Amino acid dipepetide frequency for Ailuropoda melanoleuca papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.529AlaAla: 4.529 ± 1.688
0.906AlaCys: 0.906 ± 0.655
4.529AlaAsp: 4.529 ± 1.087
3.623AlaGlu: 3.623 ± 0.781
3.17AlaPhe: 3.17 ± 1.717
2.717AlaGly: 2.717 ± 1.13
1.359AlaHis: 1.359 ± 0.876
2.264AlaIle: 2.264 ± 0.935
4.529AlaLys: 4.529 ± 0.626
4.076AlaLeu: 4.076 ± 1.234
2.264AlaMet: 2.264 ± 0.888
2.264AlaAsn: 2.264 ± 1.046
3.17AlaPro: 3.17 ± 0.914
2.264AlaGln: 2.264 ± 0.912
2.717AlaArg: 2.717 ± 0.896
5.435AlaSer: 5.435 ± 1.82
4.076AlaThr: 4.076 ± 1.465
2.264AlaVal: 2.264 ± 0.915
0.0AlaTrp: 0.0 ± 0.0
1.812AlaTyr: 1.812 ± 1.011
0.0AlaXaa: 0.0 ± 0.0
Cys
1.812CysAla: 1.812 ± 0.633
0.0CysCys: 0.0 ± 0.0
1.359CysAsp: 1.359 ± 0.451
1.359CysGlu: 1.359 ± 0.788
0.906CysPhe: 0.906 ± 0.473
2.717CysGly: 2.717 ± 2.748
0.0CysHis: 0.0 ± 0.0
0.906CysIle: 0.906 ± 0.655
1.812CysLys: 1.812 ± 1.033
1.812CysLeu: 1.812 ± 1.293
0.453CysMet: 0.453 ± 0.372
0.453CysAsn: 0.453 ± 0.395
1.812CysPro: 1.812 ± 0.777
0.453CysGln: 0.453 ± 0.372
1.359CysArg: 1.359 ± 1.117
2.264CysSer: 2.264 ± 1.316
1.359CysThr: 1.359 ± 0.69
1.812CysVal: 1.812 ± 0.765
1.359CysTrp: 1.359 ± 0.451
0.906CysTyr: 0.906 ± 1.316
0.0CysXaa: 0.0 ± 0.0
Asp
2.717AspAla: 2.717 ± 0.492
1.812AspCys: 1.812 ± 0.765
2.717AspAsp: 2.717 ± 1.275
3.623AspGlu: 3.623 ± 1.266
4.982AspPhe: 4.982 ± 1.386
4.529AspGly: 4.529 ± 1.687
1.359AspHis: 1.359 ± 0.394
3.623AspIle: 3.623 ± 1.239
2.264AspLys: 2.264 ± 1.211
6.341AspLeu: 6.341 ± 2.962
0.453AspMet: 0.453 ± 0.466
2.717AspAsn: 2.717 ± 1.686
2.717AspPro: 2.717 ± 1.135
1.359AspGln: 1.359 ± 0.861
1.359AspArg: 1.359 ± 0.717
6.793AspSer: 6.793 ± 1.901
1.812AspThr: 1.812 ± 1.357
3.623AspVal: 3.623 ± 1.443
0.453AspTrp: 0.453 ± 0.372
0.906AspTyr: 0.906 ± 0.782
0.0AspXaa: 0.0 ± 0.0
Glu
1.812GluAla: 1.812 ± 1.489
0.453GluCys: 0.453 ± 0.372
4.982GluAsp: 4.982 ± 1.069
8.152GluGlu: 8.152 ± 2.922
1.359GluPhe: 1.359 ± 0.758
4.529GluGly: 4.529 ± 1.785
2.264GluHis: 2.264 ± 0.375
1.359GluIle: 1.359 ± 0.861
4.076GluLys: 4.076 ± 1.524
4.982GluLeu: 4.982 ± 1.913
0.906GluMet: 0.906 ± 0.456
2.264GluAsn: 2.264 ± 1.358
1.812GluPro: 1.812 ± 0.713
6.793GluGln: 6.793 ± 2.964
2.264GluArg: 2.264 ± 0.935
1.359GluSer: 1.359 ± 0.454
4.076GluThr: 4.076 ± 0.87
2.264GluVal: 2.264 ± 0.508
0.453GluTrp: 0.453 ± 0.372
3.623GluTyr: 3.623 ± 1.415
0.0GluXaa: 0.0 ± 0.0
Phe
2.264PheAla: 2.264 ± 1.064
1.359PheCys: 1.359 ± 0.717
4.529PheAsp: 4.529 ± 1.756
0.906PheGlu: 0.906 ± 0.5
3.623PhePhe: 3.623 ± 1.117
4.529PheGly: 4.529 ± 0.799
0.906PheHis: 0.906 ± 0.5
2.264PheIle: 2.264 ± 0.886
2.717PheLys: 2.717 ± 0.997
3.17PheLeu: 3.17 ± 1.359
1.812PheMet: 1.812 ± 0.912
1.359PheAsn: 1.359 ± 1.397
2.264PhePro: 2.264 ± 0.522
1.812PheGln: 1.812 ± 0.986
0.906PheArg: 0.906 ± 0.456
4.076PheSer: 4.076 ± 2.509
1.359PheThr: 1.359 ± 1.117
1.359PheVal: 1.359 ± 0.876
0.906PheTrp: 0.906 ± 0.456
1.359PheTyr: 1.359 ± 0.843
0.0PheXaa: 0.0 ± 0.0
Gly
3.623GlyAla: 3.623 ± 1.136
2.264GlyCys: 2.264 ± 1.557
3.17GlyAsp: 3.17 ± 1.039
6.341GlyGlu: 6.341 ± 1.352
0.906GlyPhe: 0.906 ± 0.456
4.529GlyGly: 4.529 ± 2.482
0.906GlyHis: 0.906 ± 0.931
5.435GlyIle: 5.435 ± 2.297
4.529GlyLys: 4.529 ± 2.043
4.076GlyLeu: 4.076 ± 1.463
1.359GlyMet: 1.359 ± 0.468
3.17GlyAsn: 3.17 ± 0.757
1.359GlyPro: 1.359 ± 0.717
1.359GlyGln: 1.359 ± 0.814
3.623GlyArg: 3.623 ± 0.841
7.699GlySer: 7.699 ± 2.454
4.076GlyThr: 4.076 ± 2.461
5.435GlyVal: 5.435 ± 2.346
0.0GlyTrp: 0.0 ± 0.0
2.717GlyTyr: 2.717 ± 1.879
0.0GlyXaa: 0.0 ± 0.0
His
1.359HisAla: 1.359 ± 0.451
0.906HisCys: 0.906 ± 0.768
0.453HisAsp: 0.453 ± 0.372
0.453HisGlu: 0.453 ± 0.372
1.812HisPhe: 1.812 ± 0.615
0.0HisGly: 0.0 ± 0.0
0.453HisHis: 0.453 ± 0.451
1.812HisIle: 1.812 ± 1.085
0.0HisLys: 0.0 ± 0.0
0.906HisLeu: 0.906 ± 0.768
0.0HisMet: 0.0 ± 0.0
0.906HisAsn: 0.906 ± 0.533
1.812HisPro: 1.812 ± 1.245
0.0HisGln: 0.0 ± 0.0
0.906HisArg: 0.906 ± 0.5
2.717HisSer: 2.717 ± 1.224
1.812HisThr: 1.812 ± 1.245
1.359HisVal: 1.359 ± 0.754
0.453HisTrp: 0.453 ± 0.466
0.906HisTyr: 0.906 ± 0.456
0.0HisXaa: 0.0 ± 0.0
Ile
2.717IleAla: 2.717 ± 1.197
0.906IleCys: 0.906 ± 0.782
3.17IleAsp: 3.17 ± 1.143
1.812IleGlu: 1.812 ± 0.912
2.717IlePhe: 2.717 ± 1.032
2.264IleGly: 2.264 ± 1.675
0.0IleHis: 0.0 ± 0.0
0.453IleIle: 0.453 ± 0.451
1.812IleLys: 1.812 ± 0.633
3.17IleLeu: 3.17 ± 1.528
0.906IleMet: 0.906 ± 0.7
1.359IleAsn: 1.359 ± 0.454
2.264IlePro: 2.264 ± 1.126
2.717IleGln: 2.717 ± 0.91
1.812IleArg: 1.812 ± 1.301
2.264IleSer: 2.264 ± 0.533
5.435IleThr: 5.435 ± 1.619
1.812IleVal: 1.812 ± 0.713
0.453IleTrp: 0.453 ± 0.658
0.906IleTyr: 0.906 ± 0.493
0.0IleXaa: 0.0 ± 0.0
Lys
4.982LysAla: 4.982 ± 1.327
1.359LysCys: 1.359 ± 0.717
1.812LysAsp: 1.812 ± 0.847
3.623LysGlu: 3.623 ± 1.488
3.17LysPhe: 3.17 ± 1.243
4.076LysGly: 4.076 ± 1.826
1.812LysHis: 1.812 ± 1.091
1.359LysIle: 1.359 ± 0.92
3.17LysLys: 3.17 ± 1.224
4.076LysLeu: 4.076 ± 1.907
2.264LysMet: 2.264 ± 0.798
1.359LysAsn: 1.359 ± 0.754
2.264LysPro: 2.264 ± 0.874
2.264LysGln: 2.264 ± 0.882
6.341LysArg: 6.341 ± 0.629
4.076LysSer: 4.076 ± 1.375
1.812LysThr: 1.812 ± 1.085
4.982LysVal: 4.982 ± 1.529
1.812LysTrp: 1.812 ± 0.687
2.717LysTyr: 2.717 ± 0.511
0.0LysXaa: 0.0 ± 0.0
Leu
2.717LeuAla: 2.717 ± 1.232
1.359LeuCys: 1.359 ± 0.838
3.623LeuAsp: 3.623 ± 0.615
4.529LeuGlu: 4.529 ± 1.403
2.264LeuPhe: 2.264 ± 1.273
6.341LeuGly: 6.341 ± 1.061
1.812LeuHis: 1.812 ± 1.28
2.264LeuIle: 2.264 ± 0.826
4.982LeuLys: 4.982 ± 1.822
9.058LeuLeu: 9.058 ± 3.72
2.264LeuMet: 2.264 ± 1.255
0.906LeuAsn: 0.906 ± 0.655
7.699LeuPro: 7.699 ± 1.693
5.435LeuGln: 5.435 ± 0.979
2.264LeuArg: 2.264 ± 0.887
9.058LeuSer: 9.058 ± 1.03
4.076LeuThr: 4.076 ± 1.481
3.623LeuVal: 3.623 ± 1.199
1.359LeuTrp: 1.359 ± 0.454
4.076LeuTyr: 4.076 ± 2.327
0.0LeuXaa: 0.0 ± 0.0
Met
1.359MetAla: 1.359 ± 0.861
1.812MetCys: 1.812 ± 0.675
0.906MetAsp: 0.906 ± 0.782
1.359MetGlu: 1.359 ± 0.788
0.906MetPhe: 0.906 ± 0.931
0.906MetGly: 0.906 ± 0.456
0.906MetHis: 0.906 ± 0.493
0.0MetIle: 0.0 ± 0.0
0.453MetLys: 0.453 ± 0.372
1.812MetLeu: 1.812 ± 1.011
0.453MetMet: 0.453 ± 0.395
0.906MetAsn: 0.906 ± 0.456
0.0MetPro: 0.0 ± 0.0
1.359MetGln: 1.359 ± 0.69
1.812MetArg: 1.812 ± 0.715
0.906MetSer: 0.906 ± 0.745
0.0MetThr: 0.0 ± 0.0
2.264MetVal: 2.264 ± 0.642
0.0MetTrp: 0.0 ± 0.0
0.453MetTyr: 0.453 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
3.623AsnAla: 3.623 ± 0.995
1.359AsnCys: 1.359 ± 0.754
0.906AsnAsp: 0.906 ± 0.655
2.264AsnGlu: 2.264 ± 0.935
1.812AsnPhe: 1.812 ± 0.576
1.359AsnGly: 1.359 ± 0.69
0.453AsnHis: 0.453 ± 0.451
1.359AsnIle: 1.359 ± 0.394
1.812AsnLys: 1.812 ± 1.289
1.359AsnLeu: 1.359 ± 0.861
0.0AsnMet: 0.0 ± 0.0
1.812AsnAsn: 1.812 ± 1.357
3.623AsnPro: 3.623 ± 1.352
1.812AsnGln: 1.812 ± 1.357
1.812AsnArg: 1.812 ± 1.357
3.17AsnSer: 3.17 ± 1.139
3.17AsnThr: 3.17 ± 0.691
2.264AsnVal: 2.264 ± 0.375
1.359AsnTrp: 1.359 ± 0.451
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.623ProAla: 3.623 ± 1.239
1.359ProCys: 1.359 ± 0.824
5.888ProAsp: 5.888 ± 3.292
1.812ProGlu: 1.812 ± 0.788
3.623ProPhe: 3.623 ± 0.716
1.359ProGly: 1.359 ± 0.451
0.0ProHis: 0.0 ± 0.0
3.623ProIle: 3.623 ± 0.781
5.888ProLys: 5.888 ± 1.15
7.699ProLeu: 7.699 ± 2.277
0.453ProMet: 0.453 ± 0.372
2.264ProAsn: 2.264 ± 0.723
6.341ProPro: 6.341 ± 1.173
2.717ProGln: 2.717 ± 1.625
2.717ProArg: 2.717 ± 0.855
4.529ProSer: 4.529 ± 1.242
4.076ProThr: 4.076 ± 1.735
3.17ProVal: 3.17 ± 0.936
0.906ProTrp: 0.906 ± 0.493
1.812ProTyr: 1.812 ± 1.066
0.0ProXaa: 0.0 ± 0.0
Gln
2.717GlnAla: 2.717 ± 0.936
0.906GlnCys: 0.906 ± 0.473
1.812GlnAsp: 1.812 ± 0.615
3.623GlnGlu: 3.623 ± 2.306
0.0GlnPhe: 0.0 ± 0.0
2.717GlnGly: 2.717 ± 1.39
0.453GlnHis: 0.453 ± 0.395
1.812GlnIle: 1.812 ± 0.713
1.359GlnLys: 1.359 ± 0.454
4.529GlnLeu: 4.529 ± 0.72
0.453GlnMet: 0.453 ± 0.466
1.812GlnAsn: 1.812 ± 1.863
3.623GlnPro: 3.623 ± 1.199
15.851GlnGln: 15.851 ± 11.247
2.717GlnArg: 2.717 ± 0.936
2.717GlnSer: 2.717 ± 0.787
3.17GlnThr: 3.17 ± 1.06
5.435GlnVal: 5.435 ± 1.448
1.359GlnTrp: 1.359 ± 0.754
2.717GlnTyr: 2.717 ± 1.657
0.0GlnXaa: 0.0 ± 0.0
Arg
3.623ArgAla: 3.623 ± 1.019
1.359ArgCys: 1.359 ± 0.678
1.359ArgAsp: 1.359 ± 0.678
0.906ArgGlu: 0.906 ± 0.79
1.812ArgPhe: 1.812 ± 0.731
4.076ArgGly: 4.076 ± 2.306
2.264ArgHis: 2.264 ± 0.912
1.359ArgIle: 1.359 ± 0.876
5.888ArgLys: 5.888 ± 0.987
6.341ArgLeu: 6.341 ± 0.629
0.453ArgMet: 0.453 ± 0.434
1.359ArgAsn: 1.359 ± 0.754
3.623ArgPro: 3.623 ± 1.849
3.17ArgGln: 3.17 ± 0.833
3.17ArgArg: 3.17 ± 1.311
2.717ArgSer: 2.717 ± 1.071
1.812ArgThr: 1.812 ± 0.788
3.17ArgVal: 3.17 ± 1.183
0.0ArgTrp: 0.0 ± 0.0
2.264ArgTyr: 2.264 ± 0.882
0.0ArgXaa: 0.0 ± 0.0
Ser
5.435SerAla: 5.435 ± 1.404
0.906SerCys: 0.906 ± 0.768
4.982SerAsp: 4.982 ± 1.817
4.982SerGlu: 4.982 ± 0.867
2.717SerPhe: 2.717 ± 1.753
7.699SerGly: 7.699 ± 1.772
1.359SerHis: 1.359 ± 0.876
2.717SerIle: 2.717 ± 2.181
4.529SerLys: 4.529 ± 2.55
5.888SerLeu: 5.888 ± 0.83
0.906SerMet: 0.906 ± 0.5
2.717SerAsn: 2.717 ± 1.625
6.341SerPro: 6.341 ± 2.029
2.717SerGln: 2.717 ± 0.903
4.982SerArg: 4.982 ± 1.729
15.399SerSer: 15.399 ± 6.102
6.341SerThr: 6.341 ± 2.103
6.793SerVal: 6.793 ± 2.066
0.453SerTrp: 0.453 ± 0.372
0.906SerTyr: 0.906 ± 0.473
0.0SerXaa: 0.0 ± 0.0
Thr
3.623ThrAla: 3.623 ± 0.996
2.264ThrCys: 2.264 ± 0.885
2.717ThrAsp: 2.717 ± 1.169
4.076ThrGlu: 4.076 ± 1.448
2.717ThrPhe: 2.717 ± 0.935
4.529ThrGly: 4.529 ± 0.85
1.359ThrHis: 1.359 ± 0.876
1.812ThrIle: 1.812 ± 0.713
0.906ThrLys: 0.906 ± 0.493
3.17ThrLeu: 3.17 ± 1.133
0.906ThrMet: 0.906 ± 0.533
4.076ThrAsn: 4.076 ± 1.428
3.623ThrPro: 3.623 ± 1.598
2.264ThrGln: 2.264 ± 0.375
4.076ThrArg: 4.076 ± 1.849
5.888ThrSer: 5.888 ± 0.914
4.982ThrThr: 4.982 ± 1.863
4.529ThrVal: 4.529 ± 1.043
0.453ThrTrp: 0.453 ± 0.395
2.717ThrTyr: 2.717 ± 0.787
0.0ThrXaa: 0.0 ± 0.0
Val
3.17ValAla: 3.17 ± 1.184
2.264ValCys: 2.264 ± 1.109
3.623ValAsp: 3.623 ± 1.469
4.076ValGlu: 4.076 ± 1.5
3.623ValPhe: 3.623 ± 0.374
2.717ValGly: 2.717 ± 1.572
0.906ValHis: 0.906 ± 0.456
3.17ValIle: 3.17 ± 1.605
4.529ValLys: 4.529 ± 1.015
3.17ValLeu: 3.17 ± 1.819
0.906ValMet: 0.906 ± 0.699
2.264ValAsn: 2.264 ± 0.375
5.888ValPro: 5.888 ± 0.787
3.623ValGln: 3.623 ± 0.881
2.717ValArg: 2.717 ± 1.327
5.888ValSer: 5.888 ± 0.76
3.17ValThr: 3.17 ± 0.991
4.529ValVal: 4.529 ± 1.177
2.264ValTrp: 2.264 ± 0.715
2.264ValTyr: 2.264 ± 1.35
0.0ValXaa: 0.0 ± 0.0
Trp
0.906TrpAla: 0.906 ± 0.745
0.453TrpCys: 0.453 ± 0.395
0.453TrpAsp: 0.453 ± 0.372
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.812TrpGly: 1.812 ± 0.576
0.0TrpHis: 0.0 ± 0.0
1.359TrpIle: 1.359 ± 0.69
0.906TrpLys: 0.906 ± 0.745
1.359TrpLeu: 1.359 ± 0.451
0.0TrpMet: 0.0 ± 0.0
0.906TrpAsn: 0.906 ± 0.931
0.0TrpPro: 0.0 ± 0.0
0.453TrpGln: 0.453 ± 0.372
1.812TrpArg: 1.812 ± 2.002
1.359TrpSer: 1.359 ± 0.92
2.717TrpThr: 2.717 ± 2.37
0.453TrpVal: 0.453 ± 0.372
0.0TrpTrp: 0.0 ± 0.0
0.906TrpTyr: 0.906 ± 0.5
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.359TyrAla: 1.359 ± 0.394
0.906TyrCys: 0.906 ± 0.473
3.17TyrAsp: 3.17 ± 0.691
2.264TyrGlu: 2.264 ± 1.064
1.359TyrPhe: 1.359 ± 0.843
3.17TyrGly: 3.17 ± 1.313
0.453TyrHis: 0.453 ± 0.395
0.0TyrIle: 0.0 ± 0.0
3.17TyrLys: 3.17 ± 0.586
2.717TyrLeu: 2.717 ± 1.368
0.906TyrMet: 0.906 ± 0.535
0.453TyrAsn: 0.453 ± 0.466
3.623TyrPro: 3.623 ± 1.547
1.359TyrGln: 1.359 ± 0.758
1.812TyrArg: 1.812 ± 1.096
0.453TyrSer: 0.453 ± 0.395
1.359TyrThr: 1.359 ± 0.394
3.623TyrVal: 3.623 ± 1.062
1.812TyrTrp: 1.812 ± 0.675
1.812TyrTyr: 1.812 ± 0.777
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2209 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski