Amino acid dipepetide frequency for Cauliflower mosaic virus (strain Strasbourg) (CaMV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.91AlaAla: 3.91 ± 1.211
0.0AlaCys: 0.0 ± 0.0
2.606AlaAsp: 2.606 ± 0.662
3.041AlaGlu: 3.041 ± 1.497
1.738AlaPhe: 1.738 ± 0.94
1.738AlaGly: 1.738 ± 0.774
1.303AlaHis: 1.303 ± 0.784
4.778AlaIle: 4.778 ± 0.966
4.778AlaLys: 4.778 ± 0.699
3.475AlaLeu: 3.475 ± 1.501
1.738AlaMet: 1.738 ± 0.534
2.606AlaAsn: 2.606 ± 1.202
3.041AlaPro: 3.041 ± 1.425
2.606AlaGln: 2.606 ± 0.883
1.303AlaArg: 1.303 ± 0.8
3.91AlaSer: 3.91 ± 1.598
2.606AlaThr: 2.606 ± 1.076
2.606AlaVal: 2.606 ± 0.947
0.434AlaTrp: 0.434 ± 0.331
2.172AlaTyr: 2.172 ± 0.509
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.869CysCys: 0.869 ± 0.417
1.738CysAsp: 1.738 ± 0.994
0.0CysGlu: 0.0 ± 0.0
0.434CysPhe: 0.434 ± 0.331
0.434CysGly: 0.434 ± 0.416
0.869CysHis: 0.869 ± 0.815
0.869CysIle: 0.869 ± 0.392
1.303CysLys: 1.303 ± 0.669
0.869CysLeu: 0.869 ± 0.492
0.0CysMet: 0.0 ± 0.0
1.738CysAsn: 1.738 ± 0.621
2.172CysPro: 2.172 ± 0.633
0.869CysGln: 0.869 ± 0.417
0.869CysArg: 0.869 ± 0.417
0.869CysSer: 0.869 ± 0.417
0.869CysThr: 0.869 ± 0.491
0.869CysVal: 0.869 ± 0.437
0.434CysTrp: 0.434 ± 0.346
0.434CysTyr: 0.434 ± 0.346
0.0CysXaa: 0.0 ± 0.0
Asp
3.041AspAla: 3.041 ± 0.775
2.606AspCys: 2.606 ± 1.026
3.041AspAsp: 3.041 ± 0.775
2.606AspGlu: 2.606 ± 0.636
2.606AspPhe: 2.606 ± 0.444
3.041AspGly: 3.041 ± 0.815
0.869AspHis: 0.869 ± 0.661
3.475AspIle: 3.475 ± 0.669
2.606AspLys: 2.606 ± 0.787
5.647AspLeu: 5.647 ± 1.056
0.869AspMet: 0.869 ± 0.739
2.172AspAsn: 2.172 ± 0.671
2.172AspPro: 2.172 ± 0.48
2.172AspGln: 2.172 ± 0.434
3.041AspArg: 3.041 ± 0.769
2.606AspSer: 2.606 ± 1.228
3.475AspThr: 3.475 ± 0.946
1.303AspVal: 1.303 ± 0.37
0.869AspTrp: 0.869 ± 0.448
2.606AspTyr: 2.606 ± 0.793
0.0AspXaa: 0.0 ± 0.0
Glu
4.344GluAla: 4.344 ± 1.132
0.869GluCys: 0.869 ± 0.492
6.082GluAsp: 6.082 ± 1.631
11.729GluGlu: 11.729 ± 4.462
2.606GluPhe: 2.606 ± 1.012
4.344GluGly: 4.344 ± 0.883
2.172GluHis: 2.172 ± 0.81
7.819GluIle: 7.819 ± 1.761
9.991GluLys: 9.991 ± 1.564
6.95GluLeu: 6.95 ± 1.031
0.434GluMet: 0.434 ± 0.36
4.344GluAsn: 4.344 ± 1.946
3.041GluPro: 3.041 ± 0.954
4.344GluGln: 4.344 ± 1.258
0.869GluArg: 0.869 ± 0.417
6.95GluSer: 6.95 ± 1.533
3.475GluThr: 3.475 ± 0.871
1.738GluVal: 1.738 ± 0.971
0.434GluTrp: 0.434 ± 0.331
0.869GluTyr: 0.869 ± 0.692
0.0GluXaa: 0.0 ± 0.0
Phe
2.172PheAla: 2.172 ± 1.025
1.303PheCys: 1.303 ± 0.654
2.172PheAsp: 2.172 ± 0.81
0.869PheGlu: 0.869 ± 0.492
0.0PhePhe: 0.0 ± 0.0
1.303PheGly: 1.303 ± 0.742
0.434PheHis: 0.434 ± 0.408
3.041PheIle: 3.041 ± 1.041
3.91PheLys: 3.91 ± 1.273
4.778PheLeu: 4.778 ± 1.597
0.869PheMet: 0.869 ± 0.59
1.738PheAsn: 1.738 ± 0.47
1.738PhePro: 1.738 ± 0.835
1.303PheGln: 1.303 ± 0.37
3.475PheArg: 3.475 ± 0.573
2.606PheSer: 2.606 ± 1.155
3.041PheThr: 3.041 ± 0.595
1.738PheVal: 1.738 ± 0.886
0.869PheTrp: 0.869 ± 0.417
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.738GlyAla: 1.738 ± 1.181
0.869GlyCys: 0.869 ± 0.448
3.041GlyAsp: 3.041 ± 0.475
4.778GlyGlu: 4.778 ± 1.779
2.606GlyPhe: 2.606 ± 0.636
1.738GlyGly: 1.738 ± 0.47
1.303GlyHis: 1.303 ± 0.669
4.344GlyIle: 4.344 ± 0.695
4.344GlyLys: 4.344 ± 0.868
4.344GlyLeu: 4.344 ± 1.026
1.303GlyMet: 1.303 ± 0.51
3.91GlyAsn: 3.91 ± 1.993
1.738GlyPro: 1.738 ± 1.166
0.869GlyGln: 0.869 ± 0.636
1.738GlyArg: 1.738 ± 0.965
3.475GlySer: 3.475 ± 0.94
3.475GlyThr: 3.475 ± 1.099
2.606GlyVal: 2.606 ± 1.248
0.434GlyTrp: 0.434 ± 0.48
1.303GlyTyr: 1.303 ± 0.453
0.0GlyXaa: 0.0 ± 0.0
His
0.434HisAla: 0.434 ± 0.408
1.303HisCys: 1.303 ± 0.729
1.303HisAsp: 1.303 ± 0.813
0.434HisGlu: 0.434 ± 0.346
1.738HisPhe: 1.738 ± 0.886
0.434HisGly: 0.434 ± 0.331
1.303HisHis: 1.303 ± 0.37
2.172HisIle: 2.172 ± 1.285
2.172HisLys: 2.172 ± 0.748
1.738HisLeu: 1.738 ± 0.803
0.869HisMet: 0.869 ± 0.661
0.0HisAsn: 0.0 ± 0.0
0.869HisPro: 0.869 ± 0.392
0.434HisGln: 0.434 ± 0.408
0.434HisArg: 0.434 ± 0.408
1.303HisSer: 1.303 ± 0.37
0.434HisThr: 0.434 ± 0.408
0.869HisVal: 0.869 ± 0.583
0.869HisTrp: 0.869 ± 0.392
1.303HisTyr: 1.303 ± 0.669
0.0HisXaa: 0.0 ± 0.0
Ile
3.475IleAla: 3.475 ± 1.502
2.606IleCys: 2.606 ± 0.801
5.647IleAsp: 5.647 ± 2.199
6.082IleGlu: 6.082 ± 0.6
3.91IlePhe: 3.91 ± 0.979
4.344IleGly: 4.344 ± 1.448
0.869IleHis: 0.869 ± 0.832
4.344IleIle: 4.344 ± 1.741
7.819IleLys: 7.819 ± 2.149
7.385IleLeu: 7.385 ± 1.577
0.434IleMet: 0.434 ± 0.331
5.213IleAsn: 5.213 ± 1.915
4.778IlePro: 4.778 ± 1.619
3.91IleGln: 3.91 ± 1.759
4.344IleArg: 4.344 ± 0.883
4.344IleSer: 4.344 ± 1.211
3.041IleThr: 3.041 ± 0.884
3.475IleVal: 3.475 ± 1.554
0.434IleTrp: 0.434 ± 0.61
2.172IleTyr: 2.172 ± 0.675
0.0IleXaa: 0.0 ± 0.0
Lys
10.86LysAla: 10.86 ± 1.394
1.303LysCys: 1.303 ± 0.366
4.344LysAsp: 4.344 ± 1.774
12.163LysGlu: 12.163 ± 3.415
4.344LysPhe: 4.344 ± 0.71
5.647LysGly: 5.647 ± 0.839
0.0LysHis: 0.0 ± 0.0
10.86LysIle: 10.86 ± 0.766
14.77LysLys: 14.77 ± 4.063
5.647LysLeu: 5.647 ± 1.841
0.434LysMet: 0.434 ± 0.416
5.647LysAsn: 5.647 ± 1.59
5.647LysPro: 5.647 ± 1.162
3.91LysGln: 3.91 ± 1.162
3.041LysArg: 3.041 ± 0.681
4.778LysSer: 4.778 ± 2.32
6.95LysThr: 6.95 ± 1.644
4.778LysVal: 4.778 ± 1.364
0.0LysTrp: 0.0 ± 0.0
3.041LysTyr: 3.041 ± 1.216
0.0LysXaa: 0.0 ± 0.0
Leu
3.91LeuAla: 3.91 ± 0.695
0.869LeuCys: 0.869 ± 0.417
3.041LeuAsp: 3.041 ± 1.056
7.385LeuGlu: 7.385 ± 2.164
1.303LeuPhe: 1.303 ± 0.6
7.385LeuGly: 7.385 ± 1.9
2.172LeuHis: 2.172 ± 0.958
6.082LeuIle: 6.082 ± 1.429
7.385LeuLys: 7.385 ± 2.75
9.123LeuLeu: 9.123 ± 0.958
3.91LeuMet: 3.91 ± 1.521
5.213LeuAsn: 5.213 ± 2.064
2.606LeuPro: 2.606 ± 0.444
4.344LeuGln: 4.344 ± 1.278
1.303LeuArg: 1.303 ± 1.223
7.819LeuSer: 7.819 ± 1.734
6.082LeuThr: 6.082 ± 0.958
2.172LeuVal: 2.172 ± 1.097
0.0LeuTrp: 0.0 ± 0.0
3.041LeuTyr: 3.041 ± 0.817
0.0LeuXaa: 0.0 ± 0.0
Met
1.738MetAla: 1.738 ± 0.47
0.0MetCys: 0.0 ± 0.0
2.606MetAsp: 2.606 ± 0.636
1.738MetGlu: 1.738 ± 0.896
1.303MetPhe: 1.303 ± 0.473
0.434MetGly: 0.434 ± 0.346
0.0MetHis: 0.0 ± 0.0
1.303MetIle: 1.303 ± 0.453
2.172MetLys: 2.172 ± 1.004
1.738MetLeu: 1.738 ± 0.652
0.0MetMet: 0.0 ± 0.0
1.738MetAsn: 1.738 ± 0.502
0.434MetPro: 0.434 ± 0.416
1.738MetGln: 1.738 ± 0.502
0.0MetArg: 0.0 ± 0.0
0.869MetSer: 0.869 ± 0.821
1.303MetThr: 1.303 ± 0.741
2.172MetVal: 2.172 ± 0.639
0.0MetTrp: 0.0 ± 0.0
0.869MetTyr: 0.869 ± 0.692
0.0MetXaa: 0.0 ± 0.0
Asn
1.303AsnAla: 1.303 ± 0.37
0.434AsnCys: 0.434 ± 0.408
2.606AsnAsp: 2.606 ± 1.149
4.344AsnGlu: 4.344 ± 0.754
1.738AsnPhe: 1.738 ± 0.784
2.172AsnGly: 2.172 ± 1.089
0.869AsnHis: 0.869 ± 0.583
5.213AsnIle: 5.213 ± 1.652
6.95AsnLys: 6.95 ± 2.368
5.647AsnLeu: 5.647 ± 1.097
1.303AsnMet: 1.303 ± 0.473
3.475AsnAsn: 3.475 ± 1.332
3.475AsnPro: 3.475 ± 1.134
2.172AsnGln: 2.172 ± 1.013
2.606AsnArg: 2.606 ± 1.71
4.778AsnSer: 4.778 ± 2.748
4.344AsnThr: 4.344 ± 1.438
2.172AsnVal: 2.172 ± 1.062
0.434AsnTrp: 0.434 ± 0.416
2.606AsnTyr: 2.606 ± 0.806
0.0AsnXaa: 0.0 ± 0.0
Pro
1.738ProAla: 1.738 ± 0.774
0.434ProCys: 0.434 ± 0.48
0.434ProAsp: 0.434 ± 0.331
5.647ProGlu: 5.647 ± 0.716
1.303ProPhe: 1.303 ± 0.758
1.738ProGly: 1.738 ± 0.896
2.172ProHis: 2.172 ± 1.141
2.606ProIle: 2.606 ± 0.563
7.385ProLys: 7.385 ± 2.834
4.778ProLeu: 4.778 ± 1.545
0.869ProMet: 0.869 ± 0.661
3.041ProAsn: 3.041 ± 1.192
2.172ProPro: 2.172 ± 1.511
1.303ProGln: 1.303 ± 0.6
0.434ProArg: 0.434 ± 0.408
5.213ProSer: 5.213 ± 1.53
2.172ProThr: 2.172 ± 1.025
2.172ProVal: 2.172 ± 0.958
0.434ProTrp: 0.434 ± 0.331
0.869ProTyr: 0.869 ± 0.692
0.0ProXaa: 0.0 ± 0.0
Gln
1.738GlnAla: 1.738 ± 0.969
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.041GlnGlu: 3.041 ± 0.475
2.172GlnPhe: 2.172 ± 0.434
2.606GlnGly: 2.606 ± 1.176
0.869GlnHis: 0.869 ± 0.392
3.475GlnIle: 3.475 ± 0.997
3.91GlnLys: 3.91 ± 1.186
3.91GlnLeu: 3.91 ± 0.829
0.434GlnMet: 0.434 ± 0.408
3.041GlnAsn: 3.041 ± 2.405
2.606GlnPro: 2.606 ± 1.152
3.475GlnGln: 3.475 ± 0.798
2.606GlnArg: 2.606 ± 0.787
3.041GlnSer: 3.041 ± 1.766
3.475GlnThr: 3.475 ± 0.738
4.344GlnVal: 4.344 ± 1.072
0.434GlnTrp: 0.434 ± 0.331
0.434GlnTyr: 0.434 ± 0.346
0.0GlnXaa: 0.0 ± 0.0
Arg
2.172ArgAla: 2.172 ± 1.511
0.434ArgCys: 0.434 ± 0.346
0.869ArgAsp: 0.869 ± 0.491
2.172ArgGlu: 2.172 ± 0.675
1.738ArgPhe: 1.738 ± 0.594
0.869ArgGly: 0.869 ± 0.661
0.869ArgHis: 0.869 ± 0.417
1.303ArgIle: 1.303 ± 0.742
3.475ArgLys: 3.475 ± 0.513
3.475ArgLeu: 3.475 ± 0.658
1.738ArgMet: 1.738 ± 0.835
1.303ArgAsn: 1.303 ± 0.453
1.738ArgPro: 1.738 ± 0.784
0.869ArgGln: 0.869 ± 0.448
1.738ArgArg: 1.738 ± 0.622
2.606ArgSer: 2.606 ± 1.11
2.606ArgThr: 2.606 ± 1.228
2.172ArgVal: 2.172 ± 0.765
1.303ArgTrp: 1.303 ± 0.669
1.738ArgTyr: 1.738 ± 1.011
0.0ArgXaa: 0.0 ± 0.0
Ser
1.303SerAla: 1.303 ± 0.8
0.0SerCys: 0.0 ± 0.0
6.082SerAsp: 6.082 ± 1.473
6.95SerGlu: 6.95 ± 1.88
2.606SerPhe: 2.606 ± 1.2
4.778SerGly: 4.778 ± 0.762
0.869SerHis: 0.869 ± 0.437
6.082SerIle: 6.082 ± 1.605
9.123SerLys: 9.123 ± 1.658
7.385SerLeu: 7.385 ± 3.188
2.172SerMet: 2.172 ± 0.719
3.041SerAsn: 3.041 ± 1.222
1.303SerPro: 1.303 ± 0.6
3.91SerGln: 3.91 ± 1.602
2.172SerArg: 2.172 ± 0.82
7.385SerSer: 7.385 ± 2.285
3.475SerThr: 3.475 ± 1.107
1.738SerVal: 1.738 ± 1.015
0.0SerTrp: 0.0 ± 0.0
2.172SerTyr: 2.172 ± 1.223
0.0SerXaa: 0.0 ± 0.0
Thr
1.303ThrAla: 1.303 ± 0.573
0.869ThrCys: 0.869 ± 0.417
2.606ThrAsp: 2.606 ± 1.2
6.082ThrGlu: 6.082 ± 1.583
0.869ThrPhe: 0.869 ± 0.815
2.606ThrGly: 2.606 ± 0.602
0.869ThrHis: 0.869 ± 0.661
6.082ThrIle: 6.082 ± 1.392
5.213ThrLys: 5.213 ± 0.823
3.475ThrLeu: 3.475 ± 0.952
1.738ThrMet: 1.738 ± 0.734
4.344ThrAsn: 4.344 ± 1.027
2.172ThrPro: 2.172 ± 0.509
4.344ThrGln: 4.344 ± 1.704
2.172ThrArg: 2.172 ± 0.593
4.778ThrSer: 4.778 ± 2.666
2.606ThrThr: 2.606 ± 1.344
2.172ThrVal: 2.172 ± 0.606
0.434ThrTrp: 0.434 ± 0.48
0.869ThrTyr: 0.869 ± 0.437
0.0ThrXaa: 0.0 ± 0.0
Val
2.172ValAla: 2.172 ± 0.675
0.869ValCys: 0.869 ± 0.661
2.172ValAsp: 2.172 ± 0.643
2.606ValGlu: 2.606 ± 1.417
2.606ValPhe: 2.606 ± 1.18
2.172ValGly: 2.172 ± 0.937
1.738ValHis: 1.738 ± 0.502
3.041ValIle: 3.041 ± 1.082
5.647ValLys: 5.647 ± 1.635
0.869ValLeu: 0.869 ± 0.437
1.738ValMet: 1.738 ± 0.763
3.475ValAsn: 3.475 ± 1.807
2.172ValPro: 2.172 ± 1.097
1.303ValGln: 1.303 ± 0.473
2.606ValArg: 2.606 ± 0.886
2.172ValSer: 2.172 ± 1.072
0.434ValThr: 0.434 ± 0.331
2.172ValVal: 2.172 ± 0.639
0.434ValTrp: 0.434 ± 0.408
3.041ValTyr: 3.041 ± 0.884
0.0ValXaa: 0.0 ± 0.0
Trp
0.869TrpAla: 0.869 ± 0.492
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.869TrpGly: 0.869 ± 0.392
0.0TrpHis: 0.0 ± 0.0
0.434TrpIle: 0.434 ± 0.346
0.434TrpLys: 0.434 ± 0.61
0.869TrpLeu: 0.869 ± 0.392
0.434TrpMet: 0.434 ± 0.331
0.869TrpAsn: 0.869 ± 0.417
0.869TrpPro: 0.869 ± 0.96
0.869TrpGln: 0.869 ± 0.661
0.434TrpArg: 0.434 ± 0.331
0.0TrpSer: 0.0 ± 0.0
0.869TrpThr: 0.869 ± 0.392
0.434TrpVal: 0.434 ± 0.331
0.0TrpTrp: 0.0 ± 0.0
0.434TrpTyr: 0.434 ± 0.346
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.172TyrAla: 2.172 ± 0.355
0.869TyrCys: 0.869 ± 0.492
0.869TyrAsp: 0.869 ± 0.815
1.738TyrGlu: 1.738 ± 0.835
1.738TyrPhe: 1.738 ± 0.731
1.303TyrGly: 1.303 ± 0.684
0.869TyrHis: 0.869 ± 0.417
1.303TyrIle: 1.303 ± 0.669
4.778TyrLys: 4.778 ± 1.721
3.041TyrLeu: 3.041 ± 0.815
0.434TyrMet: 0.434 ± 0.331
1.738TyrAsn: 1.738 ± 0.594
2.172TyrPro: 2.172 ± 0.815
0.869TyrGln: 0.869 ± 0.437
0.0TyrArg: 0.0 ± 0.0
3.041TyrSer: 3.041 ± 0.608
0.869TyrThr: 0.869 ± 0.448
1.738TyrVal: 1.738 ± 0.664
0.434TyrTrp: 0.434 ± 0.331
0.434TyrTyr: 0.434 ± 0.408
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2303 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski