Amino acid dipepetide frequency for Basidiobolus meristosporus CBS 931.73

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.28AlaAla: 5.28 ± 0.038
1.022AlaCys: 1.022 ± 0.015
3.185AlaAsp: 3.185 ± 0.024
4.229AlaGlu: 4.229 ± 0.036
2.824AlaPhe: 2.824 ± 0.028
4.122AlaGly: 4.122 ± 0.035
1.512AlaHis: 1.512 ± 0.018
4.3AlaIle: 4.3 ± 0.033
4.224AlaLys: 4.224 ± 0.038
6.772AlaLeu: 6.772 ± 0.043
1.584AlaMet: 1.584 ± 0.017
3.084AlaAsn: 3.084 ± 0.026
3.167AlaPro: 3.167 ± 0.037
2.819AlaGln: 2.819 ± 0.024
3.301AlaArg: 3.301 ± 0.025
5.604AlaSer: 5.604 ± 0.037
4.281AlaThr: 4.281 ± 0.029
4.372AlaVal: 4.372 ± 0.035
0.742AlaTrp: 0.742 ± 0.013
2.168AlaTyr: 2.168 ± 0.022
0.0AlaXaa: 0.0 ± 0.0
Cys
0.896CysAla: 0.896 ± 0.013
0.335CysCys: 0.335 ± 0.011
0.757CysAsp: 0.757 ± 0.013
0.77CysGlu: 0.77 ± 0.013
0.7CysPhe: 0.7 ± 0.015
1.128CysGly: 1.128 ± 0.019
0.386CysHis: 0.386 ± 0.01
0.945CysIle: 0.945 ± 0.015
0.749CysLys: 0.749 ± 0.013
1.486CysLeu: 1.486 ± 0.019
0.362CysMet: 0.362 ± 0.01
0.65CysAsn: 0.65 ± 0.011
0.755CysPro: 0.755 ± 0.018
0.628CysGln: 0.628 ± 0.011
0.718CysArg: 0.718 ± 0.012
1.216CysSer: 1.216 ± 0.016
0.84CysThr: 0.84 ± 0.013
1.024CysVal: 1.024 ± 0.015
0.178CysTrp: 0.178 ± 0.005
0.54CysTyr: 0.54 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
3.335AspAla: 3.335 ± 0.031
0.738AspCys: 0.738 ± 0.01
3.305AspAsp: 3.305 ± 0.042
3.829AspGlu: 3.829 ± 0.037
2.332AspPhe: 2.332 ± 0.022
3.252AspGly: 3.252 ± 0.031
1.221AspHis: 1.221 ± 0.019
3.511AspIle: 3.511 ± 0.026
2.591AspLys: 2.591 ± 0.025
4.906AspLeu: 4.906 ± 0.034
1.237AspMet: 1.237 ± 0.017
2.127AspAsn: 2.127 ± 0.025
2.714AspPro: 2.714 ± 0.025
1.981AspGln: 1.981 ± 0.02
2.423AspArg: 2.423 ± 0.023
4.271AspSer: 4.271 ± 0.033
2.885AspThr: 2.885 ± 0.025
3.304AspVal: 3.304 ± 0.024
0.692AspTrp: 0.692 ± 0.01
1.911AspTyr: 1.911 ± 0.023
0.0AspXaa: 0.0 ± 0.0
Glu
4.695GluAla: 4.695 ± 0.031
0.834GluCys: 0.834 ± 0.014
3.803GluAsp: 3.803 ± 0.033
5.784GluGlu: 5.784 ± 0.053
2.544GluPhe: 2.544 ± 0.023
3.269GluGly: 3.269 ± 0.026
1.537GluHis: 1.537 ± 0.018
3.838GluIle: 3.838 ± 0.029
4.473GluLys: 4.473 ± 0.039
6.033GluLeu: 6.033 ± 0.042
1.56GluMet: 1.56 ± 0.015
3.039GluAsn: 3.039 ± 0.025
2.505GluPro: 2.505 ± 0.029
2.643GluGln: 2.643 ± 0.027
3.29GluArg: 3.29 ± 0.026
4.636GluSer: 4.636 ± 0.04
3.419GluThr: 3.419 ± 0.032
3.906GluVal: 3.906 ± 0.029
0.697GluTrp: 0.697 ± 0.012
2.365GluTyr: 2.365 ± 0.023
0.0GluXaa: 0.0 ± 0.0
Phe
2.824PheAla: 2.824 ± 0.025
0.673PheCys: 0.673 ± 0.011
2.463PheAsp: 2.463 ± 0.02
2.546PheGlu: 2.546 ± 0.02
1.866PhePhe: 1.866 ± 0.023
2.959PheGly: 2.959 ± 0.031
0.965PheHis: 0.965 ± 0.013
2.406PheIle: 2.406 ± 0.024
2.062PheLys: 2.062 ± 0.019
4.024PheLeu: 4.024 ± 0.036
0.931PheMet: 0.931 ± 0.015
1.945PheAsn: 1.945 ± 0.019
1.956PhePro: 1.956 ± 0.02
1.621PheGln: 1.621 ± 0.017
1.903PheArg: 1.903 ± 0.019
3.489PheSer: 3.489 ± 0.027
2.533PheThr: 2.533 ± 0.021
2.844PheVal: 2.844 ± 0.022
0.57PheTrp: 0.57 ± 0.011
1.462PheTyr: 1.462 ± 0.017
0.0PheXaa: 0.0 ± 0.0
Gly
4.07GlyAla: 4.07 ± 0.036
1.035GlyCys: 1.035 ± 0.016
3.174GlyAsp: 3.174 ± 0.034
3.421GlyGlu: 3.421 ± 0.033
2.814GlyPhe: 2.814 ± 0.026
5.322GlyGly: 5.322 ± 0.166
1.541GlyHis: 1.541 ± 0.021
3.768GlyIle: 3.768 ± 0.028
3.732GlyLys: 3.732 ± 0.043
5.419GlyLeu: 5.419 ± 0.035
1.305GlyMet: 1.305 ± 0.018
3.006GlyAsn: 3.006 ± 0.054
2.261GlyPro: 2.261 ± 0.029
2.184GlyGln: 2.184 ± 0.023
3.103GlyArg: 3.103 ± 0.033
4.993GlySer: 4.993 ± 0.052
3.252GlyThr: 3.252 ± 0.03
4.21GlyVal: 4.21 ± 0.038
0.863GlyTrp: 0.863 ± 0.016
2.548GlyTyr: 2.548 ± 0.031
0.0GlyXaa: 0.0 ± 0.0
His
1.36HisAla: 1.36 ± 0.016
0.418HisCys: 0.418 ± 0.008
1.133HisAsp: 1.133 ± 0.014
1.383HisGlu: 1.383 ± 0.015
1.066HisPhe: 1.066 ± 0.014
1.551HisGly: 1.551 ± 0.02
0.834HisHis: 0.834 ± 0.017
1.42HisIle: 1.42 ± 0.018
1.184HisLys: 1.184 ± 0.019
2.321HisLeu: 2.321 ± 0.02
0.563HisMet: 0.563 ± 0.01
0.969HisAsn: 0.969 ± 0.014
1.506HisPro: 1.506 ± 0.017
1.053HisGln: 1.053 ± 0.014
1.347HisArg: 1.347 ± 0.015
2.083HisSer: 2.083 ± 0.023
1.351HisThr: 1.351 ± 0.017
1.404HisVal: 1.404 ± 0.016
0.297HisTrp: 0.297 ± 0.006
0.79HisTyr: 0.79 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.179IleAla: 4.179 ± 0.026
0.988IleCys: 0.988 ± 0.014
3.161IleAsp: 3.161 ± 0.03
3.519IleGlu: 3.519 ± 0.03
2.54IlePhe: 2.54 ± 0.024
3.536IleGly: 3.536 ± 0.031
1.586IleHis: 1.586 ± 0.018
3.31IleIle: 3.31 ± 0.03
3.095IleLys: 3.095 ± 0.026
5.745IleLeu: 5.745 ± 0.041
1.211IleMet: 1.211 ± 0.017
2.536IleAsn: 2.536 ± 0.023
3.331IlePro: 3.331 ± 0.026
2.472IleGln: 2.472 ± 0.022
3.066IleArg: 3.066 ± 0.023
4.786IleSer: 4.786 ± 0.032
3.38IleThr: 3.38 ± 0.024
3.85IleVal: 3.85 ± 0.029
0.696IleTrp: 0.696 ± 0.011
1.876IleTyr: 1.876 ± 0.02
0.0IleXaa: 0.0 ± 0.0
Lys
4.185LysAla: 4.185 ± 0.033
0.845LysCys: 0.845 ± 0.017
2.96LysAsp: 2.96 ± 0.029
4.148LysGlu: 4.148 ± 0.037
2.053LysPhe: 2.053 ± 0.018
3.036LysGly: 3.036 ± 0.034
1.401LysHis: 1.401 ± 0.017
3.337LysIle: 3.337 ± 0.029
4.329LysLys: 4.329 ± 0.049
5.459LysLeu: 5.459 ± 0.04
1.215LysMet: 1.215 ± 0.016
2.679LysAsn: 2.679 ± 0.022
3.048LysPro: 3.048 ± 0.035
2.361LysGln: 2.361 ± 0.021
3.402LysArg: 3.402 ± 0.029
4.455LysSer: 4.455 ± 0.043
3.105LysThr: 3.105 ± 0.024
3.686LysVal: 3.686 ± 0.029
0.69LysTrp: 0.69 ± 0.012
2.182LysTyr: 2.182 ± 0.021
0.0LysXaa: 0.0 ± 0.0
Leu
6.82LeuAla: 6.82 ± 0.046
1.509LeuCys: 1.509 ± 0.016
5.061LeuAsp: 5.061 ± 0.032
6.096LeuGlu: 6.096 ± 0.036
3.956LeuPhe: 3.956 ± 0.031
5.719LeuGly: 5.719 ± 0.038
2.173LeuHis: 2.173 ± 0.022
5.103LeuIle: 5.103 ± 0.045
5.566LeuLys: 5.566 ± 0.037
9.114LeuLeu: 9.114 ± 0.068
2.069LeuMet: 2.069 ± 0.02
4.3LeuAsn: 4.3 ± 0.03
4.869LeuPro: 4.869 ± 0.035
3.785LeuGln: 3.785 ± 0.03
5.027LeuArg: 5.027 ± 0.032
7.69LeuSer: 7.69 ± 0.042
5.337LeuThr: 5.337 ± 0.037
5.951LeuVal: 5.951 ± 0.036
1.046LeuTrp: 1.046 ± 0.015
2.9LeuTyr: 2.9 ± 0.025
0.0LeuXaa: 0.0 ± 0.0
Met
1.737MetAla: 1.737 ± 0.015
0.31MetCys: 0.31 ± 0.007
1.292MetAsp: 1.292 ± 0.016
1.49MetGlu: 1.49 ± 0.017
0.918MetPhe: 0.918 ± 0.012
1.274MetGly: 1.274 ± 0.015
0.429MetHis: 0.429 ± 0.009
1.294MetIle: 1.294 ± 0.016
1.344MetLys: 1.344 ± 0.016
2.04MetLeu: 2.04 ± 0.019
0.59MetMet: 0.59 ± 0.011
1.112MetAsn: 1.112 ± 0.015
0.937MetPro: 0.937 ± 0.016
0.798MetGln: 0.798 ± 0.011
1.039MetArg: 1.039 ± 0.014
1.886MetSer: 1.886 ± 0.02
1.247MetThr: 1.247 ± 0.015
1.533MetVal: 1.533 ± 0.018
0.225MetTrp: 0.225 ± 0.007
0.71MetTyr: 0.71 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.036AsnAla: 3.036 ± 0.024
0.676AsnCys: 0.676 ± 0.013
2.223AsnAsp: 2.223 ± 0.023
2.75AsnGlu: 2.75 ± 0.023
1.781AsnPhe: 1.781 ± 0.018
3.271AsnGly: 3.271 ± 0.057
1.081AsnHis: 1.081 ± 0.015
2.831AsnIle: 2.831 ± 0.023
2.252AsnLys: 2.252 ± 0.024
4.21AsnLeu: 4.21 ± 0.028
1.087AsnMet: 1.087 ± 0.015
2.022AsnAsn: 2.022 ± 0.024
2.882AsnPro: 2.882 ± 0.023
1.941AsnGln: 1.941 ± 0.023
2.17AsnArg: 2.17 ± 0.021
3.689AsnSer: 3.689 ± 0.032
2.751AsnThr: 2.751 ± 0.031
2.853AsnVal: 2.853 ± 0.023
0.568AsnTrp: 0.568 ± 0.011
1.504AsnTyr: 1.504 ± 0.017
0.0AsnXaa: 0.0 ± 0.0
Pro
3.368ProAla: 3.368 ± 0.029
0.59ProCys: 0.59 ± 0.011
2.579ProAsp: 2.579 ± 0.026
3.703ProGlu: 3.703 ± 0.036
2.007ProPhe: 2.007 ± 0.023
2.84ProGly: 2.84 ± 0.035
1.136ProHis: 1.136 ± 0.016
2.71ProIle: 2.71 ± 0.024
2.934ProLys: 2.934 ± 0.026
4.266ProLeu: 4.266 ± 0.034
0.991ProMet: 0.991 ± 0.015
2.555ProAsn: 2.555 ± 0.024
3.091ProPro: 3.091 ± 0.056
1.944ProGln: 1.944 ± 0.022
2.275ProArg: 2.275 ± 0.026
4.797ProSer: 4.797 ± 0.049
3.631ProThr: 3.631 ± 0.039
3.215ProVal: 3.215 ± 0.03
0.502ProTrp: 0.502 ± 0.009
1.622ProTyr: 1.622 ± 0.017
0.0ProXaa: 0.0 ± 0.0
Gln
2.913GlnAla: 2.913 ± 0.025
0.589GlnCys: 0.589 ± 0.011
1.915GlnAsp: 1.915 ± 0.019
2.8GlnGlu: 2.8 ± 0.027
1.596GlnPhe: 1.596 ± 0.017
2.03GlnGly: 2.03 ± 0.021
0.999GlnHis: 0.999 ± 0.013
2.268GlnIle: 2.268 ± 0.02
2.382GlnLys: 2.382 ± 0.021
3.926GlnLeu: 3.926 ± 0.031
0.974GlnMet: 0.974 ± 0.014
1.78GlnAsn: 1.78 ± 0.021
2.166GlnPro: 2.166 ± 0.027
2.085GlnGln: 2.085 ± 0.035
2.094GlnArg: 2.094 ± 0.024
2.969GlnSer: 2.969 ± 0.024
2.149GlnThr: 2.149 ± 0.021
2.583GlnVal: 2.583 ± 0.022
0.478GlnTrp: 0.478 ± 0.009
1.436GlnTyr: 1.436 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
3.18ArgAla: 3.18 ± 0.025
0.715ArgCys: 0.715 ± 0.013
2.457ArgAsp: 2.457 ± 0.021
3.222ArgGlu: 3.222 ± 0.026
2.195ArgPhe: 2.195 ± 0.022
2.882ArgGly: 2.882 ± 0.029
1.291ArgHis: 1.291 ± 0.016
3.05ArgIle: 3.05 ± 0.026
3.543ArgLys: 3.543 ± 0.032
4.673ArgLeu: 4.673 ± 0.033
1.193ArgMet: 1.193 ± 0.014
2.403ArgAsn: 2.403 ± 0.023
2.177ArgPro: 2.177 ± 0.022
2.062ArgGln: 2.062 ± 0.022
3.471ArgArg: 3.471 ± 0.034
3.905ArgSer: 3.905 ± 0.035
2.627ArgThr: 2.627 ± 0.022
3.122ArgVal: 3.122 ± 0.025
0.651ArgTrp: 0.651 ± 0.011
1.882ArgTyr: 1.882 ± 0.023
0.0ArgXaa: 0.0 ± 0.0
Ser
5.289SerAla: 5.289 ± 0.036
1.109SerCys: 1.109 ± 0.016
4.06SerAsp: 4.06 ± 0.028
4.876SerGlu: 4.876 ± 0.032
3.385SerPhe: 3.385 ± 0.025
5.188SerGly: 5.188 ± 0.049
1.938SerHis: 1.938 ± 0.019
4.8SerIle: 4.8 ± 0.031
4.699SerLys: 4.699 ± 0.041
7.74SerLeu: 7.74 ± 0.045
1.722SerMet: 1.722 ± 0.017
3.819SerAsn: 3.819 ± 0.034
4.555SerPro: 4.555 ± 0.043
3.266SerGln: 3.266 ± 0.027
3.981SerArg: 3.981 ± 0.035
7.798SerSer: 7.798 ± 0.07
5.273SerThr: 5.273 ± 0.052
4.834SerVal: 4.834 ± 0.031
0.984SerTrp: 0.984 ± 0.014
2.496SerTyr: 2.496 ± 0.024
0.0SerXaa: 0.0 ± 0.0
Thr
3.879ThrAla: 3.879 ± 0.029
0.838ThrCys: 0.838 ± 0.015
2.594ThrAsp: 2.594 ± 0.024
3.423ThrGlu: 3.423 ± 0.038
2.492ThrPhe: 2.492 ± 0.026
3.593ThrGly: 3.593 ± 0.031
1.405ThrHis: 1.405 ± 0.018
3.503ThrIle: 3.503 ± 0.028
3.219ThrLys: 3.219 ± 0.025
5.64ThrLeu: 5.64 ± 0.035
1.138ThrMet: 1.138 ± 0.015
2.544ThrAsn: 2.544 ± 0.024
3.648ThrPro: 3.648 ± 0.034
2.204ThrGln: 2.204 ± 0.024
2.741ThrArg: 2.741 ± 0.023
5.117ThrSer: 5.117 ± 0.045
3.916ThrThr: 3.916 ± 0.052
3.736ThrVal: 3.736 ± 0.03
0.697ThrTrp: 0.697 ± 0.011
1.907ThrTyr: 1.907 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
4.781ValAla: 4.781 ± 0.032
1.005ValCys: 1.005 ± 0.017
3.738ValAsp: 3.738 ± 0.031
4.235ValGlu: 4.235 ± 0.034
2.78ValPhe: 2.78 ± 0.025
3.862ValGly: 3.862 ± 0.033
1.435ValHis: 1.435 ± 0.017
3.796ValIle: 3.796 ± 0.029
3.698ValLys: 3.698 ± 0.035
5.865ValLeu: 5.865 ± 0.041
1.383ValMet: 1.383 ± 0.017
2.862ValAsn: 2.862 ± 0.023
3.084ValPro: 3.084 ± 0.029
2.416ValGln: 2.416 ± 0.023
2.947ValArg: 2.947 ± 0.023
4.782ValSer: 4.782 ± 0.028
3.676ValThr: 3.676 ± 0.029
4.585ValVal: 4.585 ± 0.04
0.741ValTrp: 0.741 ± 0.012
2.111ValTyr: 2.111 ± 0.021
0.0ValXaa: 0.0 ± 0.0
Trp
0.716TrpAla: 0.716 ± 0.011
0.221TrpCys: 0.221 ± 0.006
0.715TrpAsp: 0.715 ± 0.013
0.689TrpGlu: 0.689 ± 0.011
0.566TrpPhe: 0.566 ± 0.012
0.74TrpGly: 0.74 ± 0.014
0.264TrpHis: 0.264 ± 0.008
0.774TrpIle: 0.774 ± 0.013
0.774TrpLys: 0.774 ± 0.012
1.121TrpLeu: 1.121 ± 0.015
0.318TrpMet: 0.318 ± 0.007
0.615TrpAsn: 0.615 ± 0.011
0.398TrpPro: 0.398 ± 0.008
0.399TrpGln: 0.399 ± 0.009
0.666TrpArg: 0.666 ± 0.011
0.995TrpSer: 0.995 ± 0.016
0.664TrpThr: 0.664 ± 0.009
0.748TrpVal: 0.748 ± 0.012
0.221TrpTrp: 0.221 ± 0.006
0.405TrpTyr: 0.405 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.049TyrAla: 2.049 ± 0.021
0.614TyrCys: 0.614 ± 0.011
1.989TyrAsp: 1.989 ± 0.025
1.956TyrGlu: 1.956 ± 0.022
1.629TyrPhe: 1.629 ± 0.018
2.448TyrGly: 2.448 ± 0.036
0.901TyrHis: 0.901 ± 0.013
1.898TyrIle: 1.898 ± 0.017
1.73TyrLys: 1.73 ± 0.022
3.331TyrLeu: 3.331 ± 0.027
0.77TyrMet: 0.77 ± 0.012
1.53TyrAsn: 1.53 ± 0.016
1.703TyrPro: 1.703 ± 0.022
1.471TyrGln: 1.471 ± 0.017
1.736TyrArg: 1.736 ± 0.019
2.649TyrSer: 2.649 ± 0.023
1.921TyrThr: 1.921 ± 0.021
2.019TyrVal: 2.019 ± 0.02
0.471TyrTrp: 0.471 ± 0.009
1.254TyrTyr: 1.254 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 15513 proteins (5895669 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski