704 ± 0.109	5.998ValVal: 5.998 ± 0.065	1.069ValTrp: 1.069 ± 0.023	1.648ValTyr: 1.648 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.038TrpAla: 1.038 ± 0.021	0.228TrpCys: 0.228 ± 0.012	0.854TrpAsp: 0.854 ± 0.024	0.818TrpGlu: 0.818 ± 0.019	0.566TrpPhe: 0.566 ± 0.015	1.023TrpGly: 1.023 ± 0.024	0.486TrpHis: 0.486 ± 0.015	0.825TrpIle: 0.825 ± 0.021	0.633TrpLys: 0.633 ± 0.018	1.79TrpLeu: 1.79 ± 0.035	0.436TrpMet: 0.436 ± 0.014	0.579TrpAsn: 0.579 ± 0.015	0.819TrpPro: 0.819 ± 0.022	0.754TrpGln: 0.754 ± 0.021	1.142TrpArg: 1.142 ± 0.026	1.056TrpSer: 1.056 ± 0.025	0.928TrpThr: 0.928 ± 0.022	0.872TrpVal: 0.872 ± 0.022	0.316TrpTrp: 0.316 ± 0.012	0.408TrpTyr: 0.408 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.101TyrAla: 2.101 ± 0.036	0.346TyrCys: 0.346 ± 0.015	1.596TyrAsp: 1.596 ± 0.037	1.553TyrGlu: 1.553 ± 0.028	0.97TyrPhe: 0.97 ± 0.025	2.07TyrGly: 2.07 ± 0.038	0.646TyrHis: 0.646 ± 0.019	0.8TyrIle: 0.8 ± 0.019	0.486TyrLys: 0.486 ± 0.015	2.306TyrLeu: 2.306 ± 0.035	0.365TyrMet: 0.365 ± 0.015	0.661TyrAsn: 0.661 ± 0.018	1.135TyrPro: 1.135 ± 0.026	0.862TyrGln: 0.862 ± 0.023	2.232TyrArg: 2.232 ± 0.039	1.265TyrSer: 1.265 ± 0.029	1.069TyrThr: 1.069 ± 0.024	1.724TyrVal: 1.724 ± 0.027	0.422TyrTrp: 0.422 ± 0.013	0.726TyrTyr: 0.726 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5804 proteins (2193700 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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