Amino acid dipepetide frequency for Xinfangfangia humi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.905AlaAla: 19.905 ± 0.187	1.141AlaCys: 1.141 ± 0.035	6.843AlaAsp: 6.843 ± 0.077	8.87AlaGlu: 8.87 ± 0.106	4.432AlaPhe: 4.432 ± 0.064	12.753AlaGly: 12.753 ± 0.118	2.291AlaHis: 2.291 ± 0.042	5.68AlaIle: 5.68 ± 0.07	3.386AlaLys: 3.386 ± 0.055	15.308AlaLeu: 15.308 ± 0.154	3.804AlaMet: 3.804 ± 0.06	2.402AlaAsn: 2.402 ± 0.044	6.718AlaPro: 6.718 ± 0.08	4.077AlaGln: 4.077 ± 0.065	10.925AlaArg: 10.925 ± 0.109	5.645AlaSer: 5.645 ± 0.065	5.619AlaThr: 5.619 ± 0.073	8.899AlaVal: 8.899 ± 0.09	1.93AlaTrp: 1.93 ± 0.045	2.121AlaTyr: 2.121 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.057CysAla: 1.057 ± 0.03	0.113CysCys: 0.113 ± 0.012	0.58CysAsp: 0.58 ± 0.019	0.468CysGlu: 0.468 ± 0.021	0.316CysPhe: 0.316 ± 0.016	0.991CysGly: 0.991 ± 0.03	0.276CysHis: 0.276 ± 0.016	0.368CysIle: 0.368 ± 0.016	0.178CysLys: 0.178 ± 0.012	0.903CysLeu: 0.903 ± 0.026	0.154CysMet: 0.154 ± 0.01	0.182CysAsn: 0.182 ± 0.012	0.541CysPro: 0.541 ± 0.025	0.259CysGln: 0.259 ± 0.015	0.655CysArg: 0.655 ± 0.026	0.43CysSer: 0.43 ± 0.017	0.43CysThr: 0.43 ± 0.019	0.563CysVal: 0.563 ± 0.022	0.134CysTrp: 0.134 ± 0.01	0.214CysTyr: 0.214 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.273AspAla: 6.273 ± 0.076	0.546AspCys: 0.546 ± 0.019	2.707AspAsp: 2.707 ± 0.055	3.525AspGlu: 3.525 ± 0.058	2.247AspPhe: 2.247 ± 0.04	4.964AspGly: 4.964 ± 0.074	1.316AspHis: 1.316 ± 0.037	2.516AspIle: 2.516 ± 0.048	1.289AspLys: 1.289 ± 0.037	6.721AspLeu: 6.721 ± 0.08	1.417AspMet: 1.417 ± 0.03	1.066AspAsn: 1.066 ± 0.027	4.001AspPro: 4.001 ± 0.05	1.829AspGln: 1.829 ± 0.038	4.341AspArg: 4.341 ± 0.062	2.122AspSer: 2.122 ± 0.043	2.377AspThr: 2.377 ± 0.051	3.346AspVal: 3.346 ± 0.055	1.16AspTrp: 1.16 ± 0.03	1.5AspTyr: 1.5 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	8.913GluAla: 8.913 ± 0.106	0.346GluCys: 0.346 ± 0.018	3.147GluAsp: 3.147 ± 0.052	3.532GluGlu: 3.532 ± 0.067	1.744GluPhe: 1.744 ± 0.038	5.323GluGly: 5.323 ± 0.067	1.069GluHis: 1.069 ± 0.036	3.733GluIle: 3.733 ± 0.05	2.021GluLys: 2.021 ± 0.044	4.976GluLeu: 4.976 ± 0.064	1.673GluMet: 1.673 ± 0.041	1.539GluAsn: 1.539 ± 0.031	2.711GluPro: 2.711 ± 0.049	1.745GluGln: 1.745 ± 0.038	4.608GluArg: 4.608 ± 0.072	2.307GluSer: 2.307 ± 0.044	3.686GluThr: 3.686 ± 0.057	4.323GluVal: 4.323 ± 0.068	0.708GluTrp: 0.708 ± 0.023	1.074GluTyr: 1.074 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.606PheAla: 4.606 ± 0.063	0.428PheCys: 0.428 ± 0.019	2.539PheAsp: 2.539 ± 0.05	1.875PheGlu: 1.875 ± 0.039	1.29PhePhe: 1.29 ± 0.035	3.657PheGly: 3.657 ± 0.056	0.75PheHis: 0.75 ± 0.024	1.51PheIle: 1.51 ± 0.035	0.563PheLys: 0.563 ± 0.022	3.597PheLeu: 3.597 ± 0.061	0.75PheMet: 0.75 ± 0.026	0.873PheAsn: 0.873 ± 0.028	1.666PhePro: 1.666 ± 0.034	0.941PheGln: 0.941 ± 0.025	2.678PheArg: 2.678 ± 0.044	2.138PheSer: 2.138 ± 0.043	2.09PheThr: 2.09 ± 0.041	2.305PheVal: 2.305 ± 0.049	0.587PheTrp: 0.587 ± 0.025	0.823PheTyr: 0.823 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	11.123GlyAla: 11.123 ± 0.111	0.867GlyCys: 0.867 ± 0.029	4.564GlyAsp: 4.564 ± 0.08	5.418GlyGlu: 5.418 ± 0.072	3.765GlyPhe: 3.765 ± 0.057	8.339GlyGly: 8.339 ± 0.119	2.034GlyHis: 2.034 ± 0.047	4.66GlyIle: 4.66 ± 0.068	2.96GlyLys: 2.96 ± 0.055	10.249GlyLeu: 10.249 ± 0.113	2.719GlyMet: 2.719 ± 0.048	2.055GlyAsn: 2.055 ± 0.05	4.302GlyPro: 4.302 ± 0.051	3.18GlyGln: 3.18 ± 0.055	7.147GlyArg: 7.147 ± 0.079	4.343GlySer: 4.343 ± 0.052	4.352GlyThr: 4.352 ± 0.072	6.26GlyVal: 6.26 ± 0.07	1.647GlyTrp: 1.647 ± 0.041	2.19GlyTyr: 2.19 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.272HisAla: 2.272 ± 0.048	0.233HisCys: 0.233 ± 0.014	1.247HisAsp: 1.247 ± 0.034	1.128HisGlu: 1.128 ± 0.034	0.778HisPhe: 0.778 ± 0.029	1.945HisGly: 1.945 ± 0.044	0.511HisHis: 0.511 ± 0.023	0.96HisIle: 0.96 ± 0.023	0.426HisLys: 0.426 ± 0.018	2.166HisLeu: 2.166 ± 0.045	0.501HisMet: 0.501 ± 0.021	0.404HisAsn: 0.404 ± 0.017	1.463HisPro: 1.463 ± 0.034	0.556HisGln: 0.556 ± 0.019	1.466HisArg: 1.466 ± 0.036	0.932HisSer: 0.932 ± 0.027	0.708HisThr: 0.708 ± 0.025	1.354HisVal: 1.354 ± 0.038	0.359HisTrp: 0.359 ± 0.017	0.556HisTyr: 0.556 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.087IleAla: 7.087 ± 0.085	0.632IleCys: 0.632 ± 0.025	3.152IleAsp: 3.152 ± 0.051	3.193IleGlu: 3.193 ± 0.047	1.702IlePhe: 1.702 ± 0.036	5.04IleGly: 5.04 ± 0.073	0.923IleHis: 0.923 ± 0.029	1.783IleIle: 1.783 ± 0.047	0.857IleLys: 0.857 ± 0.028	4.904IleLeu: 4.904 ± 0.065	0.981IleMet: 0.981 ± 0.033	1.155IleAsn: 1.155 ± 0.031	2.408IlePro: 2.408 ± 0.049	1.073IleGln: 1.073 ± 0.027	4.04IleArg: 4.04 ± 0.055	2.754IleSer: 2.754 ± 0.048	2.816IleThr: 2.816 ± 0.048	3.33IleVal: 3.33 ± 0.062	0.76IleTrp: 0.76 ± 0.024	0.986IleTyr: 0.986 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.519LysAla: 3.519 ± 0.062	0.163LysCys: 0.163 ± 0.012	1.394LysAsp: 1.394 ± 0.036	1.283LysGlu: 1.283 ± 0.042	0.757LysPhe: 0.757 ± 0.023	2.524LysGly: 2.524 ± 0.053	0.509LysHis: 0.509 ± 0.018	1.493LysIle: 1.493 ± 0.036	0.993LysLys: 0.993 ± 0.034	2.588LysLeu: 2.588 ± 0.046	0.688LysMet: 0.688 ± 0.024	0.653LysAsn: 0.653 ± 0.024	1.663LysPro: 1.663 ± 0.037	0.751LysGln: 0.751 ± 0.024	1.897LysArg: 1.897 ± 0.048	1.466LysSer: 1.466 ± 0.04	1.587LysThr: 1.587 ± 0.033	1.99LysVal: 1.99 ± 0.043	0.35LysTrp: 0.35 ± 0.016	0.563LysTyr: 0.563 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	15.529LeuAla: 15.529 ± 0.155	0.998LeuCys: 0.998 ± 0.026	5.758LeuAsp: 5.758 ± 0.086	5.205LeuGlu: 5.205 ± 0.061	3.438LeuPhe: 3.438 ± 0.059	8.521LeuGly: 8.521 ± 0.092	1.973LeuHis: 1.973 ± 0.045	5.542LeuIle: 5.542 ± 0.072	3.07LeuLys: 3.07 ± 0.051	9.248LeuLeu: 9.248 ± 0.112	2.742LeuMet: 2.742 ± 0.049	2.568LeuAsn: 2.568 ± 0.046	6.389LeuPro: 6.389 ± 0.096	2.401LeuGln: 2.401 ± 0.044	8.261LeuArg: 8.261 ± 0.083	6.826LeuSer: 6.826 ± 0.079	6.163LeuThr: 6.163 ± 0.07	6.923LeuVal: 6.923 ± 0.086	1.465LeuTrp: 1.465 ± 0.042	1.998LeuTyr: 1.998 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	3.514MetAla: 3.514 ± 0.056	0.153MetCys: 0.153 ± 0.011	1.238MetAsp: 1.238 ± 0.034	1.32MetGlu: 1.32 ± 0.034	0.736MetPhe: 0.736 ± 0.027	2.122MetGly: 2.122 ± 0.043	0.37MetHis: 0.37 ± 0.016	1.51MetIle: 1.51 ± 0.032	0.925MetLys: 0.925 ± 0.027	2.569MetLeu: 2.569 ± 0.049	0.675MetMet: 0.675 ± 0.023	0.763MetAsn: 0.763 ± 0.026	1.496MetPro: 1.496 ± 0.033	0.871MetGln: 0.871 ± 0.024	1.975MetArg: 1.975 ± 0.04	1.56MetSer: 1.56 ± 0.035	1.928MetThr: 1.928 ± 0.034	1.799MetVal: 1.799 ± 0.043	0.201MetTrp: 0.201 ± 0.012	0.271MetTyr: 0.271 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.691AsnAla: 2.691 ± 0.044	0.221AsnCys: 0.221 ± 0.013	1.229AsnAsp: 1.229 ± 0.047	1.086AsnGlu: 1.086 ± 0.029	0.828AsnPhe: 0.828 ± 0.025	2.081AsnGly: 2.081 ± 0.046	0.46AsnHis: 0.46 ± 0.018	1.198AsnIle: 1.198 ± 0.035	0.492AsnLys: 0.492 ± 0.021	2.339AsnLeu: 2.339 ± 0.043	0.592AsnMet: 0.592 ± 0.019	0.5AsnAsn: 0.5 ± 0.02	1.799AsnPro: 1.799 ± 0.035	0.599AsnGln: 0.599 ± 0.025	1.795AsnArg: 1.795 ± 0.038	1.01AsnSer: 1.01 ± 0.031	1.139AsnThr: 1.139 ± 0.035	1.537AsnVal: 1.537 ± 0.038	0.415AsnTrp: 0.415 ± 0.019	0.595AsnTyr: 0.595 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.664ProAla: 7.664 ± 0.085	0.402ProCys: 0.402 ± 0.02	3.847ProAsp: 3.847 ± 0.056	4.503ProGlu: 4.503 ± 0.057	1.964ProPhe: 1.964 ± 0.041	6.228ProGly: 6.228 ± 0.076	1.094ProHis: 1.094 ± 0.03	1.763ProIle: 1.763 ± 0.036	1.467ProLys: 1.467 ± 0.036	5.143ProLeu: 5.143 ± 0.067	1.297ProMet: 1.297 ± 0.03	1.054ProAsn: 1.054 ± 0.027	2.883ProPro: 2.883 ± 0.06	1.695ProGln: 1.695 ± 0.037	3.318ProArg: 3.318 ± 0.061	2.391ProSer: 2.391 ± 0.048	1.972ProThr: 1.972 ± 0.041	4.923ProVal: 4.923 ± 0.062	0.838ProTrp: 0.838 ± 0.028	1.036ProTyr: 1.036 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.769GlnAla: 3.769 ± 0.064	0.182GlnCys: 0.182 ± 0.013	1.56GlnAsp: 1.56 ± 0.037	1.523GlnGlu: 1.523 ± 0.035	0.934GlnPhe: 0.934 ± 0.027	2.738GlnGly: 2.738 ± 0.038	0.556GlnHis: 0.556 ± 0.024	1.945GlnIle: 1.945 ± 0.042	0.989GlnLys: 0.989 ± 0.028	2.613GlnLeu: 2.613 ± 0.047	0.902GlnMet: 0.902 ± 0.03	0.786GlnAsn: 0.786 ± 0.026	1.67GlnPro: 1.67 ± 0.038	0.961GlnGln: 0.961 ± 0.032	2.113GlnArg: 2.113 ± 0.039	1.645GlnSer: 1.645 ± 0.039	1.57GlnThr: 1.57 ± 0.036	2.197GlnVal: 2.197 ± 0.044	0.329GlnTrp: 0.329 ± 0.016	0.506GlnTyr: 0.506 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	9.917ArgAla: 9.917 ± 0.093	0.493ArgCys: 0.493 ± 0.019	4.348ArgAsp: 4.348 ± 0.066	4.661ArgGlu: 4.661 ± 0.073	2.849ArgPhe: 2.849 ± 0.048	5.543ArgGly: 5.543 ± 0.065	1.799ArgHis: 1.799 ± 0.037	4.638ArgIle: 4.638 ± 0.06	2.071ArgLys: 2.071 ± 0.043	9.041ArgLeu: 9.041 ± 0.11	2.048ArgMet: 2.048 ± 0.038	1.775ArgAsn: 1.775 ± 0.036	4.13ArgPro: 4.13 ± 0.064	2.606ArgGln: 2.606 ± 0.047	6.326ArgArg: 6.326 ± 0.095	3.398ArgSer: 3.398 ± 0.056	2.842ArgThr: 2.842 ± 0.048	4.951ArgVal: 4.951 ± 0.064	1.032ArgTrp: 1.032 ± 0.032	1.581ArgTyr: 1.581 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.04SerAla: 6.04 ± 0.085	0.483SerCys: 0.483 ± 0.022	2.866SerAsp: 2.866 ± 0.046	2.65SerGlu: 2.65 ± 0.044	2.107SerPhe: 2.107 ± 0.042	5.768SerGly: 5.768 ± 0.074	1.037SerHis: 1.037 ± 0.027	2.004SerIle: 2.004 ± 0.04	1.18SerLys: 1.18 ± 0.033	5.209SerLeu: 5.209 ± 0.08	1.105SerMet: 1.105 ± 0.028	1.053SerAsn: 1.053 ± 0.034	2.827SerPro: 2.827 ± 0.048	1.46SerGln: 1.46 ± 0.037	3.689SerArg: 3.689 ± 0.061	2.318SerSer: 2.318 ± 0.053	2.18SerThr: 2.18 ± 0.045	3.74SerVal: 3.74 ± 0.056	0.758SerTrp: 0.758 ± 0.026	1.229SerTyr: 1.229 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	6.137ThrAla: 6.137 ± 0.077	0.474ThrCys: 0.474 ± 0.021	2.714ThrAsp: 2.714 ± 0.047	2.809ThrGlu: 2.809 ± 0.047	1.713ThrPhe: 1.713 ± 0.034	5.717ThrGly: 5.717 ± 0.073	0.984ThrHis: 0.984 ± 0.029	2.471ThrIle: 2.471 ± 0.051	1.085ThrLys: 1.085 ± 0.032	5.541ThrLeu: 5.541 ± 0.073	1.103ThrMet: 1.103 ± 0.031	1.07ThrAsn: 1.07 ± 0.026	3.382ThrPro: 3.382 ± 0.057	1.179ThrGln: 1.179 ± 0.031	3.539ThrArg: 3.539 ± 0.055	2.418ThrSer: 2.418 ± 0.043	2.463ThrThr: 2.463 ± 0.045	3.816ThrVal: 3.816 ± 0.066	0.73ThrTrp: 0.73 ± 0.021	0.954ThrTyr: 0.954 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	8.928ValAla: 8.928 ± 0.09	0.581ValCys: 0.581 ± 0.024	3.381ValAsp: 3.381 ± 0.055	4.11ValGlu: 4.11 ± 0.058	2.706ValPhe: 2.706 ± 0.05	4.807ValGly: 4.807 ± 0.058	1.182ValHis: 1.182 ± 0.031	4.166ValIle: 4.166 ± 0.058	1.948ValLys: 1.948 ± 0.046	7.805ValLeu: 7.805 ± 0.085	2.039ValMet: 2.039 ± 0.042	1.74ValAsn: 1.74 ± 0.039	3.6ValPro: 3.6 ± 0.052	2.0ValGln: 2.0 ± 0.044	4.395ValArg: 4.395 ± 0.062	4.093ValSer: 4.093 ± 0.059	4.585ValThr: 4.585 ± 0.067	5.331ValVal: 5.331 ± 0.07	1.049ValTrp: 1.049 ± 0.032	1.311ValTyr: 1.311 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.449TrpAla: 1.449 ± 0.036	0.148TrpCys: 0.148 ± 0.009	0.732TrpAsp: 0.732 ± 0.024	0.754TrpGlu: 0.754 ± 0.022	0.617TrpPhe: 0.617 ± 0.022	1.061TrpGly: 1.061 ± 0.032	0.364TrpHis: 0.364 ± 0.019	0.772TrpIle: 0.772 ± 0.024	0.481TrpLys: 0.481 ± 0.02	2.007TrpLeu: 2.007 ± 0.049	0.373TrpMet: 0.373 ± 0.018	0.437TrpAsn: 0.437 ± 0.021	0.854TrpPro: 0.854 ± 0.029	0.709TrpGln: 0.709 ± 0.024	1.265TrpArg: 1.265 ± 0.034	0.867TrpSer: 0.867 ± 0.023	0.791TrpThr: 0.791 ± 0.027	0.801TrpVal: 0.801 ± 0.026	0.248TrpTrp: 0.248 ± 0.014	0.307TrpTyr: 0.307 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.352TyrAla: 2.352 ± 0.042	0.208TyrCys: 0.208 ± 0.013	1.417TyrAsp: 1.417 ± 0.034	1.266TyrGlu: 1.266 ± 0.038	0.742TyrPhe: 0.742 ± 0.023	2.052TyrGly: 2.052 ± 0.042	0.466TyrHis: 0.466 ± 0.02	0.861TyrIle: 0.861 ± 0.025	0.452TyrLys: 0.452 ± 0.022	2.09TyrLeu: 2.09 ± 0.044	0.43TyrMet: 0.43 ± 0.019	0.532TyrAsn: 0.532 ± 0.02	0.979TyrPro: 0.979 ± 0.03	0.599TyrGln: 0.599 ± 0.023	1.618TyrArg: 1.618 ± 0.036	1.041TyrSer: 1.041 ± 0.028	1.003TyrThr: 1.003 ± 0.03	1.37TyrVal: 1.37 ± 0.034	0.338TyrTrp: 0.338 ± 0.017	0.535TyrTyr: 0.535 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4199 proteins (1295700 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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