Amino acid dipepetide frequency for Aidingimonas halophila

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.332AlaAla: 10.332 ± 0.129	1.212AlaCys: 1.212 ± 0.034	6.166AlaAsp: 6.166 ± 0.081	6.655AlaGlu: 6.655 ± 0.089	3.759AlaPhe: 3.759 ± 0.062	8.365AlaGly: 8.365 ± 0.112	2.248AlaHis: 2.248 ± 0.053	5.702AlaIle: 5.702 ± 0.08	2.542AlaLys: 2.542 ± 0.049	12.497AlaLeu: 12.497 ± 0.123	3.376AlaMet: 3.376 ± 0.06	2.654AlaAsn: 2.654 ± 0.046	4.054AlaPro: 4.054 ± 0.067	3.538AlaGln: 3.538 ± 0.056	7.062AlaArg: 7.062 ± 0.08	6.279AlaSer: 6.279 ± 0.085	5.133AlaThr: 5.133 ± 0.065	7.137AlaVal: 7.137 ± 0.087	1.728AlaTrp: 1.728 ± 0.044	2.45AlaTyr: 2.45 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	0.849CysAla: 0.849 ± 0.028	0.142CysCys: 0.142 ± 0.012	0.617CysAsp: 0.617 ± 0.025	0.538CysGlu: 0.538 ± 0.019	0.362CysPhe: 0.362 ± 0.018	0.957CysGly: 0.957 ± 0.031	0.39CysHis: 0.39 ± 0.018	0.458CysIle: 0.458 ± 0.022	0.201CysLys: 0.201 ± 0.014	1.131CysLeu: 1.131 ± 0.03	0.213CysMet: 0.213 ± 0.014	0.24CysAsn: 0.24 ± 0.015	0.509CysPro: 0.509 ± 0.022	0.405CysGln: 0.405 ± 0.02	0.826CysArg: 0.826 ± 0.029	0.495CysSer: 0.495 ± 0.023	0.423CysThr: 0.423 ± 0.02	0.675CysVal: 0.675 ± 0.024	0.146CysTrp: 0.146 ± 0.01	0.249CysTyr: 0.249 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.715AspAla: 6.715 ± 0.089	0.528AspCys: 0.528 ± 0.025	5.059AspAsp: 5.059 ± 0.114	4.679AspGlu: 4.679 ± 0.084	2.129AspPhe: 2.129 ± 0.047	4.908AspGly: 4.908 ± 0.101	1.621AspHis: 1.621 ± 0.039	3.723AspIle: 3.723 ± 0.078	1.684AspLys: 1.684 ± 0.041	5.673AspLeu: 5.673 ± 0.081	1.592AspMet: 1.592 ± 0.041	1.944AspAsn: 1.944 ± 0.047	3.139AspPro: 3.139 ± 0.052	2.13AspGln: 2.13 ± 0.045	4.029AspArg: 4.029 ± 0.062	3.282AspSer: 3.282 ± 0.068	3.581AspThr: 3.581 ± 0.064	4.551AspVal: 4.551 ± 0.073	1.064AspTrp: 1.064 ± 0.033	1.853AspTyr: 1.853 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	7.439GluAla: 7.439 ± 0.101	0.539GluCys: 0.539 ± 0.021	3.369GluAsp: 3.369 ± 0.072	4.246GluGlu: 4.246 ± 0.079	1.757GluPhe: 1.757 ± 0.037	4.8GluGly: 4.8 ± 0.071	1.776GluHis: 1.776 ± 0.041	3.067GluIle: 3.067 ± 0.049	1.718GluLys: 1.718 ± 0.048	6.83GluLeu: 6.83 ± 0.089	1.586GluMet: 1.586 ± 0.041	1.66GluAsn: 1.66 ± 0.034	2.832GluPro: 2.832 ± 0.071	3.104GluGln: 3.104 ± 0.049	6.017GluArg: 6.017 ± 0.082	3.756GluSer: 3.756 ± 0.061	3.705GluThr: 3.705 ± 0.058	4.283GluVal: 4.283 ± 0.058	0.955GluTrp: 0.955 ± 0.036	1.36GluTyr: 1.36 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.357PheAla: 3.357 ± 0.062	0.369PheCys: 0.369 ± 0.017	2.594PheAsp: 2.594 ± 0.051	2.064PheGlu: 2.064 ± 0.047	1.354PhePhe: 1.354 ± 0.04	3.083PheGly: 3.083 ± 0.057	0.894PheHis: 0.894 ± 0.028	1.803PheIle: 1.803 ± 0.05	0.9PheLys: 0.9 ± 0.031	3.37PheLeu: 3.37 ± 0.064	0.895PheMet: 0.895 ± 0.03	1.038PheAsn: 1.038 ± 0.028	1.439PhePro: 1.439 ± 0.04	1.198PheGln: 1.198 ± 0.029	2.038PheArg: 2.038 ± 0.048	2.332PheSer: 2.332 ± 0.044	1.89PheThr: 1.89 ± 0.043	2.392PheVal: 2.392 ± 0.051	0.503PheTrp: 0.503 ± 0.023	0.96PheTyr: 0.96 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	6.972GlyAla: 6.972 ± 0.092	0.943GlyCys: 0.943 ± 0.03	4.97GlyAsp: 4.97 ± 0.146	5.473GlyGlu: 5.473 ± 0.09	3.14GlyPhe: 3.14 ± 0.055	6.583GlyGly: 6.583 ± 0.14	2.13GlyHis: 2.13 ± 0.043	4.791GlyIle: 4.791 ± 0.072	2.561GlyLys: 2.561 ± 0.05	8.704GlyLeu: 8.704 ± 0.102	2.558GlyMet: 2.558 ± 0.049	2.345GlyAsn: 2.345 ± 0.058	2.675GlyPro: 2.675 ± 0.043	3.062GlyGln: 3.062 ± 0.049	5.304GlyArg: 5.304 ± 0.084	4.384GlySer: 4.384 ± 0.089	3.93GlyThr: 3.93 ± 0.065	6.078GlyVal: 6.078 ± 0.077	1.336GlyTrp: 1.336 ± 0.032	2.465GlyTyr: 2.465 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.493HisAla: 2.493 ± 0.047	0.343HisCys: 0.343 ± 0.019	1.882HisAsp: 1.882 ± 0.046	1.526HisGlu: 1.526 ± 0.04	1.041HisPhe: 1.041 ± 0.036	2.259HisGly: 2.259 ± 0.045	0.932HisHis: 0.932 ± 0.031	1.143HisIle: 1.143 ± 0.028	0.502HisLys: 0.502 ± 0.021	2.73HisLeu: 2.73 ± 0.054	0.557HisMet: 0.557 ± 0.022	0.549HisAsn: 0.549 ± 0.02	1.594HisPro: 1.594 ± 0.043	1.052HisGln: 1.052 ± 0.031	1.937HisArg: 1.937 ± 0.042	1.244HisSer: 1.244 ± 0.031	1.101HisThr: 1.101 ± 0.028	1.714HisVal: 1.714 ± 0.042	0.468HisTrp: 0.468 ± 0.022	0.853HisTyr: 0.853 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.085IleAla: 6.085 ± 0.08	0.45IleCys: 0.45 ± 0.021	4.175IleAsp: 4.175 ± 0.067	3.707IleGlu: 3.707 ± 0.054	1.509IlePhe: 1.509 ± 0.043	4.678IleGly: 4.678 ± 0.073	1.183IleHis: 1.183 ± 0.032	2.347IleIle: 2.347 ± 0.053	1.356IleLys: 1.356 ± 0.034	4.504IleLeu: 4.504 ± 0.062	1.088IleMet: 1.088 ± 0.031	1.661IleAsn: 1.661 ± 0.038	2.531IlePro: 2.531 ± 0.047	1.583IleGln: 1.583 ± 0.04	3.115IleArg: 3.115 ± 0.058	2.844IleSer: 2.844 ± 0.052	2.692IleThr: 2.692 ± 0.049	3.665IleVal: 3.665 ± 0.065	0.561IleTrp: 0.561 ± 0.022	1.09IleTyr: 1.09 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	2.884LysAla: 2.884 ± 0.062	0.189LysCys: 0.189 ± 0.013	1.284LysAsp: 1.284 ± 0.039	1.544LysGlu: 1.544 ± 0.039	0.561LysPhe: 0.561 ± 0.022	2.078LysGly: 2.078 ± 0.045	0.678LysHis: 0.678 ± 0.025	1.091LysIle: 1.091 ± 0.035	0.889LysLys: 0.889 ± 0.034	2.568LysLeu: 2.568 ± 0.059	0.577LysMet: 0.577 ± 0.027	0.626LysAsn: 0.626 ± 0.028	1.414LysPro: 1.414 ± 0.038	1.125LysGln: 1.125 ± 0.033	2.348LysArg: 2.348 ± 0.052	1.478LysSer: 1.478 ± 0.038	1.397LysThr: 1.397 ± 0.038	1.912LysVal: 1.912 ± 0.047	0.279LysTrp: 0.279 ± 0.013	0.531LysTyr: 0.531 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.147LeuAla: 13.147 ± 0.125	1.139LeuCys: 1.139 ± 0.032	7.548LeuAsp: 7.548 ± 0.09	7.226LeuGlu: 7.226 ± 0.094	3.816LeuPhe: 3.816 ± 0.076	8.949LeuGly: 8.949 ± 0.094	2.412LeuHis: 2.412 ± 0.051	5.652LeuIle: 5.652 ± 0.091	3.138LeuLys: 3.138 ± 0.057	11.52LeuLeu: 11.52 ± 0.142	2.962LeuMet: 2.962 ± 0.055	2.937LeuAsn: 2.937 ± 0.054	5.895LeuPro: 5.895 ± 0.085	3.372LeuGln: 3.372 ± 0.058	6.579LeuArg: 6.579 ± 0.089	7.148LeuSer: 7.148 ± 0.085	6.006LeuThr: 6.006 ± 0.074	7.703LeuVal: 7.703 ± 0.085	1.453LeuTrp: 1.453 ± 0.042	2.411LeuTyr: 2.411 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	3.199MetAla: 3.199 ± 0.056	0.183MetCys: 0.183 ± 0.012	1.243MetAsp: 1.243 ± 0.034	1.38MetGlu: 1.38 ± 0.037	0.692MetPhe: 0.692 ± 0.03	1.939MetGly: 1.939 ± 0.042	0.595MetHis: 0.595 ± 0.02	1.402MetIle: 1.402 ± 0.037	0.83MetLys: 0.83 ± 0.026	2.824MetLeu: 2.824 ± 0.05	0.703MetMet: 0.703 ± 0.025	0.855MetAsn: 0.855 ± 0.028	1.513MetPro: 1.513 ± 0.039	1.041MetGln: 1.041 ± 0.03	1.694MetArg: 1.694 ± 0.035	1.865MetSer: 1.865 ± 0.039	1.986MetThr: 1.986 ± 0.039	1.854MetVal: 1.854 ± 0.043	0.234MetTrp: 0.234 ± 0.012	0.375MetTyr: 0.375 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.882AsnAla: 2.882 ± 0.054	0.24AsnCys: 0.24 ± 0.013	1.88AsnAsp: 1.88 ± 0.042	1.637AsnGlu: 1.637 ± 0.032	0.84AsnPhe: 0.84 ± 0.027	2.215AsnGly: 2.215 ± 0.049	0.652AsnHis: 0.652 ± 0.023	1.346AsnIle: 1.346 ± 0.035	0.631AsnLys: 0.631 ± 0.027	2.744AsnLeu: 2.744 ± 0.051	0.621AsnMet: 0.621 ± 0.024	0.743AsnAsn: 0.743 ± 0.03	1.582AsnPro: 1.582 ± 0.037	1.007AsnGln: 1.007 ± 0.034	1.976AsnArg: 1.976 ± 0.046	1.294AsnSer: 1.294 ± 0.034	1.418AsnThr: 1.418 ± 0.036	1.989AsnVal: 1.989 ± 0.046	0.383AsnTrp: 0.383 ± 0.017	0.68AsnTyr: 0.68 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	4.478ProAla: 4.478 ± 0.07	0.366ProCys: 0.366 ± 0.016	3.679ProAsp: 3.679 ± 0.051	3.812ProGlu: 3.812 ± 0.068	1.78ProPhe: 1.78 ± 0.039	4.082ProGly: 4.082 ± 0.061	1.158ProHis: 1.158 ± 0.036	2.163ProIle: 2.163 ± 0.052	1.098ProLys: 1.098 ± 0.029	5.314ProLeu: 5.314 ± 0.083	1.275ProMet: 1.275 ± 0.03	1.211ProAsn: 1.211 ± 0.034	2.118ProPro: 2.118 ± 0.042	1.646ProGln: 1.646 ± 0.04	2.844ProArg: 2.844 ± 0.052	2.807ProSer: 2.807 ± 0.05	2.35ProThr: 2.35 ± 0.047	3.642ProVal: 3.642 ± 0.068	0.857ProTrp: 0.857 ± 0.024	1.195ProTyr: 1.195 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.833GlnAla: 4.833 ± 0.082	0.33GlnCys: 0.33 ± 0.018	1.831GlnAsp: 1.831 ± 0.043	2.236GlnGlu: 2.236 ± 0.046	1.057GlnPhe: 1.057 ± 0.027	3.153GlnGly: 3.153 ± 0.053	1.041GlnHis: 1.041 ± 0.032	1.455GlnIle: 1.455 ± 0.039	0.816GlnLys: 0.816 ± 0.027	4.179GlnLeu: 4.179 ± 0.07	0.824GlnMet: 0.824 ± 0.025	0.804GlnAsn: 0.804 ± 0.029	1.877GlnPro: 1.877 ± 0.043	2.063GlnGln: 2.063 ± 0.054	3.6GlnArg: 3.6 ± 0.062	2.12GlnSer: 2.12 ± 0.044	1.648GlnThr: 1.648 ± 0.038	2.804GlnVal: 2.804 ± 0.049	0.669GlnTrp: 0.669 ± 0.021	0.85GlnTyr: 0.85 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	5.799ArgAla: 5.799 ± 0.078	0.646ArgCys: 0.646 ± 0.023	4.461ArgAsp: 4.461 ± 0.075	5.097ArgGlu: 5.097 ± 0.072	2.882ArgPhe: 2.882 ± 0.046	4.312ArgGly: 4.312 ± 0.058	2.478ArgHis: 2.478 ± 0.053	3.685ArgIle: 3.685 ± 0.051	1.703ArgLys: 1.703 ± 0.04	9.364ArgLeu: 9.364 ± 0.125	1.749ArgMet: 1.749 ± 0.037	1.763ArgAsn: 1.763 ± 0.038	2.944ArgPro: 2.944 ± 0.053	3.568ArgGln: 3.568 ± 0.063	5.681ArgArg: 5.681 ± 0.089	3.491ArgSer: 3.491 ± 0.053	2.886ArgThr: 2.886 ± 0.047	4.805ArgVal: 4.805 ± 0.062	1.126ArgTrp: 1.126 ± 0.039	2.304ArgTyr: 2.304 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.398SerAla: 5.398 ± 0.068	0.499SerCys: 0.499 ± 0.024	3.554SerAsp: 3.554 ± 0.06	3.447SerGlu: 3.447 ± 0.064	1.984SerPhe: 1.984 ± 0.053	5.226SerGly: 5.226 ± 0.071	1.612SerHis: 1.612 ± 0.039	2.673SerIle: 2.673 ± 0.048	1.203SerLys: 1.203 ± 0.035	7.098SerLeu: 7.098 ± 0.09	1.634SerMet: 1.634 ± 0.036	1.439SerAsn: 1.439 ± 0.032	2.957SerPro: 2.957 ± 0.053	2.315SerGln: 2.315 ± 0.049	4.447SerArg: 4.447 ± 0.059	3.58SerSer: 3.58 ± 0.057	2.824SerThr: 2.824 ± 0.046	3.983SerVal: 3.983 ± 0.071	0.808SerTrp: 0.808 ± 0.026	1.363SerTyr: 1.363 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	5.138ThrAla: 5.138 ± 0.066	0.469ThrCys: 0.469 ± 0.022	2.797ThrAsp: 2.797 ± 0.052	2.745ThrGlu: 2.745 ± 0.044	1.826ThrPhe: 1.826 ± 0.039	4.394ThrGly: 4.394 ± 0.074	1.338ThrHis: 1.338 ± 0.041	2.397ThrIle: 2.397 ± 0.048	0.953ThrLys: 0.953 ± 0.031	7.24ThrLeu: 7.24 ± 0.091	1.177ThrMet: 1.177 ± 0.038	1.206ThrAsn: 1.206 ± 0.03	3.373ThrPro: 3.373 ± 0.057	1.827ThrGln: 1.827 ± 0.041	3.543ThrArg: 3.543 ± 0.057	2.953ThrSer: 2.953 ± 0.051	2.887ThrThr: 2.887 ± 0.063	3.681ThrVal: 3.681 ± 0.064	0.709ThrTrp: 0.709 ± 0.027	1.2ThrTyr: 1.2 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	7.523ValAla: 7.523 ± 0.086	0.739ValCys: 0.739 ± 0.025	4.609ValAsp: 4.609 ± 0.094	4.718ValGlu: 4.718 ± 0.066	2.496ValPhe: 2.496 ± 0.047	5.361ValGly: 5.361 ± 0.076	1.523ValHis: 1.523 ± 0.04	4.219ValIle: 4.219 ± 0.061	1.848ValLys: 1.848 ± 0.042	7.364ValLeu: 7.364 ± 0.088	2.124ValMet: 2.124 ± 0.042	2.099ValAsn: 2.099 ± 0.043	3.376ValPro: 3.376 ± 0.051	2.063ValGln: 2.063 ± 0.046	4.2ValArg: 4.2 ± 0.07	4.512ValSer: 4.512 ± 0.067	4.228ValThr: 4.228 ± 0.065	5.556ValVal: 5.556 ± 0.079	0.859ValTrp: 0.859 ± 0.028	1.548ValTyr: 1.548 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.035TrpAla: 1.035 ± 0.034	0.189TrpCys: 0.189 ± 0.014	0.601TrpAsp: 0.601 ± 0.028	0.742TrpGlu: 0.742 ± 0.027	0.567TrpPhe: 0.567 ± 0.021	0.914TrpGly: 0.914 ± 0.032	0.515TrpHis: 0.515 ± 0.023	0.702TrpIle: 0.702 ± 0.024	0.351TrpLys: 0.351 ± 0.02	2.427TrpLeu: 2.427 ± 0.054	0.398TrpMet: 0.398 ± 0.02	0.394TrpAsn: 0.394 ± 0.016	0.756TrpPro: 0.756 ± 0.026	0.931TrpGln: 0.931 ± 0.03	1.235TrpArg: 1.235 ± 0.035	0.853TrpSer: 0.853 ± 0.031	0.631TrpThr: 0.631 ± 0.025	0.954TrpVal: 0.954 ± 0.03	0.306TrpTrp: 0.306 ± 0.017	0.349TrpTyr: 0.349 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.331TyrAla: 2.331 ± 0.047	0.311TyrCys: 0.311 ± 0.017	1.565TyrAsp: 1.565 ± 0.046	1.328TyrGlu: 1.328 ± 0.033	0.922TyrPhe: 0.922 ± 0.029	2.147TyrGly: 2.147 ± 0.043	0.743TyrHis: 0.743 ± 0.025	1.004TyrIle: 1.004 ± 0.031	0.527TyrLys: 0.527 ± 0.023	2.935TyrLeu: 2.935 ± 0.047	0.5TyrMet: 0.5 ± 0.022	0.595TyrAsn: 0.595 ± 0.023	1.3TyrPro: 1.3 ± 0.035	1.159TyrGln: 1.159 ± 0.032	2.271TyrArg: 2.271 ± 0.047	1.325TyrSer: 1.325 ± 0.035	1.137TyrThr: 1.137 ± 0.033	1.584TyrVal: 1.584 ± 0.043	0.403TyrTrp: 0.403 ± 0.019	0.737TyrTyr: 0.737 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3626 proteins (1177209 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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