Amino acid dipepetide frequency for Thrips-associated genomovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.149AlaAla: 1.149 ± 0.875
2.299AlaCys: 2.299 ± 1.026
2.299AlaAsp: 2.299 ± 1.026
3.448AlaGlu: 3.448 ± 0.34
0.0AlaPhe: 0.0 ± 0.0
6.897AlaGly: 6.897 ± 1.625
0.0AlaHis: 0.0 ± 0.0
4.598AlaIle: 4.598 ± 2.003
2.299AlaLys: 2.299 ± 1.749
2.299AlaLeu: 2.299 ± 1.749
2.299AlaMet: 2.299 ± 1.026
3.448AlaAsn: 3.448 ± 0.34
6.897AlaPro: 6.897 ± 0.68
0.0AlaGln: 0.0 ± 0.0
4.598AlaArg: 4.598 ± 0.713
9.195AlaSer: 9.195 ± 0.13
5.747AlaThr: 5.747 ± 3.008
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
1.149AlaTyr: 1.149 ± 0.875
0.0AlaXaa: 0.0 ± 0.0
Cys
1.149CysAla: 1.149 ± 0.827
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.149CysIle: 1.149 ± 0.875
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.448CysAsn: 3.448 ± 1.554
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.299CysSer: 2.299 ± 1.026
1.149CysThr: 1.149 ± 0.827
1.149CysVal: 1.149 ± 0.827
0.0CysTrp: 0.0 ± 0.0
1.149CysTyr: 1.149 ± 0.875
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
12.644AspAsp: 12.644 ± 0.364
4.598AspGlu: 4.598 ± 0.713
3.448AspPhe: 3.448 ± 0.34
11.494AspGly: 11.494 ± 5.13
0.0AspHis: 0.0 ± 0.0
1.149AspIle: 1.149 ± 0.827
3.448AspLys: 3.448 ± 1.344
11.494AspLeu: 11.494 ± 1.874
1.149AspMet: 1.149 ± 0.827
2.299AspAsn: 2.299 ± 1.026
1.149AspPro: 1.149 ± 0.827
0.0AspGln: 0.0 ± 0.0
8.046AspArg: 8.046 ± 2.265
3.448AspSer: 3.448 ± 0.34
4.598AspThr: 4.598 ± 3.499
2.299AspVal: 2.299 ± 1.026
5.747AspTrp: 5.747 ± 1.506
3.448AspTyr: 3.448 ± 0.34
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
1.149GluCys: 1.149 ± 0.827
2.299GluAsp: 2.299 ± 1.026
4.598GluGlu: 4.598 ± 0.713
5.747GluPhe: 5.747 ± 2.5
2.299GluGly: 2.299 ± 1.026
2.299GluHis: 2.299 ± 1.026
2.299GluIle: 2.299 ± 1.026
3.448GluLys: 3.448 ± 0.34
4.598GluLeu: 4.598 ± 2.052
0.0GluMet: 0.0 ± 0.0
2.299GluAsn: 2.299 ± 0.693
0.0GluPro: 0.0 ± 0.0
2.299GluGln: 2.299 ± 1.026
3.448GluArg: 3.448 ± 0.34
2.299GluSer: 2.299 ± 0.693
8.046GluThr: 8.046 ± 1.993
2.299GluVal: 2.299 ± 1.026
1.149GluTrp: 1.149 ± 0.827
1.149GluTyr: 1.149 ± 0.827
0.0GluXaa: 0.0 ± 0.0
Phe
2.299PheAla: 2.299 ± 1.749
0.0PheCys: 0.0 ± 0.0
9.195PheAsp: 9.195 ± 1.426
3.448PheGlu: 3.448 ± 1.554
4.598PhePhe: 4.598 ± 2.052
1.149PheGly: 1.149 ± 0.827
3.448PheHis: 3.448 ± 0.34
1.149PheIle: 1.149 ± 0.875
3.448PheLys: 3.448 ± 0.34
0.0PheLeu: 0.0 ± 0.0
2.299PheMet: 2.299 ± 1.026
1.149PheAsn: 1.149 ± 0.827
2.299PhePro: 2.299 ± 1.026
0.0PheGln: 0.0 ± 0.0
4.598PheArg: 4.598 ± 0.713
1.149PheSer: 1.149 ± 0.875
4.598PheThr: 4.598 ± 0.713
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
2.299PheTyr: 2.299 ± 0.693
0.0PheXaa: 0.0 ± 0.0
Gly
6.897GlyAla: 6.897 ± 2.547
2.299GlyCys: 2.299 ± 1.026
9.195GlyAsp: 9.195 ± 1.524
2.299GlyGlu: 2.299 ± 1.026
1.149GlyPhe: 1.149 ± 0.875
8.046GlyGly: 8.046 ± 2.254
2.299GlyHis: 2.299 ± 1.026
2.299GlyIle: 2.299 ± 1.026
8.046GlyLys: 8.046 ± 3.799
6.897GlyLeu: 6.897 ± 2.323
2.299GlyMet: 2.299 ± 1.749
2.299GlyAsn: 2.299 ± 1.749
1.149GlyPro: 1.149 ± 1.029
2.299GlyGln: 2.299 ± 1.654
11.494GlyArg: 11.494 ± 4.103
5.747GlySer: 5.747 ± 1.683
1.149GlyThr: 1.149 ± 0.875
3.448GlyVal: 3.448 ± 2.624
4.598GlyTrp: 4.598 ± 0.842
1.149GlyTyr: 1.149 ± 0.827
0.0GlyXaa: 0.0 ± 0.0
His
4.598HisAla: 4.598 ± 2.052
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
5.747HisGlu: 5.747 ± 1.254
3.448HisPhe: 3.448 ± 0.34
2.299HisGly: 2.299 ± 1.026
2.299HisHis: 2.299 ± 1.026
1.149HisIle: 1.149 ± 0.875
1.149HisLys: 1.149 ± 0.827
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.299HisPro: 2.299 ± 1.749
0.0HisGln: 0.0 ± 0.0
1.149HisArg: 1.149 ± 0.875
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
3.448HisTyr: 3.448 ± 1.554
0.0HisXaa: 0.0 ± 0.0
Ile
1.149IleAla: 1.149 ± 0.875
2.299IleCys: 2.299 ± 0.693
5.747IleAsp: 5.747 ± 1.254
4.598IleGlu: 4.598 ± 0.713
3.448IlePhe: 3.448 ± 1.25
2.299IleGly: 2.299 ± 1.026
1.149IleHis: 1.149 ± 0.875
3.448IleIle: 3.448 ± 0.34
1.149IleLys: 1.149 ± 0.827
5.747IleLeu: 5.747 ± 1.254
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
3.448IleArg: 3.448 ± 0.34
1.149IleSer: 1.149 ± 0.875
3.448IleThr: 3.448 ± 1.344
2.299IleVal: 2.299 ± 1.026
0.0IleTrp: 0.0 ± 0.0
1.149IleTyr: 1.149 ± 0.827
0.0IleXaa: 0.0 ± 0.0
Lys
1.149LysAla: 1.149 ± 0.875
0.0LysCys: 0.0 ± 0.0
3.448LysAsp: 3.448 ± 1.554
1.149LysGlu: 1.149 ± 0.875
1.149LysPhe: 1.149 ± 0.875
4.598LysGly: 4.598 ± 0.842
4.598LysHis: 4.598 ± 0.713
3.448LysIle: 3.448 ± 0.34
5.747LysLys: 5.747 ± 3.008
1.149LysLeu: 1.149 ± 0.875
1.149LysMet: 1.149 ± 0.641
2.299LysAsn: 2.299 ± 0.693
5.747LysPro: 5.747 ± 2.5
1.149LysGln: 1.149 ± 0.827
3.448LysArg: 3.448 ± 2.624
0.0LysSer: 0.0 ± 0.0
8.046LysThr: 8.046 ± 4.734
0.0LysVal: 0.0 ± 0.0
1.149LysTrp: 1.149 ± 0.827
3.448LysTyr: 3.448 ± 1.554
0.0LysXaa: 0.0 ± 0.0
Leu
11.494LeuAla: 11.494 ± 2.507
0.0LeuCys: 0.0 ± 0.0
5.747LeuAsp: 5.747 ± 1.683
0.0LeuGlu: 0.0 ± 0.0
3.448LeuPhe: 3.448 ± 1.344
5.747LeuGly: 5.747 ± 3.04
2.299LeuHis: 2.299 ± 1.026
1.149LeuIle: 1.149 ± 0.875
3.448LeuLys: 3.448 ± 2.624
1.149LeuLeu: 1.149 ± 0.875
0.0LeuMet: 0.0 ± 0.0
1.149LeuAsn: 1.149 ± 0.875
1.149LeuPro: 1.149 ± 1.029
2.299LeuGln: 2.299 ± 1.026
5.747LeuArg: 5.747 ± 1.254
3.448LeuSer: 3.448 ± 1.344
6.897LeuThr: 6.897 ± 0.68
3.448LeuVal: 3.448 ± 1.554
2.299LeuTrp: 2.299 ± 0.693
2.299LeuTyr: 2.299 ± 1.749
0.0LeuXaa: 0.0 ± 0.0
Met
1.149MetAla: 1.149 ± 0.875
0.0MetCys: 0.0 ± 0.0
1.149MetAsp: 1.149 ± 0.875
1.149MetGlu: 1.149 ± 0.827
1.149MetPhe: 1.149 ± 0.875
2.299MetGly: 2.299 ± 0.693
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.299MetLys: 2.299 ± 1.749
3.448MetLeu: 3.448 ± 0.34
0.0MetMet: 0.0 ± 0.0
1.149MetAsn: 1.149 ± 0.875
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
2.299MetArg: 2.299 ± 1.026
0.0MetSer: 0.0 ± 0.0
1.149MetThr: 1.149 ± 0.875
5.747MetVal: 5.747 ± 2.5
0.0MetTrp: 0.0 ± 0.0
1.149MetTyr: 1.149 ± 0.875
0.0MetXaa: 0.0 ± 0.0
Asn
3.448AsnAla: 3.448 ± 1.554
1.149AsnCys: 1.149 ± 0.827
4.598AsnAsp: 4.598 ± 2.052
1.149AsnGlu: 1.149 ± 0.875
0.0AsnPhe: 0.0 ± 0.0
4.598AsnGly: 4.598 ± 2.159
0.0AsnHis: 0.0 ± 0.0
2.299AsnIle: 2.299 ± 1.026
2.299AsnLys: 2.299 ± 1.749
3.448AsnLeu: 3.448 ± 0.34
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
4.598AsnPro: 4.598 ± 0.842
1.149AsnGln: 1.149 ± 0.827
1.149AsnArg: 1.149 ± 0.875
2.299AsnSer: 2.299 ± 1.749
1.149AsnThr: 1.149 ± 0.875
2.299AsnVal: 2.299 ± 1.749
0.0AsnTrp: 0.0 ± 0.0
3.448AsnTyr: 3.448 ± 1.554
0.0AsnXaa: 0.0 ± 0.0
Pro
1.149ProAla: 1.149 ± 0.827
0.0ProCys: 0.0 ± 0.0
2.299ProAsp: 2.299 ± 1.026
4.598ProGlu: 4.598 ± 2.052
0.0ProPhe: 0.0 ± 0.0
2.299ProGly: 2.299 ± 1.026
2.299ProHis: 2.299 ± 1.026
5.747ProIle: 5.747 ± 1.254
0.0ProLys: 0.0 ± 0.0
3.448ProLeu: 3.448 ± 1.629
2.299ProMet: 2.299 ± 0.693
4.598ProAsn: 4.598 ± 0.713
0.0ProPro: 0.0 ± 0.0
1.149ProGln: 1.149 ± 1.029
3.448ProArg: 3.448 ± 1.554
2.299ProSer: 2.299 ± 1.749
3.448ProThr: 3.448 ± 0.34
0.0ProVal: 0.0 ± 0.0
1.149ProTrp: 1.149 ± 0.875
4.598ProTyr: 4.598 ± 2.052
0.0ProXaa: 0.0 ± 0.0
Gln
1.149GlnAla: 1.149 ± 0.875
0.0GlnCys: 0.0 ± 0.0
2.299GlnAsp: 2.299 ± 1.654
0.0GlnGlu: 0.0 ± 0.0
3.448GlnPhe: 3.448 ± 1.554
3.448GlnGly: 3.448 ± 1.629
1.149GlnHis: 1.149 ± 0.827
1.149GlnIle: 1.149 ± 0.827
0.0GlnLys: 0.0 ± 0.0
4.598GlnLeu: 4.598 ± 2.052
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
2.299GlnGln: 2.299 ± 1.026
1.149GlnArg: 1.149 ± 0.875
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
0.0GlnVal: 0.0 ± 0.0
2.299GlnTrp: 2.299 ± 1.026
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.747ArgAla: 5.747 ± 1.506
0.0ArgCys: 0.0 ± 0.0
3.448ArgAsp: 3.448 ± 0.34
6.897ArgGlu: 6.897 ± 3.078
4.598ArgPhe: 4.598 ± 0.713
6.897ArgGly: 6.897 ± 2.547
0.0ArgHis: 0.0 ± 0.0
3.448ArgIle: 3.448 ± 0.34
2.299ArgLys: 2.299 ± 1.749
5.747ArgLeu: 5.747 ± 0.364
3.448ArgMet: 3.448 ± 1.645
1.149ArgAsn: 1.149 ± 0.875
4.598ArgPro: 4.598 ± 0.713
2.299ArgGln: 2.299 ± 1.026
12.644ArgArg: 12.644 ± 1.753
8.046ArgSer: 8.046 ± 0.941
10.345ArgThr: 10.345 ± 1.761
6.897ArgVal: 6.897 ± 0.68
0.0ArgTrp: 0.0 ± 0.0
4.598ArgTyr: 4.598 ± 2.397
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
2.299SerAsp: 2.299 ± 1.026
0.0SerGlu: 0.0 ± 0.0
2.299SerPhe: 2.299 ± 1.026
6.897SerGly: 6.897 ± 4.064
0.0SerHis: 0.0 ± 0.0
1.149SerIle: 1.149 ± 0.875
2.299SerLys: 2.299 ± 1.026
1.149SerLeu: 1.149 ± 0.827
2.299SerMet: 2.299 ± 1.749
5.747SerAsn: 5.747 ± 1.683
3.448SerPro: 3.448 ± 0.34
2.299SerGln: 2.299 ± 1.749
10.345SerArg: 10.345 ± 3.732
2.299SerSer: 2.299 ± 1.749
8.046SerThr: 8.046 ± 1.993
4.598SerVal: 4.598 ± 2.159
0.0SerTrp: 0.0 ± 0.0
2.299SerTyr: 2.299 ± 1.026
0.0SerXaa: 0.0 ± 0.0
Thr
4.598ThrAla: 4.598 ± 3.499
0.0ThrCys: 0.0 ± 0.0
4.598ThrAsp: 4.598 ± 2.159
2.299ThrGlu: 2.299 ± 0.693
3.448ThrPhe: 3.448 ± 0.34
2.299ThrGly: 2.299 ± 1.749
0.0ThrHis: 0.0 ± 0.0
3.448ThrIle: 3.448 ± 1.344
4.598ThrLys: 4.598 ± 0.842
1.149ThrLeu: 1.149 ± 0.875
1.149ThrMet: 1.149 ± 0.842
5.747ThrAsn: 5.747 ± 1.683
6.897ThrPro: 6.897 ± 1.625
2.299ThrGln: 2.299 ± 1.026
5.747ThrArg: 5.747 ± 0.364
8.046ThrSer: 8.046 ± 3.416
6.897ThrThr: 6.897 ± 0.68
5.747ThrVal: 5.747 ± 1.951
2.299ThrTrp: 2.299 ± 1.749
4.598ThrTyr: 4.598 ± 0.842
0.0ThrXaa: 0.0 ± 0.0
Val
2.299ValAla: 2.299 ± 1.026
1.149ValCys: 1.149 ± 0.875
2.299ValAsp: 2.299 ± 1.749
4.598ValGlu: 4.598 ± 0.713
3.448ValPhe: 3.448 ± 1.554
8.046ValGly: 8.046 ± 3.491
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
1.149ValLys: 1.149 ± 0.875
4.598ValLeu: 4.598 ± 0.842
2.299ValMet: 2.299 ± 1.749
2.299ValAsn: 2.299 ± 1.026
2.299ValPro: 2.299 ± 1.026
2.299ValGln: 2.299 ± 0.693
3.448ValArg: 3.448 ± 0.34
1.149ValSer: 1.149 ± 0.875
1.149ValThr: 1.149 ± 0.875
4.598ValVal: 4.598 ± 2.052
3.448ValTrp: 3.448 ± 1.554
1.149ValTyr: 1.149 ± 0.875
0.0ValXaa: 0.0 ± 0.0
Trp
1.149TrpAla: 1.149 ± 0.827
0.0TrpCys: 0.0 ± 0.0
5.747TrpAsp: 5.747 ± 1.506
0.0TrpGlu: 0.0 ± 0.0
1.149TrpPhe: 1.149 ± 0.875
1.149TrpGly: 1.149 ± 0.827
4.598TrpHis: 4.598 ± 0.842
0.0TrpIle: 0.0 ± 0.0
2.299TrpLys: 2.299 ± 1.026
2.299TrpLeu: 2.299 ± 0.693
1.149TrpMet: 1.149 ± 0.827
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.149TrpGln: 1.149 ± 0.875
0.0TrpArg: 0.0 ± 0.0
1.149TrpSer: 1.149 ± 0.875
0.0TrpThr: 0.0 ± 0.0
3.448TrpVal: 3.448 ± 0.34
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
8.046TyrAla: 8.046 ± 0.751
1.149TyrCys: 1.149 ± 0.827
1.149TyrAsp: 1.149 ± 0.875
1.149TyrGlu: 1.149 ± 0.827
1.149TyrPhe: 1.149 ± 0.827
2.299TyrGly: 2.299 ± 1.749
1.149TyrHis: 1.149 ± 0.875
3.448TyrIle: 3.448 ± 1.554
3.448TyrLys: 3.448 ± 1.25
0.0TyrLeu: 0.0 ± 0.0
1.149TyrMet: 1.149 ± 0.875
0.0TyrAsn: 0.0 ± 0.0
2.299TyrPro: 2.299 ± 1.026
0.0TyrGln: 0.0 ± 0.0
6.897TyrArg: 6.897 ± 0.68
3.448TyrSer: 3.448 ± 0.34
1.149TyrThr: 1.149 ± 0.875
3.448TyrVal: 3.448 ± 1.881
1.149TyrTrp: 1.149 ± 0.875
2.299TyrTyr: 2.299 ± 0.693
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (871 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski